30608:GOLPH3
gene id: 30608:GOLPH3
uniprot id: A0A8B7EH64
uniprot id: A0A8C5VHN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

30608:RARB
gene id: 30608:RARB
uniprot id: A0A8B7HUB3
uniprot id: A0A8C6ELK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

30608:GPAT4
gene id: 30608:GPAT4
uniprot id: A0A8B7H8E1
uniprot id: A0A8B7H8F1
uniprot id: A0A8B7HB04
uniprot id: A0A8B7WSB7
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

30608:USB1
gene id: 30608:USB1
uniprot id: A0A8B7EVU8
uniprot id: A0A8B7EVV3
uniprot id: A0A8B7EXU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2H phosphoesterase superfamily. USB1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate.

30608:SFMBT2
gene id: 30608:SFMBT2
uniprot id: A0A8B7ER47
names: Subcellular Location Annotation
messages: Nucleus

30608:ST3GAL1
gene id: 30608:ST3GAL1
uniprot id: A0A8B7HSF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

30608:ZCCHC8
gene id: 30608:ZCCHC8
uniprot id: A0A8B7WT09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC8 family.
messages: nucleoplasm

30608:KCNN3
gene id: 30608:KCNN3
uniprot id: A0A8B7GKA2
uniprot id: A0A8B7GKA4
uniprot id: A0A8B7GKX0
names: Subcellular Location Annotation
messages: Membrane

30608:LOC109729502
gene id: 30608:LOC109729502
uniprot id: A0A8B7WN64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

30608:MEN1
gene id: 30608:MEN1
uniprot id: A0A8B7H9T6
uniprot id: A0A8B7HCK2
uniprot id: A0A8C5ULZ8
names: Subcellular Location Annotation
messages: Nucleus

30608:VAT1
gene id: 30608:VAT1
uniprot id: A0A8C5XHA7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

30608:TGFBR1
gene id: 30608:TGFBR1
uniprot id: A0A8B7GN03
uniprot id: A0A8B7GNA5
uniprot id: A0A8C5Y1Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

30608:IMMP1L
gene id: 30608:IMMP1L
uniprot id: A0A8B7HTX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family.
messages: Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Mitochondrion inner membrane

30608:NAALAD2
gene id: 30608:NAALAD2
uniprot id: A0A8B7EFY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

30608:XRN2
gene id: 30608:XRN2
uniprot id: A0A8C5XCT4
names: Function
names: Similarity
messages: Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
messages: Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.

30608:KRT9
gene id: 30608:KRT9
uniprot id: A0A8B7GET9
names: Similarity
messages: Belongs to the intermediate filament family.

30608:GEMIN2
gene id: 30608:GEMIN2
uniprot id: A0A8B7GI29
uniprot id: A0A8B7GI36
uniprot id: A0A8B7GIF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gemin-2 family.
messages: Cytoplasm
messages: Part of the core SMN complex.
messages: The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.

30608:USP39
gene id: 30608:USP39
uniprot id: A0A8B7H0Y9
uniprot id: A0A8C5W990
names: Subcellular Location Annotation
messages: Nucleus

30608:NDUFB8
gene id: 30608:NDUFB8
uniprot id: A0A8B7GNN6
uniprot id: A0A8C5Y380
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

30608:LOC105864759
gene id: 30608:LOC105864759
uniprot id: A0A8B7FIM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105862428
gene id: 30608:LOC105862428
uniprot id: A0A8B7F887
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC109731099
gene id: 30608:LOC109731099
uniprot id: A0A8B7X9L5
names: Similarity
messages: Belongs to the CMC4 family.

30608:VPS51
gene id: 30608:VPS51
uniprot id: A0A8B7H9V8
uniprot id: A0A8B7H9W5
uniprot id: A0A8C5VKT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS51 family.
messages: Component of the Golgi-associated retrograde protein (GARP) complex. Component of the endosome-associated retrograde protein (EARP) complex.
messages: Endosome
messages: Involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. Acts as component of the EARP complex that is involved in endocytic recycling.
messages: Recycling endosome
messages: trans-Golgi network

30608:RASSF5
gene id: 30608:RASSF5
uniprot id: A0A8B7G2G1
names: Subcellular Location Annotation
messages: cytoskeleton

30608:PAIP2B
gene id: 30608:PAIP2B
uniprot id: A0A8B7FBU3
uniprot id: A0A8B7FC01
uniprot id: A0A8B7FCH8
names: Similarity
messages: Belongs to the PAIP2 family.

30608:PDLIM3
gene id: 30608:PDLIM3
uniprot id: A0A8B7HTI4
uniprot id: A0A8C6ED78
names: Subcellular Location Annotation
messages: Z line

30608:STK17B
gene id: 30608:STK17B
uniprot id: A0A8C5XE49
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:CEP170
gene id: 30608:CEP170
uniprot id: A0A8B7FE94
uniprot id: A0A8B7FE99
uniprot id: A0A8B7FEA4
uniprot id: A0A8B7FEB6
uniprot id: A0A8B7FEC1
uniprot id: A0A8B7FEI3
uniprot id: A0A8B7FEI8
uniprot id: A0A8B7FF94
uniprot id: A0A8B7FF99
uniprot id: A0A8B7FFA5
uniprot id: A0A8C5XDN1
uniprot id: A0A8C5XRD5
names: Similarity
messages: Belongs to the CEP170 family.

30608:LOC105869356
gene id: 30608:LOC105869356
uniprot id: A0A8B7G348
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:PHF10
gene id: 30608:PHF10
uniprot id: A0A8B7HKG4
uniprot id: A0A8B7HKH1
uniprot id: A0A8B7HLN5
uniprot id: A0A8B7HN08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAYP family.
messages: Nucleus

30608:UTP6
gene id: 30608:UTP6
uniprot id: A0A8B7EIU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP6 family.
messages: nucleolus

30608:SAP130
gene id: 30608:SAP130
uniprot id: A0A8B7FBB9
uniprot id: A0A8B7FC07
uniprot id: A0A8B7X9G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAP130 family.
messages: Nucleus

30608:RPS25
gene id: 30608:RPS25
uniprot id: A0A8B7GZ97
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS25 family.
messages: Component of the small ribosomal subunit.

30608:LOC105858304
gene id: 30608:LOC105858304
uniprot id: A0A8C5Y4W5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:DAP3
gene id: 30608:DAP3
uniprot id: A0A8B7X1C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS29 family.
messages: Mitochondrion

30608:WNT9B
gene id: 30608:WNT9B
uniprot id: A0A8C6EHD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

30608:LOC105862780
gene id: 30608:LOC105862780
uniprot id: A0A8B7F9T7
names: Similarity
messages: Belongs to the GST superfamily.

30608:LOC105876420
gene id: 30608:LOC105876420
uniprot id: A0A8B7H2H4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:SLC12A8
gene id: 30608:SLC12A8
uniprot id: A0A8B7HFM8
uniprot id: A0A8B7HFQ7
uniprot id: A0A8B7HG86
uniprot id: A0A8B7HIB3
uniprot id: A0A8C5YGB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

30608:ZNF830
gene id: 30608:ZNF830
uniprot id: A0A8B7I509
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus speckle

30608:ARPC1B
gene id: 30608:ARPC1B
uniprot id: A0A8B7FYA8
names: Function
names: Similarity
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

30608:CORO1A
gene id: 30608:CORO1A
uniprot id: A0A8B7GB33
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat coronin family.
messages: Binds actin.
messages: Membrane
messages: cell cortex
messages: cytoskeleton
messages: phagosome membrane

30608:HTR7
gene id: 30608:HTR7
uniprot id: A0A8B7GE78
uniprot id: A0A8B7GE84
uniprot id: A0A8B7GF07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ADGRD2
gene id: 30608:ADGRD2
uniprot id: A0A8B7XDB9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:CTBP2
gene id: 30608:CTBP2
uniprot id: A0A8B7HHW2
uniprot id: A0A8B7HKE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

30608:LOC105862333
gene id: 30608:LOC105862333
uniprot id: A0A8B7WU11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS25 family.
messages: Mitochondrion

30608:SERF2
gene id: 30608:SERF2
uniprot id: A0A8B7GH53
names: Similarity
messages: Belongs to the SERF family.

30608:GRM3
gene id: 30608:GRM3
uniprot id: A0A8B7HDG4
uniprot id: A0A8B7HDH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

30608:TMEM115
gene id: 30608:TMEM115
uniprot id: A0A8C5XTY6
names: Subcellular Location Annotation
messages: Membrane

30608:ODF1
gene id: 30608:ODF1
uniprot id: A0A8C5URI5
names: Function
messages: Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail.

30608:INPP5J
gene id: 30608:INPP5J
uniprot id: A0A8B7GA58
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.

30608:SMAD4
gene id: 30608:SMAD4
uniprot id: A0A8B7WRU1
uniprot id: A0A8B7WTA6
uniprot id: A0A8C5XP46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

30608:LEPROT
gene id: 30608:LEPROT
uniprot id: A0A8B7GIN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

30608:PIGB
gene id: 30608:PIGB
uniprot id: A0A8B7HLT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:FABP2
gene id: 30608:FABP2
uniprot id: A0A8B7FMQ9
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

30608:GPR137B
gene id: 30608:GPR137B
uniprot id: A0A8B7EJ81
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

30608:LOC105883369
gene id: 30608:LOC105883369
uniprot id: A0A8B7HUX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:RP2
gene id: 30608:RP2
uniprot id: A0A8B7FBB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
messages: Belongs to the TBCC family.
messages: Cell membrane
messages: Membrane

30608:LOC105872918
gene id: 30608:LOC105872918
uniprot id: A0A8B7GK46
uniprot id: A0A8C5V8L4
names: Subcellular Location Annotation
messages: Nucleus

30608:MAN1A1
gene id: 30608:MAN1A1
uniprot id: A0A8B7EIU1
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

30608:TMEM107
gene id: 30608:TMEM107
uniprot id: A0A8B7H423
uniprot id: A0A8C5XYL4
names: Subcellular Location Annotation
messages: Membrane

30608:MS4A5
gene id: 30608:MS4A5
uniprot id: A0A8C5XEG8
names: Similarity
messages: Belongs to the MS4A family.

30608:MINPP1
gene id: 30608:MINPP1
uniprot id: A0A8B7G7V4
uniprot id: A0A8B7G8D1
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

30608:LOC105856702
gene id: 30608:LOC105856702
uniprot id: A0A8B7EJV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ANAPC11
gene id: 30608:ANAPC11
uniprot id: A0A8B7I2G1
names: Similarity
messages: Belongs to the RING-box family.

30608:LOC105864586
gene id: 30608:LOC105864586
uniprot id: A0A8B7FHQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:FABP6
gene id: 30608:FABP6
uniprot id: A0A8C5XBJ5
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

30608:CCL5
gene id: 30608:CCL5
uniprot id: A0A8B7HSN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

30608:SKP1
gene id: 30608:SKP1
uniprot id: A0A8B7G5V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SKP1 family.
messages: Component of multiple SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complexes formed of CUL1, SKP1, RBX1 and a variable F-box domain-containing protein as substrate-specific subunit.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1.
messages: The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component.

30608:LOC105872581
gene id: 30608:LOC105872581
uniprot id: A0A8B7X3S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

30608:PTPN3
gene id: 30608:PTPN3
uniprot id: A0A8B7ECX0
uniprot id: A0A8B7EDJ9
uniprot id: A0A8C5W2I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: May act at junctions between the membrane and the cytoskeleton.
messages: cytoskeleton

30608:PPP2CB
gene id: 30608:PPP2CB
uniprot id: A0A8B7WTL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

30608:IQSEC1
gene id: 30608:IQSEC1
uniprot id: A0A8B7HRV7
uniprot id: A0A8B7HRW2
uniprot id: A0A8B7HRW7
uniprot id: A0A8B7HRX1
uniprot id: A0A8B7HRX5
uniprot id: A0A8B7HTV9
uniprot id: A0A8B7HTW3
uniprot id: A0A8B7HU69
uniprot id: A0A8C5VUN8
names: Similarity
messages: Belongs to the BRAG family.

30608:TIMP4
gene id: 30608:TIMP4
uniprot id: A0A8B7HUC0
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

30608:NADSYN1
gene id: 30608:NADSYN1
uniprot id: A0A8B7FV65
uniprot id: A0A8B7FVX3
uniprot id: A0A8B7FW03
uniprot id: A0A8C5VA45
names: Similarity
names: Subunit
messages: Homohexamer.
messages: In the C-terminal section; belongs to the NAD synthetase family.

30608:LOC105880095
gene id: 30608:LOC105880095
uniprot id: A0A8C5WBM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

30608:MGRN1
gene id: 30608:MGRN1
uniprot id: A0A8B7EV28
uniprot id: A0A8B7EV30
uniprot id: A0A8B7EV39
uniprot id: A0A8C5V7Q1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

30608:GRP
gene id: 30608:GRP
uniprot id: A0A8B7EZJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bombesin/neuromedin-B/ranatensin family.
messages: Secreted
messages: neuron projection

30608:NR1D1
gene id: 30608:NR1D1
uniprot id: A0A8C5UNF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

30608:MGA
gene id: 30608:MGA
uniprot id: A0A8B7GGN3
uniprot id: A0A8B7GH33
uniprot id: A0A8B7GHE1
uniprot id: A0A8B7GHI5
uniprot id: A0A8B7X2R7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

30608:LOC105871814
gene id: 30608:LOC105871814
uniprot id: A0A8B7GDW3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

30608:LOC109730160
gene id: 30608:LOC109730160
uniprot id: A0A8B7WZG7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:SLC17A7
gene id: 30608:SLC17A7
uniprot id: A0A8C6EEA6
names: Subcellular Location Annotation
messages: Membrane

30608:RPS6KA2
gene id: 30608:RPS6KA2
uniprot id: A0A8B7H6Y6
uniprot id: A0A8B7H6Y7
uniprot id: A0A8B7H6Y9
uniprot id: A0A8B7H6Z2
uniprot id: A0A8B7H9G3
uniprot id: A0A8B7X571
uniprot id: A0A8C6EG74
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

30608:RPS20
gene id: 30608:RPS20
uniprot id: A0A8B7H0M3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Component of the 40S small ribosomal subunit.

30608:E2F8
gene id: 30608:E2F8
uniprot id: A0A8B7FSX2
uniprot id: A0A8B7FSZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

30608:FAM46B
gene id: 30608:FAM46B
uniprot id: A0A8B7FDR6
names: Similarity
messages: Belongs to the TENT family.

30608:AKT3
gene id: 30608:AKT3
uniprot id: A0A8B7FED3
uniprot id: A0A8B7FED9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

30608:ATP12A
gene id: 30608:ATP12A
uniprot id: A0A8B7HBA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Membrane

30608:LOC105876413
gene id: 30608:LOC105876413
uniprot id: A0A8B7XAY7
names: Similarity
messages: Belongs to the Rab GDI family.

30608:PGAP1
gene id: 30608:PGAP1
uniprot id: A0A8B7H7B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

30608:LOC105864302
gene id: 30608:LOC105864302
uniprot id: A0A8B7FGJ3
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

30608:KCNJ8
gene id: 30608:KCNJ8
uniprot id: A0A8C5VDV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

30608:SLC25A22
gene id: 30608:SLC25A22
uniprot id: A0A8C5ULT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:CEP57
gene id: 30608:CEP57
uniprot id: A0A8B7EXN6
uniprot id: A0A8C5VZV3
names: Similarity
messages: Belongs to the translokin family.

30608:PRRT1
gene id: 30608:PRRT1
uniprot id: A0A8B7ENU3
names: Similarity
messages: Belongs to the CD225/Dispanin family.

30608:TMEM225B
gene id: 30608:TMEM225B
uniprot id: A0A8B7FZ13
uniprot id: A0A8B7G083
names: Subcellular Location Annotation
messages: Membrane

30608:KCNMB3
gene id: 30608:KCNMB3
uniprot id: A0A8B7EDK2
uniprot id: A0A8C6ELA4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KCNMB (TC 8.A.14.1) family.
messages: Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB per KCNMA1 tetramer.
messages: Membrane
messages: N-glycosylated.
messages: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

30608:E2F1
gene id: 30608:E2F1
uniprot id: A0A8B7FP21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

30608:MUC17
gene id: 30608:MUC17
uniprot id: A0A8B7WPL3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:HS6ST3
gene id: 30608:HS6ST3
uniprot id: A0A8B7GPU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

30608:CD3D
gene id: 30608:CD3D
uniprot id: A0A8B7GZD0
uniprot id: A0A8B7H195
uniprot id: A0A8C6EFE5
names: Subcellular Location Annotation
messages: Membrane

30608:GNPDA1
gene id: 30608:GNPDA1
uniprot id: A0A8B7F9A1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

30608:OSBPL10
gene id: 30608:OSBPL10
uniprot id: A0A8B7GPT8
uniprot id: A0A8B7WNL8
uniprot id: A0A8B7WNN9
uniprot id: A0A8B7WNR6
names: Similarity
messages: Belongs to the OSBP family.

30608:SELP
gene id: 30608:SELP
uniprot id: A0A8B7HNP8
uniprot id: A0A8B7HQB3
uniprot id: A0A8B7HR55
uniprot id: A0A8C5XX00
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selectin/LECAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:LOC105865922
gene id: 30608:LOC105865922
uniprot id: A0A8B7FPS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Odorant receptor.

30608:MAN2C1
gene id: 30608:MAN2C1
uniprot id: A0A8B7E9K8
uniprot id: A0A8B7E9P3
uniprot id: A0A8B7ECE0
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

30608:OSBP
gene id: 30608:OSBP
uniprot id: A0A8B7G153
uniprot id: A0A8C5UNS7
names: Similarity
messages: Belongs to the OSBP family.

30608:ADM
gene id: 30608:ADM
uniprot id: A0A8C5Y4W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adrenomedullin family.
messages: Secreted

30608:TUBA8
gene id: 30608:TUBA8
uniprot id: A0A8C5W9S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

30608:LOC105869332
gene id: 30608:LOC105869332
uniprot id: A0A8B7XFY8
names: Similarity
messages: Belongs to the AKAP110 family.

30608:SRD5A1
gene id: 30608:SRD5A1
uniprot id: A0A8B7EWJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
messages: Membrane
messages: Microsome membrane

30608:GBX1
gene id: 30608:GBX1
uniprot id: A0A8B7HWH4
names: Subcellular Location Annotation
messages: Nucleus

30608:SPSB2
gene id: 30608:SPSB2
uniprot id: A0A8B7G1M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

30608:LOC105861987
gene id: 30608:LOC105861987
uniprot id: A0A8B7F6G9
uniprot id: A0A8B7F6H2
uniprot id: A0A8B7F6J4
uniprot id: A0A8B7F6L7
uniprot id: A0A8B7F6M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

30608:RPS13
gene id: 30608:RPS13
uniprot id: A0A8B7HG98
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

30608:MRPL44
gene id: 30608:MRPL44
uniprot id: A0A8B7G335
uniprot id: A0A8B7G4I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease III family. Mitochondrion-specific ribosomal protein mL44 subfamily.
messages: Mitochondrion

30608:PER3
gene id: 30608:PER3
uniprot id: A0A8B7I7H0
uniprot id: A0A8B7I9I4
uniprot id: A0A8B7IAU8
uniprot id: A0A8B7WQB7
uniprot id: A0A8B7WQG1
uniprot id: A0A8B7WRU0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:TMEM150A
gene id: 30608:TMEM150A
uniprot id: A0A8B7H0X6
uniprot id: A0A8B7H0Y4
uniprot id: A0A8B7H2Y5
uniprot id: A0A8C5VAS7
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105883427
gene id: 30608:LOC105883427
uniprot id: A0A8B7HV30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105874769
gene id: 30608:LOC105874769
uniprot id: A0A8B7GSM3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

30608:LOC105881121
gene id: 30608:LOC105881121
uniprot id: A0A8C5V739
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

30608:UBE2L6
gene id: 30608:UBE2L6
uniprot id: A0A8C5VVC4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:PTPRD
gene id: 30608:PTPRD
uniprot id: A0A8B7XAC3
uniprot id: A0A8B7XAC8
uniprot id: A0A8B7XAD4
uniprot id: A0A8B7XAD5
uniprot id: A0A8B7XAD8
uniprot id: A0A8B7XAE0
uniprot id: A0A8B7XAE1
uniprot id: A0A8B7XAE4
uniprot id: A0A8B7XAE6
uniprot id: A0A8B7XAE9
uniprot id: A0A8B7XAF1
uniprot id: A0A8B7XAF4
uniprot id: A0A8B7XAF5
uniprot id: A0A8B7XAF9
uniprot id: A0A8B7XAG0
uniprot id: A0A8B7XAG4
uniprot id: A0A8B7XAG6
uniprot id: A0A8B7XB49
uniprot id: A0A8B7XB55
uniprot id: A0A8B7XB60
uniprot id: A0A8B7XB65
uniprot id: A0A8B7XB70
uniprot id: A0A8B7XB75
uniprot id: A0A8B7XB80
uniprot id: A0A8B7XB85
uniprot id: A0A8B7XC21
uniprot id: A0A8B7XC25
uniprot id: A0A8B7XC29
uniprot id: A0A8B7XC34
uniprot id: A0A8B7XC39
uniprot id: A0A8B7XC45
uniprot id: A0A8B7XC51
uniprot id: A0A8B7XC56
uniprot id: A0A8B7XC61
uniprot id: A0A8B7XCI5
uniprot id: A0A8B7XCI9
uniprot id: A0A8B7XCJ4
uniprot id: A0A8B7XCJ9
uniprot id: A0A8B7XCK5
uniprot id: A0A8B7XCK9
uniprot id: A0A8B7XCL5
uniprot id: A0A8B7XCM0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

30608:LOC105864641
gene id: 30608:LOC105864641
uniprot id: A0A8B7FHS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SOAT2
gene id: 30608:SOAT2
uniprot id: A0A8B7G8N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:ST8SIA5
gene id: 30608:ST8SIA5
uniprot id: A0A8B7EZD7
uniprot id: A0A8B7F1L3
uniprot id: A0A8C5YBH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

30608:LYPD5
gene id: 30608:LYPD5
uniprot id: A0A8B7G3S2
uniprot id: A0A8B7G4K1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:AURKAIP1
gene id: 30608:AURKAIP1
uniprot id: A0A8B7H610
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mS38 family.

30608:GNA13
gene id: 30608:GNA13
uniprot id: A0A8C5XMT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

30608:MICAL3
gene id: 30608:MICAL3
uniprot id: A0A8B7F5Y4
uniprot id: A0A8B7F5Y7
uniprot id: A0A8B7F5Z0
uniprot id: A0A8B7F5Z1
uniprot id: A0A8B7F5Z3
uniprot id: A0A8B7F5Z5
uniprot id: A0A8B7F5Z6
uniprot id: A0A8B7F5Z7
uniprot id: A0A8B7F5Z9
uniprot id: A0A8B7F600
uniprot id: A0A8B7F601
uniprot id: A0A8B7F603
uniprot id: A0A8B7F609
uniprot id: A0A8B7F613
uniprot id: A0A8B7F618
uniprot id: A0A8B7F625
uniprot id: A0A8B7F633
uniprot id: A0A8B7X5I8
uniprot id: A0A8B7X5J1
uniprot id: A0A8B7X7I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

30608:LOC105864598
gene id: 30608:LOC105864598
uniprot id: A0A8B7FHT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SPOPL
gene id: 30608:SPOPL
uniprot id: A0A8B7EML0
names: Similarity
messages: Belongs to the Tdpoz family.

30608:TSHZ2
gene id: 30608:TSHZ2
uniprot id: A0A8B7FGX0
uniprot id: A0A8C5XZ74
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

30608:KLC3
gene id: 30608:KLC3
uniprot id: A0A8B7G3Y7
uniprot id: A0A8C5UIP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

30608:LOC105885969
gene id: 30608:LOC105885969
uniprot id: A0A8B7X1Z9
names: Subcellular Location Annotation
messages: Membrane

30608:MYOG
gene id: 30608:MYOG
uniprot id: A0A8B7FYG4
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC109730735
gene id: 30608:LOC109730735
uniprot id: A0A8B7X3Z7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

30608:GHITM
gene id: 30608:GHITM
uniprot id: A0A8B7WM32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

30608:IRX4
gene id: 30608:IRX4
uniprot id: A0A8C5W7A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

30608:NXF3
gene id: 30608:NXF3
uniprot id: A0A8B7I0S8
uniprot id: A0A8B7WYP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm

30608:HPS6
gene id: 30608:HPS6
uniprot id: A0A8B7GPR4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6. Interacts with HPS5 and HPS3. Interacts with biogenesis of lysosome-related organelles complex-1 (BLOC1). Interacts with AP-3 complex.
messages: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
messages: Microsome membrane

30608:SH3RF2
gene id: 30608:SH3RF2
uniprot id: A0A8C5VIL5
names: Similarity
messages: Belongs to the SH3RF family.

30608:KAT8
gene id: 30608:KAT8
uniprot id: A0A8B7GAP3
uniprot id: A0A8B7GBQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

30608:LOC105865671
gene id: 30608:LOC105865671
uniprot id: A0A8B7FMA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Odorant receptor.

30608:NOVA1
gene id: 30608:NOVA1
uniprot id: A0A8B7GZ10
uniprot id: A0A8B7GZ13
uniprot id: A0A8B7GZ22
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with PTBP2; the interaction is direct.
messages: Nucleus

30608:PHB
gene id: 30608:PHB
uniprot id: A0A8C6EK19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

30608:FAM98B
gene id: 30608:FAM98B
uniprot id: A0A8B7X1F2
names: Similarity
messages: Belongs to the FAM98 family.

30608:ADCK5
gene id: 30608:ADCK5
uniprot id: A0A8C5V3W8
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

30608:DEFB115
gene id: 30608:DEFB115
uniprot id: A0A8B7WQT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

30608:RBP1
gene id: 30608:RBP1
uniprot id: A0A8B7G694
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

30608:HOXD1
gene id: 30608:HOXD1
uniprot id: A0A8C5XSY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Labial subfamily.
messages: Nucleus

30608:STAC3
gene id: 30608:STAC3
uniprot id: A0A8B7H7K5
uniprot id: A0A8C5V1E8
names: Subcellular Location Annotation
messages: sarcolemma

30608:TRPV3
gene id: 30608:TRPV3
uniprot id: A0A8B7HD57
names: Subcellular Location Annotation
messages: Membrane

30608:HAGHL
gene id: 30608:HAGHL
uniprot id: A0A8B7EFM4
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

30608:TRPT1
gene id: 30608:TRPT1
uniprot id: A0A8B7X394
uniprot id: A0A8B7X455
uniprot id: A0A8C5XKQ5
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

30608:PEX13
gene id: 30608:PEX13
uniprot id: A0A8B7GCG1
names: Similarity
messages: Belongs to the peroxin-13 family.

30608:ARX
gene id: 30608:ARX
uniprot id: A0A8C5Y2E3
names: Subcellular Location Annotation
messages: Nucleus

30608:POLR3C
gene id: 30608:POLR3C
uniprot id: A0A8B7G5B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

30608:CALB1
gene id: 30608:CALB1
uniprot id: A0A8C5UXC7
names: Function
names: Similarity
messages: Belongs to the calbindin family.
messages: Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.

30608:LOC105874389
gene id: 30608:LOC105874389
uniprot id: A0A8B7GSJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PRKRIP1
gene id: 30608:PRKRIP1
uniprot id: A0A8B7FYE5
names: Similarity
messages: Belongs to the PRKRIP1 family.

30608:TIGD2
gene id: 30608:TIGD2
uniprot id: A0A8B7WXM5
names: Subcellular Location Annotation
messages: Nucleus

30608:ACTBL2
gene id: 30608:ACTBL2
uniprot id: A0A8B7H6K4
uniprot id: A0A8C5XED3
names: Similarity
messages: Belongs to the actin family.

30608:LOC105859908
gene id: 30608:LOC105859908
uniprot id: A0A8B7EY89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:DSC1
gene id: 30608:DSC1
uniprot id: A0A8B7EED4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

30608:EXO1
gene id: 30608:EXO1
uniprot id: A0A8B7FFT5
uniprot id: A0A8B7WP62
uniprot id: A0A8C5Y9L5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

30608:RPL39
gene id: 30608:RPL39
uniprot id: A0A8B7EL98
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

30608:ADORA2A
gene id: 30608:ADORA2A
uniprot id: A0A8B7F9Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

30608:DAZAP2
gene id: 30608:DAZAP2
uniprot id: A0A8B7G6R2
uniprot id: A0A8B7G6X6
uniprot id: A0A8B7X673
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus speckle
messages: nuclear body

30608:FNIP1
gene id: 30608:FNIP1
uniprot id: A0A8B7WRR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

30608:LOC105861232
gene id: 30608:LOC105861232
uniprot id: A0A8B7F414
names: Similarity
messages: Belongs to the GAGE family.

30608:KDELC1
gene id: 30608:KDELC1
uniprot id: A0A8B7FGA8
names: Similarity
messages: Belongs to the KDELC family.

30608:DMAP1
gene id: 30608:DMAP1
uniprot id: A0A8C5VWH8
names: Subcellular Location Annotation
messages: Nucleus

30608:PA2G4
gene id: 30608:PA2G4
uniprot id: A0A8B7FJR8
names: Similarity
messages: Belongs to the peptidase M24 family.

30608:AU129 gp13
gene id: 30608:AU129_gp13
uniprot id: A0A0U2JG85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Membrane
messages: Mitochondrion inner membrane

30608:LOC105864626
gene id: 30608:LOC105864626
uniprot id: A0A8B7FHY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Odorant receptor.

30608:LOC105878965
gene id: 30608:LOC105878965
uniprot id: A0A8B7HBY1
uniprot id: A0A8B7WMJ7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

30608:EGFL6
gene id: 30608:EGFL6
uniprot id: A0A8B7HQX3
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:RPL3L
gene id: 30608:RPL3L
uniprot id: A0A8B7EWQ7
uniprot id: A0A8C5XPJ5
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

30608:LOC105884123
gene id: 30608:LOC105884123
uniprot id: A0A8B7HYH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:BRCC3
gene id: 30608:BRCC3
uniprot id: A0A8B7WZT8
uniprot id: A0A8B7X109
uniprot id: A0A8C5Y4P9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M67A family. BRCC36 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Component of the ARISC complex, at least composed of UIMC1/RAP80, ABRAXAS1, BRCC3/BRCC36, BABAM2 and BABAM1/NBA1. Component of the BRCA1-A complex, at least composed of BRCA1, BARD1, UIMC1/RAP80, ABRAXAS1, BRCC3/BRCC36, BABAM2 and BABAM1/NBA1. In the BRCA1-A complex, interacts directly with ABRAXAS1 and BABAM2. Component of the BRISC complex, at least composed of ABRAXAS2, BRCC3/BRCC36, BABAM2 and BABAM1/NBA1. Identified in a complex with SHMT2 and the other subunits of the BRISC complex. In the BRISC complex, interacts directly with ABRAXAS2. Identified in a complex with ABRAXAS2 and NUMA1. The BRISC complex interacts with the CSN complex. Component of the BRCA1/BRCA2 containing complex (BRCC), which also contains BRCA1, BRCA2, BARD1, BABAM2 and RAD51. BRCC is a ubiquitin E3 ligase complex that enhances cellular survival following DNA damage. Interacts with BRCA1. Binds polyubiquitin. Interacts with PWWP2B. Interacts with HDAC1; this interaction is enhanced in the presence of PWWP2B.
messages: Cytoplasm
messages: Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the brca1-bard1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). Catalytic subunit of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates. Mediates the specific 'Lys-63'-specific deubiquitination associated with the COP9 signalosome complex (CSN), via the interaction of the BRISC complex with the CSN complex. The BRISC complex is required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1.
messages: Nucleus
messages: spindle pole

30608:ZNF75A
gene id: 30608:ZNF75A
uniprot id: A0A8B7EV76
uniprot id: A0A8B7EV83
uniprot id: A0A8B7EX72
names: Subcellular Location Annotation
messages: Nucleus

30608:DPEP3
gene id: 30608:DPEP3
uniprot id: A0A8B7ETF0
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105860778
gene id: 30608:LOC105860778
uniprot id: A0A8B7F225
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:LOC105855009
gene id: 30608:LOC105855009
uniprot id: A0A8B7WVL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPE family.
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated with ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

30608:SLCO3A1
gene id: 30608:SLCO3A1
uniprot id: A0A8C5UWI4
uniprot id: A0A8C5VYH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

30608:FXYD2
gene id: 30608:FXYD2
uniprot id: A0A8B7GZF1
uniprot id: A0A8C5Y9W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FXYD family.
messages: May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.
messages: Membrane
messages: Regulatory subunit of the sodium/potassium-transporting ATPase which is composed of a catalytic alpha subunit, an auxiliary non-catalytic beta subunit and an additional regulatory subunit.

30608:COL18A1
gene id: 30608:COL18A1
uniprot id: A0A8B7HHC2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:AGL
gene id: 30608:AGL
uniprot id: A0A8B7F828
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

30608:TAGLN2
gene id: 30608:TAGLN2
uniprot id: A0A8B7F9I6
names: Similarity
messages: Belongs to the calponin family.

30608:THBD
gene id: 30608:THBD
uniprot id: A0A8B7EJ21
names: Caution
names: Function
names: Subunit
messages: Interacts with ITGAL, ITGAM and ITGB2.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

30608:MEF2B
gene id: 30608:MEF2B
uniprot id: A0A8B7EPD9
names: Subcellular Location Annotation
messages: Nucleus

30608:ARHGEF1
gene id: 30608:ARHGEF1
uniprot id: A0A8B7FX28
uniprot id: A0A8B7FXU6
uniprot id: A0A8B7FXX5
names: Subcellular Location Annotation
messages: Membrane

30608:P2RX7
gene id: 30608:P2RX7
uniprot id: A0A8B7HK02
uniprot id: A0A8B7WUZ9
uniprot id: A0A8C5USK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P2X receptor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

30608:ST18
gene id: 30608:ST18
uniprot id: A0A8B7I3X8
uniprot id: A0A8B7I3Y4
uniprot id: A0A8B7I3Z8
uniprot id: A0A8B7I5Y7
uniprot id: A0A8B7I702
uniprot id: A0A8B7XA19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

30608:SNAP23
gene id: 30608:SNAP23
uniprot id: A0A8B7GGU2
uniprot id: A0A8B7GHJ0
uniprot id: A0A8B7GHP7
uniprot id: A0A8B7GHQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Membrane
messages: synaptosome

30608:CDH7
gene id: 30608:CDH7
uniprot id: A0A8C5VYT2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

30608:ACKR3
gene id: 30608:ACKR3
uniprot id: A0A8C5UYE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NAPB
gene id: 30608:NAPB
uniprot id: A0A8C5V9H4
uniprot id: A0A8C5VUM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

30608:PLP1
gene id: 30608:PLP1
uniprot id: A0A8B7HYN0
uniprot id: A0A8B7HYN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

30608:DYNC2LI1
gene id: 30608:DYNC2LI1
uniprot id: A0A8C5XMV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light intermediate chain family.
messages: centrosome
messages: cilium
messages: cilium axoneme
messages: cilium basal body

30608:FCN2
gene id: 30608:FCN2
uniprot id: A0A8B7HJJ4
names: Similarity
messages: Belongs to the ficolin lectin family.

30608:RHOT1
gene id: 30608:RHOT1
uniprot id: A0A8B7EEU5
uniprot id: A0A8B7EF02
uniprot id: A0A8B7EGS5
uniprot id: A0A8B7EH55
uniprot id: A0A8C6EHJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

30608:PGGT1B
gene id: 30608:PGGT1B
uniprot id: A0A8C5VQ90
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

30608:LOC105871892
gene id: 30608:LOC105871892
uniprot id: A0A8B7GEP3
uniprot id: A0A8B7GEY0
names: Similarity
messages: Belongs to the SPATA31 family.

30608:BANF2
gene id: 30608:BANF2
uniprot id: A0A8C5V7L7
names: Subcellular Location Annotation
messages: Nucleus

30608:DBT
gene id: 30608:DBT
uniprot id: A0A8C5VBZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

30608:ZFHX3
gene id: 30608:ZFHX3
uniprot id: A0A8B7ERS9
uniprot id: A0A8B7ERT4
uniprot id: A0A8B7ETU5
uniprot id: A0A8C5UPJ5
names: Subcellular Location Annotation
messages: Nucleus

30608:ATP6V0D1
gene id: 30608:ATP6V0D1
uniprot id: A0A8C5UZG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

30608:SAMD4B
gene id: 30608:SAMD4B
uniprot id: A0A8B7H3T6
uniprot id: A0A8C5UTJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

30608:REXO2
gene id: 30608:REXO2
uniprot id: A0A8C5W518
names: Similarity
messages: Belongs to the oligoribonuclease family.

30608:C22H19orf12
gene id: 30608:C22H19orf12
uniprot id: A0A8B7H339
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

30608:LOC105868769
gene id: 30608:LOC105868769
uniprot id: A0A8B7WT35
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105867754
gene id: 30608:LOC105867754
uniprot id: A0A8B7FW33
names: Subcellular Location Annotation
messages: Membrane

30608:GHRHR
gene id: 30608:GHRHR
uniprot id: A0A8B7EAW2
names: Subcellular Location Annotation
messages: Membrane

30608:STMN1
gene id: 30608:STMN1
uniprot id: A0A8B7FCK3
names: Similarity
messages: Belongs to the stathmin family.

30608:HSD3B2
gene id: 30608:HSD3B2
uniprot id: A0A8B7G519
uniprot id: A0A8B7G560
uniprot id: A0A8B7G6E4
names: Similarity
messages: Belongs to the 3-beta-HSD family.

30608:SLC44A2
gene id: 30608:SLC44A2
uniprot id: A0A8B7I5B5
uniprot id: A0A8B7I5E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

30608:LOC105885458
gene id: 30608:LOC105885458
uniprot id: A0A8B7I7T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LRP2
gene id: 30608:LRP2
uniprot id: A0A8C5V628
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:SV2C
gene id: 30608:SV2C
uniprot id: A0A8B7EHV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

30608:PYCRL
gene id: 30608:PYCRL
uniprot id: A0A8B7FIN8
uniprot id: A0A8B7FIS9
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

30608:GMPR
gene id: 30608:GMPR
uniprot id: A0A8B7FKE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

30608:TUBGCP6
gene id: 30608:TUBGCP6
uniprot id: A0A8B7X6A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: centrosome

30608:FGF16
gene id: 30608:FGF16
uniprot id: A0A8B7FQS5
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

30608:B4GALNT1
gene id: 30608:B4GALNT1
uniprot id: A0A8B7H7Q3
uniprot id: A0A8B7HA87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:LOC105864730
gene id: 30608:LOC105864730
uniprot id: A0A8B7FI72
uniprot id: A0A8B7X323
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

30608:RECQL4
gene id: 30608:RECQL4
uniprot id: A0A8B7G0M0
uniprot id: A0A8B7G0N9
uniprot id: A0A8B7G1Y4
uniprot id: A0A8B7X976
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

30608:LOC105884110
gene id: 30608:LOC105884110
uniprot id: A0A8B7I0J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:FBXO45
gene id: 30608:FBXO45
uniprot id: A0A8C5YG82
names: Similarity
messages: Belongs to the FBXO45/Fsn family.

30608:LOC105859343
gene id: 30608:LOC105859343
uniprot id: A0A8B7ETK8
names: Subcellular Location Annotation
messages: Membrane

30608:SH3GLB1
gene id: 30608:SH3GLB1
uniprot id: A0A8B7F5J5
uniprot id: A0A8B7F5J6
uniprot id: A0A8B7F5J8
uniprot id: A0A8B7F5J9
uniprot id: A0A8B7F5K1
uniprot id: A0A8B7F5K4
uniprot id: A0A8B7F5K7
uniprot id: A0A8B7F5L7
uniprot id: A0A8B7F5M2
uniprot id: A0A8C5VQ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Golgi apparatus membrane
messages: Midbody
messages: Mitochondrion outer membrane
messages: autophagosome membrane

30608:MRPL17
gene id: 30608:MRPL17
uniprot id: A0A8B7HV43
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

30608:MRPS12
gene id: 30608:MRPS12
uniprot id: A0A8B7H1Z6
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

30608:CPZ
gene id: 30608:CPZ
uniprot id: A0A8B7EZR7
uniprot id: A0A8B7WRT4
uniprot id: A0A8C5XW12
names: Caution
names: Similarity
messages: Belongs to the peptidase M14 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105874717
gene id: 30608:LOC105874717
uniprot id: A0A8B7GU84
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

30608:LOC105861267
gene id: 30608:LOC105861267
uniprot id: A0A8B7F2I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TMPRSS11D
gene id: 30608:TMPRSS11D
uniprot id: A0A8B7G4A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

30608:PLCB3
gene id: 30608:PLCB3
uniprot id: A0A8B7HCC4
names: Cofactor
names: Function
messages: Binds 1 Ca(2+) ion per subunit.
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

30608:ZNF706
gene id: 30608:ZNF706
uniprot id: A0A8C5VEM3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:LIN7A
gene id: 30608:LIN7A
uniprot id: A0A8B7X703
uniprot id: A0A8C5VR01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the lin-7 family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.
messages: Postsynaptic density membrane
messages: tight junction

30608:GTF2I
gene id: 30608:GTF2I
uniprot id: A0A8B7ERA8
uniprot id: A0A8B7ERA9
uniprot id: A0A8B7ERB4
uniprot id: A0A8B7ERC5
uniprot id: A0A8B7ET26
uniprot id: A0A8B7ETD5
uniprot id: A0A8B7WP03
names: Subcellular Location Annotation
messages: Nucleus

30608:YARS2
gene id: 30608:YARS2
uniprot id: A0A8B7I217
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

30608:KRT17
gene id: 30608:KRT17
uniprot id: A0A8B7GFL8
names: Similarity
messages: Belongs to the intermediate filament family.

30608:PTX4
gene id: 30608:PTX4
uniprot id: A0A8B7EUQ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105867930
gene id: 30608:LOC105867930
uniprot id: A0A8B7FWW0
names: Subcellular Location Annotation
messages: Membrane

30608:TIE1
gene id: 30608:TIE1
uniprot id: A0A8B7H4K9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:MYH11
gene id: 30608:MYH11
uniprot id: A0A8B7I4D1
uniprot id: A0A8B7I7G0
uniprot id: A0A8B7WNS3
uniprot id: A0A8B7WNT2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

30608:ITGA2
gene id: 30608:ITGA2
uniprot id: A0A8B7EM00
uniprot id: A0A8C5UQE0
uniprot id: A0A8C6EIU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

30608:PLK2
gene id: 30608:PLK2
uniprot id: A0A8C5VF91
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

30608:LOC105883461
gene id: 30608:LOC105883461
uniprot id: A0A8B7HVB8
uniprot id: A0A8B7HXG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105878283
gene id: 30608:LOC105878283
uniprot id: A0A8B7H8V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

30608:TAS2R1
gene id: 30608:TAS2R1
uniprot id: A0A8B7I6P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

30608:LOC109729818
gene id: 30608:LOC109729818
uniprot id: A0A8B7WSW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

30608:SPTBN1
gene id: 30608:SPTBN1
uniprot id: A0A8B7H9B4
uniprot id: A0A8B7HC26
uniprot id: A0A8C5XSZ5
uniprot id: A0A8C5YA37
names: Similarity
messages: Belongs to the spectrin family.

30608:IGFBP6
gene id: 30608:IGFBP6
uniprot id: A0A8B7G8P5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:LOC105875040
gene id: 30608:LOC105875040
uniprot id: A0A8B7GUD5
uniprot id: A0A8B7GVZ6
uniprot id: A0A8C5YCU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: Endoplasmic reticulum membrane
messages: Lysosome
messages: Membrane
messages: cytoskeleton
messages: phagosome

30608:NME3
gene id: 30608:NME3
uniprot id: A0A8B7EUW3
uniprot id: A0A8C6EEJ3
names: Similarity
messages: Belongs to the NDK family.

30608:LIN52
gene id: 30608:LIN52
uniprot id: A0A8B7EQG4
uniprot id: A0A8B7EQN5
uniprot id: A0A8B7EQP6
uniprot id: A0A8B7ES59
uniprot id: A0A8B7ESB3
uniprot id: A0A8B7ESM5
names: Similarity
messages: Belongs to the lin-52 family.

30608:LOC105856306
gene id: 30608:LOC105856306
uniprot id: A0A8B7XAP8
uniprot id: A0A8B7XCE7
uniprot id: A0A8C5YE83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.
messages: Secreted

30608:ETFA
gene id: 30608:ETFA
uniprot id: A0A8B7EJG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

30608:ACTR3
gene id: 30608:ACTR3
uniprot id: A0A8B7EK42
names: Similarity
messages: Belongs to the actin family.

30608:CLCF1
gene id: 30608:CLCF1
uniprot id: A0A8B7FUR2
uniprot id: A0A8B7FUX2
uniprot id: A0A8C5YAN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

30608:ERAP2
gene id: 30608:ERAP2
uniprot id: A0A8B7H0P4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

30608:TIMM22
gene id: 30608:TIMM22
uniprot id: A0A8B7EMC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex.
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

30608:RIBC2
gene id: 30608:RIBC2
uniprot id: A0A8B7X6K6
names: Similarity
messages: Belongs to the RIB43A family.

30608:SEC24D
gene id: 30608:SEC24D
uniprot id: A0A8B7HWZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

30608:C10H9orf78
gene id: 30608:C10H9orf78
uniprot id: A0A8C5VKE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TLS1 family.
messages: Nucleus

30608:TMEM35A
gene id: 30608:TMEM35A
uniprot id: A0A8B7GJM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

30608:GFAP
gene id: 30608:GFAP
uniprot id: A0A8C5VFL4
uniprot id: A0A8C6EKA0
names: Similarity
messages: Belongs to the intermediate filament family.

30608:ERBB2
gene id: 30608:ERBB2
uniprot id: A0A8B7GF50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

30608:TRPC3
gene id: 30608:TRPC3
uniprot id: A0A8B7HPE2
uniprot id: A0A8B7HPF0
uniprot id: A0A8B7HRT7
uniprot id: A0A8B7WKL1
uniprot id: A0A8C5USQ5
uniprot id: A0A8C5VLY1
names: Subcellular Location Annotation
messages: Membrane

30608:DYRK3
gene id: 30608:DYRK3
uniprot id: A0A8B7G1N1
uniprot id: A0A8B7G2K4
uniprot id: A0A8C5XRV2
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

30608:MTHFR
gene id: 30608:MTHFR
uniprot id: A0A8B7HS77
uniprot id: A0A8B7HU83
uniprot id: A0A8B7HUH7
uniprot id: A0A8C5UPD0
uniprot id: A0A8C5YEU2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

30608:LOC105883400
gene id: 30608:LOC105883400
uniprot id: A0A8B7HV12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CCR1
gene id: 30608:CCR1
uniprot id: A0A8B7GSX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

30608:SARM1
gene id: 30608:SARM1
uniprot id: A0A8C5VKP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SARM1 family.
messages: axon

30608:LOC105874214
gene id: 30608:LOC105874214
uniprot id: A0A8B7GQA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

30608:CSNK1G1
gene id: 30608:CSNK1G1
uniprot id: A0A8B7FX73
uniprot id: A0A8B7FX76
uniprot id: A0A8B7FX78
uniprot id: A0A8B7FX81
uniprot id: A0A8B7FXD3
uniprot id: A0A8B7FXD8
uniprot id: A0A8B7FY65
uniprot id: A0A8B7FY96
uniprot id: A0A8B7FY99
uniprot id: A0A8B7X1N1
uniprot id: A0A8C5VWD0
uniprot id: A0A8C5VYB6
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

30608:TPH2
gene id: 30608:TPH2
uniprot id: A0A8B7EI41
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

30608:NUDT4
gene id: 30608:NUDT4
uniprot id: A0A8B7H384
uniprot id: A0A8C5XRT1
names: Similarity
messages: Belongs to the Nudix hydrolase family. DIPP subfamily.

30608:NT5C3A
gene id: 30608:NT5C3A
uniprot id: A0A8B7EP34
uniprot id: A0A8B7EP38
uniprot id: A0A8C5VAH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

30608:KIN
gene id: 30608:KIN
uniprot id: A0A8B7WWQ8
names: Similarity
messages: Belongs to the KIN17 family.

30608:PPOX
gene id: 30608:PPOX
uniprot id: A0A8B7GLU3
uniprot id: A0A8B7GMD9
uniprot id: A0A8C5UX90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
messages: Mitochondrion inner membrane

30608:EDIL3
gene id: 30608:EDIL3
uniprot id: A0A8B7HRL4
uniprot id: A0A8B7HS99
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:DPRX
gene id: 30608:DPRX
uniprot id: A0A8B7GSL1
names: Subcellular Location Annotation
messages: Nucleus

30608:FARS2
gene id: 30608:FARS2
uniprot id: A0A8B7EF88
uniprot id: A0A8B7EG10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

30608:TFR2
gene id: 30608:TFR2
uniprot id: A0A8B7FZK6
uniprot id: A0A8C5UXU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

30608:MARCH11
gene id: 30608:MARCH11
uniprot id: A0A8B7XCS1
names: Subcellular Location Annotation
messages: Membrane

30608:GLDN
gene id: 30608:GLDN
uniprot id: A0A8B7G9A2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:ZFYVE9
gene id: 30608:ZFYVE9
uniprot id: A0A8B7H5J3
uniprot id: A0A8C6EJP0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Early endosome membrane

30608:MMP23B
gene id: 30608:MMP23B
uniprot id: A0A8B7H630
uniprot id: A0A8B7H641
uniprot id: A0A8B7H8G6
uniprot id: A0A8C5UYK0
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:ACTRT2
gene id: 30608:ACTRT2
uniprot id: A0A8B7H4G0
names: Similarity
messages: Belongs to the actin family.

30608:GPR183
gene id: 30608:GPR183
uniprot id: A0A8B7FQU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:GTF2H4
gene id: 30608:GTF2H4
uniprot id: A0A8B7ECA1
uniprot id: A0A8B7EEI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Nucleus

30608:LOC105875973
gene id: 30608:LOC105875973
uniprot id: A0A8B7GZ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane
messages: Membrane

30608:TM6SF1
gene id: 30608:TM6SF1
uniprot id: A0A8B7G9I5
uniprot id: A0A8C5V7I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TM6SF family.
messages: Membrane

30608:GSTCD
gene id: 30608:GSTCD
uniprot id: A0A8B7HC95
uniprot id: A0A8B7HC98
uniprot id: A0A8B7HCA1
uniprot id: A0A8B7HCA4
uniprot id: A0A8B7HEX8
uniprot id: A0A8C5XQM6
names: Similarity
messages: Belongs to the GSTCD family.

30608:LOC105874392
gene id: 30608:LOC105874392
uniprot id: A0A8B7GR72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PRDM7
gene id: 30608:PRDM7
uniprot id: A0A8B7EDY8
names: Subcellular Location Annotation
messages: Nucleus

30608:MEGF8
gene id: 30608:MEGF8
uniprot id: A0A8B7FWY1
uniprot id: A0A8B7WUH1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:TRAM2
gene id: 30608:TRAM2
uniprot id: A0A8B7G2L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

30608:BSX
gene id: 30608:BSX
uniprot id: A0A8B7I3E4
names: Subcellular Location Annotation
messages: Nucleus

30608:USP3
gene id: 30608:USP3
uniprot id: A0A8C5XLA2
uniprot id: A0A8C5XPI5
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

30608:CDCA5
gene id: 30608:CDCA5
uniprot id: A0A8B7H9W9
uniprot id: A0A8B7H9X0
uniprot id: A0A8B7H9X1
uniprot id: A0A8B7HCN5
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

30608:LOC105872744
gene id: 30608:LOC105872744
uniprot id: A0A8C6ELM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SUB1
gene id: 30608:SUB1
uniprot id: A0A8C5XED8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional coactivator PC4 family.
messages: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
messages: Homodimer. Interacts with CSTF2.
messages: Nucleus

30608:EDEM2
gene id: 30608:EDEM2
uniprot id: A0A8C5Y6A1
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

30608:ISOC1
gene id: 30608:ISOC1
uniprot id: A0A8B7ER20
names: Similarity
messages: Belongs to the isochorismatase family.

30608:UBA2
gene id: 30608:UBA2
uniprot id: A0A8B7H534
uniprot id: A0A8C5V0B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer of SAE1 and UBA2/SAE2. The heterodimer corresponds to the two domains that are encoded on a single polypeptide chain in ubiquitin-activating enzyme E1. Interacts with UBE2I.
messages: Nucleus
messages: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

30608:MGAT4B
gene id: 30608:MGAT4B
uniprot id: A0A8B7I3L1
uniprot id: A0A8B7I3L4
uniprot id: A0A8B7I5L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 54 family.
messages: Golgi apparatus membrane

30608:ZNF768
gene id: 30608:ZNF768
uniprot id: A0A8C5Y8L2
names: Subcellular Location Annotation
messages: Nucleus

30608:EPHA10
gene id: 30608:EPHA10
uniprot id: A0A8C5UYU7
names: Subcellular Location Annotation
messages: Membrane

30608:LOC109729991
gene id: 30608:LOC109729991
uniprot id: A0A8B7WVB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the U1 small nuclear ribonucleoprotein C family.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Nucleus
messages: U1 snRNP is composed of the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.

30608:ANO3
gene id: 30608:ANO3
uniprot id: A0A8B7EXJ8
uniprot id: A0A8B7EXK2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:FAM72A
gene id: 30608:FAM72A
uniprot id: A0A8B7WXW4
uniprot id: A0A8C5XHR2
uniprot id: A0A8C5Y712
names: Similarity
messages: Belongs to the FAM72 family.

30608:ENO1
gene id: 30608:ENO1
uniprot id: A0A8B7I9F8
uniprot id: A0A8B7IAS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

30608:B3GALT4
gene id: 30608:B3GALT4
uniprot id: A0A8B7I7A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:PARL
gene id: 30608:PARL
uniprot id: A0A8B7X2Y7
uniprot id: A0A8C5YKA2
names: Subcellular Location Annotation
messages: Membrane

30608:HIF1A
gene id: 30608:HIF1A
uniprot id: A0A8B7H8V8
uniprot id: A0A8C5VFT7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus speckle

30608:TSSK4
gene id: 30608:TSSK4
uniprot id: A0A8B7FR98
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:SDC3
gene id: 30608:SDC3
uniprot id: A0A8C5XJP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

30608:GLRA3
gene id: 30608:GLRA3
uniprot id: A0A8B7GS80
uniprot id: A0A8B7GSG1
uniprot id: A0A8B7GTW1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

30608:SLC26A6
gene id: 30608:SLC26A6
uniprot id: A0A8B7GTE9
uniprot id: A0A8B7GTN0
uniprot id: A0A8B7GV70
uniprot id: A0A8B7GV75
uniprot id: A0A8B7WKX8
uniprot id: A0A8B7WLN6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:C9H8orf33
gene id: 30608:C9H8orf33
uniprot id: A0A8B7G183
uniprot id: A0A8B7G2K8
names: Similarity
messages: Belongs to the UPF0488 family.

30608:NLRP5
gene id: 30608:NLRP5
uniprot id: A0A8B7WVH2
names: Similarity
messages: Belongs to the NLRP family.

30608:FAM13B
gene id: 30608:FAM13B
uniprot id: A0A8B7F8J5
uniprot id: A0A8B7F8J6
uniprot id: A0A8B7F8J9
uniprot id: A0A8B7F8K4
uniprot id: A0A8B7F8K9
uniprot id: A0A8B7F8L4
uniprot id: A0A8B7F8N6
uniprot id: A0A8B7F8Z4
uniprot id: A0A8B7F906
uniprot id: A0A8C5V2T0
uniprot id: A0A8C5VNE5
names: Similarity
messages: Belongs to the FAM13 family.

30608:LOC105883812
gene id: 30608:LOC105883812
uniprot id: A0A8B7XCC1
names: Similarity
messages: Belongs to the SPATA31 family.

30608:DKKL1
gene id: 30608:DKKL1
uniprot id: A0A8B7FNN2
names: Subcellular Location Annotation
messages: Secreted

30608:HINT2
gene id: 30608:HINT2
uniprot id: A0A8B7GQG4
uniprot id: A0A8B7GQU9
names: Caution
names: Similarity
messages: Belongs to the HINT family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:FARSA
gene id: 30608:FARSA
uniprot id: A0A8B7I7Z9
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.

30608:UBIAD1
gene id: 30608:UBIAD1
uniprot id: A0A8B7I7C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Membrane

30608:CKM
gene id: 30608:CKM
uniprot id: A0A8B7G4S1
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

30608:MZT1
gene id: 30608:MZT1
uniprot id: A0A8B7XE71
names: Function
names: Similarity
messages: Belongs to the MOZART1 family.
messages: Required for gamma-tubulin complex recruitment to the centrosome.

30608:MSMB
gene id: 30608:MSMB
uniprot id: A0A8B7EXG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

30608:POLR2F
gene id: 30608:POLR2F
uniprot id: A0A8C5XPN4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively.
messages: Nucleus

30608:PTP4A3
gene id: 30608:PTP4A3
uniprot id: A0A8B7FFT2
uniprot id: A0A8B7FG07
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

30608:PIWIL4
gene id: 30608:PIWIL4
uniprot id: A0A8B7EKK3
names: Similarity
messages: Belongs to the argonaute family.

30608:LOC105883396
gene id: 30608:LOC105883396
uniprot id: A0A8B7HUZ9
names: Subcellular Location Annotation
messages: Membrane

30608:NUDT19
gene id: 30608:NUDT19
uniprot id: A0A8B7H321
names: Similarity
messages: Belongs to the Nudix hydrolase family.

30608:STXBP5L
gene id: 30608:STXBP5L
uniprot id: A0A8B7X6P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

30608:NUCB1
gene id: 30608:NUCB1
uniprot id: A0A8B7FM32
names: Similarity
messages: Belongs to the nucleobindin family.

30608:TREH
gene id: 30608:TREH
uniprot id: A0A8B7GZB8
uniprot id: A0A8C5XH34
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

30608:MCM9
gene id: 30608:MCM9
uniprot id: A0A8B7EIU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

30608:NDOR1
gene id: 30608:NDOR1
uniprot id: A0A8B7HRV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Interacts with CIAPIN1; as part of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.
messages: NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of CIAPIN1, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. It can also reduce the [2Fe-2S] cluster of CISD1 and activate this protein implicated in Fe/S cluster repair.
messages: perinuclear region

30608:PRDM2
gene id: 30608:PRDM2
uniprot id: A0A8B7G932
uniprot id: A0A8C5Y2G2
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105855229
gene id: 30608:LOC105855229
uniprot id: A0A8B7EB80
uniprot id: A0A8B7EBH2
uniprot id: A0A8B7EDU9
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

30608:TYR
gene id: 30608:TYR
uniprot id: A0A8B7FLA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

30608:PSMB11
gene id: 30608:PSMB11
uniprot id: A0A8B7FI82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

30608:NRXN2
gene id: 30608:NRXN2
uniprot id: A0A8B7H9N6
uniprot id: A0A8B7H9P1
uniprot id: A0A8B7H9P2
uniprot id: A0A8B7H9P3
uniprot id: A0A8B7H9P9
uniprot id: A0A8B7H9Q3
uniprot id: A0A8B7HCG1
uniprot id: A0A8B7HCG6
uniprot id: A0A8B7X2P1
uniprot id: A0A8B7X2P4
uniprot id: A0A8B7X2P6
uniprot id: A0A8B7X2P8
uniprot id: A0A8B7X2Q1
uniprot id: A0A8B7X2Q5
uniprot id: A0A8B7X2Q8
uniprot id: A0A8B7X379
uniprot id: A0A8B7X385
uniprot id: A0A8B7X390
uniprot id: A0A8B7X436
uniprot id: A0A8B7X443
uniprot id: A0A8B7X448
uniprot id: A0A8B7X4F4
uniprot id: A0A8B7X4F9
uniprot id: A0A8B7X4G4
uniprot id: A0A8B7X4G8
uniprot id: A0A8C5ULH9
uniprot id: A0A8C5VNL8
uniprot id: A0A8C6EJM5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:FLOT2
gene id: 30608:FLOT2
uniprot id: A0A8B7EMI0
uniprot id: A0A8B7EMQ0
uniprot id: A0A8B7EPQ8
uniprot id: A0A8C5VKQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Cell membrane
messages: Endosome
messages: Heterooligomeric complex of flotillin-1 and flotillin-2 and caveolin-1 and caveolin-2. Interacts with ECPAS.
messages: May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.
messages: Membrane
messages: Membrane raft
messages: caveola

30608:UCKL1
gene id: 30608:UCKL1
uniprot id: A0A8B7GXW8
uniprot id: A0A8B7GXX0
uniprot id: A0A8B7GY15
uniprot id: A0A8B7GZR7
uniprot id: A0A8C5XJ96
names: Similarity
messages: Belongs to the uridine kinase family.

30608:CORO2B
gene id: 30608:CORO2B
uniprot id: A0A8B7GLB7
uniprot id: A0A8B7GLC7
uniprot id: A0A8B7GLN6
uniprot id: A0A8B7GLY0
names: Similarity
messages: Belongs to the WD repeat coronin family.

30608:SEBOX
gene id: 30608:SEBOX
uniprot id: A0A8B7EP50
names: Subcellular Location Annotation
messages: Nucleus

30608:SELL
gene id: 30608:SELL
uniprot id: A0A8B7HNQ4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selectin/LECAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:GPR87
gene id: 30608:GPR87
uniprot id: A0A8B7HL99
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:PSMA4
gene id: 30608:PSMA4
uniprot id: A0A8B7EJL2
uniprot id: A0A8B7EJL4
uniprot id: A0A8B7EJX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

30608:TRMU
gene id: 30608:TRMU
uniprot id: A0A8B7FTF2
uniprot id: A0A8B7FTK9
uniprot id: A0A8B7FTL4
uniprot id: A0A8B7FTM3
uniprot id: A0A8C5Y547
names: Function
names: Similarity
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.

30608:BTF3
gene id: 30608:BTF3
uniprot id: A0A8B7HMM5
names: Similarity
messages: Belongs to the NAC-beta family.

30608:GBF1
gene id: 30608:GBF1
uniprot id: A0A8B7GPV3
uniprot id: A0A8B7GPV7
uniprot id: A0A8B7GPX3
uniprot id: A0A8B7GQC0
uniprot id: A0A8B7GRF9
names: Subcellular Location Annotation
messages: Golgi apparatus

30608:ANKS1A
gene id: 30608:ANKS1A
uniprot id: A0A8B7F2R4
uniprot id: A0A8B7F2R6
uniprot id: A0A8B7F2R7
uniprot id: A0A8B7F2S0
uniprot id: A0A8B7F2S2
uniprot id: A0A8B7F2S7
uniprot id: A0A8B7F3W2
uniprot id: A0A8B7F3W4
uniprot id: A0A8B7F466
uniprot id: A0A8C5XE97
names: Subcellular Location Annotation
messages: Cytoplasm

30608:TXNIP
gene id: 30608:TXNIP
uniprot id: A0A8C5VP35
names: Similarity
messages: Belongs to the arrestin family.

30608:TMEM38A
gene id: 30608:TMEM38A
uniprot id: A0A8B7FWW5
uniprot id: A0A8B7FXP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

30608:TIMM10B
gene id: 30608:TIMM10B
uniprot id: A0A8C5Y088
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

30608:CAPN10
gene id: 30608:CAPN10
uniprot id: A0A8B7FQJ7
uniprot id: A0A8B7FQK8
uniprot id: A0A8B7FQY0
uniprot id: A0A8B7FRK1
names: Similarity
messages: Belongs to the peptidase C2 family.

30608:SMAD1
gene id: 30608:SMAD1
uniprot id: A0A8B7HNE2
uniprot id: A0A8B7HQW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

30608:CARNMT1
gene id: 30608:CARNMT1
uniprot id: A0A8C5UV07
names: Similarity
messages: Belongs to the carnosine N-methyltransferase family.

30608:COPS7B
gene id: 30608:COPS7B
uniprot id: A0A8B7E9I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

30608:YES1
gene id: 30608:YES1
uniprot id: A0A8B7F1H8
uniprot id: A0A8B7F1I1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

30608:SERPINA11
gene id: 30608:SERPINA11
uniprot id: A0A8B7EI11
uniprot id: A0A8B7EIM0
names: Similarity
messages: Belongs to the serpin family.

30608:ABCG1
gene id: 30608:ABCG1
uniprot id: A0A8B7FAX7
uniprot id: A0A8B7FAY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

30608:PLSCR5
gene id: 30608:PLSCR5
uniprot id: A0A8C5YFX1
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

30608:RSL24D1
gene id: 30608:RSL24D1
uniprot id: A0A8B7HLU2
uniprot id: A0A8B7HPB1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

30608:POLH
gene id: 30608:POLH
uniprot id: A0A8B7GY21
uniprot id: A0A8B7GY67
uniprot id: A0A8B7GZX3
uniprot id: A0A8C5UUK4
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105862117
gene id: 30608:LOC105862117
uniprot id: A0A8B7F729
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PROS1
gene id: 30608:PROS1
uniprot id: A0A8B7WZP9
uniprot id: A0A8C5XDQ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:STUM
gene id: 30608:STUM
uniprot id: A0A8B7FFS5
uniprot id: A0A8C5Y7F6
names: Subcellular Location Annotation
messages: Membrane

30608:HSPA4
gene id: 30608:HSPA4
uniprot id: A0A8B7WSX9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm
messages: Interacts with TJP1/ZO-1.

30608:MARVELD3
gene id: 30608:MARVELD3
uniprot id: A0A8B7EUI1
uniprot id: A0A8C5Y4K5
names: Subcellular Location Annotation
messages: Membrane

30608:SRC
gene id: 30608:SRC
uniprot id: A0A8B7FQE8
uniprot id: A0A8B7FQF2
uniprot id: A0A8C5VCB0
uniprot id: A0A8C6EK56
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

30608:COPS6
gene id: 30608:COPS6
uniprot id: A0A8B7FY76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN6 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.
messages: Cytoplasm
messages: Nucleus

30608:KCNH5
gene id: 30608:KCNH5
uniprot id: A0A8B7H8Y1
uniprot id: A0A8B7X218
names: Subcellular Location Annotation
messages: Membrane

30608:ADNP
gene id: 30608:ADNP
uniprot id: A0A8B7GGI7
names: Subcellular Location Annotation
messages: Nucleus

30608:RFX2
gene id: 30608:RFX2
uniprot id: A0A8B7G4L0
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105856336
gene id: 30608:LOC105856336
uniprot id: A0A8B7EFW2
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

30608:SLC8B1
gene id: 30608:SLC8B1
uniprot id: A0A8B7FH03
uniprot id: A0A8B7FH60
names: Subcellular Location Annotation
messages: Membrane

30608:CENPO
gene id: 30608:CENPO
uniprot id: A0A8C5V798
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-O/MCM21 family.
messages: Nucleus

30608:KDM1A
gene id: 30608:KDM1A
uniprot id: A0A8B7WNY4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavin monoamine oxidase family.
messages: Histone demethylase that can demethylate both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes. Alone, it is unable to demethylate H3K4me on nucleosomes and requires the presence of RCOR1/CoREST to achieve such activity.
messages: Nucleus
messages: The SWIRM domain may act as an anchor site for a histone tail.

30608:SETDB1
gene id: 30608:SETDB1
uniprot id: A0A8B7GJJ1
uniprot id: A0A8B7GKA5
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

30608:METTL6
gene id: 30608:METTL6
uniprot id: A0A8B7GI66
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.

30608:PPP4R3B
gene id: 30608:PPP4R3B
uniprot id: A0A8B7X3T4
names: Similarity
messages: Belongs to the SMEK family.

30608:ASAH2
gene id: 30608:ASAH2
uniprot id: A0A8B7G7M3
uniprot id: A0A8B7G8B3
uniprot id: A0A8B7WLJ3
names: Similarity
messages: Belongs to the neutral ceramidase family.

30608:LOC105859125
gene id: 30608:LOC105859125
uniprot id: A0A8B7X273
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction

30608:THBS1
gene id: 30608:THBS1
uniprot id: A0A8C6EGQ8
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:EFHC2
gene id: 30608:EFHC2
uniprot id: A0A8B7WYW6
names: Subcellular Location Annotation
messages: cilium axoneme

30608:CFAP206
gene id: 30608:CFAP206
uniprot id: A0A8B7FDV5
uniprot id: A0A8B7FE12
uniprot id: A0A8C5XBI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP206 family.
messages: cilium axoneme

30608:TMTC1
gene id: 30608:TMTC1
uniprot id: A0A8B7F6M5
uniprot id: A0A8B7F6S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

30608:TNFAIP2
gene id: 30608:TNFAIP2
uniprot id: A0A8B7F3L6
names: Similarity
messages: Belongs to the SEC6 family.

30608:INTS2
gene id: 30608:INTS2
uniprot id: A0A8B7GX97
uniprot id: A0A8B7GZA8
uniprot id: A0A8C5VCR5
names: Similarity
messages: Belongs to the Integrator subunit 2 family.

30608:XPO7
gene id: 30608:XPO7
uniprot id: A0A8B7EJ48
uniprot id: A0A8B7EJH0
uniprot id: A0A8C5XQK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

30608:ZDHHC5
gene id: 30608:ZDHHC5
uniprot id: A0A8B7FB61
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

30608:LOC105859514
gene id: 30608:LOC105859514
uniprot id: A0A8B7EU97
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:FAT2
gene id: 30608:FAT2
uniprot id: A0A8C5Y4M6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:BTF3L4
gene id: 30608:BTF3L4
uniprot id: A0A8B7H5I6
uniprot id: A0A8B7H7W0
names: Similarity
messages: Belongs to the NAC-beta family.

30608:ABCC8
gene id: 30608:ABCC8
uniprot id: A0A8B7HG82
uniprot id: A0A8B7HG87
uniprot id: A0A8B7HGB6
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with KCNJ11.
messages: Membrane

30608:HTRA2
gene id: 30608:HTRA2
uniprot id: A0A8B7I2J3
names: Similarity
messages: Belongs to the peptidase S1C family.

30608:MESDC2
gene id: 30608:MESDC2
uniprot id: A0A8C5XXL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MESD family.
messages: Endoplasmic reticulum

30608:LCK
gene id: 30608:LCK
uniprot id: A0A8B7GDW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

30608:TFRC
gene id: 30608:TFRC
uniprot id: A0A8B7X465
uniprot id: A0A8B7X4R0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Acts as a lipid sensor that regulates mitochondrial fusion by regulating activation of the JNK pathway.
messages: Homodimer; disulfide-linked.
messages: Melanosome
messages: Membrane
messages: Stearoylated.

30608:LOC109731114
gene id: 30608:LOC109731114
uniprot id: A0A8B7XA34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

30608:FMN1
gene id: 30608:FMN1
uniprot id: A0A8B7GG88
uniprot id: A0A8B7GH34
uniprot id: A0A8B7X1Z0
uniprot id: A0A8C6EID3
names: Similarity
messages: Belongs to the formin homology family. Cappuccino subfamily.

30608:LOC105858676
gene id: 30608:LOC105858676
uniprot id: A0A8C5V9L5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

30608:LOC105864774
gene id: 30608:LOC105864774
uniprot id: A0A8B7FIG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TMEM132A
gene id: 30608:TMEM132A
uniprot id: A0A8B7HAP7
uniprot id: A0A8B7HAP9
uniprot id: A0A8B7HAQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

30608:NOSTRIN
gene id: 30608:NOSTRIN
uniprot id: A0A8B7HIZ0
names: Subcellular Location Annotation
messages: cytoskeleton

30608:LOC105862829
gene id: 30608:LOC105862829
uniprot id: A0A8B7X7F7
uniprot id: A0A8B7X944
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with TOGARAM1, CCDC66, CEP104, CSPP1 and CEP290.
messages: centriole
messages: cilium
messages: cilium basal body

30608:LOC105865443
gene id: 30608:LOC105865443
uniprot id: A0A8B7X5D4
names: Similarity
messages: Belongs to the KHDC1 family.

30608:LOC105866554
gene id: 30608:LOC105866554
uniprot id: A0A8B7FS32
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

30608:FBN1
gene id: 30608:FBN1
uniprot id: A0A8B7X1Z7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibrillin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:PDE4B
gene id: 30608:PDE4B
uniprot id: A0A8B7GIB7
uniprot id: A0A8B7GIC5
uniprot id: A0A8B7GIP7
uniprot id: A0A8B7GJC2
uniprot id: A0A8B7X9R9
uniprot id: A0A8C5XR91
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

30608:SMARCD1
gene id: 30608:SMARCD1
uniprot id: A0A8B7G5B6
uniprot id: A0A8B7G5H0
uniprot id: A0A8B7G6N2
names: Similarity
messages: Belongs to the SMARCD family.

30608:CACNA2D2
gene id: 30608:CACNA2D2
uniprot id: A0A8B7GTV2
uniprot id: A0A8B7GTV4
uniprot id: A0A8B7GU03
uniprot id: A0A8B7GU29
uniprot id: A0A8B7WKY0
uniprot id: A0A8B7WKY6
uniprot id: A0A8B7WL01
uniprot id: A0A8B7WL06
uniprot id: A0A8B7WL25
uniprot id: A0A8B7WLR7
uniprot id: A0A8B7WLS3
uniprot id: A0A8C5Y6R1
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

30608:NAGLU
gene id: 30608:NAGLU
uniprot id: A0A8B7EVW2
names: Subcellular Location Annotation
messages: Lysosome

30608:LOC105869479
gene id: 30608:LOC105869479
uniprot id: A0A8B7G4J0
uniprot id: A0A8C5XN39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

30608:CDC42BPA
gene id: 30608:CDC42BPA
uniprot id: A0A8B7FEC8
uniprot id: A0A8B7FED2
uniprot id: A0A8B7FED8
uniprot id: A0A8B7FEE1
uniprot id: A0A8B7FEE3
uniprot id: A0A8B7FEE8
uniprot id: A0A8B7FEF3
uniprot id: A0A8B7FEF4
uniprot id: A0A8B7FEF8
uniprot id: A0A8B7FEF9
uniprot id: A0A8B7FEG3
uniprot id: A0A8B7FEL9
uniprot id: A0A8B7FEM4
uniprot id: A0A8B7FEM9
uniprot id: A0A8B7FFD3
uniprot id: A0A8B7FFD8
uniprot id: A0A8B7FFE3
uniprot id: A0A8C5Y9L3
uniprot id: A0A8C5YC38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: Cytoplasm
messages: lamellipodium

30608:SORCS2
gene id: 30608:SORCS2
uniprot id: A0A8B7WQL9
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

30608:ADCK2
gene id: 30608:ADCK2
uniprot id: A0A8B7GKH4
uniprot id: A0A8B7GKU1
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

30608:HM13
gene id: 30608:HM13
uniprot id: A0A8B7FQ43
uniprot id: A0A8C5VXK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

30608:IL1B
gene id: 30608:IL1B
uniprot id: A0A8B7ESZ0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-1 family.
messages: IL1B production occurs in 2 steps, each being controlled by different stimuli. First, inflammatory signals, such as LPS, stimulate the synthesis and promote the accumulation of cytosolic stores of pro-IL1B (priming). Then additional signals are required for inflammasome assembly, leading to CASP1 activation, pro-IL1B processing and eventually secretion of the active cytokine. IL1B processing and secretion are temporarily associated.
messages: Lysosome
messages: Monomer. Interacts with MEFV.
messages: Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
messages: Secreted
messages: cytosol
messages: extracellular exosome

30608:ARMC1
gene id: 30608:ARMC1
uniprot id: A0A8B7EDW6
uniprot id: A0A8B7EEK0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

30608:DTYMK
gene id: 30608:DTYMK
uniprot id: A0A8B7FQE7
names: Similarity
messages: Belongs to the thymidylate kinase family.

30608:RPAP1
gene id: 30608:RPAP1
uniprot id: A0A8B7GGM9
uniprot id: A0A8B7GHI0
names: Similarity
messages: Belongs to the RPAP1 family.

30608:UCP1
gene id: 30608:UCP1
uniprot id: A0A8B7HNI5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: May undergo ubiquitin-mediated proteasomal degradation.
messages: Membrane
messages: Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates in non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance. Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane. However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in an apparent transport of protons activated by LCFAs. Thereby, dissipates the mitochondrial proton gradient and converts the energy of substrate oxydation into heat instead of ATP. Regulates the production of reactive oxygen species/ROS by mitochondria.
messages: Mitochondrion inner membrane

30608:LOC105884212
gene id: 30608:LOC105884212
uniprot id: A0A8B7HYR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:LOC105885445
gene id: 30608:LOC105885445
uniprot id: A0A8B7WVH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: nucleolus

30608:KRT74
gene id: 30608:KRT74
uniprot id: A0A8B7G8V7
names: Similarity
messages: Belongs to the intermediate filament family.

30608:LOC105855655
gene id: 30608:LOC105855655
uniprot id: A0A8B7ECR5
uniprot id: A0A8B7EFE1
names: Similarity
messages: Belongs to the DNAJC25 family.

30608:LOC105868221
gene id: 30608:LOC105868221
uniprot id: A0A8B7WPC3
uniprot id: A0A8B7WPC5
uniprot id: A0A8B7WPG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

30608:PURB
gene id: 30608:PURB
uniprot id: A0A8B7G9H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

30608:PTPRJ
gene id: 30608:PTPRJ
uniprot id: A0A8B7X3G9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.

30608:LOC105864167
gene id: 30608:LOC105864167
uniprot id: A0A8B7XDC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative pheromone receptor.

30608:EXOC2
gene id: 30608:EXOC2
uniprot id: A0A8B7GLQ4
uniprot id: A0A8B7GM18
uniprot id: A0A8B7GM99
uniprot id: A0A8C5YAI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SEC5 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: Component of the exocyst complex.

30608:KCTD13
gene id: 30608:KCTD13
uniprot id: A0A8B7GBE6
uniprot id: A0A8C6EK73
names: Similarity
messages: Belongs to the BACURD family.

30608:ST8SIA3
gene id: 30608:ST8SIA3
uniprot id: A0A8C5UND2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

30608:ZNF711
gene id: 30608:ZNF711
uniprot id: A0A8B7I406
uniprot id: A0A8B7I426
uniprot id: A0A8B7I732
names: Subcellular Location Annotation
messages: Nucleus

30608:MDM4
gene id: 30608:MDM4
uniprot id: A0A8B7FZZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain.
messages: Nucleus

30608:EID2B
gene id: 30608:EID2B
uniprot id: A0A8B7H357
names: Subcellular Location Annotation
messages: Nucleus

30608:OAF
gene id: 30608:OAF
uniprot id: A0A8B7X5L9
names: Similarity
messages: Belongs to the OAF family.

30608:KYNU
gene id: 30608:KYNU
uniprot id: A0A8B7XAP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:SLC5A9
gene id: 30608:SLC5A9
uniprot id: A0A8B7H594
uniprot id: A0A8B7H597
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

30608:INTS7
gene id: 30608:INTS7
uniprot id: A0A8B7HIH0
uniprot id: A0A8C5VLZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 7 family.
messages: Nucleus

30608:LOC105884118
gene id: 30608:LOC105884118
uniprot id: A0A8B7HYH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SLC1A3
gene id: 30608:SLC1A3
uniprot id: A0A8B7EEP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

30608:CCT8
gene id: 30608:CCT8
uniprot id: A0A8B7GC32
uniprot id: A0A8C5VP32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: cilium basal body

30608:LOC105878844
gene id: 30608:LOC105878844
uniprot id: A0A8B7HBB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:DNASE1
gene id: 30608:DNASE1
uniprot id: A0A8B7EVC5
names: Similarity
messages: Belongs to the DNase I family.

30608:LYZL6
gene id: 30608:LYZL6
uniprot id: A0A8B7HW18
uniprot id: A0A8B7HW31
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

30608:TRAPPC2
gene id: 30608:TRAPPC2
uniprot id: A0A8C5XGW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

30608:KCNC4
gene id: 30608:KCNC4
uniprot id: A0A8B7FFM9
uniprot id: A0A8B7FFP2
uniprot id: A0A8B7WV76
names: Subcellular Location Annotation
messages: Membrane

30608:RAD9A
gene id: 30608:RAD9A
uniprot id: A0A8C5W617
names: Similarity
messages: Belongs to the rad9 family.

30608:FZD6
gene id: 30608:FZD6
uniprot id: A0A8B7HPN6
uniprot id: A0A8B7XC10
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:LYRM9
gene id: 30608:LYRM9
uniprot id: A0A8C5W187
names: Similarity
messages: Belongs to the complex I LYR family. LYRM9 subfamily.

30608:GEM
gene id: 30608:GEM
uniprot id: A0A8B7GXI6
uniprot id: A0A8B7GXJ2
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

30608:PSKH1
gene id: 30608:PSKH1
uniprot id: A0A8B7ES17
uniprot id: A0A8C5W1G8
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:GDPD2
gene id: 30608:GDPD2
uniprot id: A0A8B7EBX7
uniprot id: A0A8C5VT14
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

30608:IREB2
gene id: 30608:IREB2
uniprot id: A0A8C5VB34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Cytoplasm

30608:FAM189B
gene id: 30608:FAM189B
uniprot id: A0A8B7GKB6
uniprot id: A0A8C5V8Z2
uniprot id: A0A8C5VSL2
names: Similarity
messages: Belongs to the ENTREP family.

30608:IRAK4
gene id: 30608:IRAK4
uniprot id: A0A8B7F5H4
uniprot id: A0A8B7X6C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with MYD88 and IRAK2 to form a ternary complex called the Myddosome.
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Cytoplasm
messages: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens.

30608:XKR9
gene id: 30608:XKR9
uniprot id: A0A8B7GSN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

30608:TMC8
gene id: 30608:TMC8
uniprot id: A0A8B7WP72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

30608:FUT4
gene id: 30608:FUT4
uniprot id: A0A8B7EK87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Membrane

30608:ANXA11
gene id: 30608:ANXA11
uniprot id: A0A8C5VDX6
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

30608:LOC105859216
gene id: 30608:LOC105859216
uniprot id: A0A8B7ET14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:FAM219B
gene id: 30608:FAM219B
uniprot id: A0A8B7E9W8
uniprot id: A0A8B7EAD6
names: Similarity
messages: Belongs to the FAM219 family.

30608:CACNA1A
gene id: 30608:CACNA1A
uniprot id: A0A8B7WVH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q-type calcium currents.

30608:OPALIN
gene id: 30608:OPALIN
uniprot id: A0A8B7GIJ9
uniprot id: A0A8B7GIK0
uniprot id: A0A8B7GIK4
uniprot id: A0A8B7GIV6
uniprot id: A0A8B7GIY4
uniprot id: A0A8B7GIY8
uniprot id: A0A8B7GJK0
uniprot id: A4PCE1
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Central nervous system-specific myelin protein that increase myelin genes expression during oligodendrocyte differentiation. Promotes oligodendrocyte terminal differentiation.
messages: Membrane

30608:IRX1
gene id: 30608:IRX1
uniprot id: A0A8B7I1F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

30608:LOC105869279
gene id: 30608:LOC105869279
uniprot id: A0A8B7WWS2
uniprot id: A0A8B7WXK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

30608:APMAP
gene id: 30608:APMAP
uniprot id: A0A8C5UMM2
names: Similarity
messages: Belongs to the strictosidine synthase family.

30608:CLDN6
gene id: 30608:CLDN6
uniprot id: A0A8B7EUW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

30608:LOC105885840
gene id: 30608:LOC105885840
uniprot id: A0A8B7XDS1
names: Similarity
messages: Belongs to the Rab GDI family.

30608:GAD1
gene id: 30608:GAD1
uniprot id: A0A8B7HJ38
uniprot id: A0A8B7HLM9
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

30608:AMBN
gene id: 30608:AMBN
uniprot id: A0A8B7HTJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ameloblastin family.
messages: Involved in the mineralization and structural organization of enamel.
messages: extracellular matrix

30608:IRF5
gene id: 30608:IRF5
uniprot id: A0A8B7I1W0
uniprot id: A0A8B7I3X2
uniprot id: A0A8C5VPD7
names: Subcellular Location Annotation
messages: Nucleus

30608:CNKSR1
gene id: 30608:CNKSR1
uniprot id: A0A8C5V5F8
names: Similarity
messages: Belongs to the CNKSR family.

30608:DSG1
gene id: 30608:DSG1
uniprot id: A0A8B7HKJ0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

30608:SLC46A1
gene id: 30608:SLC46A1
uniprot id: A0A8B7EMZ8
uniprot id: A0A8B7EN01
uniprot id: A0A8B7EN03
uniprot id: A0A8B7EN65
uniprot id: A0A8B7EPH3
uniprot id: A0A8B7EQ76
names: Subcellular Location Annotation
messages: Membrane

30608:PARD6G
gene id: 30608:PARD6G
uniprot id: A0A8B7I195
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

30608:PPP2R2A
gene id: 30608:PPP2R2A
uniprot id: A0A8B7WSM8
uniprot id: A0A8B7WSQ9
uniprot id: A0A8B7WU60
uniprot id: A0A8C5XGC4
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

30608:LOC105855573
gene id: 30608:LOC105855573
uniprot id: A0A8B7WZ03
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

30608:TFCP2L1
gene id: 30608:TFCP2L1
uniprot id: A0A8B7F671
uniprot id: A0A8C5Y9L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

30608:LOC105880290
gene id: 30608:LOC105880290
uniprot id: A0A8B7HHG4
names: Similarity
messages: Belongs to the cytochrome b5 family.

30608:KCNK12
gene id: 30608:KCNK12
uniprot id: A0A8B7FRC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

30608:CENPA
gene id: 30608:CENPA
uniprot id: A0A8B7X8V9
names: Similarity
messages: Belongs to the histone H3 family.

30608:NPC1L1
gene id: 30608:NPC1L1
uniprot id: A0A8B7G9V2
uniprot id: A0A8B7XEQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

30608:STK11
gene id: 30608:STK11
uniprot id: A0A8B7F0E3
uniprot id: A0A8B7F0E4
uniprot id: A0A8B7F0F0
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. LKB1 subfamily.

30608:LOC105873636
gene id: 30608:LOC105873636
uniprot id: A0A8B7GNL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MPP4
gene id: 30608:MPP4
uniprot id: A0A8B7X7U7
uniprot id: A0A8B7X7V1
uniprot id: A0A8B7X7V7
uniprot id: A0A8B7X8I4
uniprot id: A0A8B7X9I5
uniprot id: A0A8B7X9J0
uniprot id: A0A8B7X9J5
uniprot id: A0A8B7X9V2
uniprot id: A0A8B7X9V5
names: Similarity
messages: Belongs to the MAGUK family.

30608:CREG2
gene id: 30608:CREG2
uniprot id: A0A8B7EPG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

30608:ADGRL2
gene id: 30608:ADGRL2
uniprot id: A0A8B7F689
uniprot id: A0A8B7F693
uniprot id: A0A8B7F695
uniprot id: A0A8B7F698
uniprot id: A0A8B7F699
uniprot id: A0A8B7F6A0
uniprot id: A0A8B7F6A3
uniprot id: A0A8B7F6A4
uniprot id: A0A8B7F6A9
uniprot id: A0A8B7F6B4
uniprot id: A0A8B7F6C2
uniprot id: A0A8B7F6D9
uniprot id: A0A8B7F6E5
uniprot id: A0A8B7F6F0
uniprot id: A0A8B7WS86
uniprot id: A0A8B7WS92
uniprot id: A0A8B7WS97
uniprot id: A0A8B7WSA5
uniprot id: A0A8B7WSB1
uniprot id: A0A8B7WSC3
uniprot id: A0A8B7WSC4
uniprot id: A0A8B7WSE7
uniprot id: A0A8B7WTR0
uniprot id: A0A8C5VDQ7
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105864764
gene id: 30608:LOC105864764
uniprot id: A0A8B7FIN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Odorant receptor.

30608:SLC35B2
gene id: 30608:SLC35B2
uniprot id: A0A8B7EUD0
uniprot id: A0A8B7EUD6
uniprot id: A0A8B7EWC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

30608:SLC2A13
gene id: 30608:SLC2A13
uniprot id: A0A8C5XNA4
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

30608:CCK
gene id: 30608:CCK
uniprot id: A0A8C5YIN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Secreted

30608:MAN2B2
gene id: 30608:MAN2B2
uniprot id: A0A8B7WQP8
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

30608:LOC105856759
gene id: 30608:LOC105856759
uniprot id: A0A8B7EHK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MGAM2
gene id: 30608:MGAM2
uniprot id: A0A8B7XBV9
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:DHCR7
gene id: 30608:DHCR7
uniprot id: A0A8B7FV60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

30608:ULK1
gene id: 30608:ULK1
uniprot id: A0A8C5W8M9
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
messages: Serine/threonine-protein kinase involved in autophagy in response to starvation.

30608:GATA3
gene id: 30608:GATA3
uniprot id: A0A8B7ER69
uniprot id: A0A8B7WY78
uniprot id: A0A8C5W804
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105884153
gene id: 30608:LOC105884153
uniprot id: A0A8B7I190
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

30608:ETHE1
gene id: 30608:ETHE1
uniprot id: A0A8B7G3J1
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

30608:LOC105864538
gene id: 30608:LOC105864538
uniprot id: A0A8B7FHG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:VAMP3
gene id: 30608:VAMP3
uniprot id: A0A8B7I7J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

30608:MRPL53
gene id: 30608:MRPL53
uniprot id: A0A8B7I0H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

30608:IFRD2
gene id: 30608:IFRD2
uniprot id: A0A8B7GTT8
names: Similarity
messages: Belongs to the IFRD family.

30608:TRMT11
gene id: 30608:TRMT11
uniprot id: A0A8B7H8J2
uniprot id: A0A8B7H8J9
uniprot id: A0A8C5W1N5
names: Function
names: Subunit
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.
messages: Interacts with TRMT112.

30608:LOC105878455
gene id: 30608:LOC105878455
uniprot id: A0A8B7H9F4
names: Subcellular Location Annotation
messages: Membrane

30608:STK3
gene id: 30608:STK3
uniprot id: A0A8B7G5F3
uniprot id: A0A8C5VN44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Nucleus

30608:ATP5J2
gene id: 30608:ATP5J2
uniprot id: A0A8B7FY98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

30608:C9
gene id: 30608:C9
uniprot id: A0A8C5UUE6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:CLK2
gene id: 30608:CLK2
uniprot id: A0A8B7GK14
uniprot id: A0A8B7GKC7
uniprot id: A0A8B7GL70
uniprot id: A0A8B7GL75
uniprot id: A0A8B7WZU7
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:GABPA
gene id: 30608:GABPA
uniprot id: A0A8C5XC97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

30608:IPO5
gene id: 30608:IPO5
uniprot id: A0A8B7FUG4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:LAMC1
gene id: 30608:LAMC1
uniprot id: A0A8C5VBB7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

30608:HAP1
gene id: 30608:HAP1
uniprot id: A0A8B7GET8
uniprot id: A0A8B7GFK2
uniprot id: A0A8B7WNI8
names: Subcellular Location Annotation
messages: Early endosome
messages: Mitochondrion

30608:EPN2
gene id: 30608:EPN2
uniprot id: A0A8B7F6G1
uniprot id: A0A8C5XNH5
names: Similarity
messages: Belongs to the epsin family.

30608:INTS13
gene id: 30608:INTS13
uniprot id: A0A8B7EJW8
uniprot id: A0A8B7EL47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the asunder family.
messages: Cytoplasm
messages: Nucleus

30608:LOC105869699
gene id: 30608:LOC105869699
uniprot id: A0A8B7G5K8
names: Subcellular Location Annotation
messages: Membrane

30608:BEST2
gene id: 30608:BEST2
uniprot id: A0A8B7I4U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.
messages: Cell membrane
messages: Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
messages: Membrane

30608:LOC105883464
gene id: 30608:LOC105883464
uniprot id: A0A8B7HXH6
names: Subcellular Location Annotation
messages: Membrane

30608:KMO
gene id: 30608:KMO
uniprot id: A0A8C5Y977
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.
messages: Mitochondrion outer membrane

30608:GCAT
gene id: 30608:GCAT
uniprot id: A0A8B7EQH2
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

30608:KMT2A
gene id: 30608:KMT2A
uniprot id: A0A8B7X3K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
messages: Nucleus

30608:NBL1
gene id: 30608:NBL1
uniprot id: A0A8C5V9W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

30608:LOC105861217
gene id: 30608:LOC105861217
uniprot id: A0A8B7F2C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
messages: Belongs to the GAMAD family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer.
messages: cytoskeleton

30608:MYCL
gene id: 30608:MYCL
uniprot id: A0A8B7EB21
uniprot id: A0A8B7ED44
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

30608:B3GNT5
gene id: 30608:B3GNT5
uniprot id: A0A8B7X2X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:MAGI2
gene id: 30608:MAGI2
uniprot id: A0A8B7XD63
names: Subcellular Location Annotation
messages: Membrane

30608:STAM2
gene id: 30608:STAM2
uniprot id: A0A8B7XAG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane
messages: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.

30608:CSRNP1
gene id: 30608:CSRNP1
uniprot id: A0A8B7ET12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

30608:PGM2L1
gene id: 30608:PGM2L1
uniprot id: A0A8B7X509
names: Similarity
messages: Belongs to the phosphohexose mutase family.

30608:FDFT1
gene id: 30608:FDFT1
uniprot id: A0A8B7FIM1
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

30608:HSPE1
gene id: 30608:HSPE1
uniprot id: A0A8B7H7E2
uniprot id: A0A8B7H7F4
uniprot id: A0A8B7H9X7
names: Similarity
messages: Belongs to the GroES chaperonin family.
messages: Belongs to the MOB1/phocein family.

30608:LOC105878756
gene id: 30608:LOC105878756
uniprot id: A0A8B7HB27
names: Similarity
messages: Belongs to the TIP41 family.

30608:CD63
gene id: 30608:CD63
uniprot id: A0A8B7FK48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Cell membrane
messages: Cell surface
messages: Endosome membrane
messages: Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.
messages: Late endosome membrane
messages: Lysosome membrane
messages: Melanosome
messages: Membrane
messages: extracellular exosome
messages: multivesicular body

30608:ERG
gene id: 30608:ERG
uniprot id: A0A8B7WYF4
uniprot id: A0A8C5YFB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

30608:ELMO1
gene id: 30608:ELMO1
uniprot id: A0A8B7H8Q1
uniprot id: A0A8B7H8Q7
uniprot id: A0A8B7H8R3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

30608:LOC105856111
gene id: 30608:LOC105856111
uniprot id: A0A8B7X2E6
names: Similarity
messages: Belongs to the DEAD box helicase family.

30608:SLC15A1
gene id: 30608:SLC15A1
uniprot id: A0A8B7FRF0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Interacts (via extracellular domain region) with trypsin.
messages: Membrane

30608:TMEM163
gene id: 30608:TMEM163
uniprot id: A0A8B7XAA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM163 family.
messages: Membrane
messages: synaptic vesicle membrane

30608:RPS4X
gene id: 30608:RPS4X
uniprot id: A0A8C5V739
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

30608:LOC105865975
gene id: 30608:LOC105865975
uniprot id: A0A8B7FNU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm

30608:CAV3
gene id: 30608:CAV3
uniprot id: A0A8C5VTN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

30608:NEUROD1
gene id: 30608:NEUROD1
uniprot id: A0A8B7HVI8
names: Subcellular Location Annotation
messages: Nucleus

30608:IQSEC3
gene id: 30608:IQSEC3
uniprot id: A0A8B7F7H0
uniprot id: A0A8B7F7H1
uniprot id: A0A8B7F7H6
uniprot id: A0A8B7F7I0
uniprot id: A0A8B7F7K5
uniprot id: A0A8B7F7L4
uniprot id: A0A8B7F7Q8
uniprot id: A0A8B7F7R3
uniprot id: A0A8C5XEP1
names: Similarity
messages: Belongs to the BRAG family.

30608:ADGRG4
gene id: 30608:ADGRG4
uniprot id: A0A8B7X0G3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:DDIT4L
gene id: 30608:DDIT4L
uniprot id: A0A8B7EH15
uniprot id: A0A8B7EHG4
uniprot id: A0A8B7EJG7
names: Similarity
messages: Belongs to the DDIT4 family.

30608:MMP12
gene id: 30608:MMP12
uniprot id: A0A8C5US46
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

30608:VCL
gene id: 30608:VCL
uniprot id: A0A8B7G0D4
uniprot id: A0A8B7G184
uniprot id: A0A8B7G1M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction
messages: podosome

30608:SDE2
gene id: 30608:SDE2
uniprot id: A0A8B7FE88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDE2 family.
messages: Cytoplasm
messages: Nucleus

30608:SLC2A7
gene id: 30608:SLC2A7
uniprot id: A0A8B7X0W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell membrane

30608:STN1
gene id: 30608:STN1
uniprot id: A0A8B7GS86
uniprot id: A0A8B7GTM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the STN1 family.
messages: Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
messages: Component of the CST complex.
messages: Nucleus
messages: telomere

30608:GPR182
gene id: 30608:GPR182
uniprot id: A0A8C5UPM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105866560
gene id: 30608:LOC105866560
uniprot id: A0A8B7FS32
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

30608:SYNGR1
gene id: 30608:SYNGR1
uniprot id: A0A8B7EQ24
uniprot id: A0A8B7ERQ6
uniprot id: A0A8C5VWZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

30608:LOC105873921
gene id: 30608:LOC105873921
uniprot id: A0A8B7GNL7
uniprot id: A0A8B7GP55
uniprot id: A0A8B7GQ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HDGF family.
messages: Nucleus

30608:PMP22
gene id: 30608:PMP22
uniprot id: A0A8B7F6I0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Might be involved in growth regulation, and in myelinization in the peripheral nervous system.

30608:HNRNPR
gene id: 30608:HNRNPR
uniprot id: A0A8B7FD15
uniprot id: A0A8B7FD77
uniprot id: A0A8B7FDU6
uniprot id: A0A8B7WMN9
names: Subcellular Location Annotation
messages: Cytoplasm

30608:PRDM12
gene id: 30608:PRDM12
uniprot id: A0A8C5V3W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Involved in the positive regulation of histone H3-K9 dimethylation.
messages: Nucleus

30608:TMCC3
gene id: 30608:TMCC3
uniprot id: A0A8B7H3A6
uniprot id: A0A8B7H3G1
uniprot id: A0A8B7H5H1
uniprot id: A0A8B7X8U4
names: Similarity
messages: Belongs to the TEX28 family.

30608:LOC105858301
gene id: 30608:LOC105858301
uniprot id: A0A8C5Y4W5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:CARM1
gene id: 30608:CARM1
uniprot id: A0A8B7WWD7
names: Subcellular Location Annotation
messages: Nucleus

30608:SPTLC2
gene id: 30608:SPTLC2
uniprot id: A0A8B7ETN3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

30608:IBSP
gene id: 30608:IBSP
uniprot id: A0A8B7H0E9
names: Function
names: Subcellular Location Annotation
messages: Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.
messages: Secreted

30608:ANAPC1
gene id: 30608:ANAPC1
uniprot id: A0A8B7EUQ9
uniprot id: A0A8B7EUW7
names: Similarity
messages: Belongs to the APC1 family.

30608:UBE2E3
gene id: 30608:UBE2E3
uniprot id: A0A8C6EKC5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:VANGL2
gene id: 30608:VANGL2
uniprot id: A0A8B7WZ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

30608:GPD2
gene id: 30608:GPD2
uniprot id: A0A8B7ESP6
uniprot id: A0A8B7ESQ1
names: Function
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.

30608:ITM2A
gene id: 30608:ITM2A
uniprot id: A0A8C5XLG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

30608:GALNT2
gene id: 30608:GALNT2
uniprot id: A0A8B7EHD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

30608:PAQR4
gene id: 30608:PAQR4
uniprot id: A0A8C5YF69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

30608:TMEM144
gene id: 30608:TMEM144
uniprot id: A0A8B7HMX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM144 family.
messages: Membrane

30608:ILF3
gene id: 30608:ILF3
uniprot id: A0A8B7I595
uniprot id: A0A8B7I5A0
uniprot id: A0A8B7I5C3
uniprot id: A0A8B7I7A1
uniprot id: A0A8B7I8F4
uniprot id: A0A8C5VN23
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:G6PD
gene id: 30608:G6PD
uniprot id: A0A8B7FWA2
uniprot id: A0A8B7FWA6
uniprot id: A0A8C5V8L2
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.

30608:USP14
gene id: 30608:USP14
uniprot id: A0A8B7F3H8
uniprot id: A0A8C5YCG1
uniprot id: A0A8C6EEZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase C19 family.
messages: Belongs to the peptidase C19 family. USP14/UBP6 subfamily.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Homodimer (Potential). Associates with the 26S proteasome. Interacts with FANCC, CXCR4 and ERN1. Interacts with TRIM14; this interaction recruits USP14 to cleave ubiquitin chains of CGAS.

30608:LOC105861333
gene id: 30608:LOC105861333
uniprot id: A0A8B7F2Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105883364
gene id: 30608:LOC105883364
uniprot id: A0A8B7HUX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ANAPC5
gene id: 30608:ANAPC5
uniprot id: A0A8B7WTE2
uniprot id: A0A8B7WTE3
uniprot id: A0A8B7WTK7
uniprot id: A0A8B7WTR2
uniprot id: A0A8C5XJL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC5 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: spindle

30608:DOK1
gene id: 30608:DOK1
uniprot id: A0A8C5Y8R2
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

30608:LRWD1
gene id: 30608:LRWD1
uniprot id: A0A8B7FYC9
uniprot id: A0A8B7WPE1
uniprot id: A0A8B7WQR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRWD1 family.
messages: centrosome
messages: kinetochore
messages: telomere

30608:TMEM176A
gene id: 30608:TMEM176A
uniprot id: A0A8B7HU96
names: Similarity
messages: Belongs to the TMEM176 family.

30608:ENDOG
gene id: 30608:ENDOG
uniprot id: A0A8C5V6G6
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

30608:PLA2G2C
gene id: 30608:PLA2G2C
uniprot id: A0A8B7HY22
uniprot id: A0A8B7HY34
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

30608:GRK2
gene id: 30608:GRK2
uniprot id: A0A8B7FV54
uniprot id: A0A8B7FV61
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

30608:LOC105870466
gene id: 30608:LOC105870466
uniprot id: A0A8C5UTK5
names: Similarity
messages: Belongs to the intermediate filament family.

30608:PSMD2
gene id: 30608:PSMD2
uniprot id: A0A8C5YIC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S2 family.
messages: Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

30608:MAU2
gene id: 30608:MAU2
uniprot id: A0A8B7ER32
uniprot id: A0A8B7ERM1
uniprot id: A0A8C5YAZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC4/mau-2 family.
messages: nucleoplasm

30608:ADAMTS7
gene id: 30608:ADAMTS7
uniprot id: A0A8B7EJG1
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:LOC105861304
gene id: 30608:LOC105861304
uniprot id: A0A8B7F2M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105873358
gene id: 30608:LOC105873358
uniprot id: A0A8B7GM55
names: Subcellular Location Annotation
messages: Membrane

30608:CAPN12
gene id: 30608:CAPN12
uniprot id: A0A8B7H1X3
uniprot id: A0A8B7H1X4
uniprot id: A0A8B7H1X5
names: Similarity
messages: Belongs to the peptidase C2 family.

30608:LOC105867198
gene id: 30608:LOC105867198
uniprot id: A0A8B7FTI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PLAC1 family.
messages: Secreted

30608:USP27X
gene id: 30608:USP27X
uniprot id: A0A8B7WZG5
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

30608:A4GNT
gene id: 30608:A4GNT
uniprot id: A0A8B7HY86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

30608:RHO
gene id: 30608:RHO
uniprot id: A0A8B7HU52
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

30608:LOC105877215
gene id: 30608:LOC105877215
uniprot id: A0A8B7H411
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

30608:LOC105877998
gene id: 30608:LOC105877998
uniprot id: A0A8B7H7R5
uniprot id: A0A8B7H7R6
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:LOC105861254
gene id: 30608:LOC105861254
uniprot id: A0A8B7F431
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:UROS
gene id: 30608:UROS
uniprot id: A0A8B7HHU9
uniprot id: A0A8B7HHW9
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

30608:FADS3
gene id: 30608:FADS3
uniprot id: A0A8C5W4G3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:NUBP1
gene id: 30608:NUBP1
uniprot id: A0A8B7HRB2
uniprot id: A0A8B7HRC6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Cell projection
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains. Interacts with KIFC1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105860259
gene id: 30608:LOC105860259
uniprot id: A0A8B7EXY7
uniprot id: A0A8B7X587
uniprot id: A0A8B7X6D6
uniprot id: A0A8B7X6I0
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:NUBPL
gene id: 30608:NUBPL
uniprot id: A0A8B7GYW5
uniprot id: A0A8C5YD66
names: Similarity
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.

30608:VPS4B
gene id: 30608:VPS4B
uniprot id: A0A8C5VNJ9
names: Similarity
messages: Belongs to the AAA ATPase family.

30608:TOMM40L
gene id: 30608:TOMM40L
uniprot id: A0A8B7GLX7
uniprot id: A0A8B7GMG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

30608:FBXO32
gene id: 30608:FBXO32
uniprot id: A0A8C5Y6Y3
names: Subcellular Location Annotation
messages: Nucleus

30608:TMEM184B
gene id: 30608:TMEM184B
uniprot id: A0A8B7EQK1
uniprot id: A0A8B7ES90
names: Subcellular Location Annotation
messages: Membrane

30608:B3GALT6
gene id: 30608:B3GALT6
uniprot id: A0A8B7H5Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:ISM1
gene id: 30608:ISM1
uniprot id: A0A8C5W4G0
names: Similarity
messages: Belongs to the isthmin family.

30608:ESYT3
gene id: 30608:ESYT3
uniprot id: A0A8B7F978
uniprot id: A0A8B7F982
uniprot id: A0A8B7F998
uniprot id: A0A8B7F9D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:LOC105871383
gene id: 30608:LOC105871383
uniprot id: A0A8B7GCM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105870707
gene id: 30608:LOC105870707
uniprot id: A0A8B7G920
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:PDE1B
gene id: 30608:PDE1B
uniprot id: A0A8B7GBQ1
uniprot id: A0A8B7GBS8
uniprot id: A0A8B7X654
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

30608:PDCD5
gene id: 30608:PDCD5
uniprot id: A0A8B7H383
names: Similarity
messages: Belongs to the PDCD5 family.

30608:LOC105859916
gene id: 30608:LOC105859916
uniprot id: A0A8B7EYC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:DYRK1A
gene id: 30608:DYRK1A
uniprot id: A0A8B7HLB3
uniprot id: A0A8B7HLB7
uniprot id: A0A8B7HLC0
uniprot id: A0A8C5VDN6
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

30608:ATXN1L
gene id: 30608:ATXN1L
uniprot id: A0A8B7ETQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

30608:LOC105858168
gene id: 30608:LOC105858168
uniprot id: A0A8B7ENW6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

30608:NDUFA8
gene id: 30608:NDUFA8
uniprot id: A0A8B7GUV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

30608:KCNV1
gene id: 30608:KCNV1
uniprot id: A0A8C5Y9U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the potassium channel family. V (TC 1.A.1.2) subfamily. Kv8.1/KCNV1 sub-subfamily.
messages: Heteromultimer with KCNB1 and KCNB2. Interacts with KCNC4 and KCND1.
messages: Membrane
messages: Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes.

30608:HOMEZ
gene id: 30608:HOMEZ
uniprot id: A0A8B7FJ67
uniprot id: A0A8C5W6S5
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105879294
gene id: 30608:LOC105879294
uniprot id: A0A8B7HDB1
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:GGA1
gene id: 30608:GGA1
uniprot id: A0A8B7HWW1
uniprot id: A0A8B7HWW5
uniprot id: A0A8B7HZE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

30608:EVC
gene id: 30608:EVC
uniprot id: A0A8B7WV22
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

30608:PNPLA6
gene id: 30608:PNPLA6
uniprot id: A0A8B7I5L3
uniprot id: A0A8B7I5L4
uniprot id: A0A8B7I7L8
uniprot id: A0A8B7I8T4
uniprot id: A0A8B7I8T9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:RBP2
gene id: 30608:RBP2
uniprot id: A0A8B7F970
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

30608:CSF2RA
gene id: 30608:CSF2RA
uniprot id: A0A8B7G9F2
uniprot id: A0A8B7G9F6
uniprot id: A0A8B7G9R4
uniprot id: A0A8B7GAI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 5 subfamily.
messages: Membrane

30608:JAK3
gene id: 30608:JAK3
uniprot id: A0A8B7WVF1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.

30608:RFLNB
gene id: 30608:RFLNB
uniprot id: A0A8B7EN68
uniprot id: A0A8C5XGA8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

30608:MTERF4
gene id: 30608:MTERF4
uniprot id: A0A8B7FRI2
uniprot id: A0A8C5Y8P7
names: Similarity
messages: Belongs to the mTERF family.

30608:CPD
gene id: 30608:CPD
uniprot id: A0A8B7EP66
names: Similarity
messages: Belongs to the peptidase M14 family.

30608:ANXA5
gene id: 30608:ANXA5
uniprot id: A0A8B7HR50
names: Domain
names: Function
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.

30608:AURKA
gene id: 30608:AURKA
uniprot id: A0A8B7F7U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: centrosome

30608:HOXA7
gene id: 30608:HOXA7
uniprot id: A0A8B7GYS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

30608:RXRA
gene id: 30608:RXRA
uniprot id: A0A8B7HJK3
uniprot id: A0A8B7HKN9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

30608:PSME3
gene id: 30608:PSME3
uniprot id: A0A8C5VVR8
uniprot id: A0A8C5XNQ9
names: Similarity
messages: Belongs to the PA28 family.

30608:DUS3L
gene id: 30608:DUS3L
uniprot id: A0A8B7G4L3
uniprot id: A0A8C5VRY6
names: Similarity
messages: Belongs to the dus family. Dus3 subfamily.

30608:FAM3A
gene id: 30608:FAM3A
uniprot id: A0A8B7FWI0
uniprot id: A0A8B7FX98
uniprot id: A0A8B7FXA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

30608:DSG4
gene id: 30608:DSG4
uniprot id: A0A8B7WSK2
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

30608:FAM167A
gene id: 30608:FAM167A
uniprot id: A0A8B7FIN5
uniprot id: A0A8B7FIS6
uniprot id: A0A8B7FK35
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

30608:GLB1L
gene id: 30608:GLB1L
uniprot id: A0A8B7ELG8
uniprot id: A0A8B7ELH6
uniprot id: A0A8B7ENS3
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

30608:MUC13
gene id: 30608:MUC13
uniprot id: A0A8B7HIB7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:SEMA3A
gene id: 30608:SEMA3A
uniprot id: A0A8C5UX64
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:MCM8
gene id: 30608:MCM8
uniprot id: A0A8B7WR90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

30608:ATP6V0E2
gene id: 30608:ATP6V0E2
uniprot id: A0A8B7HU19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane

30608:SMIM7
gene id: 30608:SMIM7
uniprot id: A0A8B7FWQ2
uniprot id: A0A8B7FWQ4
names: Similarity
messages: Belongs to the SMIM7 family.

30608:CPNE6
gene id: 30608:CPNE6
uniprot id: A0A8B7FRD9
names: Similarity
messages: Belongs to the copine family.

30608:GRK1
gene id: 30608:GRK1
uniprot id: A0A8C5XDD9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

30608:COL4A1
gene id: 30608:COL4A1
uniprot id: A0A8C5Y9Y9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

30608:LOC105866162
gene id: 30608:LOC105866162
uniprot id: A0A8B7FPJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

30608:NDUFB9
gene id: 30608:NDUFB9
uniprot id: A0A8B7HZH3
uniprot id: A0A8B7HZI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

30608:PEAR1
gene id: 30608:PEAR1
uniprot id: A0A8B7GJM5
uniprot id: A0A8B7GJM9
uniprot id: A0A8B7GKA1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:PHC3
gene id: 30608:PHC3
uniprot id: A0A8B7HCV8
uniprot id: A0A8B7HCW4
uniprot id: A0A8B7HCZ7
uniprot id: A0A8B7HFH1
uniprot id: A0A8B7HFH5
uniprot id: A0A8C5YGR4
uniprot id: A0A8C5YJA3
names: Subcellular Location Annotation
messages: Nucleus

30608:PNOC
gene id: 30608:PNOC
uniprot id: A0A8B7H3L5
uniprot id: A0A8B7H3R4
names: Similarity
messages: Belongs to the opioid neuropeptide precursor family.

30608:PNRC1
gene id: 30608:PNRC1
uniprot id: A0A8B7FEM0
names: Subcellular Location Annotation
messages: Nucleus

30608:ZDHHC13
gene id: 30608:ZDHHC13
uniprot id: A0A8B7FSX6
uniprot id: A0A8C5XF03
names: Caution
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

30608:NSFL1C
gene id: 30608:NSFL1C
uniprot id: A0A8B7FP91
uniprot id: A0A8B7FPI7
names: Subcellular Location Annotation
names: Subunit
messages: Golgi stack
messages: Part of a ternary complex containing STX5A, NSFL1C and VCP. NSFL1C forms a homotrimer that binds to one end of a VCP homohexamer. The complex binds to membranes enriched in phosphatidylethanolamine-containing lipids and promotes Golgi membrane fusion. Interaction with VCIP135 leads to dissociation of the complex via ATP hydrolysis by VCP. Binds ubiquitin and mono-ubiquitinated proteins via its N-terminal UBA-like domain when bound to VCP.

30608:TBK1
gene id: 30608:TBK1
uniprot id: A0A8B7HK55
uniprot id: A0A8B7HK56
names: Subcellular Location Annotation
messages: Cytoplasm

30608:MMP25
gene id: 30608:MMP25
uniprot id: A0A8B7EXK7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

30608:LOC105864771
gene id: 30608:LOC105864771
uniprot id: A0A8B7FJV6
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

30608:LOC105862366
gene id: 30608:LOC105862366
uniprot id: A0A8B7WYM2
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

30608:STPG1
gene id: 30608:STPG1
uniprot id: A0A8B7FD84
uniprot id: A0A8B7FE20
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:ANHX
gene id: 30608:ANHX
uniprot id: A0A8B7F5U6
uniprot id: A0A8B7F5U9
uniprot id: A0A8B7F5X8
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105862114
gene id: 30608:LOC105862114
uniprot id: A0A8B7F761
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105864876
gene id: 30608:LOC105864876
uniprot id: A0A8B7WU25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

30608:LOC105873716
gene id: 30608:LOC105873716
uniprot id: A0A8B7XB66
uniprot id: A0A8B7XCW5
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

30608:ARFGEF2
gene id: 30608:ARFGEF2
uniprot id: A0A8B7G1D9
uniprot id: A0A8B7G299
uniprot id: A0A8B7G2S1
uniprot id: A0A8B7WRH2
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: perinuclear region

30608:MCTS1
gene id: 30608:MCTS1
uniprot id: A0A8B7WYI9
uniprot id: A0A8C5VTD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm

30608:MYO1G
gene id: 30608:MYO1G
uniprot id: A0A8B7G928
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

30608:GALNT1
gene id: 30608:GALNT1
uniprot id: A0A8C5UMJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

30608:ZCCHC4
gene id: 30608:ZCCHC4
uniprot id: A0A8B7EEK4
uniprot id: A0A8B7EF98
uniprot id: A0A8B7EH42
names: Subcellular Location Annotation
messages: Cytoplasm

30608:ACTL9
gene id: 30608:ACTL9
uniprot id: A0A8B7I7U7
names: Similarity
messages: Belongs to the actin family.

30608:SLC4A11
gene id: 30608:SLC4A11
uniprot id: A0A8B7FN65
uniprot id: A0A8B7FN70
uniprot id: A0A8B7FNE4
uniprot id: A0A8B7FNK9
uniprot id: A0A8B7FPI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

30608:TMC3
gene id: 30608:TMC3
uniprot id: A0A8C5YDK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

30608:LOC105865568
gene id: 30608:LOC105865568
uniprot id: A0A8C5XVF2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:CCDC25
gene id: 30608:CCDC25
uniprot id: A0A8C5YDB3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC25 family.
messages: Cell membrane
messages: Endomembrane system
messages: Interacts (via cytoplasmic region) with ILK.

30608:TK2
gene id: 30608:TK2
uniprot id: A0A8B7EUE1
names: Similarity
messages: Belongs to the DCK/DGK family.

30608:GNL2
gene id: 30608:GNL2
uniprot id: A0A8C5V3B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

30608:ANKZF1
gene id: 30608:ANKZF1
uniprot id: A0A8B7ELH1
uniprot id: A0A8B7ELR3
uniprot id: A0A8C5UIY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKZF1/VMS1 family.
messages: Cytoplasm

30608:PTPN6
gene id: 30608:PTPN6
uniprot id: A0A8C5W875
uniprot id: A0A8C5Y978
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

30608:LAMTOR4
gene id: 30608:LAMTOR4
uniprot id: A0A8C5VRJ1
uniprot id: A0A8C5YBZ0
names: Similarity
messages: Belongs to the LAMTOR4 family.

30608:MOXD1
gene id: 30608:MOXD1
uniprot id: A0A8C5UMI7
names: Similarity
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.

30608:SFXN5
gene id: 30608:SFXN5
uniprot id: A0A8B7FBP9
uniprot id: A0A8B7X2P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane
messages: Mitochondrion membrane

30608:PXMP2
gene id: 30608:PXMP2
uniprot id: A0A8B7WTL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

30608:PHYHIPL
gene id: 30608:PHYHIPL
uniprot id: A0A8B7G8N8
uniprot id: A0A8C5Y136
names: Similarity
messages: Belongs to the PHYHIP family.

30608:TEAD1
gene id: 30608:TEAD1
uniprot id: A0A8B7EWJ6
uniprot id: A0A8B7EWJ9
uniprot id: A0A8B7EWK1
uniprot id: A0A8B7EWK2
uniprot id: A0A8B7EWK3
uniprot id: A0A8B7EYH2
uniprot id: A0A8B7EYJ7
names: Subcellular Location Annotation
messages: Nucleus

30608:PHPT1
gene id: 30608:PHPT1
uniprot id: A0A8B7HS15
names: Function
names: Similarity
messages: Belongs to the janus family.
messages: Exhibits phosphohistidine phosphatase activity.

30608:PDE6B
gene id: 30608:PDE6B
uniprot id: A0A8C5V1R8
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

30608:LOC105880097
gene id: 30608:LOC105880097
uniprot id: A0A8B7HGQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

30608:BCL2L13
gene id: 30608:BCL2L13
uniprot id: A0A8B7F611
names: Similarity
messages: Belongs to the Bcl-2 family.

30608:MOB3C
gene id: 30608:MOB3C
uniprot id: A0A8B7H557
uniprot id: A0A8B7H559
uniprot id: A0A8B7H562
uniprot id: A0A8B7H564
uniprot id: A0A8B7H7G8
uniprot id: A0A8B7XBM9
uniprot id: A0A8C5VQZ1
names: Similarity
messages: Belongs to the MOB1/phocein family.
messages: Belongs to the protein kinase superfamily.

30608:LOC105883413
gene id: 30608:LOC105883413
uniprot id: A0A8B7HV11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:S100PBP
gene id: 30608:S100PBP
uniprot id: A0A8B7GDT4
uniprot id: A0A8B7GEQ3
names: Subcellular Location Annotation
messages: Nucleus

30608:FAM118A
gene id: 30608:FAM118A
uniprot id: A0A8B7X6K9
names: Similarity
messages: Belongs to the FAM118 family.

30608:POMT1
gene id: 30608:POMT1
uniprot id: A0A8B7EY14
uniprot id: A0A8C5VZI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

30608:UTS2
gene id: 30608:UTS2
uniprot id: A0A8B7WQB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

30608:LIX1L
gene id: 30608:LIX1L
uniprot id: A0A8B7G5A0
names: Similarity
messages: Belongs to the LIX1 family.

30608:ACER1
gene id: 30608:ACER1
uniprot id: A0A8B7G651
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Membrane

30608:CCDC94
gene id: 30608:CCDC94
uniprot id: A0A8B7GNP3
uniprot id: A0A8C5VQH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWC16 family. YJU2 subfamily.
messages: Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.
messages: Nucleus
messages: Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex.

30608:NCAPG
gene id: 30608:NCAPG
uniprot id: A0A8B7EF97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

30608:SLC43A2
gene id: 30608:SLC43A2
uniprot id: A0A8B7EMY0
uniprot id: A0A8B7EMY4
uniprot id: A0A8B7EN47
names: Subcellular Location Annotation
messages: Membrane

30608:ORC1
gene id: 30608:ORC1
uniprot id: A0A8B7H5K3
uniprot id: A0A8B7XBV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of ORC, a complex composed of at least 6 subunits: ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase. Interacts with CDC6 and KAT7/HBO1. Interacts with LRWD1 predominantly during the G1 phase and with less affinity during mitosis, when phosphorylated.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus

30608:VAT1L
gene id: 30608:VAT1L
uniprot id: A0A8B7F9Q9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

30608:RPL23
gene id: 30608:RPL23
uniprot id: A0A8B7GFA0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Component of the large ribosomal subunit.

30608:ALKBH1
gene id: 30608:ALKBH1
uniprot id: A0A8C5W576
names: Cofactor
names: Similarity
messages: Belongs to the alkB family.
messages: Binds 1 Fe(2+) ion per subunit.

30608:ZKSCAN4
gene id: 30608:ZKSCAN4
uniprot id: A0A8B7ET74
uniprot id: A0A8C5YDH8
names: Subcellular Location Annotation
messages: Nucleus

30608:OC90
gene id: 30608:OC90
uniprot id: A0A8C5UP06
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

30608:RER1
gene id: 30608:RER1
uniprot id: A0A8C5VQX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

30608:CHAF1B
gene id: 30608:CHAF1B
uniprot id: A0A8B7HLD5
uniprot id: A0A8B7HMN3
names: Subcellular Location Annotation
messages: Nucleus

30608:GABRG3
gene id: 30608:GABRG3
uniprot id: A0A8B7G0G9
uniprot id: A0A8C5XAR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:CACNG1
gene id: 30608:CACNG1
uniprot id: A0A8C5Y2A5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

30608:LOC105883367
gene id: 30608:LOC105883367
uniprot id: A0A8B7HX15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC109730707
gene id: 30608:LOC109730707
uniprot id: A0A8B7X5K9
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105884796
gene id: 30608:LOC105884796
uniprot id: A0A8B7XEB6
names: Similarity
messages: Belongs to the SAPAP family.

30608:ZSCAN21
gene id: 30608:ZSCAN21
uniprot id: A0A8B7FY69
names: Subcellular Location Annotation
messages: Nucleus

30608:PRSS12
gene id: 30608:PRSS12
uniprot id: A0A8B7WXC7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:MATN3
gene id: 30608:MATN3
uniprot id: A0A8B7HY72
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:SCN11A
gene id: 30608:SCN11A
uniprot id: A0A8B7ETC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

30608:GGA3
gene id: 30608:GGA3
uniprot id: A0A8B7HBP5
uniprot id: A0A8B7HBP7
uniprot id: A0A8B7HBP8
uniprot id: A0A8B7HEC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

30608:VPS41
gene id: 30608:VPS41
uniprot id: A0A8B7H8S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways.
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network

30608:ELAVL2
gene id: 30608:ELAVL2
uniprot id: A0A8B7GPY9
uniprot id: A0A8B7GPZ2
uniprot id: A0A8B7GPZ7
uniprot id: A0A8B7GQ01
uniprot id: A0A8B7GQ89
uniprot id: A0A8B7GQF1
uniprot id: A0A8B7GRI7
uniprot id: A0A8C5VGS9
names: Similarity
messages: Belongs to the RRM elav family.

30608:KIF1B
gene id: 30608:KIF1B
uniprot id: A0A8B7I7B4
uniprot id: A0A8B7I7B8
uniprot id: A0A8B7I7F2
uniprot id: A0A8B7I9A8
uniprot id: A0A8B7IAM0
uniprot id: A0A8B7WPV6
uniprot id: A0A8B7WPW4
uniprot id: A0A8C5YBK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: axon

30608:LOC105856044
gene id: 30608:LOC105856044
uniprot id: A0A8B7EF93
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

30608:PDE6C
gene id: 30608:PDE6C
uniprot id: A0A8B7GGG8
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

30608:LOC105883502
gene id: 30608:LOC105883502
uniprot id: A0A8B7HXL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:OXSR1
gene id: 30608:OXSR1
uniprot id: A0A8B7FSN8
uniprot id: A0A8C5YGJ7
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

30608:NELL1
gene id: 30608:NELL1
uniprot id: A0A8B7E9Y5
uniprot id: A0A8B7EAJ5
uniprot id: A0A8B7X3N2
uniprot id: A0A8C5V816
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:TSPAN4
gene id: 30608:TSPAN4
uniprot id: A0A8B7GPM7
uniprot id: A0A8B7GPU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

30608:PRLHR
gene id: 30608:PRLHR
uniprot id: A0A8B7EJZ7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:LOC105865212
gene id: 30608:LOC105865212
uniprot id: A0A8B7WKW9
names: Similarity
messages: Belongs to the TMEM14 family.

30608:AK3
gene id: 30608:AK3
uniprot id: A0A8B7EFZ1
uniprot id: A0A8B7EHX6
uniprot id: A0A8B7EHY4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

30608:SEPT7
gene id: 30608:SEPT7
uniprot id: A0A8B7H8P7
uniprot id: A0A8B7H8Q3
uniprot id: A0A8B7H8Q4
uniprot id: A0A8B7HBC9
uniprot id: A0A8B7XCF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Filament-forming cytoskeletal GTPase.
messages: Midbody
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.
messages: cilium axoneme
messages: flagellum
messages: kinetochore
messages: spindle

30608:LOC105855631
gene id: 30608:LOC105855631
uniprot id: A0A8C5UV57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

30608:VPS29
gene id: 30608:VPS29
uniprot id: A0A8B7HK11
uniprot id: A0A8B7HK12
uniprot id: A0A8B7HL73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
messages: Belongs to the VPS29 family.
messages: Endosome membrane

30608:FAM118B
gene id: 30608:FAM118B
uniprot id: A0A8B7GW70
uniprot id: A0A8B7X5I1
uniprot id: A0A8C5XLL5
names: Similarity
messages: Belongs to the FAM118 family.

30608:TNC
gene id: 30608:TNC
uniprot id: A0A8B7GME6
uniprot id: A0A8B7GMQ8
uniprot id: A0A8B7GMY1
uniprot id: A0A8B7GNQ9
uniprot id: A0A8C5W160
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:CFAP126
gene id: 30608:CFAP126
uniprot id: A0A8B7GMA1
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the Flattop family.

30608:RPS16
gene id: 30608:RPS16
uniprot id: A0A8C5VF03
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

30608:EXOSC1
gene id: 30608:EXOSC1
uniprot id: A0A8B7GJS9
names: Subcellular Location Annotation
messages: Cytoplasm

30608:TMEM45B
gene id: 30608:TMEM45B
uniprot id: A0A8B7HPS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

30608:NFIB
gene id: 30608:NFIB
uniprot id: A0A8B7GPK8
uniprot id: A0A8B7GPL3
uniprot id: A0A8B7GPL6
uniprot id: A0A8B7GPM2
uniprot id: A0A8B7GPV2
uniprot id: A0A8B7GPW1
uniprot id: A0A8B7GQ20
uniprot id: A0A8B7GR50
uniprot id: A0A8B7GR60
uniprot id: A0A8C5W7E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

30608:ATP4B
gene id: 30608:ATP4B
uniprot id: A0A8C6EH33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

30608:DMRT3
gene id: 30608:DMRT3
uniprot id: A0A8C5XS91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

30608:LOC105875331
gene id: 30608:LOC105875331
uniprot id: A0A8B7GXV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105881243
gene id: 30608:LOC105881243
uniprot id: A0A8B7HL60
uniprot id: A0A8B7HL64
uniprot id: A0A8B7HNN1
names: Similarity
messages: Belongs to the multicopper oxidase family.

30608:CCDC103
gene id: 30608:CCDC103
uniprot id: A0A8B7HVW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC103/PR46b family.
messages: Cytoplasm
messages: Dynein-attachment factor required for cilia motility.
messages: Homodimer.
messages: flagellum

30608:LOC105866209
gene id: 30608:LOC105866209
uniprot id: A0A8B7FPR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

30608:LOC105882802
gene id: 30608:LOC105882802
uniprot id: A0A8C5YEQ3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

30608:ADA
gene id: 30608:ADA
uniprot id: A0A8B7HGH1
uniprot id: A0A8B7HGJ5
uniprot id: A0A8B7HJ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
messages: Cell junction
messages: Cell membrane
messages: Cytoplasmic vesicle lumen

30608:FAM83D
gene id: 30608:FAM83D
uniprot id: A0A8B7FPF2
names: Similarity
messages: Belongs to the FAM83 family.

30608:LOC105870634
gene id: 30608:LOC105870634
uniprot id: A0A8B7G8Q1
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:SLC37A4
gene id: 30608:SLC37A4
uniprot id: A0A8B7GZ84
uniprot id: A0A8C5URP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

30608:AARS
gene id: 30608:AARS
uniprot id: A0A8B7GWK5
names: Cofactor
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: ISGylated.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

30608:NDUFS5
gene id: 30608:NDUFS5
uniprot id: A0A8B7HER8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Membrane
messages: Mitochondrion inner membrane

30608:OAS1
gene id: 30608:OAS1
uniprot id: A0A8B7FS18
uniprot id: A0A8B7FT09
uniprot id: A0A8B7WTS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-5A synthase family.
messages: Cytoplasm

30608:LOC105858476
gene id: 30608:LOC105858476
uniprot id: A0A8B7EPX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:BCAP31
gene id: 30608:BCAP31
uniprot id: A0A8B7FUT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a role in the export of secreted proteins in the ER.

30608:RPL10L
gene id: 30608:RPL10L
uniprot id: A0A8B7F3Q0
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

30608:SPINK4
gene id: 30608:SPINK4
uniprot id: A0A8C6EKK5
names: Subcellular Location Annotation
messages: Secreted

30608:CAPN6
gene id: 30608:CAPN6
uniprot id: A0A8B7FAY6
names: Caution
names: Similarity
messages: Belongs to the peptidase C2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:NOTCH2
gene id: 30608:NOTCH2
uniprot id: A0A8B7G553
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

30608:TBL1X
gene id: 30608:TBL1X
uniprot id: A0A8B7HLI7
uniprot id: A0A8B7WYX5
uniprot id: A0A8B7WZG8
uniprot id: A0A8B7X0N8
names: Similarity
messages: Belongs to the WD repeat EBI family.

30608:SLC2A2
gene id: 30608:SLC2A2
uniprot id: A0A8B7ECB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Membrane

30608:LOC105879892
gene id: 30608:LOC105879892
uniprot id: A0A8B7HFU3
names: Similarity
messages: Belongs to the cystatin family.

30608:SLC25A48
gene id: 30608:SLC25A48
uniprot id: A0A8B7G627
uniprot id: A0A8B7G6T6
uniprot id: A0A8B7WQU4
uniprot id: A0A8C5V047
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:TPRKB
gene id: 30608:TPRKB
uniprot id: A0A8C5XVR3
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

30608:LOC105877255
gene id: 30608:LOC105877255
uniprot id: A0A8B7WZZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation.
messages: centrosome

30608:FKBP4
gene id: 30608:FKBP4
uniprot id: A0A8B7HM21
names: Subcellular Location Annotation
messages: Mitochondrion
messages: cytoskeleton
messages: cytosol

30608:OVOL1
gene id: 30608:OVOL1
uniprot id: A0A8B7HCW5
uniprot id: A0A8C5W233
names: Subcellular Location Annotation
messages: Nucleus

30608:JAKMIP3
gene id: 30608:JAKMIP3
uniprot id: A0A8B7HI00
uniprot id: A0A8B7HI26
uniprot id: A0A8B7WM43
uniprot id: A0A8B7WM47
uniprot id: A0A8B7WM48
uniprot id: A0A8B7WM52
uniprot id: A0A8B7WM68
uniprot id: A0A8B7WM72
uniprot id: A0A8B7WM98
uniprot id: A0A8B7WN85
names: Similarity
messages: Belongs to the JAKMIP family.

30608:AGTPBP1
gene id: 30608:AGTPBP1
uniprot id: A0A8B7HX60
uniprot id: A0A8B7HZ75
uniprot id: A0A8B7XAM4
uniprot id: A0A8C5VJJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

30608:AU129 gp04
gene id: 30608:AU129_gp04
uniprot id: A0A0U2I1K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4 family.
messages: Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

30608:ACYP1
gene id: 30608:ACYP1
uniprot id: A0A8B7ETF3
uniprot id: A0A8C5YE14
names: Similarity
messages: Belongs to the acylphosphatase family.

30608:CHAC1
gene id: 30608:CHAC1
uniprot id: A0A8B7GHA9
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

30608:PPP3R2
gene id: 30608:PPP3R2
uniprot id: A0A8B7GNB4
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

30608:ATOH7
gene id: 30608:ATOH7
uniprot id: A0A8B7G7Q8
names: Subcellular Location Annotation
messages: Nucleus
messages: Perikaryon
messages: axon

30608:MLH3
gene id: 30608:MLH3
uniprot id: A0A8B7ER87
uniprot id: A0A8B7ETA9
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

30608:GPR108
gene id: 30608:GPR108
uniprot id: A0A8B7G5J6
uniprot id: A0A8B7G641
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105871638
gene id: 30608:LOC105871638
uniprot id: A0A8B7X170
names: Similarity
messages: Belongs to the SNF7 family.

30608:F5
gene id: 30608:F5
uniprot id: A0A8B7X1D4
names: Similarity
messages: Belongs to the multicopper oxidase family.

30608:TSFM
gene id: 30608:TSFM
uniprot id: A0A8C5VBA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Mitochondrion

30608:CBS
gene id: 30608:CBS
uniprot id: A0A8B7HCH7
uniprot id: A0A8B7HCI1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

30608:CSNK2A1
gene id: 30608:CSNK2A1
uniprot id: A0A8B7FNY4
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:BAP1
gene id: 30608:BAP1
uniprot id: A0A8B7GU63
names: Similarity
messages: Belongs to the peptidase C12 family.

30608:PIGK
gene id: 30608:PIGK
uniprot id: A0A8B7I139
names: Similarity
names: Subunit
messages: Belongs to the peptidase C13 family.
messages: Forms a complex with PIGT, PIGS, PIGU and GAA1.

30608:LAMP2
gene id: 30608:LAMP2
uniprot id: A0A8B7EIK7
uniprot id: A0A8B7EJK1
uniprot id: A0A8C5XYD8
uniprot id: A0A8C6ELC6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

30608:LOC105867760
gene id: 30608:LOC105867760
uniprot id: A0A8B7G9B5
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105857372
gene id: 30608:LOC105857372
uniprot id: A0A8C5W2Y2
names: Similarity
messages: Belongs to the NSG family.

30608:NUTF2
gene id: 30608:NUTF2
uniprot id: A0A8B7EU43
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

30608:ADTRP
gene id: 30608:ADTRP
uniprot id: A0A8B7FJY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

30608:LOC105861972
gene id: 30608:LOC105861972
uniprot id: A0A8C5XST0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

30608:LOC105864452
gene id: 30608:LOC105864452
uniprot id: A0A8B7FH57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NAV3
gene id: 30608:NAV3
uniprot id: A0A8B7FC65
uniprot id: A0A8B7FC68
uniprot id: A0A8B7FC70
uniprot id: A0A8B7FC71
uniprot id: A0A8B7FC73
uniprot id: A0A8B7FC76
uniprot id: A0A8B7FC80
uniprot id: A0A8B7FC82
uniprot id: A0A8B7FCD2
uniprot id: A0A8B7FCW2
uniprot id: A0A8B7FCW9
uniprot id: A0A8B7FCX5
uniprot id: A0A8C5VCE4
names: Similarity
messages: Belongs to the Nav/unc-53 family.

30608:TJAP1
gene id: 30608:TJAP1
uniprot id: A0A8B7GY31
uniprot id: A0A8B7GY76
names: Subcellular Location Annotation
messages: Membrane

30608:RRAGB
gene id: 30608:RRAGB
uniprot id: A0A8B7FT76
uniprot id: A0A8B7FTA4
uniprot id: A0A8B7FTX9
uniprot id: A0A8C6EL39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

30608:RAD21L1
gene id: 30608:RAD21L1
uniprot id: A0A8B7FNC2
uniprot id: A0A8B7FNL3
uniprot id: A0A8B7FNR7
uniprot id: A0A8B7FPN2
uniprot id: A0A8C6EKV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

30608:SIAH1
gene id: 30608:SIAH1
uniprot id: A0A8B7I3G4
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

30608:HEATR5B
gene id: 30608:HEATR5B
uniprot id: A0A8B7I021
uniprot id: A0A8B7I023
uniprot id: A0A8B7I255
uniprot id: A0A8B7I2R8
names: Similarity
messages: Belongs to the HEATR5 family.

30608:WDR18
gene id: 30608:WDR18
uniprot id: A0A8B7F0G1
uniprot id: A0A8B7F257
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat IPI3/WDR18 family.
messages: Component of the 5FMC complex, at least composed of PELP1, LAS1L, TEX10, WDR18 and SENP3; the complex interacts with methylated CHTOP and ZNF148. Interacts with NOL9. Component of the PELP1 complex, composed of at least PELP1, TEX10 and WDR18. The complex interacts with pre-60S ribosome particles.
messages: Cytoplasm
messages: Dynein axonemal particle
messages: Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes. Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit. May play a role during development.
messages: nucleolus
messages: nucleoplasm

30608:SERBP1
gene id: 30608:SERBP1
uniprot id: A0A8B7GIJ5
uniprot id: A0A8B7GIX5
uniprot id: A0A8B7GJ73
uniprot id: A0A8B7GJL1
names: Similarity
messages: Belongs to the SERBP1-HABP4 family.

30608:NUP155
gene id: 30608:NUP155
uniprot id: A0A8B7EC31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.
messages: nuclear pore complex

30608:SPPL3
gene id: 30608:SPPL3
uniprot id: A0A8B7FSG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

30608:PTMS
gene id: 30608:PTMS
uniprot id: A0A8B7G1S4
uniprot id: A0A8B7G370
names: Similarity
messages: Belongs to the pro/parathymosin family.

30608:FUZ
gene id: 30608:FUZ
uniprot id: A0A8B7FNM2
uniprot id: A0A8C5XFX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fuzzy family.
messages: cytoskeleton

30608:TAP1
gene id: 30608:TAP1
uniprot id: A0A8B7I979
uniprot id: A0A8B7IAI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily.
messages: Membrane

30608:CELF3
gene id: 30608:CELF3
uniprot id: A0A8B7GJG7
uniprot id: A0A8B7GJT9
uniprot id: A0A8C5UXB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

30608:SLC26A1
gene id: 30608:SLC26A1
uniprot id: A0A8B7WQ24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane
messages: Sodium-independent sulfate anion transporter. Can transport other anions including bicarbonate, thiosulfate and oxalate.

30608:HMGCR
gene id: 30608:HMGCR
uniprot id: A0A8B7HNA8
uniprot id: A0A8B7HND1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane

30608:LOC105877408
gene id: 30608:LOC105877408
uniprot id: A0A8B7H6S5
names: Subcellular Location Annotation
messages: Membrane

30608:UROD
gene id: 30608:UROD
uniprot id: A0A8B7H520
uniprot id: A0A8B7H793
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

30608:IGFBP4
gene id: 30608:IGFBP4
uniprot id: A0A8C5UWA4
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds IGF2 more than IGF1.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:SUDS3
gene id: 30608:SUDS3
uniprot id: A0A8B7FSM4
names: Subcellular Location Annotation
messages: Nucleus

30608:TBXA2R
gene id: 30608:TBXA2R
uniprot id: A0A8B7GQ84
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:RIPOR2
gene id: 30608:RIPOR2
uniprot id: A0A8B7EP80
uniprot id: A0A8B7EPC4
uniprot id: A0A8B7EQU5
uniprot id: A0A8B7ERF5
uniprot id: A0A8C5VUV3
names: Similarity
messages: Belongs to the RIPOR family.

30608:LIPA
gene id: 30608:LIPA
uniprot id: A0A8B7GD60
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

30608:CASR
gene id: 30608:CASR
uniprot id: A0A8B7HFX4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:CHRDL1
gene id: 30608:CHRDL1
uniprot id: A0A8B7FBE7
uniprot id: A0A8B7FBF9
uniprot id: A0A8B7FBG0
names: Subcellular Location Annotation
messages: Secreted

30608:PPP1R7
gene id: 30608:PPP1R7
uniprot id: A0A8C5XZQ7
names: Similarity
messages: Belongs to the SDS22 family.

30608:RBM3
gene id: 30608:RBM3
uniprot id: A0A8B7EG94
uniprot id: A0A8B7EGP4
uniprot id: A0A8B7EIQ0
names: Subcellular Location Annotation
messages: Cytoplasm

30608:HMCN1
gene id: 30608:HMCN1
uniprot id: A0A8B7ECL9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:CHRNA6
gene id: 30608:CHRNA6
uniprot id: A0A8B7WUA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:EGR1
gene id: 30608:EGR1
uniprot id: A0A8C5YAE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus
messages: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death.

30608:LOC105861463
gene id: 30608:LOC105861463
uniprot id: A0A8B7WUT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane

30608:LOC105857881
gene id: 30608:LOC105857881
uniprot id: A0A8B7ENZ0
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105868420
gene id: 30608:LOC105868420
uniprot id: A0A8B7FZ06
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: gap junction

30608:ST8SIA6
gene id: 30608:ST8SIA6
uniprot id: A0A8B7WWI5
uniprot id: A0A8C5XT44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

30608:CTSA
gene id: 30608:CTSA
uniprot id: A0A8C5VNE9
names: Similarity
messages: Belongs to the peptidase S10 family.

30608:NDUFB2
gene id: 30608:NDUFB2
uniprot id: A0A8C5UQN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

30608:GOLGA6B
gene id: 30608:GOLGA6B
uniprot id: A0A8B7X322
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

30608:FADS2
gene id: 30608:FADS2
uniprot id: A0A8B7HAH3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:PRM1
gene id: 30608:PRM1
uniprot id: A0A8B7HQQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protamine P1 family.
messages: Chromosome
messages: Nucleus
messages: Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex.

30608:LOC105861289
gene id: 30608:LOC105861289
uniprot id: A0A8B7F2K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SAP30
gene id: 30608:SAP30
uniprot id: A0A8C5V918
names: Similarity
messages: Belongs to the SAP30 family.

30608:PARP10
gene id: 30608:PARP10
uniprot id: A0A8B7G1N4
names: Similarity
messages: Belongs to the ARTD/PARP family.

30608:LOC105861905
gene id: 30608:LOC105861905
uniprot id: A0A8C5XHF6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

30608:KCNH2
gene id: 30608:KCNH2
uniprot id: A0A8B7HU62
uniprot id: A0A8B7HW99
uniprot id: A0A8C5UU22
uniprot id: A0A8C5VLJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.1/KCNH2 sub-subfamily.
messages: Membrane

30608:TMEM244
gene id: 30608:TMEM244
uniprot id: A0A8B7ECV9
names: Subcellular Location Annotation
messages: Membrane

30608:ERCC4
gene id: 30608:ERCC4
uniprot id: A0A8B7EB68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPF family.
messages: Nucleus

30608:KRT76
gene id: 30608:KRT76
uniprot id: A0A8B7G878
uniprot id: A0A8B7G887
names: Similarity
messages: Belongs to the intermediate filament family.

30608:NUP93
gene id: 30608:NUP93
uniprot id: A0A8B7FR20
uniprot id: A0A8C5XKB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: Nucleus membrane
messages: Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance.
messages: nuclear pore complex

30608:TSHR
gene id: 30608:TSHR
uniprot id: A0A8B7FXG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

30608:LOC105884311
gene id: 30608:LOC105884311
uniprot id: A0A8B7X7W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

30608:GLIPR1L1
gene id: 30608:GLIPR1L1
uniprot id: A0A8C5V4E5
names: Similarity
messages: Belongs to the CRISP family.

30608:SAMHD1
gene id: 30608:SAMHD1
uniprot id: A0A8B7FPL7
uniprot id: K4K7U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAMHD1 family.
messages: Chromosome

30608:CFTR
gene id: 30608:CFTR
uniprot id: A0A8B7G362
uniprot id: A0A8B7G372
uniprot id: A0A8C5Y6D9
uniprot id: Q2QL83
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily.
messages: Binds and hydrolyzes ATP via the two cytoplasmic ABC transporter nucleotide-binding domains. The two ATP-binding domains interact with each other, forming a head-to-tail dimer. Normal ATPase activity requires interaction between the two domains. The first ABC transporter nucleotide-binding domain has no ATPase activity by itself.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3)(-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. Modulates the activity of the epithelial sodium channel (ENaC) complex, in part by regulating the cell surface expression of the ENaC complex. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the transporter SLC4A7. Can inhibit the chloride channel activity of ANO1 (By similarity). Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation (By similarity).
messages: Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer; does not require oligomerization for channel activity. May form oligomers in the membrane (By similarity). Interacts with SLC26A3, SLC26A6 and NHERF1 (By similarity). Interacts with SHANK2 (By similarity). Interacts with MYO6 (By similarity). Interacts (via C-terminus) with GOPC (via PDZ domain); this promotes CFTR internalization and thereby decreases channel activity. Interacts with SLC4A7 through NHERF1. Found in a complex with MYO5B and RAB11A. Interacts with ANO1. Interacts with SLC26A8 (By similarity). Interacts with AHCYL1; the interaction increases CFTR activity (By similarity). Interacts with CSE1L (By similarity). The core-glycosylated form interacts with GORASP2 (via PDZ GRASP-type 1 domain) in respone to ER stress (By similarity). Interacts with MARCHF2; the interaction leads to CFTR ubiqtuitination and degradation (By similarity).
messages: N-glycosylated.
messages: Nucleus
messages: Phosphorylated; cAMP treatment promotes phosphorylation and activates the channel. Dephosphorylation decreases the ATPase activity (in vitro). Phosphorylation at PKA sites activates the channel. Phosphorylation at PKC sites enhances the response to phosphorylation by PKA. Phosphorylated by AMPK; this inhibits channel activity.
messages: Recycling endosome membrane
messages: The PDZ-binding motif mediates interactions with GOPC and with the SLC4A7, NHERF1/EBP50 complex.
messages: The disordered R region mediates channel activation when it is phosphorylated, but not in the absence of phosphorylation.
messages: Ubiquitinated, leading to its degradation in the lysosome. Deubiquitination by USP10 in early endosomes enhances its endocytic recycling to the cell membrane. Ubiquitinated by RNF185 during ER stress. Ubiquitinated by MARCHF2 (By similarity).

30608:CDC42EP1
gene id: 30608:CDC42EP1
uniprot id: A0A8C5VXK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

30608:PKN2
gene id: 30608:PKN2
uniprot id: A0A8B7F9I8
uniprot id: A0A8C5XFQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cleavage furrow
messages: Midbody
messages: Nucleus

30608:ADAMTS18
gene id: 30608:ADAMTS18
uniprot id: A0A8B7WSI2
uniprot id: A0A8B7WSI6
uniprot id: A0A8B7WSK9
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:GAL3ST4
gene id: 30608:GAL3ST4
uniprot id: A0A8B7WQ61
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

30608:CBR4
gene id: 30608:CBR4
uniprot id: A0A8B7GSC4
uniprot id: A0A8B7GTQ8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:FERMT3
gene id: 30608:FERMT3
uniprot id: A0A8C5V4R6
names: Similarity
messages: Belongs to the kindlin family.

30608:CAP1
gene id: 30608:CAP1
uniprot id: A0A8B7EB26
uniprot id: A0A8B7WKW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane
messages: Membrane

30608:FAM208B
gene id: 30608:FAM208B
uniprot id: A0A8B7ENX3
uniprot id: A0A8B7ENZ1
uniprot id: A0A8B7ENZ7
uniprot id: A0A8B7WWF4
uniprot id: A0A8B7WY55
names: Similarity
messages: Belongs to the TASOR family.

30608:PPP1R9B
gene id: 30608:PPP1R9B
uniprot id: A0A8B7I349
names: Subcellular Location Annotation
messages: cytoskeleton

30608:FRRS1
gene id: 30608:FRRS1
uniprot id: A0A8B7F873
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRRS1 family.
messages: Membrane

30608:LOC105867595
gene id: 30608:LOC105867595
uniprot id: A0A8B7FWC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative pheromone receptor.

30608:MTFR2
gene id: 30608:MTFR2
uniprot id: A0A8B7EJQ6
uniprot id: A0A8B7EKY2
uniprot id: A0A8B7EM36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

30608:LOC105884008
gene id: 30608:LOC105884008
uniprot id: A0A8B7HY56
uniprot id: A0A8B7I0G0
names: Similarity
messages: Belongs to the Schlafen family. Subgroup III subfamily.

30608:PCID2
gene id: 30608:PCID2
uniprot id: A0A8B7GER8
names: Similarity
messages: Belongs to the CSN12 family.

30608:SUZ12
gene id: 30608:SUZ12
uniprot id: A0A8B7EIB2
names: Similarity
messages: Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.

30608:LOC105858219
gene id: 30608:LOC105858219
uniprot id: A0A8B7ER30
names: Similarity
messages: Belongs to the aldo/keto reductase family.

30608:BRK1
gene id: 30608:BRK1
uniprot id: A0A8C5Y6Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRK1 family.
messages: cytoskeleton

30608:ZWILCH
gene id: 30608:ZWILCH
uniprot id: A0A8B7FY89
uniprot id: A0A8B7FYC5
uniprot id: A0A8C5XWK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZWILCH family.
messages: Component of the RZZ complex.
messages: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
messages: kinetochore

30608:ITGA2B
gene id: 30608:ITGA2B
uniprot id: A0A8B7HXW5
uniprot id: A0A8B7HY21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

30608:PRDM1
gene id: 30608:PRDM1
uniprot id: A0A8B7FJD5
uniprot id: A0A8B7FJE0
uniprot id: A0A8B7FJE3
uniprot id: A0A8B7FJL6
uniprot id: A0A8C5XHN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.
messages: Nucleus
messages: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.

30608:HUS1B
gene id: 30608:HUS1B
uniprot id: A0A8B7GLQ1
names: Similarity
messages: Belongs to the HUS1 family.

30608:ORAI2
gene id: 30608:ORAI2
uniprot id: A0A8B7FYD4
uniprot id: A0A8C5V8W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

30608:PCSK9
gene id: 30608:PCSK9
uniprot id: A0A8B7FAG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell surface
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Endosome
messages: Golgi apparatus
messages: Lysosome

30608:LOC105883425
gene id: 30608:LOC105883425
uniprot id: A0A8B7HV39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PHF20
gene id: 30608:PHF20
uniprot id: A0A8B7FMY7
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105865110
gene id: 30608:LOC105865110
uniprot id: A0A8B7FK47
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

30608:NDUFB11
gene id: 30608:NDUFB11
uniprot id: A0A8B7FAM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB11 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane

30608:SEC31B
gene id: 30608:SEC31B
uniprot id: A0A8B7GM54
uniprot id: A0A8B7GM68
uniprot id: A0A8B7GMA2
uniprot id: A0A8B7GMF8
uniprot id: A0A8B7GMH3
uniprot id: A0A8B7GMI6
uniprot id: A0A8B7GMP1
uniprot id: A0A8B7GMS4
uniprot id: A0A8B7GMS9
uniprot id: A0A8B7GNK7
uniprot id: A0A8B7WLU7
uniprot id: A0A8B7WMS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: Endoplasmic reticulum membrane

30608:SLC17A2
gene id: 30608:SLC17A2
uniprot id: A0A8B7EPB7
uniprot id: A0A8B7WKD2
uniprot id: A0A8B7WKF2
uniprot id: A0A8B7WKG5
uniprot id: A0A8C5VCQ4
names: Subcellular Location Annotation
messages: Membrane

30608:TMEM258
gene id: 30608:TMEM258
uniprot id: A0A8B7HAI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST5 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

30608:SNX2
gene id: 30608:SNX2
uniprot id: A0A8B7I0B8
uniprot id: A0A8B7I342
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium

30608:TBCE
gene id: 30608:TBCE
uniprot id: A0A8B7EGQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCE family.
messages: Cytoplasm

30608:LOC105878681
gene id: 30608:LOC105878681
uniprot id: A0A8B7HAS5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:LOC105859915
gene id: 30608:LOC105859915
uniprot id: A0A8B7EWC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:RET
gene id: 30608:RET
uniprot id: A0A8C5UWW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane
messages: Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.

30608:LOC105862473
gene id: 30608:LOC105862473
uniprot id: A0A8B7F8E9
uniprot id: A0A8B7F8S8
uniprot id: A0A8C5UM77
names: Similarity
messages: Belongs to the peptidase C14A family.

30608:ESX1
gene id: 30608:ESX1
uniprot id: A0A8B7HZ02
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105880672
gene id: 30608:LOC105880672
uniprot id: A0A8B7HIY4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

30608:LOC105863119
gene id: 30608:LOC105863119
uniprot id: A0A8B7FBN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105873909
gene id: 30608:LOC105873909
uniprot id: A0A8C6ELI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RutC family.
messages: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.
messages: Peroxisome

30608:LOC105872331
gene id: 30608:LOC105872331
uniprot id: A0A8B7GG39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

30608:PFKFB2
gene id: 30608:PFKFB2
uniprot id: A0A8B7G276
uniprot id: A0A8B7G283
uniprot id: A0A8B7G376
uniprot id: A0A8B7G3R1
uniprot id: A0A8B7WXU4
uniprot id: A0A8C5W1A4
uniprot id: A0A8C5Y6F3
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

30608:UCHL3
gene id: 30608:UCHL3
uniprot id: A0A8B7EDN9
uniprot id: A0A8B7EE98
names: Similarity
messages: Belongs to the peptidase C12 family.

30608:WDR17
gene id: 30608:WDR17
uniprot id: A0A8B7GSH7
names: Subcellular Location Annotation
messages: COPI-coated vesicle membrane

30608:TAF8
gene id: 30608:TAF8
uniprot id: A0A8B7GYE3
uniprot id: A0A8B7GYG4
uniprot id: A0A8B7GYJ5
uniprot id: A0A8B7H0B0
uniprot id: A0A8C5VD23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF8 family.
messages: Nucleus

30608:HSPH1
gene id: 30608:HSPH1
uniprot id: A0A8B7F284
uniprot id: A0A8C5W422
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm

30608:FOXK1
gene id: 30608:FOXK1
uniprot id: A0A8B7FYK2
uniprot id: A0A8B7FYK6
uniprot id: A0A8B7FZK1
names: Subcellular Location Annotation
messages: Nucleus

30608:PHKA1
gene id: 30608:PHKA1
uniprot id: A0A8B7HPS1
uniprot id: A0A8B7HPS3
uniprot id: A0A8C5XPN2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

30608:AIG1
gene id: 30608:AIG1
uniprot id: A0A8B7G013
uniprot id: A0A8B7G0V2
uniprot id: A0A8B7G189
uniprot id: A0A8C5XE55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

30608:UBE2N
gene id: 30608:UBE2N
uniprot id: A0A8B7HS39
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:WARS
gene id: 30608:WARS
uniprot id: A0A8B7F4G3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

30608:SERPINB7
gene id: 30608:SERPINB7
uniprot id: A0A8B7H1B3
uniprot id: A0A8B7H1B9
uniprot id: A0A8C5XL68
names: Similarity
messages: Belongs to the serpin family.

30608:CHRM2
gene id: 30608:CHRM2
uniprot id: A0A8C5XVH8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

30608:PACSIN1
gene id: 30608:PACSIN1
uniprot id: A0A8B7F2T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PACSIN family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytosol
messages: ruffle membrane
messages: synaptosome

30608:ACYP2
gene id: 30608:ACYP2
uniprot id: A0A8B7H9A8
uniprot id: A0A8B7HC21
names: Similarity
messages: Belongs to the acylphosphatase family.

30608:LOC105871458
gene id: 30608:LOC105871458
uniprot id: A0A8B7GCC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NIT2
gene id: 30608:NIT2
uniprot id: A0A8B7ETP3
uniprot id: A0A8B7EVL2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

30608:LOC105859376
gene id: 30608:LOC105859376
uniprot id: A0A8B7ETR9
uniprot id: A0A8B7EVR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

30608:CPA3
gene id: 30608:CPA3
uniprot id: A0A8C5YHP2
names: Similarity
messages: Belongs to the peptidase M14 family.

30608:ORC3
gene id: 30608:ORC3
uniprot id: A0A8B7FDL2
uniprot id: A0A8B7FDN1
uniprot id: A0A8B7FDT8
uniprot id: A0A8B7FEH3
uniprot id: A0A8B7X517
uniprot id: A0A8B7X677
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC3 family.
messages: Component of ORC, a complex composed of at least 6 subunits: ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase.
messages: Nucleus

30608:PLA2G4B
gene id: 30608:PLA2G4B
uniprot id: A0A8B7GGQ2
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

30608:VIPAS39
gene id: 30608:VIPAS39
uniprot id: A0A8B7EVC4
uniprot id: A0A8C5VEB1
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Early endosome
messages: Endosome
messages: Late endosome
messages: Vesicle

30608:NNMT
gene id: 30608:NNMT
uniprot id: A0A8B7F6N5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

30608:LOC105855523
gene id: 30608:LOC105855523
uniprot id: A0A8B7EF01
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:TJP3
gene id: 30608:TJP3
uniprot id: A0A8B7GQH3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: tight junction

30608:NLRP1
gene id: 30608:NLRP1
uniprot id: A0A8B7HD10
uniprot id: A0A8B7HD12
uniprot id: A0A8B7HD17
uniprot id: A0A8B7HD69
uniprot id: A0A8B7HFN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NLRP family.
messages: Inflammasome
messages: cytosol

30608:LOC105875309
gene id: 30608:LOC105875309
uniprot id: A0A8B7GW09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ACAP1
gene id: 30608:ACAP1
uniprot id: A0A8C5UZ60
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

30608:LOC105883398
gene id: 30608:LOC105883398
uniprot id: A0A8B7HX55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:VARS2
gene id: 30608:VARS2
uniprot id: A0A8B7X705
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

30608:TNF
gene id: 30608:TNF
uniprot id: A0A8B7ENJ8
uniprot id: A0A8B7ENP6
uniprot id: A0A8B7EQ28
uniprot id: A0A8B7EQP5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tumor necrosis factor family.
messages: Cell membrane
messages: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance. Plays a role in angiogenesis by inducing VEGF production synergistically with IL1B and IL6.
messages: Homotrimer. Interacts with SPPL2B.
messages: Membrane
messages: O-glycosylated; glycans contain galactose, N-acetylgalactosamine and N-acetylneuraminic acid.
messages: Secreted
messages: The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
messages: The membrane form, but not the soluble form, is phosphorylated on serine residues. Dephosphorylation of the membrane form occurs by binding to soluble TNFRSF1A/TNFR1.
messages: The soluble form derives from the membrane form by proteolytic processing. The membrane-bound form is further proteolytically processed by SPPL2A or SPPL2B through regulated intramembrane proteolysis producing TNF intracellular domains (ICD1 and ICD2) released in the cytosol and TNF C-domain 1 and C-domain 2 secreted into the extracellular space.

30608:AGPAT3
gene id: 30608:AGPAT3
uniprot id: A0A8C5Y213
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

30608:MED9
gene id: 30608:MED9
uniprot id: A0A8B7F6I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 9 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

30608:CACNG3
gene id: 30608:CACNG3
uniprot id: A0A8B7HF22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

30608:LOC105883429
gene id: 30608:LOC105883429
uniprot id: A0A8B7HV44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:POLR3GL
gene id: 30608:POLR3GL
uniprot id: A0A8B7G5B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

30608:CTNNA3
gene id: 30608:CTNNA3
uniprot id: A0A8B7G777
uniprot id: A0A8B7G7D1
uniprot id: A0A8B7G7W6
uniprot id: A0A8B7G8B9
names: Similarity
messages: Belongs to the vinculin/alpha-catenin family.

30608:POP5
gene id: 30608:POP5
uniprot id: A0A8C5UUH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

30608:STX10
gene id: 30608:STX10
uniprot id: A0A8B7I4V9
uniprot id: A0A8B7I6W5
uniprot id: A0A8B7WWT5
names: Subcellular Location Annotation
messages: Golgi apparatus membrane

30608:ENPP1
gene id: 30608:ENPP1
uniprot id: A0A8B7ED02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Secreted

30608:ARRB2
gene id: 30608:ARRB2
uniprot id: A0A8B7HDH6
uniprot id: A0A8C5XJS3
names: Similarity
messages: Belongs to the arrestin family.

30608:C17H16orf58
gene id: 30608:C17H16orf58
uniprot id: A0A8B7GBM9
uniprot id: A0A8C5UR93
names: Similarity
messages: Belongs to the RUS1 family.

30608:LOC105883362
gene id: 30608:LOC105883362
uniprot id: A0A8B7HX10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SPIN4
gene id: 30608:SPIN4
uniprot id: A0A8B7FTM7
names: Similarity
messages: Belongs to the SPIN/STSY family.

30608:SLC24A4
gene id: 30608:SLC24A4
uniprot id: A0A8B7EHF1
uniprot id: A0A8B7EHF2
uniprot id: A0A8B7EIE0
uniprot id: A0A8B7EJV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

30608:CENPE
gene id: 30608:CENPE
uniprot id: A0A8B7HC75
uniprot id: A0A8B7HC82
uniprot id: A0A8B7HC83
uniprot id: A0A8B7HC84
uniprot id: A0A8B7HEV8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:TMEM192
gene id: 30608:TMEM192
uniprot id: A0A8B7GRY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM192 family.
messages: Late endosome
messages: Lysosome membrane
messages: Membrane

30608:SIAH3
gene id: 30608:SIAH3
uniprot id: A0A8B7HKV8
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

30608:LOC109731230
gene id: 30608:LOC109731230
uniprot id: A0A8B7XE22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105858284
gene id: 30608:LOC105858284
uniprot id: A0A8B7EQR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

30608:ROPN1
gene id: 30608:ROPN1
uniprot id: A0A8C5YJD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ropporin family.
messages: flagellum

30608:CAPZB
gene id: 30608:CAPZB
uniprot id: A0A8B7HY32
uniprot id: A0A8B7HY47
uniprot id: A0A8B7HY48
uniprot id: A0A8C5XLF5
uniprot id: A0A8C5XME7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton
messages: sarcomere

30608:IER5
gene id: 30608:IER5
uniprot id: A0A8B7E9M4
names: Similarity
messages: Belongs to the IER family.

30608:S100G
gene id: 30608:S100G
uniprot id: A0A8B7HSK3
names: Similarity
messages: Belongs to the S-100 family.

30608:CDC42SE2
gene id: 30608:CDC42SE2
uniprot id: A0A8B7G6G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Interacts with CDC42 (in GTP-bound form). Interacts weakly with RAC1 and not at all with RHOA.
messages: Membrane
messages: Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.
messages: cytoskeleton

30608:SYNPR
gene id: 30608:SYNPR
uniprot id: A0A8B7GQA7
uniprot id: A0A8B7GQP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

30608:FGF7
gene id: 30608:FGF7
uniprot id: A0A8C5VT41
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

30608:ATG9A
gene id: 30608:ATG9A
uniprot id: A0A8B7ELQ9
uniprot id: A0A8B7ENQ5
uniprot id: A0A8B7ENR4
uniprot id: A0A8B7X8A5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

30608:GTPBP3
gene id: 30608:GTPBP3
uniprot id: A0A8B7WZ63
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.

30608:NOS1
gene id: 30608:NOS1
uniprot id: A0A8B7FSN4
uniprot id: A0A8C5Y2K7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.
messages: dendritic spine
messages: sarcolemma

30608:MS4A3
gene id: 30608:MS4A3
uniprot id: A0A8B7FTM8
names: Similarity
messages: Belongs to the MS4A family.

30608:CHRM4
gene id: 30608:CHRM4
uniprot id: A0A8B7I5U9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

30608:PRPS1
gene id: 30608:PRPS1
uniprot id: A0A8C5VJT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

30608:TLX3
gene id: 30608:TLX3
uniprot id: A0A8B7WVK1
uniprot id: A0A8C5XU18
names: Subcellular Location Annotation
messages: Nucleus

30608:KPNA2
gene id: 30608:KPNA2
uniprot id: A0A8B7WN56
names: Similarity
messages: Belongs to the importin alpha family.

30608:DLGAP3
gene id: 30608:DLGAP3
uniprot id: A0A8B7GDK3
names: Similarity
messages: Belongs to the SAPAP family.

30608:LOC105884121
gene id: 30608:LOC105884121
uniprot id: A0A8C6EIM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TP73
gene id: 30608:TP73
uniprot id: A0A8B7H4F0
uniprot id: A0A8B7H4I8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Cytoplasm
messages: Found in a complex with p53/TP53 and CABLES1.
messages: Nucleus
messages: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.

30608:KDM3B
gene id: 30608:KDM3B
uniprot id: A0A8B7F8V6
uniprot id: A0A8B7F904
uniprot id: A0A8C5Y6P3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM2 histone demethylase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.
messages: Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.
messages: Nucleus
messages: The JmjC domain and the C6-type zinc-finger are required for the demethylation activity.

30608:PQLC2
gene id: 30608:PQLC2
uniprot id: A0A8B7HY52
uniprot id: A0A8C5UWM8
names: Subcellular Location Annotation
messages: Membrane

30608:SUCNR1
gene id: 30608:SUCNR1
uniprot id: A0A8C5YI45
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:LOC105866478
gene id: 30608:LOC105866478
uniprot id: A0A8C5Y404
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

30608:LOC105862434
gene id: 30608:LOC105862434
uniprot id: A0A8B7F895
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105881941
gene id: 30608:LOC105881941
uniprot id: A0A8B7HNS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105861814
gene id: 30608:LOC105861814
uniprot id: A0A8B7WTZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P2X receptor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

30608:SOD1
gene id: 30608:SOD1
uniprot id: A0A8B7HGU6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

30608:TAF11
gene id: 30608:TAF11
uniprot id: A0A8B7F2U0
uniprot id: A0A8B7F2U1
names: Similarity
messages: Belongs to the TAF11 family.

30608:FOXF1
gene id: 30608:FOXF1
uniprot id: A0A8B7GC04
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105869923
gene id: 30608:LOC105869923
uniprot id: A0A8B7G5Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Cell membrane
messages: Membrane

30608:LOC105863767
gene id: 30608:LOC105863767
uniprot id: A0A8B7FEI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C2 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

30608:LOC105881940
gene id: 30608:LOC105881940
uniprot id: A0A8B7HNS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:GHSR
gene id: 30608:GHSR
uniprot id: A0A8B7ECI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NCF2
gene id: 30608:NCF2
uniprot id: A0A8B7WX75
names: Similarity
messages: Belongs to the NCF2/NOXA1 family.

30608:TACR2
gene id: 30608:TACR2
uniprot id: A0A8B7G729
uniprot id: A0A8B7G872
uniprot id: A0A8C5Y3F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105863106
gene id: 30608:LOC105863106
uniprot id: A0A8B7FB60
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:CHST8
gene id: 30608:CHST8
uniprot id: A0A8B7H551
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:ENPP3
gene id: 30608:ENPP3
uniprot id: A0A8B7EF68
names: Subcellular Location Annotation
messages: Secreted

30608:FAM83E
gene id: 30608:FAM83E
uniprot id: A0A8B7FLR1
names: Similarity
messages: Belongs to the FAM83 family.

30608:SLC13A3
gene id: 30608:SLC13A3
uniprot id: A0A8B7ETG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

30608:GPRIN2
gene id: 30608:GPRIN2
uniprot id: A0A8B7HZ08
uniprot id: A0A8B7HZ13
names: Function
messages: May be involved in neurite outgrowth.

30608:MARCH9
gene id: 30608:MARCH9
uniprot id: A0A8B7H7R4
names: Subcellular Location Annotation
messages: Membrane

30608:MDH2
gene id: 30608:MDH2
uniprot id: A0A8B7FZH9
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

30608:UNC5B
gene id: 30608:UNC5B
uniprot id: A0A8B7G6W8
uniprot id: A0A8B7G721
uniprot id: A0A8C5VGV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

30608:LOC105864424
gene id: 30608:LOC105864424
uniprot id: A0A8B7FH21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PHACTR2
gene id: 30608:PHACTR2
uniprot id: A0A8B7FHC0
uniprot id: A0A8B7FHD2
uniprot id: A0A8B7FHI3
uniprot id: A0A8B7FHJ3
uniprot id: A0A8B7FHK6
uniprot id: A0A8B7X511
uniprot id: A0A8B7X6X1
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

30608:FGFR1OP
gene id: 30608:FGFR1OP
uniprot id: A0A8B7X5E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP43 family.
messages: centriole
messages: cilium basal body

30608:LOC105871034
gene id: 30608:LOC105871034
uniprot id: A0A8B7GAL5
uniprot id: A0A8B7WPA4
uniprot id: A0A8C5XY97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

30608:CAPN9
gene id: 30608:CAPN9
uniprot id: A0A8C5VCC9
names: Similarity
messages: Belongs to the peptidase C2 family.

30608:KDM6B
gene id: 30608:KDM6B
uniprot id: A0A8B7H4Q4
uniprot id: A0A8B7H6T0
uniprot id: A0A8B7H711
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTX family.
messages: Nucleus

30608:NRG2
gene id: 30608:NRG2
uniprot id: A0A8B7F8R4
uniprot id: A0A8B7F8T0
uniprot id: A0A8B7F8W2
uniprot id: A0A8B7F980
uniprot id: A0A8B7F985
uniprot id: A0A8C5YCZ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:RAB3IL1
gene id: 30608:RAB3IL1
uniprot id: A0A8B7HAG7
uniprot id: A0A8B7HAG8
uniprot id: A0A8B7HAG9
uniprot id: A0A8B7HAH1
uniprot id: A0A8B7HAH2
uniprot id: A0A8B7HD78
names: Similarity
messages: Belongs to the SEC2 family.

30608:AMOTL2
gene id: 30608:AMOTL2
uniprot id: A0A8B7HYE0
uniprot id: A0A8B7I0G6
uniprot id: A0A8C5YHH3
names: Similarity
messages: Belongs to the angiomotin family.

30608:SPTLC3
gene id: 30608:SPTLC3
uniprot id: A0A8C5UMA8
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

30608:LOC105872974
gene id: 30608:LOC105872974
uniprot id: A0A8B7GJP8
uniprot id: A0A8B7GK51
uniprot id: A0A8B7WZ43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm
messages: nucleoplasm

30608:WRB
gene id: 30608:WRB
uniprot id: A0A8B7HIR6
uniprot id: A0A8B7HJS6
uniprot id: A0A8C5VAU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WRB/GET1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:ABCB4
gene id: 30608:ABCB4
uniprot id: A0A8B7XC68
uniprot id: A0A8B7XD78
uniprot id: A0A8B7XD84
uniprot id: A0A8B7XDW8
uniprot id: A0A8B7XDX3
uniprot id: A0A8B7XEF4
names: Subcellular Location Annotation
messages: Membrane

30608:IZUMO4
gene id: 30608:IZUMO4
uniprot id: A0A8B7F050
names: Similarity
messages: Belongs to the Izumo family.

30608:LOC105865729
gene id: 30608:LOC105865729
uniprot id: A0A8B7FNX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Odorant receptor.

30608:DEDD2
gene id: 30608:DEDD2
uniprot id: A0A8B7FX96
names: Subcellular Location Annotation
messages: nucleolus

30608:LDB2
gene id: 30608:LDB2
uniprot id: A0A8B7EFH5
names: Similarity
messages: Belongs to the LDB family.

30608:SH3BGRL2
gene id: 30608:SH3BGRL2
uniprot id: A0A8B7GNB6
names: Similarity
messages: Belongs to the SH3BGR family.

30608:LOC105884627
gene id: 30608:LOC105884627
uniprot id: A0A8B7X721
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Cytoplasm
messages: Nucleus

30608:S1PR5
gene id: 30608:S1PR5
uniprot id: A0A8B7I8I2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:FAM229A
gene id: 30608:FAM229A
uniprot id: A0A8C5YFB4
names: Similarity
messages: Belongs to the FAM229 family.

30608:ORAI3
gene id: 30608:ORAI3
uniprot id: A0A8C5VVF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

30608:SDR16C5
gene id: 30608:SDR16C5
uniprot id: A0A8C5VY38
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:PKN1
gene id: 30608:PKN1
uniprot id: A0A8B7FWK1
uniprot id: A0A8B7FWK2
uniprot id: A0A8B7FWR6
uniprot id: A0A8B7FXI5
uniprot id: A0A8C5XGB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cleavage furrow
messages: Midbody
messages: Nucleus

30608:ASB9
gene id: 30608:ASB9
uniprot id: A0A8B7HQV0
uniprot id: A0A8C5YAP4
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

30608:DFNB59
gene id: 30608:DFNB59
uniprot id: A0A8B7HTF0
names: Similarity
messages: Belongs to the gasdermin family.

30608:CKMT2
gene id: 30608:CKMT2
uniprot id: A0A8B7GHI4
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

30608:STX1A
gene id: 30608:STX1A
uniprot id: A0A8B7ERE6
uniprot id: A0A8B7WNV8
names: Similarity
messages: Belongs to the syntaxin family.

30608:LOC105865351
gene id: 30608:LOC105865351
uniprot id: A0A8C5XHM4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

30608:LOC105873314
gene id: 30608:LOC105873314
uniprot id: A0A8B7GKR6
uniprot id: A0A8B7GL30
uniprot id: A0A8B7XBU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105857953
gene id: 30608:LOC105857953
uniprot id: A0A8B7X741
names: Similarity
messages: Belongs to the KHDC1 family.

30608:SNRPA1
gene id: 30608:SNRPA1
uniprot id: A0A8B7GBT5
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

30608:LOC105879392
gene id: 30608:LOC105879392
uniprot id: A0A8B7HDN7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

30608:TMEM27
gene id: 30608:TMEM27
uniprot id: A0A8B7HSL8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:EIF4ENIF1
gene id: 30608:EIF4ENIF1
uniprot id: A0A8B7WTF4
names: Subcellular Location Annotation
messages: Cytoplasm

30608:RPS26
gene id: 30608:RPS26
uniprot id: A0A8B7X7N3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

30608:OPA1
gene id: 30608:OPA1
uniprot id: A0A8B7HF76
uniprot id: A0A8B7HF98
uniprot id: A0A8B7HFR1
uniprot id: A0A8C5YHL9
uniprot id: A0A8C5YJK0
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

30608:B4GALT7
gene id: 30608:B4GALT7
uniprot id: A0A8B7HXB6
uniprot id: A0A8B7HXC4
uniprot id: A0A8B7HZF4
uniprot id: A0A8B7HZX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

30608:XKR8
gene id: 30608:XKR8
uniprot id: A0A8B7FCU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

30608:SLC9A3R2
gene id: 30608:SLC9A3R2
uniprot id: A0A8B7EWQ8
uniprot id: A0A8B7EWR2
uniprot id: A0A8C5XG14
names: Function
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Endomembrane system
messages: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.

30608:XYLB
gene id: 30608:XYLB
uniprot id: A0A8B7FSQ6
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.

30608:LOC105880304
gene id: 30608:LOC105880304
uniprot id: A0A8B7WL73
names: Caution
names: Similarity
messages: Belongs to the DMBT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:WRN
gene id: 30608:WRN
uniprot id: A0A8B7WTE8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

30608:KRT20
gene id: 30608:KRT20
uniprot id: A0A8B7GEY3
names: Similarity
messages: Belongs to the intermediate filament family.

30608:LOC105881808
gene id: 30608:LOC105881808
uniprot id: A0A8B7FWL8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

30608:HIGD2A
gene id: 30608:HIGD2A
uniprot id: A0A8C5XW40
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

30608:ACBD5
gene id: 30608:ACBD5
uniprot id: A0A8B7WXC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.
messages: Belongs to the ATG37 family.
messages: Membrane
messages: Peroxisome membrane

30608:NSMCE4A
gene id: 30608:NSMCE4A
uniprot id: A0A8C5XYL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus
messages: telomere

30608:CCM2
gene id: 30608:CCM2
uniprot id: A0A8B7G8V4
uniprot id: A0A8B7G8V9
uniprot id: A0A8B7G8W0
uniprot id: A0A8B7G9Z7
uniprot id: A0A8B7GA02
uniprot id: A0A8C5W2A7
names: Similarity
messages: Belongs to the CCM2 family.

30608:CCL17
gene id: 30608:CCL17
uniprot id: A0A8B7FF65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

30608:PKN3
gene id: 30608:PKN3
uniprot id: A0A8B7XBD8
uniprot id: A0A8C5V5N7
uniprot id: A0A8C5XIS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Nucleus

30608:LOC109729691
gene id: 30608:LOC109729691
uniprot id: A0A8B7WQH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

30608:LOC105859693
gene id: 30608:LOC105859693
uniprot id: A0A8B7EV86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:RPL13A
gene id: 30608:RPL13A
uniprot id: A0A8B7FM42
uniprot id: A0A8C5VE16
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

30608:NFE2L1
gene id: 30608:NFE2L1
uniprot id: A0A8B7GFX7
uniprot id: A0A8B7GG91
uniprot id: A0A8B7GG92
uniprot id: A0A8B7WNG9
uniprot id: A0A8B7WNH3
uniprot id: A0A8B7WNH5
uniprot id: A0A8B7WNK4
uniprot id: A0A8B7WPS3
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

30608:PTK2
gene id: 30608:PTK2
uniprot id: A0A8B7XBT7
names: Subcellular Location Annotation
messages: Cell membrane
messages: cell cortex
messages: focal adhesion

30608:PSD2
gene id: 30608:PSD2
uniprot id: A0A8B7F8R8
uniprot id: A0A8B7F8R9
uniprot id: A0A8B7F8W7
names: Subcellular Location Annotation
messages: Membrane
messages: ruffle membrane

30608:LOC105883352
gene id: 30608:LOC105883352
uniprot id: A0A8B7HX17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CETN2
gene id: 30608:CETN2
uniprot id: A0A8B7I113
names: Similarity
messages: Belongs to the centrin family.

30608:DNAH6
gene id: 30608:DNAH6
uniprot id: A0A8B7H0T9
uniprot id: A0A8B7X274
uniprot id: A0A8B7X2R5
uniprot id: A0A8B7X3J0
uniprot id: A0A8B7X3Y9
names: Similarity
messages: Belongs to the dynein heavy chain family.

30608:FGF1
gene id: 30608:FGF1
uniprot id: A0A8B7F8K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

30608:ITGAV
gene id: 30608:ITGAV
uniprot id: A0A8B7HDD1
uniprot id: A0A8C5W784
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

30608:APOC4
gene id: 30608:APOC4
uniprot id: A0A8B7G3V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C4 family.
messages: May participate in lipoprotein metabolism.
messages: Secreted

30608:PSMB9
gene id: 30608:PSMB9
uniprot id: A0A8B7I765
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

30608:LOC105870080
gene id: 30608:LOC105870080
uniprot id: A0A8B7G6F4
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

30608:SDF4
gene id: 30608:SDF4
uniprot id: A0A8B7H5X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Golgi apparatus lumen

30608:LOC105875016
gene id: 30608:LOC105875016
uniprot id: A0A8B7X9K8
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

30608:TNFSF9
gene id: 30608:TNFSF9
uniprot id: A0A8B7G4S8
names: Similarity
messages: Belongs to the tumor necrosis factor family.

30608:DHFR
gene id: 30608:DHFR
uniprot id: A0A8B7GHH5
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

30608:LOC105859551
gene id: 30608:LOC105859551
uniprot id: A0A8B7WUU4
names: Similarity
messages: Belongs to the urocanase family.

30608:CERCAM
gene id: 30608:CERCAM
uniprot id: A0A8B7GVT5
uniprot id: A0A8B7GXG0
uniprot id: A0A8B7XBD5
uniprot id: A0A8B7XDL1
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

30608:CLDN1
gene id: 30608:CLDN1
uniprot id: A0A8C5YJB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

30608:STAB1
gene id: 30608:STAB1
uniprot id: A0A8B7GUD0
uniprot id: A0A8B7WLV9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:CLDN7
gene id: 30608:CLDN7
uniprot id: A0A8C5Y660
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

30608:FOXN1
gene id: 30608:FOXN1
uniprot id: A0A8B7EMQ7
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105858732
gene id: 30608:LOC105858732
uniprot id: A0A8B7ET00
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:DEFB133
gene id: 30608:DEFB133
uniprot id: A0A8B7X747
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

30608:MYO18B
gene id: 30608:MYO18B
uniprot id: A0A8B7FT11
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:RAD18
gene id: 30608:RAD18
uniprot id: A0A8B7G278
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD18 family.
messages: Nucleus

30608:DHPS
gene id: 30608:DHPS
uniprot id: A0A8C5XN46
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

30608:LOC105879919
gene id: 30608:LOC105879919
uniprot id: A0A8B7HGP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

30608:CCR6
gene id: 30608:CCR6
uniprot id: A0A8B7H6Z7
uniprot id: A0A8B7H6Z9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:LOC105861303
gene id: 30608:LOC105861303
uniprot id: A0A8B7F448
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MECP2
gene id: 30608:MECP2
uniprot id: A0A8C5VU15
names: Function
names: Subcellular Location Annotation
messages: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
messages: Nucleus

30608:OTP
gene id: 30608:OTP
uniprot id: A0A8B7EHD3
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105885541
gene id: 30608:LOC105885541
uniprot id: A0A8B7I533
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:RPS3
gene id: 30608:RPS3
uniprot id: A0A8C5XGU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: spindle

30608:HNRNPF
gene id: 30608:HNRNPF
uniprot id: A0A8B7HC29
names: Subcellular Location Annotation
messages: nucleoplasm

30608:PDE10A
gene id: 30608:PDE10A
uniprot id: A0A8B7H6X2
uniprot id: A0A8B7H6X3
uniprot id: A0A8B7H6X8
uniprot id: A0A8B7H6Y0
uniprot id: A0A8B7H6Z8
uniprot id: A0A8B7H9F3
uniprot id: A0A8B7X574
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

30608:CCT2
gene id: 30608:CCT2
uniprot id: A0A8C5XUN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

30608:GPX6
gene id: 30608:GPX6
uniprot id: A0A8B7EQW4
names: Similarity
messages: Belongs to the glutathione peroxidase family.

30608:HSD17B2
gene id: 30608:HSD17B2
uniprot id: A0A8B7EW51
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:ENSA
gene id: 30608:ENSA
uniprot id: A0A8B7GJ93
uniprot id: A0A8B7GJ96
uniprot id: A0A8B7GJL4
uniprot id: A0A8C5XNB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

30608:LOC105868191
gene id: 30608:LOC105868191
uniprot id: A0A8B7WVP1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

30608:TCP11
gene id: 30608:TCP11
uniprot id: A0A8B7F2S8
uniprot id: A0A8C5VM98
names: Similarity
messages: Belongs to the TCP11 family.

30608:MPV17L
gene id: 30608:MPV17L
uniprot id: A0A8B7I751
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

30608:TTC3
gene id: 30608:TTC3
uniprot id: A0A8B7HML5
names: Subcellular Location Annotation
messages: Cytoplasm

30608:AGAP1
gene id: 30608:AGAP1
uniprot id: A0A8B7X7C6
uniprot id: A0A8B7X7D1
uniprot id: A0A8B7X7D2
uniprot id: A0A8B7X822
uniprot id: A0A8B7X825
uniprot id: A0A8B7X922
uniprot id: A0A8B7X9D3
uniprot id: A0A8B7X9D8
uniprot id: A0A8C5UWZ0
names: Similarity
messages: Belongs to the centaurin gamma-like family.

30608:FAM168A
gene id: 30608:FAM168A
uniprot id: A0A8B7EY85
uniprot id: A0A8B7X3T8
uniprot id: A0A8C5Y5Z3
names: Similarity
messages: Belongs to the FAM168 family.

30608:SLC25A31
gene id: 30608:SLC25A31
uniprot id: A0A8B7I6J4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

30608:SFRP1
gene id: 30608:SFRP1
uniprot id: A0A8B7H8E6
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:TEX13B
gene id: 30608:TEX13B
uniprot id: A0A8B7FD05
names: Similarity
messages: Belongs to the TEX13 family.

30608:LOC105864631
gene id: 30608:LOC105864631
uniprot id: A0A8B7FHR8
uniprot id: A0A8B7FHS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CIAPIN1
gene id: 30608:CIAPIN1
uniprot id: A0A8B7FEZ1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with NDOR1. Interacts with CHCHD4.
messages: Nucleus
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial CHCHD4/MIA40-GFER/ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

30608:MYC
gene id: 30608:MYC
uniprot id: A0A8B7HSC7
uniprot id: A0A8C5VIX8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.
messages: nucleolus
messages: nucleoplasm

30608:LOC105862435
gene id: 30608:LOC105862435
uniprot id: A0A8B7F8D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TNNT2
gene id: 30608:TNNT2
uniprot id: A0A8B7EX28
uniprot id: A0A8B7EX37
uniprot id: A0A8B7EZ01
uniprot id: A0A8B7WX46
uniprot id: A0A8B7WXG9
uniprot id: A0A8B7WXX5
uniprot id: A0A8B7WYV6
uniprot id: A0A8B7WYV9
uniprot id: A0A8C5W1V0
uniprot id: A0A8C5YA06
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

30608:FAM32A
gene id: 30608:FAM32A
uniprot id: A0A8B7FXW4
names: Similarity
messages: Belongs to the FAM32 family.

30608:LOC105867927
gene id: 30608:LOC105867927
uniprot id: A0A8B7FWV5
uniprot id: A0A8B7FXL8
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:VEGFD
gene id: 30608:VEGFD
uniprot id: A0A8B7X075
uniprot id: A0A8C5UMG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

30608:MAPK15
gene id: 30608:MAPK15
uniprot id: A0A8B7G1B4
uniprot id: A0A8B7G1B9
uniprot id: A0A8B7G1C4
uniprot id: A0A8B7G277
uniprot id: A0A8B7G282
uniprot id: A0A8B7G2Q4
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

30608:KCNH4
gene id: 30608:KCNH4
uniprot id: A0A8B7EU11
uniprot id: A0A8B7EU12
uniprot id: A0A8B7EVZ8
uniprot id: A0A8C5XVE5
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

30608:GLOD4
gene id: 30608:GLOD4
uniprot id: A0A8B7EMC9
names: Similarity
messages: Belongs to the glyoxalase I family.

30608:CTSK
gene id: 30608:CTSK
uniprot id: A0A8C5UTB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

30608:HEG1
gene id: 30608:HEG1
uniprot id: A0A8B7HFN2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105855558
gene id: 30608:LOC105855558
uniprot id: A0A8C5URW6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

30608:ENTPD3
gene id: 30608:ENTPD3
uniprot id: A0A8B7GRE4
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

30608:NPM1
gene id: 30608:NPM1
uniprot id: A0A8C5YAS8
uniprot id: A0A8C6EHK9
names: Similarity
messages: Belongs to the nucleoplasmin family.

30608:SGSM1
gene id: 30608:SGSM1
uniprot id: A0A8B7FTI7
uniprot id: A0A8B7WT56
uniprot id: A0A8C6EKQ7
names: Similarity
messages: Belongs to the RUTBC family.

30608:LOC105876370
gene id: 30608:LOC105876370
uniprot id: A0A8B7H0E6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:NCL
gene id: 30608:NCL
uniprot id: A0A8C5UR88
names: Function
names: Subcellular Location Annotation
messages: Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.
messages: nucleolus

30608:LOC105869359
gene id: 30608:LOC105869359
uniprot id: A0A8B7WWI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:LOC105867899
gene id: 30608:LOC105867899
uniprot id: A0A8B7FWJ3
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:OSBPL2
gene id: 30608:OSBPL2
uniprot id: A0A8B7GXM8
uniprot id: A0A8B7GXS0
uniprot id: A0A8B7GZH6
names: Similarity
messages: Belongs to the OSBP family.

30608:CLDN9
gene id: 30608:CLDN9
uniprot id: A0A8C5UT47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

30608:DYSF
gene id: 30608:DYSF
uniprot id: A0A8B7FBI5
uniprot id: A0A8B7FBJ1
uniprot id: A0A8B7FBJ2
uniprot id: A0A8B7FBJ6
uniprot id: A0A8B7FBK2
uniprot id: A0A8B7FBK3
uniprot id: A0A8B7FBK4
uniprot id: A0A8B7FBK7
uniprot id: A0A8B7FBK8
uniprot id: A0A8B7FBL0
uniprot id: A0A8B7FBL3
uniprot id: A0A8B7FBL5
uniprot id: A0A8B7FBP4
uniprot id: A0A8B7FBQ8
uniprot id: A0A8B7FBR5
uniprot id: A0A8B7FBS1
uniprot id: A0A8B7FC78
uniprot id: A0A8B7FC84
uniprot id: A0A8B7FC89
uniprot id: A0A8B7FC95
uniprot id: A0A8C5VAV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferlin family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

30608:PTX3
gene id: 30608:PTX3
uniprot id: A0A8B7EKG4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:CPPED1
gene id: 30608:CPPED1
uniprot id: A0A8B7WNL9
uniprot id: A0A8B7WNR1
names: Function
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. CPPED1 family.
messages: Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.

30608:SCD
gene id: 30608:SCD
uniprot id: A0A8C5XY19
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

30608:CFAP97
gene id: 30608:CFAP97
uniprot id: A0A8B7HTJ4
names: Similarity
messages: Belongs to the CFAP97 family.

30608:LOC105870495
gene id: 30608:LOC105870495
uniprot id: A0A8B7WPK8
names: Similarity
messages: Belongs to the Bcl-2 family.

30608:MSX1
gene id: 30608:MSX1
uniprot id: A0A8B7EKP0
names: Subcellular Location Annotation
messages: Nucleus

30608:IPO11
gene id: 30608:IPO11
uniprot id: A0A8B7HP01
uniprot id: A0A8B7HP11
uniprot id: A0A8B7HP12
uniprot id: A0A8B7HRF4
names: Subcellular Location Annotation
messages: Cytoplasm

30608:LOC105861316
gene id: 30608:LOC105861316
uniprot id: A0A8B7F455
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TATDN2
gene id: 30608:TATDN2
uniprot id: A0A8B7G268
uniprot id: A0A8B7G271
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

30608:TRMT13
gene id: 30608:TRMT13
uniprot id: A0A8B7F805
uniprot id: A0A8B7F808
uniprot id: A0A8B7F8A9
names: Function
names: Similarity
messages: Belongs to the methyltransferase TRM13 family.
messages: tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

30608:SLC9A1
gene id: 30608:SLC9A1
uniprot id: A0A8B7FDA5
uniprot id: A0A8B7FE51
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

30608:RXRB
gene id: 30608:RXRB
uniprot id: A0A8B7I745
uniprot id: A0A8B7I959
uniprot id: A0A8B7IAG3
uniprot id: A0A8B7X5X4
uniprot id: A0A8C5VJL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Nucleus

30608:STC1
gene id: 30608:STC1
uniprot id: A0A8C5VMQ8
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

30608:FUT2
gene id: 30608:FUT2
uniprot id: A0A8B7FME7
uniprot id: A0A8B7FMN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 11 family.
messages: Golgi stack membrane
messages: Membrane

30608:LOC105859893
gene id: 30608:LOC105859893
uniprot id: A0A8B7EWB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

30608:ACAT2
gene id: 30608:ACAT2
uniprot id: A0A8B7G131
uniprot id: A0A8C5XCP2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

30608:LOC105860316
gene id: 30608:LOC105860316
uniprot id: A0A8B7EY74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105859891
gene id: 30608:LOC105859891
uniprot id: A0A8B7EYA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC109729580
gene id: 30608:LOC109729580
uniprot id: A0A8B7WP33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

30608:OSBPL8
gene id: 30608:OSBPL8
uniprot id: A0A8B7FCA8
uniprot id: A0A8B7FCA9
uniprot id: A0A8B7FCB1
uniprot id: A0A8B7FCG7
uniprot id: A0A8B7FD18
uniprot id: A0A8C5XNX6
names: Similarity
messages: Belongs to the OSBP family.

30608:SMC6
gene id: 30608:SMC6
uniprot id: A0A8B7FQZ8
names: Subcellular Location Annotation
messages: Chromosome

30608:GMDS
gene id: 30608:GMDS
uniprot id: A0A8B7GLN5
uniprot id: A0A8B7GLN8
uniprot id: A0A8B7GM01
uniprot id: A0A8B7GM07
uniprot id: A0A8B7GMY9
uniprot id: A0A8C5Y9V1
uniprot id: A0A8C5YDZ0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

30608:HNRNPA2B1
gene id: 30608:HNRNPA2B1
uniprot id: A0A8B7GYP0
uniprot id: A0A8B7H0L5
names: Subcellular Location Annotation
messages: Cytoplasmic granule

30608:LOC105864466
gene id: 30608:LOC105864466
uniprot id: A0A8B7FIF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SLC23A2
gene id: 30608:SLC23A2
uniprot id: A0A8B7FPW4
uniprot id: A0A8C5Y8I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

30608:KRT35
gene id: 30608:KRT35
uniprot id: A0A8C5V072
names: Similarity
messages: Belongs to the intermediate filament family.

30608:TMEM9
gene id: 30608:TMEM9
uniprot id: A0A8B7EX15
names: Similarity
messages: Belongs to the TMEM9 family.

30608:PEX10
gene id: 30608:PEX10
uniprot id: A0A8B7H665
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Membrane
messages: Peroxisome membrane

30608:SEMA5A
gene id: 30608:SEMA5A
uniprot id: A0A8B7I6K8
uniprot id: A0A8B7I9V2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:VEPH1
gene id: 30608:VEPH1
uniprot id: A0A8B7EKS5
uniprot id: A0A8B7ELQ5
names: Similarity
messages: Belongs to the MELT/VEPH family.

30608:MLST8
gene id: 30608:MLST8
uniprot id: A0A8B7EUZ0
uniprot id: A0A8B7EWX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LST8 family.
messages: Cytoplasm
messages: Part of the mammalian target of rapamycin complex 1 (mTORC1) which contains MTOR, MLST8, RPTOR, AKT1S1/PRAS40 and DEPTOR. mTORC1 binds to and is inhibited by FKBP12-rapamycin. Part of the mammalian target of rapamycin complex 2 (mTORC2) which contains MTOR, MLST8, PRR5, RICTOR, MAPKAP1 and DEPTOR. Contrary to mTORC1, mTORC2 does not bind to and is not sensitive to FKBP12-rapamycin. Interacts directly with MTOR and RPTOR. Interacts with RHEB. Interacts with MEAK7. Interacts with SIK3.
messages: Subunit of both mTORC1 and mTORC2, which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC1 phosphorylates and activates S6K1, which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation. Within mTORC1, LST8 interacts directly with MTOR and enhances its kinase activity. In nutrient-poor conditions, stabilizes the MTOR-RPTOR interaction and favors RPTOR-mediated inhibition of MTOR activity. mTORC2 is also activated by growth factors, but seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1. mTORC2 also modulates the phosphorylation of PRKCA.

30608:N6AMT1
gene id: 30608:N6AMT1
uniprot id: A0A8B7GBY4
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

30608:LOC105884146
gene id: 30608:LOC105884146
uniprot id: A0A8B7HYK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:VPS37D
gene id: 30608:VPS37D
uniprot id: A0A8B7ERJ3
uniprot id: A0A8C5XGJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

30608:TLE3
gene id: 30608:TLE3
uniprot id: A0A8B7GL87
uniprot id: A0A8B7GL92
uniprot id: A0A8B7GL94
uniprot id: A0A8B7GL97
uniprot id: A0A8B7GLA0
uniprot id: A0A8B7GLA5
uniprot id: A0A8B7GLJ9
uniprot id: A0A8B7GLK4
uniprot id: A0A8B7GLU4
uniprot id: A0A8B7GLU9
uniprot id: A0A8B7GLV5
uniprot id: A0A8B7GMH6
uniprot id: A0A8B7GMI3
uniprot id: A0A8B7GMI8
uniprot id: A0A8B7GMJ2
uniprot id: A0A8C6ECK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

30608:TM4SF20
gene id: 30608:TM4SF20
uniprot id: A0A8B7FAF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

30608:LOC105868273
gene id: 30608:LOC105868273
uniprot id: A0A8B7FXW0
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

30608:PCBD2
gene id: 30608:PCBD2
uniprot id: A0A8B7WRT0
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

30608:DNTT
gene id: 30608:DNTT
uniprot id: A4PCE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Nucleus
messages: Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator.

30608:LOC105859236
gene id: 30608:LOC105859236
uniprot id: A0A8C5W0E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CDKL4
gene id: 30608:CDKL4
uniprot id: A0A8B7X8W0
uniprot id: A0A8B7X8W1
uniprot id: A0A8B7X9K7
uniprot id: A0A8B7XAI9
uniprot id: A0A8B7XAX2
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:LOC109729810
gene id: 30608:LOC109729810
uniprot id: A0A8B7WSM2
names: Subcellular Location Annotation
messages: Secreted

30608:LOC105866000
gene id: 30608:LOC105866000
uniprot id: A0A8B7FP72
uniprot id: A0A8B7FPG9
uniprot id: A0A8B7FQA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

30608:EXOC3L2
gene id: 30608:EXOC3L2
uniprot id: A0A8B7G3Z2
names: Similarity
messages: Belongs to the SEC6 family.

30608:MSR1
gene id: 30608:MSR1
uniprot id: A0A8B7G1G5
names: Subcellular Location Annotation
messages: Membrane

30608:DHRS11
gene id: 30608:DHRS11
uniprot id: A0A8B7HGN3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:GPRIN3
gene id: 30608:GPRIN3
uniprot id: A0A8B7H2C2
names: Function
messages: May be involved in neurite outgrowth.

30608:LOC105864758
gene id: 30608:LOC105864758
uniprot id: A0A8B7FIE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Odorant receptor.

30608:CUX2
gene id: 30608:CUX2
uniprot id: A0A8B7WTK0
uniprot id: A0A8B7WTR3
uniprot id: A0A8B7WTV8
uniprot id: A0A8B7WV45
uniprot id: A0A8C5XLK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

30608:RPS29
gene id: 30608:RPS29
uniprot id: A0A8C5YBP3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Component of the 40S small ribosomal subunit.

30608:NUDT12
gene id: 30608:NUDT12
uniprot id: A0A8B7XEA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Cytoplasmic granule
messages: Peroxisome

30608:LOC105869724
gene id: 30608:LOC105869724
uniprot id: A0A8B7G4U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CDC42EP3
gene id: 30608:CDC42EP3
uniprot id: A0A8C5Y426
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

30608:LOC105864634
gene id: 30608:LOC105864634
uniprot id: A0A8B7FHV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MS4A13
gene id: 30608:MS4A13
uniprot id: A0A8B7FTJ7
names: Similarity
messages: Belongs to the MS4A family.

30608:BMP6
gene id: 30608:BMP6
uniprot id: A0A8B7FK78
names: Similarity
messages: Belongs to the TGF-beta family.

30608:GRIK1
gene id: 30608:GRIK1
uniprot id: A0A8B7HGW3
uniprot id: A0A8B7HGW8
uniprot id: A0A8B7HGZ7
uniprot id: A0A8B7HHN2
uniprot id: A0A8B7HJJ0
uniprot id: A0A8B7WY84
uniprot id: A0A8B7WY86
uniprot id: A0A8B7WYQ1
uniprot id: A0A8B7WZ57
uniprot id: A0A8C5XJU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

30608:LOC105879037
gene id: 30608:LOC105879037
uniprot id: A0A8B7WXC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

30608:SESN3
gene id: 30608:SESN3
uniprot id: A0A8B7EXQ2
uniprot id: A0A8B7X3F9
uniprot id: A0A8B7X4Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

30608:ALKAL1
gene id: 30608:ALKAL1
uniprot id: A0A8B7I3Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

30608:LOC105876243
gene id: 30608:LOC105876243
uniprot id: A0A8B7GZZ3
uniprot id: A0A8B7WXS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

30608:RPL18A
gene id: 30608:RPL18A
uniprot id: A0A8B7ECZ5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

30608:ITGB4
gene id: 30608:ITGB4
uniprot id: A0A8B7HBU9
uniprot id: A0A8C5VHF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

30608:OGFR
gene id: 30608:OGFR
uniprot id: A0A8B7GXN7
uniprot id: A0A8B7GXQ1
uniprot id: A0A8B7GZI6
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

30608:LOC105871610
gene id: 30608:LOC105871610
uniprot id: A0A8B7GDJ0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

30608:RPL26
gene id: 30608:RPL26
uniprot id: A0A8C5V0F5
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

30608:LOC105877013
gene id: 30608:LOC105877013
uniprot id: A0A8B7WUF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

30608:MRPL20
gene id: 30608:MRPL20
uniprot id: A0A8C5Y9X1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.

30608:ITK
gene id: 30608:ITK
uniprot id: A0A8B7HKU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cytoplasm

30608:AK5
gene id: 30608:AK5
uniprot id: A0A8C5UPU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylate kinase family.
messages: Cytoplasm

30608:KIF18B
gene id: 30608:KIF18B
uniprot id: A0A8B7HVW6
uniprot id: A0A8B7HVY1
uniprot id: A0A8B7HY16
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:DUT
gene id: 30608:DUT
uniprot id: A0A8B7G965
uniprot id: A0A8B7GA97
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

30608:NDST1
gene id: 30608:NDST1
uniprot id: A0A8B7I8B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

30608:FAM122C
gene id: 30608:FAM122C
uniprot id: A0A8B7GCW1
uniprot id: A0A8B7GCY7
uniprot id: A0A8B7WZ44
names: Similarity
messages: Belongs to the FAM122 family.

30608:USP33
gene id: 30608:USP33
uniprot id: A0A8B7HXV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: centrosome
messages: perinuclear region

30608:RNASE6
gene id: 30608:RNASE6
uniprot id: A0A8B7FHU9
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

30608:KLHL21
gene id: 30608:KLHL21
uniprot id: A0A8B7I7I0
names: Subcellular Location Annotation
messages: spindle

30608:C21H12orf49
gene id: 30608:C21H12orf49
uniprot id: A0A8B7FSN7
uniprot id: A0A8C5V4Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPRING family.
messages: Golgi apparatus membrane
messages: Membrane

30608:FLVCR1
gene id: 30608:FLVCR1
uniprot id: A0A8B7HIF0
names: Subcellular Location Annotation
messages: Membrane

30608:SLC35E1
gene id: 30608:SLC35E1
uniprot id: A0A8B7FWS3
names: Subcellular Location Annotation
messages: Membrane

30608:DERL2
gene id: 30608:DERL2
uniprot id: A0A8B7HD19
uniprot id: A0A8B7HD80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:PLPP1
gene id: 30608:PLPP1
uniprot id: A0A8B7H493
uniprot id: A0A8B7H4A0
uniprot id: A0A8B7H4D7
uniprot id: A0A8C5XY85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

30608:LOC105880607
gene id: 30608:LOC105880607
uniprot id: A0A8B7HIR5
uniprot id: A0A8B7WXZ1
names: Similarity
messages: Belongs to the SH3BGR family.

30608:IL31RA
gene id: 30608:IL31RA
uniprot id: A0A8B7H469
uniprot id: A0A8B7H477
uniprot id: A0A8B7H6F9
names: Subcellular Location Annotation
messages: Membrane

30608:WNT2
gene id: 30608:WNT2
uniprot id: A0A8B7G368
uniprot id: Q2QL85
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity).
messages: Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.
messages: Secreted
messages: extracellular matrix

30608:FES
gene id: 30608:FES
uniprot id: A0A8B7G8J2
uniprot id: A0A8B7G974
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

30608:CLCN4
gene id: 30608:CLCN4
uniprot id: A0A8B7HTD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

30608:C8H2orf70
gene id: 30608:C8H2orf70
uniprot id: A0A8C5Y8J1
names: Similarity
messages: Belongs to the CIMIP2 family.

30608:LMOD3
gene id: 30608:LMOD3
uniprot id: A0A8B7FY77
names: Subcellular Location Annotation
messages: cytoskeleton

30608:CHD1L
gene id: 30608:CHD1L
uniprot id: A0A8B7G599
uniprot id: A0A8B7G5Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

30608:CSNK2B
gene id: 30608:CSNK2B
uniprot id: A0A8B7ENN1
uniprot id: A0A8B7EQ11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling.
messages: Tetramer of two alpha and two beta subunits.

30608:LOC105880435
gene id: 30608:LOC105880435
uniprot id: A0A8B7HI23
names: Similarity
messages: Belongs to the semenogelin family.

30608:STX16
gene id: 30608:STX16
uniprot id: A0A8B7GRL4
uniprot id: A0A8B7GRL9
uniprot id: A0A8B7GRX6
uniprot id: A0A8B7GRY2
uniprot id: A0A8B7GTA3
uniprot id: A0A8C5V6D1
uniprot id: A0A8C5VIA5
names: Similarity
messages: Belongs to the syntaxin family.

30608:FAM76A
gene id: 30608:FAM76A
uniprot id: A0A8C5VFG8
uniprot id: A0A8C5VZU1
names: Similarity
messages: Belongs to the FAM76 family.

30608:NT5DC3
gene id: 30608:NT5DC3
uniprot id: A0A8B7GX63
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

30608:PCBD1
gene id: 30608:PCBD1
uniprot id: A0A8B7G6X2
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

30608:MS4A7
gene id: 30608:MS4A7
uniprot id: A0A8B7FTP2
uniprot id: A0A8B7FUJ2
names: Similarity
messages: Belongs to the MS4A family.

30608:ABI3
gene id: 30608:ABI3
uniprot id: A0A8B7I321
uniprot id: A0A8C5UWW9
names: Similarity
messages: Belongs to the ABI family.

30608:LOC105878641
gene id: 30608:LOC105878641
uniprot id: A0A8C5V176
names: Similarity
messages: Belongs to the peptidase A1 family.

30608:CRYZ
gene id: 30608:CRYZ
uniprot id: A0A8B7I008
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

30608:CHD7
gene id: 30608:CHD7
uniprot id: A0A8B7EI21
uniprot id: A0A8C5UN33
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

30608:COPE
gene id: 30608:COPE
uniprot id: A0A8B7WX26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPE family.
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated with ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

30608:LOC105856136
gene id: 30608:LOC105856136
uniprot id: A0A8C5UV24
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

30608:HMBOX1
gene id: 30608:HMBOX1
uniprot id: A0A8B7H3P8
uniprot id: A0A8B7H3Q2
uniprot id: A0A8B7H3Q3
uniprot id: A0A8B7H3Q7
uniprot id: A0A8B7H3Q8
uniprot id: A0A8B7H3U6
uniprot id: A0A8B7H3V1
uniprot id: A0A8B7H5X2
uniprot id: A0A8B7H5X8
uniprot id: A0A8B7WS08
uniprot id: A0A8C5XVW1
names: Subcellular Location Annotation
messages: Nucleus

30608:XRCC4
gene id: 30608:XRCC4
uniprot id: A0A8C5VFH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XRCC4 subfamily.
messages: Nucleus

30608:LOC105882329
gene id: 30608:LOC105882329
uniprot id: A0A8B7HS39
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:WNT11
gene id: 30608:WNT11
uniprot id: A0A8B7F0K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

30608:BOLA1
gene id: 30608:BOLA1
uniprot id: A0A8B7FLN0
names: Similarity
messages: Belongs to the BolA/IbaG family.

30608:PKD1L2
gene id: 30608:PKD1L2
uniprot id: A0A8B7F3Q3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:ROR1
gene id: 30608:ROR1
uniprot id: A0A8B7GI83
uniprot id: A0A8B7GIL7
uniprot id: A0A8C5W2Z5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:ELAVL4
gene id: 30608:ELAVL4
uniprot id: A0A8B7H5B9
uniprot id: A0A8B7H5C0
uniprot id: A0A8B7H5C3
uniprot id: A0A8B7H5C4
uniprot id: A0A8B7H5C8
uniprot id: A0A8B7H5C9
uniprot id: A0A8B7H5D3
uniprot id: A0A8B7H5F4
uniprot id: A0A8B7H7P1
uniprot id: A0A8B7H7Q2
uniprot id: A0A8B7XBC6
uniprot id: A0A8B7XBD4
uniprot id: A0A8B7XDK6
uniprot id: A0A8C5W3C0
uniprot id: A0A8C5Y0M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm
messages: Perikaryon
messages: axon
messages: dendrite
messages: growth cone

30608:MYCN
gene id: 30608:MYCN
uniprot id: A0A8B7X910
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

30608:LOC105883161
gene id: 30608:LOC105883161
uniprot id: A0A8B7HW76
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

30608:SLC31A1
gene id: 30608:SLC31A1
uniprot id: A0A8C5VYJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

30608:MYRFL
gene id: 30608:MYRFL
uniprot id: A0A8B7I0T7
uniprot id: A0A8B7I0T9
uniprot id: A0A8B7I2W7
uniprot id: A0A8B7X723
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRF family.
messages: Membrane

30608:MGAT5B
gene id: 30608:MGAT5B
uniprot id: A0A8C5VK04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:LOC105860375
gene id: 30608:LOC105860375
uniprot id: A0A8B7F0G0
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

30608:PTGES3
gene id: 30608:PTGES3
uniprot id: A0A8B7FLQ0
uniprot id: A0A8B7FLT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p23/wos2 family.
messages: Cytoplasm
messages: Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation.
messages: Forms a complex with HSP70, HSP90 and other chaperones.

30608:ILKAP
gene id: 30608:ILKAP
uniprot id: A0A8B7X8Y1
names: Similarity
messages: Belongs to the PP2C family.

30608:TERT
gene id: 30608:TERT
uniprot id: A0A8B7H0J1
uniprot id: A0A8B7H0Q8
uniprot id: A0A8B7H2J5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension. More active on substrates containing 2 or 3 telomeric repeats. Telomerase activity is regulated by a number of factors including telomerase complex-associated proteins, chaperones and polypeptide modifiers. Modulates Wnt signaling. Plays important roles in aging and antiapoptosis.
messages: The RNA-interacting domain 1 (RD1)/N-terminal extension (NTE) is required for interaction with the pseudoknot-template domain of each of TERC dimers. It contains anchor sites that bind primer nucleotides upstream of the RNA-DNA hybrid and is thus an essential determinant of repeat addition processivity.
messages: The RNA-interacting domain 2 (RD2) is essential for both interaction with the CR4-CR5 domain of TERC and for DNA synthesis.
messages: The primer grip sequence in the RT domain is required for telomerase activity and for stable association with short telomeric primers.
messages: nucleolus
messages: nucleoplasm
messages: telomere

30608:GDF7
gene id: 30608:GDF7
uniprot id: A0A8B7I0V2
names: Similarity
messages: Belongs to the TGF-beta family.

30608:FAM91A1
gene id: 30608:FAM91A1
uniprot id: A0A8B7EW71
uniprot id: A0A8C5XNV1
names: Similarity
messages: Belongs to the FAM91 family.

30608:SELENOT
gene id: 30608:SELENOT
uniprot id: A0A8B7HL81
names: Similarity
messages: Belongs to the SelWTH family. Selenoprotein T subfamily.

30608:WNT8B
gene id: 30608:WNT8B
uniprot id: A0A8B7GMU1
uniprot id: A0A8B7WLS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

30608:WDR91
gene id: 30608:WDR91
uniprot id: A0A8B7EXN9
uniprot id: A0A8B7EXP4
uniprot id: A0A8B7EZJ0
uniprot id: A0A8B7EZR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR91 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

30608:LOC105856717
gene id: 30608:LOC105856717
uniprot id: A0A8B7EHU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane
messages: Membrane

30608:LOC105884163
gene id: 30608:LOC105884163
uniprot id: A0A8B7HYL0
names: Subcellular Location Annotation
messages: Membrane

30608:IL10
gene id: 30608:IL10
uniprot id: A0A8B7G1S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

30608:CCNY
gene id: 30608:CCNY
uniprot id: A0A8B7WY63
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

30608:CASP10
gene id: 30608:CASP10
uniprot id: A0A8B7EIK6
names: Similarity
messages: Belongs to the peptidase C14A family.

30608:LOC105883328
gene id: 30608:LOC105883328
uniprot id: A0A8B7HUT7
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105859447
gene id: 30608:LOC105859447
uniprot id: A0A8C6EHX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly.
messages: Membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

30608:PSAPL1
gene id: 30608:PSAPL1
uniprot id: A0A8B7HMQ6
names: Subcellular Location Annotation
messages: Secreted

30608:DIP2B
gene id: 30608:DIP2B
uniprot id: A0A8B7G5Q4
uniprot id: A0A8B7G5R8
uniprot id: A0A8B7G6I7
names: Similarity
messages: Belongs to the DIP2 family.

30608:TMEM208
gene id: 30608:TMEM208
uniprot id: A0A8B7ES68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM208 family.
messages: Endoplasmic reticulum membrane
messages: May function as a negative regulator of endoplasmic reticulum-stress induced autophagy.
messages: Membrane

30608:ABCC1
gene id: 30608:ABCC1
uniprot id: A0A8B7WPI4
uniprot id: A0A8B7WPI8
uniprot id: A0A8B7WPM6
uniprot id: A0A8B7WQW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

30608:GALR1
gene id: 30608:GALR1
uniprot id: A0A8C5VJW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

30608:LOC105862471
gene id: 30608:LOC105862471
uniprot id: A0A8B7F8E0
names: Similarity
messages: Belongs to the peptidase C14A family.

30608:LOC105856237
gene id: 30608:LOC105856237
uniprot id: A0A8B7EG39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

30608:LOC105879724
gene id: 30608:LOC105879724
uniprot id: A0A8B7WRR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGME1 family.
messages: Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair.
messages: Mitochondrion

30608:LOC105859457
gene id: 30608:LOC105859457
uniprot id: A0A8B7EW46
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:TNFSF11
gene id: 30608:TNFSF11
uniprot id: A0A8B7G2Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

30608:B2M
gene id: 30608:B2M
uniprot id: A0A8C5UUJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-2-microglobulin family.
messages: Secreted

30608:SPI1
gene id: 30608:SPI1
uniprot id: A0A8B7I2C5
uniprot id: A0A8B7I4D6
uniprot id: A0A8B7I4E6
uniprot id: A0A8B7I5C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

30608:CSNK1G2
gene id: 30608:CSNK1G2
uniprot id: A0A8B7F013
uniprot id: A0A8B7F015
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

30608:IL17F
gene id: 30608:IL17F
uniprot id: A0A8B7G2M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

30608:FOXB2
gene id: 30608:FOXB2
uniprot id: A0A8C5XN97
names: Subcellular Location Annotation
messages: Nucleus

30608:TCEA2
gene id: 30608:TCEA2
uniprot id: A0A8B7GXX7
uniprot id: A0A8B7GXY0
uniprot id: A0A8B7GXZ4
uniprot id: A0A8B7GY28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

30608:ACTL6B
gene id: 30608:ACTL6B
uniprot id: A0A8B7FZE2
uniprot id: A0A8C5XD10
uniprot id: A0A8C5XQW8
names: Similarity
messages: Belongs to the actin family.

30608:DYDC1
gene id: 30608:DYDC1
uniprot id: A0A8B7G6T7
uniprot id: A0A8B7G7C4
uniprot id: A0A8B7G7S9
names: Similarity
messages: Belongs to the dpy-30 family.

30608:EME1
gene id: 30608:EME1
uniprot id: A0A8B7I671
uniprot id: A0A8B7WNK0
names: Similarity
messages: Belongs to the EME1/MMS4 family.

30608:PRKCG
gene id: 30608:PRKCG
uniprot id: A0A8B7GST0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domain.
messages: Cytoplasm
messages: Membrane

30608:LOC105868762
gene id: 30608:LOC105868762
uniprot id: A0A8B7G1L9
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

30608:PAPOLG
gene id: 30608:PAPOLG
uniprot id: A0A8B7GCE4
uniprot id: A0A8B7GCE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Nucleus

30608:LOC105867974
gene id: 30608:LOC105867974
uniprot id: A0A8B7WXG2
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:LOC105859368
gene id: 30608:LOC105859368
uniprot id: A0A8B7EVP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105883333
gene id: 30608:LOC105883333
uniprot id: A0A8B7HUT5
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105862247
gene id: 30608:LOC105862247
uniprot id: A0A8B7F7X0
names: Subcellular Location Annotation
messages: Membrane

30608:AGBL3
gene id: 30608:AGBL3
uniprot id: A0A8B7EXP0
uniprot id: A0A8B7XBX4
uniprot id: A0A8B7XBX8
uniprot id: A0A8B7XCW8
uniprot id: A0A8B7XCX4
uniprot id: A0A8B7XDN0
uniprot id: A0A8B7XDN4
uniprot id: A0A8B7XE53
uniprot id: A0A8B7XE57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

30608:C20H16orf70
gene id: 30608:C20H16orf70
uniprot id: A0A8B7WS34
uniprot id: A0A8C5XW92
names: Similarity
messages: Belongs to the PHAF1 family.

30608:VPS26B
gene id: 30608:VPS26B
uniprot id: A0A8C5XKB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS26 family.
messages: Endosome

30608:ZDHHC17
gene id: 30608:ZDHHC17
uniprot id: A0A8B7FCA1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

30608:MOB3B
gene id: 30608:MOB3B
uniprot id: A0A8B7GBV6
names: Similarity
messages: Belongs to the MOB1/phocein family.

30608:ALKBH2
gene id: 30608:ALKBH2
uniprot id: A0A8B7FSH4
uniprot id: A0A8B7FSJ1
names: Similarity
messages: Belongs to the alkB family.

30608:PRR15
gene id: 30608:PRR15
uniprot id: A0A8B7EAN3
names: Similarity
messages: Belongs to the PRR15 family.

30608:AGAP3
gene id: 30608:AGAP3
uniprot id: A0A8C5W0T5
names: Similarity
messages: Belongs to the centaurin gamma-like family.

30608:NPTXR
gene id: 30608:NPTXR
uniprot id: A0A8B7X815
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:AKAP12
gene id: 30608:AKAP12
uniprot id: A0A8B7EN93
uniprot id: A0A8B7EN97
uniprot id: A0A8B7ENF4
uniprot id: A0A8B7EQG1
names: Subcellular Location Annotation
messages: Membrane

30608:RPS5
gene id: 30608:RPS5
uniprot id: A0A8C5VJ30
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

30608:VNN1
gene id: 30608:VNN1
uniprot id: A0A8B7ED78
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

30608:POLR2D
gene id: 30608:POLR2D
uniprot id: A0A8B7EM47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

30608:TRAPPC6A
gene id: 30608:TRAPPC6A
uniprot id: A0A8B7G433
uniprot id: A0A8B7G5F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

30608:MAP3K8
gene id: 30608:MAP3K8
uniprot id: A0A8B7I1L3
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

30608:RETNLB
gene id: 30608:RETNLB
uniprot id: A0A8C5YFL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistin/FIZZ family.
messages: Secreted

30608:LOC105860128
gene id: 30608:LOC105860128
uniprot id: A0A8B7EXJ3
uniprot id: A0A8B7WLC3
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105863936
gene id: 30608:LOC105863936
uniprot id: A0A8B7FF77
uniprot id: A0A8B7FFD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

30608:HABP4
gene id: 30608:HABP4
uniprot id: A0A8C5Y180
uniprot id: A0A8C5Y896
names: Similarity
messages: Belongs to the SERBP1-HABP4 family.

30608:LOC105862654
gene id: 30608:LOC105862654
uniprot id: A0A8C5YHT0
names: Similarity
messages: Belongs to the PRR23 family.

30608:PSD3
gene id: 30608:PSD3
uniprot id: A0A8B7HRI8
uniprot id: A0A8B7HRJ5
uniprot id: A0A8B7HRK0
uniprot id: A0A8B7HRK1
uniprot id: A0A8B7HTH9
uniprot id: A0A8C5UR97
names: Subcellular Location Annotation
messages: Membrane
messages: ruffle membrane

30608:TDO2
gene id: 30608:TDO2
uniprot id: A0A8C5V3E1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:SLC16A1
gene id: 30608:SLC16A1
uniprot id: A0A8B7HAY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

30608:PRKCB
gene id: 30608:PRKCB
uniprot id: A0A8B7HF00
uniprot id: A0A8B7HFH0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domain.
messages: Cytoplasm
messages: Membrane
messages: Nucleus

30608:INSIG1
gene id: 30608:INSIG1
uniprot id: A0A8B7XBP5
uniprot id: A0A8C5XX73
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

30608:ENPEP
gene id: 30608:ENPEP
uniprot id: A0A8B7GFV9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

30608:LOC105874977
gene id: 30608:LOC105874977
uniprot id: A0A8B7GTX6
names: Similarity
messages: Belongs to the histone H2B family.

30608:CPSF7
gene id: 30608:CPSF7
uniprot id: A0A8B7HAK1
uniprot id: A0A8B7HAK3
uniprot id: A0A8B7HAK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

30608:LOC109731370
gene id: 30608:LOC109731370
uniprot id: A0A8B7XFS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

30608:DPP3
gene id: 30608:DPP3
uniprot id: A0A8B7FUT7
uniprot id: A0A8B7FV02
uniprot id: A0A8B7FVQ5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M49 family.
messages: Binds 1 zinc ion per subunit.

30608:SGK2
gene id: 30608:SGK2
uniprot id: A0A8B7HH38
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:POPDC2
gene id: 30608:POPDC2
uniprot id: A0A8B7HG10
uniprot id: A0A8B7HIP5
names: Similarity
messages: Belongs to the popeye family.

30608:FITM2
gene id: 30608:FITM2
uniprot id: A0A8B7HGS2
uniprot id: A0A8C5Y4Y6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:C18H20orf27
gene id: 30608:C18H20orf27
uniprot id: A0A8B7FPF4
uniprot id: A0A8C5UN96
names: Similarity
messages: Belongs to the ADISSP family.

30608:TMEM132D
gene id: 30608:TMEM132D
uniprot id: A0A8B7WU53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

30608:TMPRSS2
gene id: 30608:TMPRSS2
uniprot id: A0A8B7FAZ6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105883507
gene id: 30608:LOC105883507
uniprot id: A0A8B7HXQ5
names: Similarity
messages: Belongs to the globin family.

30608:SPOP
gene id: 30608:SPOP
uniprot id: A0A8C5W435
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tdpoz family.
messages: Nucleus speckle

30608:MOK
gene id: 30608:MOK
uniprot id: A0A8B7F226
uniprot id: A0A8C6EKE3
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:KCNK15
gene id: 30608:KCNK15
uniprot id: A0A8B7HGQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

30608:CLCNKA
gene id: 30608:CLCNKA
uniprot id: A0A8B7WPB2
uniprot id: A0A8B7WPF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

30608:SMIM18
gene id: 30608:SMIM18
uniprot id: A0A8B7HP89
uniprot id: A0A8C6EKW0
names: Subcellular Location Annotation
messages: Membrane

30608:RNASET2
gene id: 30608:RNASET2
uniprot id: A0A8B7H6Z4
uniprot id: A0A8C5V679
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Lysosome lumen

30608:LIFR
gene id: 30608:LIFR
uniprot id: A0A8B7EET1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

30608:LOC105884432
gene id: 30608:LOC105884432
uniprot id: A0A8B7X8Y8
uniprot id: A0A8C5YBC1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

30608:ADI1
gene id: 30608:ADI1
uniprot id: A0A8B7G895
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. Also down-regulates cell migration mediated by MMP14.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer. Interacts with MMP14.
messages: Nucleus

30608:LOC105884132
gene id: 30608:LOC105884132
uniprot id: A0A8B7HYI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:APOO
gene id: 30608:APOO
uniprot id: A0A8B7WYY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

30608:LOC109730722
gene id: 30608:LOC109730722
uniprot id: A0A8B7X5K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:EIF4A2
gene id: 30608:EIF4A2
uniprot id: A0A8B7I2X9
uniprot id: A0A8C6ELJ0
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

30608:HSP90B1
gene id: 30608:HSP90B1
uniprot id: A0A8B7X7G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 90 family.
messages: Melanosome

30608:TTYH2
gene id: 30608:TTYH2
uniprot id: A0A8C5VW99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

30608:PROK2
gene id: 30608:PROK2
uniprot id: A0A8B7WZ68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

30608:ZBTB8OS
gene id: 30608:ZBTB8OS
uniprot id: A0A8B7GDU9
uniprot id: A0A8B7GED6
uniprot id: A0A8B7GEL3
uniprot id: A0A8B7GER7
names: Similarity
names: Subunit
messages: Belongs to the archease family.
messages: Component of the tRNA-splicing ligase complex.

30608:GPT2
gene id: 30608:GPT2
uniprot id: A0A8B7GZX8
uniprot id: A0A8C5V321
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

30608:ENPP2
gene id: 30608:ENPP2
uniprot id: A0A8B7FKT7
uniprot id: A0A8B7FKW1
uniprot id: A0A8B7FKY0
uniprot id: A0A8B7FM43
uniprot id: A0A8C5VUM3
uniprot id: A0A8C5XF34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Secreted

30608:FGD5
gene id: 30608:FGD5
uniprot id: A0A8B7WV10
names: Subcellular Location Annotation
messages: cytoskeleton

30608:CLNS1A
gene id: 30608:CLNS1A
uniprot id: A0A8B7EYR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pICln (TC 1.A.47) family.
messages: Nucleus

30608:ZHX1
gene id: 30608:ZHX1
uniprot id: A0A8B7XC53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

30608:PDSS1
gene id: 30608:PDSS1
uniprot id: A0A8B7H868
uniprot id: A0A8B7H884
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

30608:LOC105870536
gene id: 30608:LOC105870536
uniprot id: A0A8B7G8Z8
names: Subcellular Location Annotation
messages: Membrane

30608:UTS2B
gene id: 30608:UTS2B
uniprot id: A0A8B7EYV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

30608:CXCL9
gene id: 30608:CXCL9
uniprot id: A0A8B7EWL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

30608:HMX1
gene id: 30608:HMX1
uniprot id: A0A8C5YDL3
names: Subcellular Location Annotation
messages: Nucleus

30608:TSPO
gene id: 30608:TSPO
uniprot id: A0A8B7X8A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

30608:GSN
gene id: 30608:GSN
uniprot id: A0A8B7GUW4
uniprot id: A0A8B7GWI5
uniprot id: A0A8B7GWI9
uniprot id: A0A8C5VB20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the villin/gelsolin family.
messages: Binds to actin and to fibronectin. Identified in a complex composed of ACTA1, COBL, GSN and TMSB4X. Interacts with the inactive form of EIF2AK2/PKR.
messages: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.
messages: cytoskeleton

30608:RGS12
gene id: 30608:RGS12
uniprot id: A0A8B7EE99
uniprot id: A0A8B7EEA4
uniprot id: A0A8B7EEA8
uniprot id: A0A8B7EGV8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: dendrite

30608:TAGLN3
gene id: 30608:TAGLN3
uniprot id: A0A8B7HXJ0
names: Similarity
messages: Belongs to the calponin family.

30608:IRF1
gene id: 30608:IRF1
uniprot id: A0A8B7G5Q9
uniprot id: A0A8B7G6H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Nucleus

30608:BUD31
gene id: 30608:BUD31
uniprot id: A0A8B7FZG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

30608:NMD3
gene id: 30608:NMD3
uniprot id: A0A8B7HNH9
uniprot id: A0A8C5YGF3
uniprot id: A0A8C5YGF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

30608:LOC105869236
gene id: 30608:LOC105869236
uniprot id: A0A8C5V1F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

30608:LOC105857799
gene id: 30608:LOC105857799
uniprot id: A0A8B7EM93
uniprot id: A0A8B7ENF0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:CD4
gene id: 30608:CD4
uniprot id: A0A8B7G279
uniprot id: A0A8B7G333
uniprot id: A0A8B7X7X3
names: Subcellular Location Annotation
messages: Cell membrane

30608:FUT9
gene id: 30608:FUT9
uniprot id: A0A8B7GPL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Membrane

30608:RASGRP4
gene id: 30608:RASGRP4
uniprot id: A0A8B7H408
uniprot id: A0A8B7WU08
uniprot id: A0A8B7WU58
uniprot id: A0A8B7WVE9
names: Similarity
messages: Belongs to the RASGRP family.

30608:CHD1
gene id: 30608:CHD1
uniprot id: A0A8B7GZD5
uniprot id: A0A8B7H1B0
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105866793
gene id: 30608:LOC105866793
uniprot id: A0A8B7FS45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP53 family.
messages: nucleolus
messages: nucleoplasm

30608:LOC105865490
gene id: 30608:LOC105865490
uniprot id: A0A8B7FLL1
names: Similarity
messages: Belongs to the histone H3 family.

30608:CAMK2N2
gene id: 30608:CAMK2N2
uniprot id: A0A8C5YH10
names: Similarity
messages: Belongs to the CAMK2N family.

30608:AUH
gene id: 30608:AUH
uniprot id: A0A8B7H023
uniprot id: A0A8C5XSB3
uniprot id: A0A8C5XYY3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

30608:CLDN10
gene id: 30608:CLDN10
uniprot id: A0A8B7GQ46
uniprot id: A0A8B7GQA5
uniprot id: A0A8B7GRE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

30608:LOC109730724
gene id: 30608:LOC109730724
uniprot id: A0A8B7X5M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NFS1
gene id: 30608:NFS1
uniprot id: A0A8B7FNN6
uniprot id: A0A8C5V9D8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

30608:PGLYRP4
gene id: 30608:PGLYRP4
uniprot id: A0A8B7I704
uniprot id: A0A8B7I901
uniprot id: A0A8B7IAA1
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

30608:GSK3B
gene id: 30608:GSK3B
uniprot id: A0A8B7HG11
uniprot id: A0A8B7HG39
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

30608:EXOSC9
gene id: 30608:EXOSC9
uniprot id: A0A8B7HPF1
uniprot id: A0A8C5UX05
names: Subcellular Location Annotation
messages: Cytoplasm

30608:PIF1
gene id: 30608:PIF1
uniprot id: A0A8B7FXR3
uniprot id: A0A8B7FYN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Possesses an intrinsic strand annealing activity.
messages: Mitochondrion
messages: Monomer. Interacts with telomerase.
messages: Nucleus

30608:LOC105856694
gene id: 30608:LOC105856694
uniprot id: A0A8B7WXM6
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

30608:ETV5
gene id: 30608:ETV5
uniprot id: A0A8B7I5Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

30608:LOC105861253
gene id: 30608:LOC105861253
uniprot id: A0A8B7F2H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:COQ4
gene id: 30608:COQ4
uniprot id: A0A8B7GVN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane

30608:LOC105874136
gene id: 30608:LOC105874136
uniprot id: A0A8B7GQ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:ATF7
gene id: 30608:ATF7
uniprot id: A0A8B7GA84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Homodimer; binds DNA as homodimer. Heterodimer; heterodimerizes with other members of ATF family and with JUN family members.
messages: Nucleus
messages: Stress-responsive chromatin regulator that plays a role in various biological processes including innate immunological memory, adipocyte differentiation or telomerase regulation. In absence of stress, contributes to the formation of heterochromatin and heterochromatin-like structure by recruiting histone H3K9 tri- and di-methyltransferases thus silencing the transcription of target genes such as STAT1 in adipocytes, or genes involved in innate immunity in macrophages and adipocytes. Stress induces ATF7 phosphorylation that disrupts interactions with histone methyltransferase and enhances the association with coactivators containing histone acetyltransferase and/or histone demethylase, leading to disruption of the heterochromatin-like structure and subsequently transcriptional activation. In response to TNF-alpha, which is induced by various stresses, phosphorylated ATF7 and telomerase are released from telomeres leading to telomere shortening.

30608:TPI1
gene id: 30608:TPI1
uniprot id: A0A8B7G317
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

30608:CDH10
gene id: 30608:CDH10
uniprot id: A0A8B7GDV1
uniprot id: A0A8B7XCU7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

30608:DTX4
gene id: 30608:DTX4
uniprot id: A0A8B7FBV7
uniprot id: A0A8C5Y7S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

30608:SLC29A3
gene id: 30608:SLC29A3
uniprot id: A0A8B7G7J9
uniprot id: A0A8C5XK74
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

30608:EPHA7
gene id: 30608:EPHA7
uniprot id: A0A8B7FDN3
uniprot id: A0A8B7FDP1
uniprot id: A0A8B7FDP5
uniprot id: A0A8B7FDQ2
uniprot id: A0A8B7FDV8
uniprot id: A0A8B7FEJ6
names: Subcellular Location Annotation
messages: Membrane

30608:ENDOU
gene id: 30608:ENDOU
uniprot id: A0A8B7FK54
uniprot id: A0A8B7FKJ9
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

30608:LRP8
gene id: 30608:LRP8
uniprot id: A0A8B7H5P1
uniprot id: A0A8B7H5P4
uniprot id: A0A8B7H5P6
uniprot id: A0A8B7H5P9
uniprot id: A0A8B7H5Q1
uniprot id: A0A8B7H5R2
uniprot id: A0A8B7H5R7
uniprot id: A0A8B7H5S2
uniprot id: A0A8B7H816
uniprot id: A0A8B7H822
uniprot id: A0A8C5V8W2
uniprot id: A0A8C5XI64
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:LOC109730249
gene id: 30608:LOC109730249
uniprot id: A0A8B7WYY4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:LOC105864629
gene id: 30608:LOC105864629
uniprot id: A0A8B7X1Y7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

30608:CNIH4
gene id: 30608:CNIH4
uniprot id: A0A8B7FEP6
uniprot id: A0A8B7FFQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

30608:TRAF2
gene id: 30608:TRAF2
uniprot id: A0A8B7HQ64
uniprot id: A0A8B7HS01
uniprot id: A0A8B7HSL0
uniprot id: A0A8B7HSL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

30608:IL17RD
gene id: 30608:IL17RD
uniprot id: A0A8B7GEF3
uniprot id: A0A8B7GEF6
uniprot id: A0A8B7GEX9
uniprot id: A0A8B7GF71
uniprot id: A0A8B7GFB8
names: Subcellular Location Annotation
messages: Membrane

30608:CLN5
gene id: 30608:CLN5
uniprot id: A0A8B7EDP4
uniprot id: A0A8B7EEA2
names: Similarity
messages: Belongs to the CLN5 family.

30608:UCN3
gene id: 30608:UCN3
uniprot id: A0A8B7EP23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

30608:LOC105869878
gene id: 30608:LOC105869878
uniprot id: A0A8B7G5E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Cytoplasm

30608:TMEM263
gene id: 30608:TMEM263
uniprot id: A0A8B7X8G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

30608:LOC105879762
gene id: 30608:LOC105879762
uniprot id: A0A8B7HHV1
names: Similarity
messages: Belongs to the cystatin family.

30608:PHC1
gene id: 30608:PHC1
uniprot id: A0A8B7H8T5
uniprot id: A0A8B7H8T7
uniprot id: A0A8B7H8U7
uniprot id: A0A8B7HBH1
names: Subcellular Location Annotation
messages: Nucleus

30608:B3GALNT2
gene id: 30608:B3GALNT2
uniprot id: A0A8B7EHM2
uniprot id: A0A8B7EJ65
uniprot id: A0A8B7WQH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:EYS
gene id: 30608:EYS
uniprot id: A0A8B7X5B5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105871481
gene id: 30608:LOC105871481
uniprot id: A0A8B7GCF6
names: Similarity
messages: Belongs to the intermediate filament family.

30608:OIP5
gene id: 30608:OIP5
uniprot id: A0A8C5YBF5
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

30608:LOC105864449
gene id: 30608:LOC105864449
uniprot id: A0A8B7FH77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:POLR3A
gene id: 30608:POLR3A
uniprot id: A0A8B7G784
uniprot id: A0A8C5XC92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

30608:LOC105855634
gene id: 30608:LOC105855634
uniprot id: A0A8B7ECQ6
names: Similarity
messages: Belongs to the SPATA31 family.

30608:NSMCE2
gene id: 30608:NSMCE2
uniprot id: A0A8B7HSB3
uniprot id: A0A8B7HSB7
uniprot id: A0A8B7HSB9
uniprot id: A0A8B7HSC4
uniprot id: A0A8B7HUA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

30608:UTS2R
gene id: 30608:UTS2R
uniprot id: A0A8B7H857
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

30608:AMDHD1
gene id: 30608:AMDHD1
uniprot id: A0A8C5V3P5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.

30608:LOC105877669
gene id: 30608:LOC105877669
uniprot id: A0A8B7H8K4
names: Subcellular Location Annotation
messages: Membrane

30608:IGF2BP3
gene id: 30608:IGF2BP3
uniprot id: A0A8B7XBM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: P-body
messages: Stress granule

30608:CALR3
gene id: 30608:CALR3
uniprot id: A0A8C5XLB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen

30608:USP48
gene id: 30608:USP48
uniprot id: A0A8B7GM69
uniprot id: A0A8B7GMH7
uniprot id: A0A8B7GMI2
uniprot id: A0A8B7GMR0
uniprot id: A0A8B7WN28
uniprot id: A0A8C5YDM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Nucleus

30608:LOC105869132
gene id: 30608:LOC105869132
uniprot id: A0A8B7G3T1
uniprot id: A0A8B7WUB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

30608:MON1A
gene id: 30608:MON1A
uniprot id: A0A8B7WKZ2
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

30608:FOXP3
gene id: 30608:FOXP3
uniprot id: A0A8B7EGV6
uniprot id: A0A8B7EHB3
uniprot id: A0A8B7EIW2
names: Subcellular Location Annotation
messages: Nucleus

30608:UBE2S
gene id: 30608:UBE2S
uniprot id: A0A8B7FBY4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:BPGM
gene id: 30608:BPGM
uniprot id: A0A8B7EXS4
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

30608:ALLC
gene id: 30608:ALLC
uniprot id: A0A8B7G8Y8
names: Function
names: Similarity
messages: Belongs to the allantoicase family.
messages: The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals.

30608:LOC105859903
gene id: 30608:LOC105859903
uniprot id: A0A8B7EWB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

30608:TNS2
gene id: 30608:TNS2
uniprot id: A0A8B7G8I3
uniprot id: A0A8B7G8R5
uniprot id: A0A8B7G9Q2
uniprot id: A0A8C5V159
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

30608:LOC105878375
gene id: 30608:LOC105878375
uniprot id: A0A8B7H970
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

30608:ARID3B
gene id: 30608:ARID3B
uniprot id: A0A8B7E9R6
uniprot id: A0A8B7E9V5
uniprot id: A0A8B7E9Z4
uniprot id: A0A8B7EAG0
uniprot id: A0A8B7ECJ5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Heterodimer with ARID3A. Interacts with unphosphorylated RB1.
messages: Homodimer.
messages: Nucleus
messages: Transcription factor.

30608:TSHZ1
gene id: 30608:TSHZ1
uniprot id: A0A8B7G647
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

30608:SMG7
gene id: 30608:SMG7
uniprot id: A0A8B7EAP9
uniprot id: A0A8B7EAQ5
uniprot id: A0A8B7EAU3
uniprot id: A0A8B7EAX1
uniprot id: A0A8B7EB01
uniprot id: A0A8B7EB37
uniprot id: A0A8B7EBB6
uniprot id: A0A8B7EBC9
uniprot id: A0A8B7EBD3
uniprot id: A0A8B7EBD8
uniprot id: A0A8B7EDH3
uniprot id: A0A8C5W0J9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays a role in nonsense-mediated mRNA decay.

30608:CKS1B
gene id: 30608:CKS1B
uniprot id: A0A8B7GK97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

30608:LOC105885296
gene id: 30608:LOC105885296
uniprot id: A0A8B7I448
names: Similarity
messages: Belongs to the peptidase M16 family.

30608:FAM171B
gene id: 30608:FAM171B
uniprot id: A0A8B7HDD8
uniprot id: A0A8C5Y0T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

30608:RPL23A
gene id: 30608:RPL23A
uniprot id: A0A8B7EPQ2
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

30608:CD81
gene id: 30608:CD81
uniprot id: A0A8B7FVB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

30608:LOC105884808
gene id: 30608:LOC105884808
uniprot id: A0A8B7GYU3
names: Subcellular Location Annotation
messages: Nucleus

30608:GPKOW
gene id: 30608:GPKOW
uniprot id: A0A8B7EGE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOS2 family.
messages: Nucleus
messages: RNA-binding protein involved in pre-mRNA splicing.

30608:GTF2H1
gene id: 30608:GTF2H1
uniprot id: A0A8B7HG65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

30608:TACC2
gene id: 30608:TACC2
uniprot id: A0A8B7HHJ5
uniprot id: A0A8B7HHK3
uniprot id: A0A8B7HHK7
uniprot id: A0A8B7HHK8
uniprot id: A0A8B7HHL6
uniprot id: A0A8B7HHM0
uniprot id: A0A8B7HHM1
uniprot id: A0A8B7HHM3
uniprot id: A0A8B7HHN1
uniprot id: A0A8B7HHN7
uniprot id: A0A8B7HHP2
uniprot id: A0A8B7HIE2
uniprot id: A0A8B7HIE9
uniprot id: A0A8B7HIF7
uniprot id: A0A8B7HIG4
uniprot id: A0A8B7HIH1
uniprot id: A0A8B7HIH7
uniprot id: A0A8B7HK73
uniprot id: A0A8B7HK79
uniprot id: A0A8B7HK84
uniprot id: A0A8B7WM07
uniprot id: A0A8B7WM40
uniprot id: A0A8B7WN44
uniprot id: A0A8C5VHC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: centrosome

30608:FAM133A
gene id: 30608:FAM133A
uniprot id: A0A8B7FSZ7
names: Similarity
messages: Belongs to the FAM133 family.

30608:LOC109730837
gene id: 30608:LOC109730837
uniprot id: A0A8B7X795
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

30608:TRIM67
gene id: 30608:TRIM67
uniprot id: A0A8B7EHF3
names: Subcellular Location Annotation
messages: cytoskeleton

30608:LOC105864100
gene id: 30608:LOC105864100
uniprot id: A0A8B7WV32
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:DCT
gene id: 30608:DCT
uniprot id: A0A8C5XUR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

30608:C5H11orf54
gene id: 30608:C5H11orf54
uniprot id: A0A8B7EK73
uniprot id: A0A8B7ELF8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
messages: Monomer.
messages: Nucleus

30608:FASLG
gene id: 30608:FASLG
uniprot id: A0A8C5VSJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Cell membrane
messages: Cytoplasmic form induces gene transcription inhibition.
messages: Cytoplasmic vesicle lumen
messages: Lysosome lumen
messages: Nucleus
messages: Secreted

30608:ATP6V0C
gene id: 30608:ATP6V0C
uniprot id: A0A8B7EX49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane
messages: clathrin-coated vesicle membrane
messages: synaptic vesicle membrane

30608:LOC105885163
gene id: 30608:LOC105885163
uniprot id: A0A8B7I5F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Odorant receptor.

30608:HSF2
gene id: 30608:HSF2
uniprot id: A0A8B7H8N1
uniprot id: A0A8B7H8N8
uniprot id: A0A8C5V702
uniprot id: A0A8C5VU18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

30608:GPR135
gene id: 30608:GPR135
uniprot id: A0A8B7HV83
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:MKX
gene id: 30608:MKX
uniprot id: A0A8B7GQB6
uniprot id: A0A8C5VEE7
names: Subcellular Location Annotation
messages: Nucleus

30608:GNG7
gene id: 30608:GNG7
uniprot id: A0A8B7WWA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

30608:LOC105869963
gene id: 30608:LOC105869963
uniprot id: A0A8B7G5T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with UQCC6.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

30608:USO1
gene id: 30608:USO1
uniprot id: A0A8C5YBU3
uniprot id: A0A8C6EI98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VDP/USO1/EDE1 family.
messages: Membrane

30608:DDX50
gene id: 30608:DDX50
uniprot id: A0A8B7G734
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.

30608:TCF25
gene id: 30608:TCF25
uniprot id: A0A8B7EGK7
uniprot id: A0A8C5VBI1
names: Similarity
messages: Belongs to the TCF25 family.

30608:PCLAF
gene id: 30608:PCLAF
uniprot id: A0A8B7FXE3
uniprot id: A0A8C5V1U7
names: Subcellular Location Annotation
messages: Nucleus
messages: perinuclear region

30608:TIMM23
gene id: 30608:TIMM23
uniprot id: A0A8B7EXG3
uniprot id: A0A8B7EZH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

30608:PPARA
gene id: 30608:PPARA
uniprot id: A0A8B7FTW1
uniprot id: A0A8B7FTY2
uniprot id: A0A8B7FUW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
messages: Nucleus

30608:FABP7
gene id: 30608:FABP7
uniprot id: A0A8B7H8M9
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

30608:P2RX3
gene id: 30608:P2RX3
uniprot id: A0A8B7FB75
uniprot id: A0A8B7FBV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

30608:PAQR7
gene id: 30608:PAQR7
uniprot id: A0A8B7FCK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

30608:DGUOK
gene id: 30608:DGUOK
uniprot id: A0A8B7I3E8
uniprot id: A0A8B7X3W9
uniprot id: A0A8C5VTY7
names: Similarity
messages: Belongs to the DCK/DGK family.

30608:SUSD5
gene id: 30608:SUSD5
uniprot id: A0A8C5YFS8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105862335
gene id: 30608:LOC105862335
uniprot id: A0A8B7WUS5
names: Similarity
messages: Belongs to the TEX28 family.

30608:EVX1
gene id: 30608:EVX1
uniprot id: A0A8B7GYV5
names: Subcellular Location Annotation
messages: Nucleus

30608:RPL12
gene id: 30608:RPL12
uniprot id: A0A8B7XD24
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

30608:KIF20A
gene id: 30608:KIF20A
uniprot id: A0A8B7F9I9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:PTN
gene id: 30608:PTN
uniprot id: A0A8B7EXR4
uniprot id: A0A8B7EXR6
uniprot id: A0A8B7EZU2
names: Similarity
messages: Belongs to the pleiotrophin family.

30608:GHR
gene id: 30608:GHR
uniprot id: A0A8B7H974
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Cell membrane
messages: The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.

30608:PARG
gene id: 30608:PARG
uniprot id: A0A8B7EXE7
uniprot id: A0A8B7EZA5
uniprot id: A0A8B7EZG4
names: Similarity
messages: Belongs to the poly(ADP-ribose) glycohydrolase family.

30608:NMNAT1
gene id: 30608:NMNAT1
uniprot id: A0A8B7I7C3
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

30608:LOC105883465
gene id: 30608:LOC105883465
uniprot id: A0A8B7HVD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PSMD11
gene id: 30608:PSMD11
uniprot id: A0A8B7WPK0
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

30608:TRPC4
gene id: 30608:TRPC4
uniprot id: A0A8B7F722
uniprot id: A0A8C5VHL5
names: Subcellular Location Annotation
messages: Membrane

30608:SERPINE2
gene id: 30608:SERPINE2
uniprot id: A0A8B7G341
uniprot id: A0A8B7G343
uniprot id: A0A8B7G3Y8
names: Similarity
messages: Belongs to the serpin family.

30608:LOC105868400
gene id: 30608:LOC105868400
uniprot id: A0A8B7FZQ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:METTL1
gene id: 30608:METTL1
uniprot id: A0A8B7H7S8
uniprot id: A0A8C5YC57
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with WDR4.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Phosphorylation at Ser-28 inactivates its catalytic activity but does not affect the interaction with WDR4.

30608:OPRPN
gene id: 30608:OPRPN
uniprot id: A0A8B7HVV4
names: Subcellular Location Annotation
messages: Secreted

30608:MAB21L3
gene id: 30608:MAB21L3
uniprot id: A0A8B7G515
names: Similarity
messages: Belongs to the mab-21 family.

30608:ARPC5
gene id: 30608:ARPC5
uniprot id: A0A8B7EB47
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

30608:SMARCD2
gene id: 30608:SMARCD2
uniprot id: A0A8B7F4V0
uniprot id: A0A8C5W4L5
names: Similarity
messages: Belongs to the SMARCD family.

30608:FAM198A
gene id: 30608:FAM198A
uniprot id: A0A8B7GRL3
uniprot id: A0A8B7WUN4
uniprot id: A0A8B7WUR9
uniprot id: A0A8B7WV23
uniprot id: A0A8B7WW44
names: Similarity
messages: Belongs to the GASK family.

30608:EMC1
gene id: 30608:EMC1
uniprot id: A0A8B7HY46
uniprot id: A0A8B7HY57
uniprot id: A0A8B7I071
uniprot id: A0A8B7I0U6
uniprot id: A0A8C5UTA0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC1 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:S1PR3
gene id: 30608:S1PR3
uniprot id: A0A8B7GZR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MMD2
gene id: 30608:MMD2
uniprot id: A0A8B7FZ31
uniprot id: A0A8C5W4M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

30608:FAM135A
gene id: 30608:FAM135A
uniprot id: A0A8B7HWJ0
uniprot id: A0A8B7HWL1
uniprot id: A0A8B7HWM0
uniprot id: A0A8B7HWN2
uniprot id: A0A8B7HWP2
uniprot id: A0A8B7HWQ6
uniprot id: A0A8B7HYS3
uniprot id: A0A8B7HZ50
names: Similarity
messages: Belongs to the FAM135 family.

30608:HDAC8
gene id: 30608:HDAC8
uniprot id: A0A8B7HPR5
uniprot id: A0A8B7HPS5
uniprot id: A0A8B7HRH3
uniprot id: A0A8B7HS64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Belongs to the histone deacetylase family. HD type 1 subfamily.
messages: Nucleus

30608:LOC105859566
gene id: 30608:LOC105859566
uniprot id: A0A8B7EUH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105885302
gene id: 30608:LOC105885302
uniprot id: A0A8B7I784
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105876122
gene id: 30608:LOC105876122
uniprot id: A0A8B7GZN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP9 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm

30608:TMA16
gene id: 30608:TMA16
uniprot id: A0A8B7ECT2
names: Function
names: Similarity
names: Subunit
messages: Associates with pre-60S ribosomal particles.
messages: Belongs to the TMA16 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit in the nucleus.

30608:CCR7
gene id: 30608:CCR7
uniprot id: A0A8B7GFG1
uniprot id: A0A8C5VGH1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:NAA40
gene id: 30608:NAA40
uniprot id: A0A8B7H9I2
uniprot id: A0A8B7HC97
uniprot id: A0A8C5VR16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

30608:SLC35A1
gene id: 30608:SLC35A1
uniprot id: A0A8B7FDL8
uniprot id: A0A8B7FDN6
uniprot id: A0A8C5VA02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

30608:LOC105865645
gene id: 30608:LOC105865645
uniprot id: A0A8B7X6C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Odorant receptor.

30608:ALK
gene id: 30608:ALK
uniprot id: A0A8B7HZS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane

30608:LOC105868417
gene id: 30608:LOC105868417
uniprot id: A0A8B7FZ02
uniprot id: A0A8B7FZW0
uniprot id: A0A8B7G042
names: Similarity
messages: Belongs to the MHC class I family.

30608:ZBED4
gene id: 30608:ZBED4
uniprot id: A0A8B7I2U0
names: Subcellular Location Annotation
messages: Nucleus

30608:TMEM55A
gene id: 30608:TMEM55A
uniprot id: A0A8B7G2A3
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: phagosome membrane

30608:LOC105865727
gene id: 30608:LOC105865727
uniprot id: A0A8B7FMJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Odorant receptor.

30608:LOC105885304
gene id: 30608:LOC105885304
uniprot id: A0A8B7I482
names: Subcellular Location Annotation
messages: Membrane

30608:CHRNB4
gene id: 30608:CHRNB4
uniprot id: A0A8B7ELX9
uniprot id: A0A8B7X1W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:SHROOM4
gene id: 30608:SHROOM4
uniprot id: A0A8B7FGQ8
uniprot id: A0A8B7FGS8
uniprot id: A0A8B7FGX7
uniprot id: A0A8B7FGY2
uniprot id: A0A8B7FHZ0
uniprot id: A0A8C5VY36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

30608:PTCD3
gene id: 30608:PTCD3
uniprot id: A0A8B7H307
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS39 family.
messages: Mitochondrion

30608:AU129 gp02
gene id: 30608:AU129_gp02
uniprot id: A0A0U2S4M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion membrane

30608:LOC105860481
gene id: 30608:LOC105860481
uniprot id: A0A8B7WZ99
names: Similarity
messages: Belongs to the FRAS1 family.

30608:SP4
gene id: 30608:SP4
uniprot id: A0A8B7HH05
uniprot id: A0A8B7HJN2
uniprot id: A0A8C5W772
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105867136
gene id: 30608:LOC105867136
uniprot id: A0A8B7FTG1
names: Similarity
messages: Belongs to the PPase family.

30608:GPR33
gene id: 30608:GPR33
uniprot id: A0A8B7GZ15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

30608:SSR1
gene id: 30608:SSR1
uniprot id: A0A8B7FKA7
uniprot id: A0A8B7FKF1
uniprot id: A0A8C5YA88
uniprot id: A0A8C5YAN3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-alpha family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma. Interacts with palmitoylated calnexin (CALX), the interaction is required for efficient folding of glycosylated proteins.
messages: Membrane
messages: Shows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged.
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.

30608:LOC105885157
gene id: 30608:LOC105885157
uniprot id: A0A8B7I3F5
names: Subcellular Location Annotation
messages: Membrane

30608:PDHB
gene id: 30608:PDHB
uniprot id: A0A8B7I4B6
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

30608:ITPA
gene id: 30608:ITPA
uniprot id: A0A8B7FND9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Cytoplasm
messages: Homodimer.
messages: Pyrophosphatase that hydrolyzes the non-canonical purine (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

30608:SVIL
gene id: 30608:SVIL
uniprot id: A0A8B7I1I9
uniprot id: A0A8B7I1J1
uniprot id: A0A8B7I1J5
uniprot id: A0A8B7I1J7
uniprot id: A0A8B7I1J8
uniprot id: A0A8B7I3L7
uniprot id: A0A8B7I3M2
uniprot id: A0A8B7I4D3
uniprot id: A0A8B7I4E0
uniprot id: A0A8B7I4E5
uniprot id: A0A8B7WWG6
uniprot id: A0A8B7WY71
names: Similarity
messages: Belongs to the villin/gelsolin family.

30608:TMEM242
gene id: 30608:TMEM242
uniprot id: A0A8B7G0R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM242 family.
messages: Membrane

30608:TMSB10
gene id: 30608:TMSB10
uniprot id: A0A8B7HFB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

30608:INTU
gene id: 30608:INTU
uniprot id: A0A8B7WKK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inturned family.
messages: Cell surface
messages: cilium basal body

30608:GNA14
gene id: 30608:GNA14
uniprot id: A0A8B7G038
uniprot id: A0A8B7G1B7
uniprot id: A0A8C5UVT5
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

30608:CBFB
gene id: 30608:CBFB
uniprot id: A0A8B7ESG1
uniprot id: A0A8B7ESG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF-beta family.
messages: Nucleus

30608:ALDH4A1
gene id: 30608:ALDH4A1
uniprot id: A0A8C5WA81
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

30608:LOC105871038
gene id: 30608:LOC105871038
uniprot id: A0A8C5W1T3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Inflammasome

30608:USP5
gene id: 30608:USP5
uniprot id: A0A8B7G1J5
uniprot id: A0A8B7G1K0
uniprot id: A0A8B7G2Y9
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

30608:EPHB3
gene id: 30608:EPHB3
uniprot id: A0A8C5YFD1
names: Subcellular Location Annotation
messages: Membrane

30608:MRPL35
gene id: 30608:MRPL35
uniprot id: A0A8C5YAG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL35 family.
messages: Mitochondrion

30608:SLC16A6
gene id: 30608:SLC16A6
uniprot id: A0A8B7F598
uniprot id: A0A8B7F5A7
uniprot id: A0A8C5Y2E0
names: Subcellular Location Annotation
messages: Membrane

30608:PARVA
gene id: 30608:PARVA
uniprot id: A0A8C5URY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: Cell membrane
messages: Membrane

30608:KIF6
gene id: 30608:KIF6
uniprot id: A0A8B7HAM6
uniprot id: A0A8C6EJ77
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:NT5DC4
gene id: 30608:NT5DC4
uniprot id: A0A8B7EST4
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

30608:UBE2G1
gene id: 30608:UBE2G1
uniprot id: A0A8B7HCT5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:LOC105865361
gene id: 30608:LOC105865361
uniprot id: A0A8B7FKY5
uniprot id: A0A8C5XV92
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

30608:DDX31
gene id: 30608:DDX31
uniprot id: A0A8B7EW93
uniprot id: A0A8C5XRG2
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

30608:ATP6AP1
gene id: 30608:ATP6AP1
uniprot id: A0A8B7FX84
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

30608:DDX53
gene id: 30608:DDX53
uniprot id: A0A8B7HQE9
names: Similarity
messages: Belongs to the DEAD box helicase family.

30608:C5AR2
gene id: 30608:C5AR2
uniprot id: A0A8B7G4B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

30608:SLC2A4
gene id: 30608:SLC2A4
uniprot id: A0A8B7H707
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Endomembrane system
messages: Membrane
messages: perinuclear region

30608:CDK5R1
gene id: 30608:CDK5R1
uniprot id: A0A8C5XXR5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit and a regulatory subunit.
messages: Membrane

30608:VAMP8
gene id: 30608:VAMP8
uniprot id: A0A8B7H2Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

30608:LOC105858302
gene id: 30608:LOC105858302
uniprot id: A0A8C5Y4W5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:SMARCAD1
gene id: 30608:SMARCAD1
uniprot id: A0A8B7WXK0
names: Subcellular Location Annotation
messages: Chromosome

30608:MUC4
gene id: 30608:MUC4
uniprot id: A0A8B7HI72
uniprot id: A0A8B7X476
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:TOP1MT
gene id: 30608:TOP1MT
uniprot id: A0A8B7FIL7
uniprot id: A0A8B7FJX7
uniprot id: A0A8B7XA26
uniprot id: A0A8B7XA28
uniprot id: A0A8B7XAT9
uniprot id: A0A8B7XBS4
uniprot id: A0A8B7XC75
uniprot id: A0A8C5V2S7
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

30608:GCLM
gene id: 30608:GCLM
uniprot id: A0A8B7I657
names: Similarity
names: Subunit
messages: Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.
messages: Heterodimer of a catalytic heavy chain and a regulatory light chain.

30608:FEZ1
gene id: 30608:FEZ1
uniprot id: A0A8C5XHP2
names: Similarity
messages: Belongs to the zygin family.

30608:RNFT1
gene id: 30608:RNFT1
uniprot id: A0A8B7GVV1
uniprot id: A0A8B7GVZ0
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105860485
gene id: 30608:LOC105860485
uniprot id: A0A8C5W973
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

30608:LOC105867538
gene id: 30608:LOC105867538
uniprot id: A0A8B7FV90
uniprot id: A0A8B7FW78
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:STAT4
gene id: 30608:STAT4
uniprot id: A0A8B7H771
uniprot id: A0A8B7H774
uniprot id: A0A8B7H776
uniprot id: A0A8B7H794
uniprot id: A0A8B7H9Q1
uniprot id: A0A8C5VMG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

30608:MASP1
gene id: 30608:MASP1
uniprot id: A0A8B7I2W8
uniprot id: A0A8B7I2X8
uniprot id: A0A8B7I4Y5
uniprot id: A0A8B7I5W4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:MBOAT1
gene id: 30608:MBOAT1
uniprot id: A0A8B7FKD4
uniprot id: A0A8B7FLP4
names: Subcellular Location Annotation
messages: Membrane

30608:CACNB4
gene id: 30608:CACNB4
uniprot id: A0A8B7HEI3
uniprot id: A0A8B7HEK8
uniprot id: A0A8B7HEX2
uniprot id: A0A8C5VLE3
names: Similarity
messages: Belongs to the calcium channel beta subunit family.

30608:LYAR
gene id: 30608:LYAR
uniprot id: A0A8B7EKA5
names: Subcellular Location Annotation
messages: Cytoplasm

30608:AUP1
gene id: 30608:AUP1
uniprot id: A0A8C5Y256
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AUP1 family.
messages: Membrane

30608:LOC105864697
gene id: 30608:LOC105864697
uniprot id: A0A8B7FI26
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

30608:SERPINE1
gene id: 30608:SERPINE1
uniprot id: A0A8C5Y0P6
names: Similarity
messages: Belongs to the serpin family.

30608:KCNA4
gene id: 30608:KCNA4
uniprot id: A0A8B7FW75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.4/KCNA4 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: axon

30608:FGF14
gene id: 30608:FGF14
uniprot id: A0A8B7XEP7
uniprot id: A0A8C5UY92
uniprot id: A0A8C5VT53
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

30608:APPL2
gene id: 30608:APPL2
uniprot id: A0A8B7GXA7
uniprot id: A0A8B7GXB1
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: Nucleus
messages: phagosome
messages: ruffle

30608:SRP19
gene id: 30608:SRP19
uniprot id: A0A8C6EHY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP19 family.
messages: Cytoplasm

30608:CPEB4
gene id: 30608:CPEB4
uniprot id: A0A8B7GE61
uniprot id: A0A8B7GEN9
uniprot id: A0A8B7GEX4
uniprot id: A0A8B7GF27
names: Similarity
messages: Belongs to the RRM CPEB family.

30608:APOA5
gene id: 30608:APOA5
uniprot id: A0A8B7GZJ3
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

30608:ISCA2
gene id: 30608:ISCA2
uniprot id: A0A8C5XWM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

30608:EEF1A2
gene id: 30608:EEF1A2
uniprot id: A0A8B7GXR2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

30608:CXCL16
gene id: 30608:CXCL16
uniprot id: A0A8B7HDH0
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105864589
gene id: 30608:LOC105864589
uniprot id: A0A8B7FHX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SF3B4
gene id: 30608:SF3B4
uniprot id: A0A8B7FLP3
uniprot id: A0A8C5YCH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B4 family.
messages: Nucleus

30608:LOC105883386
gene id: 30608:LOC105883386
uniprot id: A0A8B7HX48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SLC30A10
gene id: 30608:SLC30A10
uniprot id: A0A8B7I7C0
uniprot id: A0A8B7I7I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

30608:LOC105879993
gene id: 30608:LOC105879993
uniprot id: A0A8C5VIG6
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:LOC105858691
gene id: 30608:LOC105858691
uniprot id: A0A8C5UVD5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:FAM92A
gene id: 30608:FAM92A
uniprot id: A0A8B7GXJ4
uniprot id: A0A8B7GXL3
uniprot id: A0A8B7GXP5
uniprot id: A0A8B7GZF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CIBAR family.
messages: centriole
messages: cilium basal body

30608:RRP36
gene id: 30608:RRP36
uniprot id: A0A8B7GYE5
uniprot id: A0A8C5YE40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with 90S and pre-40S pre-ribosomal particles.
messages: Belongs to the RRP36 family.
messages: Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
messages: nucleolus

30608:PIAS3
gene id: 30608:PIAS3
uniprot id: A0A8B7G585
uniprot id: A0A8B7G591
uniprot id: A0A8B7G610
uniprot id: A0A8C5W4Z8
uniprot id: A0A8C5W7A0
names: Similarity
messages: Belongs to the PIAS family.

30608:FZD2
gene id: 30608:FZD2
uniprot id: A0A8B7HXN9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:LOC105858310
gene id: 30608:LOC105858310
uniprot id: A0A8B7EP93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus

30608:RTN3
gene id: 30608:RTN3
uniprot id: A0A8B7H9E4
uniprot id: A0A8B7H9E5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:EIF3F
gene id: 30608:EIF3F
uniprot id: A0A8B7HNT6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit F family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.

30608:SAMD4A
gene id: 30608:SAMD4A
uniprot id: A0A8B7X1N0
uniprot id: A0A8C5XYC9
uniprot id: A0A8C5Y540
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

30608:LOC109730981
gene id: 30608:LOC109730981
uniprot id: A0A8B7X967
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

30608:LOC105861302
gene id: 30608:LOC105861302
uniprot id: A0A8B7F2M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TAF9B
gene id: 30608:TAF9B
uniprot id: A0A8B7FPS2
uniprot id: A0A8B7WYV3
uniprot id: A0A8B7WYV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

30608:WDR12
gene id: 30608:WDR12
uniprot id: A0A8B7EIE9
uniprot id: A0A8C5Y294
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

30608:OPTN
gene id: 30608:OPTN
uniprot id: A0A8B7GEN1
uniprot id: A0A8B7WXZ2
uniprot id: A0A8C5XZ72
names: Function
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Golgi apparatus
messages: May act by regulating membrane trafficking and cellular morphogenesis.
messages: Recycling endosome
messages: autophagosome
messages: perinuclear region
messages: trans-Golgi network

30608:RARG
gene id: 30608:RARG
uniprot id: A0A8C5V8T3
uniprot id: A0A8C5VGE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

30608:KIF3B
gene id: 30608:KIF3B
uniprot id: A0A8B7FNC5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:LOC105862591
gene id: 30608:LOC105862591
uniprot id: A0A8B7F8W5
uniprot id: A0A8B7F8Y1
uniprot id: A0A8B7F914
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:LOC105864539
gene id: 30608:LOC105864539
uniprot id: A0A8B7FHJ2
names: Subcellular Location Annotation
messages: Membrane

30608:SPNS1
gene id: 30608:SPNS1
uniprot id: A0A8C5Y2P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

30608:PDX1
gene id: 30608:PDX1
uniprot id: A0A8B7ETC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

30608:ISG15
gene id: 30608:ISG15
uniprot id: A0A8B7H666
names: Subcellular Location Annotation
messages: cytosol

30608:SLC25A16
gene id: 30608:SLC25A16
uniprot id: A0A8C5VQT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:LOC105877016
gene id: 30608:LOC105877016
uniprot id: A0A8B7H5A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lambda interferon family.
messages: Secreted

30608:PPP1R3C
gene id: 30608:PPP1R3C
uniprot id: A0A8B7GF67
uniprot id: A0A8B7GF70
names: Domain
names: Function
names: Subunit
messages: Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown.
messages: Interacts with PPP1CC catalytic subunit of PP1 and associates with glycogen. Forms complexes with glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity.
messages: The N-terminal region is required for binding to PP1, the central region is required for binding to glycogen and the C-terminal region is required for binding to glycogen phosphorylase glycogen synthase and phosphorylase kinase.

30608:LOC105884119
gene id: 30608:LOC105884119
uniprot id: A0A8B7HYH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:FAM49B
gene id: 30608:FAM49B
uniprot id: A0A8B7HSD1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CYRI family.
messages: Interacts with RAC1 (GTP-bound form preferentially).
messages: Membrane

30608:HOXC13
gene id: 30608:HOXC13
uniprot id: A0A8C6EI33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

30608:USP7
gene id: 30608:USP7
uniprot id: A0A8B7HRY9
uniprot id: A0A8B7HRZ3
names: Similarity
messages: Belongs to the peptidase C19 family.

30608:LOC105885960
gene id: 30608:LOC105885960
uniprot id: A0A8B7I714
uniprot id: A0A8B7IAB1
names: Similarity
messages: Belongs to the LCE family.

30608:VKORC1
gene id: 30608:VKORC1
uniprot id: A0A8C5VG12
uniprot id: A0A8C5Y408
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:MID1
gene id: 30608:MID1
uniprot id: A0A8B7HR09
uniprot id: A0A8B7HTC8
names: Subcellular Location Annotation
messages: cytoskeleton

30608:LOC105876665
gene id: 30608:LOC105876665
uniprot id: A0A8B7WV20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

30608:FGF20
gene id: 30608:FGF20
uniprot id: A0A8B7HTR1
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

30608:DHX9
gene id: 30608:DHX9
uniprot id: A0A8C5UUP8
uniprot id: A0A8C6EI32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Nucleus

30608:RPE65
gene id: 30608:RPE65
uniprot id: A0A8B7GIL4
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

30608:ZNF174
gene id: 30608:ZNF174
uniprot id: A0A8B7EX78
uniprot id: A0A8C5VND9
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105857576
gene id: 30608:LOC105857576
uniprot id: A0A8B7EL01
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

30608:TNFSF4
gene id: 30608:TNFSF4
uniprot id: A0A8B7GD42
uniprot id: A0A8B7GD43
uniprot id: A0A8B7GDT1
uniprot id: A0A8B7GE16
uniprot id: A0A8C5XVK6
names: Similarity
messages: Belongs to the tumor necrosis factor family.

30608:NR1I3
gene id: 30608:NR1I3
uniprot id: A0A8B7GLX3
uniprot id: A0A8C5XCK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

30608:LOC105880386
gene id: 30608:LOC105880386
uniprot id: A0A8B7WRA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGME1 family.
messages: Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair.
messages: Mitochondrion

30608:CDC14A
gene id: 30608:CDC14A
uniprot id: A0A8B7F818
uniprot id: A0A8B7F820
uniprot id: A0A8B7F823
uniprot id: A0A8B7F827
uniprot id: A0A8B7F829
uniprot id: A0A8B7F867
uniprot id: A0A8B7F8C4
uniprot id: A0A8B7F8D0
uniprot id: A0A8B7F8D7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

30608:LOC105883565
gene id: 30608:LOC105883565
uniprot id: A0A8B7HXX9
uniprot id: A0A8B7HY45
names: Subcellular Location Annotation
messages: nucleolus

30608:UBN1
gene id: 30608:UBN1
uniprot id: A0A8B7EV64
uniprot id: A0A8B7EX59
names: Similarity
messages: Belongs to the ubinuclein family.

30608:FABP12
gene id: 30608:FABP12
uniprot id: A0A8B7ELC7
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

30608:LOC109731232
gene id: 30608:LOC109731232
uniprot id: A0A8B7XCU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105861250
gene id: 30608:LOC105861250
uniprot id: A0A8B7F2H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CACNA2D1
gene id: 30608:CACNA2D1
uniprot id: A0A8B7XDV9
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

30608:MRPL42
gene id: 30608:MRPL42
uniprot id: A0A8C5VEV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL42 family.
messages: Mitochondrion

30608:LOC105859388
gene id: 30608:LOC105859388
uniprot id: A0A8B7ETU1
uniprot id: A0A8B7ETU3
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

30608:ARPC3
gene id: 30608:ARPC3
uniprot id: A0A8B7HL68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

30608:PSMD1
gene id: 30608:PSMD1
uniprot id: A0A8B7F9V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S1 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

30608:EPB41
gene id: 30608:EPB41
uniprot id: A0A8B7FCJ7
uniprot id: A0A8B7FCK2
uniprot id: A0A8B7FCK7
uniprot id: A0A8B7FCL0
uniprot id: A0A8B7FCL2
uniprot id: A0A8B7FCL4
uniprot id: A0A8B7FCL5
uniprot id: A0A8B7FCL7
uniprot id: A0A8B7FCL9
uniprot id: A0A8B7FCM3
uniprot id: A0A8B7FCM5
uniprot id: A0A8B7FCM9
uniprot id: A0A8B7FCN1
uniprot id: A0A8B7FCN5
uniprot id: A0A8B7FCN6
uniprot id: A0A8B7FCP1
uniprot id: A0A8B7FCR9
uniprot id: A0A8B7FCS3
uniprot id: A0A8B7FCS9
uniprot id: A0A8B7FCU1
uniprot id: A0A8B7FDC8
uniprot id: A0A8B7FDD5
uniprot id: A0A8B7FDE1
uniprot id: A0A8B7FDF1
uniprot id: A0A8B7FDF6
names: Subcellular Location Annotation
messages: Nucleus
messages: cell cortex
messages: cytoskeleton

30608:FOXI1
gene id: 30608:FOXI1
uniprot id: A0A8B7GIL6
names: Subcellular Location Annotation
messages: Nucleus

30608:RNASE12
gene id: 30608:RNASE12
uniprot id: A0A8B7FIF2
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

30608:CLCN1
gene id: 30608:CLCN1
uniprot id: A0A8B7GKN9
uniprot id: A0A8B7GKP0
uniprot id: A0A8B7GL08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

30608:GRPR
gene id: 30608:GRPR
uniprot id: A0A8B7HQR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:KCNMB2
gene id: 30608:KCNMB2
uniprot id: A0A8B7EE71
uniprot id: A0A8B7EE76
uniprot id: A0A8B7EG72
uniprot id: A0A8B7X339
uniprot id: A0A8C5YGD0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KCNMB (TC 8.A.14.1) family.
messages: Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB per KCNMA1 tetramer.
messages: Membrane
messages: N-glycosylated.
messages: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

30608:PKD1
gene id: 30608:PKD1
uniprot id: A0A8B7EUH9
uniprot id: A0A8B7EUI7
uniprot id: A0A8B7EWG9
uniprot id: A0A8B7EWH5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:DPY19L3
gene id: 30608:DPY19L3
uniprot id: A0A8B7H333
uniprot id: A0A8B7H591
uniprot id: A0A8C5YI56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

30608:NAA38
gene id: 30608:NAA38
uniprot id: A0A8B7H4U9
names: Function
names: Similarity
names: Subunit
messages: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues.
messages: Belongs to the snRNP Sm proteins family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.

30608:GTPBP4
gene id: 30608:GTPBP4
uniprot id: A0A8C5WBB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

30608:LOC105861294
gene id: 30608:LOC105861294
uniprot id: A0A8B7F445
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105867085
gene id: 30608:LOC105867085
uniprot id: A0A8B7X0I3
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

30608:LOC105875312
gene id: 30608:LOC105875312
uniprot id: A0A8B7XCJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MOB3A
gene id: 30608:MOB3A
uniprot id: A0A8B7F045
names: Similarity
messages: Belongs to the MOB1/phocein family.

30608:LOC105884144
gene id: 30608:LOC105884144
uniprot id: A0A8B7I182
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:STK32B
gene id: 30608:STK32B
uniprot id: A0A8B7EKB1
uniprot id: A0A8B7EKM6
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:TTC9B
gene id: 30608:TTC9B
uniprot id: A0A8C6EK66
names: Similarity
messages: Belongs to the TTC9 family.

30608:LOC105884611
gene id: 30608:LOC105884611
uniprot id: A0A8B7I0P2
uniprot id: A0A8B7I0P3
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

30608:FAM131A
gene id: 30608:FAM131A
uniprot id: A0A8B7ED72
uniprot id: A0A8B7EDU6
uniprot id: A0A8C6EM37
names: Similarity
messages: Belongs to the FAM131 family.

30608:IFITM5
gene id: 30608:IFITM5
uniprot id: A0A8C5UTX0
names: Similarity
messages: Belongs to the CD225/Dispanin family.

30608:MRRF
gene id: 30608:MRRF
uniprot id: A0A8B7GUV6
uniprot id: A0A8B7GV17
uniprot id: A0A8B7GWN3
names: Function
names: Similarity
messages: Belongs to the RRF family.
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

30608:RC3H2
gene id: 30608:RC3H2
uniprot id: A0A8B7GUY2
uniprot id: A0A8B7GV42
uniprot id: A0A8C5VTQ1
names: Subcellular Location Annotation
messages: P-body

30608:QRSL1
gene id: 30608:QRSL1
uniprot id: A0A8B7X4U3
uniprot id: A0A8B7X6Q6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

30608:PRPSAP2
gene id: 30608:PRPSAP2
uniprot id: A0A8B7F6M9
uniprot id: A0A8C5Y822
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

30608:TMEM198
gene id: 30608:TMEM198
uniprot id: A0A8B7ELB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

30608:LOC105884138
gene id: 30608:LOC105884138
uniprot id: A0A8B7I0L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105862357
gene id: 30608:LOC105862357
uniprot id: A0A8B7F7Z5
uniprot id: A0A8B7F826
uniprot id: A0A8B7WUG8
names: Subcellular Location Annotation
messages: Nucleus

30608:CCBE1
gene id: 30608:CCBE1
uniprot id: A0A8B7EZR0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:DGKQ
gene id: 30608:DGKQ
uniprot id: A0A8B7HMI7
uniprot id: A0A8B7HMI8
uniprot id: A0A8B7HMJ0
uniprot id: A0A8B7HP03
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

30608:TMEM30B
gene id: 30608:TMEM30B
uniprot id: A0A8B7HBJ9
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

30608:COPB1
gene id: 30608:COPB1
uniprot id: A0A8C5VWR5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Endoplasmic reticulum-Golgi intermediate compartment
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

30608:DRD1
gene id: 30608:DRD1
uniprot id: A0A8B7HJ57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
messages: Membrane
messages: dendritic spine

30608:LOC105883463
gene id: 30608:LOC105883463
uniprot id: A0A8B7HXJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105863122
gene id: 30608:LOC105863122
uniprot id: A0A8B7FB15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TRAPPC13
gene id: 30608:TRAPPC13
uniprot id: A0A8B7HP52
uniprot id: A0A8B7HQT3
uniprot id: A0A8B7XCP3
uniprot id: A0A8B7XEY4
names: Similarity
names: Subunit
messages: Belongs to the TRAPPC13 family.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.

30608:LOC105860414
gene id: 30608:LOC105860414
uniprot id: A0A8B7WWM7
names: Subcellular Location Annotation
messages: nucleolus

30608:LOC105860531
gene id: 30608:LOC105860531
uniprot id: A0A8B7EZA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane

30608:MEX3B
gene id: 30608:MEX3B
uniprot id: A0A8C6EI62
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:SLC41A1
gene id: 30608:SLC41A1
uniprot id: A0A8C5VMK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

30608:KEAP1
gene id: 30608:KEAP1
uniprot id: A0A8B7I7C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KEAP1 family.
messages: Cytoplasm
messages: Nucleus

30608:ATR
gene id: 30608:ATR
uniprot id: A0A8B7G6A4
uniprot id: A0A8B7G6A6
uniprot id: A0A8B7G6B1
uniprot id: A0A8B7G6F1
uniprot id: A0A8B7G714
uniprot id: A0A8B7G7I3
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.

30608:MTMR4
gene id: 30608:MTMR4
uniprot id: A0A8B7GCS6
uniprot id: A0A8B7GE11
uniprot id: A0A8B7GE76
uniprot id: A0A8C5W825
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm
messages: Membrane

30608:TERF2IP
gene id: 30608:TERF2IP
uniprot id: A0A8C5XXF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with terf2. Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with terf2 or other factors, and regulates gene expression.
messages: Belongs to the RAP1 family.
messages: Homodimer.
messages: Nucleus
messages: telomere

30608:CEPT1
gene id: 30608:CEPT1
uniprot id: A0A8B7FFF0
uniprot id: A0A8B7FFH4
uniprot id: A0A8B7FFN2
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

30608:LOC105869684
gene id: 30608:LOC105869684
uniprot id: A0A8B7WVZ5
uniprot id: A0A8B7WWN3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:TDRD9
gene id: 30608:TDRD9
uniprot id: A0A8B7F229
uniprot id: A0A8B7F231
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily.

30608:LOC105874980
gene id: 30608:LOC105874980
uniprot id: A0A8C5VC28
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

30608:LOC105883029
gene id: 30608:LOC105883029
uniprot id: A0A8B7HTI6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

30608:MAL
gene id: 30608:MAL
uniprot id: A0A8B7HW20
names: Subcellular Location Annotation
messages: Membrane

30608:ADAM15
gene id: 30608:ADAM15
uniprot id: A0A8B7GK45
uniprot id: A0A8B7GK47
uniprot id: A0A8B7GKF9
uniprot id: A0A8B7GKG4
uniprot id: A0A8B7GKR7
uniprot id: A0A8B7GKS2
uniprot id: A0A8B7GLA4
uniprot id: A0A8B7GLB0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105859899
gene id: 30608:LOC105859899
uniprot id: A0A8B7X5P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105866385
gene id: 30608:LOC105866385
uniprot id: A0A8B7FQS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ADGRL3
gene id: 30608:ADGRL3
uniprot id: A0A8B7GIU8
uniprot id: A0A8B7GIU9
uniprot id: A0A8B7GJ65
uniprot id: A0A8B7GJ77
uniprot id: A0A8B7GJ82
uniprot id: A0A8B7GJH1
uniprot id: A0A8B7GJH6
uniprot id: A0A8B7GJI1
uniprot id: A0A8B7GJX0
uniprot id: A0A8B7GJX6
uniprot id: A0A8B7GJY2
uniprot id: A0A8C5UQL9
uniprot id: A0A8C5VKF9
uniprot id: A0A8C5VPL8
uniprot id: A0A8C5W721
names: Subcellular Location Annotation
messages: Membrane

30608:CDH1
gene id: 30608:CDH1
uniprot id: A0A8B7ERW7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

30608:CTPS2
gene id: 30608:CTPS2
uniprot id: A0A8B7HQQ0
uniprot id: A0A8B7HQQ8
uniprot id: A0A8B7HSJ8
uniprot id: A0A8B7HT32
uniprot id: A0A8B7HT36
uniprot id: A0A8C5UXJ2
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

30608:BSCL2
gene id: 30608:BSCL2
uniprot id: A0A8B7HAC5
uniprot id: A0A8B7HAC6
uniprot id: A0A8B7HAC8
uniprot id: A0A8B7HAD1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:NOTCH1
gene id: 30608:NOTCH1
uniprot id: A0A8C5UZY1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

30608:LOC105883085
gene id: 30608:LOC105883085
uniprot id: A0A8B7HVY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

30608:DCST1
gene id: 30608:DCST1
uniprot id: A0A8B7GK60
uniprot id: A0A8B7GK65
uniprot id: A0A8B7GK67
uniprot id: A0A8B7GKI1
uniprot id: A0A8B7GKS7
uniprot id: A0A8B7GKT3
uniprot id: A0A8B7GLC2
uniprot id: A0A8C5WA32
names: Subcellular Location Annotation
messages: Membrane

30608:SNX25
gene id: 30608:SNX25
uniprot id: A0A8B7HR63
uniprot id: A0A8B7HR69
uniprot id: A0A8B7HR80
uniprot id: A0A8B7HT34
uniprot id: A0A8B7HTI9
names: Similarity
messages: Belongs to the sorting nexin family.

30608:SYNE4
gene id: 30608:SYNE4
uniprot id: A0A8B7H2Q0
names: Similarity
messages: Belongs to the nesprin family.

30608:CACNA1C
gene id: 30608:CACNA1C
uniprot id: A0A8B7X5G2
uniprot id: A0A8B7X5G3
uniprot id: A0A8B7X5G8
uniprot id: A0A8B7X5G9
uniprot id: A0A8B7X5H5
uniprot id: A0A8B7X5I0
uniprot id: A0A8B7X620
uniprot id: A0A8B7X628
uniprot id: A0A8B7X634
uniprot id: A0A8B7X773
uniprot id: A0A8B7X780
uniprot id: A0A8B7X787
uniprot id: A0A8B7X792
uniprot id: A0A8B7X7F1
uniprot id: A0A8B7X7G0
uniprot id: A0A8B7X7G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1C subfamily.
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic density membrane
messages: T-tubule
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.
messages: dendrite
messages: sarcolemma

30608:LOC105859847
gene id: 30608:LOC105859847
uniprot id: A0A8B7EY26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM15 family.
messages: Membrane

30608:LOC105858269
gene id: 30608:LOC105858269
uniprot id: A0A8B7XDC8
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.

30608:EIF3E
gene id: 30608:EIF3E
uniprot id: A0A8B7HWR3
uniprot id: A0A8C5XNF2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with COPS3, COPS6, COPS7 (COPS7A or COPS7B), EIF4G1, EPAS1, MCM7, NCBP1, PSMC6, TRIM27 and UPF2.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. Required for nonsense-mediated mRNA decay (NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: PML body
messages: Phosphorylated upon DNA damage, probably by ATM or ATR.

30608:LOC105869127
gene id: 30608:LOC105869127
uniprot id: A0A8B7G2D0
uniprot id: A0A8B7G3S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

30608:IFNAR1
gene id: 30608:IFNAR1
uniprot id: A0A8B7F4C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II cytokine receptor family.
messages: Cell membrane
messages: Endosome
messages: Heterodimer with IFNAR2.
messages: Late endosome
messages: Lysosome
messages: Membrane
messages: Together with IFNAR2, forms the heterodimeric receptor for type I interferons (including interferons alpha, beta, epsilon, omega and kappa). Type I interferon binding activates the JAK-STAT signaling cascade. Can also act independently of IFNAR2: form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway.

30608:LOC105863751
gene id: 30608:LOC105863751
uniprot id: A0A8B7FEE6
uniprot id: A0A8B7FEN4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:PSAP
gene id: 30608:PSAP
uniprot id: A0A8B7G6V0
uniprot id: A0A8B7G6V3
uniprot id: A0A8B7WLC9
names: Function
names: Subcellular Location Annotation
messages: Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.
messages: Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases.
messages: Secreted

30608:MAPK7
gene id: 30608:MAPK7
uniprot id: A0A8B7F6I5
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

30608:TAF12
gene id: 30608:TAF12
uniprot id: A0A8B7FCV1
uniprot id: A0A8B7FD08
uniprot id: A0A8B7FDM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

30608:RAB19
gene id: 30608:RAB19
uniprot id: A0A8B7GKS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane

30608:LONP1
gene id: 30608:LONP1
uniprot id: A0A8C5XUA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters.
messages: Belongs to the peptidase S16 family.
messages: Homohexamer. Organized in a ring with a central cavity. The ATP-binding and proteolytic domains (AP-domain) form a hexameric chamber, while the N-terminal domain is arranged as a trimer of dimers. DNA and RNA binding is stimulated by substrate and inhibited by ATP binding. Interacts with TWNK and mitochondrial DNA polymerase subunit POLG.
messages: Mitochondrion matrix

30608:SCG5
gene id: 30608:SCG5
uniprot id: A0A8B7GG93
uniprot id: A0A8B7GGA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.
messages: Belongs to the 7B2 family.
messages: Interacts with PCSK2/PC2 early in the secretory pathway. Dissociation occurs at later stages.
messages: Secreted

30608:SPHKAP
gene id: 30608:SPHKAP
uniprot id: A0A8B7FA07
uniprot id: A0A8B7FA12
uniprot id: A0A8B7FA76
uniprot id: A0A8B7FAM5
uniprot id: A0A8B7X7J1
uniprot id: A0A8C5VNI0
names: Similarity
messages: Belongs to the AKAP110 family.

30608:LOC105858747
gene id: 30608:LOC105858747
uniprot id: A0A8B7ER34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

30608:SLC5A10
gene id: 30608:SLC5A10
uniprot id: A0A8B7F6J8
uniprot id: A0A8B7F6K0
uniprot id: A0A8B7F6L0
uniprot id: A0A8B7F6N0
uniprot id: A0A8B7F6Q5
uniprot id: A0A8B7F6R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

30608:BCO1
gene id: 30608:BCO1
uniprot id: A0A8B7F2B2
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

30608:FAM234A
gene id: 30608:FAM234A
uniprot id: A0A8B7EFE9
names: Similarity
messages: Belongs to the FAM234 family.

30608:MMP8
gene id: 30608:MMP8
uniprot id: A0A8C5V1S2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

30608:LOC105884308
gene id: 30608:LOC105884308
uniprot id: A0A8B7HZ23
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

30608:RASGRP1
gene id: 30608:RASGRP1
uniprot id: A0A8B7GGD0
uniprot id: A0A8B7GGE1
uniprot id: A0A8B7GGT8
uniprot id: A0A8B7GH80
names: Similarity
messages: Belongs to the RASGRP family.

30608:LOC105854864
gene id: 30608:LOC105854864
uniprot id: A0A8B7ECI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

30608:GPC4
gene id: 30608:GPC4
uniprot id: A0A8B7GD86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

30608:LOC105883431
gene id: 30608:LOC105883431
uniprot id: A0A8B7HV35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MFSD11
gene id: 30608:MFSD11
uniprot id: A0A8B7HC17
uniprot id: A0A8B7HC20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

30608:LOC105878819
gene id: 30608:LOC105878819
uniprot id: A0A8B7HDX7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:LOC105861266
gene id: 30608:LOC105861266
uniprot id: A0A8B7F2J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TMEM88
gene id: 30608:TMEM88
uniprot id: A0A8C5VGG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM88 family.
messages: Membrane

30608:HSF1
gene id: 30608:HSF1
uniprot id: A0A8B7G166
uniprot id: A0A8B7X9X9
uniprot id: A0A8B7XAW9
uniprot id: A0A8C5V6D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

30608:UTP11
gene id: 30608:UTP11
uniprot id: A0A8C5ULW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

30608:LOC105861990
gene id: 30608:LOC105861990
uniprot id: A0A8B7WPP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

30608:TMPRSS5
gene id: 30608:TMPRSS5
uniprot id: A0A8B7FJJ8
uniprot id: A0A8B7FJK2
uniprot id: A0A8B7FJK5
uniprot id: A0A8B7FJN6
uniprot id: A0A8B7FJS6
uniprot id: A0A8B7FKZ7
uniprot id: A0A8B7FL02
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:DOCK2
gene id: 30608:DOCK2
uniprot id: A0A8B7WV95
names: Similarity
messages: Belongs to the DOCK family.

30608:SKA1
gene id: 30608:SKA1
uniprot id: A0A8B7GQ39
names: Similarity
messages: Belongs to the SKA1 family.

30608:CAPRIN1
gene id: 30608:CAPRIN1
uniprot id: A0A8B7X316
uniprot id: A0A8B7X3L1
uniprot id: A0A8B7X4T0
names: Similarity
messages: Belongs to the caprin family.

30608:GFOD1
gene id: 30608:GFOD1
uniprot id: A0A8C5UJQ5
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

30608:LOC105865739
gene id: 30608:LOC105865739
uniprot id: A0A8B7X8D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

30608:CDK2AP1
gene id: 30608:CDK2AP1
uniprot id: A0A8B7HM84
uniprot id: A0A8C5VJZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDK2AP family.
messages: Nucleus

30608:RGMA
gene id: 30608:RGMA
uniprot id: A0A8B7F7X7
uniprot id: A0A8C5VQW2
uniprot id: A0A8C5YD08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

30608:PARK7
gene id: 30608:PARK7
uniprot id: A0A8B7WQA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C56 family.
messages: Membrane raft

30608:HIF3A
gene id: 30608:HIF3A
uniprot id: A0A8B7G452
uniprot id: A0A8B7G456
uniprot id: A0A8B7G4Y4
uniprot id: A0A8C5VE15
names: Subcellular Location Annotation
messages: Nucleus
messages: Nucleus speckle

30608:CD200R1
gene id: 30608:CD200R1
uniprot id: A0A8C5YG83
names: Similarity
messages: Belongs to the CD200R family.

30608:ELOA
gene id: 30608:ELOA
uniprot id: A0A8B7WMI9
names: Subcellular Location Annotation
messages: Nucleus

30608:TINAG
gene id: 30608:TINAG
uniprot id: A0A8B7X6G6
uniprot id: A0A8C5VHW8
names: Similarity
messages: Belongs to the peptidase C1 family.

30608:LOC105881946
gene id: 30608:LOC105881946
uniprot id: A0A8B7HNT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:KCNA10
gene id: 30608:KCNA10
uniprot id: A0A8B7FF93
names: Subcellular Location Annotation
messages: Membrane

30608:BLK
gene id: 30608:BLK
uniprot id: A0A8B7FIS1
uniprot id: A0A8B7FK25
uniprot id: A0A8C5XTV3
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

30608:LANCL1
gene id: 30608:LANCL1
uniprot id: A0A8B7FF45
uniprot id: A0A8B7FG60
names: Similarity
messages: Belongs to the LanC-like protein family.

30608:HCFC1
gene id: 30608:HCFC1
uniprot id: A0A8B7FU17
uniprot id: A0A8B7FU60
uniprot id: A0A8B7FUU5
uniprot id: A0A8B7FV14
names: Subcellular Location Annotation
messages: Nucleus

30608:DPM3
gene id: 30608:DPM3
uniprot id: A0A8B7GKD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM3 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.

30608:GMPR2
gene id: 30608:GMPR2
uniprot id: A0A8B7FR46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

30608:GAS6
gene id: 30608:GAS6
uniprot id: A0A8B7GE74
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:CRTC1
gene id: 30608:CRTC1
uniprot id: A0A8B7WVY5
uniprot id: A0A8B7WW95
uniprot id: A0A8B7WXN4
uniprot id: A0A8C5Y982
uniprot id: A0A8C6EL29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Cytoplasm
messages: Nucleus

30608:TRAPPC1
gene id: 30608:TRAPPC1
uniprot id: A0A8B7H6M5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

30608:HOXC10
gene id: 30608:HOXC10
uniprot id: A0A8B7GAL2
uniprot id: A0A8B7X5K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

30608:LOC105881341
gene id: 30608:LOC105881341
uniprot id: A0A8B7XCR8
names: Caution
names: Similarity
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:SBNO1
gene id: 30608:SBNO1
uniprot id: A0A8B7HKP8
names: Similarity
messages: Belongs to the SBNO family.

30608:RPL34
gene id: 30608:RPL34
uniprot id: A0A8B7GGT4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

30608:MIOX
gene id: 30608:MIOX
uniprot id: A0A8B7I2N9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myo-inositol oxygenase family.
messages: Binds 2 iron ions per subunit.
messages: Cytoplasm

30608:AHCY
gene id: 30608:AHCY
uniprot id: A0A8B7FN19
uniprot id: A0A8B7FP63
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

30608:TMEM200C
gene id: 30608:TMEM200C
uniprot id: A0A8B7F3C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

30608:MYO10
gene id: 30608:MYO10
uniprot id: A0A8B7XDW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: cytoskeleton

30608:LOC105882659
gene id: 30608:LOC105882659
uniprot id: A0A8B7HS23
uniprot id: A0A8B7HUB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

30608:DNAJA2
gene id: 30608:DNAJA2
uniprot id: A0A8B7WSF6
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105871377
gene id: 30608:LOC105871377
uniprot id: A0A8B7GC14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MEP1A
gene id: 30608:MEP1A
uniprot id: A0A8B7X5B1
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:SMIM19
gene id: 30608:SMIM19
uniprot id: A0A8B7H8B6
uniprot id: A0A8B7H8D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM19 family.
messages: Membrane

30608:C2H1orf52
gene id: 30608:C2H1orf52
uniprot id: A0A8B7F5P5
uniprot id: A0A8B7F5Q1
uniprot id: A0A8B7WSM0
names: Similarity
messages: Belongs to the UPF0690 family.

30608:UPP2
gene id: 30608:UPP2
uniprot id: A0A8B7EZ69
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

30608:KCNN4
gene id: 30608:KCNN4
uniprot id: A0A8B7G3M6
uniprot id: A0A8C5XCM6
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105859897
gene id: 30608:LOC105859897
uniprot id: A0A8B7EYB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105861247
gene id: 30608:LOC105861247
uniprot id: A0A8B7F2H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CD40LG
gene id: 30608:CD40LG
uniprot id: A0A8B7FS40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effects, such as B-cell activation, NF-kappa-B signaling and anti-apoptotic signaling.
messages: Belongs to the tumor necrosis factor family.
messages: Cell surface
messages: Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
messages: Homotrimer.

30608:UFC1
gene id: 30608:UFC1
uniprot id: A0A8C5VDF3
names: Function
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
messages: E1-like enzyme which specifically catalyzes the second step in ufmylation. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.

30608:LOC105868334
gene id: 30608:LOC105868334
uniprot id: A0A8B7FYB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

30608:PMEPA1
gene id: 30608:PMEPA1
uniprot id: A0A8B7GRN7
uniprot id: A0A8B7GRP0
uniprot id: A0A8B7GRY1
uniprot id: A0A8B7GS02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

30608:SETD1B
gene id: 30608:SETD1B
uniprot id: A0A8B7HJW6
uniprot id: A0A8B7HL25
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus speckle

30608:FOPNL
gene id: 30608:FOPNL
uniprot id: A0A8B7I6E7
uniprot id: A0A8C5W374
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP43 family.
messages: centriole
messages: cilium basal body

30608:OTUB1
gene id: 30608:OTUB1
uniprot id: A0A8B7HCB3
names: Similarity
messages: Belongs to the peptidase C65 family.

30608:PDK3
gene id: 30608:PDK3
uniprot id: A0A8B7HQC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

30608:LOC105879237
gene id: 30608:LOC105879237
uniprot id: A0A8B7HD14
names: Similarity
messages: Belongs to the SPATA31 family.

30608:DDX5
gene id: 30608:DDX5
uniprot id: A0A8B7F525
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.

30608:CRP
gene id: 30608:CRP
uniprot id: A0A8B7FHC7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:LOC105859235
gene id: 30608:LOC105859235
uniprot id: A0A8B7EV41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CLASP2
gene id: 30608:CLASP2
uniprot id: A0A8B7GNG7
uniprot id: A0A8B7GNG8
uniprot id: A0A8B7GNG9
uniprot id: A0A8B7GNH2
uniprot id: A0A8B7GNI2
uniprot id: A0A8B7GNS5
uniprot id: A0A8B7GNT0
uniprot id: A0A8B7GP06
uniprot id: A0A8B7GP11
uniprot id: A0A8B7GPV4
uniprot id: A0A8B7WNT3
uniprot id: A0A8B7WNY5
uniprot id: A0A8B7WP31
uniprot id: A0A8B7WP56
uniprot id: A0A8B7WP80
uniprot id: A0A8B7WPF1
uniprot id: A0A8B7WPH1
uniprot id: A0A8B7WPR4
uniprot id: A0A8B7WPW6
uniprot id: A0A8B7WPZ3
uniprot id: A0A8B7WQ73
uniprot id: A0A8B7WQC0
uniprot id: A0A8B7WQI5
uniprot id: A0A8B7WQJ2
uniprot id: A0A8B7WQL5
uniprot id: A0A8B7WQN0
uniprot id: A0A8B7WQS2
names: Subcellular Location Annotation
messages: kinetochore

30608:LOC105880096
gene id: 30608:LOC105880096
uniprot id: A0A8B7HJC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

30608:POU1F1
gene id: 30608:POU1F1
uniprot id: A0A8C5UW30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

30608:LOC105857140
gene id: 30608:LOC105857140
uniprot id: A0A8B7EJK5
names: Similarity
messages: Belongs to the PHYHIP family.

30608:ADGRF4
gene id: 30608:ADGRF4
uniprot id: A0A8B7EXX7
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105860665
gene id: 30608:LOC105860665
uniprot id: A0A8B7EZT5
names: Similarity
messages: Belongs to the OSBP family.

30608:MFSD5
gene id: 30608:MFSD5
uniprot id: A0A8B7GA77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Cell membrane
messages: Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.
messages: Membrane

30608:DDX1
gene id: 30608:DDX1
uniprot id: A0A8B7H692
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX1 subfamily.
messages: Cytoplasmic granule
messages: RNA helicase.
messages: The helicase domain is involved in the stimulation of RELA transcriptional activity.

30608:SERPINI2
gene id: 30608:SERPINI2
uniprot id: A0A8B7FI34
uniprot id: A0A8C5YET6
names: Similarity
messages: Belongs to the serpin family.

30608:SPATA18
gene id: 30608:SPATA18
uniprot id: A0A8B7GMC0
uniprot id: A0A8B7GMW0
uniprot id: A0A8B7GNN1
uniprot id: A0A8B7WYN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIEAP family.
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion outer membrane

30608:PDK1
gene id: 30608:PDK1
uniprot id: A0A8C5UT82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

30608:TELO2
gene id: 30608:TELO2
uniprot id: A0A8B7WPF0
names: Similarity
messages: Belongs to the TEL2 family.

30608:CPSF2
gene id: 30608:CPSF2
uniprot id: A0A8B7H015
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

30608:LOC105862355
gene id: 30608:LOC105862355
uniprot id: A0A8B7F7Y2
names: Subcellular Location Annotation
messages: Membrane

30608:PYGL
gene id: 30608:PYGL
uniprot id: A0A8B7FVS9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

30608:LOC105875316
gene id: 30608:LOC105875316
uniprot id: A0A8B7GW13
names: Subcellular Location Annotation
messages: Membrane

30608:TUBGCP3
gene id: 30608:TUBGCP3
uniprot id: A0A8B7FG98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

30608:APEX1
gene id: 30608:APEX1
uniprot id: A0A8B7FID6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Cytoplasm
messages: Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
messages: Mitochondrion
messages: Nucleus
messages: Probably binds two magnesium or manganese ions per subunit.

30608:ADRA2B
gene id: 30608:ADRA2B
uniprot id: A0A8B7HW59
uniprot id: A0A8B7HY85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
messages: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2B sub-subfamily.
messages: Cell membrane
messages: Membrane

30608:ISL2
gene id: 30608:ISL2
uniprot id: A0A8C5XW61
names: Subcellular Location Annotation
messages: Nucleus

30608:BBS5
gene id: 30608:BBS5
uniprot id: A0A8B7HJ05
uniprot id: A0A8C5VZW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BBS5 family.
messages: Membrane
messages: Part of BBSome complex, that contains BBS1, BBS2, BBS4, BBS5, BBS7, BBS8/TTC8, BBS9 and BBIP10.
messages: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for BBSome complex ciliary localization but not for the proper complex assembly.
messages: centriolar satellite
messages: cilium membrane

30608:TP53INP2
gene id: 30608:TP53INP2
uniprot id: A0A8B7FMS0
uniprot id: A0A8B7FN15
uniprot id: A0A8B7FP41
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

30608:CAMK4
gene id: 30608:CAMK4
uniprot id: A0A8C5VEP7
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:RCE1
gene id: 30608:RCE1
uniprot id: A0A8B7FUQ3
uniprot id: A0A8B7FVR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:LOC105862298
gene id: 30608:LOC105862298
uniprot id: A0A8B7F7V6
uniprot id: A0A8B7F7Y8
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105863902
gene id: 30608:LOC105863902
uniprot id: A0A8B7FF15
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

30608:SCUBE1
gene id: 30608:SCUBE1
uniprot id: A0A8B7X6Z5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:LOC105875224
gene id: 30608:LOC105875224
uniprot id: A0A8B7GVE6
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

30608:ALDH16A1
gene id: 30608:ALDH16A1
uniprot id: A0A8C5VTN2
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Interacts with SPG21.

30608:FAM57B
gene id: 30608:FAM57B
uniprot id: A0A8B7GB10
uniprot id: A0A8B7GBH0
uniprot id: A0A8B7GC17
names: Subcellular Location Annotation
messages: Membrane

30608:SGIP1
gene id: 30608:SGIP1
uniprot id: A0A8B7GIC2
uniprot id: A0A8B7GID0
uniprot id: A0A8B7GID4
uniprot id: A0A8B7GID5
uniprot id: A0A8B7GID9
uniprot id: A0A8B7GIE4
uniprot id: A0A8B7GIF0
uniprot id: A0A8B7GIQ7
uniprot id: A0A8B7GIR2
uniprot id: A0A8B7GIR7
uniprot id: A0A8B7GIS2
uniprot id: A0A8B7GJ05
uniprot id: A0A8B7GJ10
uniprot id: A0A8B7GJ15
uniprot id: A0A8B7GJ20
uniprot id: A0A8B7GJD2
uniprot id: A0A8B7GJD9
uniprot id: A0A8B7GJE6
uniprot id: A0A8B7GJF1
uniprot id: A0A8B7X9V0
uniprot id: A0A8C6ECW4
names: Function
names: Subcellular Location Annotation
messages: May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a preference for membranes enriched in phosphatidylserine and phosphoinositides and is required for the endocytosis of the transferrin receptor. May also bind tubulin. May play a role in the regulation of energy homeostasis.
messages: clathrin-coated pit

30608:SMAD6
gene id: 30608:SMAD6
uniprot id: A0A8B7FYK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

30608:CPT2
gene id: 30608:CPT2
uniprot id: A0A8C5UIB3
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

30608:LOC105861311
gene id: 30608:LOC105861311
uniprot id: A0A8B7F452
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PPRC1
gene id: 30608:PPRC1
uniprot id: A0A8B7GPN2
uniprot id: A0A8B7GPP3
uniprot id: A0A8B7GPY8
uniprot id: A0A8B7GPZ3
names: Subcellular Location Annotation
messages: Nucleus

30608:PAGE4
gene id: 30608:PAGE4
uniprot id: A0A8B7EGG0
names: Similarity
messages: Belongs to the GAGE family.

30608:FGFR1
gene id: 30608:FGFR1
uniprot id: A0A8B7G7W5
uniprot id: A0A8B7G830
uniprot id: A0A8B7G8K6
uniprot id: A0A8B7G8Z9
uniprot id: A0A8B7G902
uniprot id: A0A8B7WRV5
uniprot id: A0A8B7WRW6
uniprot id: A0A8C5Y745
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Membrane
messages: Nucleus
messages: Vesicle
messages: cytosol

30608:LOC105862413
gene id: 30608:LOC105862413
uniprot id: A0A8B7F879
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:C1RL
gene id: 30608:C1RL
uniprot id: A0A8B7X664
uniprot id: A0A8B7X666
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:APC
gene id: 30608:APC
uniprot id: A0A8B7G9N5
uniprot id: A0A8B7G9N8
uniprot id: A0A8B7G9P1
uniprot id: A0A8B7G9P4
uniprot id: A0A8B7G9Z5
uniprot id: A0A8B7GAA7
uniprot id: A0A8C5UJU6
names: Similarity
messages: Belongs to the adenomatous polyposis coli (APC) family.

30608:C17H16orf62
gene id: 30608:C17H16orf62
uniprot id: A0A8B7EDT2
uniprot id: A0A8C5VKT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS35L family.
messages: Endosome

30608:GCNT4
gene id: 30608:GCNT4
uniprot id: A0A8C5V940
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

30608:BTC
gene id: 30608:BTC
uniprot id: A0A8C5VNF7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:MITF
gene id: 30608:MITF
uniprot id: A0A8B7HXE5
uniprot id: A0A8B7HXE9
uniprot id: A0A8B7HXF6
uniprot id: A0A8B7HXG9
uniprot id: A0A8B7HZI0
uniprot id: A0A8B7HZI5
uniprot id: A0A8B7I004
uniprot id: A0A8B7I010
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

30608:LOC105862254
gene id: 30608:LOC105862254
uniprot id: A0A8B7F7N1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

30608:SARAF
gene id: 30608:SARAF
uniprot id: A0A8B7HPA6
uniprot id: A0A8C5VPU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SARAF family.
messages: Endoplasmic reticulum membrane
messages: Interacts with STIM1; the interaction is inhibit by th interaction of STIM1 with EFHB.
messages: Membrane
messages: Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions.

30608:LOC105858789
gene id: 30608:LOC105858789
uniprot id: A0A8B7ER83
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

30608:MRPS21
gene id: 30608:MRPS21
uniprot id: A0A8C5V9L5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

30608:MRM1
gene id: 30608:MRM1
uniprot id: A0A8C5UNV3
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

30608:NOSIP
gene id: 30608:NOSIP
uniprot id: A0A8C5VU77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOSIP family.
messages: Cytoplasm
messages: Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.
messages: Nucleus

30608:LOC105872747
gene id: 30608:LOC105872747
uniprot id: A0A8B7GIM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:THOP1
gene id: 30608:THOP1
uniprot id: A0A8B7GP75
uniprot id: A0A8B7GQD2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

30608:GORASP2
gene id: 30608:GORASP2
uniprot id: A0A8B7HJ35
names: Similarity
messages: Belongs to the GORASP family.

30608:LHX3
gene id: 30608:LHX3
uniprot id: A0A8B7HLT5
uniprot id: A0A8B7XAH7
uniprot id: A0A8C5VX99
names: Subcellular Location Annotation
messages: Nucleus

30608:MEX3A
gene id: 30608:MEX3A
uniprot id: A0A8B7GK79
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:RNASE11
gene id: 30608:RNASE11
uniprot id: W0UVC0
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

30608:FAM178B
gene id: 30608:FAM178B
uniprot id: A0A8B7HWA3
uniprot id: A0A8B7HYQ3
uniprot id: A0A8B7X2V5
uniprot id: A0A8B7X3N9
names: Similarity
messages: Belongs to the FAM178 family.

30608:KDM5B
gene id: 30608:KDM5B
uniprot id: A0A8B7EWW0
uniprot id: A0A8B7EYT2
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

30608:RPS15
gene id: 30608:RPS15
uniprot id: A0A8C5XN52
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Component of the small ribosomal subunit.

30608:ATP9B
gene id: 30608:ATP9B
uniprot id: A0A8B7I157
uniprot id: A0A8B7I166
uniprot id: A0A8B7I170
uniprot id: A0A8B7I3A3
uniprot id: A0A8B7I408
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

30608:POU2F1
gene id: 30608:POU2F1
uniprot id: A0A8B7HNI9
uniprot id: A0A8B7HNJ4
uniprot id: A0A8B7HNJ9
uniprot id: A0A8B7HNK0
uniprot id: A0A8B7HNK1
uniprot id: A0A8B7HQ65
uniprot id: A0A8B7HQ75
uniprot id: A0A8B7HR08
uniprot id: A0A8B7HR13
uniprot id: A0A8B7HR20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus
messages: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR.

30608:ENTPD4
gene id: 30608:ENTPD4
uniprot id: A0A8B7EJR9
uniprot id: A0A8B7EKL1
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

30608:APOBEC1
gene id: 30608:APOBEC1
uniprot id: A0A8B7H8V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Nucleus

30608:CAMP
gene id: 30608:CAMP
uniprot id: A0A8B7GT92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Exhibits antimicrobial activity against E.coli and B.megaterium (in vitro).
messages: Secreted
messages: Vesicle

30608:LOC105869407
gene id: 30608:LOC105869407
uniprot id: A0A8B7X8B9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

30608:SPP1
gene id: 30608:SPP1
uniprot id: A0A8B7WY08
uniprot id: A0A8C5XS51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the osteopontin family.
messages: Secreted

30608:PICK1
gene id: 30608:PICK1
uniprot id: A0A8B7EQM5
uniprot id: A0A8B7ESB8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competitive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
messages: cytoskeleton
messages: perinuclear region
messages: synaptosome

30608:POLR1C
gene id: 30608:POLR1C
uniprot id: A0A8B7GY32
uniprot id: A0A8B7GY81
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

30608:TSPAN19
gene id: 30608:TSPAN19
uniprot id: A0A8B7EN27
uniprot id: A0A8B7EN34
uniprot id: A0A8B7EPL1
uniprot id: A0A8B7EQA5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:USP37
gene id: 30608:USP37
uniprot id: A0A8B7ELK3
uniprot id: A0A8B7EMY1
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

30608:LOC105870202
gene id: 30608:LOC105870202
uniprot id: A0A8B7G7P0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

30608:FA2H
gene id: 30608:FA2H
uniprot id: A0A8B7GWM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis. Involved in the synthesis of sphingolipids of plasma membrane rafts, controlling lipid raft mobility and trafficking of raft-associated proteins.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:ITGAL
gene id: 30608:ITGAL
uniprot id: A0A8B7GAV0
uniprot id: A0A8B7GBA3
uniprot id: A0A8B7GBW3
uniprot id: A0A8B7WNU0
uniprot id: A0A8C5W056
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

30608:DDX24
gene id: 30608:DDX24
uniprot id: A0A8C5XND1
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

30608:GGH
gene id: 30608:GGH
uniprot id: A0A8B7EPU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

30608:RNF10
gene id: 30608:RNF10
uniprot id: A0A8B7FSF9
uniprot id: A0A8C5VD13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF10 family.
messages: Cytoplasm

30608:LOC105873013
gene id: 30608:LOC105873013
uniprot id: A0A8B7GJ98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL42 family.
messages: Mitochondrion

30608:BEX3
gene id: 30608:BEX3
uniprot id: A0A8C5Y1Z7
names: Similarity
messages: Belongs to the BEX family.

30608:FGD6
gene id: 30608:FGD6
uniprot id: A0A8B7X6B0
names: Subcellular Location Annotation
messages: cytoskeleton

30608:BORCS5
gene id: 30608:BORCS5
uniprot id: A0A8B7H1A9
uniprot id: A0A8B7H1G5
uniprot id: A0A8B7H3C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS5 family.
messages: Lysosome membrane
messages: Membrane

30608:SMC5
gene id: 30608:SMC5
uniprot id: A0A8B7XCY9
uniprot id: A0A8C5WBG7
uniprot id: A0A8C6EJJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Chromosome
messages: Nucleus

30608:CCND2
gene id: 30608:CCND2
uniprot id: A0A8B7HNB1
names: Similarity
messages: Belongs to the cyclin family.

30608:EGF
gene id: 30608:EGF
uniprot id: A0A8B7GGC8
names: Caution
names: Function
names: Subunit
messages: EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
messages: Interacts with EGFR and promotes EGFR dimerization.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:RAD51
gene id: 30608:RAD51
uniprot id: A0A8B7GH89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Recruited to resolve stalled replication forks during replication stress. Also involved in interstrand cross-link repair.

30608:LOC105878952
gene id: 30608:LOC105878952
uniprot id: A0A8B7FEY4
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:ATAD2B
gene id: 30608:ATAD2B
uniprot id: A0A8B7I1R1
names: Similarity
messages: Belongs to the AAA ATPase family.

30608:LOC105859703
gene id: 30608:LOC105859703
uniprot id: A0A8B7EVB5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:ZC3HAV1
gene id: 30608:ZC3HAV1
uniprot id: A0A8B7GKD4
uniprot id: A0A8B7GKP7
uniprot id: A0A8B7GL04
uniprot id: A0A8B7GLJ3
names: Similarity
messages: Belongs to the ARTD/PARP family.

30608:SYS1
gene id: 30608:SYS1
uniprot id: A0A8B7HFA9
uniprot id: A0A8B7HFC8
uniprot id: A0A8B7HI02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYS1 family.
messages: Golgi apparatus membrane
messages: Interacts with ARFRP1.
messages: Involved in protein trafficking. May serve as a receptor for ARFRP1.
messages: Membrane

30608:LOC105880138
gene id: 30608:LOC105880138
uniprot id: A0A8B7HGX4
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

30608:TRIAP1
gene id: 30608:TRIAP1
uniprot id: A0A8B7FSL2
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

30608:PRPH2
gene id: 30608:PRPH2
uniprot id: A0A8B7H078
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRPH2/ROM1 family.
messages: Membrane

30608:AU129 gp06
gene id: 30608:AU129_gp06
uniprot id: Q94NN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
messages: Mitochondrion membrane

30608:ZSCAN9
gene id: 30608:ZSCAN9
uniprot id: A0A8C5Y953
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105864638
gene id: 30608:LOC105864638
uniprot id: A0A8B7FHZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CDKN1B
gene id: 30608:CDKN1B
uniprot id: A0A8C5Y3C8
names: Similarity
messages: Belongs to the CDI family.

30608:LOC105862378
gene id: 30608:LOC105862378
uniprot id: A0A8B7F877
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:NRM
gene id: 30608:NRM
uniprot id: A0A8B7EC80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Membrane
messages: Nucleus inner membrane

30608:LOC105881944
gene id: 30608:LOC105881944
uniprot id: A0A8B7HR83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:EIF4E1B
gene id: 30608:EIF4E1B
uniprot id: A0A8B7HKP5
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

30608:XIAP
gene id: 30608:XIAP
uniprot id: A0A8B7F285
names: Similarity
messages: Belongs to the IAP family.

30608:LOC105883433
gene id: 30608:LOC105883433
uniprot id: A0A8B7HXA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ADAMTS2
gene id: 30608:ADAMTS2
uniprot id: A0A8B7I3Q1
uniprot id: A0A8B7I3Q5
uniprot id: A0A8B7I5Q8
uniprot id: A0A8B7I6S4
uniprot id: A0A8B7I6T1
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:LOC105885787
gene id: 30608:LOC105885787
uniprot id: A0A8B7I6B9
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105878779
gene id: 30608:LOC105878779
uniprot id: A0A8B7HB45
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

30608:ACTR8
gene id: 30608:ACTR8
uniprot id: A0A8B7GUH4
uniprot id: A0A8B7GUM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP8 subfamily.
messages: Chromosome
messages: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.
messages: Nucleus
messages: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
messages: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

30608:RRAGC
gene id: 30608:RRAGC
uniprot id: A0A8B7HES4
uniprot id: A0A8C5USB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

30608:HTR2A
gene id: 30608:HTR2A
uniprot id: A0A8B7XF47
uniprot id: A0A8B7XFI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Presynapse
messages: Synapse
messages: Vesicle
messages: axon
messages: caveola
messages: dendrite

30608:NOC4L
gene id: 30608:NOC4L
uniprot id: A0A8B7HDZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: Nucleus membrane

30608:MTCP1
gene id: 30608:MTCP1
uniprot id: A0A8C5VA86
names: Similarity
messages: Belongs to the TCL1 family.

30608:LOC105855616
gene id: 30608:LOC105855616
uniprot id: A0A8B7XAP3
uniprot id: A0A8B7XBG5
names: Similarity
messages: Belongs to the FBPase class 1 family.

30608:PSMD13
gene id: 30608:PSMD13
uniprot id: A0A8B7GPR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S11 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits including PSMD13, a base containing 6 ATPases and few additional components.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

30608:ARMCX1
gene id: 30608:ARMCX1
uniprot id: A0A8B7WZG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eutherian X-chromosome-specific Armcx family.
messages: Membrane

30608:ANXA7
gene id: 30608:ANXA7
uniprot id: A0A8C5V154
uniprot id: A0A8C5VRM0
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

30608:TIGD7
gene id: 30608:TIGD7
uniprot id: A0A8B7EV87
names: Subcellular Location Annotation
messages: Nucleus

30608:DBNDD2
gene id: 30608:DBNDD2
uniprot id: A0A8B7HFJ2
names: Similarity
messages: Belongs to the dysbindin family.

30608:PHF19
gene id: 30608:PHF19
uniprot id: A0A8B7GUL7
uniprot id: A0A8B7GUM3
uniprot id: A0A8B7GUM4
uniprot id: A0A8B7GUM7
uniprot id: A0A8B7GUR1
uniprot id: A0A8B7GUR6
uniprot id: A0A8B7GUS7
uniprot id: A0A8B7GUT2
uniprot id: A0A8B7GUT4
uniprot id: A0A8B7GWF2
uniprot id: A0A8B7GWF7
uniprot id: A0A8B7XB90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

30608:SLC35A2
gene id: 30608:SLC35A2
uniprot id: A0A8B7EG67
uniprot id: A0A8B7EG68
uniprot id: A0A8B7EG73
uniprot id: A0A8B7EGM5
uniprot id: A0A8B7EGM8
uniprot id: A0A8B7EIM3
uniprot id: A0A8C5XC94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

30608:LOC105877834
gene id: 30608:LOC105877834
uniprot id: A0A8B7WW87
uniprot id: A0A8C6EK39
names: Function
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

30608:ELN
gene id: 30608:ELN
uniprot id: A0A8B7ERH6
uniprot id: A0A8B7ERH7
uniprot id: A0A8B7ERI1
uniprot id: A0A8B7ERI2
uniprot id: A0A8B7ERI9
uniprot id: A0A8B7ERJ4
uniprot id: A0A8B7ET98
uniprot id: A0A8B7ETJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elastin family.
messages: Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle.
messages: extracellular matrix

30608:TPM3
gene id: 30608:TPM3
uniprot id: A0A8B7IA62
uniprot id: A0A8B7WZX1
uniprot id: A0A8B7WZX3
uniprot id: A0A8B7WZX8
uniprot id: A0A8B7WZY5
uniprot id: A0A8B7X0F9
uniprot id: A0A8B7X0G8
uniprot id: A0A8B7X0H4
uniprot id: A0A8B7X111
uniprot id: A0A8B7X121
uniprot id: A0A8B7X127
uniprot id: A0A8B7X1M3
uniprot id: A0A8B7X1M7
uniprot id: A0A8B7X1N3
uniprot id: A0A8C5XDA1
uniprot id: A0A8C5Y2Z6
uniprot id: A0A8C5YH16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

30608:VMA21
gene id: 30608:VMA21
uniprot id: A0A8B7EBE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the V0 complex of the vacuolar ATPase (V-ATPase).
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

30608:PPFIBP2
gene id: 30608:PPFIBP2
uniprot id: A0A8B7EWD6
uniprot id: A0A8B7EWD7
uniprot id: A0A8B7EWE6
uniprot id: A0A8B7EWE7
uniprot id: A0A8B7EWE9
uniprot id: A0A8B7EWF5
uniprot id: A0A8B7EWF8
uniprot id: A0A8B7EWG0
uniprot id: A0A8B7EWG3
uniprot id: A0A8B7EWG4
uniprot id: A0A8B7EYB6
uniprot id: A0A8B7EYC0
uniprot id: A0A8B7EYC4
uniprot id: A0A8B7EYC9
uniprot id: A0A8B7EYD4
uniprot id: A0A8B7EYD8
uniprot id: A0A8B7EYF0
uniprot id: A0A8B7EYF5
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

30608:ELL3
gene id: 30608:ELL3
uniprot id: A0A8B7GHT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

30608:LOC105864569
gene id: 30608:LOC105864569
uniprot id: A0A8B7FHN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TLE4
gene id: 30608:TLE4
uniprot id: A0A8B7FAQ1
uniprot id: A0A8B7FAQ6
uniprot id: A0A8B7FAR1
uniprot id: A0A8B7FAR3
uniprot id: A0A8B7FAR8
uniprot id: A0A8B7FAS3
uniprot id: A0A8B7FAW4
uniprot id: A0A8B7FAW8
uniprot id: A0A8B7FAX3
uniprot id: A0A8B7FBC3
uniprot id: A0A8B7FBC8
uniprot id: A0A8B7FBD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

30608:PRRX2
gene id: 30608:PRRX2
uniprot id: A0A8B7GW21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

30608:VPS8
gene id: 30608:VPS8
uniprot id: A0A8B7ED50
names: Similarity
messages: Belongs to the VPS8 family.

30608:LOC109731087
gene id: 30608:LOC109731087
uniprot id: A0A8B7X9B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vexin family.
messages: Cell membrane
messages: Membrane
messages: Nucleus

30608:CFB
gene id: 30608:CFB
uniprot id: A0A8B7ENP3
uniprot id: A0A8C5XGC5
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:KIF4A
gene id: 30608:KIF4A
uniprot id: A0A8C5XE95
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:LOC105878066
gene id: 30608:LOC105878066
uniprot id: A0A8B7H803
uniprot id: A0A8B7H804
uniprot id: A0A8B7H825
uniprot id: A0A8B7HAL7
names: Similarity
messages: Belongs to the CENP-X/MHF2 family.

30608:ZC3H12A
gene id: 30608:ZC3H12A
uniprot id: A0A8B7HEH0
names: Similarity
messages: Belongs to the ZC3H12 family.

30608:LOC105871382
gene id: 30608:LOC105871382
uniprot id: A0A8B7EPX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:RSAD2
gene id: 30608:RSAD2
uniprot id: A0A8B7G8P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RSAD2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion outer membrane

30608:NOX1
gene id: 30608:NOX1
uniprot id: A0A8B7GIY7
uniprot id: A0A8B7GJL2
uniprot id: A0A8B7WYK7
uniprot id: A0A8B7WYL0
uniprot id: A0A8B7WZJ0
names: Subcellular Location Annotation
messages: Membrane

30608:CPVL
gene id: 30608:CPVL
uniprot id: A0A8B7EBC4
names: Similarity
messages: Belongs to the peptidase S10 family.

30608:LOC105863109
gene id: 30608:LOC105863109
uniprot id: A0A8B7FB03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NRCAM
gene id: 30608:NRCAM
uniprot id: A0A8B7F0I9
uniprot id: A0A8B7F0J2
uniprot id: A0A8B7F0P8
uniprot id: A0A8B7F0Q2
uniprot id: A0A8B7F0R4
uniprot id: A0A8B7F0S8
uniprot id: A0A8B7F0T3
uniprot id: A0A8B7F310
uniprot id: A0A8B7F354
uniprot id: A0A8B7XC22
uniprot id: A0A8B7XC23
uniprot id: A0A8B7XC27
uniprot id: A0A8B7XC28
uniprot id: A0A8B7XC32
uniprot id: A0A8B7XC33
uniprot id: A0A8B7XC36
uniprot id: A0A8B7XD21
uniprot id: A0A8B7XD27
uniprot id: A0A8B7XD34
uniprot id: A0A8B7XD39
uniprot id: A0A8B7XDS5
uniprot id: A0A8B7XDT0
uniprot id: A0A8B7XEA7
uniprot id: A0A8B7XEB2
uniprot id: A0A8B7XEB8
uniprot id: A0A8C5VQ74
uniprot id: A0A8C5XFK1
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

30608:CNIH1
gene id: 30608:CNIH1
uniprot id: A0A8B7FWW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

30608:TBXAS1
gene id: 30608:TBXAS1
uniprot id: A0A8B7GKF6
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:RBM10
gene id: 30608:RBM10
uniprot id: A0A8B7FAL8
uniprot id: A0A8B7FAL9
uniprot id: A0A8B7FAM3
uniprot id: A0A8B7FAM4
uniprot id: A0A8B7FAN2
uniprot id: A0A8B7FAU1
uniprot id: A0A8B7FB93
uniprot id: A0A8B7FB98
uniprot id: A0A8B7WYR5
names: Subcellular Location Annotation
messages: Nucleus

30608:HOXC9
gene id: 30608:HOXC9
uniprot id: A0A8C5XDN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

30608:PPP1R12C
gene id: 30608:PPP1R12C
uniprot id: A0A8B7H3X1
uniprot id: A0A8B7H413
uniprot id: A0A8B7H652
uniprot id: A0A8B7WV01
uniprot id: A0A8B7WWM0
names: Subcellular Location Annotation
names: Subunit
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.
messages: stress fiber

30608:TMTC3
gene id: 30608:TMTC3
uniprot id: A0A8B7FVH8
uniprot id: A0A8B7FVN5
uniprot id: A0A8B7FWH4
uniprot id: A0A8C5XKW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

30608:LOC105862837
gene id: 30608:LOC105862837
uniprot id: A0A8B7X5Q3
names: Similarity
messages: Belongs to the Luc7 family.

30608:LOC105883392
gene id: 30608:LOC105883392
uniprot id: A0A8B7HUZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SLC45A3
gene id: 30608:SLC45A3
uniprot id: A0A8B7G0L0
names: Subcellular Location Annotation
messages: Membrane

30608:EPCAM
gene id: 30608:EPCAM
uniprot id: A0A8C5VRW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lateral cell membrane
messages: May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
messages: Membrane
messages: tight junction

30608:ZFHX4
gene id: 30608:ZFHX4
uniprot id: A0A8B7EJC8
uniprot id: A0A8C5XQU7
names: Subcellular Location Annotation
messages: Nucleus

30608:TP53BP1
gene id: 30608:TP53BP1
uniprot id: A0A8B7GGY7
uniprot id: A0A8B7GHD5
uniprot id: A0A8B7GHN3
uniprot id: A0A8B7GHN8
uniprot id: A0A8B7GHT9
uniprot id: A0A8B7X1L7
names: Subcellular Location Annotation
messages: Nucleus

30608:IST1
gene id: 30608:IST1
uniprot id: A0A8B7ERX6
uniprot id: A0A8C5W2P4
uniprot id: A0A8C5XYI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IST1 family.
messages: Cytoplasmic vesicle
messages: Nucleus envelope

30608:LOC105883403
gene id: 30608:LOC105883403
uniprot id: A0A8B7HX70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105870617
gene id: 30608:LOC105870617
uniprot id: A0A8B7G8N7
uniprot id: A0A8B7G9S8
uniprot id: A0A8B7G9T2
uniprot id: A0A8C5XJJ2
names: Similarity
messages: Belongs to the perilipin family.

30608:LOC105879067
gene id: 30608:LOC105879067
uniprot id: A0A8B7HCC5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

30608:SLC25A33
gene id: 30608:SLC25A33
uniprot id: A0A8B7I7E3
uniprot id: A0A8B7I7H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:BMPR2
gene id: 30608:BMPR2
uniprot id: A0A8B7EJH1
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

30608:LOXL2
gene id: 30608:LOXL2
uniprot id: A0A8B7EJE5
uniprot id: A0A8B7EJR4
uniprot id: A0A8B7WSV3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

30608:LOC105861766
gene id: 30608:LOC105861766
uniprot id: A0A8B7WSX4
uniprot id: A0A8C5V4D5
names: Similarity
messages: Belongs to the CLCR family.

30608:GPR141
gene id: 30608:GPR141
uniprot id: A0A8B7HBE6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:DNAJC2
gene id: 30608:DNAJC2
uniprot id: A0A8B7F4E5
uniprot id: A0A8B7F4F6
uniprot id: A0A8B7F4G5
names: Function
names: Subcellular Location Annotation
messages: Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation.
messages: cytosol

30608:SNX21
gene id: 30608:SNX21
uniprot id: A0A8B7EV66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Membrane

30608:SUOX
gene id: 30608:SUOX
uniprot id: A0A8B7FKI6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the oxidation of sulfite to sulfate, the terminal reaction in the oxidative degradation of sulfur-containing amino acids.
messages: Homodimer.
messages: Mitochondrion intermembrane space

30608:SLCO4C1
gene id: 30608:SLCO4C1
uniprot id: A0A8B7GZB1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:GPR21
gene id: 30608:GPR21
uniprot id: A0A8B7GV38
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:LOC105878427
gene id: 30608:LOC105878427
uniprot id: A0A8B7WNE6
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:SLC10A5
gene id: 30608:SLC10A5
uniprot id: A0A8B7ELA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

30608:LOC105883866
gene id: 30608:LOC105883866
uniprot id: A0A8C5VDY8
names: Similarity
messages: Belongs to the Schlafen family. Subgroup III subfamily.

30608:RBBP4
gene id: 30608:RBBP4
uniprot id: A0A8B7GER5
names: Subcellular Location Annotation
messages: Nucleus

30608:FMO5
gene id: 30608:FMO5
uniprot id: A0A8B7G6H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as Baeyer-Villiger monooxygenase on a broad range of substrates. Catalyzes the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters.
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

30608:METTL2A
gene id: 30608:METTL2A
uniprot id: A0A8B7F556
uniprot id: A0A8C5Y060
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

30608:LCLAT1
gene id: 30608:LCLAT1
uniprot id: A0A8B7HZU7
uniprot id: A0A8B7I1Y3
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

30608:DIAPH1
gene id: 30608:DIAPH1
uniprot id: A0A8B7F8X9
uniprot id: A0A8B7F8Y0
uniprot id: A0A8B7F928
names: Similarity
messages: Belongs to the formin homology family. Diaphanous subfamily.

30608:TSHZ3
gene id: 30608:TSHZ3
uniprot id: A0A8B7H334
uniprot id: A0A8B7H596
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

30608:SCN3B
gene id: 30608:SCN3B
uniprot id: A0A8B7I3F7
uniprot id: A0A8B7I5F9
uniprot id: A0A8B7I5G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.
messages: Membrane
messages: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.

30608:CD68
gene id: 30608:CD68
uniprot id: A0A8C5V1Y6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

30608:ESYT1
gene id: 30608:ESYT1
uniprot id: A0A8B7FJP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:PLG
gene id: 30608:PLG
uniprot id: A0A8B7FZR6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Converted into plasmin by plasminogen activators, both plasminogen and its activator being bound to fibrin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.
messages: Secreted

30608:SMAD2
gene id: 30608:SMAD2
uniprot id: A0A8B7EZC2
uniprot id: A0A8B7F143
uniprot id: A0A8C5Y442
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

30608:DNPEP
gene id: 30608:DNPEP
uniprot id: A0A8B7ELE1
uniprot id: A0A8B7EMS4
uniprot id: A0A8B7ENP2
names: Similarity
names: Subunit
messages: Belongs to the peptidase M18 family.
messages: Tetrahedron-shaped homododecamer built from six homodimers.

30608:LOC105862438
gene id: 30608:LOC105862438
uniprot id: A0A8B7F8L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:FAM46A
gene id: 30608:FAM46A
uniprot id: A0A8B7GNC2
uniprot id: A0A8C5VMH4
names: Similarity
messages: Belongs to the TENT family.

30608:CDK2
gene id: 30608:CDK2
uniprot id: A0A8B7FJD1
uniprot id: A0A8C5XM31
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:LOC105869720
gene id: 30608:LOC105869720
uniprot id: A0A8B7G4U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MFSD4B
gene id: 30608:MFSD4B
uniprot id: A0A8B7FIX7
names: Subcellular Location Annotation
messages: Membrane

30608:GATC
gene id: 30608:GATC
uniprot id: A0A8C5XCX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

30608:OTOP1
gene id: 30608:OTOP1
uniprot id: A0A8B7EK95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

30608:TMEM170A
gene id: 30608:TMEM170A
uniprot id: A0A8B7GWP3
uniprot id: A0A8B7GWQ3
uniprot id: A0A8B7GYJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

30608:FRZB
gene id: 30608:FRZB
uniprot id: A0A8C5Y7H1
names: Caution
names: Function
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.

30608:LOC105875154
gene id: 30608:LOC105875154
uniprot id: A0A8B7XDH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105873313
gene id: 30608:LOC105873313
uniprot id: A0A8B7GKR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ACP7
gene id: 30608:ACP7
uniprot id: A0A8B7H1T3
uniprot id: A0A8C5V1L3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.

30608:TAS2R41
gene id: 30608:TAS2R41
uniprot id: A0A8B7GKY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

30608:NR1H3
gene id: 30608:NR1H3
uniprot id: A0A8B7I1V6
uniprot id: A0A8B7I3V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

30608:CLUAP1
gene id: 30608:CLUAP1
uniprot id: A0A8B7EX79
uniprot id: A0A8B7EX81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLUAP1 family.
messages: cilium

30608:C12H5orf63
gene id: 30608:C12H5orf63
uniprot id: A0A8B7E9T2
names: Similarity
messages: Belongs to the glutaredoxin family.

30608:POLE2
gene id: 30608:POLE2
uniprot id: A0A8B7FVL6
uniprot id: A0A8B7FVL8
uniprot id: A0A8B7FVS8
uniprot id: A0A8B7X277
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase epsilon subunit B family.
messages: Nucleus
messages: Participates in DNA repair and in chromosomal DNA replication.

30608:PPM1E
gene id: 30608:PPM1E
uniprot id: A0A8B7GJQ9
names: Similarity
messages: Belongs to the PP2C family.

30608:S1PR1
gene id: 30608:S1PR1
uniprot id: A0A8B7F7N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105860521
gene id: 30608:LOC105860521
uniprot id: A0A8C5YHH1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:DHODH
gene id: 30608:DHODH
uniprot id: A0A8B7WRY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. Required for UMP biosynthesis via de novo pathway.
messages: Mitochondrion inner membrane

30608:LEF1
gene id: 30608:LEF1
uniprot id: A0A8B7GG29
uniprot id: A0A8B7GGI6
uniprot id: A0A8B7WXT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

30608:CA10
gene id: 30608:CA10
uniprot id: A0A8C6EIT6
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Does not have a catalytic activity.

30608:FUCA1
gene id: 30608:FUCA1
uniprot id: A0A8B7FCZ5
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

30608:PTGFR
gene id: 30608:PTGFR
uniprot id: A0A8B7HZA9
uniprot id: A0A8B7HZS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:GALT
gene id: 30608:GALT
uniprot id: A0A8C5VV79
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.

30608:LOC105869722
gene id: 30608:LOC105869722
uniprot id: A0A8B7G670
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CPAMD8
gene id: 30608:CPAMD8
uniprot id: A0A8B7WVG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

30608:IAH1
gene id: 30608:IAH1
uniprot id: A0A8B7HT06
uniprot id: A0A8B7HT19
uniprot id: A0A8B7HV32
uniprot id: A0A8B7XB38
uniprot id: A0A8C5UN05
names: Function
names: Similarity
messages: Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
messages: Probable lipase.

30608:SLC15A3
gene id: 30608:SLC15A3
uniprot id: A0A8B7HDG3
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

30608:CACNA1S
gene id: 30608:CACNA1S
uniprot id: A0A8B7WYT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.

30608:ARL5C
gene id: 30608:ARL5C
uniprot id: A0A8B7GG10
uniprot id: A0A8B7GG18
uniprot id: A0A8C5URN8
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

30608:SYNDIG1L
gene id: 30608:SYNDIG1L
uniprot id: A0A8B7EQU2
names: Similarity
messages: Belongs to the CD225/Dispanin family.

30608:TMEM161B
gene id: 30608:TMEM161B
uniprot id: A0A8B7HI14
uniprot id: A0A8B7HIY7
uniprot id: A0A8B7XD76
uniprot id: A0A8C5XFF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

30608:ST6GALNAC2
gene id: 30608:ST6GALNAC2
uniprot id: A0A8B7HEN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

30608:STS
gene id: 30608:STS
uniprot id: A0A8B7HKC6
uniprot id: A0A8B7HLJ7
uniprot id: A0A8C5Y6Z1
names: Similarity
messages: Belongs to the sulfatase family.

30608:CRX
gene id: 30608:CRX
uniprot id: A0A8B7G4D9
names: Subcellular Location Annotation
messages: Nucleus

30608:CLIC6
gene id: 30608:CLIC6
uniprot id: A0A8B7HNX2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

30608:FAT1
gene id: 30608:FAT1
uniprot id: A0A8B7HSX1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:VPS37A
gene id: 30608:VPS37A
uniprot id: A0A8B7HRF2
uniprot id: A0A8B7HTR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

30608:LOC105864005
gene id: 30608:LOC105864005
uniprot id: A0A8B7FFM7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

30608:NR2C1
gene id: 30608:NR2C1
uniprot id: A0A8C5W9N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

30608:NUP210
gene id: 30608:NUP210
uniprot id: A0A8B7FHD1
uniprot id: A0A8B7FHG3
uniprot id: A0A8B7FHL1
uniprot id: A0A8B7FIP0
uniprot id: A0A8B7WWP6
names: Similarity
messages: Belongs to the NUP210 family.

30608:FAM189A2
gene id: 30608:FAM189A2
uniprot id: A0A8B7XBK1
names: Similarity
messages: Belongs to the ENTREP family.

30608:DOPEY1
gene id: 30608:DOPEY1
uniprot id: A0A8B7GPS0
names: Similarity
messages: Belongs to the dopey family.

30608:RPA2
gene id: 30608:RPA2
uniprot id: A0A8B7WLS1
names: Similarity
messages: Belongs to the replication factor A protein 2 family.

30608:LPIN1
gene id: 30608:LPIN1
uniprot id: A0A8B7X754
names: Similarity
messages: Belongs to the lipin family.

30608:ACTG2
gene id: 30608:ACTG2
uniprot id: A0A8C5W9U8
names: Similarity
messages: Belongs to the actin family.

30608:CMTM6
gene id: 30608:CMTM6
uniprot id: A0A8C5YHK7
names: Subcellular Location Annotation
messages: Membrane

30608:GNAT1
gene id: 30608:GNAT1
uniprot id: A0A8C6EJT5
names: Similarity
messages: Belongs to the G-alpha family. G(i/o/t/z) subfamily.

30608:SLC7A13
gene id: 30608:SLC7A13
uniprot id: A0A8B7H0T0
uniprot id: A0A8B7H0U2
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105884084
gene id: 30608:LOC105884084
uniprot id: A0A8B7HYE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NEU1
gene id: 30608:NEU1
uniprot id: A0A8B7ENU9
uniprot id: A0A8B7ENY9
uniprot id: A0A8B7EQD5
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

30608:APCS
gene id: 30608:APCS
uniprot id: A0A8C5XZS3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Secreted

30608:LOC105881621
gene id: 30608:LOC105881621
uniprot id: A0A8B7HMA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:RNPS1
gene id: 30608:RNPS1
uniprot id: A0A8B7EV17
uniprot id: A0A8B7EX10
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the splicing factor SR family.
messages: Found in mRNA splicing-dependent exon junction complexes (EJC). Found in a post-splicing complex with NXF1, RBM8A, UPF1, UPF2, UPF3A, UPF3B and RNPS1. Component of the heterotrimeric ASAP (apoptosis- and splicing-associated protein) and PSAP complexes consisting of RNPS1, SAP18 and either ACIN1 or PNN, respectively; the ASAP and PSAP complexes probably are formed mutually exclusive. Component of the active spliceosome. Associates with polysomes. Interacts with the cleaved p110 isoform of CDC2L1, CSNK2A1, PNN, SART3, SRP54, SRRM1 and TRA2B/SFRS10.
messages: Nucleus speckle

30608:LZTS2
gene id: 30608:LZTS2
uniprot id: A0A8B7GN34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTS2 family.
messages: Cytoplasm
messages: Interacts with KATNB1. Also interacts with CTNNB1, gamma-tubulin and KIF23.
messages: Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
messages: centrosome

30608:NONO
gene id: 30608:NONO
uniprot id: A0A8B7EBH8
names: Subcellular Location Annotation
messages: Nucleus speckle

30608:TSSC1
gene id: 30608:TSSC1
uniprot id: A0A8B7G9D9
uniprot id: A0A8B7X946
uniprot id: A0A8B7XAR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EIPR1 family.
messages: trans-Golgi network

30608:CHMP4C
gene id: 30608:CHMP4C
uniprot id: A0A8B7EKZ5
names: Similarity
messages: Belongs to the SNF7 family.

30608:TMEM254
gene id: 30608:TMEM254
uniprot id: A0A8B7G6S0
names: Subcellular Location Annotation
messages: Membrane

30608:SCN1A
gene id: 30608:SCN1A
uniprot id: A0A8B7FTQ7
uniprot id: A0A8B7FUD2
uniprot id: A0A8B7FUM1
uniprot id: A0A8B7X8B3
uniprot id: A0A8B7XAB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

30608:FAM96A
gene id: 30608:FAM96A
uniprot id: A0A8C5W8F0
names: Similarity
messages: Belongs to the MIP18 family.

30608:ADGRB1
gene id: 30608:ADGRB1
uniprot id: A0A8B7FFR6
uniprot id: A0A8B7FFS2
uniprot id: A0A8B7FFU4
uniprot id: A0A8B7FG05
uniprot id: A0A8B7FGW9
uniprot id: A0A8B7XBT2
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105863858
gene id: 30608:LOC105863858
uniprot id: A0A8B7FEU5
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

30608:LOC105873530
gene id: 30608:LOC105873530
uniprot id: A0A8B7HL84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

30608:ATP6V1A
gene id: 30608:ATP6V1A
uniprot id: A0A8B7HXQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Vesicle
messages: clathrin-coated vesicle membrane
messages: secretory vesicle

30608:OLFM3
gene id: 30608:OLFM3
uniprot id: A0A8B7F7M6
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

30608:ATP1A1
gene id: 30608:ATP1A1
uniprot id: A0A8C5XIQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Membrane

30608:FBLN7
gene id: 30608:FBLN7
uniprot id: A0A8B7EV06
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105859923
gene id: 30608:LOC105859923
uniprot id: A0A8B7EYG5
uniprot id: A0A8C5VBL0
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

30608:B3GNT6
gene id: 30608:B3GNT6
uniprot id: A0A8B7EYJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:LOC105881046
gene id: 30608:LOC105881046
uniprot id: A0A8B7HKD5
names: Subcellular Location Annotation
messages: Nucleus

30608:CDKN1C
gene id: 30608:CDKN1C
uniprot id: A0A8C5XGX7
names: Similarity
messages: Belongs to the CDI family.

30608:NXPH2
gene id: 30608:NXPH2
uniprot id: A0A8B7ELI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

30608:NUF2
gene id: 30608:NUF2
uniprot id: A0A8C5VIC7
names: Similarity
messages: Belongs to the NUF2 family.

30608:AGXT
gene id: 30608:AGXT
uniprot id: A0A8C5XJQ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Peroxisome

30608:STX12
gene id: 30608:STX12
uniprot id: A0A8C5W500
names: Similarity
messages: Belongs to the syntaxin family.

30608:THOC5
gene id: 30608:THOC5
uniprot id: A0A8B7G9W4
uniprot id: A0A8B7WUN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC5 family.
messages: Nucleus

30608:JAG1
gene id: 30608:JAG1
uniprot id: A0A8C5VSL3
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

30608:RAX2
gene id: 30608:RAX2
uniprot id: A0A8B7GPB3
names: Subcellular Location Annotation
messages: Nucleus

30608:CAB39L
gene id: 30608:CAB39L
uniprot id: A0A8B7XFI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

30608:LOC105866780
gene id: 30608:LOC105866780
uniprot id: A0A8B7FT23
names: Subcellular Location Annotation
messages: Membrane

30608:TMEM41B
gene id: 30608:TMEM41B
uniprot id: A0A8B7HNZ2
uniprot id: A0A8B7HQL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

30608:CPN1
gene id: 30608:CPN1
uniprot id: A0A8C5USX6
names: Similarity
messages: Belongs to the peptidase M14 family.

30608:LOC105872488
gene id: 30608:LOC105872488
uniprot id: A0A8C5UR30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

30608:RDH8
gene id: 30608:RDH8
uniprot id: A0A8B7I8N0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:TBL3
gene id: 30608:TBL3
uniprot id: A0A8C5W914
names: Subcellular Location Annotation
messages: nucleolus

30608:WNT8A
gene id: 30608:WNT8A
uniprot id: A0A8B7F915
uniprot id: A0A8B7WR20
uniprot id: A0A8B7WR22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

30608:ABCA12
gene id: 30608:ABCA12
uniprot id: A0A8B7FTZ4
names: Subcellular Location Annotation
messages: Membrane

30608:CSRNP2
gene id: 30608:CSRNP2
uniprot id: A0A8C5XTV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

30608:FUCA2
gene id: 30608:FUCA2
uniprot id: A0A8B7GLS7
uniprot id: A0A8B7GM44
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

30608:WDR82
gene id: 30608:WDR82
uniprot id: A0A8B7GUB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SWD2 family.
messages: Nucleus

30608:FMO2
gene id: 30608:FMO2
uniprot id: A0A8B7GD92
uniprot id: A0A8B7GDT6
uniprot id: A0A8C5VJF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

30608:XCR1
gene id: 30608:XCR1
uniprot id: A0A8B7GRS5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:GTF2A1
gene id: 30608:GTF2A1
uniprot id: A0A8B7FXG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

30608:SERPINB9
gene id: 30608:SERPINB9
uniprot id: A0A8B7GM60
uniprot id: A0A8C5VJB2
names: Similarity
messages: Belongs to the serpin family. Ov-serpin subfamily.

30608:OPRL1
gene id: 30608:OPRL1
uniprot id: A0A8B7GZU2
uniprot id: A0A8B7WQB2
uniprot id: A0A8B7WQB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
messages: Membrane
messages: Vesicle

30608:MED22
gene id: 30608:MED22
uniprot id: A0A8B7HKF4
uniprot id: A0A8B7HLW2
names: Function
names: Subcellular Location Annotation
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

30608:LOC105881817
gene id: 30608:LOC105881817
uniprot id: A0A8B7HPV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

30608:ANP32E
gene id: 30608:ANP32E
uniprot id: A0A8B7WWP7
uniprot id: A0A8B7WXG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANP32 family.
messages: Multifunctional protein that is involved in the regulation of many processes.
messages: Nucleus

30608:ATP2B2
gene id: 30608:ATP2B2
uniprot id: A0A8B7HRX2
uniprot id: A0A8B7HRY3
uniprot id: A0A8B7HRZ5
uniprot id: A0A8B7HTX8
uniprot id: A0A8B7WWV1
uniprot id: A0A8C5VMF3
uniprot id: A0A8C6EJ44
uniprot id: A0A8C6EJR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:C21H12orf43
gene id: 30608:C21H12orf43
uniprot id: A0A8B7FSR1
uniprot id: A0A8C5XW42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUSTOS family.
messages: Nucleus envelope

30608:CDH24
gene id: 30608:CDH24
uniprot id: A0A8B7FIF0
uniprot id: A0A8B7FJL9
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

30608:SNRPA
gene id: 30608:SNRPA
uniprot id: A0A8B7H1H1
uniprot id: A0A8B7H1H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM U1 A/B'' family.
messages: Nucleus

30608:HS6ST2
gene id: 30608:HS6ST2
uniprot id: A0A8B7GC94
uniprot id: A0A8B7GC95
uniprot id: A0A8B7GCV2
uniprot id: A0A8B7GCV8
uniprot id: A0A8B7GD81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

30608:LOC105859911
gene id: 30608:LOC105859911
uniprot id: A0A8C5VDZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:EYA4
gene id: 30608:EYA4
uniprot id: A0A8B7HL89
uniprot id: A0A8B7X4X9
uniprot id: A0A8B7X4Y3
uniprot id: A0A8B7X4Y4
uniprot id: A0A8B7X4Y9
uniprot id: A0A8B7X5J2
uniprot id: A0A8B7X6N4
uniprot id: A0A8B7X6N9
uniprot id: A0A8B7X6T6
uniprot id: A0A8B7X6U1
uniprot id: A0A8C5YAH4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

30608:ARHGDIG
gene id: 30608:ARHGDIG
uniprot id: A0A8C5XDA5
names: Similarity
messages: Belongs to the Rho GDI family.

30608:ABHD3
gene id: 30608:ABHD3
uniprot id: A0A8C5WB66
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

30608:DNASE1L2
gene id: 30608:DNASE1L2
uniprot id: A0A8B7EUZ2
uniprot id: A0A8B7EUZ4
uniprot id: A0A8B7EV03
uniprot id: A0A8B7EWZ2
uniprot id: A0A8B7EWZ3
names: Similarity
messages: Belongs to the DNase I family.

30608:AP4B1
gene id: 30608:AP4B1
uniprot id: A0A8B7HAX4
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

30608:HADH
gene id: 30608:HADH
uniprot id: A0A8B7GG25
uniprot id: A0A8B7GG34
uniprot id: A0A8C5VHV5
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

30608:BCL2A1
gene id: 30608:BCL2A1
uniprot id: A0A8B7FH37
names: Similarity
messages: Belongs to the Bcl-2 family.

30608:LYG2
gene id: 30608:LYG2
uniprot id: A0A8B7X2W4
uniprot id: A0A8C5XZZ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 23 family.

30608:PDE11A
gene id: 30608:PDE11A
uniprot id: A0A8B7HTH1
uniprot id: A0A8B7HTI0
uniprot id: A0A8B7HVP6
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

30608:POT1
gene id: 30608:POT1
uniprot id: A0A8C5VMK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the telombin family.
messages: Nucleus
messages: telomere

30608:NGLY1
gene id: 30608:NGLY1
uniprot id: A0A8B7HUG5
uniprot id: A0A8C5YF88
uniprot id: A0A8C5YI42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglutaminase-like superfamily. PNGase family.
messages: Cytoplasm
messages: Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins.

30608:LOC109731337
gene id: 30608:LOC109731337
uniprot id: A0A8B7XDB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TLX2
gene id: 30608:TLX2
uniprot id: A0A8B7I0F5
names: Subcellular Location Annotation
messages: Nucleus

30608:CBFA2T3
gene id: 30608:CBFA2T3
uniprot id: A0A8B7EDS4
uniprot id: A0A8B7EED9
uniprot id: A0A8B7EGD3
names: Similarity
messages: Belongs to the CBFA2T family.

30608:DESI1
gene id: 30608:DESI1
uniprot id: A0A8C6EII1
names: Similarity
messages: Belongs to the DeSI family.

30608:MS4A15
gene id: 30608:MS4A15
uniprot id: A0A8C5V9A0
names: Similarity
messages: Belongs to the MS4A family.

30608:LOC105860376
gene id: 30608:LOC105860376
uniprot id: A0A8B7EYP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NOTCH4
gene id: 30608:NOTCH4
uniprot id: A0A8B7ENK7
uniprot id: A0A8B7ENR5
uniprot id: A0A8B7EQ49
uniprot id: A0A8B7EQR2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

30608:MRPS31
gene id: 30608:MRPS31
uniprot id: A0A8C5XCD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS31 family.
messages: Mitochondrion

30608:ASF1B
gene id: 30608:ASF1B
uniprot id: A0A8C5YFF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

30608:MVK
gene id: 30608:MVK
uniprot id: A0A8B7FSE0
uniprot id: A0A8B7FTC1
uniprot id: A0A8C5V6F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis.
messages: Cytoplasm

30608:TRIM71
gene id: 30608:TRIM71
uniprot id: A0A8B7GP30
names: Similarity
messages: Belongs to the TRIM/RBCC family.

30608:LOC105883354
gene id: 30608:LOC105883354
uniprot id: A0A8B7HUV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:EXT1
gene id: 30608:EXT1
uniprot id: A0A8B7FE59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:PPP1R15B
gene id: 30608:PPP1R15B
uniprot id: A0A8B7FZU6
names: Similarity
messages: Belongs to the PPP1R15 family.

30608:GPR37
gene id: 30608:GPR37
uniprot id: A0A8B7I4H5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:ALG5
gene id: 30608:ALG5
uniprot id: A0A8B7F6V6
uniprot id: A0A8C5Y8T3
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

30608:PANK1
gene id: 30608:PANK1
uniprot id: A0A8B7GEF1
names: Subcellular Location Annotation
messages: Nucleus

30608:FUBP1
gene id: 30608:FUBP1
uniprot id: A0A8B7HXI3
uniprot id: A0A8B7WRW3
uniprot id: A0A8B7WRX6
uniprot id: A0A8B7WRY1
uniprot id: A0A8B7WRY6
uniprot id: A0A8B7WRY9
uniprot id: A0A8B7WRZ0
uniprot id: A0A8B7WS04
uniprot id: A0A8B7WS05
uniprot id: A0A8B7WS09
uniprot id: A0A8B7WS15
uniprot id: A0A8B7WS21
uniprot id: A0A8B7WS27
uniprot id: A0A8B7WTE4
uniprot id: A0A8B7WTF8
uniprot id: A0A8B7WTG2
uniprot id: A0A8B7WTG7
names: Subcellular Location Annotation
messages: Nucleus

30608:MAMDC4
gene id: 30608:MAMDC4
uniprot id: A0A8B7HQ85
uniprot id: A0A8B7HQ87
uniprot id: A0A8B7HS10
uniprot id: A0A8B7XCG0
uniprot id: A0A8B7XDR3
uniprot id: A0A8C5VG98
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:HMBS
gene id: 30608:HMBS
uniprot id: A0A8C5W191
names: Similarity
messages: Belongs to the HMBS family.

30608:GDI2
gene id: 30608:GDI2
uniprot id: A0A8B7EQH6
uniprot id: A0A8B7WWF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

30608:SSR4
gene id: 30608:SSR4
uniprot id: A0A8B7FU02
uniprot id: A0A8B7FU04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-delta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

30608:PCYT2
gene id: 30608:PCYT2
uniprot id: A0A8B7I2D6
uniprot id: A0A8B7I2E9
uniprot id: A0A8B7I5D2
uniprot id: A0A8C5V9N6
names: Similarity
messages: Belongs to the cytidylyltransferase family.

30608:LOC105862562
gene id: 30608:LOC105862562
uniprot id: A0A8B7F8T4
uniprot id: A0A8C5W3W7
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

30608:MRPL34
gene id: 30608:MRPL34
uniprot id: A0A8B7FQ58
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

30608:ALDH9A1
gene id: 30608:ALDH9A1
uniprot id: A0A8C5UUQ6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

30608:MPHOSPH8
gene id: 30608:MPHOSPH8
uniprot id: A0A8B7HBB5
uniprot id: A0A8B7HBB7
uniprot id: A0A8B7HBB8
names: Subcellular Location Annotation
messages: Nucleus

30608:TRAPPC4
gene id: 30608:TRAPPC4
uniprot id: A0A8C5Y3H4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

30608:NKIRAS2
gene id: 30608:NKIRAS2
uniprot id: A0A8B7GFL2
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

30608:LOC105860322
gene id: 30608:LOC105860322
uniprot id: A0A8B7EY90
names: Similarity
messages: Belongs to the folate receptor family.

30608:KIFC1
gene id: 30608:KIFC1
uniprot id: A0A8B7X481
uniprot id: A0A8B7X4S0
uniprot id: A0A8B7X5X9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:PATL2
gene id: 30608:PATL2
uniprot id: A0A8B7GH77
uniprot id: A0A8B7GH83
uniprot id: A0A8B7GHM0
uniprot id: A0A8B7X1K7
uniprot id: A0A8B7X1M9
uniprot id: A0A8B7X2U9
uniprot id: A0A8B7X3D1
names: Similarity
messages: Belongs to the PAT1 family.

30608:PSMA7
gene id: 30608:PSMA7
uniprot id: A0A8C5V207
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

30608:LOC105863165
gene id: 30608:LOC105863165
uniprot id: A0A8B7FBY5
names: Subcellular Location Annotation
messages: Membrane

30608:ALG14
gene id: 30608:ALG14
uniprot id: A0A8B7I6B7
uniprot id: A0A8C5VGL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG14 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane

30608:IDNK
gene id: 30608:IDNK
uniprot id: A0A8B7HE81
uniprot id: A0A8C5UPG2
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

30608:ITGAE
gene id: 30608:ITGAE
uniprot id: A0A8B7WMA0
uniprot id: A0A8B7WMD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

30608:LOC105858296
gene id: 30608:LOC105858296
uniprot id: A0A8C5XZE5
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:MAPK3
gene id: 30608:MAPK3
uniprot id: A0A8B7GBK0
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
messages: caveola
messages: focal adhesion

30608:PPP1R12A
gene id: 30608:PPP1R12A
uniprot id: A0A8B7FC81
uniprot id: A0A8B7FC85
uniprot id: A0A8B7FC90
uniprot id: A0A8B7FC93
uniprot id: A0A8B7FC96
uniprot id: A0A8B7FCE5
uniprot id: A0A8B7FCF0
uniprot id: A0A8B7FCF4
uniprot id: A0A8B7FCY9
uniprot id: A0A8B7FCZ4
uniprot id: A0A8C5XLI0
names: Subcellular Location Annotation
names: Subunit
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.
messages: stress fiber

30608:METTL14
gene id: 30608:METTL14
uniprot id: A0A8B7WXE8
uniprot id: A0A8B7WY85
uniprot id: A0A8C5V791
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MT-A70-like family.
messages: Heterodimer; heterodimerizes with METTL3 to form an antiparallel heterodimer that constitutes an active methyltransferase.
messages: Nucleus
messages: The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N(6) position of some mRNAs and regulates the circadian clock, differentiation of embryonic stem cells and cortical neurogenesis. In the heterodimer formed with METTL3, METTL14 constitutes the RNA-binding scaffold that recognizes the substrate rather than the catalytic core. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in mRNA stability and processing. M6A acts as a key regulator of mRNA stability by promoting mRNA destabilization and degradation. In embryonic stem cells (ESCs), m6A methylation of mRNAs encoding key naive pluripotency-promoting transcripts results in transcript destabilization. M6A regulates spermatogonial differentiation and meiosis and is essential for male fertility and spermatogenesis. M6A also regulates cortical neurogenesis: m6A methylation of transcripts related to transcription factors, neural stem cells, the cell cycle and neuronal differentiation during brain development promotes their destabilization and decay, promoting differentiation of radial glial cells.

30608:LOC105856606
gene id: 30608:LOC105856606
uniprot id: A0A8B7EI57
uniprot id: A0A8B7XE03
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

30608:C17H16orf72
gene id: 30608:C17H16orf72
uniprot id: A0A8B7HRV2
uniprot id: A0A8B7HU64
names: Subcellular Location Annotation
messages: Nucleus

30608:MICAL2
gene id: 30608:MICAL2
uniprot id: A0A8B7EWK7
uniprot id: A0A8B7X365
uniprot id: A0A8B7X370
uniprot id: A0A8B7X371
uniprot id: A0A8B7X376
uniprot id: A0A8B7X3Q4
uniprot id: A0A8B7X3Q9
uniprot id: A0A8B7X4N0
uniprot id: A0A8B7X4N7
uniprot id: A0A8B7X4X2
uniprot id: A0A8C5UP02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

30608:OLFML1
gene id: 30608:OLFML1
uniprot id: A0A8B7EWG6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:GLS2
gene id: 30608:GLS2
uniprot id: A0A8B7FLI4
uniprot id: A0A8B7FLK1
uniprot id: A0A8B7X7W6
names: Similarity
messages: Belongs to the glutaminase family.

30608:LOC105858291
gene id: 30608:LOC105858291
uniprot id: A0A8B7EP58
uniprot id: A0A8B7EPB0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:FAM126B
gene id: 30608:FAM126B
uniprot id: A0A8B7EIL9
uniprot id: A0A8B7EIM4
uniprot id: A0A8B7EIM6
uniprot id: A0A8C5VE04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Hyccin family.
messages: Cell membrane
messages: Membrane
messages: cytosol

30608:LOC105857155
gene id: 30608:LOC105857155
uniprot id: A0A8B7EJD7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

30608:TLR6
gene id: 30608:TLR6
uniprot id: A0A8B7FLE3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:PRKAR1B
gene id: 30608:PRKAR1B
uniprot id: A0A8B7FZK5
uniprot id: A0A8C5V6F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

30608:LOC105856095
gene id: 30608:LOC105856095
uniprot id: A0A8B7EHG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP8 subfamily.
messages: Chromosome
messages: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.
messages: Nucleus
messages: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
messages: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

30608:LOC105856981
gene id: 30608:LOC105856981
uniprot id: A0A8B7EJ32
uniprot id: A0A8C5UY82
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

30608:DOCK5
gene id: 30608:DOCK5
uniprot id: A0A8B7HM47
names: Similarity
messages: Belongs to the DOCK family.

30608:NDST2
gene id: 30608:NDST2
uniprot id: A0A8B7G0V1
uniprot id: A0A8B7WN96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

30608:CDH6
gene id: 30608:CDH6
uniprot id: A0A8B7XCU5
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

30608:GJA8
gene id: 30608:GJA8
uniprot id: A0A8B7G6I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

30608:ERC2
gene id: 30608:ERC2
uniprot id: A0A8B7FIR8
uniprot id: A0A8B7FIS7
uniprot id: A0A8B7FIS8
uniprot id: A0A8B7FIT2
uniprot id: A0A8B7FIW0
uniprot id: A0A8B7FIW7
uniprot id: A0A8B7FIZ9
uniprot id: A0A8B7FJ04
uniprot id: A0A8B7FJ08
uniprot id: A0A8B7FK68
uniprot id: A0A8B7WL31
names: Subcellular Location Annotation
messages: Cytoplasm

30608:LOC105858295
gene id: 30608:LOC105858295
uniprot id: A0A8C5XZE5
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:UNC5D
gene id: 30608:UNC5D
uniprot id: A0A8B7G7R8
uniprot id: A0A8B7G7S1
uniprot id: A0A8B7G7Y7
uniprot id: A0A8B7G8G1
uniprot id: A0A8B7G8W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

30608:LOC105885295
gene id: 30608:LOC105885295
uniprot id: A0A8B7I441
uniprot id: A0A8B7I445
uniprot id: A0A8B7I461
uniprot id: A0A8B7I466
uniprot id: A0A8B7I664
uniprot id: A0A8B7I774
uniprot id: A0A8B7WPP3
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105856393
gene id: 30608:LOC105856393
uniprot id: A0A8B7EG85
names: Similarity
messages: Belongs to the SSX family.

30608:PNPO
gene id: 30608:PNPO
uniprot id: A0A8B7GFW8
uniprot id: A0A8C5VGJ2
names: Function
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).

30608:DRAXIN
gene id: 30608:DRAXIN
uniprot id: A0A8C5ULY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the draxin family.
messages: Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
messages: Interacts with LRP6.
messages: Secreted

30608:ASZ1
gene id: 30608:ASZ1
uniprot id: Q2QL84
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with DDX4, PIWIL1, RANBP9 and TDRD1.
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation (By similarity).

30608:BYSL
gene id: 30608:BYSL
uniprot id: A0A8B7GYF9
names: Similarity
messages: Belongs to the bystin family.

30608:ATRX
gene id: 30608:ATRX
uniprot id: A0A8B7FPI0
uniprot id: A0A8B7FPI6
uniprot id: A0A8B7FPR3
uniprot id: A0A8B7FPS1
uniprot id: A0A8B7FQ20
uniprot id: A0A8B7FQT0
uniprot id: A0A8B7WZL1
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

30608:CAPN3
gene id: 30608:CAPN3
uniprot id: A0A8B7GGS1
uniprot id: A0A8B7GGS7
uniprot id: A0A8B7GGT2
uniprot id: A0A8B7GGT7
uniprot id: A0A8B7GH75
uniprot id: A0A8B7GHH4
uniprot id: A0A8B7GHH7
uniprot id: A0A8B7GHM4
uniprot id: A0A8B7GHM9
uniprot id: A0A8C5WA21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C2 family.
messages: Calcium-regulated non-lysosomal thiol-protease.
messages: Cytoplasm
messages: Homodimer.
messages: nucleolus

30608:FIBIN
gene id: 30608:FIBIN
uniprot id: A0A8B7EXL1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FIBIN family.
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer; disulfide-linked. Seems to also exist as monomers.
messages: Secreted

30608:MAGI3
gene id: 30608:MAGI3
uniprot id: A0A8B7HAY1
uniprot id: A0A8B7HAY5
uniprot id: A0A8C5XSL7
names: Subcellular Location Annotation
messages: Membrane

30608:GLYR1
gene id: 30608:GLYR1
uniprot id: A0A8B7EV68
uniprot id: A0A8B7EX61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIBADH-related family. NP60 subfamily.
messages: Chromosome

30608:LOC105881691
gene id: 30608:LOC105881691
uniprot id: A0A8B7HMQ9
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

30608:ITGA1
gene id: 30608:ITGA1
uniprot id: A0A8B7EP77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

30608:LOC105858336
gene id: 30608:LOC105858336
uniprot id: A0A8C5UXD5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:LOC105859574
gene id: 30608:LOC105859574
uniprot id: A0A8B7EUH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NFKB2
gene id: 30608:NFKB2
uniprot id: A0A8B7GQ05
uniprot id: A0A8B7GQB1
uniprot id: A0A8C5W364
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:IL13RA2
gene id: 30608:IL13RA2
uniprot id: A0A8B7FAU0
uniprot id: A0A8B7WZ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 5 subfamily.
messages: Membrane

30608:CSNK2A2
gene id: 30608:CSNK2A2
uniprot id: A0A8C5XFP4
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:GTF2B
gene id: 30608:GTF2B
uniprot id: A0A8B7F9J7
uniprot id: A0A8B7F9N0
uniprot id: A0A8B7FA05
names: Similarity
messages: Belongs to the TFIIB family.

30608:TSC22D2
gene id: 30608:TSC22D2
uniprot id: A0A8B7HL71
uniprot id: A0A8B7HL75
uniprot id: A0A8B7HMH0
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

30608:LOC105882830
gene id: 30608:LOC105882830
uniprot id: A0A8B7HUM2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

30608:MBOAT7
gene id: 30608:MBOAT7
uniprot id: A0A8B7GSH4
uniprot id: A0A8B7GSR3
names: Subcellular Location Annotation
messages: Membrane

30608:TRPM6
gene id: 30608:TRPM6
uniprot id: A0A8B7G036
uniprot id: A0A8B7G054
uniprot id: A0A8B7G068
uniprot id: A0A8B7G117
uniprot id: A0A8B7XAV4
uniprot id: A0A8B7XAV6
names: Similarity
names: Subcellular Location Annotation
messages: In the C-terminal section; belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.
messages: Membrane

30608:DLX1
gene id: 30608:DLX1
uniprot id: A0A8B7HJ53
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105877498
gene id: 30608:LOC105877498
uniprot id: A0A8B7H548
uniprot id: A0A8B7H554
names: Similarity
messages: Belongs to the amidase family.

30608:UGP2
gene id: 30608:UGP2
uniprot id: A0A8B7GD65
uniprot id: A0A8C5VKB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

30608:MRPL22
gene id: 30608:MRPL22
uniprot id: A0A8B7FPW8
uniprot id: A0A8B7FQ30
uniprot id: A0A8B7FQF1
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

30608:HESX1
gene id: 30608:HESX1
uniprot id: A0A8C5Y950
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANF homeobox family.
messages: Nucleus

30608:LOC105866564
gene id: 30608:LOC105866564
uniprot id: A0A8B7FR01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family. GTP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for GTP.
messages: Mitochondrion

30608:F13A1
gene id: 30608:F13A1
uniprot id: A0A8B7EFT0
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

30608:CTSD
gene id: 30608:CTSD
uniprot id: A0A8B7EVX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Lysosome
messages: extracellular space

30608:LOC105865881
gene id: 30608:LOC105865881
uniprot id: A0A8B7FNL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Odorant receptor.

30608:LOC105864576
gene id: 30608:LOC105864576
uniprot id: A0A8B7FHW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:HTR1B
gene id: 30608:HTR1B
uniprot id: A0A8B7I8N9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.
messages: Homodimer. Heterodimer with HTR1D.
messages: Ligands are bound in a hydrophobic pocket formed by the transmembrane helices.
messages: Membrane
messages: Palmitoylated.
messages: Phosphorylated.

30608:LOC105861608
gene id: 30608:LOC105861608
uniprot id: A0A8B7WN15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

30608:LOC105863105
gene id: 30608:LOC105863105
uniprot id: A0A8B7FB00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:GSDMD
gene id: 30608:GSDMD
uniprot id: A0A8B7FII5
uniprot id: A0A8C5XAY1
uniprot id: A0A8C5YC24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

30608:TFAP2A
gene id: 30608:TFAP2A
uniprot id: A0A8B7FKP0
uniprot id: A0A8C5VGM3
uniprot id: A0A8C5VNZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AP-2 family.
messages: Nucleus

30608:TBPL1
gene id: 30608:TBPL1
uniprot id: A0A8C5V5S9
names: Similarity
names: Subunit
messages: Belongs to the TBP family.
messages: Binds TFIIA and TFIIB.

30608:CEP170B
gene id: 30608:CEP170B
uniprot id: A0A8B7F248
uniprot id: A0A8B7F3M5
names: Similarity
messages: Belongs to the CEP170 family.

30608:IL17RB
gene id: 30608:IL17RB
uniprot id: A0A8B7GUI0
uniprot id: A0A8B7GUM5
uniprot id: A0A8B7GUP8
uniprot id: A0A8B7GWC1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:LOC105858736
gene id: 30608:LOC105858736
uniprot id: A0A8B7ER19
names: Subcellular Location Annotation
messages: Nucleus

30608:LTB4R2
gene id: 30608:LTB4R2
uniprot id: A0A8B7FRB0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:NFE2L2
gene id: 30608:NFE2L2
uniprot id: A0A8C5UVY1
uniprot id: A0A8C5VT82
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

30608:LOC105857570
gene id: 30608:LOC105857570
uniprot id: A0A8B7EMA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: centrosome

30608:SLC6A2
gene id: 30608:SLC6A2
uniprot id: A0A8B7FR56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

30608:DOT1L
gene id: 30608:DOT1L
uniprot id: A0A8B7F024
uniprot id: A0A8B7F028
uniprot id: A0A8B7F029
uniprot id: A0A8B7F037
uniprot id: A0A8B7F1U2
uniprot id: A0A8B7F2C9
uniprot id: A0A8C5V7V0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
messages: Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
messages: Histone methyltransferase. Methylates 'Lys-79' of histone H3.
messages: In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.
messages: Nucleus

30608:RIBC1
gene id: 30608:RIBC1
uniprot id: A0A8B7X179
names: Similarity
messages: Belongs to the RIB43A family.

30608:AFP
gene id: 30608:AFP
uniprot id: A0A8B7WWQ2
names: Subcellular Location Annotation
messages: Secreted

30608:LOC105874159
gene id: 30608:LOC105874159
uniprot id: A0A8C5Y8C4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

30608:SPAG11B
gene id: 30608:SPAG11B
uniprot id: A0A8B7G2T5
uniprot id: A0A8B7G2T7
uniprot id: A0A8B7G3N4
names: Subcellular Location Annotation
messages: Secreted

30608:FOXE1
gene id: 30608:FOXE1
uniprot id: A0A8B7GNV2
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105866821
gene id: 30608:LOC105866821
uniprot id: A0A8B7WND6
names: Similarity
messages: Belongs to the NLRP family.

30608:TFDP1
gene id: 30608:TFDP1
uniprot id: A0A8B7GEQ7
uniprot id: A0A8B7GF41
uniprot id: A0A8C5VFD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

30608:AKR1D1
gene id: 30608:AKR1D1
uniprot id: A0A8B7EUG5
names: Similarity
messages: Belongs to the aldo/keto reductase family.

30608:EFS
gene id: 30608:EFS
uniprot id: A0A8B7FHV1
names: Similarity
messages: Belongs to the CAS family.

30608:WASF3
gene id: 30608:WASF3
uniprot id: A0A8C5Y616
uniprot id: A0A8C6EGT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

30608:SERPINE3
gene id: 30608:SERPINE3
uniprot id: A0A8B7HKP3
names: Similarity
messages: Belongs to the serpin family.

30608:EFNB3
gene id: 30608:EFNB3
uniprot id: A0A8B7H7H4
uniprot id: A0A8C5XI11
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:DLX2
gene id: 30608:DLX2
uniprot id: A0A8B7HK13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

30608:SLBP
gene id: 30608:SLBP
uniprot id: A0A8B7HMD9
uniprot id: A0A8B7HME1
uniprot id: A0A8B7HME6
uniprot id: A0A8B7HNV4
uniprot id: A0A8B7HPV3
uniprot id: A0A8B7HPV8
uniprot id: A0A8C5Y1I8
uniprot id: A0A8C5Y3C0
names: Similarity
messages: Belongs to the FAM53 family.
messages: Belongs to the SLBP family.

30608:ITGA7
gene id: 30608:ITGA7
uniprot id: A0A8B7FJX3
uniprot id: A0A8B7FJY9
uniprot id: A0A8C5VC58
uniprot id: A0A8C5W894
uniprot id: A0A8C5Y377
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

30608:LIMK1
gene id: 30608:LIMK1
uniprot id: A0A8B7ERD2
uniprot id: A0A8B7ET47
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

30608:CAP2
gene id: 30608:CAP2
uniprot id: A0A8B7FKF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane
messages: Membrane

30608:STIM2
gene id: 30608:STIM2
uniprot id: A0A8B7GXL8
uniprot id: A0A8C5VE14
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:SSRP1
gene id: 30608:SSRP1
uniprot id: A0A8B7FB89
uniprot id: A0A8B7FBU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Nucleus

30608:NRG1
gene id: 30608:NRG1
uniprot id: A0A8B7H4D6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuregulin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

30608:SYNDIG1
gene id: 30608:SYNDIG1
uniprot id: A0A8B7F1J3
names: Similarity
messages: Belongs to the CD225/Dispanin family.

30608:INCENP
gene id: 30608:INCENP
uniprot id: A0A8C5USC3
uniprot id: A0A8C5VJX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INCENP family.
messages: Midbody
messages: Nucleus
messages: kinetochore
messages: spindle

30608:LOC105883499
gene id: 30608:LOC105883499
uniprot id: A0A8B7HVF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:BRINP1
gene id: 30608:BRINP1
uniprot id: A0A8C5UNK7
names: Similarity
messages: Belongs to the BRINP family.

30608:GAST
gene id: 30608:GAST
uniprot id: A0A8B7GFA4
uniprot id: A0A8C5UYU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.
messages: Secreted

30608:CCNO
gene id: 30608:CCNO
uniprot id: A0A8C5V3T7
names: Similarity
messages: Belongs to the cyclin family.

30608:ADGRB2
gene id: 30608:ADGRB2
uniprot id: A0A8B7GDZ2
uniprot id: A0A8B7GDZ3
uniprot id: A0A8B7GDZ7
uniprot id: A0A8B7GDZ8
uniprot id: A0A8B7GEH4
uniprot id: A0A8B7GEH9
uniprot id: A0A8B7GEQ1
uniprot id: A0A8B7GEQ6
uniprot id: A0A8B7GER1
uniprot id: A0A8B7GEV5
uniprot id: A0A8B7GEW0
uniprot id: A0A8B7GEW5
uniprot id: A0A8B7XCX9
uniprot id: A0A8B7XEN7
names: Subcellular Location Annotation
messages: Membrane

30608:TBL1XR1
gene id: 30608:TBL1XR1
uniprot id: A0A8B7FJ29
uniprot id: A0A8B7X2J9
uniprot id: A0A8B7X336
names: Similarity
messages: Belongs to the WD repeat EBI family.

30608:MYO1D
gene id: 30608:MYO1D
uniprot id: A0A8B7WN97
uniprot id: A0A8B7WNA4
uniprot id: A0A8C5V0N5
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:FADD
gene id: 30608:FADD
uniprot id: A0A8C5Y0E5
names: Function
messages: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.

30608:UBE2D2
gene id: 30608:UBE2D2
uniprot id: A0A8B7WR13
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:LOC105884147
gene id: 30608:LOC105884147
uniprot id: A0A8B7HYJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105869854
gene id: 30608:LOC105869854
uniprot id: A0A8B7G5C5
names: Subcellular Location Annotation
messages: Membrane

30608:DLX4
gene id: 30608:DLX4
uniprot id: A0A8B7I5Z8
names: Subcellular Location Annotation
messages: Nucleus

30608:RSPO1
gene id: 30608:RSPO1
uniprot id: A0A8C5VPX4
names: Similarity
messages: Belongs to the R-spondin family.

30608:LOC105883498
gene id: 30608:LOC105883498
uniprot id: A0A8B7HVH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105868562
gene id: 30608:LOC105868562
uniprot id: A0A8B7FZN6
names: Similarity
messages: Belongs to the TEX13 family.

30608:ZNF592
gene id: 30608:ZNF592
uniprot id: A0A8B7G8N9
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

30608:DES
gene id: 30608:DES
uniprot id: A0A8C5VD24
names: Similarity
messages: Belongs to the intermediate filament family.

30608:GBA2
gene id: 30608:GBA2
uniprot id: A0A8B7GQW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the non-lysosomal glucosylceramidase family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.

30608:KAT6B
gene id: 30608:KAT6B
uniprot id: A0A8B7G0E6
uniprot id: A0A8B7G0F2
uniprot id: A0A8B7G0H2
uniprot id: A0A8B7G0H7
uniprot id: A0A8B7G0I7
uniprot id: A0A8B7G1S1
uniprot id: A0A8B7G1S6
uniprot id: A0A8B7WM87
uniprot id: A0A8B7WNA1
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

30608:LOC105884174
gene id: 30608:LOC105884174
uniprot id: A0A8B7HYM5
names: Similarity
messages: Belongs to the histone H2B family.

30608:ATP8B3
gene id: 30608:ATP8B3
uniprot id: A0A8B7F0I0
uniprot id: A0A8B7F0I3
uniprot id: A0A8B7F286
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

30608:MTFR1
gene id: 30608:MTFR1
uniprot id: A0A8B7EDX8
uniprot id: A0A8B7EEI4
uniprot id: A0A8B7EGI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

30608:TEX261
gene id: 30608:TEX261
uniprot id: A0A8C5XFC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

30608:TMBIM4
gene id: 30608:TMBIM4
uniprot id: A0A8B7HLE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

30608:KRTCAP2
gene id: 30608:KRTCAP2
uniprot id: A0A8B7GKE7
uniprot id: A0A8B7GKQ1
uniprot id: A0A8B7GL90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRTCAP2 family.
messages: Membrane

30608:HYAL2
gene id: 30608:HYAL2
uniprot id: A0A8C5XET6
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

30608:LOC105855129
gene id: 30608:LOC105855129
uniprot id: A0A8B7EAS7
uniprot id: A0A8B7EDF5
uniprot id: A0A8B7XCE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Binds DNA as a homodimer or as a heterodimer with JUN or ATF2/CREBP1.
messages: Binds to the cAMP response element and activates transcription.
messages: Nucleus

30608:SNTA1
gene id: 30608:SNTA1
uniprot id: A0A8C5Y1F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

30608:LOC105866701
gene id: 30608:LOC105866701
uniprot id: A0A8B7FRL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 85 family.
messages: cytosol

30608:LOC105883393
gene id: 30608:LOC105883393
uniprot id: A0A8B7HUZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PITPNM3
gene id: 30608:PITPNM3
uniprot id: A0A8B7HF95
uniprot id: A0A8B7WNS7
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

30608:DEFB124
gene id: 30608:DEFB124
uniprot id: A0A8B7WQD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

30608:LBP
gene id: 30608:LBP
uniprot id: A0A8B7FPA6
uniprot id: A0A8B7FPU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide.
messages: Secreted
messages: When bound to LPS, interacts (via C-terminus) with soluble and membrane-bound CD14.

30608:LOC105862888
gene id: 30608:LOC105862888
uniprot id: A0A8B7FAB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS26 family.
messages: Endosome

30608:LOC105864508
gene id: 30608:LOC105864508
uniprot id: A0A8B7FHF9
uniprot id: A0A8B7HTN0
uniprot id: A0A8B7HTN6
uniprot id: A0A8B7HTP0
uniprot id: A0A8B7HVP3
uniprot id: A0A8B7HVQ0
uniprot id: A0A8B7HVW5
uniprot id: A0A8B7WWR3
uniprot id: A0A8C5W0D6
uniprot id: A0A8C5XNC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

30608:LMOD1
gene id: 30608:LMOD1
uniprot id: A0A8B7EWY4
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

30608:SLC7A6OS
gene id: 30608:SLC7A6OS
uniprot id: A0A8B7ERS5
uniprot id: A0A8C5Y8I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IWR1/SLC7A6OS family.
messages: Cytoplasm
messages: Directs RNA polymerase II nuclear import.
messages: Nucleus

30608:CD79B
gene id: 30608:CD79B
uniprot id: A0A8C5VYI5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:RPL38
gene id: 30608:RPL38
uniprot id: A0A8B7HBH3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

30608:CDK5RAP3
gene id: 30608:CDK5RAP3
uniprot id: A0A8B7GFG0
uniprot id: A0A8B7GFX3
uniprot id: A0A8B7GG86
names: Similarity
messages: Belongs to the CDK5RAP3 family.

30608:GFOD2
gene id: 30608:GFOD2
uniprot id: A0A8B7ESB0
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

30608:NAP1L5
gene id: 30608:NAP1L5
uniprot id: A0A8B7H0E1
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

30608:BHLHB9
gene id: 30608:BHLHB9
uniprot id: A0A8B7I0T6
names: Similarity
messages: Belongs to the GPRASP family.

30608:CUZD1
gene id: 30608:CUZD1
uniprot id: A0A8B7HK93
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:CUL2
gene id: 30608:CUL2
uniprot id: A0A8B7GF97
names: Similarity
messages: Belongs to the cullin family.

30608:TLE1
gene id: 30608:TLE1
uniprot id: A0A8B7EBN2
uniprot id: A0A8B7EC17
uniprot id: A0A8B7ECB0
uniprot id: A0A8C5VEI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

30608:KHSRP
gene id: 30608:KHSRP
uniprot id: A0A8B7G4M1
uniprot id: A0A8B7G4P9
uniprot id: A0A8B7G5F1
uniprot id: A0A8B7G601
names: Subcellular Location Annotation
messages: Nucleus

30608:MEA1
gene id: 30608:MEA1
uniprot id: A0A8B7GY95
uniprot id: A0A8B7GY97
uniprot id: A0A8B7H063
names: Function
messages: May play an important role in spermatogenesis and/or testis development.

30608:HGH1
gene id: 30608:HGH1
uniprot id: A0A8B7G290
names: Similarity
messages: Belongs to the HGH1 family.

30608:POLRMT
gene id: 30608:POLRMT
uniprot id: A0A8C5V554
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

30608:BORA
gene id: 30608:BORA
uniprot id: A0A8B7H0I1
names: Similarity
messages: Belongs to the BORA family.

30608:LOC105875873
gene id: 30608:LOC105875873
uniprot id: A0A8B7GYJ2
uniprot id: A0A8B7GYL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

30608:NAGK
gene id: 30608:NAGK
uniprot id: A0A8B7FBS5
uniprot id: A0A8C5VZK4
uniprot id: A0A8C5Y536
names: Similarity
messages: Belongs to the eukaryotic-type N-acetylglucosamine kinase family.

30608:GIMAP6
gene id: 30608:GIMAP6
uniprot id: A0A8B7HU49
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

30608:NRXN3
gene id: 30608:NRXN3
uniprot id: A0A8B7FT21
uniprot id: A0A8B7FT26
uniprot id: A0A8B7FT33
uniprot id: A0A8B7FT37
uniprot id: A0A8B7FT39
uniprot id: A0A8B7FT42
uniprot id: A0A8B7FT44
uniprot id: A0A8B7FT47
uniprot id: A0A8B7FT51
uniprot id: A0A8B7FT55
uniprot id: A0A8B7FT68
uniprot id: A0A8B7FT73
uniprot id: A0A8B7FT79
uniprot id: A0A8B7FT85
uniprot id: A0A8B7FT90
uniprot id: A0A8B7FTT1
uniprot id: A0A8B7FTT6
uniprot id: A0A8B7FTU4
uniprot id: A0A8B7FTU9
uniprot id: A0A8B7FTV5
uniprot id: A0A8B7FU25
uniprot id: A0A8B7FU30
uniprot id: A0A8B7FU34
uniprot id: A0A8B7FU43
uniprot id: A0A8B7X1X4
uniprot id: A0A8B7X1X9
uniprot id: A0A8B7X1Y5
uniprot id: A0A8B7X2H9
uniprot id: A0A8B7X378
uniprot id: A0A8B7X3P1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Presynaptic cell membrane

30608:RPS19BP1
gene id: 30608:RPS19BP1
uniprot id: A0A8B7EQ62
uniprot id: A0A8B7X883
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AROS family.
messages: nucleolus

30608:TAAR1
gene id: 30608:TAAR1
uniprot id: A0A8B7ECS6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:FRK
gene id: 30608:FRK
uniprot id: A0A8B7FJC2
uniprot id: A0A8B7FKS0
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

30608:LOC105870100
gene id: 30608:LOC105870100
uniprot id: A0A8B7G6G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: axon
messages: dendrite

30608:KCNAB2
gene id: 30608:KCNAB2
uniprot id: A0A8B7I7L6
uniprot id: A0A8B7I7R7
uniprot id: A0A8B7I9M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: axon
messages: cytoskeleton
messages: synaptosome

30608:GRK7
gene id: 30608:GRK7
uniprot id: A0A8B7G6D1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

30608:CUTA
gene id: 30608:CUTA
uniprot id: A0A8B7I930
uniprot id: A0A8C5VZJ2
names: Similarity
names: Subunit
messages: Belongs to the CutA family.
messages: Homotrimer.

30608:POLR3H
gene id: 30608:POLR3H
uniprot id: A0A8B7EQ33
uniprot id: A0A8B7ERR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

30608:TRPV4
gene id: 30608:TRPV4
uniprot id: A0A8B7WTE5
uniprot id: A0A8B7WTK6
uniprot id: A0A8B7WUU5
names: Subcellular Location Annotation
messages: Membrane

30608:NANOGNB
gene id: 30608:NANOGNB
uniprot id: A0A8B7H8U1
uniprot id: A0A8B7H8U5
names: Subcellular Location Annotation
messages: Nucleus

30608:SSBP2
gene id: 30608:SSBP2
uniprot id: A0A8B7HPT1
uniprot id: A0A8B7HPT3
uniprot id: A0A8B7HPT5
uniprot id: A0A8B7HRJ0
names: Subcellular Location Annotation
messages: Nucleus

30608:PENK
gene id: 30608:PENK
uniprot id: A0A8B7H0H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Increases glutamate release in the striatum and decreases GABA concentration in the striatum.
messages: Neuropeptide that competes with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.
messages: Secreted
messages: chromaffin granule lumen

30608:MYOZ2
gene id: 30608:MYOZ2
uniprot id: A0A8B7HWV9
names: Similarity
messages: Belongs to the myozenin family.

30608:DIEXF
gene id: 30608:DIEXF
uniprot id: A0A8C5UJL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP25 family.
messages: nucleolus

30608:APLP2
gene id: 30608:APLP2
uniprot id: A0A8B7HMC5
uniprot id: A0A8B7HMC7
uniprot id: A0A8C5W1Q4
uniprot id: A0A8C5XMI4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:JRKL
gene id: 30608:JRKL
uniprot id: A0A8B7EVR9
names: Subcellular Location Annotation
messages: Nucleus

30608:FSCN2
gene id: 30608:FSCN2
uniprot id: A0A8B7I2I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

30608:LOC105878590
gene id: 30608:LOC105878590
uniprot id: A0A8C5W3T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCC3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex. Thereby, plays an important role in ATP production by mitochondria. Cardiolipin-binding protein, it may also control the cardiolipin composition of mitochondria membranes and their morphology.

30608:ANXA2
gene id: 30608:ANXA2
uniprot id: A0A8B7HMV6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Membrane
messages: basement membrane

30608:TFEB
gene id: 30608:TFEB
uniprot id: A0A8C5VXL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

30608:LOC105862414
gene id: 30608:LOC105862414
uniprot id: A0A8B7F8J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CPA4
gene id: 30608:CPA4
uniprot id: A0A8C5UVU5
uniprot id: A0A8C6EHM3
names: Similarity
messages: Belongs to the peptidase M14 family.

30608:LOC105857711
gene id: 30608:LOC105857711
uniprot id: A0A8B7EM01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:DHRS7
gene id: 30608:DHRS7
uniprot id: A0A8B7HV22
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:PIAS1
gene id: 30608:PIAS1
uniprot id: A0A8B7GLD8
names: Similarity
messages: Belongs to the PIAS family.

30608:B3GNT7
gene id: 30608:B3GNT7
uniprot id: A0A8B7G2V1
uniprot id: A0A8B7G3P8
uniprot id: A0A8C6EL26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:LOC105883493
gene id: 30608:LOC105883493
uniprot id: A0A8B7HXK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TYMS
gene id: 30608:TYMS
uniprot id: A0A8B7WSL2
names: Similarity
messages: Belongs to the thymidylate synthase family.

30608:LOC105884114
gene id: 30608:LOC105884114
uniprot id: A0A8B7HYG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:HYLS1
gene id: 30608:HYLS1
uniprot id: A0A8B7X5I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HYLS1 family.
messages: centriole
messages: cilium

30608:MCMBP
gene id: 30608:MCMBP
uniprot id: A0A8B7EIZ0
uniprot id: A0A8B7EK33
uniprot id: A0A8B7ELC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCMBP family.
messages: Nucleus

30608:SELENBP1
gene id: 30608:SELENBP1
uniprot id: A0A8C5XLX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the selenium-binding protein family.
messages: Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
messages: Interacts with USP33.
messages: Membrane
messages: Nucleus
messages: cytosol

30608:GPR1
gene id: 30608:GPR1
uniprot id: A0A8B7EKN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

30608:SLC16A7
gene id: 30608:SLC16A7
uniprot id: A0A8B7HAE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

30608:ADGRG2
gene id: 30608:ADGRG2
uniprot id: A0A8B7HQJ8
uniprot id: A0A8B7HQK0
uniprot id: A0A8B7HQK5
uniprot id: A0A8B7HSD2
uniprot id: A0A8B7HSY4
names: Subcellular Location Annotation
messages: Membrane

30608:HACD1
gene id: 30608:HACD1
uniprot id: A0A8C5W369
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:GABBR2
gene id: 30608:GABBR2
uniprot id: A0A8B7GN13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

30608:ROM1
gene id: 30608:ROM1
uniprot id: A0A8B7HAF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRPH2/ROM1 family.
messages: Membrane

30608:RPL36
gene id: 30608:RPL36
uniprot id: A0A8C5W5J2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

30608:MMP17
gene id: 30608:MMP17
uniprot id: A0A8B7HE01
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

30608:STX6
gene id: 30608:STX6
uniprot id: A0A8B7EA86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Golgi apparatus membrane

30608:GDF3
gene id: 30608:GDF3
uniprot id: A0A8B7H8T9
names: Similarity
messages: Belongs to the TGF-beta family.

30608:STRADA
gene id: 30608:STRADA
uniprot id: A0A8B7F4V9
uniprot id: A0A8B7F4X4
uniprot id: A0A8B7F4Y1
uniprot id: A0A8C5VUM0
uniprot id: A0A8C5XMA5
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

30608:LOC105868492
gene id: 30608:LOC105868492
uniprot id: A0A8B7FZC3
uniprot id: A0A8B7G0A0
names: Similarity
messages: Belongs to the YY transcription factor family.

30608:CDC42BPB
gene id: 30608:CDC42BPB
uniprot id: A0A8B7F1T2
uniprot id: A0A8B7F1T4
uniprot id: A0A8B7F1T6
uniprot id: A0A8B7F3S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: Cytoplasm
messages: lamellipodium

30608:LOC105868338
gene id: 30608:LOC105868338
uniprot id: A0A8B7FZB0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.

30608:SLC4A10
gene id: 30608:SLC4A10
uniprot id: A0A8B7EAA1
uniprot id: A0A8B7EAD2
uniprot id: A0A8B7EAJ2
uniprot id: A0A8B7EAJ8
uniprot id: A0A8B7EAZ2
uniprot id: A0A8B7ED07
uniprot id: A0A8B7ED12
uniprot id: A0A8B7X9B1
uniprot id: A0A8B7XAL7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lateral cell membrane
messages: Membrane

30608:GPR50
gene id: 30608:GPR50
uniprot id: A0A8B7EB17
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:SIDT2
gene id: 30608:SIDT2
uniprot id: A0A8B7GZG7
uniprot id: A0A8B7GZG9
uniprot id: A0A8B7GZH0
uniprot id: A0A8B7H1D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SID1 family.
messages: Membrane

30608:GPN3
gene id: 30608:GPN3
uniprot id: A0A8B7WTC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

30608:TRMT1L
gene id: 30608:TRMT1L
uniprot id: A0A8B7EEE3
uniprot id: A0A8C5VC02
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: May play a role in motor coordination and exploratory behavior.

30608:GUF1
gene id: 30608:GUF1
uniprot id: A0A8B7WWP2
uniprot id: A0A8C5Y4R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

30608:RRM2B
gene id: 30608:RRM2B
uniprot id: A0A8C5XM79
names: Cofactor
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.

30608:LOC105870656
gene id: 30608:LOC105870656
uniprot id: A0A8B7XE78
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:TBX22
gene id: 30608:TBX22
uniprot id: A0A8B7FQ35
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

30608:ADRB1
gene id: 30608:ADRB1
uniprot id: A0A8B7GY69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ADGRF5
gene id: 30608:ADGRF5
uniprot id: A0A8B7EXZ6
uniprot id: A0A8B7EY03
uniprot id: A0A8B7EZU7
uniprot id: A0A8B7F035
uniprot id: A0A8B7X4C0
uniprot id: A0A8C5W1G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

30608:CLRN3
gene id: 30608:CLRN3
uniprot id: A0A8B7HHX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

30608:IRF7
gene id: 30608:IRF7
uniprot id: A0A8B7GP86
uniprot id: A0A8B7GPI8
uniprot id: A0A8B7GPP2
uniprot id: A0A8B7GQQ3
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105860377
gene id: 30608:LOC105860377
uniprot id: A0A8C5VX90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SYNE1
gene id: 30608:SYNE1
uniprot id: A0A8B7X534
uniprot id: A0A8B7X539
uniprot id: A0A8B7X540
uniprot id: A0A8B7X5P1
uniprot id: A0A8B7X6U3
uniprot id: A0A8B7X6U8
uniprot id: A0A8B7X702
uniprot id: A0A8B7X708
names: Similarity
messages: Belongs to the nesprin family.

30608:NRTN
gene id: 30608:NRTN
uniprot id: A0A8B7G4J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

30608:ELOVL5
gene id: 30608:ELOVL5
uniprot id: A0A8B7HGG3
uniprot id: A0A8B7HH85
uniprot id: A0A8B7HJ46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Belongs to the ELO family. ELOVL5 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: dendrite

30608:TATDN1
gene id: 30608:TATDN1
uniprot id: A0A8B7HZF0
uniprot id: A0A8B7I1J0
uniprot id: A0A8B7XA12
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

30608:FLCN
gene id: 30608:FLCN
uniprot id: A0A8B7WMV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the folliculin family.
messages: Lysosome membrane
messages: Membrane
messages: Nucleus
messages: centrosome
messages: cilium
messages: cytosol
messages: spindle

30608:OPN3
gene id: 30608:OPN3
uniprot id: A0A8C5UV69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

30608:LOC105857926
gene id: 30608:LOC105857926
uniprot id: A0A8B7EMM5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:MAP4
gene id: 30608:MAP4
uniprot id: A0A8B7GT61
uniprot id: A0A8B7GT64
uniprot id: A0A8B7GT68
uniprot id: A0A8B7GT70
uniprot id: A0A8B7GT73
uniprot id: A0A8B7GT77
uniprot id: A0A8B7GT78
uniprot id: A0A8B7GT82
uniprot id: A0A8B7GTC5
uniprot id: A0A8B7GTD2
uniprot id: A0A8B7GTD9
uniprot id: A0A8B7GTE4
uniprot id: A0A8B7GTE6
uniprot id: A0A8B7GTF2
uniprot id: A0A8B7GUX8
uniprot id: A0A8B7GUY5
uniprot id: A0A8B7GUZ0
uniprot id: A0A8B7WKZ1
names: Subcellular Location Annotation
messages: cytoskeleton

30608:LOC105875332
gene id: 30608:LOC105875332
uniprot id: A0A8B7GW31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ADAMTS20
gene id: 30608:ADAMTS20
uniprot id: A0A8B7F3J7
uniprot id: A0A8B7F3P0
uniprot id: A0A8B7X5Q9
uniprot id: A0A8B7X7H5
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:KCNK7
gene id: 30608:KCNK7
uniprot id: A0A8B7HA31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

30608:PRDM5
gene id: 30608:PRDM5
uniprot id: A0A8B7F0J5
uniprot id: A0A8B7F0K3
uniprot id: A0A8B7F2A8
uniprot id: A0A8B7F2W4
names: Subcellular Location Annotation
messages: Nucleus

30608:TBCA
gene id: 30608:TBCA
uniprot id: A0A8C5Y8X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
messages: cytoskeleton

30608:PDCL
gene id: 30608:PDCL
uniprot id: A0A8B7GV06
names: Similarity
messages: Belongs to the phosducin family.

30608:LOC105860018
gene id: 30608:LOC105860018
uniprot id: A0A8C5V637
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

30608:CHIA
gene id: 30608:CHIA
uniprot id: A0A8B7FFK8
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

30608:NUDT3
gene id: 30608:NUDT3
uniprot id: A0A8C5VJD1
names: Similarity
messages: Belongs to the Nudix hydrolase family. DIPP subfamily.

30608:GSC
gene id: 30608:GSC
uniprot id: A0A8C5Y7K2
names: Subcellular Location Annotation
messages: Nucleus

30608:KRT19
gene id: 30608:KRT19
uniprot id: A0A8C5W268
names: Similarity
messages: Belongs to the intermediate filament family.

30608:PPEF1
gene id: 30608:PPEF1
uniprot id: A0A8B7HQK3
uniprot id: A0A8B7HSE5
uniprot id: A0A8B7HSZ3
names: Similarity
messages: Belongs to the PPP phosphatase family.

30608:AFG3L2
gene id: 30608:AFG3L2
uniprot id: A0A8B7F1C6
uniprot id: A0A8B7F1D0
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

30608:NR2E1
gene id: 30608:NR2E1
uniprot id: A0A8B7FJH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

30608:LOC105859845
gene id: 30608:LOC105859845
uniprot id: A0A8B7EW18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I) and RNA polymerase III (Pol III) complexes consisting of at least 13 and 17 subunits, respectively.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively.

30608:LOC105867901
gene id: 30608:LOC105867901
uniprot id: A0A8B7FWR1
names: Subcellular Location Annotation
messages: Membrane

30608:PLOD1
gene id: 30608:PLOD1
uniprot id: A0A8C5UU80
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

30608:LCORL
gene id: 30608:LCORL
uniprot id: A0A8B7EFE5
uniprot id: A0A8B7EH80
names: Subcellular Location Annotation
messages: Nucleus

30608:STON2
gene id: 30608:STON2
uniprot id: A0A8B7FWJ6
uniprot id: A0A8B7FXI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Stoned B family.
messages: Cytoplasm

30608:NAB1
gene id: 30608:NAB1
uniprot id: A0A8B7H754
uniprot id: A0A8B7H755
uniprot id: A0A8B7H777
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

30608:GPBP1
gene id: 30608:GPBP1
uniprot id: A0A8B7H453
uniprot id: A0A8C5VBI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

30608:INSIG2
gene id: 30608:INSIG2
uniprot id: A0A8B7H433
uniprot id: A0A8B7XAP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

30608:PDGFB
gene id: 30608:PDGFB
uniprot id: A0A8B7EQR4
uniprot id: A0A8B7ESE2
uniprot id: A0A8B7ESS5
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

30608:FABP9
gene id: 30608:FABP9
uniprot id: A0A8B7ENC5
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

30608:ADAMDEC1
gene id: 30608:ADAMDEC1
uniprot id: A0A8C5XW45
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:CHST1
gene id: 30608:CHST1
uniprot id: A0A8B7I4E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

30608:LOC105858220
gene id: 30608:LOC105858220
uniprot id: A0A8B7EP24
names: Similarity
messages: Belongs to the aldo/keto reductase family.

30608:PPP1R3B
gene id: 30608:PPP1R3B
uniprot id: A0A8B7ELW1
names: Subunit
messages: Interacts with glycogen, PPP1CC catalytic subunit of PP1 and PYGL. Associates with glycogen particles. Forms complexes with debranching enzyme, glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity.

30608:IRF2BP1
gene id: 30608:IRF2BP1
uniprot id: A0A8B7G4X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

30608:SF3B6
gene id: 30608:SF3B6
uniprot id: A0A8C5XLN6
names: Subcellular Location Annotation
messages: Nucleus

30608:PET117
gene id: 30608:PET117
uniprot id: A0A8B7HEZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PET117 family.
messages: Mitochondrion

30608:MTMR6
gene id: 30608:MTMR6
uniprot id: A0A8B7EFQ4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

30608:NFE2L3
gene id: 30608:NFE2L3
uniprot id: A0A8B7GYU0
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

30608:ME1
gene id: 30608:ME1
uniprot id: A0A8B7GNP9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

30608:LBH
gene id: 30608:LBH
uniprot id: A0A8B7HZT8
uniprot id: A0A8B7HZU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LBH family.
messages: Cytoplasm
messages: Nucleus
messages: Transcriptional activator.

30608:DNAJA4
gene id: 30608:DNAJA4
uniprot id: A0A8B7ELZ3
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105864643
gene id: 30608:LOC105864643
uniprot id: A0A8B7FHX2
uniprot id: A0A8B7FI10
uniprot id: A0A8B7X168
uniprot id: A0A8B7X1S0
uniprot id: A0A8B7X2Z8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M8 family.
messages: Binds 1 zinc ion per subunit.

30608:ATF7IP
gene id: 30608:ATF7IP
uniprot id: A0A8B7X621
uniprot id: A0A8B7X627
uniprot id: A0A8C5V9W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCAF family.
messages: Nucleus

30608:MINDY1
gene id: 30608:MINDY1
uniprot id: A0A8B7WW65
uniprot id: A0A8B7WWW2
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
messages: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.

30608:LOC105884615
gene id: 30608:LOC105884615
uniprot id: A0A8B7X831
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:B4GALT4
gene id: 30608:B4GALT4
uniprot id: A0A8B7HG25
uniprot id: A0A8B7HG54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

30608:DAZL
gene id: 30608:DAZL
uniprot id: A0A8B7GHW0
names: Subcellular Location Annotation
messages: Cytoplasm

30608:ADAM30
gene id: 30608:ADAM30
uniprot id: A0A8B7G566
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:CFAP36
gene id: 30608:CFAP36
uniprot id: A0A8B7H9C7
names: Similarity
messages: Belongs to the CFAP36 family.

30608:SLC39A9
gene id: 30608:SLC39A9
uniprot id: A0A8B7HHB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion
messages: Nucleus
messages: Transports zinc ions across cell and organelle membranes into the cytoplasm and regulates intracellular zinc homeostasis. Participates in the zinc ions efflux out of the secretory compartments. Also functions as membrane androgen receptor that mediates, through a G protein, the non-classical androgen signaling pathway, characterized by the activation of MAPK3/MAPK1 (Erk1/2) and transcription factors CREB1 or ATF1. Moreover, has dual functions as membrane-bound androgen receptor and as an androgen-dependent zinc transporter both of which are mediated through an inhibitory G protein (Gi) that mediates both MAP kinase and zinc signaling leading to the androgen-dependent apoptotic process.
messages: perinuclear region
messages: trans-Golgi network membrane

30608:FAM161B
gene id: 30608:FAM161B
uniprot id: A0A8B7EQ21
uniprot id: A0A8B7ERK9
uniprot id: A0A8C5VTC0
names: Similarity
messages: Belongs to the FAM161 family.

30608:GSS
gene id: 30608:GSS
uniprot id: A0A8B7FN93
uniprot id: A0A8C5W807
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

30608:TIGD5
gene id: 30608:TIGD5
uniprot id: A0A8B7FIR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tigger transposable element derived protein family.
messages: Nucleus

30608:SCAND1
gene id: 30608:SCAND1
uniprot id: A0A8B7FP87
names: Subcellular Location Annotation
messages: Nucleus

30608:CISD2
gene id: 30608:CISD2
uniprot id: A0A8C5XTK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CISD protein family. CISD2 subfamily.
messages: Binds 1 [2Fe-2S] cluster.
messages: Endoplasmic reticulum membrane
messages: Homodimer.
messages: Mitochondrion outer membrane
messages: Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy.

30608:POLD3
gene id: 30608:POLD3
uniprot id: A0A8B7EYM7
uniprot id: A0A8B7EYM8
uniprot id: A0A8B7EYN0
uniprot id: A0A8B7F0E6
uniprot id: A0A8B7F0F1
uniprot id: A0A8B7F0R5
uniprot id: A0A8B7F0S0
names: Subcellular Location Annotation
messages: Nucleus

30608:GPATCH11
gene id: 30608:GPATCH11
uniprot id: A0A8C5XXN8
names: Similarity
messages: Belongs to the GPATCH11 family.

30608:ERGIC1
gene id: 30608:ERGIC1
uniprot id: A0A8B7WWQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

30608:BLCAP
gene id: 30608:BLCAP
uniprot id: A0A8B7FNY9
names: Function
names: Similarity
messages: Belongs to the BLCAP family.
messages: May regulate cell proliferation and coordinate apoptosis and cell cycle progression via a novel mechanism independent of both p53/TP53 and NF-kappa-B.

30608:F13B
gene id: 30608:F13B
uniprot id: A0A8B7EWU8
uniprot id: A0A8B7EWU9
uniprot id: A0A8B7EYS3
uniprot id: A0A8B7EYV6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:GLB1
gene id: 30608:GLB1
uniprot id: A0A8C5YGM7
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

30608:LOC105879033
gene id: 30608:LOC105879033
uniprot id: A0A8B7HC79
names: Subcellular Location Annotation
messages: Nucleus

30608:KDM4C
gene id: 30608:KDM4C
uniprot id: A0A8B7EHG9
uniprot id: A0A8B7EHZ1
uniprot id: A0A8B7EI08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM3 histone demethylase family.
messages: Nucleus

30608:LOC105865222
gene id: 30608:LOC105865222
uniprot id: A0A8B7FKH8
uniprot id: A0A8B7X6Q7
uniprot id: A0A8B7X7T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.
messages: Forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex.
messages: Virion

30608:SRPX2
gene id: 30608:SRPX2
uniprot id: A0A8B7GJZ7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105883330
gene id: 30608:LOC105883330
uniprot id: A0A8B7HUS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:GJB7
gene id: 30608:GJB7
uniprot id: A0A8B7FE17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

30608:CITED1
gene id: 30608:CITED1
uniprot id: A0A8B7HPR8
uniprot id: A0A8B7HRH0
uniprot id: A0A8C5VL49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

30608:ZKSCAN7
gene id: 30608:ZKSCAN7
uniprot id: A0A8C5XKK0
names: Subcellular Location Annotation
messages: Nucleus

30608:CRYGS
gene id: 30608:CRYGS
uniprot id: A0A8B7I2Y9
uniprot id: A0A8B7I305
uniprot id: A0A8C5YHB2
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

30608:PTBP1
gene id: 30608:PTBP1
uniprot id: A0A8B7F057
uniprot id: A0A8B7F1X6
uniprot id: A0A8C5VGU7
names: Subcellular Location Annotation
messages: Nucleus

30608:METTL16
gene id: 30608:METTL16
uniprot id: A0A8B7EMX9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: RNA N6-methyltransferase that methylates adenosine residues at the N(6) position of a subset of RNAs and is involved in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6-methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure.

30608:LOC105883419
gene id: 30608:LOC105883419
uniprot id: A0A8B7HX85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ROCK1
gene id: 30608:ROCK1
uniprot id: A0A8B7F3K6
uniprot id: A0A8C5V5C3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by RHOA binding. Inhibited by Y-27632.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Homodimer.
messages: Membrane
messages: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.

30608:POLR2G
gene id: 30608:POLR2G
uniprot id: A0A8B7HAC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. RPB4 and RPB7 form a subcomplex that protrudes from the 10-subunit Pol II core complex.
messages: DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

30608:TRAM1
gene id: 30608:TRAM1
uniprot id: A0A8C5YD50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

30608:PIWIL2
gene id: 30608:PIWIL2
uniprot id: A0A8B7ELM4
names: Similarity
messages: Belongs to the argonaute family.

30608:GUCY1B3
gene id: 30608:GUCY1B3
uniprot id: A0A8B7HPH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

30608:LOC105875330
gene id: 30608:LOC105875330
uniprot id: A0A8B7GW64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MED28
gene id: 30608:MED28
uniprot id: A0A8C5V930
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 28 family.
messages: Nucleus

30608:LOC109729574
gene id: 30608:LOC109729574
uniprot id: A0A8B7WNV1
names: Similarity
messages: Belongs to the TMA7 family.

30608:CBX7
gene id: 30608:CBX7
uniprot id: A0A8B7EQQ5
uniprot id: A0A8B7X8G9
names: Subcellular Location Annotation
messages: Nucleus

30608:SNF8
gene id: 30608:SNF8
uniprot id: A0A8B7I520
uniprot id: A0A8C6EL57
names: Similarity
messages: Belongs to the SNF8 family.

30608:RRAD
gene id: 30608:RRAD
uniprot id: A0A8C5Y6W2
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

30608:PDC
gene id: 30608:PDC
uniprot id: A0A8B7EC65
names: Similarity
messages: Belongs to the phosducin family.

30608:IZUMO1
gene id: 30608:IZUMO1
uniprot id: A0A8B7FMB4
uniprot id: A0A8B7FMH3
uniprot id: A0A8B7FMK8
uniprot id: A0A8B7WUD6
uniprot id: A0A8B7WVT1
names: Similarity
messages: Belongs to the Izumo family.

30608:SNX4
gene id: 30608:SNX4
uniprot id: A0A8B7X641
names: Similarity
messages: Belongs to the sorting nexin family.

30608:WEE1
gene id: 30608:WEE1
uniprot id: A0A8C5W6Y7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

30608:ATP6V1B1
gene id: 30608:ATP6V1B1
uniprot id: A0A8B7FBR4
uniprot id: A0A8B7FBX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

30608:RPL7L1
gene id: 30608:RPL7L1
uniprot id: A0A8B7GYA0
uniprot id: A0A8B7GYC0
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

30608:LOC109730976
gene id: 30608:LOC109730976
uniprot id: A0A8B7X8V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

30608:ARMC8
gene id: 30608:ARMC8
uniprot id: A0A8B7HY84
uniprot id: A0A8B7HY94
uniprot id: A0A8C6ELI9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:RAB32
gene id: 30608:RAB32
uniprot id: A0A8C5UZZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

30608:CACTIN
gene id: 30608:CACTIN
uniprot id: A0A8B7GP31
names: Similarity
messages: Belongs to the CACTIN family.

30608:ZMPSTE24
gene id: 30608:ZMPSTE24
uniprot id: A0A8C5UJW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

30608:KALRN
gene id: 30608:KALRN
uniprot id: A0A8B7HFN7
uniprot id: A0A8B7HFN8
uniprot id: A0A8B7HFP5
uniprot id: A0A8B7HFP6
uniprot id: A0A8B7HFR2
uniprot id: A0A8B7HFS0
uniprot id: A0A8B7HGA2
uniprot id: A0A8B7HIC3
uniprot id: A0A8B7X4D9
uniprot id: A0A8B7X4E5
uniprot id: A0A8B7X4F5
uniprot id: A0A8B7X4F7
uniprot id: A0A8B7X4G0
uniprot id: A0A8B7X4G7
uniprot id: A0A8B7X4H2
uniprot id: A0A8B7X4J3
uniprot id: A0A8B7X500
uniprot id: A0A8B7X507
uniprot id: A0A8B7X648
uniprot id: A0A8B7X653
uniprot id: A0A8B7X657
uniprot id: A0A8B7X662
uniprot id: A0A8B7X682
uniprot id: A0A8B7X685
uniprot id: A0A8B7X690
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cytoplasm

30608:CELSR1
gene id: 30608:CELSR1
uniprot id: A0A8B7FTI4
uniprot id: A0A8B7FTI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor that may have an important role in cell/cell signaling during nervous system formation.

30608:RPL3
gene id: 30608:RPL3
uniprot id: A0A8C5XQ80
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

30608:TSPYL2
gene id: 30608:TSPYL2
uniprot id: A0A8B7F2H2
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

30608:NDUFB7
gene id: 30608:NDUFB7
uniprot id: A0A8B7FWT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

30608:VPS54
gene id: 30608:VPS54
uniprot id: A0A8B7X236
uniprot id: A0A8B7X3V1
uniprot id: A0A8C5YCZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS54 family.
messages: trans-Golgi network

30608:LOXHD1
gene id: 30608:LOXHD1
uniprot id: A0A8B7I6M0
uniprot id: A0A8B7I7Q4
uniprot id: A0A8C5UJS0
uniprot id: A0A8C5VUS9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:MALSU1
gene id: 30608:MALSU1
uniprot id: A0A8B7GYM1
names: Similarity
messages: Belongs to the Iojap/RsfS family.

30608:LOC105882228
gene id: 30608:LOC105882228
uniprot id: A0A8B7HRM7
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

30608:SFXN1
gene id: 30608:SFXN1
uniprot id: A0A8B7WWM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane

30608:CEP70
gene id: 30608:CEP70
uniprot id: A0A8B7F983
uniprot id: A0A8B7F987
uniprot id: A0A8B7F9Q8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Directly interacts with tubulin-gamma; this interaction determines centrosomal localization.
messages: Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle.
messages: centrosome

30608:OAZ3
gene id: 30608:OAZ3
uniprot id: A0A8B7GKM9
names: Similarity
messages: Belongs to the ODC antizyme family.

30608:LOC105860870
gene id: 30608:LOC105860870
uniprot id: A0A8B7F0Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

30608:LOC105865628
gene id: 30608:LOC105865628
uniprot id: A0A8B7FM76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CENPI
gene id: 30608:CENPI
uniprot id: A0A8C5VT20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-I/CTF3 family.
messages: Nucleus
messages: centromere

30608:MPP5
gene id: 30608:MPP5
uniprot id: A0A8B7HH93
uniprot id: A0A8B7X0U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Endomembrane system
messages: adherens junction
messages: tight junction

30608:LOC105883383
gene id: 30608:LOC105883383
uniprot id: A0A8B7HUY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:OAZ1
gene id: 30608:OAZ1
uniprot id: A0A8B7F023
names: Similarity
messages: Belongs to the ODC antizyme family.

30608:LRRC8B
gene id: 30608:LRRC8B
uniprot id: A0A8B7I7V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

30608:BCL2
gene id: 30608:BCL2
uniprot id: A0A8B7H1C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: Nucleus membrane

30608:LOC105858696
gene id: 30608:LOC105858696
uniprot id: A0A8C5Y8I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:TMEM56
gene id: 30608:TMEM56
uniprot id: A0A8B7I680
uniprot id: A0A8B7I690
uniprot id: A0A8B7I6D2
uniprot id: A0A8B7I874
uniprot id: A0A8B7I884
uniprot id: A0A8B7I9H9
names: Subcellular Location Annotation
messages: Membrane

30608:FNBP1
gene id: 30608:FNBP1
uniprot id: A0A8B7XBE0
uniprot id: A0A8B7XBE1
uniprot id: A0A8B7XBE3
uniprot id: A0A8B7XBE4
uniprot id: A0A8B7XBE5
uniprot id: A0A8B7XBE7
uniprot id: A0A8B7XBE8
uniprot id: A0A8B7XCA5
uniprot id: A0A8B7XCB0
uniprot id: A0A8B7XCB5
uniprot id: A0A8B7XCC0
uniprot id: A0A8B7XD42
uniprot id: A0A8B7XD47
uniprot id: A0A8B7XD51
uniprot id: A0A8B7XD56
uniprot id: A0A8B7XDM0
uniprot id: A0A8B7XDM3
uniprot id: A0A8B7XDM8
names: Subcellular Location Annotation
messages: cytoskeleton

30608:HOXC12
gene id: 30608:HOXC12
uniprot id: A0A8B7GAJ1
names: Subcellular Location Annotation
messages: Nucleus

30608:TMEM256
gene id: 30608:TMEM256
uniprot id: A0A8B7H906
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM256 family.
messages: Membrane

30608:GALNT4
gene id: 30608:GALNT4
uniprot id: A0A8B7FM95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

30608:LOC105882984
gene id: 30608:LOC105882984
uniprot id: A0A8B7WTV9
names: Function
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.
messages: Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA: forms a stable thiazolidine linkage between a ring-opened abasic site and the alpha-amino and sulfhydryl substituents of its N-terminal catalytic cysteine residue. The HMCES DNA-protein cross-link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endonucleases that are error-prone and would generate mutations and double-strand breaks. Has preference for ssDNA, but can also accommodate double-stranded DNA with 3' or 5' overhang (dsDNA), and dsDNA-ssDNA 3' junction.

30608:LOC105885149
gene id: 30608:LOC105885149
uniprot id: A0A8B7I5E7
names: Subcellular Location Annotation
messages: Membrane

30608:NAV2
gene id: 30608:NAV2
uniprot id: A0A8B7FST3
uniprot id: A0A8B7FSV1
uniprot id: A0A8B7FSV7
uniprot id: A0A8B7FSW2
uniprot id: A0A8B7FSW6
uniprot id: A0A8B7FSX1
uniprot id: A0A8B7FTG7
uniprot id: A0A8B7FTH5
uniprot id: A0A8B7FTI2
uniprot id: A0A8B7FTJ2
uniprot id: A0A8B7FTT0
uniprot id: A0A8B7FTT7
uniprot id: A0A8B7FTU3
uniprot id: A0A8B7FTV0
uniprot id: A0A8B7X350
uniprot id: A0A8C5VBS8
uniprot id: A0A8C5XTU5
names: Similarity
messages: Belongs to the Nav/unc-53 family.

30608:LOC105860332
gene id: 30608:LOC105860332
uniprot id: A0A8B7X3S8
names: Subcellular Location Annotation
messages: Membrane

30608:THADA
gene id: 30608:THADA
uniprot id: A0A8B7FS82
uniprot id: A0A8B7FT87
uniprot id: A0A8B7XAW2
names: Function
names: Similarity
messages: Belongs to the THADA family.
messages: Together with methyltransferase FTSJ1, methylates the 2'-O-ribose of nucleotides at position 32 of the anticodon loop of substrate tRNAs.

30608:LOC105870502
gene id: 30608:LOC105870502
uniprot id: A0A8B7G9B5
names: Subcellular Location Annotation
messages: Membrane

30608:CSMD2
gene id: 30608:CSMD2
uniprot id: A0A8B7GDM5
uniprot id: A0A8B7GDM8
uniprot id: A0A8B7GEJ1
uniprot id: A0A8B7XDI2
uniprot id: A0A8B7XDI3
uniprot id: A0A8B7XDK7
uniprot id: A0A8B7XEY0
uniprot id: A0A8B7XF96
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:NAA25
gene id: 30608:NAA25
uniprot id: A0A8B7WTG4
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

30608:HSD3B7
gene id: 30608:HSD3B7
uniprot id: A0A8C5WAN3
names: Similarity
messages: Belongs to the 3-beta-HSD family.

30608:PPP2R5E
gene id: 30608:PPP2R5E
uniprot id: A0A8B7H8Y6
uniprot id: A0A8C5VI98
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

30608:AMER3
gene id: 30608:AMER3
uniprot id: A0A8B7G3W6
names: Similarity
messages: Belongs to the Amer family.

30608:DISP3
gene id: 30608:DISP3
uniprot id: A0A8C5V0M0
names: Subcellular Location Annotation
messages: Membrane

30608:KCND1
gene id: 30608:KCND1
uniprot id: A0A8B7EGB0
uniprot id: A0A8B7EGQ7
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

30608:CALY
gene id: 30608:CALY
uniprot id: A0A8B7F449
names: Similarity
messages: Belongs to the NSG family.

30608:PSMD12
gene id: 30608:PSMD12
uniprot id: A0A8B7F4X5
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

30608:CMTM3
gene id: 30608:CMTM3
uniprot id: A0A8B7EU28
uniprot id: A0A8C5VD87
names: Subcellular Location Annotation
messages: Membrane

30608:MRPL9
gene id: 30608:MRPL9
uniprot id: A0A8B7GJH2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.

30608:DNAJC24
gene id: 30608:DNAJC24
uniprot id: A0A8B7HVK6
uniprot id: A0A8B7HVS1
uniprot id: A0A8C5UXL3
names: Similarity
messages: Belongs to the DPH4 family.

30608:SKAP2
gene id: 30608:SKAP2
uniprot id: A0A8B7H0M5
uniprot id: A0A8C5UP47
names: Similarity
messages: Belongs to the SKAP family.

30608:EPHB4
gene id: 30608:EPHB4
uniprot id: A0A8B7FYG8
names: Subcellular Location Annotation
messages: Membrane

30608:BROX
gene id: 30608:BROX
uniprot id: A0A8B7ECP4
names: Similarity
messages: Belongs to the BROX family.

30608:SYPL1
gene id: 30608:SYPL1
uniprot id: A0A8C5XIN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

30608:TAMM41
gene id: 30608:TAMM41
uniprot id: A0A8B7HS11
uniprot id: A0A8B7HS16
uniprot id: A0A8B7HS28
uniprot id: A0A8B7HS33
uniprot id: A0A8B7HUB6
uniprot id: A0A8B7WV39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Mitochondrion inner membrane

30608:CPE
gene id: 30608:CPE
uniprot id: A0A8C5Y691
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M14 family.
messages: Interacts with Secretogranin III/SCG3.
messages: Membrane
messages: Sorting receptor that directs prohormones to the regulated secretory pathway. Acts also as a prohormone processing enzyme in neuro/endocrine cells, removing dibasic residues from the C-terminal end of peptide hormone precursors after initial endoprotease cleavage.
messages: secretory vesicle membrane

30608:LOC105872845
gene id: 30608:LOC105872845
uniprot id: A0A8B7FY98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

30608:EHD4
gene id: 30608:EHD4
uniprot id: A0A8C5VSX1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

30608:LOC105878818
gene id: 30608:LOC105878818
uniprot id: A0A8C6EKS6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:YY2
gene id: 30608:YY2
uniprot id: A0A8B7HQF4
names: Similarity
messages: Belongs to the YY transcription factor family.

30608:NRP2
gene id: 30608:NRP2
uniprot id: A0A8B7EI87
uniprot id: A0A8B7EI88
uniprot id: A0A8B7EIM1
uniprot id: A0A8B7EJA7
uniprot id: A0A8B7EJB3
uniprot id: A0A8C6EKM7
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:FN3K
gene id: 30608:FN3K
uniprot id: A0A8B7H855
names: Similarity
messages: Belongs to the fructosamine kinase family.

30608:CHRNA10
gene id: 30608:CHRNA10
uniprot id: A0A8B7EYH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:UPF2
gene id: 30608:UPF2
uniprot id: A0A8B7EM09
names: Subcellular Location Annotation
messages: Cytoplasm

30608:BDKRB2
gene id: 30608:BDKRB2
uniprot id: A0A8B7I9M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.
messages: Membrane
messages: Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

30608:LOC105870490
gene id: 30608:LOC105870490
uniprot id: A0A8B7G8D3
names: Similarity
messages: Belongs to the PRAME family.

30608:RSG1
gene id: 30608:RSG1
uniprot id: A0A8B7G834
uniprot id: A0A8B7G897
uniprot id: A0A8B7G8R8
uniprot id: A0A8C5YDF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells.
messages: cilium basal body

30608:GRAMD1C
gene id: 30608:GRAMD1C
uniprot id: A0A8B7HXT0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:LOC105875326
gene id: 30608:LOC105875326
uniprot id: A0A8B7GXU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:GAPDH
gene id: 30608:GAPDH
uniprot id: A0A8B7G1N6
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

30608:COQ8B
gene id: 30608:COQ8B
uniprot id: A0A8B7H1P6
uniprot id: A0A8B7H3K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Membrane

30608:LRRC8C
gene id: 30608:LRRC8C
uniprot id: A0A8B7I941
uniprot id: A0A8C5VHD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

30608:ST3GAL3
gene id: 30608:ST3GAL3
uniprot id: A0A8B7H4N7
uniprot id: A0A8B7H4N8
uniprot id: A0A8B7H4N9
uniprot id: A0A8B7H4S4
uniprot id: A0A8B7H6Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

30608:SLC25A51
gene id: 30608:SLC25A51
uniprot id: A0A8B7XB09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:ARF6
gene id: 30608:ARF6
uniprot id: A0A8B7FWW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Cell membrane
messages: Cleavage furrow
messages: Endosome membrane
messages: Midbody ring
messages: Recycling endosome membrane
messages: filopodium membrane
messages: ruffle

30608:LOC105880462
gene id: 30608:LOC105880462
uniprot id: A0A8B7WRS0
names: Similarity
messages: Belongs to the PPase family.

30608:URGCP
gene id: 30608:URGCP
uniprot id: A0A8B7EPM7
uniprot id: A0A8B7EPS6
uniprot id: A0A8B7ERT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

30608:SLC28A3
gene id: 30608:SLC28A3
uniprot id: A0A8C5UWQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

30608:GPR179
gene id: 30608:GPR179
uniprot id: A0A8B7GG46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:TPP2
gene id: 30608:TPP2
uniprot id: A0A8B7FGI0
uniprot id: A0A8B7XFN2
uniprot id: A0A8C5VT35
names: Similarity
messages: Belongs to the peptidase S8 family.

30608:PIANP
gene id: 30608:PIANP
uniprot id: A0A8B7G1R3
uniprot id: A0A8B7G1R4
names: Subcellular Location Annotation
messages: Membrane

30608:PHLDA3
gene id: 30608:PHLDA3
uniprot id: A0A8B7EYS8
names: Subcellular Location Annotation
messages: Cytoplasm

30608:SLC22A3
gene id: 30608:SLC22A3
uniprot id: A0A8C5XCN9
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

30608:TOM1
gene id: 30608:TOM1
uniprot id: A0A8B7HWJ5
uniprot id: A0A8B7HYN3
uniprot id: A0A8C5UYX0
names: Similarity
messages: Belongs to the TOM1 family.

30608:CAMTA1
gene id: 30608:CAMTA1
uniprot id: A0A8B7I7M5
uniprot id: A0A8B7I9I9
uniprot id: A0A8B7IAV3
uniprot id: A0A8B7WQB9
uniprot id: A0A8B7WQC4
uniprot id: A0A8B7WQC8
uniprot id: A0A8B7WQD3
uniprot id: A0A8B7WQD8
uniprot id: A0A8B7WQE0
uniprot id: A0A8B7WQE5
uniprot id: A0A8B7WQE6
uniprot id: A0A8B7WQF1
uniprot id: A0A8B7WQF8
uniprot id: A0A8B7WQG3
uniprot id: A0A8B7WQG4
uniprot id: A0A8B7WQH0
uniprot id: A0A8B7WQH5
uniprot id: A0A8B7WRV0
uniprot id: A0A8B7WRV4
uniprot id: A0A8B7WRW5
names: Similarity
names: Subunit
messages: Belongs to the CAMTA family.
messages: May interact with calmodulin.

30608:ATF2
gene id: 30608:ATF2
uniprot id: A0A8B7X871
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

30608:LOC105856671
gene id: 30608:LOC105856671
uniprot id: A0A8B7EHC0
uniprot id: A0A8B7EHR5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

30608:GJB6
gene id: 30608:GJB6
uniprot id: A0A8B7HBD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

30608:DENND6B
gene id: 30608:DENND6B
uniprot id: A0A8B7I2Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Recycling endosome

30608:LOC105859905
gene id: 30608:LOC105859905
uniprot id: A0A8B7EWB9
names: Subcellular Location Annotation
messages: Membrane

30608:IL2RA
gene id: 30608:IL2RA
uniprot id: A0A8B7ER25
names: Caution
names: Function
names: Subunit
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.
messages: Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.

30608:LOC105862891
gene id: 30608:LOC105862891
uniprot id: A0A8B7X1X5
names: Similarity
messages: Belongs to the peptidase S14 family.

30608:TRIM3
gene id: 30608:TRIM3
uniprot id: A0A8B7HV75
uniprot id: A0A8B7HV81
uniprot id: A0A8B7HV95
names: Similarity
messages: Belongs to the TRIM/RBCC family.

30608:ZEB2
gene id: 30608:ZEB2
uniprot id: A0A8B7EXU5
uniprot id: A0A8B7EZP1
uniprot id: A0A8B7EZX6
names: Similarity
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

30608:KCNJ11
gene id: 30608:KCNJ11
uniprot id: A0A8B7HGY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ11 subfamily.
messages: Membrane

30608:DHX58
gene id: 30608:DHX58
uniprot id: A0A8B7EW07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

30608:FBN2
gene id: 30608:FBN2
uniprot id: A0A8B7EP30
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibrillin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:SLC35C2
gene id: 30608:SLC35C2
uniprot id: A0A8B7ETE3
uniprot id: A0A8B7EVD9
uniprot id: A0A8C5XKT7
names: Subcellular Location Annotation
messages: Membrane

30608:DKK2
gene id: 30608:DKK2
uniprot id: A0A8B7HCB5
uniprot id: A0A8B7HCB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

30608:PPP6R3
gene id: 30608:PPP6R3
uniprot id: A0A8B7FUK3
uniprot id: A0A8B7FUK6
uniprot id: A0A8B7FUK7
uniprot id: A0A8B7FUL0
uniprot id: A0A8B7FUL2
uniprot id: A0A8B7FUL5
uniprot id: A0A8B7FUQ4
uniprot id: A0A8B7FUQ9
uniprot id: A0A8B7FUR7
uniprot id: A0A8B7FVG4
uniprot id: A0A8B7FVK4
uniprot id: A0A8B7FVL4
uniprot id: A0A8B7FVL9
uniprot id: A0A8C5Y4Z8
names: Similarity
messages: Belongs to the SAPS family.

30608:KDM4B
gene id: 30608:KDM4B
uniprot id: A0A8B7G4F6
uniprot id: A0A8C5Y409
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM3 histone demethylase family.
messages: Nucleus

30608:SRFBP1
gene id: 30608:SRFBP1
uniprot id: A0A8B7I0D1
uniprot id: A0A8B7I359
names: Function
names: Subunit
messages: Interacts with SRF. Forms complexes with SRF and SRF cofactors ARID2, MYOCD and NKX2-5. Interacts with the N-terminus of SLC2A4.
messages: May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells.

30608:KDELR2
gene id: 30608:KDELR2
uniprot id: A0A8B7FY12
uniprot id: A0A8C6EJ57
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:PLPP2
gene id: 30608:PLPP2
uniprot id: A0A8B7F0N5
uniprot id: A0A8C5W9F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

30608:FAM69B
gene id: 30608:FAM69B
uniprot id: A0A8B7HJC2
names: Similarity
messages: Belongs to the DIPK family.

30608:F8
gene id: 30608:F8
uniprot id: A0A8B7X0H7
names: Similarity
messages: Belongs to the multicopper oxidase family.

30608:CD8B
gene id: 30608:CD8B
uniprot id: A0A8B7H337
names: Subcellular Location Annotation
messages: Membrane

30608:TRPV6
gene id: 30608:TRPV6
uniprot id: A0A8B7GKM5
uniprot id: A0A8B7XCU9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:GPNMB
gene id: 30608:GPNMB
uniprot id: A0A8B7H0J3
uniprot id: A0A8C5V0K1
names: Similarity
messages: Belongs to the PMEL/NMB family.

30608:MAP3K10
gene id: 30608:MAP3K10
uniprot id: A0A8B7H1M6
uniprot id: A0A8C5XUJ7
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

30608:GPN1
gene id: 30608:GPN1
uniprot id: A0A8B7I2E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

30608:LOC105875324
gene id: 30608:LOC105875324
uniprot id: A0A8B7GW19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

30608:TMEM186
gene id: 30608:TMEM186
uniprot id: A0A8B7HS71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM186 family.
messages: Membrane

30608:SLC25A30
gene id: 30608:SLC25A30
uniprot id: A0A8B7HKW9
uniprot id: A0A8B7HKX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:INPPL1
gene id: 30608:INPPL1
uniprot id: A0A8C5XFZ5
names: Subcellular Location Annotation
messages: Basal cell membrane
messages: spindle pole

30608:WSCD2
gene id: 30608:WSCD2
uniprot id: A0A8B7FT67
uniprot id: A0A8C5V602
names: Function
names: Similarity
messages: Belongs to the WSCD family.
messages: Sialate:O-sulfotransferase which catalyzes 8-O-sulfation at the Sia-glycan level using 3'-phosphoadenosine 5'-phosphosulfate (PAPS) as a donor, forming 8-O-sulfated Sia (Sia8S)-glycans.

30608:INTS11
gene id: 30608:INTS11
uniprot id: A0A8C5W365
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.
messages: Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, INTS11/CPSF3L and INTS12.
messages: Nucleus

30608:MTFR1L
gene id: 30608:MTFR1L
uniprot id: A0A8B7FCK4
uniprot id: A0A8B7FDC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

30608:CLDN8
gene id: 30608:CLDN8
uniprot id: A0A8B7HJI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

30608:STX7
gene id: 30608:STX7
uniprot id: A0A8B7EF73
names: Similarity
messages: Belongs to the syntaxin family.

30608:GANAB
gene id: 30608:GANAB
uniprot id: A0A8C6EKF9
uniprot id: A0A8C6EKX3
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

30608:SDPR
gene id: 30608:SDPR
uniprot id: A0A8B7H791
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

30608:KIF18A
gene id: 30608:KIF18A
uniprot id: A0A8B7F5P1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:FOXM1
gene id: 30608:FOXM1
uniprot id: A0A8B7X6D9
names: Subcellular Location Annotation
messages: Nucleus

30608:DLGAP5
gene id: 30608:DLGAP5
uniprot id: A0A8B7X1Y2
names: Similarity
messages: Belongs to the SAPAP family.

30608:CRYGN
gene id: 30608:CRYGN
uniprot id: A0A8B7HUC2
uniprot id: A0A8B7HUC4
uniprot id: A0A8C5Y1P8
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

30608:NDUFS8
gene id: 30608:NDUFS8
uniprot id: A0A8B7FUH5
uniprot id: A0A8B7FUM3
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

30608:NXPE1
gene id: 30608:NXPE1
uniprot id: A0A8B7F6U9
names: Similarity
messages: Belongs to the NXPE family.

30608:NTSR1
gene id: 30608:NTSR1
uniprot id: A0A8B7GXS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105869233
gene id: 30608:LOC105869233
uniprot id: A0A8B7G2T0
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

30608:LSM4
gene id: 30608:LSM4
uniprot id: A0A8B7EA74
uniprot id: A0A8B7EAW4
uniprot id: A0A8C5XZC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

30608:CCT8L2
gene id: 30608:CCT8L2
uniprot id: A0A8B7HUE7
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

30608:RIOK1
gene id: 30608:RIOK1
uniprot id: A0A8B7FKA2
uniprot id: A0A8B7FKE6
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

30608:CABS1
gene id: 30608:CABS1
uniprot id: A0A8B7HVN2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion inner membrane
messages: flagellum

30608:OTX2
gene id: 30608:OTX2
uniprot id: A0A8C5XXY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

30608:ADK
gene id: 30608:ADK
uniprot id: A0A8B7G0E5
uniprot id: A0A8B7G191
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

30608:CLTA
gene id: 30608:CLTA
uniprot id: A0A8B7GQD7
uniprot id: A0A8B7GQN2
uniprot id: A0A8B7GQT1
uniprot id: A0A8B7GRY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

30608:LOC105861315
gene id: 30608:LOC105861315
uniprot id: A0A8B7F2N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PPA2
gene id: 30608:PPA2
uniprot id: A0A8B7HC81
uniprot id: A0A8B7HC87
uniprot id: A0A8B7HC89
names: Similarity
messages: Belongs to the PPase family.

30608:RNF13
gene id: 30608:RNF13
uniprot id: A0A8B7HMG2
names: Subcellular Location Annotation
messages: Membrane

30608:KCNG3
gene id: 30608:KCNG3
uniprot id: A0A8B7FSP7
uniprot id: A0A8B7FSQ1
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105864417
gene id: 30608:LOC105864417
uniprot id: A0A8B7FH06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PTPN1
gene id: 30608:PTPN1
uniprot id: A0A8B7GFS7
uniprot id: A0A8C5V5Q8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

30608:HDAC2
gene id: 30608:HDAC2
uniprot id: A0A8B7X4S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

30608:IL4R
gene id: 30608:IL4R
uniprot id: A0A8B7HEX6
names: Function
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.

30608:PNPT1
gene id: 30608:PNPT1
uniprot id: A0A8B7H9E1
uniprot id: A0A8B7HC52
names: Similarity
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.

30608:CEP55
gene id: 30608:CEP55
uniprot id: A0A8B7GGF1
names: Subcellular Location Annotation
messages: Cytoplasm

30608:TM7SF3
gene id: 30608:TM7SF3
uniprot id: A0A8B7X6K7
names: Subcellular Location Annotation
messages: Membrane

30608:ORMDL1
gene id: 30608:ORMDL1
uniprot id: A0A8C6EF72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

30608:LGI3
gene id: 30608:LGI3
uniprot id: A0A8B7EJJ6
names: Subcellular Location Annotation
messages: Secreted

30608:BZW2
gene id: 30608:BZW2
uniprot id: A0A8B7HJR1
uniprot id: A0A8B7XDZ6
names: Similarity
messages: Belongs to the BZW family.

30608:STX19
gene id: 30608:STX19
uniprot id: A0A8B7G2W4
uniprot id: A0A8B7G2W7
uniprot id: A0A8C6EF67
names: Similarity
messages: Belongs to the syntaxin family.

30608:KRT222
gene id: 30608:KRT222
uniprot id: A0A8B7GEZ1
uniprot id: A0A8C5W0A2
names: Similarity
messages: Belongs to the intermediate filament family.

30608:PRPS2
gene id: 30608:PRPS2
uniprot id: A0A8B7HQX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

30608:MED31
gene id: 30608:MED31
uniprot id: A0A8C5VIV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 31 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

30608:IL33
gene id: 30608:IL33
uniprot id: A0A8C5V2J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family. Highly divergent.
messages: Chromosome
messages: Nucleus
messages: Secreted
messages: Vesicle
messages: secretory vesicle

30608:DSC3
gene id: 30608:DSC3
uniprot id: A0A8B7WR42
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

30608:ARRDC1
gene id: 30608:ARRDC1
uniprot id: A0A8B7HPX8
uniprot id: A0A8B7HPY2
uniprot id: A0A8B7HPY8
uniprot id: A0A8B7HPY9
uniprot id: A0A8B7HRQ3
uniprot id: A0A8B7HRQ8
uniprot id: A0A8B7HSC9
uniprot id: A0A8B7HSD3
names: Similarity
messages: Belongs to the arrestin family.

30608:CNKSR3
gene id: 30608:CNKSR3
uniprot id: A0A8C5UMV7
uniprot id: A0A8C5YCM3
names: Similarity
messages: Belongs to the CNKSR family.

30608:LOC105862354
gene id: 30608:LOC105862354
uniprot id: A0A8B7F7X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105875527
gene id: 30608:LOC105875527
uniprot id: A0A8C5XZT8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

30608:LOC105880312
gene id: 30608:LOC105880312
uniprot id: A0A8B7HHH9
names: Caution
names: Similarity
messages: Belongs to the DMBT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:INHBA
gene id: 30608:INHBA
uniprot id: A0A8C5W4V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

30608:ELL
gene id: 30608:ELL
uniprot id: A0A8B7WVN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

30608:SUMO3
gene id: 30608:SUMO3
uniprot id: A0A8B7HF21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

30608:LOC105864825
gene id: 30608:LOC105864825
uniprot id: A0A8B7WYU1
names: Similarity
messages: Belongs to the cyclin family.

30608:CHRNB1
gene id: 30608:CHRNB1
uniprot id: A0A8B7H5X9
uniprot id: A0A8B7H5Y7
uniprot id: A0A8B7H899
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:NUP133
gene id: 30608:NUP133
uniprot id: A0A8B7WP06
uniprot id: A0A8B7WQA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin Nup133 family.
messages: nuclear pore complex

30608:FURIN
gene id: 30608:FURIN
uniprot id: A0A8B7G9N9
names: Similarity
messages: Belongs to the peptidase S8 family.

30608:LOC105883373
gene id: 30608:LOC105883373
uniprot id: A0A8B7HUY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:HIKESHI
gene id: 30608:HIKESHI
uniprot id: A0A8C5UKJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.
messages: Belongs to the OPI10 family.
messages: Cytoplasm
messages: Forms an asymmetric homodimer; required for binding and nuclear import of HSP70 proteins. Interacts with ATP-bound HSP70 proteins.
messages: Nucleus
messages: cytosol

30608:LOC105875612
gene id: 30608:LOC105875612
uniprot id: A0A8B7GXC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

30608:LOC109730991
gene id: 30608:LOC109730991
uniprot id: A0A8B7X790
names: Subcellular Location Annotation
messages: Chromosome

30608:STRN4
gene id: 30608:STRN4
uniprot id: A0A8B7G486
uniprot id: A0A8B7G5K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

30608:UBLCP1
gene id: 30608:UBLCP1
uniprot id: A0A8B7GDF8
names: Subcellular Location Annotation
messages: Nucleus

30608:CHRNA2
gene id: 30608:CHRNA2
uniprot id: A0A8B7H3T2
uniprot id: A0A8B7WSF5
uniprot id: A0A8B7WSL3
uniprot id: A0A8C5UTB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:GRIN2B
gene id: 30608:GRIN2B
uniprot id: A0A8B7H192
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

30608:RBM42
gene id: 30608:RBM42
uniprot id: A0A8B7H2V7
uniprot id: A0A8C5YGQ4
names: Similarity
messages: Belongs to the RRM RBM42 family.

30608:TOB2
gene id: 30608:TOB2
uniprot id: A0A8C6EKP2
names: Similarity
messages: Belongs to the BTG family.

30608:BCL7C
gene id: 30608:BCL7C
uniprot id: A0A8B7GBT4
names: Similarity
messages: Belongs to the BCL7 family.

30608:FOXO3
gene id: 30608:FOXO3
uniprot id: A0A8B7FJ30
uniprot id: A0A8C5XIW3
names: Subcellular Location Annotation
messages: Nucleus

30608:PSMF1
gene id: 30608:PSMF1
uniprot id: A0A8B7FQ66
uniprot id: A0A8C5XN68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proteasome inhibitor PI31 family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.

30608:LOC105883075
gene id: 30608:LOC105883075
uniprot id: A0A8B7HTN8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

30608:PRPF4B
gene id: 30608:PRPF4B
uniprot id: A0A8C5W2Q5
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
messages: Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.

30608:EPS8L1
gene id: 30608:EPS8L1
uniprot id: A0A8B7H3X2
names: Similarity
messages: Belongs to the EPS8 family.

30608:LOC105882070
gene id: 30608:LOC105882070
uniprot id: A0A8B7HPB2
names: Similarity
messages: Belongs to the ARTD/PARP family.

30608:COLGALT2
gene id: 30608:COLGALT2
uniprot id: A0A8B7EBP6
uniprot id: A0A8C5VFY9
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

30608:ACOX2
gene id: 30608:ACOX2
uniprot id: A0A8B7I2A5
uniprot id: A0A8B7WL50
uniprot id: A0A8C5Y398
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

30608:LOC105883411
gene id: 30608:LOC105883411
uniprot id: A0A8B7X5R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ANKRD34B
gene id: 30608:ANKRD34B
uniprot id: A0A8B7GHG4
names: Similarity
messages: Belongs to the ANKRD34 family.

30608:SNX10
gene id: 30608:SNX10
uniprot id: A0A8B7GYP6
uniprot id: A0A8B7GYR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

30608:MYO9B
gene id: 30608:MYO9B
uniprot id: A0A8B7WY70
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

30608:LOC105865939
gene id: 30608:LOC105865939
uniprot id: A0A8B7FPX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Odorant receptor.

30608:LTB4R
gene id: 30608:LTB4R
uniprot id: A0A8B7FRT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

30608:TMEM2
gene id: 30608:TMEM2
uniprot id: A0A8B7GSN4
names: Similarity
messages: Belongs to the CEMIP family.

30608:TAS1R1
gene id: 30608:TAS1R1
uniprot id: A0A8B7I7N6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:MCM3
gene id: 30608:MCM3
uniprot id: A0A8B7G2N0
uniprot id: A0A8B7G2N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

30608:TRAPPC6B
gene id: 30608:TRAPPC6B
uniprot id: A0A8B7GIR5
uniprot id: A0A8C5XMT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

30608:LETM1
gene id: 30608:LETM1
uniprot id: A0A8B7EEJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LETM1 family.
messages: Membrane
messages: Mitochondrion inner membrane

30608:TULP4
gene id: 30608:TULP4
uniprot id: A0A8B7FZM2
uniprot id: A0A8B7FZN9
uniprot id: A0A8B7FZQ9
uniprot id: A0A8B7G0K1
uniprot id: A0A8B7G0X2
names: Similarity
messages: Belongs to the TUB family.

30608:CTSO
gene id: 30608:CTSO
uniprot id: A0A8B7HMY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

30608:IL4
gene id: 30608:IL4
uniprot id: A0A8B7G5R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-4/IL-13 family.
messages: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.
messages: Secreted

30608:LOC105879143
gene id: 30608:LOC105879143
uniprot id: A0A8B7HCN3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

30608:TMEM63B
gene id: 30608:TMEM63B
uniprot id: A0A8B7EWE3
uniprot id: A0A8C5VJM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

30608:LOC105864473
gene id: 30608:LOC105864473
uniprot id: A0A8B7FH71
names: Subcellular Location Annotation
messages: Membrane

30608:HIBCH
gene id: 30608:HIBCH
uniprot id: A0A8B7H753
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.
messages: Mitochondrion

30608:TNFRSF9
gene id: 30608:TNFRSF9
uniprot id: A0A8C5XP04
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:COPS8
gene id: 30608:COPS8
uniprot id: A0A8B7FQE0
uniprot id: A0A8C5VH39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN8 family.
messages: Cytoplasm
messages: Nucleus

30608:BTAF1
gene id: 30608:BTAF1
uniprot id: A0A8B7GEX3
uniprot id: A0A8B7GFP8
names: Subcellular Location Annotation
messages: Nucleus

30608:MFSD10
gene id: 30608:MFSD10
uniprot id: A0A8B7EGX1
names: Subcellular Location Annotation
messages: Membrane

30608:IL5
gene id: 30608:IL5
uniprot id: A0A8B7G5V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-5 family.
messages: Homodimer; disulfide-linked.
messages: Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts also on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation. Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively.
messages: Secreted

30608:ANKRD34A
gene id: 30608:ANKRD34A
uniprot id: A0A8B7G595
names: Similarity
messages: Belongs to the ANKRD34 family.

30608:RELL2
gene id: 30608:RELL2
uniprot id: A0A8B7F8X4
names: Similarity
messages: Belongs to the RELT family.

30608:LOC105884085
gene id: 30608:LOC105884085
uniprot id: A0A8B7HYE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ATG2A
gene id: 30608:ATG2A
uniprot id: A0A8B7H9T3
uniprot id: A0A8B7H9U1
uniprot id: A0A8B7H9U2
uniprot id: A0A8B7H9U5
uniprot id: A0A8B7HCL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Preautophagosomal structure membrane

30608:MTX2
gene id: 30608:MTX2
uniprot id: A0A8B7FK01
uniprot id: A0A8B7X868
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

30608:NGRN
gene id: 30608:NGRN
uniprot id: A0A8B7G8L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neugrin family.
messages: Forms a regulatory protein-RNA complex, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA. Interacts with 16S mt-rRNA; this interaction is direct.
messages: Mitochondrion membrane
messages: Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.

30608:BCL7A
gene id: 30608:BCL7A
uniprot id: A0A8B7WTV2
names: Similarity
messages: Belongs to the BCL7 family.

30608:TAAR5
gene id: 30608:TAAR5
uniprot id: A0A8B7ECY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

30608:LOC105865758
gene id: 30608:LOC105865758
uniprot id: A0A8B7FP01
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:LOC105856434
gene id: 30608:LOC105856434
uniprot id: A0A8B7EIX7
names: Similarity
messages: Belongs to the GAGE family.

30608:PRKDC
gene id: 30608:PRKDC
uniprot id: A0A8B7I3V7
uniprot id: A0A8B7I3W9
uniprot id: A0A8B7I5W5
uniprot id: A0A8B7I6X8
uniprot id: A0A8B7X9C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family.
messages: nucleolus

30608:SEPHS1
gene id: 30608:SEPHS1
uniprot id: A0A8B7WW86
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

30608:LOC105879981
gene id: 30608:LOC105879981
uniprot id: A0A8C5XJ34
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

30608:PRKAB2
gene id: 30608:PRKAB2
uniprot id: A0A8B7G571
uniprot id: A0A8B7G5Y7
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

30608:SLC16A11
gene id: 30608:SLC16A11
uniprot id: A0A8B7H7Z5
uniprot id: A0A8B7H7Z7
names: Subcellular Location Annotation
messages: Membrane

30608:L3HYPDH
gene id: 30608:L3HYPDH
uniprot id: A0A8B7X0Y4
uniprot id: A0A8C5UZX9
names: Similarity
messages: Belongs to the proline racemase family.

30608:LOC105864409
gene id: 30608:LOC105864409
uniprot id: A0A8B7FH28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MCCC2
gene id: 30608:MCCC2
uniprot id: A0A8B7HM53
names: Similarity
messages: Belongs to the AccD/PCCB family.

30608:AVL9
gene id: 30608:AVL9
uniprot id: A0A8B7ER75
uniprot id: A0A8C5W330
names: Subcellular Location Annotation
messages: Recycling endosome

30608:ROCK2
gene id: 30608:ROCK2
uniprot id: A0A8B7HH41
uniprot id: A0A8B7HH43
uniprot id: A0A8B7HH47
uniprot id: A0A8B7HHV9
uniprot id: A0A8B7HHW5
uniprot id: A0A8B7HJS1
uniprot id: A0A8B7HJS5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by RHOA binding. Inhibited by Y-27632.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer.
messages: Membrane
messages: Nucleus
messages: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
messages: centrosome

30608:ACSF2
gene id: 30608:ACSF2
uniprot id: A0A8B7I679
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

30608:SMARCA4
gene id: 30608:SMARCA4
uniprot id: A0A8B7I587
uniprot id: A0A8B7I791
uniprot id: A0A8B7I8E4
uniprot id: A0A8B7WW26
uniprot id: A0A8B7WW29
uniprot id: A0A8B7WWS5
uniprot id: A0A8B7WXS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

30608:LOC105883339
gene id: 30608:LOC105883339
uniprot id: A0A8B7HUT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ERRFI1
gene id: 30608:ERRFI1
uniprot id: A0A8C5Y2C2
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus

30608:RANGRF
gene id: 30608:RANGRF
uniprot id: A0A8B7H606
uniprot id: A0A8C5VLP6
names: Similarity
messages: Belongs to the MOG1 family.

30608:CHMP1A
gene id: 30608:CHMP1A
uniprot id: A0A8C5XZP6
names: Similarity
messages: Belongs to the SNF7 family.

30608:PROKR1
gene id: 30608:PROKR1
uniprot id: A0A8B7FBH0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:MRPS27
gene id: 30608:MRPS27
uniprot id: A0A8B7HM73
names: Subcellular Location Annotation
messages: Mitochondrion

30608:KAT2A
gene id: 30608:KAT2A
uniprot id: A0A8C5W337
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: centrosome

30608:FBP1
gene id: 30608:FBP1
uniprot id: A0A8B7F733
names: Similarity
messages: Belongs to the FBPase class 1 family.

30608:LOC105885147
gene id: 30608:LOC105885147
uniprot id: A0A8B7I6G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Odorant receptor.

30608:DPH5
gene id: 30608:DPH5
uniprot id: A0A8C5XC01
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

30608:LOC105873517
gene id: 30608:LOC105873517
uniprot id: A0A8B7GMB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

30608:LOC105861317
gene id: 30608:LOC105861317
uniprot id: A0A8C5W829
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105885430
gene id: 30608:LOC105885430
uniprot id: A0A8B7I7S1
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105886055
gene id: 30608:LOC105886055
uniprot id: A0A8B7I9A3
names: Similarity
messages: Belongs to the TAF9 family. CENP-S/MHF1 subfamily.

30608:TBC1D24
gene id: 30608:TBC1D24
uniprot id: A0A8B7EVK7
uniprot id: A0A8B7EVK8
uniprot id: A0A8B7WPA5
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasmic vesicle membrane
messages: Interacts with ARF6.
messages: Membrane
messages: Presynapse

30608:LOC109729221
gene id: 30608:LOC109729221
uniprot id: A0A8B7WV44
names: Similarity
names: Subunit
messages: Belongs to the GST superfamily. Mu family.
messages: Homodimer.

30608:MCOLN3
gene id: 30608:MCOLN3
uniprot id: A0A8B7F5Q4
uniprot id: A0A8B7F5R2
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

30608:ITIH3
gene id: 30608:ITIH3
uniprot id: A0A8B7GUI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

30608:ARID1B
gene id: 30608:ARID1B
uniprot id: A0A8B7FZK4
uniprot id: A0A8B7FZK9
uniprot id: A0A8B7FZL7
uniprot id: A0A8B7FZM4
uniprot id: A0A8B7FZP4
uniprot id: A0A8B7FZQ0
uniprot id: A0A8B7G0H9
uniprot id: A0A8B7G0I6
uniprot id: A0A8B7G0U6
uniprot id: A0A8B7G0W3
uniprot id: A0A8C5XH89
names: Subcellular Location Annotation
messages: Nucleus

30608:YTHDF2
gene id: 30608:YTHDF2
uniprot id: A0A8B7FCT6
uniprot id: A0A8B7FDL5
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

30608:GUCA2B
gene id: 30608:GUCA2B
uniprot id: A0A8B7GE81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

30608:MSI1
gene id: 30608:MSI1
uniprot id: A0A8B7FST7
uniprot id: A0A8C5VCQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

30608:SLC30A3
gene id: 30608:SLC30A3
uniprot id: A0A8B7HZJ4
uniprot id: A0A8B7I297
uniprot id: A0A8C5VY47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

30608:KCMF1
gene id: 30608:KCMF1
uniprot id: A0A8B7H0V2
names: Function
names: Similarity
messages: Belongs to the KCMF1 family.
messages: Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination.

30608:B3GAT2
gene id: 30608:B3GAT2
uniprot id: A0A8C5XKY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:LOC105871381
gene id: 30608:LOC105871381
uniprot id: A0A8B7GC19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PRTFDC1
gene id: 30608:PRTFDC1
uniprot id: A0A8B7H889
uniprot id: A0A8B7H898
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

30608:HSPA9
gene id: 30608:HSPA9
uniprot id: A0A8C5XID7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

30608:IDO2
gene id: 30608:IDO2
uniprot id: A0A8B7HB17
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

30608:ERGIC3
gene id: 30608:ERGIC3
uniprot id: A0A8B7FPJ8
uniprot id: A0A8C5XVK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

30608:TPM1
gene id: 30608:TPM1
uniprot id: A0A8B7FXC6
uniprot id: A0A8B7FXD0
uniprot id: A0A8B7FXD4
uniprot id: A0A8B7FXD9
uniprot id: A0A8B7FXE0
uniprot id: A0A8B7FXE6
uniprot id: A0A8B7FXI8
uniprot id: A0A8B7FXJ2
uniprot id: A0A8B7FXJ7
uniprot id: A0A8B7FYC2
uniprot id: A0A8B7FYC6
uniprot id: A0A8B7FYD1
uniprot id: A0A8B7FYD6
uniprot id: A0A8B7FYG0
uniprot id: A0A8B7FYG9
uniprot id: A0A8C5VCW4
uniprot id: A0A8C5VQX9
uniprot id: A0A8C5XKQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

30608:ST7L
gene id: 30608:ST7L
uniprot id: A0A8B7HB10
uniprot id: A0A8B7HB13
uniprot id: A0A8B7HB16
uniprot id: A0A8B7WRI5
uniprot id: A0A8B7WRJ0
uniprot id: A0A8B7WRM1
uniprot id: A0A8B7WRP3
uniprot id: A0A8B7WT05
uniprot id: A0A8C5XKF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

30608:FOXP2
gene id: 30608:FOXP2
uniprot id: A0A8B7XD15
names: Subcellular Location Annotation
messages: Nucleus

30608:AMACR
gene id: 30608:AMACR
uniprot id: A0A8B7FW59
uniprot id: A0A8B7FW62
uniprot id: A0A8C5YBK5
names: Similarity
messages: Belongs to the CoA-transferase III family.

30608:CORO6
gene id: 30608:CORO6
uniprot id: A0A8B7EMQ2
uniprot id: A0A8B7EPY2
names: Similarity
messages: Belongs to the WD repeat coronin family.

30608:SLC37A2
gene id: 30608:SLC37A2
uniprot id: A0A8B7FHJ4
uniprot id: A0A8B7FHM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucose levels.
messages: Membrane

30608:DPT
gene id: 30608:DPT
uniprot id: A0A8B7HNN8
names: Similarity
messages: Belongs to the dermatopontin family.

30608:SLC22A14
gene id: 30608:SLC22A14
uniprot id: A0A8B7FS62
names: Subcellular Location Annotation
messages: Membrane

30608:CXCR2
gene id: 30608:CXCR2
uniprot id: A0A8B7X9B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MAGT1
gene id: 30608:MAGT1
uniprot id: A0A8B7WYN3
uniprot id: A0A8B7WYN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:SERPINB8
gene id: 30608:SERPINB8
uniprot id: A0A8B7H3D4
uniprot id: A0A8C5VSK1
names: Similarity
messages: Belongs to the serpin family.

30608:FAM234B
gene id: 30608:FAM234B
uniprot id: A0A8B7H1A8
names: Similarity
messages: Belongs to the FAM234 family.

30608:PHKG2
gene id: 30608:PHKG2
uniprot id: A0A8B7GBU4
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

30608:NCOR1
gene id: 30608:NCOR1
uniprot id: A0A8B7EFN2
uniprot id: A0A8B7EFP0
uniprot id: A0A8B7EFP2
uniprot id: A0A8B7EG57
uniprot id: A0A8B7EG64
uniprot id: A0A8B7EGG9
uniprot id: A0A8B7EGH8
uniprot id: A0A8B7EGJ1
uniprot id: A0A8B7EI63
uniprot id: A0A8B7EI71
uniprot id: A0A8B7WN02
uniprot id: A0A8C5V8X0
names: Similarity
messages: Belongs to the N-CoR nuclear receptor corepressors family.

30608:CLPTM1
gene id: 30608:CLPTM1
uniprot id: A0A8B7G3W9
uniprot id: A0A8B7G592
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

30608:LOC105879477
gene id: 30608:LOC105879477
uniprot id: A0A8B7X7T4
names: Similarity
messages: Belongs to the SPATA31 family.

30608:LTBP2
gene id: 30608:LTBP2
uniprot id: A0A8B7X0N6
uniprot id: A0A8B7X0N7
uniprot id: A0A8C5W1X0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:SNX8
gene id: 30608:SNX8
uniprot id: A0A8B7FY40
uniprot id: A0A8B7FZ34
uniprot id: A0A8B7FZ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

30608:LOC105883394
gene id: 30608:LOC105883394
uniprot id: A0A8B7HX50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ZDHHC20
gene id: 30608:ZDHHC20
uniprot id: A0A8B7HBG8
uniprot id: A0A8B7HBG9
uniprot id: A0A8B7HBH0
uniprot id: A0A8C5UQD7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

30608:ACADS
gene id: 30608:ACADS
uniprot id: A0A8B7WTD8
uniprot id: A0A8C5YC67
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

30608:PEMT
gene id: 30608:PEMT
uniprot id: A0A8B7F6F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure. Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

30608:LOC105883486
gene id: 30608:LOC105883486
uniprot id: A0A8B7HXJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NAB2
gene id: 30608:NAB2
uniprot id: A0A8B7H7H2
uniprot id: A0A8C5XV50
uniprot id: A0A8C6EKA8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

30608:OCIAD1
gene id: 30608:OCIAD1
uniprot id: A0A8C5XT50
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OCIAD1 family.
messages: Endosome
messages: Interacts with STAT3.
messages: Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes.
messages: The OCIA domain is necessary and sufficient for endosomal localization.

30608:ADIPOR1
gene id: 30608:ADIPOR1
uniprot id: A0A8B7EWP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

30608:LOC105883473
gene id: 30608:LOC105883473
uniprot id: A0A8B7HVC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:EIF1AD
gene id: 30608:EIF1AD
uniprot id: A0A8B7HA86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EIF1AD family.
messages: Interacts with GAPDH and STAT1.
messages: Plays a role into cellular response to oxidative stress. Decreases cell proliferation.

30608:P4HA2
gene id: 30608:P4HA2
uniprot id: A0A8B7G6G3
uniprot id: A0A8B7WR59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

30608:MTMR11
gene id: 30608:MTMR11
uniprot id: A0A8B7FLN6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

30608:SORL1
gene id: 30608:SORL1
uniprot id: A0A8B7I3J5
uniprot id: A0A8B7I3L3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS10-related sortilin family. SORL1 subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Recycling endosome membrane
messages: Secreted
messages: multivesicular body membrane
messages: secretory vesicle membrane
messages: trans-Golgi network membrane

30608:KRT5
gene id: 30608:KRT5
uniprot id: A0A8B7G975
names: Similarity
messages: Belongs to the intermediate filament family.

30608:SAP30L
gene id: 30608:SAP30L
uniprot id: A0A8B7FQ46
names: Similarity
messages: Belongs to the SAP30 family.

30608:MOSPD3
gene id: 30608:MOSPD3
uniprot id: A0A8B7FZN3
names: Subcellular Location Annotation
messages: Membrane

30608:PPP2R2D
gene id: 30608:PPP2R2D
uniprot id: A0A8B7HHZ6
uniprot id: A0A8B7HI19
uniprot id: A0A8B7HIW7
uniprot id: A0A8B7WMA3
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

30608:TSPAN12
gene id: 30608:TSPAN12
uniprot id: A0A8B7FU91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

30608:TTC21A
gene id: 30608:TTC21A
uniprot id: A0A8B7WZZ0
uniprot id: A0A8B7X0H9
uniprot id: A0A8B7X0I6
uniprot id: A0A8B7X137
uniprot id: A0A8B7X1N7
uniprot id: A0A8C5YFM9
names: Similarity
messages: Belongs to the TTC21 family.

30608:LOC109730202
gene id: 30608:LOC109730202
uniprot id: A0A8B7WYC2
uniprot id: A0A8B7WZA1
names: Similarity
messages: Belongs to the MDFI family.

30608:PHTF2
gene id: 30608:PHTF2
uniprot id: A0A8B7F559
uniprot id: A0A8B7F578
uniprot id: A0A8B7F5A4
uniprot id: A0A8B7F5B9
uniprot id: A0A8B7F5C4
uniprot id: A0A8C5W495
names: Subcellular Location Annotation
messages: Membrane

30608:ADCY9
gene id: 30608:ADCY9
uniprot id: A0A8B7EV22
uniprot id: A0A8B7WPL8
uniprot id: A0A8B7WQU6
uniprot id: A0A8C5XTQ7
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

30608:DHH
gene id: 30608:DHH
uniprot id: A0A8C5V9V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

30608:LOC105875153
gene id: 30608:LOC105875153
uniprot id: A0A8B7GUW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:IPO8
gene id: 30608:IPO8
uniprot id: A0A8C5XM85
names: Subcellular Location Annotation
messages: Cytoplasm

30608:LOC105879496
gene id: 30608:LOC105879496
uniprot id: A0A8B7WKN4
uniprot id: A0A8B7WKQ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LIPF
gene id: 30608:LIPF
uniprot id: A0A8C5V221
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

30608:LOC105861288
gene id: 30608:LOC105861288
uniprot id: A0A8B7F2K3
names: Subcellular Location Annotation
messages: Membrane

30608:NKX6-2
gene id: 30608:NKX6-2
uniprot id: A0A8B7FR16
names: Subcellular Location Annotation
messages: Nucleus

30608:CHAC2
gene id: 30608:CHAC2
uniprot id: A0A8B7H9A0
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

30608:MRPL58
gene id: 30608:MRPL58
uniprot id: A0A8C5UXA5
names: Subcellular Location Annotation
messages: Mitochondrion

30608:LOC105859896
gene id: 30608:LOC105859896
uniprot id: A0A8B7EWB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SCNN1G
gene id: 30608:SCNN1G
uniprot id: A0A8B7HF30
uniprot id: A0A8B7HF52
names: Subcellular Location Annotation
messages: Membrane

30608:CADM2
gene id: 30608:CADM2
uniprot id: A0A8B7EN72
uniprot id: A0A8B7END6
uniprot id: A0A8B7EQE3
names: Similarity
messages: Belongs to the nectin family.

30608:LOC105883390
gene id: 30608:LOC105883390
uniprot id: A0A8B7HX53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ASB13
gene id: 30608:ASB13
uniprot id: A0A8B7WWZ0
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

30608:TTC39B
gene id: 30608:TTC39B
uniprot id: A0A8B7GPN6
uniprot id: A0A8B7GPP1
uniprot id: A0A8B7GPY3
uniprot id: A0A8B7GR81
names: Similarity
messages: Belongs to the TTC39 family.

30608:HSDL2
gene id: 30608:HSDL2
uniprot id: A0A8B7GN97
uniprot id: A0A8B7GP28
names: Subcellular Location Annotation
messages: Peroxisome

30608:MSLN
gene id: 30608:MSLN
uniprot id: A0A8C5VLK8
names: Similarity
messages: Belongs to the mesothelin family.

30608:NDNF
gene id: 30608:NDNF
uniprot id: A0A8C5VWP6
names: Subcellular Location Annotation
messages: Secreted

30608:LOC105874756
gene id: 30608:LOC105874756
uniprot id: A0A8B7GSL9
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

30608:NIPBL
gene id: 30608:NIPBL
uniprot id: A0A8B7EC13
uniprot id: A0A8B7EC30
uniprot id: A0A8B7ECN9
uniprot id: A0A8B7EEQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC2/Nipped-B family.
messages: Nucleus

30608:DDX10
gene id: 30608:DDX10
uniprot id: A0A8C5XZR0
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

30608:LOC105872479
gene id: 30608:LOC105872479
uniprot id: A0A8B7GHD1
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:UNC45A
gene id: 30608:UNC45A
uniprot id: A0A8B7G979
uniprot id: A0A8C5VNG0
names: Subcellular Location Annotation
messages: perinuclear region

30608:ATPIF1
gene id: 30608:ATPIF1
uniprot id: A0A8C5VP01
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase inhibitor family.
messages: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase.
messages: Forms an alpha-helical dimer with monomers associated via an antiparallel alpha-helical coiled coil, leaving each N-terminal inhibitory region accessible for interaction with an F1 catalytic domain. The inhibitory N-terminal region binds the alpha(ADP-bound)-beta(ADP-bound) (ATP5F1A-ATP5F1B) interface of F1-ATPase, and also contact the central gamma subunit (ATP5F1C). This dimeric state is favored by pH values below 7.0, and at higher values the dimers associate to form inactive homotetramer, where the inhibitory region is occluded, masking its inhibitory activity.
messages: Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0.
messages: Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
messages: Mitochondrion

30608:THEMIS2
gene id: 30608:THEMIS2
uniprot id: A0A8C5Y8B9
names: Similarity
messages: Belongs to the themis family.

30608:MED4
gene id: 30608:MED4
uniprot id: A0A8B7FZG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 4 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

30608:FGF22
gene id: 30608:FGF22
uniprot id: A0A8B7F0M8
uniprot id: A0A8B7F2D7
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

30608:HDAC5
gene id: 30608:HDAC5
uniprot id: A0A8B7HVM1
uniprot id: A0A8B7HVN8
uniprot id: A0A8B7HXT2
uniprot id: A0A8B7HXX7
uniprot id: A0A8B7WNA7
uniprot id: A0A8C5Y7Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

30608:TMEM97
gene id: 30608:TMEM97
uniprot id: A0A8B7EMP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TMEM97/sigma-2 receptor family.
messages: Endoplasmic reticulum membrane
messages: Interacts with NPC1.
messages: Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

30608:LOC105883494
gene id: 30608:LOC105883494
uniprot id: A0A8B7HVG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PRUNE2
gene id: 30608:PRUNE2
uniprot id: A0A8B7G012
uniprot id: A0A8B7G025
uniprot id: A0A8B7G029
uniprot id: A0A8B7G037
uniprot id: A0A8B7G043
uniprot id: A0A8B7G045
uniprot id: A0A8B7G053
uniprot id: A0A8B7G0Z0
uniprot id: A0A8B7G0Z7
uniprot id: A0A8B7G103
uniprot id: A0A8B7G1C8
uniprot id: A0A8B7G1D6
uniprot id: A0A8B7G1E2
uniprot id: A0A8C5Y6P0
names: Similarity
messages: Belongs to the PPase class C family. Prune subfamily.

30608:KCNB2
gene id: 30608:KCNB2
uniprot id: A0A8C5W334
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.2/KCNB2 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: dendrite

30608:LOC105860455
gene id: 30608:LOC105860455
uniprot id: A0A8B7WYG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

30608:SNX31
gene id: 30608:SNX31
uniprot id: A0A8B7X9U1
uniprot id: A0A8B7X9U5
uniprot id: A0A8B7XAJ2
uniprot id: A0A8B7XBI9
uniprot id: A0A8B7XBY1
uniprot id: A0A8B7XBY6
uniprot id: A0A8C5UWU0
names: Similarity
messages: Belongs to the sorting nexin family.

30608:CD3E
gene id: 30608:CD3E
uniprot id: A0A8B7GZE0
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105882593
gene id: 30608:LOC105882593
uniprot id: A0A8B7HRS8
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:TPX2
gene id: 30608:TPX2
uniprot id: A0A8B7FN22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPX2 family.
messages: Nucleus
messages: spindle pole

30608:SYK
gene id: 30608:SYK
uniprot id: A0A8B7GZV0
uniprot id: A0A8B7GZV3
uniprot id: A0A8B7H014
uniprot id: A0A8B7H1T9
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

30608:ADAMTS8
gene id: 30608:ADAMTS8
uniprot id: A0A8B7HMD3
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:LOC105874380
gene id: 30608:LOC105874380
uniprot id: A0A8C5W3W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SNX14
gene id: 30608:SNX14
uniprot id: A0A8B7F7K6
uniprot id: A0A8B7F7U7
uniprot id: A0A8B7X658
uniprot id: A0A8C5W0M4
names: Similarity
messages: Belongs to the sorting nexin family.

30608:KDM6A
gene id: 30608:KDM6A
uniprot id: A0A8B7FLK2
uniprot id: A0A8B7FLL7
uniprot id: A0A8B7FLM0
uniprot id: A0A8B7FLM2
uniprot id: A0A8B7FMR7
uniprot id: A0A8B7FMS1
uniprot id: A0A8C6EKP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTX family.
messages: Nucleus

30608:CENPH
gene id: 30608:CENPH
uniprot id: A0A8B7HMS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-H/MCM16 family.
messages: Nucleus
messages: kinetochore

30608:SLC5A2
gene id: 30608:SLC5A2
uniprot id: A0A8C5UTI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

30608:CASP3
gene id: 30608:CASP3
uniprot id: A0A8B7HT85
uniprot id: A0A8B7HTM7
names: Similarity
messages: Belongs to the peptidase C14A family.

30608:RELN
gene id: 30608:RELN
uniprot id: A0A8B7F3H2
uniprot id: A0A8B7F4C1
uniprot id: A0A8B7F4C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the reelin family.
messages: Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Oligomer of disulfide-linked homodimers. Binds to the ectodomains of VLDLR and LRP8/APOER2.
messages: extracellular matrix

30608:AGK
gene id: 30608:AGK
uniprot id: A0A8B7GKI8
uniprot id: A0A8B7GKJ0
uniprot id: A0A8B7GL61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AGK family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

30608:LOC105883776
gene id: 30608:LOC105883776
uniprot id: A0A8B7HX03
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

30608:LOC105861329
gene id: 30608:LOC105861329
uniprot id: A0A8B7F461
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:C4BPA
gene id: 30608:C4BPA
uniprot id: A0A8B7G2J6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:KATNAL2
gene id: 30608:KATNAL2
uniprot id: A0A8B7F134
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 2 sub-subfamily.
messages: Cytoplasm
messages: Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
messages: cytoskeleton
messages: spindle
messages: spindle pole

30608:SENP1
gene id: 30608:SENP1
uniprot id: A0A8B7FN80
uniprot id: A0A8B7FNN9
uniprot id: A0A8B7FPG5
uniprot id: A0A8C5XHL0
names: Similarity
messages: Belongs to the peptidase C48 family.

30608:IFNK
gene id: 30608:IFNK
uniprot id: A0A8B7XDB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

30608:CCNT1
gene id: 30608:CCNT1
uniprot id: A0A8B7FWU3
uniprot id: A0A8C5XV25
names: Similarity
messages: Belongs to the cyclin family.

30608:ALG11
gene id: 30608:ALG11
uniprot id: A0A8B7HKQ8
uniprot id: A0A8B7HKR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly.

30608:ATP2A1
gene id: 30608:ATP2A1
uniprot id: A0A8B7FY14
uniprot id: A0A8B7FZ47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

30608:NMI
gene id: 30608:NMI
uniprot id: A0A8B7HEJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NMI family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

30608:LHFPL3
gene id: 30608:LHFPL3
uniprot id: A0A8B7F3D0
uniprot id: A0A8B7F4A7
names: Subcellular Location Annotation
messages: Membrane

30608:RBFOX2
gene id: 30608:RBFOX2
uniprot id: A0A8B7HWJ7
uniprot id: A0A8B7HWK0
uniprot id: A0A8B7HWK3
uniprot id: A0A8B7HWK5
uniprot id: A0A8B7HWK8
uniprot id: A0A8B7HWL2
uniprot id: A0A8B7HWL3
uniprot id: A0A8B7HWL6
uniprot id: A0A8B7HWL7
uniprot id: A0A8B7HWM3
uniprot id: A0A8B7HWM5
uniprot id: A0A8B7HYN8
uniprot id: A0A8B7HYP4
uniprot id: A0A8B7HYP9
uniprot id: A0A8B7HYQ4
uniprot id: A0A8B7HYQ8
uniprot id: A0A8B7HZ15
uniprot id: A0A8B7HZ20
uniprot id: A0A8B7HZ25
uniprot id: A0A8B7HZ30
uniprot id: A0A8B7HZ35
uniprot id: A0A8B7X6E5
uniprot id: A0A8B7X851
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

30608:RBP7
gene id: 30608:RBP7
uniprot id: A0A8B7X1F4
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

30608:LYPD2
gene id: 30608:LYPD2
uniprot id: A0A8C5XAT1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:YWHAG
gene id: 30608:YWHAG
uniprot id: A0A8C5VYM3
names: Similarity
messages: Belongs to the 14-3-3 family.

30608:DHDH
gene id: 30608:DHDH
uniprot id: A0A8B7FM30
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

30608:HMGA1
gene id: 30608:HMGA1
uniprot id: A0A8B7F472
uniprot id: A0A8B7X614
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGA family.
messages: Nucleus

30608:LAMTOR1
gene id: 30608:LAMTOR1
uniprot id: A0A8B7F058
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

30608:NOXA1
gene id: 30608:NOXA1
uniprot id: A0A8B7XDA1
names: Similarity
messages: Belongs to the NCF2/NOXA1 family.

30608:TSPAN5
gene id: 30608:TSPAN5
uniprot id: A0A8B7WXL4
uniprot id: A0A8C5VNZ3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:HPGD
gene id: 30608:HPGD
uniprot id: A0A8C5YCJ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:ACSM5
gene id: 30608:ACSM5
uniprot id: A0A8B7EBG7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

30608:ADSSL1
gene id: 30608:ADSSL1
uniprot id: A0A8B7F3U6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

30608:TMEM18
gene id: 30608:TMEM18
uniprot id: A0A8B7HM63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM18 family.
messages: Membrane
messages: Nucleus membrane

30608:CORO7
gene id: 30608:CORO7
uniprot id: A0A8B7EVB0
names: Similarity
messages: Belongs to the WD repeat coronin family.

30608:LOC105866529
gene id: 30608:LOC105866529
uniprot id: A0A8B7FR00
names: Subcellular Location Annotation
messages: Membrane

30608:LRP3
gene id: 30608:LRP3
uniprot id: A0A8B7H359
uniprot id: A0A8B7H561
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:ETV3
gene id: 30608:ETV3
uniprot id: A0A8B7GJL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

30608:CRISP3
gene id: 30608:CRISP3
uniprot id: A0A8B7G2Q5
uniprot id: A0A8B7G2Q7
uniprot id: A0A8B7G3J9
names: Caution
names: Similarity
messages: Belongs to the CRISP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:HMCES
gene id: 30608:HMCES
uniprot id: A0A8B7WUT0
names: Function
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.
messages: Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA: forms a stable thiazolidine linkage between a ring-opened abasic site and the alpha-amino and sulfhydryl substituents of its N-terminal catalytic cysteine residue. The HMCES DNA-protein cross-link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endonucleases that are error-prone and would generate mutations and double-strand breaks. Has preference for ssDNA, but can also accommodate double-stranded DNA with 3' or 5' overhang (dsDNA), and dsDNA-ssDNA 3' junction.

30608:COQ6
gene id: 30608:COQ6
uniprot id: A0A8C5VUN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Cell projection
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ7.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Golgi apparatus
messages: Mitochondrion inner membrane

30608:PURG
gene id: 30608:PURG
uniprot id: A0A8B7HQV2
uniprot id: A0A8B7HRL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

30608:GJC1
gene id: 30608:GJC1
uniprot id: A0A8B7HVU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins. Interacts with CNST.
messages: Belongs to the connexin family. Gamma-type subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

30608:HMGB1
gene id: 30608:HMGB1
uniprot id: A0A8B7F3Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

30608:RNF145
gene id: 30608:RNF145
uniprot id: A0A8B7GCS2
uniprot id: A0A8B7WVE0
names: Subcellular Location Annotation
messages: Membrane

30608:FTCD
gene id: 30608:FTCD
uniprot id: A0A8C5VGN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds and promotes bundling of vimentin filaments originating from the Golgi.
messages: Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool.
messages: Golgi apparatus
messages: Homooctamer, including four polyglutamate binding sites. The subunits are arranged as a tetramer of dimers, and form a planar ring-shaped structure.
messages: In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family.
messages: In the N-terminal section; belongs to the formiminotransferase family.
messages: centriole

30608:DCTN5
gene id: 30608:DCTN5
uniprot id: A0A8C5VH15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 5 subfamily.
messages: cytoskeleton

30608:LOC105866547
gene id: 30608:LOC105866547
uniprot id: A0A8B7FQY7
uniprot id: A0A8B7FRH9
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

30608:HNRNPA3
gene id: 30608:HNRNPA3
uniprot id: A0A8B7X861
uniprot id: A0A8B7X863
uniprot id: A0A8B7XA61
names: Subcellular Location Annotation
messages: Nucleus

30608:SLC35F6
gene id: 30608:SLC35F6
uniprot id: A0A8C5USS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLC35F solute transporter family.
messages: Interacts with SLC25A5.
messages: May play a role as a nucleotide-sugar transporter.
messages: Membrane
messages: Mitochondrion

30608:CILP
gene id: 30608:CILP
uniprot id: A0A8B7FXH4
uniprot id: A0A8C5W343
names: Subcellular Location Annotation
messages: extracellular matrix

30608:LOC105870818
gene id: 30608:LOC105870818
uniprot id: A0A8B7X152
names: Subcellular Location Annotation
messages: Membrane

30608:RTN4IP1
gene id: 30608:RTN4IP1
uniprot id: A0A8B7FJ48
uniprot id: A0A8B7FJ54
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

30608:FOXP1
gene id: 30608:FOXP1
uniprot id: A0A8B7WYA4
uniprot id: A0A8B7WYA5
uniprot id: A0A8B7WYB5
uniprot id: A0A8B7WYR8
uniprot id: A0A8B7WYS8
uniprot id: A0A8B7WYT3
uniprot id: A0A8B7X008
uniprot id: A0A8B7X017
uniprot id: A0A8C5VLN9
uniprot id: A0A8C5VRI9
names: Subcellular Location Annotation
messages: Nucleus

30608:TIMM8A
gene id: 30608:TIMM8A
uniprot id: A0A8C5XN44
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

30608:SNW1
gene id: 30608:SNW1
uniprot id: A0A8B7EVL7
uniprot id: A0A8B7EVM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNW family.
messages: Identified in the spliceosome C complex.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

30608:MAEL
gene id: 30608:MAEL
uniprot id: A0A8B7EZ79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the maelstrom family.
messages: Nucleus
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage.

30608:PFKFB4
gene id: 30608:PFKFB4
uniprot id: A0A8B7GTD4
uniprot id: A0A8B7GTJ3
uniprot id: A0A8B7GTK7
uniprot id: A0A8B7GV51
uniprot id: A0A8C5VB42
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

30608:SLC9A4
gene id: 30608:SLC9A4
uniprot id: A0A8C5YAG6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Interacts with CHP1 and CHP2.
messages: Membrane

30608:LYRM1
gene id: 30608:LYRM1
uniprot id: A0A8B7I483
names: Similarity
messages: Belongs to the complex I LYR family.

30608:LOC105871459
gene id: 30608:LOC105871459
uniprot id: A0A8B7GCW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NRG3
gene id: 30608:NRG3
uniprot id: A0A8B7GC46
uniprot id: A0A8B7GC50
uniprot id: A0A8B7GC51
uniprot id: A0A8B7GCN8
uniprot id: A0A8B7GCQ1
uniprot id: A0A8B7GCQ8
uniprot id: A0A8B7GD45
uniprot id: A0A8B7WLW0
uniprot id: A0A8B7WMW6
uniprot id: A0A8C5VWM3
names: Caution
names: Similarity
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:NDRG3
gene id: 30608:NDRG3
uniprot id: A0A8B7FNR3
uniprot id: A0A8B7FNR9
uniprot id: A0A8B7FNX9
uniprot id: A0A8B7FNZ0
uniprot id: A0A8B7FNZ5
uniprot id: A0A8B7FP76
uniprot id: A0A8B7FQ14
uniprot id: A0A8B7FQ19
uniprot id: A0A8B7WQX0
names: Similarity
messages: Belongs to the NDRG family.

30608:MMAB
gene id: 30608:MMAB
uniprot id: A0A8B7FSC3
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

30608:P2RY2
gene id: 30608:P2RY2
uniprot id: A0A8B7F0J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TNFSF13B
gene id: 30608:TNFSF13B
uniprot id: A0A8B7FGD1
names: Similarity
messages: Belongs to the tumor necrosis factor family.

30608:GMFB
gene id: 30608:GMFB
uniprot id: A0A8B7FWW3
uniprot id: A0A8B7X2A9
uniprot id: A0A8C5VE73
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

30608:ADAMTS12
gene id: 30608:ADAMTS12
uniprot id: A0A8B7XCV1
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:LOC105884097
gene id: 30608:LOC105884097
uniprot id: A0A8B7X5K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:AR
gene id: 30608:AR
uniprot id: A0A8B7ECA7
names: Similarity
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.

30608:LOC105885158
gene id: 30608:LOC105885158
uniprot id: A0A8B7I3E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Odorant receptor.

30608:TRPC6
gene id: 30608:TRPC6
uniprot id: A0A8B7GS71
uniprot id: A0A8B7GTJ6
uniprot id: A0A8B7X560
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105883051
gene id: 30608:LOC105883051
uniprot id: A0A8B7WYH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

30608:LOC105864336
gene id: 30608:LOC105864336
uniprot id: A0A8B7FGQ7
names: Subcellular Location Annotation
messages: Nucleus

30608:MRPL19
gene id: 30608:MRPL19
uniprot id: A0A8C5USM2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

30608:TGIF1
gene id: 30608:TGIF1
uniprot id: A0A8B7F1L4
uniprot id: A0A8B7F1L5
uniprot id: A0A8B7F3C3
uniprot id: A0A8B7F3P7
uniprot id: A0A8C5YCS0
names: Subcellular Location Annotation
messages: Nucleus

30608:MAP3K7
gene id: 30608:MAP3K7
uniprot id: A0A8B7FDT2
uniprot id: A0A8B7FDZ8
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by pro-inflammatory cytokines and in response to physical and chemical stresses, including osmotic stress, oxidative stress, arsenic and ultraviolet light irradiation. Activated by 'Lys-63'-linked polyubiquitination and by autophosphorylation.
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cytoplasm

30608:UTP14A
gene id: 30608:UTP14A
uniprot id: A0A8B7FCI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP14 family.
messages: nucleolus

30608:PKIG
gene id: 30608:PKIG
uniprot id: A0A8B7HGK7
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

30608:ADAMTS1
gene id: 30608:ADAMTS1
uniprot id: A0A8B7GBF6
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:PNLIPRP2
gene id: 30608:PNLIPRP2
uniprot id: A0A8B7H3X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

30608:RFC4
gene id: 30608:RFC4
uniprot id: A0A8B7I2Y7
names: Similarity
messages: Belongs to the activator 1 small subunits family.

30608:NDUFS4
gene id: 30608:NDUFS4
uniprot id: A0A8B7FSZ1
uniprot id: A0A8B7FTX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Mitochondrion inner membrane

30608:LOC105862878
gene id: 30608:LOC105862878
uniprot id: A0A8B7FA39
uniprot id: A0A8C5VLI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

30608:LOC105867092
gene id: 30608:LOC105867092
uniprot id: A0A8C5V9L5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

30608:EIF3L
gene id: 30608:EIF3L
uniprot id: A0A8B7EQE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit L family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with RRN3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm

30608:LOC109731077
gene id: 30608:LOC109731077
uniprot id: A0A8B7X9Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

30608:LOC105874390
gene id: 30608:LOC105874390
uniprot id: A0A8C5W9R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:COG7
gene id: 30608:COG7
uniprot id: A0A8B7HFK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG7 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:CCT3
gene id: 30608:CCT3
uniprot id: A0A8B7GK43
uniprot id: A0A8C5VCV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

30608:PLXNA4
gene id: 30608:PLXNA4
uniprot id: A0A8B7EKP9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:PAQR8
gene id: 30608:PAQR8
uniprot id: A0A8B7G2K7
uniprot id: A0A8B7G3Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

30608:DYNC1LI1
gene id: 30608:DYNC1LI1
uniprot id: A0A8B7GNR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

30608:NELL2
gene id: 30608:NELL2
uniprot id: A0A8B7F6W7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:PFN1
gene id: 30608:PFN1
uniprot id: A0A8B7HD97
names: Similarity
messages: Belongs to the profilin family.

30608:CFDP1
gene id: 30608:CFDP1
uniprot id: A0A8B7GWN9
uniprot id: A0A8B7GWT8
names: Function
names: Subcellular Location Annotation
messages: May play a role during embryogenesis.
messages: kinetochore

30608:LOC105883423
gene id: 30608:LOC105883423
uniprot id: A0A8B7HX88
names: Subcellular Location Annotation
messages: Membrane

30608:CLCN7
gene id: 30608:CLCN7
uniprot id: A0A8B7EUP3
uniprot id: A0A8C5VMA9
uniprot id: A0A8C5VSW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

30608:STAT3
gene id: 30608:STAT3
uniprot id: A0A8B7ETY6
uniprot id: A0A8B7ETY9
uniprot id: A0A8B7ETZ0
uniprot id: A0A8B7EVY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

30608:MED30
gene id: 30608:MED30
uniprot id: A0A8B7FE98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

30608:KRT82
gene id: 30608:KRT82
uniprot id: A0A8B7GCC1
names: Similarity
messages: Belongs to the intermediate filament family.

30608:LOC105861295
gene id: 30608:LOC105861295
uniprot id: A0A8B7F445
names: Subcellular Location Annotation
messages: Membrane

30608:SOHLH2
gene id: 30608:SOHLH2
uniprot id: A0A8B7F6X2
uniprot id: A0A8B7F740
names: Subcellular Location Annotation
messages: Nucleus

30608:RAB21
gene id: 30608:RAB21
uniprot id: A0A8B7EI42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cleavage furrow
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: trans-Golgi network

30608:IL1RL2
gene id: 30608:IL1RL2
uniprot id: A0A8B7ENQ1
uniprot id: A0A8B7EPH0
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

30608:LOC105858021
gene id: 30608:LOC105858021
uniprot id: A0A8B7WVT4
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

30608:LOC105858542
gene id: 30608:LOC105858542
uniprot id: A0A8B7EQ73
uniprot id: A0A8B7EQB1
uniprot id: A0A8B7X756
uniprot id: A0A8B7X869
uniprot id: A0A8B7X8G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM227 family.
messages: Belongs to the RecA family. DMC1 subfamily.
messages: May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.
messages: Nucleus

30608:PNMT
gene id: 30608:PNMT
uniprot id: A0A8B7GF66
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

30608:CNDP1
gene id: 30608:CNDP1
uniprot id: A0A8C5V7G6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

30608:EVA1B
gene id: 30608:EVA1B
uniprot id: A0A8B7GDX8
names: Similarity
messages: Belongs to the EVA1 family.

30608:FXYD1
gene id: 30608:FXYD1
uniprot id: A0A8B7H4Z2
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the FXYD family.
messages: Cell membrane
messages: Membrane
messages: T-tubule
messages: caveola
messages: sarcolemma

30608:ERCC5
gene id: 30608:ERCC5
uniprot id: A0A8B7FG99
uniprot id: A0A8B7FHD9
uniprot id: A0A8C5Y5U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
messages: Nucleus

30608:ST8SIA1
gene id: 30608:ST8SIA1
uniprot id: A0A8B7HSI0
uniprot id: A0A8B7HUJ3
uniprot id: A0A8C5UR75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

30608:FOXN4
gene id: 30608:FOXN4
uniprot id: A0A8B7FSV3
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105871463
gene id: 30608:LOC105871463
uniprot id: A0A8B7GCC6
names: Similarity
messages: Belongs to the intermediate filament family.

30608:CTC1
gene id: 30608:CTC1
uniprot id: A0A8B7H642
uniprot id: A0A8C5V5R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTC1 family.
messages: Nucleus
messages: telomere

30608:MCOLN1
gene id: 30608:MCOLN1
uniprot id: A0A8B7I5L7
uniprot id: A0A8B7I5L8
uniprot id: A0A8B7I5Q9
uniprot id: A0A8B7I7M3
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

30608:MDFIC
gene id: 30608:MDFIC
uniprot id: A0A8B7EBX9
names: Similarity
messages: Belongs to the MDFI family.

30608:POC5
gene id: 30608:POC5
uniprot id: A0A8C5W635
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POC5 family.
messages: Essential for the assembly of the distal half of centrioles, required for centriole elongation.
messages: centriole

30608:AP2A1
gene id: 30608:AP2A1
uniprot id: A0A8B7FMJ9
uniprot id: A0A8C5XZB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif.
messages: coated pit

30608:TNS4
gene id: 30608:TNS4
uniprot id: A0A8B7GEZ7
uniprot id: A0A8B7GF03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

30608:TPD52
gene id: 30608:TPD52
uniprot id: A0A8B7X947
names: Similarity
messages: Belongs to the TPD52 family.

30608:LOC105866476
gene id: 30608:LOC105866476
uniprot id: A0A8B7FQJ9
uniprot id: A0A8B7FQQ2
uniprot id: A0A8B7FR42
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

30608:TIMM50
gene id: 30608:TIMM50
uniprot id: A0A8B7H1Q2
uniprot id: A0A8B7WVF5
uniprot id: A0A8C5VI57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM50 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Mitochondrion inner membrane

30608:PIH1D1
gene id: 30608:PIH1D1
uniprot id: A0A8B7FM65
uniprot id: A0A8B7FNA0
names: Similarity
messages: Belongs to the PIH1 family.

30608:AWAT2
gene id: 30608:AWAT2
uniprot id: A0A8B7EBM5
uniprot id: A0A8B7WZM8
uniprot id: A0A8C5V3J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane

30608:HAO1
gene id: 30608:HAO1
uniprot id: A0A8C5UN57
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

30608:FAM198B
gene id: 30608:FAM198B
uniprot id: A0A8C5VKZ4
names: Similarity
messages: Belongs to the GASK family.

30608:LOC105870078
gene id: 30608:LOC105870078
uniprot id: A0A8B7G6J5
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

30608:LOC105861324
gene id: 30608:LOC105861324
uniprot id: A0A8B7F459
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105867374
gene id: 30608:LOC105867374
uniprot id: A0A8B7FV70
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:SPR
gene id: 30608:SPR
uniprot id: A0A8B7FBX8
names: Similarity
messages: Belongs to the sepiapterin reductase family.

30608:SULT1E1
gene id: 30608:SULT1E1
uniprot id: A0A8B7HTN1
uniprot id: A0A8C5YFE3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

30608:NOP58
gene id: 30608:NOP58
uniprot id: A0A8B7EIF4
uniprot id: A0A8B7EIF8
uniprot id: A0A8B7EIT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus
messages: nucleoplasm

30608:OS9
gene id: 30608:OS9
uniprot id: A0A8B7H7Q4
uniprot id: A0A8B7H7Q5
uniprot id: A0A8B7H7Q6
uniprot id: A0A8B7HAA3
uniprot id: A0A8B7X5T0
uniprot id: A0A8B7X5T5
uniprot id: A0A8B7X5T6
uniprot id: A0A8B7X6F4
uniprot id: A0A8B7X7J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OS-9 family.
messages: Endoplasmic reticulum lumen
messages: Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation.

30608:ACOT8
gene id: 30608:ACOT8
uniprot id: A0A8B7ET75
uniprot id: A0A8B7EV15
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

30608:LOC105861075
gene id: 30608:LOC105861075
uniprot id: A0A8C5W8G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

30608:FAM221A
gene id: 30608:FAM221A
uniprot id: A0A8B7GYM2
uniprot id: A0A8B7GYP1
uniprot id: A0A8C5Y2B6
names: Similarity
messages: Belongs to the FAM221 family.

30608:TNKS
gene id: 30608:TNKS
uniprot id: A0A8B7EKH4
uniprot id: A0A8C5Y6B2
names: Similarity
messages: Belongs to the ARTD/PARP family.

30608:LOC105868502
gene id: 30608:LOC105868502
uniprot id: A0A8B7FZI3
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:LOC105862433
gene id: 30608:LOC105862433
uniprot id: A0A8B7F892
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105865819
gene id: 30608:LOC105865819
uniprot id: A0A8B7FN54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SLC7A11
gene id: 30608:SLC7A11
uniprot id: A0A8C5USL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Cell membrane
messages: Membrane

30608:SMARCA2
gene id: 30608:SMARCA2
uniprot id: A0A8B7XAQ7
uniprot id: A0A8B7XAQ8
uniprot id: A0A8B7XCX1
uniprot id: A0A8B7XCX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

30608:ICAM4
gene id: 30608:ICAM4
uniprot id: A0A8B7WWJ7
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105867072
gene id: 30608:LOC105867072
uniprot id: A0A8C5XL98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CISD protein family. CISD2 subfamily.
messages: Binds 1 [2Fe-2S] cluster.
messages: Endoplasmic reticulum membrane
messages: Homodimer.
messages: Mitochondrion outer membrane
messages: Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy.

30608:COQ9
gene id: 30608:COQ9
uniprot id: A0A8B7FF00
uniprot id: A0A8B7WSY9
uniprot id: A0A8C5XJF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

30608:LOC105885239
gene id: 30608:LOC105885239
uniprot id: A0A8B7I5W0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:RAD51D
gene id: 30608:RAD51D
uniprot id: A0A8B7I2B8
uniprot id: A0A8B7I532
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus

30608:BCO2
gene id: 30608:BCO2
uniprot id: A0A8B7FA93
uniprot id: A0A8B7FA98
uniprot id: A0A8B7FAA0
uniprot id: A0A8B7FAA6
uniprot id: A0A8B7FAB1
uniprot id: A0A8B7FAG0
uniprot id: A0A8B7FAW6
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

30608:MRPS26
gene id: 30608:MRPS26
uniprot id: A0A8B7FNV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS26 family.
messages: Mitochondrion

30608:BCL9L
gene id: 30608:BCL9L
uniprot id: A0A8B7GZA4
uniprot id: A0A8B7GZB0
uniprot id: A0A8B7GZF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

30608:ZDHHC18
gene id: 30608:ZDHHC18
uniprot id: A0A8B7WLX5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

30608:PLBD1
gene id: 30608:PLBD1
uniprot id: A0A8C5V330
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

30608:SMIM14
gene id: 30608:SMIM14
uniprot id: A0A8C5VL16
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

30608:PGK1
gene id: 30608:PGK1
uniprot id: A0A8B7FPJ1
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

30608:RIF1
gene id: 30608:RIF1
uniprot id: A0A8B7HEJ2
uniprot id: A0A8C5Y6Z6
uniprot id: A0A8C5Y997
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

30608:PEPD
gene id: 30608:PEPD
uniprot id: A0A8B7H2Z3
names: Similarity
messages: Belongs to the peptidase M24B family.

30608:TRABD2A
gene id: 30608:TRABD2A
uniprot id: A0A8B7H351
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

30608:SMAD9
gene id: 30608:SMAD9
uniprot id: A0A8B7F6V5
uniprot id: A0A8B7XF72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

30608:LSM2
gene id: 30608:LSM2
uniprot id: A0A8B7X5V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

30608:LOC105861320
gene id: 30608:LOC105861320
uniprot id: A0A8B7F457
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TXNDC8
gene id: 30608:TXNDC8
uniprot id: A0A8B7XDC9
names: Similarity
messages: Belongs to the thioredoxin family.

30608:HKDC1
gene id: 30608:HKDC1
uniprot id: A0A8B7G7R1
uniprot id: A0A8C5XEG0
names: Similarity
messages: Belongs to the hexokinase family.

30608:KIAA2013
gene id: 30608:KIAA2013
uniprot id: A0A8B7HS70
uniprot id: A0A8B7HS86
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105863279
gene id: 30608:LOC105863279
uniprot id: A0A8B7FBW1
uniprot id: A0A8B7FBW9
uniprot id: A0A8B7FBX3
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:LOC105876646
gene id: 30608:LOC105876646
uniprot id: A0A8B7X3X8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:C8H2orf88
gene id: 30608:C8H2orf88
uniprot id: A0A8B7H9K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small membrane AKAP family.
messages: Cell membrane
messages: Membrane

30608:CCDC85A
gene id: 30608:CCDC85A
uniprot id: A0A8B7H9D1
uniprot id: A0A8B7H9D7
uniprot id: A0A8B7H9D9
uniprot id: A0A8B7H9E0
uniprot id: A0A8B7HC60
uniprot id: A0A8B7X225
uniprot id: A0A8C5XUU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

30608:L3MBTL1
gene id: 30608:L3MBTL1
uniprot id: A0A8B7HH70
names: Subcellular Location Annotation
messages: Nucleus

30608:TAS2R42
gene id: 30608:TAS2R42
uniprot id: A0A8B7X6D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

30608:FAM83B
gene id: 30608:FAM83B
uniprot id: A0A8C5W043
names: Similarity
messages: Belongs to the FAM83 family.

30608:NR0B2
gene id: 30608:NR0B2
uniprot id: A0A8B7FD17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

30608:MRS2
gene id: 30608:MRS2
uniprot id: A0A8B7FKL4
uniprot id: A0A8C5XEM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane

30608:SGCB
gene id: 30608:SGCB
uniprot id: A0A8B7GMM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: Cross-link to form 2 major subcomplexes: one consisting of SGCB, SGCD and SGCG and the other consisting of SGCB and SGCD. The association between SGCB and SGCG is particularly strong while SGCA is loosely associated with the other sarcoglycans.
messages: cytoskeleton
messages: sarcolemma

30608:DIABLO
gene id: 30608:DIABLO
uniprot id: A0A8B7HJW4
uniprot id: A0A8B7HMF6
names: Subcellular Location Annotation
messages: Mitochondrion

30608:CDV3
gene id: 30608:CDV3
uniprot id: A0A8B7GHK3
uniprot id: A0A8B7GHK7
uniprot id: A0A8B7GHY9
uniprot id: A0A8B7GI92
uniprot id: A0A8B7GI96
uniprot id: A0A8B7GIA1
uniprot id: A0A8B7GIH2
names: Similarity
messages: Belongs to the CDV3 family.

30608:LOC105856978
gene id: 30608:LOC105856978
uniprot id: A0A8B7EJ27
uniprot id: A0A8B7EL42
uniprot id: A0A8C5VB74
uniprot id: M1ZMS2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

30608:LOC105879234
gene id: 30608:LOC105879234
uniprot id: A0A8B7HD05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NDUFC2
gene id: 30608:NDUFC2
uniprot id: A0A8B7X3C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFC2 subunit family.
messages: Mitochondrion inner membrane

30608:AIMP2
gene id: 30608:AIMP2
uniprot id: A0A8B7FXW6
uniprot id: A0A8B7FYZ5
uniprot id: A0A8C5W900
uniprot id: A0A8C5XDW7
names: Subcellular Location Annotation
messages: Nucleus
messages: cytosol

30608:LOC105879968
gene id: 30608:LOC105879968
uniprot id: A0A8B7HIU7
uniprot id: A0A8B7X4L1
names: Function
names: Similarity
messages: Belongs to the SAA family.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.

30608:SLC5A12
gene id: 30608:SLC5A12
uniprot id: A0A8B7EXJ9
uniprot id: A0A8B7EZF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

30608:LOC105878781
gene id: 30608:LOC105878781
uniprot id: A0A8B7HB52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM15 family.
messages: Membrane

30608:ATP1B3
gene id: 30608:ATP1B3
uniprot id: A0A8B7G691
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

30608:SLC50A1
gene id: 30608:SLC50A1
uniprot id: A0A8B7GKF3
uniprot id: A0A8B7GKQ6
uniprot id: A0A8C5YE39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWEET sugar transporter family.
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates sugar transport across membranes.
messages: Membrane

30608:PXN
gene id: 30608:PXN
uniprot id: A0A8B7FSX4
uniprot id: A0A8B7WSZ6
uniprot id: A0A8B7WSZ8
uniprot id: A0A8B7WT01
uniprot id: A0A8B7WT04
uniprot id: A0A8B7WT41
uniprot id: A0A8B7WTA1
uniprot id: A0A8B7WTB0
uniprot id: A0A8B7WUJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paxillin family.
messages: cytoskeleton

30608:DMBX1
gene id: 30608:DMBX1
uniprot id: A0A8B7H585
uniprot id: A0A8C5XVP2
names: Subcellular Location Annotation
messages: Nucleus

30608:DDX43
gene id: 30608:DDX43
uniprot id: A0A8B7I0W1
uniprot id: A0A8B7I2Z6
names: Similarity
messages: Belongs to the DEAD box helicase family.

30608:ACE2
gene id: 30608:ACE2
uniprot id: A0A8B7WZF6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Secreted
messages: cilium

30608:LOC105879210
gene id: 30608:LOC105879210
uniprot id: A0A8B7WN47
names: Cofactor
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Binds 1 Fe cation per subunit.

30608:LOC105880627
gene id: 30608:LOC105880627
uniprot id: A0A8C5XZL0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

30608:LOC105867758
gene id: 30608:LOC105867758
uniprot id: A0A8B7FX26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:DKK4
gene id: 30608:DKK4
uniprot id: A0A8B7WRV7
uniprot id: A0A8B7WTB9
uniprot id: A0A8C5YE62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

30608:LPCAT3
gene id: 30608:LPCAT3
uniprot id: A0A8B7G1J1
names: Subcellular Location Annotation
messages: Membrane

30608:MLH1
gene id: 30608:MLH1
uniprot id: A0A8C5YH13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

30608:TBX4
gene id: 30608:TBX4
uniprot id: A0A8B7GZK5
uniprot id: A0A8B7H1A5
uniprot id: A0A8B7WMQ1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

30608:POU4F3
gene id: 30608:POU4F3
uniprot id: A0A8B7H0T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

30608:VAX2
gene id: 30608:VAX2
uniprot id: A0A8C5Y3L9
names: Subcellular Location Annotation
messages: Nucleus

30608:TAF6
gene id: 30608:TAF6
uniprot id: A0A8B7FYA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

30608:NAPG
gene id: 30608:NAPG
uniprot id: A0A8B7F1I5
uniprot id: A0A8C5XYP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

30608:PIEZO2
gene id: 30608:PIEZO2
uniprot id: A0A8B7F1E4
uniprot id: A0A8B7F1E8
uniprot id: A0A8B7F1F0
uniprot id: A0A8B7F352
uniprot id: A0A8B7F3L9
uniprot id: A0A8B7F3M1
uniprot id: A0A8C5VY06
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIEZO (TC 1.A.75) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:THBS3
gene id: 30608:THBS3
uniprot id: A0A8C5VRR2
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:SIN3B
gene id: 30608:SIN3B
uniprot id: A0A8C5XHY3
names: Subcellular Location Annotation
messages: Nucleus

30608:SLC16A14
gene id: 30608:SLC16A14
uniprot id: A0A8B7F9T1
uniprot id: A0A8B7F9T5
uniprot id: A0A8B7FAC3
names: Subcellular Location Annotation
messages: Membrane

30608:DESI2
gene id: 30608:DESI2
uniprot id: A0A8B7FFP4
names: Similarity
messages: Belongs to the DeSI family.

30608:LOC105860069
gene id: 30608:LOC105860069
uniprot id: A0A8B7EX54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 54 family.
messages: Golgi apparatus membrane

30608:LOC105882998
gene id: 30608:LOC105882998
uniprot id: A0A8B7HVG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

30608:SLC25A6
gene id: 30608:SLC25A6
uniprot id: A0A8C5UP24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

30608:GOLPH3L
gene id: 30608:GOLPH3L
uniprot id: A0A8C5W2K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

30608:PLPPR1
gene id: 30608:PLPPR1
uniprot id: A0A8C5V2N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

30608:RPL37
gene id: 30608:RPL37
uniprot id: A0A8B7H996
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

30608:LOC105875026
gene id: 30608:LOC105875026
uniprot id: A0A8B7GU23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

30608:PPP1R16A
gene id: 30608:PPP1R16A
uniprot id: A0A8B7G0M8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:LOC105880624
gene id: 30608:LOC105880624
uniprot id: A0A8B7HJU6
names: Similarity
messages: Belongs to the peptidase C14A family.

30608:LOC105857695
gene id: 30608:LOC105857695
uniprot id: A0A8C6EKK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

30608:NDUFS7
gene id: 30608:NDUFS7
uniprot id: A0A8B7F0F2
uniprot id: A0A8B7F0F3
uniprot id: A0A8B7F2R9
uniprot id: A0A8C5VR66
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

30608:THAP1
gene id: 30608:THAP1
uniprot id: A0A8B7H8A7
uniprot id: A0A8C5XWW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: Interacts with PAWR. Component of a THAP1/THAP3-HCFC1-OGT complex that contains, either THAP1 or THAP3, HCFC1 and OGT. Interacts with OGT. Interacts (via the HBM) with HCFC1 (via the Kelch-repeat domain); the interaction recruits HCFC1 to the RRM1 promoter.
messages: nucleoplasm

30608:NCAPD2
gene id: 30608:NCAPD2
uniprot id: A0A8B7G1M8
uniprot id: A0A8C5USF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND1 (condensin subunit 1) family.
messages: Chromosome
messages: Nucleus
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

30608:ESD
gene id: 30608:ESD
uniprot id: A0A8B7HKS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the esterase D family.
messages: Cytoplasmic vesicle
messages: Serine hydrolase involved in the detoxification of formaldehyde.

30608:MRFAP1
gene id: 30608:MRFAP1
uniprot id: A0A8B7F5X7
names: Similarity
messages: Belongs to the MORF4 family-associated protein family.

30608:LMBR1
gene id: 30608:LMBR1
uniprot id: A0A8B7HUH4
uniprot id: A0A8B7HUH8
uniprot id: A0A8B7HWL9
uniprot id: A0A8C5XQR9
names: Similarity
messages: Belongs to the LIMR family.

30608:LOC105874070
gene id: 30608:LOC105874070
uniprot id: A0A8B7GPX1
names: Similarity
messages: Belongs to the CD225/Dispanin family.

30608:UBE2G2
gene id: 30608:UBE2G2
uniprot id: A0A8B7HEN2
uniprot id: A0A8B7HEQ2
uniprot id: A0A8B7HF15
uniprot id: A0A8C6EK79
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:BET1L
gene id: 30608:BET1L
uniprot id: A0A8C5VDX5
names: Subcellular Location Annotation
messages: Membrane

30608:SLC9C1
gene id: 30608:SLC9C1
uniprot id: A0A8B7HXK0
uniprot id: A0A8B7HXM0
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

30608:CRYBA1
gene id: 30608:CRYBA1
uniprot id: A0A8B7EPE7
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

30608:LOC105881499
gene id: 30608:LOC105881499
uniprot id: A0A8C5V1X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-defensin family.
messages: Secreted

30608:SEMA3G
gene id: 30608:SEMA3G
uniprot id: A0A8B7GU71
uniprot id: A0A8C5VNR3
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LIG1
gene id: 30608:LIG1
uniprot id: A0A8B7G330
uniprot id: A0A8C6EK52
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

30608:YWHAZ
gene id: 30608:YWHAZ
uniprot id: A0A8B7G6A9
names: Similarity
messages: Belongs to the 14-3-3 family.

30608:GCGR
gene id: 30608:GCGR
uniprot id: A0A8B7I5F2
uniprot id: A0A8B7WMJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

30608:CRYBB2
gene id: 30608:CRYBB2
uniprot id: A0A8B7FSF0
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

30608:FLNC
gene id: 30608:FLNC
uniprot id: A0A8B7I1U4
uniprot id: A0A8B7I1U5
names: Similarity
messages: Belongs to the filamin family.

30608:CHMP4B
gene id: 30608:CHMP4B
uniprot id: A0A8C5YAI6
names: Similarity
messages: Belongs to the SNF7 family.

30608:RABAC1
gene id: 30608:RABAC1
uniprot id: A0A8C5W3S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

30608:LOC105862269
gene id: 30608:LOC105862269
uniprot id: A0A8B7F7P4
names: Subcellular Location Annotation
messages: Membrane

30608:ADRB2
gene id: 30608:ADRB2
uniprot id: A0A8B7WWW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily.
messages: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
messages: Cell membrane
messages: Early endosome
messages: Golgi apparatus
messages: Membrane

30608:PKD1L3
gene id: 30608:PKD1L3
uniprot id: A0A8B7ETQ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:FAM53C
gene id: 30608:FAM53C
uniprot id: A0A8C5XIG9
names: Similarity
messages: Belongs to the FAM53 family.

30608:LTBP1
gene id: 30608:LTBP1
uniprot id: A0A8B7HZY0
uniprot id: A0A8B7HZY4
uniprot id: A0A8B7HZY6
uniprot id: A0A8B7HZZ1
uniprot id: A0A8B7HZZ7
uniprot id: A0A8B7I223
uniprot id: A0A8B7I227
uniprot id: A0A8B7I2N5
uniprot id: A0A8C5Y0W7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:EDNRA
gene id: 30608:EDNRA
uniprot id: A0A8C5VBP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

30608:NIPAL2
gene id: 30608:NIPAL2
uniprot id: A0A8B7G5E8
uniprot id: A0A8B7G5J2
uniprot id: A0A8B7G671
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

30608:NKX1-2
gene id: 30608:NKX1-2
uniprot id: A0A8C5Y268
names: Subcellular Location Annotation
messages: Nucleus

30608:FXYD3
gene id: 30608:FXYD3
uniprot id: A0A8B7H2S9
names: Similarity
messages: Belongs to the FXYD family.

30608:LOC105862116
gene id: 30608:LOC105862116
uniprot id: A0A8B7F705
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LDB1
gene id: 30608:LDB1
uniprot id: A0A8B7GPI4
uniprot id: A0A8B7GPS9
uniprot id: A0A8B7GQ15
uniprot id: A0A8B7GQ29
uniprot id: A0A8B7GR15
uniprot id: A0A8B7GR27
names: Similarity
messages: Belongs to the LDB family.

30608:CDC42EP2
gene id: 30608:CDC42EP2
uniprot id: A0A8B7H9Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

30608:MKI67
gene id: 30608:MKI67
uniprot id: A0A8B7WLB4
names: Subcellular Location Annotation
messages: Nucleus

30608:SPIC
gene id: 30608:SPIC
uniprot id: A0A8B7GX02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

30608:MIXL1
gene id: 30608:MIXL1
uniprot id: A0A8B7FEC2
names: Subcellular Location Annotation
messages: Nucleus

30608:GLG1
gene id: 30608:GLG1
uniprot id: A0A8B7GWW8
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Golgi outpost
messages: Membrane
messages: microtubule organizing center

30608:MURC
gene id: 30608:MURC
uniprot id: A0A8B7GNF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

30608:TET1
gene id: 30608:TET1
uniprot id: A0A8B7G737
uniprot id: A0A8B7G744
uniprot id: A0A8B7G791
uniprot id: A0A8B7G7S8
uniprot id: A0A8C5YG92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Chromosome
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

30608:MYO5A
gene id: 30608:MYO5A
uniprot id: A0A8B7G8Y7
uniprot id: A0A8B7G8Z0
uniprot id: A0A8B7G8Z1
uniprot id: A0A8B7G9L8
uniprot id: A0A8B7GA28
uniprot id: A0A8B7GA32
uniprot id: A0A8B7X343
uniprot id: A0A8C5V174
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:ELOVL2
gene id: 30608:ELOVL2
uniprot id: A0A8B7FKF3
uniprot id: A0A8B7FLR3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL2 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

30608:GLYATL3
gene id: 30608:GLYATL3
uniprot id: A0A8B7G3Z4
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

30608:LOC105861274
gene id: 30608:LOC105861274
uniprot id: A0A8C5VYA0
names: Subcellular Location Annotation
messages: Membrane

30608:SATB1
gene id: 30608:SATB1
uniprot id: A0A8B7FQH2
uniprot id: A0A8B7FQP1
uniprot id: A0A8B7FRN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

30608:BCCIP
gene id: 30608:BCCIP
uniprot id: A0A8B7HHV7
uniprot id: A0A8B7HHX9
uniprot id: A0A8C5XFR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCP1 family.
messages: May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ).
messages: Nucleus
messages: spindle pole

30608:HYAL1
gene id: 30608:HYAL1
uniprot id: A0A8C5V4S7
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

30608:ASIC5
gene id: 30608:ASIC5
uniprot id: A0A8B7HQB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

30608:CMC4
gene id: 30608:CMC4
uniprot id: A0A8B7FHR3
uniprot id: A0A8C6EIU5
names: Similarity
messages: Belongs to the CMC4 family.

30608:PAX5
gene id: 30608:PAX5
uniprot id: A0A8B7GNA2
uniprot id: A0A8B7GNA6
uniprot id: A0A8B7GNA7
uniprot id: A0A8B7GNL0
uniprot id: A0A8B7GNU7
uniprot id: A0A8B7GPN5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with KDM5B.
messages: Nucleus
messages: Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs.

30608:LOC105881539
gene id: 30608:LOC105881539
uniprot id: A0A8B7HM59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

30608:AQP6
gene id: 30608:AQP6
uniprot id: A0A8B7G576
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

30608:SCFD1
gene id: 30608:SCFD1
uniprot id: A0A8B7GYZ6
uniprot id: A0A8B7H0W5
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

30608:EHD3
gene id: 30608:EHD3
uniprot id: A0A8B7I2L0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

30608:LCN10
gene id: 30608:LCN10
uniprot id: A0A8B7HSA5
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

30608:SHROOM1
gene id: 30608:SHROOM1
uniprot id: A0A8B7G5S9
uniprot id: A0A8B7G5W7
uniprot id: A0A8B7G727
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

30608:KCNC2
gene id: 30608:KCNC2
uniprot id: A0A8B7FDX0
uniprot id: A0A8B7FDY3
uniprot id: A0A8B7FDZ3
uniprot id: A0A8B7FE38
uniprot id: A0A8B7FE46
uniprot id: A0A8B7FEU1
uniprot id: A0A8B7FEU7
uniprot id: A0A8C5XHL3
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105884518
gene id: 30608:LOC105884518
uniprot id: A0A8B7I2W1
uniprot id: A0A8B7X8W6
uniprot id: A0A8B7XAJ4
names: Similarity
messages: Belongs to the TTC39 family.

30608:TUBD1
gene id: 30608:TUBD1
uniprot id: A0A8B7GTB6
uniprot id: A0A8B7GU77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Nucleus
messages: centriole
messages: cilium

30608:OSBPL3
gene id: 30608:OSBPL3
uniprot id: A0A8B7GYQ0
names: Similarity
messages: Belongs to the OSBP family.

30608:LOC105856163
gene id: 30608:LOC105856163
uniprot id: A0A8B7X310
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

30608:GRIK2
gene id: 30608:GRIK2
uniprot id: A0A8B7X553
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

30608:FXYD6
gene id: 30608:FXYD6
uniprot id: A0A8B7GZE8
uniprot id: A0A8B7GZJ7
uniprot id: A0A8C5Y8K7
names: Caution
names: Similarity
messages: Belongs to the FXYD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:TMOD1
gene id: 30608:TMOD1
uniprot id: A0A8B7GNE7
names: Subcellular Location Annotation
messages: cytoskeleton

30608:ZDHHC21
gene id: 30608:ZDHHC21
uniprot id: A0A8C5XHW3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

30608:FAM166A
gene id: 30608:FAM166A
uniprot id: A0A8B7HQ35
uniprot id: A0A8B7HQ36
uniprot id: A0A8B7HSH3
names: Similarity
messages: Belongs to the CIMIP2 family.

30608:LOC105864772
gene id: 30608:LOC105864772
uniprot id: A0A8B7X392
names: Subcellular Location Annotation
messages: Membrane

30608:OSBPL1A
gene id: 30608:OSBPL1A
uniprot id: A0A8B7F0U4
uniprot id: A0A8B7F0U6
uniprot id: A0A8B7F0U7
uniprot id: A0A8B7F0U9
uniprot id: A0A8B7F0V2
uniprot id: A0A8B7F2L4
uniprot id: A0A8C5XEE8
names: Similarity
messages: Belongs to the OSBP family.

30608:STT3B
gene id: 30608:STT3B
uniprot id: A0A8B7GNF0
uniprot id: A0A8B7GNQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

30608:PCSK6
gene id: 30608:PCSK6
uniprot id: A0A8B7GBU2
names: Similarity
messages: Belongs to the peptidase S8 family.

30608:LOC105883577
gene id: 30608:LOC105883577
uniprot id: A0A8B7HY11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM187 family.
messages: Membrane

30608:MDC1
gene id: 30608:MDC1
uniprot id: A0A8B7X440
uniprot id: A0A8B7X441
uniprot id: A0A8B7X445
uniprot id: A0A8B7X4M9
uniprot id: A0A8B7X5T1
uniprot id: A0A8B7X5U1
names: Function
messages: Required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. May serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked by 'Ser-139' phosphorylation of histone H2AX. Also required for downstream events subsequent to the recruitment of these proteins. These include phosphorylation and activation of the ATM, CHEK1 and CHEK2 kinases, and stabilization of TP53 and apoptosis. ATM and CHEK2 may also be activated independently by a parallel pathway mediated by TP53BP1.

30608:GJA3
gene id: 30608:GJA3
uniprot id: A0A8B7HDW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

30608:NOL8
gene id: 30608:NOL8
uniprot id: A0A8B7F4I7
uniprot id: A0A8B7F4J0
names: Subcellular Location Annotation
messages: nucleolus

30608:VSX1
gene id: 30608:VSX1
uniprot id: A0A8B7EZS8
uniprot id: A0A8B7EZT0
uniprot id: A0A8B7EZU1
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105866530
gene id: 30608:LOC105866530
uniprot id: A0A8B7FQV3
names: Subcellular Location Annotation
messages: Membrane

30608:SPTSSA
gene id: 30608:SPTSSA
uniprot id: A0A8C5YDK2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:TMEM135
gene id: 30608:TMEM135
uniprot id: A0A8B7F0L9
uniprot id: A0A8C5VFY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM135 family.
messages: Membrane

30608:FGF18
gene id: 30608:FGF18
uniprot id: A0A8C5UZU5
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

30608:ZHX3
gene id: 30608:ZHX3
uniprot id: A0A8B7FMT8
uniprot id: A0A8B7FN33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

30608:AQP8
gene id: 30608:AQP8
uniprot id: A0A8B7HFE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

30608:MPV17L2
gene id: 30608:MPV17L2
uniprot id: A0A8B7EAH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

30608:GPR20
gene id: 30608:GPR20
uniprot id: A0A8B7FFZ2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:CWC25
gene id: 30608:CWC25
uniprot id: A0A8C5US54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWC25 family.
messages: Nucleus

30608:LOC105881317
gene id: 30608:LOC105881317
uniprot id: A0A8B7WWF7
uniprot id: A0A8B7WWS4
uniprot id: A0A8B7WX74
uniprot id: A0A8B7WY68
names: Similarity
messages: Belongs to the SPATA31 family.

30608:LOC105862126
gene id: 30608:LOC105862126
uniprot id: A0A8B7F711
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:IMMP2L
gene id: 30608:IMMP2L
uniprot id: A0A8B7XC19
uniprot id: A0A8C5XY60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family. IMP2 subfamily.
messages: Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Membrane
messages: Mitochondrion inner membrane

30608:LAMP1
gene id: 30608:LAMP1
uniprot id: A0A8B7GF42
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

30608:TMEM19
gene id: 30608:TMEM19
uniprot id: A0A8B7EI47
uniprot id: A0A8B7EI55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

30608:LOC105859571
gene id: 30608:LOC105859571
uniprot id: A0A8B7EWF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105862797
gene id: 30608:LOC105862797
uniprot id: A0A8B7F9R6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:SNX32
gene id: 30608:SNX32
uniprot id: A0A8B7HA70
uniprot id: A0A8B7HA71
uniprot id: A0A8B7X2L9
uniprot id: A0A8B7X2M0
uniprot id: A0A8B7X4D1
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

30608:AMBP
gene id: 30608:AMBP
uniprot id: A0A8B7GMI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Endoplasmic reticulum
messages: In the N-terminal section; belongs to the calycin superfamily. Lipocalin family.
messages: Kunitz-type serine protease inhibitor. Has high catalytic efficiency for F10/blood coagulation factor Xa and may act as an anticoagulant by inhibiting prothrombin activation. Inhibits trypsin and mast cell CMA1/chymase and tryptase proteases.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Monomer. Also occurs as a complex with tryptase in mast cells.
messages: Nucleus membrane
messages: cytosol
messages: extracellular matrix

30608:ALKBH8
gene id: 30608:ALKBH8
uniprot id: A0A8B7GZK9
uniprot id: A0A8B7GZL0
uniprot id: A0A8B7H1I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkB family.
messages: Cytoplasm

30608:SNRPD3
gene id: 30608:SNRPD3
uniprot id: A0A8C5VRU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing.
messages: cytosol

30608:CROT
gene id: 30608:CROT
uniprot id: A0A8B7HG53
uniprot id: A0A8C5ULL9
uniprot id: A0A8C6EKC4
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

30608:CBLC
gene id: 30608:CBLC
uniprot id: A0A8B7G4M5
names: Domain
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

30608:LOC105878897
gene id: 30608:LOC105878897
uniprot id: A0A8B7HBI3
uniprot id: A0A8B7HBI5
uniprot id: A0A8B7HBI7
uniprot id: A0A8B7HE70
uniprot id: A0A8C5XRZ1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:SFPQ
gene id: 30608:SFPQ
uniprot id: A0A8B7GDI4
uniprot id: A0A8C5VWT9
names: Subcellular Location Annotation
messages: Nucleus speckle

30608:BABAM1
gene id: 30608:BABAM1
uniprot id: A0A8B7WZ58
uniprot id: A0A8C5VNV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BABAM1 family.
messages: Nucleus

30608:SLC30A5
gene id: 30608:SLC30A5
uniprot id: A0A8B7HL86
uniprot id: A0A8B7HLA7
uniprot id: A0A8C5Y5X3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Homooligomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: trans-Golgi network membrane

30608:PPP2R2C
gene id: 30608:PPP2R2C
uniprot id: A0A8B7F5V6
uniprot id: A0A8B7F5W1
uniprot id: A0A8B7F5W7
uniprot id: A0A8B7F5Y9
uniprot id: A0A8B7F5Z4
uniprot id: A0A8C5VNA9
uniprot id: A0A8C5XT30
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

30608:MC3R
gene id: 30608:MC3R
uniprot id: A0A8B7F7V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane

30608:LOC105858002
gene id: 30608:LOC105858002
uniprot id: A0A8B7EN12
names: Similarity
messages: Belongs to the SPATA31 family.

30608:LMLN
gene id: 30608:LMLN
uniprot id: A0A8B7HFL0
uniprot id: A0A8B7HG66
uniprot id: A0A8B7HI95
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M8 family.
messages: Binds 1 zinc ion per subunit.

30608:THAP10
gene id: 30608:THAP10
uniprot id: A0A8C5VFE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: Interacts with PAWR. Component of a THAP1/THAP3-HCFC1-OGT complex that contains, either THAP1 or THAP3, HCFC1 and OGT. Interacts with OGT. Interacts (via the HBM) with HCFC1 (via the Kelch-repeat domain); the interaction recruits HCFC1 to the RRM1 promoter.
messages: nucleoplasm

30608:CIAO1
gene id: 30608:CIAO1
uniprot id: A0A8B7HW57
uniprot id: A0A8B7HW67
uniprot id: A0A8B7HYJ0
uniprot id: A0A8C5Y0X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat CIA1 family.
messages: Component of the CIA complex. Component of the MMXD complex, which includes CIAO1, ERCC2, FAM96B, MMS19 and SLC25A5. Interacts with WT1. Interacts with FAM96A.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.

30608:AKIRIN2
gene id: 30608:AKIRIN2
uniprot id: A0A8C5Y4K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

30608:LOC105885233
gene id: 30608:LOC105885233
uniprot id: A0A8B7I3U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

30608:SLC39A12
gene id: 30608:SLC39A12
uniprot id: A0A8B7WWF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

30608:BRS3
gene id: 30608:BRS3
uniprot id: A0A8C5XSY6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with C6orf89.
messages: Membrane

30608:QTRT1
gene id: 30608:QTRT1
uniprot id: A0A8C5XQN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.
messages: Mitochondrion outer membrane

30608:VHL
gene id: 30608:VHL
uniprot id: A0A8B7G203
names: Similarity
messages: Belongs to the VHL family.

30608:TMEM35B
gene id: 30608:TMEM35B
uniprot id: A0A8B7GDJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

30608:SENP3
gene id: 30608:SENP3
uniprot id: A0A8B7WNF5
uniprot id: A0A8C5VPV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C48 family.
messages: nucleolus

30608:LOC109730286
gene id: 30608:LOC109730286
uniprot id: A0A8B7WZY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

30608:DDX28
gene id: 30608:DDX28
uniprot id: A0A8B7ERP9
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

30608:LCAT
gene id: 30608:LCAT
uniprot id: A0A8B7ETS6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

30608:SPTY2D1
gene id: 30608:SPTY2D1
uniprot id: A0A8C5VAT7
names: Similarity
messages: Belongs to the SPT2 family.

30608:LOC105872179
gene id: 30608:LOC105872179
uniprot id: A0A8C5V147
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:HSPB9
gene id: 30608:HSPB9
uniprot id: A0A8B7EU24
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

30608:FAT3
gene id: 30608:FAT3
uniprot id: A0A8B7X3Y2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:ELOVL6
gene id: 30608:ELOVL6
uniprot id: A0A8B7GFX2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL6 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.

30608:EPS8L3
gene id: 30608:EPS8L3
uniprot id: A0A8B7FFD6
names: Similarity
messages: Belongs to the EPS8 family.

30608:SLC25A25
gene id: 30608:SLC25A25
uniprot id: A0A8B7GVI9
uniprot id: A0A8B7GVJ6
uniprot id: A0A8B7GVP7
uniprot id: A0A8B7GXC0
uniprot id: A0A8C5VT45
uniprot id: A0A8C5W957
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

30608:SUPT3H
gene id: 30608:SUPT3H
uniprot id: A0A8B7EUA5
uniprot id: A0A8B7EUA7
uniprot id: A0A8B7EUB1
uniprot id: A0A8B7EW99
uniprot id: A0A8C5UZG7
names: Subcellular Location Annotation
messages: Nucleus

30608:YWHAB
gene id: 30608:YWHAB
uniprot id: A0A8C5VCL8
names: Similarity
messages: Belongs to the 14-3-3 family.

30608:KDELC2
gene id: 30608:KDELC2
uniprot id: A0A8B7H1L8
names: Similarity
messages: Belongs to the KDELC family.

30608:CYGB
gene id: 30608:CYGB
uniprot id: A0A8B7HBZ9
uniprot id: A0A8C5WAN4
names: Similarity
messages: Belongs to the globin family.

30608:CNTNAP2
gene id: 30608:CNTNAP2
uniprot id: A0A8B7GKZ2
uniprot id: A0A8B7GM67
uniprot id: A0A8B7GM73
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: paranodal septate junction

30608:DDOST
gene id: 30608:DDOST
uniprot id: A0A8B7HY18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

30608:RTEL1
gene id: 30608:RTEL1
uniprot id: A0A8B7GXT2
uniprot id: A0A8B7GXT7
uniprot id: A0A8B7GXX8
uniprot id: A0A8B7GZM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Interacts with TERF1. Interacts (via PIP-box) with PCNA; the interaction is direct and essential for suppressing telomere fragility. Interacts with MMS19; the interaction mediates the association of RTEL1 with the cytosolic iron-sulfur protein assembly (CIA) complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

30608:CFI
gene id: 30608:CFI
uniprot id: A0A8B7GGR3
uniprot id: A0A8C5YBH2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:PFDN2
gene id: 30608:PFDN2
uniprot id: A0A8C5V022
names: Function
names: Similarity
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

30608:CFHR1
gene id: 30608:CFHR1
uniprot id: A0A8B7EUB6
uniprot id: A0A8B7WWY5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:XPA
gene id: 30608:XPA
uniprot id: A0A8C5V6X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPA family.
messages: Nucleus

30608:ADPRH
gene id: 30608:ADPRH
uniprot id: A0A8B7HIQ0
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

30608:RNGTT
gene id: 30608:RNGTT
uniprot id: A0A8B7FDM8
uniprot id: A0A8B7FDN5
uniprot id: A0A8B7FEI9
uniprot id: A0A8C5Y1N8
uniprot id: A0A8C6EKR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.
messages: In the C-terminal section; belongs to the eukaryotic GTase family.
messages: In the N-terminal section; belongs to the non-receptor class of the protein-tyrosine phosphatase family.
messages: Nucleus

30608:DTX1
gene id: 30608:DTX1
uniprot id: A0A8B7WT85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

30608:LHFPL4
gene id: 30608:LHFPL4
uniprot id: A0A8C6EIU3
names: Subcellular Location Annotation
messages: Membrane

30608:MYO5C
gene id: 30608:MYO5C
uniprot id: A0A8B7G981
uniprot id: A0A8B7G9M3
uniprot id: A0A8B7GA34
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:MAP2K1
gene id: 30608:MAP2K1
uniprot id: A0A8B7FX99
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:ARL8A
gene id: 30608:ARL8A
uniprot id: A0A8C5W7E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: axon
messages: spindle

30608:ITGA6
gene id: 30608:ITGA6
uniprot id: A0A8B7HJ59
uniprot id: A0A8B7HK94
uniprot id: A0A8C6EHI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

30608:PIP
gene id: 30608:PIP
uniprot id: A0A8B7GLK2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PIP family.
messages: Monomer. Interacts with AZGP1.
messages: Secreted

30608:IL1F10
gene id: 30608:IL1F10
uniprot id: A0A8C5Y4N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

30608:MCM5
gene id: 30608:MCM5
uniprot id: A0A8B7HWI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

30608:SLC4A1
gene id: 30608:SLC4A1
uniprot id: A0A8B7HVP9
uniprot id: A0A8B7HVR1
uniprot id: A0A8C5XIC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

30608:EOGT
gene id: 30608:EOGT
uniprot id: A0A8B7WXN1
names: Similarity
messages: Belongs to the glycosyltransferase 61 family.

30608:SLC25A23
gene id: 30608:SLC25A23
uniprot id: A0A8B7G4N7
uniprot id: A0A8B7G4P2
uniprot id: A0A8B7G4P3
uniprot id: A0A8B7G4S5
uniprot id: A0A8B7G5H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

30608:LIN28B
gene id: 30608:LIN28B
uniprot id: A0A8B7FJF8
uniprot id: A0A8C5Y995
names: Similarity
messages: Belongs to the lin-28 family.

30608:PPM1A
gene id: 30608:PPM1A
uniprot id: A0A8B7H8U6
uniprot id: A0A8C5V723
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

30608:ASB18
gene id: 30608:ASB18
uniprot id: A0A8B7FMS7
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

30608:ATG4A
gene id: 30608:ATG4A
uniprot id: A0A8B7FCW3
uniprot id: A0A8C5XJY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

30608:KIF23
gene id: 30608:KIF23
uniprot id: A0A8B7GLA2
uniprot id: A0A8B7GLB1
uniprot id: A0A8B7GLV9
uniprot id: A0A8B7GLW4
uniprot id: A0A8B7GMJ8
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:CDYL2
gene id: 30608:CDYL2
uniprot id: A0A8B7F2C4
uniprot id: A0A8B7WTC9
names: Subcellular Location Annotation
messages: Nucleus

30608:PEX2
gene id: 30608:PEX2
uniprot id: A0A8B7EIZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Membrane
messages: Peroxisome membrane

30608:CEP290
gene id: 30608:CEP290
uniprot id: A0A8B7FVH3
uniprot id: A0A8B7FVH4
uniprot id: A0A8B7FVM9
uniprot id: A0A8B7FWF4
uniprot id: A0A8B7FWG2
uniprot id: A0A8B7FWG8
names: Subcellular Location Annotation
messages: cilium basal body

30608:KIF1BP
gene id: 30608:KIF1BP
uniprot id: A0A8C5XRH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KIF-binding protein family.
messages: cytoskeleton

30608:PIGZ
gene id: 30608:PIGZ
uniprot id: A0A8B7HFX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:PRPF18
gene id: 30608:PRPF18
uniprot id: A0A8B7EG11
uniprot id: A0A8C5V9L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

30608:SSH3
gene id: 30608:SSH3
uniprot id: A0A8B7FUW7
uniprot id: A0A8B7FVM2
uniprot id: A0A8B7FVR5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

30608:NTF4
gene id: 30608:NTF4
uniprot id: A0A8B7FM51
names: Similarity
messages: Belongs to the NGF-beta family.

30608:MTG1
gene id: 30608:MTG1
uniprot id: A0A8B7F3C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Mitochondrion inner membrane
messages: Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity. Displays mitochondrial GTPase activity.

30608:PEX12
gene id: 30608:PEX12
uniprot id: A0A8C5XTY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling.
messages: Membrane
messages: Peroxisome membrane

30608:VPS45
gene id: 30608:VPS45
uniprot id: A0A8B7WX18
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

30608:RNF20
gene id: 30608:RNF20
uniprot id: A0A8B7GMT6
uniprot id: A0A8B7GMU0
uniprot id: A0A8B7GN47
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BRE1 family.
messages: Component of the RNF20/40 complex (also known as BRE1 complex) probably composed of 2 copies of RNF20/BRE1A and 2 copies of RNF40/BRE1B. Interacts with UBE2E1/UBCH6.
messages: Nucleus

30608:KIF1C
gene id: 30608:KIF1C
uniprot id: A0A8B7HD49
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:SEPT4
gene id: 30608:SEPT4
uniprot id: A0A8B7GED9
uniprot id: A0A8B7GEK5
uniprot id: A0A8B7GEL1
uniprot id: A0A8B7GEQ2
uniprot id: A0A8B7GF80
uniprot id: A0A8B7GFN5
uniprot id: A0A8B7GFU9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

30608:TBX20
gene id: 30608:TBX20
uniprot id: A0A8C5Y2R9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

30608:LOC105867427
gene id: 30608:LOC105867427
uniprot id: A0A8B7FVG6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

30608:FUT1
gene id: 30608:FUT1
uniprot id: A0A8B7WU71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 11 family.
messages: Golgi stack membrane
messages: Membrane

30608:REEP3
gene id: 30608:REEP3
uniprot id: A0A8B7G799
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

30608:CASTOR2
gene id: 30608:CASTOR2
uniprot id: A0A8B7ERD3
names: Similarity
messages: Belongs to the GATS family.

30608:TSC22D4
gene id: 30608:TSC22D4
uniprot id: A0A8C5VW97
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

30608:LOC105883120
gene id: 30608:LOC105883120
uniprot id: A0A8B7XDI4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

30608:C12H5orf30
gene id: 30608:C12H5orf30
uniprot id: A0A8B7GYH0
uniprot id: A0A8B7XD35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UNC119-binding protein family.
messages: Cytoplasm
messages: cilium

30608:MTHFD1
gene id: 30608:MTHFD1
uniprot id: A0A8B7X1W9
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

30608:BICD2
gene id: 30608:BICD2
uniprot id: A0A8B7F4M3
uniprot id: A0A8B7XAL4
uniprot id: A0A8C5UYX2
uniprot id: A0A8C5VGF6
names: Similarity
messages: Belongs to the BicD family.

30608:KCNA3
gene id: 30608:KCNA3
uniprot id: A0A8B7FFN1
names: Subcellular Location Annotation
messages: Membrane

30608:KCNE1
gene id: 30608:KCNE1
uniprot id: A0A8B7F4D4
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the potassium channel KCNE family.
messages: Cell membrane
messages: Membrane

30608:ITGB2
gene id: 30608:ITGB2
uniprot id: A0A8B7HF09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft

30608:LOC109729817
gene id: 30608:LOC109729817
uniprot id: A0A8B7WT13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

30608:LOC105883353
gene id: 30608:LOC105883353
uniprot id: A0A8B7HUW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:FTH1
gene id: 30608:FTH1
uniprot id: A0A8B7HAH7
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

30608:PERP
gene id: 30608:PERP
uniprot id: A0A8C5YFE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

30608:CACNG6
gene id: 30608:CACNG6
uniprot id: A0A8B7GST3
uniprot id: A0A8B7GU90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit.

30608:LOC105881337
gene id: 30608:LOC105881337
uniprot id: A0A8B7HNZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

30608:RPS8
gene id: 30608:RPS8
uniprot id: A0A8B7H5T5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

30608:IK
gene id: 30608:IK
uniprot id: A0A8B7F8T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RED family.
messages: Nucleus

30608:LOC105864714
gene id: 30608:LOC105864714
uniprot id: A0A8B7FI27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MAN2A1
gene id: 30608:MAN2A1
uniprot id: A0A8C5VXE1
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

30608:ASB5
gene id: 30608:ASB5
uniprot id: A0A8B7GSI8
uniprot id: A0A8B7GTY9
uniprot id: A0A8C5XIW7
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

30608:CELF1
gene id: 30608:CELF1
uniprot id: A0A8B7I0Q3
uniprot id: A0A8B7I0R3
uniprot id: A0A8B7I0S3
uniprot id: A0A8B7I0U8
uniprot id: A0A8B7I307
uniprot id: A0A8B7I3R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

30608:LOC105881064
gene id: 30608:LOC105881064
uniprot id: A0A8B7WZP1
names: Subcellular Location Annotation
messages: Membrane

30608:AMHR2
gene id: 30608:AMHR2
uniprot id: A0A8B7GA19
uniprot id: A0A8B7GAH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane
messages: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.

30608:API5
gene id: 30608:API5
uniprot id: A0A8B7I5L1
uniprot id: A0A8B7I5M2
uniprot id: A0A8C5VWP2
names: Similarity
messages: Belongs to the API5 family.

30608:DUSP1
gene id: 30608:DUSP1
uniprot id: A0A8B7GEV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

30608:BAX
gene id: 30608:BAX
uniprot id: A0A8B7FM20
uniprot id: A0A8B7WV46
names: Similarity
messages: Belongs to the Bcl-2 family.

30608:ACTN1
gene id: 30608:ACTN1
uniprot id: A0A8B7HHA9
uniprot id: A0A8C5W0A5
uniprot id: A0A8C5WBD7
names: Similarity
messages: Belongs to the alpha-actinin family.

30608:TGM5
gene id: 30608:TGM5
uniprot id: A0A8C5VRF1
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

30608:CNNM2
gene id: 30608:CNNM2
uniprot id: A0A8B7GRG5
uniprot id: A0A8B7GRH6
uniprot id: A0A8C5V1W2
uniprot id: A0A8C5VBP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Cell membrane
messages: Membrane
messages: Metal transporter.

30608:MAP4K5
gene id: 30608:MAP4K5
uniprot id: A0A8B7FVK3
uniprot id: A0A8B7FWJ9
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

30608:LOC105855748
gene id: 30608:LOC105855748
uniprot id: A0A8B7EFR7
names: Caution
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:CTSZ
gene id: 30608:CTSZ
uniprot id: A0A8C5V2V2
names: Similarity
messages: Belongs to the peptidase C1 family.

30608:LOC105859568
gene id: 30608:LOC105859568
uniprot id: A0A8B7WPG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PPDPF
gene id: 30608:PPDPF
uniprot id: A0A8B7GXS2
names: Similarity
messages: Belongs to the PPDPF family.

30608:CDK6
gene id: 30608:CDK6
uniprot id: A0A8C5UQG5
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:LOC105885600
gene id: 30608:LOC105885600
uniprot id: A0A8B7I5F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CHD5
gene id: 30608:CHD5
uniprot id: A0A8B7I7M6
uniprot id: A0A8B7IAY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

30608:GBGT1
gene id: 30608:GBGT1
uniprot id: A0A8B7EW83
uniprot id: A0A8B7EY56
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Membrane

30608:TMEM136
gene id: 30608:TMEM136
uniprot id: A0A8B7GZ34
uniprot id: A0A8B7GZ46
uniprot id: A0A8B7GZ85
names: Subcellular Location Annotation
messages: Membrane

30608:SLC6A8
gene id: 30608:SLC6A8
uniprot id: A0A8B7FU12
uniprot id: A0A8B7FU13
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A8 subfamily.
messages: Cell membrane
messages: Membrane

30608:KIAA1429
gene id: 30608:KIAA1429
uniprot id: A0A8B7GXH2
uniprot id: A0A8B7X9S2
uniprot id: A0A8B7XBG2
names: Similarity
messages: Belongs to the vir family.

30608:CYFIP1
gene id: 30608:CYFIP1
uniprot id: A0A8B7XCH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYFIP family.
messages: synaptosome

30608:LOC105863676
gene id: 30608:LOC105863676
uniprot id: A0A8B7FE58
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Odorant receptor.

30608:ATP6AP1L
gene id: 30608:ATP6AP1L
uniprot id: A0A8B7HPU4
uniprot id: A0A8B7HRJ7
uniprot id: A0A8B7HS85
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

30608:EVL
gene id: 30608:EVL
uniprot id: A0A8B7F4E7
uniprot id: A0A8B7F4E8
uniprot id: A0A8B7F4E9
uniprot id: A0A8B7F4F0
uniprot id: A0A8B7F4F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration.
messages: cytoskeleton

30608:EBF4
gene id: 30608:EBF4
uniprot id: A0A8B7FP61
uniprot id: A0A8B7FPF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

30608:MASP2
gene id: 30608:MASP2
uniprot id: A0A8B7I780
uniprot id: A0A8B7I7D6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:PDE6D
gene id: 30608:PDE6D
uniprot id: A0A8B7EC81
uniprot id: A0A8C5VSU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PDE6D/unc-119 family.
messages: Cytoplasmic vesicle membrane
messages: Interacts with the prenylated catalytic subunits of PDE6, an oligomer composed of two catalytic chains and two inhibitory chains; has no effect on enzyme activity but promotes the release of the prenylated enzyme from cell membrane.
messages: Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.
messages: cilium basal body
messages: cytosol

30608:PBX4
gene id: 30608:PBX4
uniprot id: A0A8B7EPI2
uniprot id: A0A8B7EPM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

30608:NEU2
gene id: 30608:NEU2
uniprot id: A0A8C6EEI1
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

30608:LOC105884162
gene id: 30608:LOC105884162
uniprot id: A0A8B7HYL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MAP2K4
gene id: 30608:MAP2K4
uniprot id: A0A8B7H8M6
uniprot id: A0A8B7H8N5
uniprot id: A0A8C5VS12
uniprot id: A0A8C5W1W5
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:GRAMD1A
gene id: 30608:GRAMD1A
uniprot id: A0A8B7H2T1
uniprot id: A0A8B7H2T5
uniprot id: A0A8B7H4Z5
uniprot id: A0A8C5YGG5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:AP1B1
gene id: 30608:AP1B1
uniprot id: A0A8B7G9W1
uniprot id: A0A8B7GA71
uniprot id: A0A8B7GAH1
uniprot id: A0A8B7GAX8
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

30608:SEPT1
gene id: 30608:SEPT1
uniprot id: A0A8B7WPJ9
uniprot id: A0A8B7WQX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

30608:LOC105876723
gene id: 30608:LOC105876723
uniprot id: A0A8B7WSK7
names: Similarity
messages: Belongs to the serpin family.

30608:LOC105884167
gene id: 30608:LOC105884167
uniprot id: A0A8B7X407
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:RUNX1T1
gene id: 30608:RUNX1T1
uniprot id: A0A8B7FAE8
uniprot id: A0A8B7FAF1
uniprot id: A0A8B7FAK6
uniprot id: A0A8B7FB13
uniprot id: A0A8C5XJS4
names: Similarity
messages: Belongs to the CBFA2T family.

30608:KRT32
gene id: 30608:KRT32
uniprot id: A0A8B7GFQ2
names: Similarity
messages: Belongs to the intermediate filament family.

30608:PIK3CD
gene id: 30608:PIK3CD
uniprot id: A0A8B7I7C7
uniprot id: A0A8C5W077
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

30608:DDO
gene id: 30608:DDO
uniprot id: A0A8B7X6P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

30608:CRHR2
gene id: 30608:CRHR2
uniprot id: A0A8C5VX79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

30608:ARR3
gene id: 30608:ARR3
uniprot id: A0A8B7EBF8
names: Similarity
messages: Belongs to the arrestin family.

30608:PTRF
gene id: 30608:PTRF
uniprot id: A0A8C5VW25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

30608:SLC9A3
gene id: 30608:SLC9A3
uniprot id: A0A8C5V5H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Recycling endosome membrane

30608:LZIC
gene id: 30608:LZIC
uniprot id: A0A8C5Y0Y3
names: Similarity
messages: Belongs to the CTNNBIP1 family.

30608:ID1
gene id: 30608:ID1
uniprot id: A0A8C5W4V1
names: Subcellular Location Annotation
messages: Nucleus

30608:TTC4
gene id: 30608:TTC4
uniprot id: A0A8C5VE02
names: Similarity
messages: Belongs to the TTC4 family.

30608:CCNL2
gene id: 30608:CCNL2
uniprot id: A0A8B7H605
uniprot id: A0A8C5V2F3
uniprot id: A0A8C5VKN0
names: Similarity
messages: Belongs to the cyclin family.

30608:GLRB
gene id: 30608:GLRB
uniprot id: A0A8B7HQE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

30608:LOC105883399
gene id: 30608:LOC105883399
uniprot id: A0A8B7HX64
names: Subcellular Location Annotation
messages: Membrane

30608:LCNL1
gene id: 30608:LCNL1
uniprot id: A0A8B7HQ54
uniprot id: A0A8B7HQ66
uniprot id: A0A8B7HQ67
uniprot id: A0A8B7HRZ0
uniprot id: A0A8B7HSK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

30608:SMIM15
gene id: 30608:SMIM15
uniprot id: A0A8B7H6C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM15 family.
messages: Membrane

30608:LOC105877041
gene id: 30608:LOC105877041
uniprot id: A0A8B7H358
uniprot id: A0A8B7H362
uniprot id: A0A8B7H365
names: Similarity
messages: Belongs to the CD225/Dispanin family.

30608:LOC105879216
gene id: 30608:LOC105879216
uniprot id: A0A8B7HCY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MGMT
gene id: 30608:MGMT
uniprot id: A0A8B7HIU3
uniprot id: A0A8C5Y7J9
names: Function
names: Similarity
messages: Belongs to the MGMT family.
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

30608:HEPH
gene id: 30608:HEPH
uniprot id: A0A8B7EHZ2
uniprot id: A0A8B7EKD9
names: Similarity
messages: Belongs to the multicopper oxidase family.

30608:CLK1
gene id: 30608:CLK1
uniprot id: A0A8B7EJQ9
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:CDA
gene id: 30608:CDA
uniprot id: A0A8C5VXT6
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

30608:ABCG4
gene id: 30608:ABCG4
uniprot id: A0A8B7GZ62
uniprot id: A0A8B7GZ64
uniprot id: A0A8B7X3N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

30608:MOB1A
gene id: 30608:MOB1A
uniprot id: A0A8B7I0K0
uniprot id: A0A8B7I0K7
uniprot id: A0A8B7I2P3
uniprot id: A0A8B7X260
names: Similarity
messages: Belongs to the MOB1/phocein family.

30608:NANOS1
gene id: 30608:NANOS1
uniprot id: A0A8B7EIW8
names: Similarity
messages: Belongs to the nanos family.

30608:MAP3K11
gene id: 30608:MAP3K11
uniprot id: A0A8B7HA28
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

30608:TMEM175
gene id: 30608:TMEM175
uniprot id: A0A8B7HMJ1
uniprot id: A0A8B7HMJ5
uniprot id: A0A8B7HMJ8
uniprot id: A0A8B7HQ04
uniprot id: A0A8C5XMH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

30608:ACY1
gene id: 30608:ACY1
uniprot id: A0A8B7GVX3
uniprot id: A0A8C5XLZ9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cytoplasm

30608:NEDD4
gene id: 30608:NEDD4
uniprot id: A0A8B7HLR7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:FOXO1
gene id: 30608:FOXO1
uniprot id: A0A8B7FY36
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:SLC40A1
gene id: 30608:SLC40A1
uniprot id: A0A8B7H9I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
messages: Lateral cell membrane
messages: May be involved in iron transport and iron homeostasis.
messages: Membrane

30608:ASIC1
gene id: 30608:ASIC1
uniprot id: A0A8B7G596
uniprot id: A0A8B7G631
uniprot id: A0A8C5VAM6
names: Subcellular Location Annotation
messages: Membrane

30608:PTPRZ1
gene id: 30608:PTPRZ1
uniprot id: A0A8B7FUD5
uniprot id: A0A8B7XC08
uniprot id: A0A8B7XC09
uniprot id: A0A8B7XDQ9
uniprot id: A0A8B7XE93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
messages: Membrane

30608:ADGB
gene id: 30608:ADGB
uniprot id: A0A8B7FGR7
uniprot id: A0A8B7FGS9
uniprot id: A0A8B7FGU3
uniprot id: A0A8B7FGU8
uniprot id: A0A8B7FGZ1
uniprot id: A0A8B7FGZ8
uniprot id: A0A8B7FI11
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Belongs to the peptidase C2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:YPEL3
gene id: 30608:YPEL3
uniprot id: A0A8B7GBP3
uniprot id: A0A8C5XGX1
names: Similarity
messages: Belongs to the yippee family.

30608:PQLC3
gene id: 30608:PQLC3
uniprot id: A0A8B7X923
names: Subcellular Location Annotation
messages: Membrane

30608:DIO3
gene id: 30608:DIO3
uniprot id: A0A8B7F3Q7
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

30608:ZDHHC24
gene id: 30608:ZDHHC24
uniprot id: A0A8B7FVR6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

30608:LOC105885329
gene id: 30608:LOC105885329
uniprot id: A0A8B7I4C5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

30608:C4H2orf68
gene id: 30608:C4H2orf68
uniprot id: A0A8B7H149
names: Similarity
messages: Belongs to the UPF0561 family.

30608:LOC105863110
gene id: 30608:LOC105863110
uniprot id: A0A8B7FB05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105869212
gene id: 30608:LOC105869212
uniprot id: A0A8B7X6H2
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

30608:TMED1
gene id: 30608:TMED1
uniprot id: A0A8C5W5B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

30608:P2RX5
gene id: 30608:P2RX5
uniprot id: A0A8B7HCZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

30608:ADAMTS17
gene id: 30608:ADAMTS17
uniprot id: A0A8B7GBR7
uniprot id: A0A8B7GCR9
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:VPS37C
gene id: 30608:VPS37C
uniprot id: A0A8B7HAP1
uniprot id: A0A8B7HAP3
uniprot id: A0A8C5VS67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

30608:PTGR1
gene id: 30608:PTGR1
uniprot id: A0A8B7ED89
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer or homodimer.

30608:LOC105881601
gene id: 30608:LOC105881601
uniprot id: A0A8B7HM91
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105855661
gene id: 30608:LOC105855661
uniprot id: A0A8B7EDF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:EXOC6B
gene id: 30608:EXOC6B
uniprot id: A0A8B7FBI9
uniprot id: A0A8B7FBN0
uniprot id: A0A8C5V1Z6
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

30608:KIAA1191
gene id: 30608:KIAA1191
uniprot id: A0A8B7HI66
uniprot id: A0A8B7HJ48
uniprot id: A0A8B7WXL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P33MONOX family.
messages: Cytoplasm
messages: Interacts with NELFB, NOL12 and PRNP.
messages: Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth.

30608:ZNRF4
gene id: 30608:ZNRF4
uniprot id: A0A8B7G4V9
names: Subcellular Location Annotation
messages: Membrane

30608:KRT3
gene id: 30608:KRT3
uniprot id: A0A8B7G803
names: Similarity
messages: Belongs to the intermediate filament family.

30608:TPK1
gene id: 30608:TPK1
uniprot id: A0A8C5YAE6
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

30608:AQP10
gene id: 30608:AQP10
uniprot id: A0A8B7I6V9
uniprot id: A0A8B7WZU6
uniprot id: A0A8B7X1I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

30608:PI4KB
gene id: 30608:PI4KB
uniprot id: A0A8B7GJC8
uniprot id: A0A8B7GJD3
uniprot id: A0A8B7GJQ1
uniprot id: A0A8B7GK03
uniprot id: A0A8B7GKH7
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

30608:RASGRP2
gene id: 30608:RASGRP2
uniprot id: A0A8B7H9P6
uniprot id: A0A8B7H9Q2
uniprot id: A0A8B7H9R3
uniprot id: A0A8B7H9R7
uniprot id: A0A8B7X375
uniprot id: A0A8B7X430
names: Similarity
messages: Belongs to the RASGRP family.

30608:TAS2R10
gene id: 30608:TAS2R10
uniprot id: A0A8B7EPM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

30608:LOC105878856
gene id: 30608:LOC105878856
uniprot id: A0A8B7HBD8
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105883698
gene id: 30608:LOC105883698
uniprot id: A0A8B7HWM7
names: Similarity
messages: Belongs to the apolipoprotein L family.

30608:TCIRG1
gene id: 30608:TCIRG1
uniprot id: A0A8B7FUG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

30608:MCM7
gene id: 30608:MCM7
uniprot id: A0A8B7FZB2
uniprot id: A0A8C5VDZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

30608:MYH7B
gene id: 30608:MYH7B
uniprot id: A0A8B7FN83
uniprot id: A0A8B7FPC3
uniprot id: A0A8B7WQ57
uniprot id: A0A8B7WQ62
uniprot id: A0A8B7WQ63
uniprot id: A0A8B7WQ65
uniprot id: A0A8B7WQ68
uniprot id: A0A8B7WQ71
uniprot id: A0A8B7WQA4
uniprot id: A0A8B7WQB0
uniprot id: A0A8B7WRL9
uniprot id: A0A8B7WRM7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

30608:PROM1
gene id: 30608:PROM1
uniprot id: A0A8B7EES7
uniprot id: A0A8B7EET4
uniprot id: A0A8B7EFC9
uniprot id: A0A8B7EFD2
uniprot id: A0A8B7EFH9
uniprot id: A0A8B7EFI4
uniprot id: A0A8B7EHC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

30608:ADPRM
gene id: 30608:ADPRM
uniprot id: A0A8B7H8W1
uniprot id: A0A8B7H8X0
names: Similarity
names: Subunit
messages: Belongs to the ADPRibase-Mn family.
messages: Monomer.

30608:BUD23
gene id: 30608:BUD23
uniprot id: A0A8B7ERJ8
uniprot id: A0A8B7ETK7
uniprot id: A0A8C5V649
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

30608:SETD3
gene id: 30608:SETD3
uniprot id: A0A8C5W9T7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. SETD3 actin-histidine methyltransferase family.
messages: Cytoplasm
messages: Interacts with MYOD1.

30608:LOC105872191
gene id: 30608:LOC105872191
uniprot id: A0A8B7GGC2
names: Similarity
messages: Belongs to the intermediate filament family.

30608:LOC105876736
gene id: 30608:LOC105876736
uniprot id: A0A8B7H1E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF152 family.
messages: Lysosome membrane
messages: Membrane

30608:LOC105875574
gene id: 30608:LOC105875574
uniprot id: A0A8B7X6S4
uniprot id: A0A8B7X6T0
uniprot id: A0A8B7X8H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUSTOS family.
messages: Nucleus envelope

30608:NR4A1
gene id: 30608:NR4A1
uniprot id: A0A8B7G8T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR4 subfamily.
messages: In the cytosol, upon its detection of both bacterial lipopolysaccharide (LPS) and NBRE-containing mitochondrial DNA released by GSDMD pores during pyroptosis, it promotes non-canonical NLRP3 inflammasome activation by stimulating association of NLRP3 and NEK7.
messages: Nucleus
messages: cytosol

30608:ARID1A
gene id: 30608:ARID1A
uniprot id: A0A8B7FCW1
uniprot id: A0A8B7FCX2
uniprot id: A0A8B7FD31
uniprot id: A0A8C5W015
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105867461
gene id: 30608:LOC105867461
uniprot id: A0A8B7FUR9
uniprot id: A0A8B7FVL7
uniprot id: A0A8B7FVQ1
uniprot id: A0A8B7FVS0
uniprot id: A0A8B7FVT5
uniprot id: A0A8B7X7A0
uniprot id: A0A8C6EJB9
names: Similarity
messages: Belongs to the PROTOR family.

30608:LOC105856115
gene id: 30608:LOC105856115
uniprot id: A0A8B7EFP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF8 family.
messages: Nucleus

30608:LOC105859341
gene id: 30608:LOC105859341
uniprot id: A0A8B7EVL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:EGR3
gene id: 30608:EGR3
uniprot id: A0A8B7EJD0
uniprot id: A0A8B7EJE2
uniprot id: A0A8C5XU93
uniprot id: A0A8C5XVE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

30608:SSTR1
gene id: 30608:SSTR1
uniprot id: A0A8B7GIF6
uniprot id: A0A8B7GJ13
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:LOC105873394
gene id: 30608:LOC105873394
uniprot id: A0A8B7GLH8
uniprot id: A0A8B7GLI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

30608:SLC27A4
gene id: 30608:SLC27A4
uniprot id: A0A8C5VD75
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

30608:PADI1
gene id: 30608:PADI1
uniprot id: A0A8B7WP78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

30608:KDM4A
gene id: 30608:KDM4A
uniprot id: A0A8B7H6X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM3 histone demethylase family.
messages: Nucleus

30608:NCEH1
gene id: 30608:NCEH1
uniprot id: A0A8B7X2H3
uniprot id: A0A8C5YKW3
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

30608:AMELX
gene id: 30608:AMELX
uniprot id: A0A8B7HQZ3
names: Similarity
messages: Belongs to the amelogenin family.

30608:SCGB1A1
gene id: 30608:SCGB1A1
uniprot id: A0A8B7X3U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secretoglobin family.
messages: Secreted

30608:MSMP
gene id: 30608:MSMP
uniprot id: A0A8C5Y8W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

30608:RIMBP2
gene id: 30608:RIMBP2
uniprot id: A0A8B7WT15
uniprot id: A0A8B7WT20
uniprot id: A0A8B7WT25
uniprot id: A0A8B7WT29
uniprot id: A0A8B7WT67
uniprot id: A0A8B7WT72
uniprot id: A0A8B7WT75
uniprot id: A0A8B7WTC5
uniprot id: A0A8B7WUL1
uniprot id: A0A8B7WUM1
uniprot id: A0A8C5VH13
names: Similarity
messages: Belongs to the RIMBP family.

30608:TM9SF3
gene id: 30608:TM9SF3
uniprot id: A0A8B7GIQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

30608:IKBKAP
gene id: 30608:IKBKAP
uniprot id: A0A8B7ECY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP1/IKA1 family.
messages: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
messages: Cytoplasm
messages: Nucleus

30608:HMGA2
gene id: 30608:HMGA2
uniprot id: A0A8B7HK70
uniprot id: A0A8B7HK72
uniprot id: A0A8B7X5U8
uniprot id: A0A8C5Y9K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGA family.
messages: Nucleus

30608:CENPC
gene id: 30608:CENPC
uniprot id: A0A8B7G2Y1
uniprot id: A0A8C5XE88
names: Similarity
messages: Belongs to the CENP-C/MIF2 family.

30608:MYD88
gene id: 30608:MYD88
uniprot id: A0A8B7FS42
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
messages: Cytoplasm
messages: Homodimer. Also forms heterodimers with TIRAP. Binds to TLR2, TLR4, IRAK1, IRAK2 and IRAK4 via their respective TIR domains.

30608:RPL11
gene id: 30608:RPL11
uniprot id: A0A8B7FCQ6
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

30608:LOC105862112
gene id: 30608:LOC105862112
uniprot id: A0A8B7F700
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TAS2R4
gene id: 30608:TAS2R4
uniprot id: A0A8B7GL73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

30608:KIF22
gene id: 30608:KIF22
uniprot id: A0A8B7GBH8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:LOC105861278
gene id: 30608:LOC105861278
uniprot id: A0A8B7F2K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:RFC1
gene id: 30608:RFC1
uniprot id: A0A8B7FMD5
uniprot id: A0A8B7WSP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the activator 1 large subunit family.
messages: Nucleus

30608:CEMIP
gene id: 30608:CEMIP
uniprot id: A0A8B7FH38
names: Similarity
messages: Belongs to the CEMIP family.

30608:GPSM1
gene id: 30608:GPSM1
uniprot id: A0A8B7HJF4
uniprot id: A0A8C5XVW5
names: Similarity
messages: Belongs to the GPSM family.

30608:MOGAT2
gene id: 30608:MOGAT2
uniprot id: A0A8B7EYT7
uniprot id: A0A8C5XEI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane

30608:UNC13B
gene id: 30608:UNC13B
uniprot id: A0A8B7GQJ8
uniprot id: A0A8B7GQK2
uniprot id: A0A8B7GQK5
uniprot id: A0A8B7GQT8
uniprot id: A0A8B7GQU3
uniprot id: A0A8B7GQU8
uniprot id: A0A8B7GQY8
uniprot id: A0A8B7GQZ3
uniprot id: A0A8B7GS46
uniprot id: A0A8B7GS53
uniprot id: A0A8B7XB25
uniprot id: A0A8B7XB30
uniprot id: A0A8B7XBW3
uniprot id: A0A8B7XCR7
uniprot id: A0A8B7XD86
uniprot id: A0A8B7XD94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-13 family.
messages: Cytoplasm
messages: Membrane

30608:SMIM24
gene id: 30608:SMIM24
uniprot id: A0A8B7GNT2
names: Subcellular Location Annotation
messages: Membrane

30608:MAPK4
gene id: 30608:MAPK4
uniprot id: A0A8B7GQD4
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

30608:FAM212A
gene id: 30608:FAM212A
uniprot id: A0A8B7GTV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

30608:GMPPB
gene id: 30608:GMPPB
uniprot id: A0A8C5UZ59
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

30608:REM1
gene id: 30608:REM1
uniprot id: A0A8B7FPF3
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

30608:LOC105876721
gene id: 30608:LOC105876721
uniprot id: A0A8B7H1C2
names: Similarity
messages: Belongs to the serpin family.

30608:FMO3
gene id: 30608:FMO3
uniprot id: A0A8C5W282
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thrombus formation.
messages: Membrane
messages: Microsome membrane

30608:MRPS17
gene id: 30608:MRPS17
uniprot id: A0A8B7GBM4
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

30608:LOC105861301
gene id: 30608:LOC105861301
uniprot id: A0A8B7F2L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:FER1L6
gene id: 30608:FER1L6
uniprot id: A0A8C5XYW4
names: Similarity
messages: Belongs to the ferlin family.

30608:TIMM21
gene id: 30608:TIMM21
uniprot id: A0A8C5VJU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane
messages: Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes.

30608:MAPK8
gene id: 30608:MAPK8
uniprot id: A0A8B7EXB0
uniprot id: A0A8B7EXB5
uniprot id: A0A8B7EXC3
uniprot id: A0A8B7EXC4
uniprot id: A0A8B7EZD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

30608:BTD
gene id: 30608:BTD
uniprot id: A0A8B7GHU7
uniprot id: A0A8B7GHV1
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

30608:KCNJ13
gene id: 30608:KCNJ13
uniprot id: A0A8B7I7V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

30608:LOC105883365
gene id: 30608:LOC105883365
uniprot id: A0A8B7HUW3
names: Subcellular Location Annotation
messages: Membrane

30608:SLC6A15
gene id: 30608:SLC6A15
uniprot id: A0A8B7EN14
uniprot id: A0A8B7X7M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A15 subfamily.
messages: Membrane

30608:DACT1
gene id: 30608:DACT1
uniprot id: A0A8B7HSV8
uniprot id: A0A8B7HSW8
uniprot id: A0A8B7HSX0
uniprot id: A0A8B7HSX5
uniprot id: A0A8B7HSX9
uniprot id: A0A8B7HSY5
uniprot id: A0A8B7HSZ0
uniprot id: A0A8B7HSZ5
uniprot id: A0A8B7HUY5
uniprot id: A0A8B7HUZ5
uniprot id: A0A8B7HV62
uniprot id: A0A8B7HV65
uniprot id: A0A8B7HV69
names: Similarity
messages: Belongs to the dapper family.

30608:PYY
gene id: 30608:PYY
uniprot id: A0A8B7HVL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

30608:JUNB
gene id: 30608:JUNB
uniprot id: A0A8B7I4Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

30608:LOC105862782
gene id: 30608:LOC105862782
uniprot id: A0A8B7FA71
names: Similarity
names: Subunit
messages: Belongs to the GST superfamily. Theta family.
messages: Homodimer.

30608:LOC105884095
gene id: 30608:LOC105884095
uniprot id: A0A8B7HYE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NMS
gene id: 30608:NMS
uniprot id: A0A8B7X3R2
uniprot id: A0A8B7X449
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NmU family.
messages: Secreted

30608:SPESP1
gene id: 30608:SPESP1
uniprot id: A0A8B7GLC1
uniprot id: A0A8B7X1T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPESP1 family.
messages: Involved in fertilization ability of sperm.
messages: acrosome

30608:TMEM255B
gene id: 30608:TMEM255B
uniprot id: A0A8B7XDG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

30608:LOC105865940
gene id: 30608:LOC105865940
uniprot id: A0A8B7FNV1
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

30608:GNG2
gene id: 30608:GNG2
uniprot id: A0A8B7X2U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

30608:ELP6
gene id: 30608:ELP6
uniprot id: A0A8C5V855
names: Similarity
messages: Belongs to the ELP6 family.

30608:GADD45B
gene id: 30608:GADD45B
uniprot id: A0A8B7GPG8
names: Similarity
messages: Belongs to the GADD45 family.

30608:APLP1
gene id: 30608:APLP1
uniprot id: A0A8C5W542
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:CHMP2B
gene id: 30608:CHMP2B
uniprot id: A0A8B7EVI1
names: Similarity
messages: Belongs to the SNF7 family.

30608:ST6GALNAC1
gene id: 30608:ST6GALNAC1
uniprot id: A0A8B7HC04
uniprot id: A0A8B7HC10
uniprot id: A0A8B7HC11
uniprot id: A0A8B7HC12
uniprot id: A0A8B7HEP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

30608:CDPF1
gene id: 30608:CDPF1
uniprot id: A0A8B7FTP1
uniprot id: A0A8B7FTS8
names: Similarity
messages: Belongs to the CDPF1 family.

30608:C3
gene id: 30608:C3
uniprot id: A0A8B7WVJ2
uniprot id: A0A8B7WVU7
uniprot id: A0A8B7WW58
names: Function
names: Subcellular Location Annotation
messages: Acts as a chemoattractant for neutrophils in chronic inflammation.
messages: C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.
messages: Secreted

30608:SCN10A
gene id: 30608:SCN10A
uniprot id: A0A8B7ER88
uniprot id: A0A8B7ERA5
uniprot id: A0A8B7ET02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

30608:ST7
gene id: 30608:ST7
uniprot id: A0A8B7G346
uniprot id: A0A8B7G347
uniprot id: A0A8B7G351
uniprot id: A0A8B7G352
uniprot id: A0A8B7G353
uniprot id: A0A8B7G356
uniprot id: A0A8B7G359
uniprot id: A0A8B7G360
uniprot id: A0A8B7G363
uniprot id: A0A8B7G364
uniprot id: A0A8B7G3Z8
uniprot id: A0A8B7G403
uniprot id: Q2QL86
uniprot id: Q2QL87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

30608:HSDL1
gene id: 30608:HSDL1
uniprot id: A0A8C5XX06
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:GNAL
gene id: 30608:GNAL
uniprot id: A0A8B7WRG5
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

30608:SNX20
gene id: 30608:SNX20
uniprot id: A0A8B7GBC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Membrane

30608:NCOA3
gene id: 30608:NCOA3
uniprot id: A0A8B7ETC1
uniprot id: A0A8B7ETC5
uniprot id: A0A8B7EV75
uniprot id: A0A8B7EVC7
uniprot id: A0A8B7WQH4
uniprot id: A0A8B7WQH6
uniprot id: A0A8B7WQL8
uniprot id: A0A8B7WRZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

30608:GOLGA5
gene id: 30608:GOLGA5
uniprot id: A0A8B7EIF2
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.

30608:PSAT1
gene id: 30608:PSAT1
uniprot id: A0A8B7G059
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.

30608:LOC105883741
gene id: 30608:LOC105883741
uniprot id: A0A8B7WRS2
names: Similarity
messages: Belongs to the serpin family.

30608:BCAT1
gene id: 30608:BCAT1
uniprot id: A0A8B7EK11
uniprot id: A0A8B7EL94
uniprot id: A0A8B7EMD6
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

30608:FAM69C
gene id: 30608:FAM69C
uniprot id: A0A8B7WSJ8
names: Similarity
messages: Belongs to the DIPK family.

30608:LOC105885422
gene id: 30608:LOC105885422
uniprot id: A0A8B7I4M5
uniprot id: A0A8B7I6N0
uniprot id: A0A8B7I7R6
names: Similarity
messages: Belongs to the SH3BGR family.

30608:HOXA9
gene id: 30608:HOXA9
uniprot id: A0A8B7GYU5
uniprot id: A0A8C5Y2P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

30608:KCNA2
gene id: 30608:KCNA2
uniprot id: A0A8B7FFL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.2/KCNA2 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Presynaptic cell membrane
messages: Synaptic cell membrane
messages: lamellipodium membrane
messages: paranodal septate junction
messages: synaptosome

30608:OPRD1
gene id: 30608:OPRD1
uniprot id: A0A8B7FDG8
uniprot id: A0A8B7FDH4
uniprot id: A0A8B7FEC4
uniprot id: A0A8C5Y7Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SFXN2
gene id: 30608:SFXN2
uniprot id: A0A8B7GR03
uniprot id: A0A8B7GR44
uniprot id: A0A8B7GSH3
uniprot id: A0A8C5UZH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane
messages: Mitochondrion membrane

30608:PNLDC1
gene id: 30608:PNLDC1
uniprot id: A0A8B7FZS4
uniprot id: A0A8B7FZT6
uniprot id: A0A8B7FZW1
names: Similarity
messages: Belongs to the CAF1 family.

30608:BCR
gene id: 30608:BCR
uniprot id: A0A8B7F9N6
uniprot id: A0A8B7WSZ1
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

30608:PPIP5K1
gene id: 30608:PPIP5K1
uniprot id: A0A8B7GH08
uniprot id: A0A8B7GH14
uniprot id: A0A8B7GH19
uniprot id: A0A8B7GH26
uniprot id: A0A8B7GH29
uniprot id: A0A8B7GH35
uniprot id: A0A8B7GHG3
uniprot id: A0A8B7GHG8
uniprot id: A0A8B7GHQ9
uniprot id: A0A8B7GHR4
uniprot id: A0A8B7GHS0
uniprot id: A0A8B7GHS5
uniprot id: A0A8B7GHW8
uniprot id: A0A8B7GHX9
uniprot id: A0A8C5VW69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

30608:ALOXE3
gene id: 30608:ALOXE3
uniprot id: A0A8B7H6H0
uniprot id: A0A8B7H6I0
uniprot id: A0A8C5W5M1
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:AP3B1
gene id: 30608:AP3B1
uniprot id: A0A8B7GHC5
uniprot id: A0A8B7GHR6
uniprot id: A0A8C5XNN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

30608:MUT
gene id: 30608:MUT
uniprot id: A0A8B7G413
uniprot id: A0A8C5V150
names: Function
names: Similarity
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle.

30608:ESCO2
gene id: 30608:ESCO2
uniprot id: A0A8C5XFC6
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105878814
gene id: 30608:LOC105878814
uniprot id: A0A8B7HB71
uniprot id: A0A8B7HB72
uniprot id: A0A8B7HDW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

30608:C8H2orf76
gene id: 30608:C8H2orf76
uniprot id: A0A8B7F9G5
uniprot id: A0A8B7X8N9
names: Similarity
messages: Belongs to the UPF0538 family.

30608:GJB4
gene id: 30608:GJB4
uniprot id: A0A8B7GDM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

30608:DDR1
gene id: 30608:DDR1
uniprot id: A0A8B7EBU5
uniprot id: A0A8B7ECG8
uniprot id: A0A8B7ECH4
uniprot id: A0A8B7EEH7
uniprot id: A0A8C5YAH8
names: Subcellular Location Annotation
messages: Membrane

30608:MAPK8IP3
gene id: 30608:MAPK8IP3
uniprot id: A0A8B7EUK1
uniprot id: A0A8B7EUK3
uniprot id: A0A8B7EUK6
uniprot id: A0A8B7EUK9
uniprot id: A0A8B7EUL0
uniprot id: A0A8B7EUL1
uniprot id: A0A8B7EUL4
uniprot id: A0A8B7EUL5
uniprot id: A0A8B7EUL9
uniprot id: A0A8B7EWJ5
uniprot id: A0A8B7EWJ8
uniprot id: A0A8B7EWK0
uniprot id: A0A8B7EWK6
uniprot id: A0A8B7EWK9
names: Similarity
messages: Belongs to the JIP scaffold family.

30608:PROC
gene id: 30608:PROC
uniprot id: A0A8B7X9F7
uniprot id: A0A8B7XAD7
uniprot id: A0A8B7XAR7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:DVL2
gene id: 30608:DVL2
uniprot id: A0A8B7H7I0
uniprot id: A0A8B7H7J5
names: Similarity
messages: Belongs to the DSH family.

30608:GNB1
gene id: 30608:GNB1
uniprot id: A0A8B7WNM6
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

30608:SORCS1
gene id: 30608:SORCS1
uniprot id: A0A8B7GSG3
uniprot id: A0A8B7GSI7
uniprot id: A0A8B7GSR4
uniprot id: A0A8B7GU76
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

30608:HPS5
gene id: 30608:HPS5
uniprot id: A0A8B7X356
names: Similarity
messages: Belongs to the HPS5 family.

30608:LOC105864669
gene id: 30608:LOC105864669
uniprot id: A0A8B7FHX4
names: Subcellular Location Annotation
messages: Membrane

30608:ABCC6
gene id: 30608:ABCC6
uniprot id: A0A8B7WPN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

30608:SRM
gene id: 30608:SRM
uniprot id: A0A8B7I799
uniprot id: A0A8B7IAK4
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

30608:GOT1L1
gene id: 30608:GOT1L1
uniprot id: A0A8B7G7U2
uniprot id: A0A8B7G806
uniprot id: A0A8B7G8I0
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

30608:LOC105858942
gene id: 30608:LOC105858942
uniprot id: A0A8B7ERT3
uniprot id: A0A8B7ETK1
uniprot id: A0A8C5XGL7
names: Similarity
messages: Belongs to the cytochrome b5 family.

30608:FOXN2
gene id: 30608:FOXN2
uniprot id: A0A8B7FR43
names: Subcellular Location Annotation
messages: Nucleus

30608:PLPPR5
gene id: 30608:PLPPR5
uniprot id: A0A8B7GQB2
uniprot id: A0A8B7GQB4
uniprot id: A0A8B7GQQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

30608:MYO3B
gene id: 30608:MYO3B
uniprot id: A0A8B7HJ30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: In the C-terminal section; belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: cytoskeleton

30608:RAD54L2
gene id: 30608:RAD54L2
uniprot id: A0A8B7GU00
uniprot id: A0A8B7GU51
uniprot id: A0A8B7GU56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

30608:LOC105880279
gene id: 30608:LOC105880279
uniprot id: A0A8B7HHF0
uniprot id: A0A8B7HK15
uniprot id: A0A8B7HK20
uniprot id: A0A8C5VWF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Membrane
messages: Mitochondrion inner membrane

30608:CDX1
gene id: 30608:CDX1
uniprot id: A0A8B7EQ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

30608:LOC105862655
gene id: 30608:LOC105862655
uniprot id: A0A8B7F968
names: Similarity
messages: Belongs to the PRR23 family.

30608:LOC105860454
gene id: 30608:LOC105860454
uniprot id: A0A8B7EZ11
uniprot id: A0A8C5UYF5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:KCNMB4
gene id: 30608:KCNMB4
uniprot id: A0A8B7I2Y2
uniprot id: A0A8B7I3M9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KCNMB (TC 8.A.14.1) family.
messages: Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB per KCNMA1 tetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-glycosylated.
messages: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

30608:METAP2
gene id: 30608:METAP2
uniprot id: A0A8B7H3I7
uniprot id: A0A8B7X6V0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Binds EIF2S1 at low magnesium concentrations. Interacts strongly with the eIF-2 gamma-subunit EIF2S3.
messages: Contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. O-glycosylation is required for EIF2S1 binding.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm
messages: Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.

30608:LOC105866577
gene id: 30608:LOC105866577
uniprot id: A0A8B7FR49
names: Similarity
messages: Belongs to the SPATA31 family.

30608:IFI6
gene id: 30608:IFI6
uniprot id: A0A8B7FEF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane

30608:FOXE3
gene id: 30608:FOXE3
uniprot id: A0A8B7H5U2
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105867578
gene id: 30608:LOC105867578
uniprot id: A0A8B7FWB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative pheromone receptor.

30608:ATP6V1D
gene id: 30608:ATP6V1D
uniprot id: A0A8B7X1D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase D subunit family.
messages: cilium
messages: clathrin-coated vesicle membrane

30608:LOC105881192
gene id: 30608:LOC105881192
uniprot id: A0A8B7X1Z3
uniprot id: A0A8B7X3P7
names: Subcellular Location Annotation
messages: Chromosome

30608:TYSND1
gene id: 30608:TYSND1
uniprot id: A0A8B7G6Z5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1B family.
messages: Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.
messages: Peroxisome
messages: The full-lengh TYSND1 is the active the proteolytic processing of PTS1- and PTS2-proteins and in self-cleavage, and intermolecular self-cleavage of TYSND1 down-regulates its protease activity.

30608:LOC105881899
gene id: 30608:LOC105881899
uniprot id: A0A8B7WPL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

30608:LOC105877012
gene id: 30608:LOC105877012
uniprot id: A0A8C5XMJ1
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

30608:FGF13
gene id: 30608:FGF13
uniprot id: A0A8B7HMY3
uniprot id: A0A8C5XF91
uniprot id: A0A8C6EI31
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

30608:HMOX1
gene id: 30608:HMOX1
uniprot id: A0A8B7HZ44
names: Similarity
messages: Belongs to the heme oxygenase family.

30608:LNPEP
gene id: 30608:LNPEP
uniprot id: A0A8B7GZN6
uniprot id: A0A8C5Y2F2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

30608:LOC105863118
gene id: 30608:LOC105863118
uniprot id: A0A8B7FB27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CBLB
gene id: 30608:CBLB
uniprot id: A0A8B7H7V4
uniprot id: A0A8B7H7X1
uniprot id: A0A8B7H7X6
uniprot id: A0A8B7X828
names: Domain
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

30608:NOC3L
gene id: 30608:NOC3L
uniprot id: A0A8B7GH02
uniprot id: A0A8B7GH43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: nucleolus

30608:MRPL30
gene id: 30608:MRPL30
uniprot id: A0A8B7HWG3
uniprot id: A0A8B7HWG4
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

30608:TBC1D31
gene id: 30608:TBC1D31
uniprot id: A0A8B7EU71
uniprot id: A0A8B7EU77
uniprot id: A0A8B7EW61
names: Function
names: Subcellular Location Annotation
messages: Molecular adapter which is involved in cilium biogenesis. Part of a functional complex including OFD1 a centriolar protein involved in cilium assembly. Could regulate the cAMP-dependent phosphorylation of OFD1, and its subsequent ubiquitination by PJA2 which ultimately leads to its proteasomal degradation.
messages: centriolar satellite
messages: cilium basal body

30608:MTTP
gene id: 30608:MTTP
uniprot id: A0A8B7EHH5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105868198
gene id: 30608:LOC105868198
uniprot id: A0A8B7FXP8
uniprot id: A0A8B7FXR5
uniprot id: A0A8B7FXW7
uniprot id: A0A8B7FYP9
uniprot id: A0A8B7FYU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm
messages: nucleoplasm

30608:KIF20B
gene id: 30608:KIF20B
uniprot id: A0A8B7GE96
uniprot id: A0A8B7GED0
uniprot id: A0A8B7GEH8
uniprot id: A0A8B7GEI9
uniprot id: A0A8B7GEJ9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:EIF2B5
gene id: 30608:EIF2B5
uniprot id: A0A8C5YK80
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

30608:KIF17
gene id: 30608:KIF17
uniprot id: A0A8B7HY12
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:ASXL2
gene id: 30608:ASXL2
uniprot id: A0A8B7HZA1
uniprot id: A0A8B7I1C3
uniprot id: A0A8B7I1Z6
uniprot id: A0A8C5Y6C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asx family.
messages: Nucleus

30608:IRAK2
gene id: 30608:IRAK2
uniprot id: A0A8B7G205
uniprot id: A0A8B7G208
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
messages: Interacts with MYD88. IL-1 stimulation leads to the formation of a signaling complex which dissociates from the IL-1 receptor following the binding of PELI1.

30608:NELFE
gene id: 30608:NELFE
uniprot id: A0A8B7ENR8
uniprot id: A0A8C5W6J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NELF-E family.
messages: Chromosome
messages: Nucleus

30608:CLSTN2
gene id: 30608:CLSTN2
uniprot id: A0A8B7G657
uniprot id: A0A8B7G659
uniprot id: A0A8B7G7D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsyntenin family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Postsynaptic cell membrane

30608:PABPC4
gene id: 30608:PABPC4
uniprot id: A0A8B7XAE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

30608:CEP63
gene id: 30608:CEP63
uniprot id: A0A8B7HYC6
uniprot id: A0A8B7HYD2
uniprot id: A0A8B7HYD3
uniprot id: A0A8B7I0F3
uniprot id: A0A8B7I126
uniprot id: A0A8C5YH32
names: Similarity
messages: Belongs to the CEP63 family.

30608:LOC105865503
gene id: 30608:LOC105865503
uniprot id: A0A8B7FLQ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:DLK1
gene id: 30608:DLK1
uniprot id: A0A8B7F3N6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:WNT7A
gene id: 30608:WNT7A
uniprot id: A0A8B7FHF2
uniprot id: A0A8B7FIQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

30608:TFF2
gene id: 30608:TFF2
uniprot id: A0A8B7HCC7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:PTPRS
gene id: 30608:PTPRS
uniprot id: A0A8B7WVT9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

30608:SERPINB6
gene id: 30608:SERPINB6
uniprot id: A0A8B7GLW2
uniprot id: A0A8B7GMV0
uniprot id: A0A8C5VGQ2
names: Similarity
messages: Belongs to the serpin family.

30608:AES
gene id: 30608:AES
uniprot id: A0A8B7GNW1
uniprot id: A0A8B7GPD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

30608:LOC105858292
gene id: 30608:LOC105858292
uniprot id: A0A8B7ERC9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:B4GALNT3
gene id: 30608:B4GALNT3
uniprot id: A0A8B7F7B4
uniprot id: A0A8B7F7I7
uniprot id: A0A8B7X8S1
uniprot id: A0A8C5UTZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

30608:MALL
gene id: 30608:MALL
uniprot id: A0A8B7ET05
names: Subcellular Location Annotation
messages: Membrane

30608:IGF2
gene id: 30608:IGF2
uniprot id: A0A8B7EVX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
messages: Secreted

30608:LOC105863530
gene id: 30608:LOC105863530
uniprot id: A0A8B7FE39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RSRP family.
messages: Nucleus
messages: Probably acts as a spliceosomal factor that contributes to spliceosome assembly and regulates the isoform switching of proteins such as PARP6.

30608:LOC105882248
gene id: 30608:LOC105882248
uniprot id: A0A8B7HQ10
uniprot id: A0A8B7HQ16
uniprot id: A0A8B7HQ21
uniprot id: A0A8B7HRU0
uniprot id: A0A8B7HRU5
uniprot id: A0A8B7HSG1
uniprot id: A0A8B7HSG3
uniprot id: A0A8C5XC71
names: Similarity
messages: Belongs to the cullin family.

30608:SPECC1
gene id: 30608:SPECC1
uniprot id: A0A8B7EFQ2
uniprot id: A0A8B7EFQ5
uniprot id: A0A8B7EFQ7
uniprot id: A0A8B7EG88
uniprot id: A0A8B7EGK3
uniprot id: A0A8B7EI86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

30608:SOX11
gene id: 30608:SOX11
uniprot id: A0A8B7I910
names: Subcellular Location Annotation
messages: Nucleus

30608:MGAT2
gene id: 30608:MGAT2
uniprot id: A0A8B7FWL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 16 (GT16) protein family.
messages: Golgi apparatus membrane
messages: Membrane

30608:GNRH1
gene id: 30608:GNRH1
uniprot id: A0A8B7HKR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GnRH family.
messages: Secreted
messages: Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.

30608:POLR2L
gene id: 30608:POLR2L
uniprot id: A0A8B7X478
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

30608:RRH
gene id: 30608:RRH
uniprot id: A0A8B7GGD5
uniprot id: A0A8C5VZD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

30608:SMOC1
gene id: 30608:SMOC1
uniprot id: A0A8B7HHD5
uniprot id: A0A8B7HHG5
uniprot id: A0A8B7HI73
uniprot id: A0A8B7HK06
uniprot id: A0A8C6EH37
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105880087
gene id: 30608:LOC105880087
uniprot id: A0A8B7HGP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

30608:KCNH6
gene id: 30608:KCNH6
uniprot id: A0A8B7F4T7
uniprot id: A0A8B7F4V2
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105870538
gene id: 30608:LOC105870538
uniprot id: A0A8B7G8I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105864412
gene id: 30608:LOC105864412
uniprot id: A0A8B7FH01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LIM2
gene id: 30608:LIM2
uniprot id: A0A8B7HSL1
uniprot id: A0A8B7HUM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis.

30608:MAN1B1
gene id: 30608:MAN1B1
uniprot id: A0A8B7XDR7
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

30608:CPXM1
gene id: 30608:CPXM1
uniprot id: A0A8B7FPL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

30608:ERLIN1
gene id: 30608:ERLIN1
uniprot id: A0A8B7GLG6
uniprot id: A0A8B7GLH5
uniprot id: A0A8B7GLI5
uniprot id: A0A8B7GM14
uniprot id: A0A8B7GMS2
uniprot id: A0A8B7WMQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the band 7/mec-2 family.
messages: Endoplasmic reticulum membrane
messages: Mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway.
messages: Membrane

30608:CLCC1
gene id: 30608:CLCC1
uniprot id: A0A8B7FGL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel MCLC family.
messages: Membrane

30608:ELSPBP1
gene id: 30608:ELSPBP1
uniprot id: A0A8B7G4H1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105884087
gene id: 30608:LOC105884087
uniprot id: A0A8B7X3W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MRPS24
gene id: 30608:MRPS24
uniprot id: A0A8B7EPT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Mitochondrion

30608:LOC105879965
gene id: 30608:LOC105879965
uniprot id: A0A8B7HGV5
names: Function
names: Similarity
messages: Belongs to the SAA family.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.

30608:ATP13A2
gene id: 30608:ATP13A2
uniprot id: A0A8B7WPC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

30608:SND1
gene id: 30608:SND1
uniprot id: A0A8B7I1Q7
uniprot id: A0A8C5UKL8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs.

30608:TMEM50A
gene id: 30608:TMEM50A
uniprot id: A0A8C5YEE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

30608:HAL
gene id: 30608:HAL
uniprot id: A0A8B7H3E2
names: Similarity
messages: Belongs to the PAL/histidase family.

30608:CD320
gene id: 30608:CD320
uniprot id: A0A8C5YFL9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:SERPINB10
gene id: 30608:SERPINB10
uniprot id: A0A8B7H1C4
names: Similarity
messages: Belongs to the serpin family.

30608:CRBN
gene id: 30608:CRBN
uniprot id: A0A8B7WX43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRBN family.
messages: Nucleus

30608:UNC5CL
gene id: 30608:UNC5CL
uniprot id: A0A8B7G2H3
uniprot id: A0A8B7G2I0
names: Similarity
messages: Belongs to the unc-5 family.

30608:PSME4
gene id: 30608:PSME4
uniprot id: A0A8B7H992
uniprot id: A0A8B7H9A1
uniprot id: A0A8C5XMM3
names: Similarity
messages: Belongs to the BLM10 family.

30608:ELL2
gene id: 30608:ELL2
uniprot id: A0A8C5UXJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

30608:NEFL
gene id: 30608:NEFL
uniprot id: A0A8C5VXU9
names: Similarity
messages: Belongs to the intermediate filament family.

30608:CERS5
gene id: 30608:CERS5
uniprot id: A0A8B7G5P0
uniprot id: A0A8B7G6W0
uniprot id: A0A8C5XEN9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

30608:MFSD1
gene id: 30608:MFSD1
uniprot id: A0A8B7EKG3
uniprot id: A0A8B7EKT0
names: Subcellular Location Annotation
messages: Membrane

30608:BAZ2B
gene id: 30608:BAZ2B
uniprot id: A0A8B7EYZ4
uniprot id: A0A8B7EYZ7
uniprot id: A0A8B7EYZ8
uniprot id: A0A8B7EYZ9
uniprot id: A0A8B7EZ04
uniprot id: A0A8B7EZ05
uniprot id: A0A8B7F0R1
uniprot id: A0A8B7F0R8
uniprot id: A0A8B7F0S4
uniprot id: A0A8B7F151
uniprot id: A0A8B7F156
uniprot id: A0A8B7F165
uniprot id: A0A8B7X8I6
uniprot id: A0A8B7X8I7
uniprot id: A0A8B7XAJ5
names: Similarity
messages: Belongs to the WAL family.

30608:STIM1
gene id: 30608:STIM1
uniprot id: A0A8B7EY67
uniprot id: A0A8B7EY69
uniprot id: A0A8B7EY70
uniprot id: A0A8B7F011
uniprot id: A0A8C5VIK8
uniprot id: A0A8C5XPT6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:BARX2
gene id: 30608:BARX2
uniprot id: A0A8B7FF78
uniprot id: A0A8B7FFF1
names: Subcellular Location Annotation
messages: Nucleus

30608:CXCL13
gene id: 30608:CXCL13
uniprot id: A0A8B7F1A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

30608:DNAH8
gene id: 30608:DNAH8
uniprot id: A0A8B7F341
names: Similarity
messages: Belongs to the dynein heavy chain family.

30608:SEMA6A
gene id: 30608:SEMA6A
uniprot id: A0A8C5Y683
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:SFRP4
gene id: 30608:SFRP4
uniprot id: A0A8B7H8S2
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:CNR2
gene id: 30608:CNR2
uniprot id: A0A8B7FCX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PHKA2
gene id: 30608:PHKA2
uniprot id: A0A8B7HQJ3
uniprot id: A0A8B7HQJ5
uniprot id: A0A8B7HQJ9
uniprot id: A0A8C5UTJ2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

30608:B3GALT1
gene id: 30608:B3GALT1
uniprot id: A0A8B7XAB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:AKAP3
gene id: 30608:AKAP3
uniprot id: A0A8B7HLV6
uniprot id: A0A8B7HLV8
uniprot id: A0A8B7HN93
names: Similarity
messages: Belongs to the AKAP110 family.

30608:ENTPD1
gene id: 30608:ENTPD1
uniprot id: A0A8B7GHY1
uniprot id: A0A8B7GI18
uniprot id: A0A8B7GIA6
uniprot id: A0A8B7GIL5
uniprot id: A0A8B7GIX2
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

30608:CDC5L
gene id: 30608:CDC5L
uniprot id: A0A8C5UU58
names: Similarity
messages: Belongs to the CEF1 family.

30608:TSPAN14
gene id: 30608:TSPAN14
uniprot id: A0A8B7GCM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

30608:TUBB4A
gene id: 30608:TUBB4A
uniprot id: A0A8B7G4P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

30608:TNFRSF11B
gene id: 30608:TNFRSF11B
uniprot id: A0A8C5V3I3
names: Caution
names: Function
names: Subunit
messages: Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:ENTPD6
gene id: 30608:ENTPD6
uniprot id: A0A8B7F218
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

30608:NEURL2
gene id: 30608:NEURL2
uniprot id: A0A8B7ET65
names: Subcellular Location Annotation
messages: Cytoplasm

30608:LOC105885321
gene id: 30608:LOC105885321
uniprot id: A0A8B7I4D2
names: Similarity
messages: Belongs to the NPIP family.

30608:LOC105874730
gene id: 30608:LOC105874730
uniprot id: A0A8B7GUA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

30608:ITGB8
gene id: 30608:ITGB8
uniprot id: A0A8B7HH42
uniprot id: A0A8B7XE24
uniprot id: A0A8C5XVZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

30608:NEK6
gene id: 30608:NEK6
uniprot id: A0A8C6EE99
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:SCNN1A
gene id: 30608:SCNN1A
uniprot id: A0A8B7G3G1
uniprot id: A0A8B7X6W4
uniprot id: A0A8B7X880
names: Subcellular Location Annotation
messages: Membrane

30608:PSME2
gene id: 30608:PSME2
uniprot id: A0A8B7FRM1
names: Similarity
messages: Belongs to the PA28 family.

30608:MERTK
gene id: 30608:MERTK
uniprot id: A0A8C5UUI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

30608:LOC105864410
gene id: 30608:LOC105864410
uniprot id: A0A8B7FIA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SH3BGRL3
gene id: 30608:SH3BGRL3
uniprot id: A0A8B7FCT3
names: Similarity
messages: Belongs to the SH3BGR family.

30608:RHBDL2
gene id: 30608:RHBDL2
uniprot id: A0A8B7HEE0
names: Subcellular Location Annotation
messages: Membrane

30608:SERINC3
gene id: 30608:SERINC3
uniprot id: A0A8B7HGM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

30608:ELK1
gene id: 30608:ELK1
uniprot id: A0A8B7F7D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

30608:PATJ
gene id: 30608:PATJ
uniprot id: A0A8B7GI43
names: Subcellular Location Annotation
messages: tight junction

30608:ABAT
gene id: 30608:ABAT
uniprot id: A0A8B7HU33
names: Similarity
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer; disulfide-linked.

30608:NKAPL
gene id: 30608:NKAPL
uniprot id: A0A8B7ESV6
names: Similarity
messages: Belongs to the NKAP family.

30608:KIF13A
gene id: 30608:KIF13A
uniprot id: A0A8B7WKC3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:NLGN2
gene id: 30608:NLGN2
uniprot id: A0A8B7H664
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

30608:DCP1A
gene id: 30608:DCP1A
uniprot id: A0A8B7WL13
uniprot id: A0A8B7WL42
names: Similarity
messages: Belongs to the DCP1 family.

30608:C19H5orf24
gene id: 30608:C19H5orf24
uniprot id: A0A8B7G5X9
uniprot id: A0A8B7G607
names: Similarity
messages: Belongs to the UPF0461 family.

30608:FAM110A
gene id: 30608:FAM110A
uniprot id: A0A8B7FPB9
names: Similarity
messages: Belongs to the FAM110 family.

30608:DNASE1L1
gene id: 30608:DNASE1L1
uniprot id: A0A8C5VBD8
names: Similarity
messages: Belongs to the DNase I family.

30608:TBX10
gene id: 30608:TBX10
uniprot id: A0A8B7FUF6
uniprot id: A0A8B7FUF9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

30608:LOC105882596
gene id: 30608:LOC105882596
uniprot id: A0A8B7HU29
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:RTCA
gene id: 30608:RTCA
uniprot id: A0A8B7F843
uniprot id: A0A8C5UWE5
names: Function
names: Similarity
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.

30608:SLC25A27
gene id: 30608:SLC25A27
uniprot id: A0A8B7X4N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:LOC105880094
gene id: 30608:LOC105880094
uniprot id: A0A8B7HGP6
names: Function
names: Subunit
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

30608:LOC105874211
gene id: 30608:LOC105874211
uniprot id: A0A8B7XAH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

30608:ABCA13
gene id: 30608:ABCA13
uniprot id: A0A8B7XCI3
names: Subcellular Location Annotation
messages: Membrane

30608:ELF1
gene id: 30608:ELF1
uniprot id: A0A8B7GDC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

30608:TENM1
gene id: 30608:TENM1
uniprot id: A0A8B7FZK7
uniprot id: A0A8B7WZ07
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:CXHXorf23
gene id: 30608:CXHXorf23
uniprot id: A0A8B7HQH7
uniprot id: A0A8B7HQI4
uniprot id: A0A8B7HSB5
uniprot id: A0A8B7X0C7
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

30608:RPL35A
gene id: 30608:RPL35A
uniprot id: A0A8B7HG76
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

30608:POFUT1
gene id: 30608:POFUT1
uniprot id: A0A8B7FP60
uniprot id: A0A8B7FPE0
uniprot id: A0A8C5V3I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 65 family.
messages: Endoplasmic reticulum

30608:LOC109730745
gene id: 30608:LOC109730745
uniprot id: A0A8B7X5R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

30608:LOC105885935
gene id: 30608:LOC105885935
uniprot id: A0A8B7I8Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

30608:STARD3NL
gene id: 30608:STARD3NL
uniprot id: A0A8C5W8S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Membrane

30608:VDR
gene id: 30608:VDR
uniprot id: A0A8B7FMY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Cytoplasm
messages: Nucleus

30608:HOXD8
gene id: 30608:HOXD8
uniprot id: A0A8B7FJT8
uniprot id: A0A8B7FK12
uniprot id: A0A8C5Y2L1
names: Subcellular Location Annotation
messages: Nucleus

30608:SEMA4A
gene id: 30608:SEMA4A
uniprot id: A0A8B7GKH8
names: Similarity
messages: Belongs to the semaphorin family.

30608:HHEX
gene id: 30608:HHEX
uniprot id: A0A8B7GFT9
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105884092
gene id: 30608:LOC105884092
uniprot id: A0A8B7X4F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:GTF2F1
gene id: 30608:GTF2F1
uniprot id: A0A8B7G5F5
uniprot id: A0A8B7G604
uniprot id: A0A8B7WVM3
uniprot id: A0A8B7WVN1
uniprot id: A0A8C5UT97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

30608:INPP5D
gene id: 30608:INPP5D
uniprot id: A0A8B7I7Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane

30608:BRINP3
gene id: 30608:BRINP3
uniprot id: A0A8C5XWI5
names: Similarity
messages: Belongs to the BRINP family.

30608:TMEM231
gene id: 30608:TMEM231
uniprot id: A0A8B7GWU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM231 family.
messages: Membrane
messages: Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling.
messages: cilium membrane

30608:LOC105863167
gene id: 30608:LOC105863167
uniprot id: A0A8B7FBA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:DRGX
gene id: 30608:DRGX
uniprot id: A0A8C5Y124
names: Subcellular Location Annotation
messages: Nucleus

30608:TBCC
gene id: 30608:TBCC
uniprot id: A0A8B7GYG0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCC family.
messages: Cytoplasm
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.

30608:SERPINA5
gene id: 30608:SERPINA5
uniprot id: A0A8C5V477
names: Similarity
messages: Belongs to the serpin family.

30608:IFT57
gene id: 30608:IFT57
uniprot id: A0A8B7H7X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT57 family.
messages: cilium basal body

30608:RGN
gene id: 30608:RGN
uniprot id: A0A8B7FAV8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm
messages: Monomer.

30608:SAMD8
gene id: 30608:SAMD8
uniprot id: A0A8B7FR99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

30608:NKX1-1
gene id: 30608:NKX1-1
uniprot id: A0A8B7HNX3
names: Subcellular Location Annotation
messages: Nucleus

30608:MACF1
gene id: 30608:MACF1
uniprot id: A0A8B7HEA5
uniprot id: A0A8B7HEA6
uniprot id: A0A8B7HEB0
uniprot id: A0A8B7HEB2
uniprot id: A0A8B7HEB7
uniprot id: A0A8B7HEB9
uniprot id: A0A8B7HEC2
uniprot id: A0A8B7HEC5
uniprot id: A0A8B7HEC6
uniprot id: A0A8B7HEC7
uniprot id: A0A8B7HED0
uniprot id: A0A8B7HED1
uniprot id: A0A8B7HED3
uniprot id: A0A8B7HED7
uniprot id: A0A8B7HEE2
uniprot id: A0A8B7HEE8
uniprot id: A0A8B7HEN3
uniprot id: A0A8B7HEP0
uniprot id: A0A8B7HEP8
uniprot id: A0A8B7HEQ4
uniprot id: A0A8B7HER1
uniprot id: A0A8B7HGY4
uniprot id: A0A8B7HGZ0
uniprot id: A0A8B7HGZ5
uniprot id: A0A8B7HH04
uniprot id: A0A8B7HH09
uniprot id: A0A8B7WKJ3
uniprot id: A0A8B7WKJ7
uniprot id: A0A8B7WKL2
uniprot id: A0A8B7WKL4
uniprot id: A0A8B7WKM6
uniprot id: A0A8B7WKN2
uniprot id: A0A8B7WKN7
uniprot id: A0A8B7WKP6
uniprot id: A0A8B7WL95
names: Subcellular Location Annotation
messages: cytoskeleton

30608:LOC105882016
gene id: 30608:LOC105882016
uniprot id: A0A8B7HP44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

30608:CMPK2
gene id: 30608:CMPK2
uniprot id: A0A8B7G9U1
names: Similarity
messages: Belongs to the thymidylate kinase family.

30608:HTR1E
gene id: 30608:HTR1E
uniprot id: A0A8B7FE02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NF2
gene id: 30608:NF2
uniprot id: A0A8B7G9W9
uniprot id: A0A8B7G9X6
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

30608:OSGEP
gene id: 30608:OSGEP
uniprot id: A0A8B7FID1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleus

30608:TMCO3
gene id: 30608:TMCO3
uniprot id: A0A8B7GEZ6
uniprot id: A0A8B7GF46
names: Subcellular Location Annotation
messages: Membrane

30608:CES3
gene id: 30608:CES3
uniprot id: A0A8B7ESI0
uniprot id: A0A8B7ESI1
uniprot id: A0A8B7ESI3
uniprot id: A0A8B7EUB4
uniprot id: A0A8B7EUB9
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

30608:ACLY
gene id: 30608:ACLY
uniprot id: A0A8B7GES0
uniprot id: A0A8B7GF83
uniprot id: A0A8B7GFM0
uniprot id: A0A8C5VNM4
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
messages: In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.

30608:RSPH3
gene id: 30608:RSPH3
uniprot id: A0A8B7G0R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flagellar radial spoke RSP3 family.
messages: flagellum axoneme

30608:EBF2
gene id: 30608:EBF2
uniprot id: A0A8B7WS47
uniprot id: A0A8B7WS55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

30608:HAO2
gene id: 30608:HAO2
uniprot id: A0A8C5XVI8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

30608:IFNG
gene id: 30608:IFNG
uniprot id: A0A8C5UTE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II (or gamma) interferon family.
messages: Homodimer.
messages: Secreted
messages: Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation. Primarily signals through the JAK-STAT pathway after interaction with its receptor IFNGR1 to affect gene regulation. Upon IFNG binding, IFNGR1 intracellular domain opens out to allow association of downstream signaling components JAK2, JAK1 and STAT1, leading to STAT1 activation, nuclear translocation and transcription of IFNG-regulated genes. Many of the induced genes are transcription factors such as IRF1 that are able to further drive regulation of a next wave of transcription. Plays a role in class I antigen presentation pathway by inducing a replacement of catalytic proteasome subunits with immunoproteasome subunits. In turn, increases the quantity, quality, and repertoire of peptides for class I MHC loading. Increases the efficiency of peptide generation also by inducing the expression of activator PA28 that associates with the proteasome and alters its proteolytic cleavage preference. Up-regulates as well MHC II complexes on the cell surface by promoting expression of several key molecules such as cathepsins B/CTSB, H/CTSH, and L/CTSL. Participates in the regulation of hematopoietic stem cells during development and under homeostatic conditions by affecting their development, quiescence, and differentiation.

30608:MED12L
gene id: 30608:MED12L
uniprot id: A0A8B7HL82
uniprot id: A0A8B7HL90
uniprot id: A0A8B7HL91
uniprot id: A0A8B7HL93
uniprot id: A0A8B7HMI0
uniprot id: A0A8B7HMI6
uniprot id: A0A8B7HNQ5
uniprot id: A0A8B7HNR4
uniprot id: A0A8B7HNR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 12 family.
messages: Nucleus

30608:A4GALT
gene id: 30608:A4GALT
uniprot id: A0A8B7EQ40
uniprot id: A0A8B7EQ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

30608:EXO5
gene id: 30608:EXO5
uniprot id: A0A8B7WKV0
names: Similarity
messages: Belongs to the EXO5 family.

30608:APOC1
gene id: 30608:APOC1
uniprot id: A0A8B7G3V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C1 family.
messages: Secreted

30608:CA13
gene id: 30608:CA13
uniprot id: A0A8B7X9Q8
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

30608:MMP24
gene id: 30608:MMP24
uniprot id: A0A8B7FN55
uniprot id: A0A8B7FNC9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

30608:APPL1
gene id: 30608:APPL1
uniprot id: A0A8B7WL52
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: Nucleus
messages: phagosome
messages: ruffle

30608:LOC105877658
gene id: 30608:LOC105877658
uniprot id: A0A8B7H632
uniprot id: A0A8B7H646
uniprot id: A0A8B7H651
uniprot id: A0A8B7H8H2
uniprot id: A0A8B7WNN6
uniprot id: A0A8B7WPY5
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

30608:OOEP
gene id: 30608:OOEP
uniprot id: A0A8B7I3P7
names: Similarity
messages: Belongs to the KHDC1 family.

30608:LOC105863978
gene id: 30608:LOC105863978
uniprot id: A0A8B7XF92
names: Similarity
messages: Belongs to the SZRD1 family.

30608:OCLN
gene id: 30608:OCLN
uniprot id: A0A8B7HLX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
messages: Membrane
messages: tight junction

30608:SRPRB
gene id: 30608:SRPRB
uniprot id: A0A8C5YK50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP receptor beta subunit family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:SEZ6
gene id: 30608:SEZ6
uniprot id: A0A8B7EMR2
uniprot id: A0A8B7EP79
uniprot id: A0A8C5YH91
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:GAP43
gene id: 30608:GAP43
uniprot id: A0A8B7HSR1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neuromodulin family.
messages: Cell membrane
messages: Cytoplasm
messages: Identified in a complex containing FGFR4, NCAM1, CDH2, PLCG1, FRS2, SRC, SHC1, GAP43 and CTTN. Interacts (via IQ domain) with calmodulin. Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence.
messages: Membrane
messages: Palmitoylated. Palmitoylation is essential for plasma membrane association.
messages: Perikaryon
messages: Synapse
messages: This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
messages: axon
messages: dendrite
messages: filopodium membrane
messages: growth cone membrane

30608:LOC105874714
gene id: 30608:LOC105874714
uniprot id: A0A8B7WUZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

30608:CKMT1A
gene id: 30608:CKMT1A
uniprot id: A0A8C5V5Q4
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

30608:PFKM
gene id: 30608:PFKM
uniprot id: A0A8B7X5P6
uniprot id: A0A8B7X6B2
uniprot id: A0A8B7X6B6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:EIF3I
gene id: 30608:EIF3I
uniprot id: A0A8B7GDW8
uniprot id: A0A8B7GET2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm
messages: Phosphorylated by TGF-beta type II receptor.

30608:DPF2
gene id: 30608:DPF2
uniprot id: A0A8B7H9X8
names: Similarity
messages: Belongs to the requiem/DPF family.

30608:BOK
gene id: 30608:BOK
uniprot id: A0A8B7FQT7
names: Similarity
messages: Belongs to the Bcl-2 family.

30608:LOC105864577
gene id: 30608:LOC105864577
uniprot id: A0A8B7FHS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PHTF1
gene id: 30608:PHTF1
uniprot id: A0A8B7HAY4
names: Subcellular Location Annotation
messages: Membrane

30608:ST6GALNAC3
gene id: 30608:ST6GALNAC3
uniprot id: A0A8B7HYP7
uniprot id: A0A8B7HYQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

30608:LOC105858707
gene id: 30608:LOC105858707
uniprot id: A0A8B7EQX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:APOA1
gene id: 30608:APOA1
uniprot id: A0A8B7H1F8
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

30608:TRPM7
gene id: 30608:TRPM7
uniprot id: A0A8B7G9V6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: In the C-terminal section; belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.
messages: Membrane

30608:FAM162B
gene id: 30608:FAM162B
uniprot id: A0A8B7FKW3
uniprot id: A0A8B7FL16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0389 family.
messages: Membrane

30608:PTK2B
gene id: 30608:PTK2B
uniprot id: A0A8B7H3I5
uniprot id: A0A8C5XMY6
names: Subcellular Location Annotation
messages: Cell membrane
messages: cell cortex
messages: focal adhesion

30608:LSM3
gene id: 30608:LSM3
uniprot id: A0A8B7F3V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

30608:POLR2J
gene id: 30608:POLR2J
uniprot id: A0A8C6EKT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.
messages: Nucleus

30608:CLPP
gene id: 30608:CLPP
uniprot id: A0A8B7G4M4
names: Similarity
messages: Belongs to the peptidase S14 family.

30608:XRCC5
gene id: 30608:XRCC5
uniprot id: A0A8B7X782
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku80 family.
messages: Nucleus

30608:SLC9A6
gene id: 30608:SLC9A6
uniprot id: A0A8B7FH45
uniprot id: A0A8B7FH72
uniprot id: A0A8B7FIE4
uniprot id: A0A8B7WZ28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Endosome membrane
messages: Recycling endosome membrane

30608:LOC105871386
gene id: 30608:LOC105871386
uniprot id: A0A8B7GC18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105862727
gene id: 30608:LOC105862727
uniprot id: A0A8C5VCJ6
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

30608:UPK1B
gene id: 30608:UPK1B
uniprot id: A0A8B7HIR1
names: Subcellular Location Annotation
messages: Membrane

30608:RHAG
gene id: 30608:RHAG
uniprot id: A0A8B7G2R4
uniprot id: A0A8B7X6I1
uniprot id: A0A8C5XCS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

30608:LOC105864528
gene id: 30608:LOC105864528
uniprot id: A0A8B7FIR4
names: Subcellular Location Annotation
messages: Membrane

30608:CHD6
gene id: 30608:CHD6
uniprot id: A0A8B7HIC7
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

30608:ANP32A
gene id: 30608:ANP32A
uniprot id: A0A8B7GMK9
uniprot id: A0A8C5VPF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANP32 family.
messages: Multifunctional protein that is involved in the regulation of many processes.
messages: Nucleus

30608:POMT2
gene id: 30608:POMT2
uniprot id: A0A8B7ET52
uniprot id: A0A8B7EV04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

30608:PTGDR
gene id: 30608:PTGDR
uniprot id: A0A8C5VIQ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:STX2
gene id: 30608:STX2
uniprot id: A0A8B7GIC8
uniprot id: A0A8B7GIX7
uniprot id: A0A8C5Y054
names: Similarity
messages: Belongs to the syntaxin family.

30608:SSH1
gene id: 30608:SSH1
uniprot id: A0A8B7FSL0
uniprot id: A0A8B7FT93
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

30608:GMPPA
gene id: 30608:GMPPA
uniprot id: A0A8B7ELB1
uniprot id: A0A8B7ELB3
uniprot id: A0A8B7EMN3
uniprot id: A0A8B7EMN9
uniprot id: A0A8B7ENL5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

30608:LOC105874791
gene id: 30608:LOC105874791
uniprot id: A0A8C5XUA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

30608:PELP1
gene id: 30608:PELP1
uniprot id: A0A8B7HDA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RIX1/PELP1 family.
messages: Cytoplasm
messages: Nucleus

30608:PPP6R2
gene id: 30608:PPP6R2
uniprot id: A0A8B7I4R9
uniprot id: A0A8B7I4S3
uniprot id: A0A8B7I5Q1
names: Similarity
messages: Belongs to the SAPS family.

30608:SPCS2
gene id: 30608:SPCS2
uniprot id: A0A8C5XQJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS2 family.
messages: Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:VPS25
gene id: 30608:VPS25
uniprot id: A0A8B7EU35
names: Similarity
messages: Belongs to the VPS25 family.

30608:VANGL1
gene id: 30608:VANGL1
uniprot id: A0A8B7G693
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

30608:LOC105856777
gene id: 30608:LOC105856777
uniprot id: A0A8B7X2A0
names: Similarity
messages: Belongs to the serpin family.

30608:LOC105883337
gene id: 30608:LOC105883337
uniprot id: A0A8B7HUU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ZAR1L
gene id: 30608:ZAR1L
uniprot id: A0A8B7FGP2
uniprot id: A0A8C5VWC0
names: Similarity
names: Subunit
messages: Belongs to the ZAR1 family.
messages: Interacts with YBX2.

30608:LOC105859234
gene id: 30608:LOC105859234
uniprot id: A0A8B7ET42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CLEC16A
gene id: 30608:CLEC16A
uniprot id: A0A8B7HQY4
uniprot id: A0A8B7HR19
uniprot id: A0A8B7HR21
uniprot id: A0A8B7HST4
uniprot id: A0A8B7HSU1
uniprot id: A0A8B7HSW5
uniprot id: A0A8B7HTD8
uniprot id: A0A8B7HTE3
uniprot id: A0A8C5YEV1
names: Similarity
messages: Belongs to the CLEC16A/gop-1 family.

30608:GCDH
gene id: 30608:GCDH
uniprot id: A0A8B7I4X6
uniprot id: A0A8C5VBG3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

30608:UTP3
gene id: 30608:UTP3
uniprot id: A0A8B7HTM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAS10 family.
messages: nucleolus

30608:LOC105862792
gene id: 30608:LOC105862792
uniprot id: A0A8B7F9Q6
names: Similarity
messages: Belongs to the MIF family.

30608:LOC105879475
gene id: 30608:LOC105879475
uniprot id: A0A8B7WY75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

30608:PRR5L
gene id: 30608:PRR5L
uniprot id: A0A8B7EKA3
uniprot id: A0A8B7X307
uniprot id: A0A8B7X4H0
names: Similarity
messages: Belongs to the PROTOR family.

30608:SNTB2
gene id: 30608:SNTB2
uniprot id: A0A8B7WSU5
names: Subcellular Location Annotation
messages: Cell junction

30608:CD34
gene id: 30608:CD34
uniprot id: A0A8C5VH55
names: Subcellular Location Annotation
messages: Membrane

30608:WDYHV1
gene id: 30608:WDYHV1
uniprot id: A0A8B7EU95
uniprot id: A0A8B7EUA1
uniprot id: A0A8B7EW94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NTAQ1 family.
messages: Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.
messages: Monomer.

30608:GJC2
gene id: 30608:GJC2
uniprot id: A0A8B7HB83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

30608:ZACN
gene id: 30608:ZACN
uniprot id: A0A8B7HBI0
names: Subcellular Location Annotation
messages: Membrane

30608:SFR1
gene id: 30608:SFR1
uniprot id: A0A8B7GS52
uniprot id: A0A8B7GSD1
uniprot id: A0A8B7GSF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFR1/MEI5 family.
messages: Nucleus

30608:GSKIP
gene id: 30608:GSKIP
uniprot id: A0A8B7I6D3
uniprot id: A0A8C5VZH2
names: Similarity
messages: Belongs to the GSKIP family.

30608:ATP2B1
gene id: 30608:ATP2B1
uniprot id: A0A8B7FKX7
uniprot id: A0A8B7FL00
uniprot id: A0A8B7FL31
uniprot id: A0A8B7FL40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:ENTPD2
gene id: 30608:ENTPD2
uniprot id: A0A8B7HQ57
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

30608:HTR2C
gene id: 30608:HTR2C
uniprot id: A0A8C6EFE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CCR8
gene id: 30608:CCR8
uniprot id: A0A8C5YIC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

30608:UNC13C
gene id: 30608:UNC13C
uniprot id: A0A8B7HLU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-13 family.
messages: Cytoplasm
messages: Membrane

30608:MTMR1
gene id: 30608:MTMR1
uniprot id: A0A8B7FJK8
uniprot id: A0A8B7FJL3
uniprot id: A0A8B7FJL5
uniprot id: A0A8B7FJP1
uniprot id: A0A8B7FJP4
uniprot id: A0A8B7FJT3
uniprot id: A0A8B7FJT7
uniprot id: A0A8B7FJU3
uniprot id: A0A8B7FL07
uniprot id: A0A8B7WZA2
uniprot id: A0A8B7X119
uniprot id: A0A8C5XHP8
uniprot id: A0A8C5Y535
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

30608:E2F3
gene id: 30608:E2F3
uniprot id: A0A8B7FK86
uniprot id: A0A8B7FKC6
uniprot id: A0A8B7FLM9
uniprot id: A0A8C5XJQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

30608:ABCD4
gene id: 30608:ABCD4
uniprot id: A0A8B7EQU0
uniprot id: A0A8B7ESI8
uniprot id: A0A8B7ESX3
names: Subcellular Location Annotation
messages: Membrane

30608:DCBLD2
gene id: 30608:DCBLD2
uniprot id: A0A8B7ETN0
uniprot id: A0A8B7ETN7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:FMO4
gene id: 30608:FMO4
uniprot id: A0A8B7X0U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane

30608:OGDHL
gene id: 30608:OGDHL
uniprot id: A0A8B7EXI8
uniprot id: A0A8B7EZD9
uniprot id: A0A8B7WLC7
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

30608:MMP7
gene id: 30608:MMP7
uniprot id: A0A8B7GRY0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

30608:NEIL3
gene id: 30608:NEIL3
uniprot id: A0A8B7GSA9
uniprot id: A0A8B7GSJ8
uniprot id: A0A8B7GSK9
uniprot id: A0A8B7GU02
names: Similarity
messages: Belongs to the FPG family.

30608:SIKE1
gene id: 30608:SIKE1
uniprot id: A0A8C5VY35
names: Similarity
messages: Belongs to the SIKE family.

30608:LOC105858695
gene id: 30608:LOC105858695
uniprot id: A0A8C5Y8I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:GFRA3
gene id: 30608:GFRA3
uniprot id: A0A8B7WRR7
names: Similarity
messages: Belongs to the GDNFR family.

30608:ALG6
gene id: 30608:ALG6
uniprot id: A0A8B7X9Z5
uniprot id: A0A8B7XBN8
uniprot id: A0A8C5UKY6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:C17H1orf101
gene id: 30608:C17H1orf101
uniprot id: A0A8B7FEP9
uniprot id: A0A8B7FFN8
names: Similarity
messages: Belongs to the CATSPERD family.

30608:LOC105871379
gene id: 30608:LOC105871379
uniprot id: A0A8B7GD17
names: Subcellular Location Annotation
messages: Membrane

30608:PPP1R12B
gene id: 30608:PPP1R12B
uniprot id: A0A8B7EWP9
uniprot id: A0A8B7EWQ4
uniprot id: A0A8B7EWQ5
uniprot id: A0A8B7EWQ6
uniprot id: A0A8B7EYQ1
uniprot id: A0A8C5VDZ0
uniprot id: A0A8C5XYW2
uniprot id: A0A8C5YB24
names: Subcellular Location Annotation
names: Subunit
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.
messages: stress fiber

30608:CPT1C
gene id: 30608:CPT1C
uniprot id: A0A8B7FMF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

30608:LOC105861269
gene id: 30608:LOC105861269
uniprot id: A0A8B7X565
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PCK2
gene id: 30608:PCK2
uniprot id: A0A8B7FR65
names: Similarity
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Monomer.

30608:RPS6KB2
gene id: 30608:RPS6KB2
uniprot id: A0A8B7FUS4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

30608:DNAJC10
gene id: 30608:DNAJC10
uniprot id: A0A8B7HVA2
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.
messages: Endoplasmic reticulum lumen

30608:LOC105883470
gene id: 30608:LOC105883470
uniprot id: A0A8B7HVE0
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105859732
gene id: 30608:LOC105859732
uniprot id: A0A8B7EVF1
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:CA11
gene id: 30608:CA11
uniprot id: A0A8C5V6N6
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Does not have a catalytic activity.

30608:TIMM17A
gene id: 30608:TIMM17A
uniprot id: A0A8B7EWY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

30608:SPC25
gene id: 30608:SPC25
uniprot id: A0A8B7HIZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

30608:LOC105859857
gene id: 30608:LOC105859857
uniprot id: A0A8C5YA29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

30608:ST3GAL2
gene id: 30608:ST3GAL2
uniprot id: A0A8C5VTN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

30608:CD244
gene id: 30608:CD244
uniprot id: A0A8C5XEB7
names: Subcellular Location Annotation
messages: Membrane

30608:FGF6
gene id: 30608:FGF6
uniprot id: A0A8C5W345
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

30608:JAG2
gene id: 30608:JAG2
uniprot id: A0A8B7F3M6
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

30608:GNAI2
gene id: 30608:GNAI2
uniprot id: A0A8B7GTY8
names: Similarity
messages: Belongs to the G-alpha family. G(i/o/t/z) subfamily.

30608:OPN1LW
gene id: 30608:OPN1LW
uniprot id: A0A8B7FU35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

30608:MAT1A
gene id: 30608:MAT1A
uniprot id: A0A8B7G6T2
uniprot id: A0A8B7G7B9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

30608:MIGA1
gene id: 30608:MIGA1
uniprot id: A0A8B7HXI4
names: Similarity
messages: Belongs to the mitoguardin family.

30608:WDFY2
gene id: 30608:WDFY2
uniprot id: A0A8B7HKQ0
uniprot id: A0A8C5XXI7
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

30608:SSBP3
gene id: 30608:SSBP3
uniprot id: A0A8B7FAF9
uniprot id: A0A8B7FAH1
uniprot id: A0A8C5VU79
uniprot id: A0A8C5XS29
names: Subcellular Location Annotation
messages: Nucleus

30608:SLC6A3
gene id: 30608:SLC6A3
uniprot id: A0A8B7H0I7
uniprot id: A0A8B7H2J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily.
messages: Cell membrane
messages: Membrane
messages: axon
messages: neuron projection

30608:BUD13
gene id: 30608:BUD13
uniprot id: A0A8B7GZJ4
uniprot id: A0A8B7GZJ6
names: Similarity
messages: Belongs to the CWC26 family.

30608:LOC105860999
gene id: 30608:LOC105860999
uniprot id: A0A8B7F1H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP9 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm

30608:SLC17A5
gene id: 30608:SLC17A5
uniprot id: A0A8B7I0V5
uniprot id: A0A8C5VVQ7
names: Subcellular Location Annotation
messages: Membrane

30608:TNNI3
gene id: 30608:TNNI3
uniprot id: A0A8C5VV82
names: Function
names: Similarity
messages: Belongs to the troponin I family.
messages: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

30608:TUT1
gene id: 30608:TUT1
uniprot id: A0A8B7HAF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Nucleus speckle
messages: nucleolus

30608:SH2B1
gene id: 30608:SH2B1
uniprot id: A0A8B7FY05
uniprot id: A0A8B7FY18
uniprot id: A0A8B7FY23
uniprot id: A0A8B7FY61
uniprot id: A0A8C5V5E3
names: Similarity
messages: Belongs to the SH2B adapter family.

30608:EXOG
gene id: 30608:EXOG
uniprot id: A0A8B7FS25
uniprot id: A0A8B7FT40
uniprot id: A0A8B7X1R7
uniprot id: A0A8C6ELI3
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

30608:LOC105879083
gene id: 30608:LOC105879083
uniprot id: A0A8B7WYU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft

30608:MRPL50
gene id: 30608:MRPL50
uniprot id: A0A8B7GND6
uniprot id: A0A8C5Y6R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL50 family.
messages: Mitochondrion

30608:LOC105881477
gene id: 30608:LOC105881477
uniprot id: A0A8B7HM12
names: Subcellular Location Annotation
messages: Cajal body
messages: Perikaryon
messages: Z line
messages: neuron projection

30608:GUCY1A2
gene id: 30608:GUCY1A2
uniprot id: A0A8B7FR44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

30608:HCRT
gene id: 30608:HCRT
uniprot id: A0A8C5XDP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the orexin family.
messages: Endoplasmic reticulum
messages: Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested.
messages: Rough endoplasmic reticulum
messages: Synapse
messages: Vesicle

30608:ZFPL1
gene id: 30608:ZFPL1
uniprot id: A0A8C5UQ34
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZFPL1 family.
messages: Interacts with GOLGA2/GM130.
messages: Membrane
messages: Required for cis-Golgi integrity and efficient ER to Golgi transport.
messages: The B box-type and RING-type zinc fingers although degenerate play a central role in function of the protein.
messages: cis-Golgi network membrane

30608:ABCA8
gene id: 30608:ABCA8
uniprot id: A0A8B7F574
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105868763
gene id: 30608:LOC105868763
uniprot id: A0A8B7G0C1
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

30608:UBE4B
gene id: 30608:UBE4B
uniprot id: A0A8B7X1Z4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm
messages: The U-box domain is required for the ubiquitin protein ligase activity.
messages: Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. Also functions as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. Mediates 'Lys-48'-linked polyubiquitination of substrates.

30608:SLC25A19
gene id: 30608:SLC25A19
uniprot id: A0A8B7HBS2
uniprot id: A0A8B7HEE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:KIAA1024
gene id: 30608:KIAA1024
uniprot id: A0A8B7XCB8
names: Similarity
messages: Belongs to the MINAR family.

30608:NOP56
gene id: 30608:NOP56
uniprot id: A0A8B7FQ82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus
messages: nucleoplasm

30608:FAM92B
gene id: 30608:FAM92B
uniprot id: A0A8B7GBY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CIBAR family.
messages: centriole
messages: cilium basal body

30608:FER
gene id: 30608:FER
uniprot id: A0A8B7I4E8
uniprot id: A0A8B7I6F2
uniprot id: A0A8C5V808
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

30608:HS2ST1
gene id: 30608:HS2ST1
uniprot id: A0A8B7WST9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:MKNK2
gene id: 30608:MKNK2
uniprot id: A0A8C5XMN0
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:CENPN
gene id: 30608:CENPN
uniprot id: A0A8C5VM50
names: Similarity
messages: Belongs to the CENP-N/CHL4 family.

30608:EEF1A1
gene id: 30608:EEF1A1
uniprot id: A0A8B7X6D1
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

30608:SEMA3F
gene id: 30608:SEMA3F
uniprot id: A0A8C5XES4
uniprot id: A0A8C6EJE1
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:SRMS
gene id: 30608:SRMS
uniprot id: A0A8B7GXR9
uniprot id: A0A8B7GXT3
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

30608:ARHGEF12
gene id: 30608:ARHGEF12
uniprot id: A0A8B7GZ28
uniprot id: A0A8B7GZ30
uniprot id: A0A8B7GZ33
uniprot id: A0A8B7GZ41
uniprot id: A0A8B7GZ81
uniprot id: A0A8C5Y5M9
uniprot id: A0A8C5Y5Z5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

30608:RCAN3
gene id: 30608:RCAN3
uniprot id: A0A8C5YA38
names: Similarity
messages: Belongs to the RCAN family.

30608:HOXD12
gene id: 30608:HOXD12
uniprot id: A0A8C5UNB9
names: Subcellular Location Annotation
messages: Nucleus

30608:KDM3A
gene id: 30608:KDM3A
uniprot id: A0A8B7H107
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM2 histone demethylase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.
messages: Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.
messages: Nucleus
messages: The JmjC domain and the C6-type zinc-finger are required for the demethylation activity.

30608:TACSTD2
gene id: 30608:TACSTD2
uniprot id: A0A8B7HTP9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:ICMT
gene id: 30608:ICMT
uniprot id: A0A8C5XFH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:GCK
gene id: 30608:GCK
uniprot id: A0A8B7ERA0
uniprot id: A0A8C5VXM3
names: Similarity
messages: Belongs to the hexokinase family.

30608:PCNX4
gene id: 30608:PCNX4
uniprot id: A0A8B7HV93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

30608:JMJD1C
gene id: 30608:JMJD1C
uniprot id: A0A8B7G787
uniprot id: A0A8B7G794
uniprot id: A0A8B7G7E2
uniprot id: A0A8B7G7X0
uniprot id: A0A8B7G7X7
uniprot id: A0A8B7G8C9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM2 histone demethylase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.
messages: Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.
messages: Nucleus
messages: The JmjC domain and the C6-type zinc-finger are required for the demethylation activity.

30608:RPL10A
gene id: 30608:RPL10A
uniprot id: A0A8B7F474
uniprot id: A0A8C6EJN8
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

30608:SF3B5
gene id: 30608:SF3B5
uniprot id: A0A8B7FT63
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SF3B5 family.
messages: Component of the spliceosome B complex.
messages: Nucleus

30608:PNPLA2
gene id: 30608:PNPLA2
uniprot id: A0A8B7GPR8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:PRKCH
gene id: 30608:PRKCH
uniprot id: A0A8C5VMQ9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentiation. Associates with the cyclin CCNE1-CDK2-CDKN1B complex and inhibits CDK2 kinase activity, leading to RB1 dephosphorylation and thereby G1 arrest in keratinocytes. In association with RALA activates actin depolymerization, which is necessary for keratinocyte differentiation. In the pre-B cell receptor signaling, functions downstream of BLNK by up-regulating IRF4, which in turn activates L chain gene rearrangement. Regulates epithelial tight junctions (TJs) by phosphorylating occludin (OCLN) on threonine residues, which is necessary for the assembly and maintenance of TJs. In association with PLD2 and via TLR4 signaling, is involved in lipopolysaccharide (LPS)-induced RGS2 down-regulation and foam cell formation. Upon PMA stimulation, mediates glioblastoma cell proliferation by activating the mTOR pathway, the PI3K/AKT pathway and the ERK1-dependent phosphorylation of ELK1. Involved in the protection of glioblastoma cells from irradiation-induced apoptosis by preventing caspase-9 activation. In camptothecin-treated MCF-7 cells, regulates NF-kappa-B upstream signaling by activating IKBKB, and confers protection against DNA damage-induced apoptosis.
messages: Cytoplasm
messages: Novel PKCs (PRKCD, PRKCE, PRKCH and PRKCQ) are calcium-insensitive, but activated by diacylglycerol (DAG) and phosphatidylserine. Three specific sites; Thr-513 (activation loop of the kinase domain), Thr-656 (turn motif) and Ser-675 (hydrophobic region), need to be phosphorylated for its full activation.

30608:IGF1
gene id: 30608:IGF1
uniprot id: A0A8B7GX49
uniprot id: A0A8B7GX93
uniprot id: A0A8B7GYZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

30608:NXF1
gene id: 30608:NXF1
uniprot id: A0A8C5XPA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm
messages: nucleoplasm

30608:THRA
gene id: 30608:THRA
uniprot id: A0A8B7GF32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

30608:GRIN2C
gene id: 30608:GRIN2C
uniprot id: A0A8B7HBL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

30608:TPH1
gene id: 30608:TPH1
uniprot id: A0A8B7HIV1
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

30608:HS3ST3B1
gene id: 30608:HS3ST3B1
uniprot id: A0A8C5Y6Q4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

30608:TMEM63C
gene id: 30608:TMEM63C
uniprot id: A0A8B7EUS6
uniprot id: A0A8C5VZD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

30608:ITM2C
gene id: 30608:ITM2C
uniprot id: A0A8B7FAA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

30608:LOC105862781
gene id: 30608:LOC105862781
uniprot id: A0A8B7F9Q0
names: Similarity
names: Subunit
messages: Belongs to the GST superfamily. Theta family.
messages: Homodimer.

30608:LOC105863311
gene id: 30608:LOC105863311
uniprot id: A0A8B7FC67
names: Subcellular Location Annotation
messages: nucleoplasm

30608:MYO7B
gene id: 30608:MYO7B
uniprot id: A0A8B7EKT9
uniprot id: A0A8B7X8Q7
uniprot id: A0A8C5XJQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: cytoskeleton

30608:TMEM88B
gene id: 30608:TMEM88B
uniprot id: A0A8B7X229
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM88 family.
messages: Membrane

30608:RAP2C
gene id: 30608:RAP2C
uniprot id: A0A8C5VUI9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Palmitoylated.
messages: Recycling endosome membrane
messages: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form.

30608:C1R
gene id: 30608:C1R
uniprot id: A0A8C5VDU7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:CDK1
gene id: 30608:CDK1
uniprot id: A0A8B7WLH4
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:LOC105883391
gene id: 30608:LOC105883391
uniprot id: A0A8B7HV03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105883492
gene id: 30608:LOC105883492
uniprot id: A0A8B7HVE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SFXN3
gene id: 30608:SFXN3
uniprot id: A0A8B7GNK5
uniprot id: A0A8B7GNS6
uniprot id: A0A8B7GPL9
uniprot id: A0A8C5XXS0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

30608:AASDHPPT
gene id: 30608:AASDHPPT
uniprot id: A0A8C5VH87
names: Similarity
messages: Belongs to the P-Pant transferase superfamily. AcpS family.

30608:C5H11orf70
gene id: 30608:C5H11orf70
uniprot id: A0A8C6EHI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP300 family.
messages: Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. May play a role in outer and inner dynein arm assembly.
messages: Cytoplasm

30608:NEK7
gene id: 30608:NEK7
uniprot id: A0A8C5VCV9
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:ACKR2
gene id: 30608:ACKR2
uniprot id: A0A8B7GRJ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

30608:GJB1
gene id: 30608:GJB1
uniprot id: A0A654IC93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins. Interacts with CNST.
messages: Belongs to the connexin family. Beta-type (group I) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

30608:SFXN4
gene id: 30608:SFXN4
uniprot id: A0A8B7ELA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane

30608:SLC17A6
gene id: 30608:SLC17A6
uniprot id: A0A8B7EAK1
names: Subcellular Location Annotation
messages: Membrane

30608:C8H2orf61
gene id: 30608:C8H2orf61
uniprot id: A0A8B7FQD5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:FOXJ1
gene id: 30608:FOXJ1
uniprot id: A0A8B7HBY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FOXJ1 family.
messages: Nucleus

30608:CLIC3
gene id: 30608:CLIC3
uniprot id: A0A8B7HRY5
uniprot id: A0A8C5VUZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Membrane

30608:SEC24B
gene id: 30608:SEC24B
uniprot id: A0A8B7WXT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

30608:POP7
gene id: 30608:POP7
uniprot id: A0A8C5XS73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone-like Alba family.
messages: Component of nuclear RNase P and RNase MRP complexes. RNase P consists of a catalytic RNA moiety and 10 different protein chains; POP1, POP4, POP5, POP7, RPP14, RPP21, RPP25, RPP30, RPP38 and RPP40. Within the RNase P complex, POP1, POP7 and RPP25 form the 'finger' subcomplex, POP5, RPP14, RPP40 and homodimeric RPP30 form the 'palm' subcomplex, and RPP21, POP4 and RPP38 form the 'wrist' subcomplex. All subunits of the RNase P complex interact with the catalytic RNA. Several subunits of RNase P are also part of the RNase MRP complex. RNase MRP consists of a catalytic RNA moiety and about 8 protein subunits; POP1, POP7, RPP25, RPP30, RPP38, RPP40 and possibly also POP4 and POP5. Interacts with SMN1. POP7 forms a heterodimer with RPP25 that binds to the P3 stem loop of the catalytic RNA.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
messages: Cytoplasmic granule
messages: nucleolus

30608:KIAA2022
gene id: 30608:KIAA2022
uniprot id: A0A8B7FC61
uniprot id: A0A8B7WYW5
names: Subcellular Location Annotation
messages: Nucleus

30608:IDH2
gene id: 30608:IDH2
uniprot id: A0A8B7G8M5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Homodimer.

30608:WAPL
gene id: 30608:WAPL
uniprot id: A0A8B7HYX7
uniprot id: A0A8B7HYY0
names: Similarity
messages: Belongs to the WAPL family.

30608:CKB
gene id: 30608:CKB
uniprot id: A0A8C5V0J3
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

30608:OPN4
gene id: 30608:OPN4
uniprot id: A0A8B7HYX8
uniprot id: A0A8C5V143
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:TOR2A
gene id: 30608:TOR2A
uniprot id: A0A8B7GVE1
uniprot id: A0A8B7GVK2
uniprot id: A0A8B7GX66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Endoplasmic reticulum lumen

30608:PIGX
gene id: 30608:PIGX
uniprot id: A0A8B7HFH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGX family.
messages: Endoplasmic reticulum membrane
messages: Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis.

30608:PDPR
gene id: 30608:PDPR
uniprot id: A0A8B7GWL0
uniprot id: A0A8B7WS02
names: Similarity
messages: Belongs to the GcvT family.

30608:RIMKLA
gene id: 30608:RIMKLA
uniprot id: A0A8B7F7T4
names: Similarity
messages: Belongs to the RimK family.

30608:LOC105882208
gene id: 30608:LOC105882208
uniprot id: A0A8B7HRK3
names: Subcellular Location Annotation
messages: Membrane

30608:RHBDF1
gene id: 30608:RHBDF1
uniprot id: A0A8B7EFB4
uniprot id: A0A8B7EFV0
uniprot id: A0A8B7EG46
uniprot id: A0A8B7WNW7
uniprot id: A0A8C5XDC1
uniprot id: A0A8C5Y215
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

30608:KCNMA1
gene id: 30608:KCNMA1
uniprot id: A0A8B7WL81
uniprot id: A0A8B7WL85
uniprot id: A0A8B7WL91
uniprot id: A0A8B7WL94
uniprot id: A0A8B7WL97
uniprot id: A0A8B7WL99
uniprot id: A0A8B7WLA0
uniprot id: A0A8B7WLA4
uniprot id: A0A8B7WLA5
uniprot id: A0A8B7WLA9
uniprot id: A0A8B7WLB1
uniprot id: A0A8B7WLB2
uniprot id: A0A8B7WLB8
uniprot id: A0A8B7WLC5
uniprot id: A0A8B7WLD0
uniprot id: A0A8B7WLD1
uniprot id: A0A8B7WLD5
uniprot id: A0A8B7WLD6
uniprot id: A0A8B7WLE7
uniprot id: A0A8B7WLF3
uniprot id: A0A8B7WLF8
uniprot id: A0A8B7WLG4
uniprot id: A0A8B7WM63
uniprot id: A0A8B7WM78
uniprot id: A0A8B7WM84
uniprot id: A0A8B7WM90
uniprot id: A0A8C5XZE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa1.1/KCNMA1 sub-subfamily.
messages: Membrane

30608:NCAPH2
gene id: 30608:NCAPH2
uniprot id: A0A8B7I2N0
uniprot id: A0A8B7I2N4
uniprot id: A0A8B7I2N6
uniprot id: A0A8B7I4Q6
uniprot id: A0A8B7I5N2
names: Similarity
messages: Belongs to the CND2 H2 (condensin-2 subunit 2) family.

30608:LOC105883467
gene id: 30608:LOC105883467
uniprot id: A0A8B7HVB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TAS2R38
gene id: 30608:TAS2R38
uniprot id: I0CKF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane
messages: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.

30608:NGFR
gene id: 30608:NGFR
uniprot id: A0A8B7I324
uniprot id: A0A8B7I624
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105869687
gene id: 30608:LOC105869687
uniprot id: A0A8B7WW67
uniprot id: A0A8B7WW70
uniprot id: A0A8B7WWH4
uniprot id: A0A8B7WXW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

30608:GABRG2
gene id: 30608:GABRG2
uniprot id: A0A8B7FIV0
uniprot id: A0A8B7FIY9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG2 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:TMC4
gene id: 30608:TMC4
uniprot id: A0A8B7GSG9
uniprot id: A0A8B7GSR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

30608:PGS1
gene id: 30608:PGS1
uniprot id: A0A8B7WNF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

30608:LOC105866373
gene id: 30608:LOC105866373
uniprot id: A0A8B7FQ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105884939
gene id: 30608:LOC105884939
uniprot id: A0A8B7H804
uniprot id: A0A8B7H825
names: Similarity
messages: Belongs to the CENP-X/MHF2 family.

30608:MAN1A2
gene id: 30608:MAN1A2
uniprot id: A0A8B7WZ45
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

30608:C8G
gene id: 30608:C8G
uniprot id: A0A8B7HQ81
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

30608:FGF12
gene id: 30608:FGF12
uniprot id: A0A8B7H141
uniprot id: A0A8C5YHM8
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

30608:ABCC3
gene id: 30608:ABCC3
uniprot id: A0A8B7I399
uniprot id: A0A8B7I3A5
uniprot id: A0A8B7I3B1
uniprot id: A0A8B7I5B2
uniprot id: A0A8B7I6B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

30608:TRAPPC3
gene id: 30608:TRAPPC3
uniprot id: A0A8B7GE55
uniprot id: A0A8C5W7M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

30608:GLMP
gene id: 30608:GLMP
uniprot id: A0A8B7GKF2
uniprot id: A0A8C5XNE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GLMP family.
messages: Interacts (via lumenal domain) with lysosomal protein MFSD1; the interaction starts while both proteins are still in the endoplasmic reticulum and is required for stability and lysosomal localization of MFSD1.
messages: Lysosome membrane
messages: Required to protect lysosomal transporter MFSD1 from lysosomal proteolysis and for MFSD1 lysosomal localization.

30608:NCOA1
gene id: 30608:NCOA1
uniprot id: A0A8B7HZ54
uniprot id: A0A8B7HZ66
uniprot id: A0A8C5Y9I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

30608:IZUMO3
gene id: 30608:IZUMO3
uniprot id: A0A8B7GQ99
uniprot id: A0A8B7GQF6
uniprot id: A0A8B7GRJ6
names: Similarity
messages: Belongs to the Izumo family.

30608:NDUFB10
gene id: 30608:NDUFB10
uniprot id: A0A8B7EUV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.
messages: Belongs to the complex I NDUFB10 subunit family.
messages: Mitochondrion inner membrane

30608:LOC105875329
gene id: 30608:LOC105875329
uniprot id: A0A8B7GW24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:UHRF2
gene id: 30608:UHRF2
uniprot id: A0A8B7EGX7
uniprot id: A0A8C5VS53
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Multi domain E3 ubiquitin ligase that also plays a role in DNA methylation and histone modifications.
messages: Nucleus
messages: The YDG domain mediates the interaction with histone H3.
messages: The tudor-like regions specifically recognize and bind histone H3 unmethylated at 'Arg-2' (H3R2me0), while the PHD-type zinc finger specifically recognizes and binds histone H3 trimethylated at 'Lys-9' (H3K9me3).

30608:RPL7A
gene id: 30608:RPL7A
uniprot id: A0A8C5VZX4
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

30608:NXT2
gene id: 30608:NXT2
uniprot id: A0A8B7FC88
uniprot id: A0A8B7FC94
uniprot id: A0A8B7FC98
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

30608:KCNK9
gene id: 30608:KCNK9
uniprot id: A0A8B7EAS4
uniprot id: A0A8B7EAV9
uniprot id: A0A8B7EBG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane
messages: pH-dependent, voltage-insensitive, background potassium channel protein.

30608:ASPHD2
gene id: 30608:ASPHD2
uniprot id: A0A8B7FSQ8
uniprot id: A0A8B7FSU2
uniprot id: A0A8C5XE44
names: Similarity
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

30608:CNGA4
gene id: 30608:CNGA4
uniprot id: A0A8B7HVA8
uniprot id: A0A8B7HVB6
uniprot id: A0A8B7HXG1
names: Subcellular Location Annotation
messages: Membrane

30608:RPL13
gene id: 30608:RPL13
uniprot id: A0A8B7HT45
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

30608:TYMP
gene id: 30608:TYMP
uniprot id: A0A8B7I2M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Homodimer.

30608:ACAD11
gene id: 30608:ACAD11
uniprot id: A0A8B7GHM6
uniprot id: A0A8B7GHM7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

30608:LOC109730287
gene id: 30608:LOC109730287
uniprot id: A0A8B7WZY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.
messages: Virion

30608:PIGN
gene id: 30608:PIGN
uniprot id: A0A8B7H1E2
uniprot id: A0A8B7H1E9
uniprot id: A0A8B7H3F9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:FOXO6
gene id: 30608:FOXO6
uniprot id: A0A8B7WL60
names: Subcellular Location Annotation
messages: Nucleus

30608:POLR2C
gene id: 30608:POLR2C
uniprot id: A0A8C5Y5D8
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

30608:LOC105883332
gene id: 30608:LOC105883332
uniprot id: A0A8B7HUU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TMEM161A
gene id: 30608:TMEM161A
uniprot id: A0A8B7ERN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

30608:FASN
gene id: 30608:FASN
uniprot id: A0A8B7WMW8
names: Function
messages: Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain.

30608:CREM
gene id: 30608:CREM
uniprot id: A0A8B7GF12
names: Subcellular Location Annotation
messages: Nucleus

30608:KIFC3
gene id: 30608:KIFC3
uniprot id: A0A8B7EVS8
uniprot id: A0A8B7EVS9
uniprot id: A0A8B7EVT2
uniprot id: A0A8B7EVU0
uniprot id: A0A8B7EXR3
uniprot id: A0A8B7EXR8
uniprot id: A0A8B7EXS8
uniprot id: A0A8B7WRW9
uniprot id: A0A8C5W169
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:SLCO1B3
gene id: 30608:SLCO1B3
uniprot id: A0A8B7X6M2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:LOC105886004
gene id: 30608:LOC105886004
uniprot id: A0A8B7I755
uniprot id: A0A8B7I970
uniprot id: A0A8B7IAH4
names: Similarity
messages: Belongs to the MHC class II family.

30608:LOC105879634
gene id: 30608:LOC105879634
uniprot id: A0A8B7HEL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

30608:KRT1
gene id: 30608:KRT1
uniprot id: A0A8B7GDD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

30608:LOC105884648
gene id: 30608:LOC105884648
uniprot id: A0A8C5YBS5
names: Similarity
messages: Belongs to the KHDC1 family.

30608:ELOVL7
gene id: 30608:ELOVL7
uniprot id: A0A8B7H441
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL7 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate to the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:AHDC1
gene id: 30608:AHDC1
uniprot id: A0A8B7FD72
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105883835
gene id: 30608:LOC105883835
uniprot id: A0A8B7HX59
names: Subcellular Location Annotation
messages: Membrane

30608:FAM193B
gene id: 30608:FAM193B
uniprot id: A0A8B7HXA6
uniprot id: A0A8B7HXB1
uniprot id: A0A8B7HXB7
uniprot id: A0A8B7HXD1
uniprot id: A0A8B7HZD8
uniprot id: A0A8B7HZE3
uniprot id: A0A8B7HZW2
uniprot id: A0A8B7HZW7
names: Similarity
messages: Belongs to the FAM193 family.

30608:LOC105884239
gene id: 30608:LOC105884239
uniprot id: A0A8B7I0U9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

30608:FLAD1
gene id: 30608:FLAD1
uniprot id: A0A8B7GLE2
uniprot id: A0A8C5UY95
names: Function
names: Similarity
messages: Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme.
messages: In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

30608:MID1IP1
gene id: 30608:MID1IP1
uniprot id: A0A8C5XSI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

30608:LOC105878655
gene id: 30608:LOC105878655
uniprot id: A0A8B7HAR0
names: Subcellular Location Annotation
messages: Secreted

30608:MLLT1
gene id: 30608:MLLT1
uniprot id: A0A8B7G4L5
uniprot id: A0A8B7G4L6
names: Subcellular Location Annotation
messages: Nucleus

30608:ACTA2
gene id: 30608:ACTA2
uniprot id: A0A8C5XCE5
names: Similarity
messages: Belongs to the actin family.

30608:NRDC
gene id: 30608:NRDC
uniprot id: A0A8B7H5H9
names: Similarity
messages: Belongs to the peptidase M16 family.

30608:DNAAF2
gene id: 30608:DNAAF2
uniprot id: A0A8C5VS77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PIH1 family. Kintoun subfamily.
messages: Cytoplasm
messages: Interacts with CFAP300. Interacts with DNAI2 and HSPA1A. Interacts with DYX1C1. Interacts with PIH1D3.
messages: Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.

30608:LOC105885508
gene id: 30608:LOC105885508
uniprot id: A0A8B7I517
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL42 family.
messages: Mitochondrion

30608:CSGALNACT2
gene id: 30608:CSGALNACT2
uniprot id: A0A8B7HC45
uniprot id: A0A8B7HES1
uniprot id: A0A8B7WL83
uniprot id: A0A8B7WM51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

30608:FAM160A1
gene id: 30608:FAM160A1
uniprot id: A0A8B7HPS2
names: Similarity
messages: Belongs to the FHIP family.

30608:B9D2
gene id: 30608:B9D2
uniprot id: A0A8B7G366
names: Subcellular Location Annotation
messages: cilium basal body

30608:FHL5
gene id: 30608:FHL5
uniprot id: A0A8B7GPE3
names: Function
names: Subcellular Location Annotation
messages: May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation-independent manner.
messages: Nucleus

30608:SLCO1A2
gene id: 30608:SLCO1A2
uniprot id: A0A8B7X5Z3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:LOC105878351
gene id: 30608:LOC105878351
uniprot id: A0A8B7H943
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.
messages: Heterodimer of FNTA and FNTB.

30608:LOC105864894
gene id: 30608:LOC105864894
uniprot id: A0A8B7HSY1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

30608:CASC1
gene id: 30608:CASC1
uniprot id: A0A8B7EJZ3
uniprot id: A0A8B7EKB0
uniprot id: A0A8B7EMC3
uniprot id: A0A8C5VH77
uniprot id: A0A8C5YHW8
names: Similarity
messages: Belongs to the DNAI7 family.

30608:CLCA4
gene id: 30608:CLCA4
uniprot id: A0A8B7F5I8
names: Similarity
messages: Belongs to the CLCR family.

30608:B3GALT2
gene id: 30608:B3GALT2
uniprot id: A0A8B7GWJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:LOC105859347
gene id: 30608:LOC105859347
uniprot id: A0A8B7WTI7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:LOC105866825
gene id: 30608:LOC105866825
uniprot id: A0A8B7FS80
names: Similarity
messages: Belongs to the SPATA31 family.

30608:ENTPD7
gene id: 30608:ENTPD7
uniprot id: A0A8C5V457
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

30608:LOC105864525
gene id: 30608:LOC105864525
uniprot id: A0A8B7FHF1
names: Function
names: Similarity
messages: Belongs to the GDNFR family.
messages: Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.

30608:MTFP1
gene id: 30608:MTFP1
uniprot id: A0A8C5V189
names: Similarity
messages: Belongs to the MTFP1 family.

30608:CCDC130
gene id: 30608:CCDC130
uniprot id: A0A8B7I4Q5
names: Similarity
messages: Belongs to the CWC16 family.

30608:MRPS2
gene id: 30608:MRPS2
uniprot id: A0A8B7HJH9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

30608:TSC22D1
gene id: 30608:TSC22D1
uniprot id: A0A8B7HKY9
uniprot id: A0A8B7HM66
uniprot id: A0A8B7XFZ9
uniprot id: A0A8C5VLF2
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

30608:MTFMT
gene id: 30608:MTFMT
uniprot id: A0A8B7X3E0
names: Similarity
messages: Belongs to the Fmt family.

30608:LOC105883422
gene id: 30608:LOC105883422
uniprot id: A0A8B7HV21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ASXL3
gene id: 30608:ASXL3
uniprot id: A0A8B7HKK6
uniprot id: A0A8B7HKK9
uniprot id: A0A8B7HKL4
uniprot id: A0A8B7HKL8
uniprot id: A0A8B7HLT7
uniprot id: A0A8B7HLU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asx family.
messages: Nucleus

30608:SMC1B
gene id: 30608:SMC1B
uniprot id: A0A8B7FVF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

30608:SCML2
gene id: 30608:SCML2
uniprot id: A0A8B7HQL7
uniprot id: A0A8B7HQM8
uniprot id: A0A8B7HT03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

30608:KCNS2
gene id: 30608:KCNS2
uniprot id: A0A8B7G5E6
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105864053
gene id: 30608:LOC105864053
uniprot id: A0A8B7FFW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

30608:C6H6orf89
gene id: 30608:C6H6orf89
uniprot id: A0A8B7F2Z8
uniprot id: A0A8B7F3Z1
uniprot id: A0A8B7F3Z3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

30608:LOC105858689
gene id: 30608:LOC105858689
uniprot id: A0A8C5XTV1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:NEK9
gene id: 30608:NEK9
uniprot id: A0A8B7ERE3
uniprot id: A0A8B7ERH0
uniprot id: A0A8B7ETH3
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

30608:ADIPOR2
gene id: 30608:ADIPOR2
uniprot id: A0A8B7F4R6
uniprot id: A0A8B7F4S2
uniprot id: A0A8B7F4S6
uniprot id: A0A8B7F4T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

30608:ACSF3
gene id: 30608:ACSF3
uniprot id: A0A8C5W4M2
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

30608:NDUFAB1
gene id: 30608:NDUFAB1
uniprot id: A0A8C5UTQ4
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

30608:LOC105880103
gene id: 30608:LOC105880103
uniprot id: A0A8B7HJD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

30608:CALB2
gene id: 30608:CALB2
uniprot id: A0A8B7ESJ9
names: Function
names: Similarity
messages: Belongs to the calbindin family.
messages: Calretinin is a calcium-binding protein which is abundant in auditory neurons.

30608:LOC109731386
gene id: 30608:LOC109731386
uniprot id: A0A8B7XE62
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

30608:BAZ2A
gene id: 30608:BAZ2A
uniprot id: A0A8B7FL93
uniprot id: A0A8B7FMJ8
uniprot id: A0A8B7FML6
uniprot id: A0A8B7FMM5
uniprot id: A0A8B7FMM9
names: Similarity
messages: Belongs to the WAL family.

30608:LOC105882230
gene id: 30608:LOC105882230
uniprot id: A0A8B7HPW9
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

30608:LOC105866496
gene id: 30608:LOC105866496
uniprot id: A0A8B7FRT6
names: Similarity
messages: Belongs to the SPATA31 family.

30608:RPRD2
gene id: 30608:RPRD2
uniprot id: A0A8B7GJH3
names: Similarity
messages: Belongs to the UPF0400 (RTT103) family.

30608:EIF4G1
gene id: 30608:EIF4G1
uniprot id: A0A8B7ED69
uniprot id: A0A8B7EDR0
uniprot id: A0A8B7EDT8
uniprot id: A0A8B7EFT2
uniprot id: A0A8B7EFT7
uniprot id: A0A8B7X335
uniprot id: A0A8B7X4U9
uniprot id: A0A8C5YGE0
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

30608:SH3GL1
gene id: 30608:SH3GL1
uniprot id: A0A8B7GNM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

30608:TMEM200B
gene id: 30608:TMEM200B
uniprot id: A0A8B7FCM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

30608:LOC105883395
gene id: 30608:LOC105883395
uniprot id: A0A8B7HX58
names: Subcellular Location Annotation
messages: Membrane

30608:GDA
gene id: 30608:GDA
uniprot id: A0A8B7GSW8
uniprot id: A0A8B7XCK2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

30608:SLC35E3
gene id: 30608:SLC35E3
uniprot id: A0A8B7HK90
names: Subcellular Location Annotation
messages: Membrane

30608:DCLRE1A
gene id: 30608:DCLRE1A
uniprot id: A0A8B7GWB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

30608:DGKG
gene id: 30608:DGKG
uniprot id: A0A8B7X4S3
uniprot id: A0A8B7X501
uniprot id: A0A8B7X504
uniprot id: A0A8C5YHT5
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

30608:KHDRBS1
gene id: 30608:KHDRBS1
uniprot id: A0A8B7GDY7
names: Similarity
messages: Belongs to the KHDRBS family.

30608:CLRN1
gene id: 30608:CLRN1
uniprot id: A0A8B7HL33
uniprot id: A0A8B7HL34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

30608:CLDN18
gene id: 30608:CLDN18
uniprot id: A0A8C5YGU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

30608:FGFR4
gene id: 30608:FGFR4
uniprot id: A0A8B7WYQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Membrane

30608:MPPE1
gene id: 30608:MPPE1
uniprot id: A0A8B7F195
uniprot id: A0A8B7WRK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallophosphoesterase superfamily. MPPE1 family.
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Interacts with GPI-anchor proteins. Interacts with TMED10.
messages: Membrane
messages: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.
messages: cis-Golgi network membrane

30608:VRTN
gene id: 30608:VRTN
uniprot id: A0A8B7EW72
names: Similarity
messages: Belongs to the vertnin family.

30608:MYO7A
gene id: 30608:MYO7A
uniprot id: A0A8B7EYE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: cytoskeleton

30608:LOC109731122
gene id: 30608:LOC109731122
uniprot id: A0A8B7XBY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase e subunit family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

30608:CHRNA4
gene id: 30608:CHRNA4
uniprot id: A0A8B7GY62
uniprot id: A0A8C5W1P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:LOC105857517
gene id: 30608:LOC105857517
uniprot id: A0A8B7X8T7
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:C10H9orf64
gene id: 30608:C10H9orf64
uniprot id: A0A8C5V8C3
names: Function
names: Similarity
messages: Belongs to the QNG1 protein family.
messages: Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly.

30608:HMGCS1
gene id: 30608:HMGCS1
uniprot id: A0A8C5UQ63
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

30608:LAMA5
gene id: 30608:LAMA5
uniprot id: A0A8B7GXL9
uniprot id: A0A8B7GXN3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

30608:FITM1
gene id: 30608:FITM1
uniprot id: A0A8B7FRL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIT family. FIT1 subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays an important role in the formation of lipid droplets (LDs), which are storage organelles at the center of lipid and energy homeostasis. Directly binds to diacylglycerol (DAGs) and triacylglycerol.

30608:POLD1
gene id: 30608:POLD1
uniprot id: A0A8B7WWD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

30608:RGS9BP
gene id: 30608:RGS9BP
uniprot id: A0A8B7H320
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

30608:LOC105884164
gene id: 30608:LOC105884164
uniprot id: A0A8B7I198
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:STOML1
gene id: 30608:STOML1
uniprot id: A0A8B7F770
uniprot id: A0A8C5W0D7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

30608:ING1
gene id: 30608:ING1
uniprot id: A0A8B7FGB1
uniprot id: A0A8B7FGH0
uniprot id: A0A8B7FGH5
uniprot id: A0A8B7FHG9
uniprot id: A0A8C5VZ02
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

30608:PAX4
gene id: 30608:PAX4
uniprot id: A0A8B7I1P7
uniprot id: A0A8B7I3S4
uniprot id: A0A8B7I4K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the paired homeobox family.
messages: Interacts with KDM5B.
messages: Nucleus
messages: Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs.

30608:NTHL1
gene id: 30608:NTHL1
uniprot id: A0A8B7EUS9
uniprot id: A0A8B7EUT2
uniprot id: A0A8B7EUT5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nth/MutY family.
messages: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
messages: Binds 1 [4Fe-4S] cluster. The cluster does not appear to play a role in catalysis, but is probably involved in the proper positioning of the enzyme along the DNA strand.
messages: Interacts with YBX1.
messages: Mitochondrion
messages: Nucleus

30608:NKD1
gene id: 30608:NKD1
uniprot id: A0A8B7I191
uniprot id: A0A8B7I199
uniprot id: A0A8B7WS54
uniprot id: A0A8C5VY77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm

30608:LOC105867275
gene id: 30608:LOC105867275
uniprot id: A0A8B7FTU6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.

30608:NME6
gene id: 30608:NME6
uniprot id: A0A8B7GT97
uniprot id: A0A8B7GV13
names: Similarity
messages: Belongs to the NDK family.

30608:SLC39A10
gene id: 30608:SLC39A10
uniprot id: A0A8B7H795
uniprot id: A0A8B7H7B5
names: Subcellular Location Annotation
messages: Membrane

30608:TOM1L2
gene id: 30608:TOM1L2
uniprot id: A0A8B7F6D4
uniprot id: A0A8B7F6D6
uniprot id: A0A8B7F6E7
uniprot id: A0A8B7F6I7
names: Similarity
messages: Belongs to the TOM1 family.

30608:IFNB1
gene id: 30608:IFNB1
uniprot id: A0A8B7GQG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

30608:CYSLTR1
gene id: 30608:CYSLTR1
uniprot id: A0A8B7FPT7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:GFM2
gene id: 30608:GFM2
uniprot id: A0A8B7XE61
uniprot id: A0A8B7XEP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
messages: Mitochondrion

30608:PCNP
gene id: 30608:PCNP
uniprot id: A0A8B7HE54
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with UHRF2/NIRF.
messages: May be involved in cell cycle regulation.
messages: Nucleus

30608:LOC105883495
gene id: 30608:LOC105883495
uniprot id: A0A8B7HVF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:HGFAC
gene id: 30608:HGFAC
uniprot id: A0A8B7EF00
uniprot id: A0A8B7EGW3
uniprot id: A0A8C5XCN7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:DNAH3
gene id: 30608:DNAH3
uniprot id: A0A8B7I470
names: Similarity
messages: Belongs to the dynein heavy chain family.

30608:CCT6B
gene id: 30608:CCT6B
uniprot id: A0A8B7I4B0
uniprot id: A0A8B7I4I5
uniprot id: A0A8B7I4K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

30608:LOC105866354
gene id: 30608:LOC105866354
uniprot id: A0A8B7FRA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative pheromone receptor.

30608:PPP2R2B
gene id: 30608:PPP2R2B
uniprot id: A0A8B7H0N9
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

30608:GABRA4
gene id: 30608:GABRA4
uniprot id: A0A8C5V6L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:LCTL
gene id: 30608:LCTL
uniprot id: A0A8B7FX97
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

30608:LOC105878361
gene id: 30608:LOC105878361
uniprot id: A0A8B7H959
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

30608:LOC105881308
gene id: 30608:LOC105881308
uniprot id: A0A8B7WZ11
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Monomer.

30608:YPEL2
gene id: 30608:YPEL2
uniprot id: A0A8B7GQ60
names: Similarity
messages: Belongs to the yippee family.

30608:LOC105879208
gene id: 30608:LOC105879208
uniprot id: A0A8B7HCY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WASH1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Recycling endosome membrane

30608:TAF4
gene id: 30608:TAF4
uniprot id: A0A8B7WQ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

30608:UBE2B
gene id: 30608:UBE2B
uniprot id: A0A8B7G6L9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:MBOAT4
gene id: 30608:MBOAT4
uniprot id: A0A8B7HP98
uniprot id: A0A8B7HQX4
uniprot id: A0A8B7HRN6
uniprot id: A0A8C5YE07
names: Subcellular Location Annotation
messages: Membrane

30608:TTC38
gene id: 30608:TTC38
uniprot id: A0A8B7FUN0
uniprot id: A0A8B7X8C1
names: Similarity
messages: Belongs to the TTC38 family.

30608:VCP
gene id: 30608:VCP
uniprot id: A0A8C5UXW8
names: Similarity
messages: Belongs to the AAA ATPase family.

30608:CES5A
gene id: 30608:CES5A
uniprot id: A0A8B7FQX9
uniprot id: A0A8B7FQY3
uniprot id: A0A8B7FR23
uniprot id: A0A8B7FRH4
uniprot id: A0A8B7WSY2
uniprot id: A0A8B7WSY4
uniprot id: A0A8B7WT88
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

30608:ADAM17
gene id: 30608:ADAM17
uniprot id: A0A8B7HT14
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105870333
gene id: 30608:LOC105870333
uniprot id: A0A8B7G8U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

30608:IFNE
gene id: 30608:IFNE
uniprot id: A0A8B7GRH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

30608:LOC105885897
gene id: 30608:LOC105885897
uniprot id: A0A8B7I6R6
names: Similarity
messages: Belongs to the cornifin (SPRR) family.

30608:KCNJ16
gene id: 30608:KCNJ16
uniprot id: A0A8B7F5A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

30608:TVP23C
gene id: 30608:TVP23C
uniprot id: A0A8B7WNA2
uniprot id: A0A8C5V7F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

30608:LOC105863345
gene id: 30608:LOC105863345
uniprot id: A0A8B7FC63
names: Subcellular Location Annotation
messages: nucleoplasm

30608:PDLIM1
gene id: 30608:PDLIM1
uniprot id: A0A8B7GGQ5
names: Subcellular Location Annotation
messages: Z line

30608:PSCA
gene id: 30608:PSCA
uniprot id: A0A8B7HKM8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:GYS2
gene id: 30608:GYS2
uniprot id: A0A8B7HSJ2
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

30608:DKK1
gene id: 30608:DKK1
uniprot id: A0A8C5V0V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

30608:CHN2
gene id: 30608:CHN2
uniprot id: A0A8B7EB07
uniprot id: A0A8B7EDE3
uniprot id: A0A8C5V179
names: Function
messages: GTPase-activating protein for p21-rac.

30608:RPL36AL
gene id: 30608:RPL36AL
uniprot id: A0A8B7FWL8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

30608:DAXX
gene id: 30608:DAXX
uniprot id: A0A8C5VWK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAXX family.
messages: Cytoplasm
messages: PML body
messages: centromere
messages: nucleolus
messages: nucleoplasm

30608:MYO1B
gene id: 30608:MYO1B
uniprot id: A0A8B7H780
uniprot id: A0A8B7H781
uniprot id: A0A8B7H7A1
uniprot id: A0A8B7H9R2
uniprot id: A0A8B7H9R8
uniprot id: A0A8C5W5U4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

30608:GALNT7
gene id: 30608:GALNT7
uniprot id: A0A8B7GTU1
uniprot id: A0A8C5V8J7
uniprot id: A0A8C5VYH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

30608:LIN9
gene id: 30608:LIN9
uniprot id: A0A8C5W532
names: Similarity
messages: Belongs to the lin-9 family.

30608:LOC105882826
gene id: 30608:LOC105882826
uniprot id: A0A8B7HSN0
names: Similarity
messages: Belongs to the SKP1 family.

30608:ABLIM2
gene id: 30608:ABLIM2
uniprot id: A0A8B7HMM0
uniprot id: A0A8B7HMM7
uniprot id: A0A8B7HMN0
uniprot id: A0A8B7HMN1
uniprot id: A0A8B7HMN2
uniprot id: A0A8B7HMN4
uniprot id: A0A8B7HMN7
uniprot id: A0A8B7HMP0
uniprot id: A0A8B7HMP3
uniprot id: A0A8B7HMP4
uniprot id: A0A8B7HMP5
uniprot id: A0A8B7HP53
uniprot id: A0A8B7HP60
uniprot id: A0A8B7HP65
uniprot id: A0A8B7HQ34
uniprot id: A0A8B7HQ45
uniprot id: A0A8B7HQ53
names: Subcellular Location Annotation
messages: Cytoplasm

30608:WDR4
gene id: 30608:WDR4
uniprot id: A0A8B7HCI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat TRM82 family.
messages: Nucleus
messages: Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

30608:INPP4A
gene id: 30608:INPP4A
uniprot id: A0A8B7HWB4
uniprot id: A0A8B7HWB8
uniprot id: A0A8B7HWB9
uniprot id: A0A8B7HWC2
uniprot id: A0A8B7HWC4
uniprot id: A0A8B7HWC6
uniprot id: A0A8B7HWC9
uniprot id: A0A8B7HWD0
uniprot id: A0A8B7HWD1
uniprot id: A0A8B7HWD5
uniprot id: A0A8B7HWD9
uniprot id: A0A8B7HWE3
uniprot id: A0A8B7HYF6
uniprot id: A0A8B7HYG5
uniprot id: A0A8B7HYS0
uniprot id: A0A8B7HYS6
uniprot id: A0A8C5W4H1
uniprot id: A0A8C5WAH5
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

30608:TMEM182
gene id: 30608:TMEM182
uniprot id: A0A8B7ENP5
uniprot id: A0A8B7X2E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

30608:ANK2
gene id: 30608:ANK2
uniprot id: A0A8B7HE17
uniprot id: A0A8B7HE19
uniprot id: A0A8B7HE24
uniprot id: A0A8B7HE25
uniprot id: A0A8B7HE29
uniprot id: A0A8B7HE30
uniprot id: A0A8B7HE33
uniprot id: A0A8B7HE34
uniprot id: A0A8B7HE35
uniprot id: A0A8B7HE38
uniprot id: A0A8B7HE39
uniprot id: A0A8B7HE41
uniprot id: A0A8B7HE45
uniprot id: A0A8B7HE52
uniprot id: A0A8B7HE60
uniprot id: A0A8B7HED8
uniprot id: A0A8B7HEE6
uniprot id: A0A8B7HEF2
uniprot id: A0A8B7HEG0
uniprot id: A0A8B7HGN8
uniprot id: A0A8B7HGQ0
uniprot id: A0A8B7HGQ5
uniprot id: A0A8B7HGR3
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

30608:MRPL14
gene id: 30608:MRPL14
uniprot id: A0A8B7EWD5
uniprot id: A0A8C5XE04
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

30608:TM4SF19
gene id: 30608:TM4SF19
uniprot id: A0A8B7HI58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

30608:LOC109731149
gene id: 30608:LOC109731149
uniprot id: A0A8B7XAJ3
names: Similarity
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.

30608:ANO6
gene id: 30608:ANO6
uniprot id: A0A8B7F7L5
uniprot id: A0A8B7F7S6
uniprot id: A0A8B7F824
uniprot id: A0A8B7F871
uniprot id: A0A8B7F880
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:HN1
gene id: 30608:HN1
uniprot id: A0A8B7HBN9
uniprot id: A0A8B7HBP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

30608:FAM129A
gene id: 30608:FAM129A
uniprot id: A0A8C5V767
names: Similarity
messages: Belongs to the Niban family.

30608:ADCY2
gene id: 30608:ADCY2
uniprot id: A0A8B7EWI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

30608:CDT1
gene id: 30608:CDT1
uniprot id: A0A8B7WSR1
names: Similarity
messages: Belongs to the Cdt1 family.

30608:DCTN1
gene id: 30608:DCTN1
uniprot id: A0A8B7I0G3
uniprot id: A0A8B7I0G8
uniprot id: A0A8B7I0H3
uniprot id: A0A8B7I0H8
uniprot id: A0A8B7I0I6
uniprot id: A0A8B7I2L1
uniprot id: A0A8B7I2L6
uniprot id: A0A8B7I397
uniprot id: A0A8B7I3A2
uniprot id: A0A8B7X265
uniprot id: A0A8B7X269
uniprot id: A0A8B7X2Q6
uniprot id: A0A8B7X3H9
uniprot id: A0A8B7X3X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin 150 kDa subunit family.
messages: Cytoplasm
messages: cell cortex
messages: cytoskeleton

30608:SERPINA7
gene id: 30608:SERPINA7
uniprot id: A0A8B7HZ22
uniprot id: A0A8B7HZH0
names: Similarity
messages: Belongs to the serpin family.

30608:LOC105867990
gene id: 30608:LOC105867990
uniprot id: A0A8C5XD22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

30608:MGAT4D
gene id: 30608:MGAT4D
uniprot id: A0A8C5Y4I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 54 family.
messages: Golgi apparatus membrane

30608:ALDH5A1
gene id: 30608:ALDH5A1
uniprot id: A0A8C5XIF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
messages: Homotetramer.
messages: Mitochondrion

30608:MEOX2
gene id: 30608:MEOX2
uniprot id: A0A8B7EQT7
names: Subcellular Location Annotation
messages: Nucleus

30608:WDR46
gene id: 30608:WDR46
uniprot id: A0A8B7I797
names: Subcellular Location Annotation
messages: nucleolus

30608:LOC105857120
gene id: 30608:LOC105857120
uniprot id: A0A8B7WT23
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:SEPT11
gene id: 30608:SEPT11
uniprot id: A0A8B7EVL4
uniprot id: A0A8B7EVM3
uniprot id: A0A8B7EVN2
uniprot id: A0A8B7EVN8
uniprot id: A0A8B7EVQ5
uniprot id: A0A8C5Y7U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

30608:PTGER2
gene id: 30608:PTGER2
uniprot id: A0A8B7FW10
uniprot id: A0A8B7FWU1
uniprot id: A0A8B7X148
uniprot id: A0A8B7X1M4
uniprot id: A0A8B7X2A4
uniprot id: A0A8C5W8V8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:DDX23
gene id: 30608:DDX23
uniprot id: A0A8B7FX90
names: Similarity
messages: Belongs to the DEAD box helicase family.

30608:LOC105873091
gene id: 30608:LOC105873091
uniprot id: A0A8B7GJK3
names: Similarity
messages: Belongs to the LCE family.

30608:GNA12
gene id: 30608:GNA12
uniprot id: A0A8B7FYU8
uniprot id: A0A8B7FZR0
uniprot id: A0A8B7FZY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

30608:LOC105869715
gene id: 30608:LOC105869715
uniprot id: A0A8B7G4X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CRYAB
gene id: 30608:CRYAB
uniprot id: A0A8B7FAC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
messages: Nucleus

30608:LOC105860863
gene id: 30608:LOC105860863
uniprot id: A0A8B7F324
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZC3H14 family.
messages: Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides.
messages: Nucleus speckle

30608:DNM2
gene id: 30608:DNM2
uniprot id: A0A8B7I598
uniprot id: A0A8B7I5A3
uniprot id: A0A8B7I5A5
uniprot id: A0A8B7I5A8
uniprot id: A0A8B7I5C8
uniprot id: A0A8B7I5D3
uniprot id: A0A8B7I5D8
uniprot id: A0A8B7I7A7
uniprot id: A0A8B7I8G0
uniprot id: A0A8B7I8G5
uniprot id: A0A8B7WWR9
uniprot id: A0A8C5VMV6
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

30608:TPO
gene id: 30608:TPO
uniprot id: A0A8B7G871
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prostaglandin G/H synthase family.
messages: Interacts with DUOX1, DUOX2 and CYBA.
messages: Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:TMEM50B
gene id: 30608:TMEM50B
uniprot id: A0A8B7F4D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

30608:GTF2A2
gene id: 30608:GTF2A2
uniprot id: A0A8C5VF92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.

30608:SYN2
gene id: 30608:SYN2
uniprot id: A0A8B7HU18
names: Similarity
messages: Belongs to the synapsin family.

30608:FGFR1OP2
gene id: 30608:FGFR1OP2
uniprot id: A0A8B7EJX4
uniprot id: A0A8B7EK85
uniprot id: A0A8C5XMD9
names: Similarity
messages: Belongs to the SIKE family.

30608:LOC105877613
gene id: 30608:LOC105877613
uniprot id: A0A8B7X258
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105861318
gene id: 30608:LOC105861318
uniprot id: A0A8B7F2N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PFDN4
gene id: 30608:PFDN4
uniprot id: A0A8B7G3E7
uniprot id: A0A8B7G4T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

30608:PTTG1
gene id: 30608:PTTG1
uniprot id: A0A8B7HUN9
uniprot id: A0A8C5US66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the securin family.
messages: Cytoplasm
messages: Nucleus

30608:FYN
gene id: 30608:FYN
uniprot id: A0A8B7FJ05
uniprot id: A0A8C5VGD5
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

30608:WDPCP
gene id: 30608:WDPCP
uniprot id: A0A8B7GCL9
uniprot id: A0A8B7GCM0
uniprot id: A0A8B7GD57
uniprot id: A0A8B7GD95
uniprot id: A0A8B7GDK6
uniprot id: A0A8B7X240
uniprot id: A0A8C5W9X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat fritz family.
messages: Cell membrane
messages: Membrane
messages: cilium axoneme

30608:FAM174A
gene id: 30608:FAM174A
uniprot id: A0A8C5V1B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

30608:THYN1
gene id: 30608:THYN1
uniprot id: A0A8B7EK36
uniprot id: A0A8B7EMG0
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

30608:LOC105858719
gene id: 30608:LOC105858719
uniprot id: A0A8B7EQZ0
uniprot id: A0A8B7ER13
names: Subcellular Location Annotation
messages: Nucleus

30608:USE1
gene id: 30608:USE1
uniprot id: A0A8B7FPY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:TACC1
gene id: 30608:TACC1
uniprot id: A0A8B7G7X1
uniprot id: A0A8B7G7X5
uniprot id: A0A8B7G7X6
uniprot id: A0A8B7G835
uniprot id: A0A8B7G840
uniprot id: A0A8B7G8L0
uniprot id: A0A8B7G8L5
uniprot id: A0A8B7G908
uniprot id: A0A8B7G913
uniprot id: A0A8B7G918
uniprot id: A0A8B7WSZ2
uniprot id: A0A8C5YC34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: centrosome

30608:F2R
gene id: 30608:F2R
uniprot id: A0A8B7EHC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:GNB5
gene id: 30608:GNB5
uniprot id: A0A8B7G8Z6
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

30608:SLCO1C1
gene id: 30608:SLCO1C1
uniprot id: A0A8B7HSK4
uniprot id: A0A8B7HUU5
uniprot id: A0A8B7X7Q5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:BNIP3L
gene id: 30608:BNIP3L
uniprot id: A0A8B7H3L2
uniprot id: A0A8B7H5N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

30608:GNG10
gene id: 30608:GNG10
uniprot id: A0A8C5XUG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

30608:ATP6V1B2
gene id: 30608:ATP6V1B2
uniprot id: A0A8B7HRL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

30608:OGDH
gene id: 30608:OGDH
uniprot id: A0A8B7G8S1
uniprot id: A0A8B7G909
uniprot id: A0A8B7XDL3
uniprot id: A0A8C5XRF1
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

30608:C2H1orf158
gene id: 30608:C2H1orf158
uniprot id: A0A8B7HS76
uniprot id: A0A8C5YCT4
names: Function
names: Subcellular Location Annotation
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
messages: cilium axoneme

30608:BTK
gene id: 30608:BTK
uniprot id: A0A8B7X009
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cytoplasm

30608:SYBU
gene id: 30608:SYBU
uniprot id: A0A8B7HUK2
uniprot id: A0A8B7HUL2
uniprot id: A0A8B7HWP6
uniprot id: A0A8B7HWS6
uniprot id: A0A8B7X9Z0
uniprot id: A0A8C5V462
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105870540
gene id: 30608:LOC105870540
uniprot id: A0A8B7G8B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SDHAF3
gene id: 30608:SDHAF3
uniprot id: A0A8B7FTW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

30608:FAM109A
gene id: 30608:FAM109A
uniprot id: A0A8B7HAU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Forms homodimers and heterodimers with PHETA. Interacts with OCRL and INPP5B.
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

30608:CCKBR
gene id: 30608:CCKBR
uniprot id: A0A8B7HV89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for gastrin and cholecystokinin. The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

30608:ADGRG1
gene id: 30608:ADGRG1
uniprot id: A0A8B7EVV6
uniprot id: A0A8B7EXV0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: Secreted

30608:CDC20
gene id: 30608:CDC20
uniprot id: A0A8B7H4M7
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

30608:DICER1
gene id: 30608:DICER1
uniprot id: A0A8B7FPV1
uniprot id: A0A8B7FQ57
names: Function
names: Similarity
messages: Belongs to the helicase family. Dicer subfamily.
messages: Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes.

30608:CNOT11
gene id: 30608:CNOT11
uniprot id: A0A8C5UM48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT11 family.
messages: Cytoplasm
messages: Nucleus

30608:PTGDR2
gene id: 30608:PTGDR2
uniprot id: A0A8B7HAR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

30608:GALR2
gene id: 30608:GALR2
uniprot id: A0A8B7HEK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

30608:CD28
gene id: 30608:CD28
uniprot id: A0A8B7EJB9
names: Subcellular Location Annotation
messages: Membrane

30608:MAP2K3
gene id: 30608:MAP2K3
uniprot id: A0A8C5VIY8
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:SERPINC1
gene id: 30608:SERPINC1
uniprot id: A0A8B7GDZ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the serpin family.
messages: Forms protease inhibiting heterodimer with TMPRSS7.
messages: extracellular space

30608:SRRD
gene id: 30608:SRRD
uniprot id: A0A8B7GAC5
names: Similarity
messages: Belongs to the SRR1 family.

30608:AGAP2
gene id: 30608:AGAP2
uniprot id: A0A8B7H7R7
uniprot id: A0A8C5VYK2
uniprot id: A0A8C6EFV9
names: Similarity
messages: Belongs to the centaurin gamma-like family.

30608:SLC12A6
gene id: 30608:SLC12A6
uniprot id: A0A8B7ET33
uniprot id: A0A8B7X1E4
uniprot id: A0A8B7X1G6
uniprot id: A0A8B7X1Y4
uniprot id: A0A8B7X362
uniprot id: A0A8C5V9J5
uniprot id: A0A8C5XQS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

30608:KCNJ2
gene id: 30608:KCNJ2
uniprot id: A0A8C5UUA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ2 subfamily.
messages: Membrane

30608:LOC105874783
gene id: 30608:LOC105874783
uniprot id: A0A8B7GUE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

30608:BEST1
gene id: 30608:BEST1
uniprot id: A0A8C5XUE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.
messages: Cell membrane
messages: Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
messages: Membrane

30608:NSUN4
gene id: 30608:NSUN4
uniprot id: A0A8B7H543
uniprot id: A0A8B7XBQ0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

30608:KANSL2
gene id: 30608:KANSL2
uniprot id: A0A8B7FUP3
uniprot id: A0A8C5XC08
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
messages: Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1.
messages: Nucleus

30608:RIOX2
gene id: 30608:RIOX2
uniprot id: A0A8B7GIU5
uniprot id: A0A8B7GIV2
uniprot id: A0A8C5YIY9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family. MINA53 subfamily.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Nucleus
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.

30608:FZD1
gene id: 30608:FZD1
uniprot id: A0A8B7HDN9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:POMGNT1
gene id: 30608:POMGNT1
uniprot id: A0A8B7X8N5
names: Subcellular Location Annotation
messages: Golgi apparatus membrane

30608:RBL1
gene id: 30608:RBL1
uniprot id: A0A8B7FNA8
uniprot id: A0A8B7FNJ9
uniprot id: A0A8B7FNQ2
uniprot id: A0A8B7FPL3
uniprot id: A0A8C5XC62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

30608:IRF8
gene id: 30608:IRF8
uniprot id: A0A8B7WSV2
names: Subcellular Location Annotation
messages: Nucleus

30608:KCTD20
gene id: 30608:KCTD20
uniprot id: A0A8B7F337
uniprot id: A0A8B7F409
uniprot id: A0A8B7F490
names: Subcellular Location Annotation
messages: Cytoplasm

30608:AP1S3
gene id: 30608:AP1S3
uniprot id: A0A8B7G336
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: Membrane
messages: clathrin-coated pit

30608:TMSB15B
gene id: 30608:TMSB15B
uniprot id: A0A8B7HWX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

30608:KAT5
gene id: 30608:KAT5
uniprot id: A0A8B7HA30
uniprot id: A0A8B7HA32
uniprot id: A0A8B7HA36
uniprot id: A0A8B7HA37
uniprot id: A0A8C5UZE3
uniprot id: A0A8C5VUC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

30608:SLC5A8
gene id: 30608:SLC5A8
uniprot id: A0A8C5VUD4
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

30608:MLF2
gene id: 30608:MLF2
uniprot id: A0A8B7G1S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

30608:MFAP5
gene id: 30608:MFAP5
uniprot id: A0A8B7H8U2
uniprot id: A0A8B7HBG6
uniprot id: A0A8C5VC59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: extracellular matrix

30608:SLC5A6
gene id: 30608:SLC5A6
uniprot id: A0A8B7HZI6
uniprot id: A0A8B7X8Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

30608:RPL24
gene id: 30608:RPL24
uniprot id: A0A8C5YJ94
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

30608:ARRDC5
gene id: 30608:ARRDC5
uniprot id: A0A8B7GNJ4
names: Similarity
messages: Belongs to the arrestin family.

30608:MORF4L1
gene id: 30608:MORF4L1
uniprot id: A0A8B7EHW4
uniprot id: A0A8C5XPU8
names: Subcellular Location Annotation
messages: Nucleus

30608:VEZT
gene id: 30608:VEZT
uniprot id: A0A8B7H3B7
uniprot id: A0A8B7H3C1
uniprot id: A0A8B7H5I1
uniprot id: A0A8C5WB96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vezatin family.
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: adherens junction

30608:LOC105878539
gene id: 30608:LOC105878539
uniprot id: A0A8B7HA40
names: Similarity
messages: Belongs to the GOLGA6 family.

30608:LOC105874381
gene id: 30608:LOC105874381
uniprot id: A0A8C5Y9Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:REV1
gene id: 30608:REV1
uniprot id: A0A8B7HWG9
uniprot id: A0A8B7HYK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-Y family.
messages: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
messages: Nucleus

30608:MAN2A2
gene id: 30608:MAN2A2
uniprot id: A0A8B7XB84
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

30608:TTC39A
gene id: 30608:TTC39A
uniprot id: A0A8B7H5H7
uniprot id: A0A8B7H5I0
uniprot id: A0A8B7H5K7
uniprot id: A0A8B7H7V0
names: Similarity
messages: Belongs to the TTC39 family.

30608:ABCB11
gene id: 30608:ABCB11
uniprot id: A0A8B7X8A9
names: Subcellular Location Annotation
messages: Membrane

30608:CITED2
gene id: 30608:CITED2
uniprot id: A0A8B7F6S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

30608:GBA
gene id: 30608:GBA
uniprot id: A0A8B7GK30
uniprot id: A0A8B7GKP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 30 family.
messages: Lysosome membrane

30608:DIO2
gene id: 30608:DIO2
uniprot id: A0A8B7X2H6
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

30608:PPA1
gene id: 30608:PPA1
uniprot id: A0A8B7WLA6
names: Similarity
messages: Belongs to the PPase family.

30608:GIPR
gene id: 30608:GIPR
uniprot id: A0A8B7G414
uniprot id: A0A8C5W3S6
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105874565
gene id: 30608:LOC105874565
uniprot id: A0A8B7GRT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

30608:DHX8
gene id: 30608:DHX8
uniprot id: A0A8B7HVI2
names: Subcellular Location Annotation
messages: Nucleus

30608:ETFRF1
gene id: 30608:ETFRF1
uniprot id: A0A8C5VUV8
names: Similarity
messages: Belongs to the complex I LYR family.

30608:C1S
gene id: 30608:C1S
uniprot id: A0A8C5W221
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105872033
gene id: 30608:LOC105872033
uniprot id: A0A8B7GEU4
uniprot id: A0A8B7GFA7
names: Similarity
messages: Belongs to the intermediate filament family.

30608:RAB3GAP2
gene id: 30608:RAB3GAP2
uniprot id: A0A8B7WXK1
uniprot id: A0A8B7WY06
uniprot id: A0A8B7WYZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab3-GAP regulatory subunit family.
messages: Cytoplasm

30608:NHP2
gene id: 30608:NHP2
uniprot id: A0A8C5Y8Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

30608:PGP
gene id: 30608:PGP
uniprot id: A0A8B7EWY2
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

30608:ASIC4
gene id: 30608:ASIC4
uniprot id: A0A8B7ELJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

30608:LOC105861645
gene id: 30608:LOC105861645
uniprot id: A0A8B7F505
names: Subcellular Location Annotation
messages: Membrane

30608:TMED6
gene id: 30608:TMED6
uniprot id: A0A8B7ERZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:ANAPC13
gene id: 30608:ANAPC13
uniprot id: A0A8B7HYD7
names: Function
names: Similarity
messages: Belongs to the APC13 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

30608:NUCB2
gene id: 30608:NUCB2
uniprot id: A0A8B7HIX1
uniprot id: A0A8C5XQ13
names: Similarity
messages: Belongs to the nucleobindin family.

30608:RAB18
gene id: 30608:RAB18
uniprot id: A0A8C5YE74
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

30608:SCN5A
gene id: 30608:SCN5A
uniprot id: A0A8B7FS20
uniprot id: A0A8B7FS60
uniprot id: A0A8B7FSP5
uniprot id: A0A8B7X012
uniprot id: A0A8B7X156
uniprot id: A0A8C5YGB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

30608:TMC5
gene id: 30608:TMC5
uniprot id: A0A8B7WNP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

30608:LOC105880126
gene id: 30608:LOC105880126
uniprot id: A0A8B7HGZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

30608:VPS52
gene id: 30608:VPS52
uniprot id: A0A8B7IAF7
names: Similarity
messages: Belongs to the VPS52 family.

30608:TMEM132E
gene id: 30608:TMEM132E
uniprot id: A0A8B7I8V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

30608:HTR1D
gene id: 30608:HTR1D
uniprot id: A0A8B7WMP0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homodimer. Heterodimer with HTR1B.
messages: Membrane

30608:LOC105859215
gene id: 30608:LOC105859215
uniprot id: A0A8B7ET18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TDRD3
gene id: 30608:TDRD3
uniprot id: A0A8B7FAT9
uniprot id: A0A8B7FB02
uniprot id: A0A8C5UXB5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. Plays a role in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, acts as an antiviral factor that participates in the assembly of stress granules together with G3BP1.

30608:KCNN1
gene id: 30608:KCNN1
uniprot id: A0A8B7EAX4
uniprot id: A0A8B7WWC3
names: Subcellular Location Annotation
messages: Membrane

30608:ARMT1
gene id: 30608:ARMT1
uniprot id: A0A8B7EN92
uniprot id: A0A8C5XX99
names: Domain
names: Function
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
messages: Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response.
messages: Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.

30608:ERP29
gene id: 30608:ERP29
uniprot id: A0A8B7HDI6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Does not seem to be a disulfide isomerase.
messages: Endoplasmic reticulum lumen
messages: Homodimer.
messages: Melanosome

30608:ZIC1
gene id: 30608:ZIC1
uniprot id: A0A8B7HNL0
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

30608:ZC3H14
gene id: 30608:ZC3H14
uniprot id: A0A8B7X263
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZC3H14 family.
messages: Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides.
messages: Nucleus speckle

30608:LTK
gene id: 30608:LTK
uniprot id: A0A8B7GGL2
uniprot id: A0A8B7GGM7
uniprot id: A0A8B7GH13
uniprot id: A0A8B7GH23
uniprot id: A0A8B7GHC1
uniprot id: A0A8B7GHC6
uniprot id: A0A8C5V8I8
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.

30608:RPL35
gene id: 30608:RPL35
uniprot id: A0A8B7GV98
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

30608:GPC5
gene id: 30608:GPC5
uniprot id: A0A8B7XDF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

30608:RANBP10
gene id: 30608:RANBP10
uniprot id: A0A8B7ES88
uniprot id: A0A8B7EU23
uniprot id: A0A8B7EUB7
names: Similarity
messages: Belongs to the RANBP9/10 family.

30608:LOC105884740
gene id: 30608:LOC105884740
uniprot id: A0A8B7WTP3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

30608:AKT2
gene id: 30608:AKT2
uniprot id: A0A8B7H1T2
uniprot id: A0A8B7H3P2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

30608:ROPN1L
gene id: 30608:ROPN1L
uniprot id: A0A8B7I6L7
uniprot id: A0A8B7I6M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ropporin family.
messages: flagellum

30608:LOC105883376
gene id: 30608:LOC105883376
uniprot id: A0A8B7HX24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PLCD1
gene id: 30608:PLCD1
uniprot id: A0A8B7FS11
uniprot id: A0A8B7FS50
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

30608:LOC105881934
gene id: 30608:LOC105881934
uniprot id: A0A8B7HNS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ABHD1
gene id: 30608:ABHD1
uniprot id: A0A8B7I276
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

30608:CHAF1A
gene id: 30608:CHAF1A
uniprot id: A0A8B7GNM8
uniprot id: A0A8B7GQ24
uniprot id: A0A8C5VEJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CHAF1A family.
messages: Nucleus

30608:SEMA4F
gene id: 30608:SEMA4F
uniprot id: A0A8B7I0F4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:MYO3A
gene id: 30608:MYO3A
uniprot id: A0A8B7H876
uniprot id: A0A8B7H881
uniprot id: A0A8B7WWA6
uniprot id: A0A8B7WWL8
uniprot id: A0A8B7WX19
uniprot id: A0A8B7WY07
uniprot id: A0A8C5Y228
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: In the C-terminal section; belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: cytoskeleton

30608:NLRP2
gene id: 30608:NLRP2
uniprot id: A0A8B7WUK1
uniprot id: A0A8B7WW69
names: Similarity
messages: Belongs to the NLRP family.

30608:LOC105858287
gene id: 30608:LOC105858287
uniprot id: A0A8B7ERC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

30608:MARS2
gene id: 30608:MARS2
uniprot id: A0A8B7H9Y9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

30608:PRUNE1
gene id: 30608:PRUNE1
uniprot id: A0A8B7GJ75
uniprot id: A0A8B7GJ76
uniprot id: A0A8B7GJJ6
uniprot id: A0A8B7GKB2
names: Similarity
messages: Belongs to the PPase class C family. Prune subfamily.

30608:TOR4A
gene id: 30608:TOR4A
uniprot id: A0A8B7HQ17
names: Similarity
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.

30608:IPPK
gene id: 30608:IPPK
uniprot id: A0A8C5XM03
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 2 family.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

30608:MTCH2
gene id: 30608:MTCH2
uniprot id: A0A8B7I3D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:DYNLRB1
gene id: 30608:DYNLRB1
uniprot id: A0A8B7FMT0
uniprot id: A0A8B7WPV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
messages: Belongs to the GAMAD family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer.
messages: cytoskeleton

30608:ADCYAP1R1
gene id: 30608:ADCYAP1R1
uniprot id: A0A8B7EAN2
uniprot id: A0A8B7EB87
uniprot id: A0A8B7EDA9
names: Subcellular Location Annotation
messages: Membrane

30608:APEX2
gene id: 30608:APEX2
uniprot id: A0A8B7F7M5
uniprot id: A0A8B7F7M9
uniprot id: A0A8B7F7W5
uniprot id: A0A8B7WZ85
uniprot id: A0A8B7X099
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Cytoplasm
messages: Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
messages: Mitochondrion
messages: Nucleus
messages: Probably binds two magnesium or manganese ions per subunit.

30608:GNB2
gene id: 30608:GNB2
uniprot id: A0A8B7FZY0
uniprot id: A0A8C5W927
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

30608:COPS7A
gene id: 30608:COPS7A
uniprot id: A0A8B7G2N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

30608:LOC105870765
gene id: 30608:LOC105870765
uniprot id: A0A8B7WSJ9
names: Similarity
messages: Belongs to the MHC class I family.

30608:IL19
gene id: 30608:IL19
uniprot id: A0A8C5UVA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

30608:CELF4
gene id: 30608:CELF4
uniprot id: A0A8B7FFU5
uniprot id: A0A8B7FFV0
uniprot id: A0A8B7FFV6
uniprot id: A0A8B7FFX4
uniprot id: A0A8B7FG30
uniprot id: A0A8B7FG35
uniprot id: A0A8B7FH05
uniprot id: A0A8B7WRF1
uniprot id: A0A8B7WRF6
uniprot id: A0A8B7WRG4
uniprot id: A0A8B7WRG8
uniprot id: A0A8B7WRI6
uniprot id: A0A8B7WRJ1
uniprot id: A0A8B7WSX0
uniprot id: A0A8C5USD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

30608:MS4A14
gene id: 30608:MS4A14
uniprot id: A0A8B7FUB8
names: Similarity
messages: Belongs to the MS4A family.

30608:MTMR10
gene id: 30608:MTMR10
uniprot id: A0A8C5V6T2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

30608:DIO1
gene id: 30608:DIO1
uniprot id: A0A8B7H5R0
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

30608:MED1
gene id: 30608:MED1
uniprot id: A0A8B7GF77
uniprot id: A0A8B7GG00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

30608:CDH12
gene id: 30608:CDH12
uniprot id: A0A8B7XCT6
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

30608:RHPN1
gene id: 30608:RHPN1
uniprot id: A0A8B7FIH9
uniprot id: A0A8B7FII0
names: Similarity
messages: Belongs to the RHPN family.

30608:HMGB3
gene id: 30608:HMGB3
uniprot id: A0A8B7EDG8
uniprot id: A0A8C5YHG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

30608:HSPA13
gene id: 30608:HSPA13
uniprot id: A0A8B7HTV5
uniprot id: A0A8C5XJ26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Binds UBQLN2.
messages: Endoplasmic reticulum
messages: Has peptide-independent ATPase activity.
messages: Microsome

30608:DDB2
gene id: 30608:DDB2
uniprot id: A0A8B7I1X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Nucleus

30608:CUL9
gene id: 30608:CUL9
uniprot id: A0A8B7GY63
uniprot id: A0A8B7GY66
uniprot id: A0A8B7GY84
uniprot id: A0A8B7H025
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cullin family.
messages: Cytoplasm

30608:LRRC8D
gene id: 30608:LRRC8D
uniprot id: A0A8B7I612
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

30608:AGO1
gene id: 30608:AGO1
uniprot id: A0A8B7GDF4
uniprot id: A0A8B7GDF5
uniprot id: A0A8B7GDZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family.
messages: P-body

30608:OSM
gene id: 30608:OSM
uniprot id: A0A8C5XFG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LIF/OSM family.
messages: Secreted

30608:KCNJ10
gene id: 30608:KCNJ10
uniprot id: A0A8B7F9W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

30608:METTL8
gene id: 30608:METTL8
uniprot id: A0A8B7HK74
uniprot id: A0A8B7X8Y2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

30608:AOC2
gene id: 30608:AOC2
uniprot id: A0A8B7WM71
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

30608:ART4
gene id: 30608:ART4
uniprot id: A0A8C5URM6
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

30608:RAP2B
gene id: 30608:RAP2B
uniprot id: A0A8C5YIV1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Palmitoylated.
messages: Recycling endosome membrane
messages: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form.

30608:C3H14orf159
gene id: 30608:C3H14orf159
uniprot id: A0A8B7H052
uniprot id: A0A8B7H054
uniprot id: A0A8B7H251
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

30608:LOC105875463
gene id: 30608:LOC105875463
uniprot id: A0A8B7GWR9
names: Subcellular Location Annotation
messages: Nucleus

30608:PEX19
gene id: 30608:PEX19
uniprot id: A0A8B7F9D8
uniprot id: A0A8B7F9U7
uniprot id: A0A8C5VCE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxin-19 family.
messages: Interacts with a broad range of peroxisomal membrane proteins, including PEX3, PEX10, PEX11A, PEX11B, PEX12, PEX13, PEX14 and PEX16, PXMP2/PMP22, PXMP4/PMP24, SLC25A17/PMP34, ABCD1/ALDP, ABCD2/ALDRP, and ABCD3/PMP70. Also interacts with the tumor suppressor CDKN2A/p19ARF.
messages: Membrane
messages: Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.
messages: Peroxisome membrane

30608:LOC105859005
gene id: 30608:LOC105859005
uniprot id: A0A8C5VY55
names: Caution
names: Function
names: Similarity
names: Subunit
messages: As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Tetramer of two alpha and two beta chains; disulfide-linked (By similarity). The hemoglobin/haptoglobin complex is composed of a haptoglobin dimer bound to two hemoglobin alpha-beta dimers (By similarity). Interacts with CD163 (By similarity). Interacts with ERGIC3.

30608:FBN3
gene id: 30608:FBN3
uniprot id: A0A8B7I5V1
uniprot id: A0A8B7WWC8
uniprot id: A0A8B7WWR4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:TEX13C
gene id: 30608:TEX13C
uniprot id: A0A8B7G485
names: Similarity
messages: Belongs to the TEX13 family.

30608:SEMA6C
gene id: 30608:SEMA6C
uniprot id: A0A8B7WWV2
uniprot id: A0A8C5Y6G7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:ARHGAP33
gene id: 30608:ARHGAP33
uniprot id: A0A8B7H2K2
uniprot id: A0A8B7H2K4
uniprot id: A0A8B7H2K6
names: Similarity
messages: Belongs to the PX domain-containing GAP family.

30608:LOC105883397
gene id: 30608:LOC105883397
uniprot id: A0A8B7HUZ6
names: Subcellular Location Annotation
messages: Membrane

30608:ZAR1
gene id: 30608:ZAR1
uniprot id: A0A8B7WZH3
names: Similarity
names: Subunit
messages: Belongs to the ZAR1 family.
messages: Interacts with YBX2.

30608:ATG3
gene id: 30608:ATG3
uniprot id: A0A8B7HXN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG3 family.
messages: Cytoplasm

30608:PANX3
gene id: 30608:PANX3
uniprot id: A0A8C5XSV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

30608:LOC105868733
gene id: 30608:LOC105868733
uniprot id: A0A8B7G137
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CDK16
gene id: 30608:CDK16
uniprot id: A0A8B7FAK8
uniprot id: A0A8B7FAL7
uniprot id: A0A8B7FB78
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:OAZ2
gene id: 30608:OAZ2
uniprot id: A0A8C5UT49
names: Similarity
messages: Belongs to the ODC antizyme family.

30608:ESR1
gene id: 30608:ESR1
uniprot id: A0A8B7X5N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

30608:ETV1
gene id: 30608:ETV1
uniprot id: A0A8B7EQT1
uniprot id: A0A8B7EQV5
uniprot id: A0A8B7ESJ3
uniprot id: A0A8C5W2L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

30608:MALRD1
gene id: 30608:MALRD1
uniprot id: A0A8B7WWI3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:GGT5
gene id: 30608:GGT5
uniprot id: A0A8B7F9L5
uniprot id: A0A8B7FA40
names: Similarity
messages: Belongs to the gamma-glutamyltransferase family.

30608:ABCG5
gene id: 30608:ABCG5
uniprot id: A0A8B7FS34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

30608:TRPM2
gene id: 30608:TRPM2
uniprot id: A0A8B7WXZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM2 sub-subfamily.
messages: Cell membrane
messages: Membrane

30608:ERN2
gene id: 30608:ERN2
uniprot id: A0A8B7HF05
uniprot id: A0A8B7HF13
uniprot id: A0A8B7HF18
uniprot id: A0A8B7HF27
uniprot id: A0A8B7HF34
uniprot id: A0A8B7HHP7
uniprot id: A0A8B7WP81
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:LOC105868333
gene id: 30608:LOC105868333
uniprot id: A0A8B7FYC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

30608:MAP1LC3A
gene id: 30608:MAP1LC3A
uniprot id: A0A8B7FN01
names: Similarity
messages: Belongs to the ATG8 family.

30608:LOC105863164
gene id: 30608:LOC105863164
uniprot id: A0A8B7FB96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SFT2D1
gene id: 30608:SFT2D1
uniprot id: A0A8C5WBB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

30608:STAM
gene id: 30608:STAM
uniprot id: A0A8B7F869
uniprot id: A0A8C5UTF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane
messages: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.

30608:C2H1orf43
gene id: 30608:C2H1orf43
uniprot id: A0A8C5W0S4
names: Function
names: Subcellular Location Annotation
messages: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion

30608:PLCB1
gene id: 30608:PLCB1
uniprot id: A0A8B7WQF6
names: Cofactor
names: Function
messages: Binds 1 Ca(2+) ion per subunit.
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

30608:GSX1
gene id: 30608:GSX1
uniprot id: A0A8C6EFL8
names: Subcellular Location Annotation
messages: Nucleus

30608:CHMP4A
gene id: 30608:CHMP4A
uniprot id: A0A8B7FR87
names: Similarity
messages: Belongs to the SNF7 family.

30608:PUS3
gene id: 30608:PUS3
uniprot id: A0A8B7GWC9
uniprot id: A0A8B7GWD1
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

30608:SKIL
gene id: 30608:SKIL
uniprot id: A0A8B7HCX2
uniprot id: A0A8C5YH02
uniprot id: A0A8C5YIY7
names: Similarity
messages: Belongs to the SKI family.

30608:SIX5
gene id: 30608:SIX5
uniprot id: A0A8C5XZ35
names: Subcellular Location Annotation
messages: Nucleus

30608:FUT7
gene id: 30608:FUT7
uniprot id: A0A8B7HQ56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Membrane

30608:IL18
gene id: 30608:IL18
uniprot id: A0A8B7FAA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Cytoplasm
messages: Pro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
messages: Secreted

30608:PLIN2
gene id: 30608:PLIN2
uniprot id: A0A8B7XCL3
names: Similarity
messages: Belongs to the perilipin family.

30608:PGD
gene id: 30608:PGD
uniprot id: A0A8B7WRA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

30608:FEV
gene id: 30608:FEV
uniprot id: A0A8B7ENJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

30608:DGKB
gene id: 30608:DGKB
uniprot id: A0A8B7EQS1
uniprot id: A0A8B7EQT5
uniprot id: A0A8B7ESH6
uniprot id: A0A8B7ESV3
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

30608:EFNB1
gene id: 30608:EFNB1
uniprot id: A0A8B7EBP3
uniprot id: A0A8B7EC98
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:TFAP2E
gene id: 30608:TFAP2E
uniprot id: A0A8C5Y9F9
names: Similarity
messages: Belongs to the AP-2 family.

30608:JUP
gene id: 30608:JUP
uniprot id: A0A8B7GF94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: adherens junction

30608:LHX6
gene id: 30608:LHX6
uniprot id: A0A8B7GUU6
uniprot id: A0A8B7GUV1
uniprot id: A0A8B7GUX6
uniprot id: A0A8B7GV00
uniprot id: A0A8B7GV07
uniprot id: A0A8B7GWL7
uniprot id: A0A8B7XB94
names: Subcellular Location Annotation
messages: Nucleus

30608:CBL
gene id: 30608:CBL
uniprot id: A0A8B7GZK6
names: Domain
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

30608:VPS72
gene id: 30608:VPS72
uniprot id: A0A8B7GJZ1
uniprot id: A0A8C5UWS6
names: Function
names: Similarity
messages: Belongs to the VPS72/YL1 family.
messages: Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling.

30608:LOC105861258
gene id: 30608:LOC105861258
uniprot id: A0A8B7F2I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:DDX17
gene id: 30608:DDX17
uniprot id: A0A8B7ES23
uniprot id: A0A8B7ESG8
names: Similarity
messages: Belongs to the DEAD box helicase family.

30608:GUCY2F
gene id: 30608:GUCY2F
uniprot id: A0A8B7FEW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane
messages: Photoreceptor outer segment membrane

30608:APLNR
gene id: 30608:APLNR
uniprot id: A0A8C5UUA1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:EN2
gene id: 30608:EN2
uniprot id: A0A8B7HUH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

30608:PGM2
gene id: 30608:PGM2
uniprot id: A0A8C5UZA9
uniprot id: A0A8C5XW95
names: Similarity
messages: Belongs to the phosphohexose mutase family.

30608:SLC9A9
gene id: 30608:SLC9A9
uniprot id: A0A8B7G6C8
uniprot id: A0A8B7G736
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Endosome membrane
messages: Recycling endosome membrane

30608:LOC105872554
gene id: 30608:LOC105872554
uniprot id: A0A8B7GH93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

30608:PBX3
gene id: 30608:PBX3
uniprot id: A0A8B7GV74
uniprot id: A0A8B7GV77
uniprot id: A0A8B7GV79
uniprot id: A0A8B7GV95
uniprot id: A0A8B7GVD0
uniprot id: A0A8B7GWZ8
uniprot id: A0A8C6EHG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

30608:MBOAT2
gene id: 30608:MBOAT2
uniprot id: A0A8B7HT31
uniprot id: A0A8B7HT38
uniprot id: A0A8B7HV55
names: Subcellular Location Annotation
messages: Membrane

30608:UVSSA
gene id: 30608:UVSSA
uniprot id: A0A8B7HMF5
uniprot id: A0A8B7HMF8
uniprot id: A0A8B7HMF9
uniprot id: A0A8B7HMG0
uniprot id: A0A8B7HNW8
uniprot id: A0A8B7HPW7
names: Similarity
messages: Belongs to the UVSSA family.

30608:DPM1
gene id: 30608:DPM1
uniprot id: A0A8B7GG79
uniprot id: A0A8B7GGJ1
uniprot id: A0A8B7GGK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins; catalytic subunit of the dolichol-phosphate mannose (DPM) synthase complex.

30608:DCLRE1C
gene id: 30608:DCLRE1C
uniprot id: A0A8B7EFX5
uniprot id: A0A8B7EFY3
uniprot id: A0A8B7EGE4
uniprot id: A0A8B7EGS4
uniprot id: A0A8B7EGS9
uniprot id: A0A8B7EIF1
uniprot id: A0A8C5YCE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

30608:ZSCAN26
gene id: 30608:ZSCAN26
uniprot id: A0A8B7ET61
names: Subcellular Location Annotation
messages: Nucleus

30608:HMMR
gene id: 30608:HMMR
uniprot id: A0A8B7FIY4
names: Subcellular Location Annotation
messages: spindle

30608:CLPTM1L
gene id: 30608:CLPTM1L
uniprot id: A0A8B7H0J2
uniprot id: A0A8B7H0J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

30608:FLT3
gene id: 30608:FLT3
uniprot id: A0A8B7ERM0
uniprot id: A0A8B7XDZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Membrane

30608:KDELR3
gene id: 30608:KDELR3
uniprot id: A0A8C5XBS7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:PPFIA2
gene id: 30608:PPFIA2
uniprot id: A0A8B7G194
uniprot id: A0A8B7X6Y5
uniprot id: A0A8B7X6Y9
uniprot id: A0A8B7X6Z4
uniprot id: A0A8B7X6Z7
uniprot id: A0A8B7X6Z8
uniprot id: A0A8B7X701
uniprot id: A0A8B7X7N0
uniprot id: A0A8B7X7P0
uniprot id: A0A8B7X8P2
uniprot id: A0A8B7X8P7
uniprot id: A0A8B7X8Q1
uniprot id: A0A8B7X8Y4
uniprot id: A0A8B7X8Z8
uniprot id: A0A8B7X903
uniprot id: A0A8C5VF55
uniprot id: A0A8C5VF95
uniprot id: A0A8C5W009
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

30608:STRADB
gene id: 30608:STRADB
uniprot id: A0A8B7EIJ7
uniprot id: A0A8B7EJN1
uniprot id: A0A8B7EL02
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

30608:UNK
gene id: 30608:UNK
uniprot id: A0A8B7HBV4
uniprot id: A0A8B7HEI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

30608:COQ5
gene id: 30608:COQ5
uniprot id: A0A8B7FSC8
uniprot id: A0A8B7FSE8
uniprot id: A0A8B7FT04
uniprot id: A0A8B7FTC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

30608:ADRB3
gene id: 30608:ADRB3
uniprot id: A0A8B7G7U7
uniprot id: A0A8B7G8X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
messages: Cell membrane
messages: Interacts with ARRDC3.
messages: Membrane

30608:SF3B3
gene id: 30608:SF3B3
uniprot id: A0A8B7GYC4
names: Subcellular Location Annotation
messages: Nucleus

30608:GPRC6A
gene id: 30608:GPRC6A
uniprot id: A0A8B7FKY1
uniprot id: A0A8C5XTM8
uniprot id: A0A8C5YFH1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:ARV1
gene id: 30608:ARV1
uniprot id: A0A8B7EGY5
uniprot id: A0A8C5VC97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane

30608:DNASE2B
gene id: 30608:DNASE2B
uniprot id: A0A8B7F5M7
uniprot id: A0A8B7F5P2
uniprot id: A0A8C5VCJ3
names: Similarity
messages: Belongs to the DNase II family.

30608:HOXA3
gene id: 30608:HOXA3
uniprot id: A0A8B7GYR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

30608:LOC105870541
gene id: 30608:LOC105870541
uniprot id: A0A8B7G8C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TMEM11
gene id: 30608:TMEM11
uniprot id: A0A8B7EFT9
uniprot id: A0A8C6EHT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM11 family.
messages: Membrane
messages: Plays a role in mitochondrial morphogenesis.

30608:LOC105862725
gene id: 30608:LOC105862725
uniprot id: A0A8B7F9Z9
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

30608:USP30
gene id: 30608:USP30
uniprot id: A0A8B7FSG9
uniprot id: A0A8B7FSK4
uniprot id: A0A8B7FT52
uniprot id: A0A8B7FTH3
uniprot id: A0A8B7WTT3
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

30608:SERPINF2
gene id: 30608:SERPINF2
uniprot id: A0A8B7EPF7
uniprot id: A0A8B7EQ63
names: Similarity
messages: Belongs to the serpin family.

30608:POU3F3
gene id: 30608:POU3F3
uniprot id: A0A8C5VGB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

30608:MAP3K13
gene id: 30608:MAP3K13
uniprot id: A0A8B7X3S3
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

30608:LOC105884161
gene id: 30608:LOC105884161
uniprot id: A0A8B7HYL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105868730
gene id: 30608:LOC105868730
uniprot id: A0A8B7G1H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SLC43A1
gene id: 30608:SLC43A1
uniprot id: A0A8B7FB86
uniprot id: A0A8C5UPP6
names: Subcellular Location Annotation
messages: Membrane

30608:PODXL2
gene id: 30608:PODXL2
uniprot id: A0A8B7GDB8
names: Subcellular Location Annotation
messages: Membrane

30608:ATXN1
gene id: 30608:ATXN1
uniprot id: A0A8B7FK14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

30608:RRP12
gene id: 30608:RRP12
uniprot id: A0A8B7GJL9
names: Similarity
messages: Belongs to the RRP12 family.

30608:HS3ST2
gene id: 30608:HS3ST2
uniprot id: A0A8B7HHS2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

30608:LOC105861270
gene id: 30608:LOC105861270
uniprot id: A0A8B7F3T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CHD9
gene id: 30608:CHD9
uniprot id: A0A8B7GX04
uniprot id: A0A8B7WSC6
uniprot id: A0A8B7WSD8
uniprot id: A0A8B7WSE1
uniprot id: A0A8B7WSE5
uniprot id: A0A8B7WSE6
uniprot id: A0A8B7WSF1
uniprot id: A0A8B7WSH3
uniprot id: A0A8B7WSJ1
uniprot id: A0A8B7WTW0
uniprot id: A0A8B7WTW5
uniprot id: A0A8B7WTX0
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

30608:FXN
gene id: 30608:FXN
uniprot id: A0A8B7XAJ1
names: Similarity
messages: Belongs to the frataxin family.

30608:NEUROD4
gene id: 30608:NEUROD4
uniprot id: A0A8B7FMN6
names: Subcellular Location Annotation
messages: Nucleus

30608:BLOC1S2
gene id: 30608:BLOC1S2
uniprot id: A0A8B7GN10
names: Similarity
messages: Belongs to the BLOC1S2 family.

30608:NFE2
gene id: 30608:NFE2
uniprot id: A0A8C5XZS7
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

30608:ATG5
gene id: 30608:ATG5
uniprot id: A0A8B7FJ79
uniprot id: A0A8B7FJE6
uniprot id: A0A8B7FKM7
uniprot id: A0A8C5VT00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with ATG12.
messages: Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.
messages: May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.
messages: Preautophagosomal structure membrane

30608:EGFL7
gene id: 30608:EGFL7
uniprot id: A0A8B7HLX2
uniprot id: A0A8B7XBH8
uniprot id: A0A8B7XBH9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:SLC28A2
gene id: 30608:SLC28A2
uniprot id: A0A8C5XNH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

30608:PSD4
gene id: 30608:PSD4
uniprot id: A0A8B7ESZ9
uniprot id: A0A8B7EUT6
uniprot id: A0A8B7EUU2
uniprot id: A0A8B7EUZ7
names: Subcellular Location Annotation
messages: Membrane
messages: ruffle membrane

30608:TM9SF4
gene id: 30608:TM9SF4
uniprot id: A0A8B7FNM3
uniprot id: A0A8B7FNU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

30608:TADA2A
gene id: 30608:TADA2A
uniprot id: A0A8B7WNL3
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105876737
gene id: 30608:LOC105876737
uniprot id: A0A8B7H1F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF152 family.
messages: Lysosome membrane
messages: Membrane

30608:LOC105869170
gene id: 30608:LOC105869170
uniprot id: A0A8B7X5C6
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

30608:TMEM233
gene id: 30608:TMEM233
uniprot id: A0A8C5XFC7
names: Similarity
messages: Belongs to the CD225/Dispanin family.

30608:SLC39A1
gene id: 30608:SLC39A1
uniprot id: A0A8C5VFR6
names: Subcellular Location Annotation
messages: Membrane

30608:PARVG
gene id: 30608:PARVG
uniprot id: A0A8B7FV01
uniprot id: A0A8B7FVW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: Cell membrane
messages: Membrane

30608:ABT1
gene id: 30608:ABT1
uniprot id: A0A8B7ER38
uniprot id: A0A8C5Y3I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: nucleolus

30608:RPS17
gene id: 30608:RPS17
uniprot id: A0A8C5VQ92
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

30608:MRTO4
gene id: 30608:MRTO4
uniprot id: A0A8B7HY63
uniprot id: A0A8C5XBN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

30608:TP63
gene id: 30608:TP63
uniprot id: A0A8B7EYW8
uniprot id: A0A8B7EYX1
uniprot id: A0A8B7EYX2
uniprot id: A0A8B7EYX3
uniprot id: A0A8B7F0N8
uniprot id: A0A8B7F0P3
uniprot id: A0A8B7F122
uniprot id: A0A8B7X543
uniprot id: A0A8C5YI40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Binds DNA as a homotetramer. Isoform composition of the tetramer may determine transactivation activity.
messages: Cytoplasm
messages: Nucleus

30608:KCTD10
gene id: 30608:KCTD10
uniprot id: A0A8B7FSE4
uniprot id: A0A8B7FSF4
uniprot id: A0A8B7FSZ4
uniprot id: A0A8B7FTC4
uniprot id: A0A8B7WTK2
names: Similarity
messages: Belongs to the BACURD family.

30608:SMS
gene id: 30608:SMS
uniprot id: A0A8B7HST5
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

30608:ZNF280C
gene id: 30608:ZNF280C
uniprot id: A0A8B7FCE9
uniprot id: A0A8B7FCF8
uniprot id: A0A8B7FCF9
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor.
messages: Nucleus

30608:LBX2
gene id: 30608:LBX2
uniprot id: A0A8B7I0H7
names: Subcellular Location Annotation
messages: Nucleus

30608:PNLIP
gene id: 30608:PNLIP
uniprot id: A0A8B7H2T0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:SUSD6
gene id: 30608:SUSD6
uniprot id: A0A8B7HHF6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:HPD
gene id: 30608:HPD
uniprot id: A0A8B7HMG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

30608:VPS4A
gene id: 30608:VPS4A
uniprot id: A0A8B7ETQ7
uniprot id: A0A8C5VZX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

30608:PCMTD2
gene id: 30608:PCMTD2
uniprot id: A0A8B7GY03
uniprot id: A0A8B7GY07
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

30608:SPOCK2
gene id: 30608:SPOCK2
uniprot id: A0A8B7G6S9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:ACO2
gene id: 30608:ACO2
uniprot id: A0A8B7X8A6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Mitochondrion

30608:VPS53
gene id: 30608:VPS53
uniprot id: A0A8C5VLY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

30608:SLC17A1
gene id: 30608:SLC17A1
uniprot id: A0A8B7EPA5
uniprot id: A0A8C5UST6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sodium/anion cotransporter family.
messages: Membrane

30608:EBPL
gene id: 30608:EBPL
uniprot id: A0A8B7EET3
uniprot id: A0A8B7XG26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:TMEM214
gene id: 30608:TMEM214
uniprot id: A0A8B7I1I0
uniprot id: A0A8C6EKT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TMEM214 family.
messages: Constitutively interacts with CASP4; required for the localization of procaspase 4 to the ER.
messages: Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:ATP13A4
gene id: 30608:ATP13A4
uniprot id: A0A8B7HF67
uniprot id: A0A8B7HF71
uniprot id: A0A8B7HF94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

30608:HK1
gene id: 30608:HK1
uniprot id: A0A8B7G724
uniprot id: A0A8C5V301
names: Similarity
messages: Belongs to the hexokinase family.

30608:C6H6orf120
gene id: 30608:C6H6orf120
uniprot id: A0A8B7HKG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0669 family.
messages: May be involved in induction of apoptosis in CD4(+) T-cells, but not CD8(+) T-cells or hepatocytes.
messages: Secreted

30608:GABRQ
gene id: 30608:GABRQ
uniprot id: A0A8C5Y603
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:L3MBTL4
gene id: 30608:L3MBTL4
uniprot id: A0A8B7F168
uniprot id: A0A8B7F175
uniprot id: A0A8B7F176
uniprot id: A0A8B7F179
uniprot id: A0A8B7F180
uniprot id: A0A8B7F3J0
uniprot id: A0A8B7F3J2
uniprot id: A0A8B7WRJ7
uniprot id: A0A8B7WRM5
uniprot id: A0A8C5VEE6
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105873486
gene id: 30608:LOC105873486
uniprot id: A0A8B7GLJ0
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

30608:EGFL8
gene id: 30608:EGFL8
uniprot id: A0A8B7ENN0
uniprot id: A0A8B7ENT9
uniprot id: A0A8B7EQ83
uniprot id: A0A8B7EQU3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:PPP1R14A
gene id: 30608:PPP1R14A
uniprot id: A0A8B7H446
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Cytoplasm
messages: Inhibitor of PPP1CA.

30608:LOC105860331
gene id: 30608:LOC105860331
uniprot id: A0A8B7EYG2
uniprot id: A0A8B7F067
uniprot id: A0A8B7F071
uniprot id: A0A8B7F0I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

30608:GABRA6
gene id: 30608:GABRA6
uniprot id: A0A8C5VQR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:LOC105883497
gene id: 30608:LOC105883497
uniprot id: A0A8B7HXL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SEMA3B
gene id: 30608:SEMA3B
uniprot id: A0A8B7WKY1
uniprot id: A0A8B7WL20
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:GNAT2
gene id: 30608:GNAT2
uniprot id: A0A8B7FFC1
names: Similarity
messages: Belongs to the G-alpha family. G(i/o/t/z) subfamily.

30608:IMP4
gene id: 30608:IMP4
uniprot id: A0A8B7G3W1
uniprot id: A0A8C5UY81
names: Subcellular Location Annotation
messages: nucleolus

30608:UGT8
gene id: 30608:UGT8
uniprot id: A0A8B7HE56
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

30608:LOC105858710
gene id: 30608:LOC105858710
uniprot id: A0A8B7ER04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SNU13
gene id: 30608:SNU13
uniprot id: A0A8C5VN66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

30608:SLC4A9
gene id: 30608:SLC4A9
uniprot id: A0A8B7F8P7
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

30608:RBP4
gene id: 30608:RBP4
uniprot id: A0A8C5XQ12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Interacts with TTR.
messages: Retinol-binding protein that mediates retinol transport in blood plasma.
messages: Secreted

30608:DAPK3
gene id: 30608:DAPK3
uniprot id: A0A8B7GQ59
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:DEGS1
gene id: 30608:DEGS1
uniprot id: A0A8B7FER8
uniprot id: A0A8B7WNP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:CCZ1
gene id: 30608:CCZ1
uniprot id: A0A8C5V2G1
names: Similarity
messages: Belongs to the CCZ1 family.

30608:LOC105884115
gene id: 30608:LOC105884115
uniprot id: A0A8B7HYG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:FANCC
gene id: 30608:FANCC
uniprot id: A0A8B7F726
uniprot id: A0A8B7F7A0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. This complex may also include HSP70.
messages: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
messages: Nucleus

30608:CD164
gene id: 30608:CD164
uniprot id: A0A8B7FIX5
uniprot id: A0A8B7FIY2
uniprot id: A0A8B7FJ56
uniprot id: A0A8B7FKC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

30608:SNX1
gene id: 30608:SNX1
uniprot id: A0A8B7FXH2
uniprot id: A0A8B7FYG5
uniprot id: A0A8B7X284
uniprot id: A0A8B7X2X6
uniprot id: A0A8C5VP70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium
messages: trans-Golgi network membrane

30608:HHATL
gene id: 30608:HHATL
uniprot id: A0A8B7GRI8
uniprot id: A0A8B7GST1
names: Subcellular Location Annotation
messages: Membrane

30608:ELP5
gene id: 30608:ELP5
uniprot id: A0A8C5VTX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP5 family.
messages: Cytoplasm
messages: Nucleus

30608:PTGES
gene id: 30608:PTGES
uniprot id: A0A8B7GVY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

30608:CA8
gene id: 30608:CA8
uniprot id: A0A8B7G0T0
uniprot id: A0A8C6EH66
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

30608:FUS
gene id: 30608:FUS
uniprot id: A0A8B7GAM2
uniprot id: A0A8B7GAM7
uniprot id: A0A8B7GB24
uniprot id: A0A8B7GB87
uniprot id: A0A8B7GBP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

30608:LOC105868729
gene id: 30608:LOC105868729
uniprot id: A0A8B7G084
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:FAP
gene id: 30608:FAP
uniprot id: A0A8C5WAE5
names: Subcellular Location Annotation
messages: Cell membrane
messages: invadopodium membrane
messages: lamellipodium membrane

30608:NPPA
gene id: 30608:NPPA
uniprot id: A0A8B7HUI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the natriuretic peptide family.
messages: Cell projection
messages: Homodimer; disulfide-linked antiparallel dimer.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis and vasodilation. In vivo promotes natriuresis and in vitro, vasodilates renal artery strips.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis and vasodilation. In vivo promotes natriuresis. In vitro, selectively vasodilates intestinal and vascular smooth muscle strips.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis and vasodilation. In vivo promotes natriuresis. In vitro, selectively vasodilates intestinal smooth muscle but not vascular smooth muscle strips.
messages: May have a role in cardio-renal homeostasis through regulation of regulation of natriuresis and vasodilation. In vivo promotes natriuresis. In vitro, vasodilates intestinal smooth muscle but not smooth muscle strips.
messages: Secreted

30608:TMEM38B
gene id: 30608:TMEM38B
uniprot id: A0A8C5USY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

30608:LRP4
gene id: 30608:LRP4
uniprot id: A0A8B7X4P9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:MFGE8
gene id: 30608:MFGE8
uniprot id: A0A8B7XA59
uniprot id: A0A8B7XA60
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:ST13
gene id: 30608:ST13
uniprot id: A0A8C5Y8A8
names: Similarity
messages: Belongs to the FAM10 family.

30608:MEIS1
gene id: 30608:MEIS1
uniprot id: A0A8C5VII1
uniprot id: A0A8C5W4K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

30608:SUMO2
gene id: 30608:SUMO2
uniprot id: A0A8B7HBQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

30608:MAP3K6
gene id: 30608:MAP3K6
uniprot id: A0A8B7FCT4
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

30608:SCML4
gene id: 30608:SCML4
uniprot id: A0A8B7FJA1
uniprot id: A0A8B7FJA5
uniprot id: A0A8B7FJE2
uniprot id: A0A8B7FJI9
uniprot id: A0A8B7FKR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

30608:CYFIP2
gene id: 30608:CYFIP2
uniprot id: A0A8B7HIC4
uniprot id: A0A8B7HKU2
uniprot id: A0A8C5W085
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYFIP family.
messages: synaptosome

30608:PLXNB3
gene id: 30608:PLXNB3
uniprot id: A0A8B7FUT5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:TRPV5
gene id: 30608:TRPV5
uniprot id: A0A8B7GKN1
uniprot id: A0A8B7GKZ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:AKR1A1
gene id: 30608:AKR1A1
uniprot id: A0A8B7H4Z4
uniprot id: A0A8B7H4Z7
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

30608:PRPF31
gene id: 30608:PRPF31
uniprot id: A0A8C5UTS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP31 family.
messages: Cajal body

30608:MTAP
gene id: 30608:MTAP
uniprot id: A0A8B7GQD6
uniprot id: A0A8C5VKH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Nucleus

30608:FDPS
gene id: 30608:FDPS
uniprot id: A0A8B7GKM4
uniprot id: A0A8B7GL60
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

30608:LOC105883331
gene id: 30608:LOC105883331
uniprot id: A0A8B7HWZ9
names: Subcellular Location Annotation
messages: Membrane

30608:RARS
gene id: 30608:RARS
uniprot id: A0A8B7WV73
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

30608:LOC105873892
gene id: 30608:LOC105873892
uniprot id: A0A8B7GNU1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:GBX2
gene id: 30608:GBX2
uniprot id: A0A8B7FMQ8
uniprot id: A0A8B7FNU2
names: Subcellular Location Annotation
messages: Nucleus

30608:TPM4
gene id: 30608:TPM4
uniprot id: A0A8B7FWT8
uniprot id: A0A8B7FXT9
uniprot id: A0A8B7WXQ8
uniprot id: A0A8B7WZ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

30608:RBFOX1
gene id: 30608:RBFOX1
uniprot id: A0A8B7H191
uniprot id: A0A8B7H1E5
uniprot id: A0A8B7H1I9
uniprot id: A0A8B7WPP9
uniprot id: A0A8B7WPQ2
uniprot id: A0A8B7WPQ4
uniprot id: A0A8B7WPQ6
uniprot id: A0A8B7WPQ8
uniprot id: A0A8B7WPR2
uniprot id: A0A8B7WPU5
uniprot id: A0A8B7WR37
uniprot id: A0A8B7WR44
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

30608:USP15
gene id: 30608:USP15
uniprot id: A0A8B7HK30
uniprot id: A0A8B7HK31
uniprot id: A0A8B7HK33
uniprot id: A0A8B7HK36
uniprot id: A0A8B7HLA0
uniprot id: A0A8B7HMM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Nucleus

30608:TNFRSF25
gene id: 30608:TNFRSF25
uniprot id: A0A8B7I7K4
uniprot id: A0A8B7I9L3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:SLC1A4
gene id: 30608:SLC1A4
uniprot id: A0A8B7GDC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

30608:CPNE8
gene id: 30608:CPNE8
uniprot id: A0A8B7X6C3
names: Similarity
messages: Belongs to the copine family.

30608:IKBKB
gene id: 30608:IKBKB
uniprot id: A0A8B7H8B7
uniprot id: A0A8B7WRU6
uniprot id: A0A8B7WRW7
uniprot id: A0A8C5WAZ3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:ATF7IP2
gene id: 30608:ATF7IP2
uniprot id: A0A8B7HRN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCAF family.
messages: Nucleus

30608:GRIK4
gene id: 30608:GRIK4
uniprot id: A0A8B7GZ31
uniprot id: A0A8B7GZ36
uniprot id: A0A8B7GZ69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

30608:LOC109731319
gene id: 30608:LOC109731319
uniprot id: A0A8C5UU26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

30608:VAC14
gene id: 30608:VAC14
uniprot id: A0A8B7WSB6
uniprot id: A0A8B7WSC0
uniprot id: A0A8B7WTU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAC14 family.
messages: Endosome membrane
messages: Microsome membrane

30608:TEKT5
gene id: 30608:TEKT5
uniprot id: A0A8B7HTT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

30608:LOC105873007
gene id: 30608:LOC105873007
uniprot id: A0A8B7WX14
names: Similarity
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

30608:LOC105874763
gene id: 30608:LOC105874763
uniprot id: A0A8B7X0Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

30608:DNAH7
gene id: 30608:DNAH7
uniprot id: A0A8B7H789
uniprot id: A0A8B7H796
uniprot id: A0A8B7H797
names: Similarity
messages: Belongs to the dynein heavy chain family.

30608:FAM114A1
gene id: 30608:FAM114A1
uniprot id: A0A8B7FL78
uniprot id: A0A8B7FLD5
uniprot id: A0A8B7FMK3
uniprot id: A0A8B7FMK7
names: Similarity
messages: Belongs to the FAM114 family.

30608:SLC6A11
gene id: 30608:SLC6A11
uniprot id: A0A8B7HRY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

30608:VIL1
gene id: 30608:VIL1
uniprot id: A0A8C5UQ20
names: Similarity
messages: Belongs to the villin/gelsolin family.

30608:IL2RB
gene id: 30608:IL2RB
uniprot id: A0A8B7HYV9
uniprot id: A0A8B7HZ93
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Cell membrane
messages: Membrane
messages: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. Interacts with SHB upon interleukin stimulation.

30608:HDHD2
gene id: 30608:HDHD2
uniprot id: A0A8B7EZE2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

30608:CDX2
gene id: 30608:CDX2
uniprot id: A0A8B7ERN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

30608:LOC105854773
gene id: 30608:LOC105854773
uniprot id: A0A8B7G6W9
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

30608:LOC105864467
gene id: 30608:LOC105864467
uniprot id: A0A8B7FH66
names: Subcellular Location Annotation
messages: Membrane

30608:XKR6
gene id: 30608:XKR6
uniprot id: A0A8B7WSI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

30608:DMRTC2
gene id: 30608:DMRTC2
uniprot id: A0A8B7WVS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

30608:LIPG
gene id: 30608:LIPG
uniprot id: A0A8C5XNX4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:RYBP
gene id: 30608:RYBP
uniprot id: A0A8B7HXG0
names: Subcellular Location Annotation
messages: Nucleus

30608:IL36RN
gene id: 30608:IL36RN
uniprot id: A0A8B7EST7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

30608:STK32A
gene id: 30608:STK32A
uniprot id: A0A8B7H0N6
uniprot id: A0A8B7H0U9
uniprot id: A0A8B7H2P1
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:SLC10A2
gene id: 30608:SLC10A2
uniprot id: A0A8B7FHN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

30608:NUPR1
gene id: 30608:NUPR1
uniprot id: A0A8C5YBM8
names: Similarity
messages: Belongs to the NUPR family.

30608:CFLAR
gene id: 30608:CFLAR
uniprot id: A0A8B7EIL5
uniprot id: A0A8B7EIL7
uniprot id: A0A8B7EIZ3
names: Similarity
messages: Belongs to the peptidase C14A family.

30608:LOC105862155
gene id: 30608:LOC105862155
uniprot id: A0A8B7F777
uniprot id: A0A8B7F7A4
uniprot id: A0A8B7F7E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).
messages: Belongs to the cytochrome P450 family.
messages: Mitochondrion inner membrane

30608:LOC105870798
gene id: 30608:LOC105870798
uniprot id: A0A8B7GAG2
names: Similarity
messages: Belongs to the UFM1 family.

30608:LOC105881053
gene id: 30608:LOC105881053
uniprot id: A0A8B7WR13
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:TRABD2B
gene id: 30608:TRABD2B
uniprot id: A0A8B7H593
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

30608:LOC105865908
gene id: 30608:LOC105865908
uniprot id: A0A8B7FPQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Odorant receptor.

30608:TSSC4
gene id: 30608:TSSC4
uniprot id: A0A8B7FV49
uniprot id: A0A8B7FVB1
uniprot id: A0A8B7FW44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TSSC4 family.
messages: Cytoplasm
messages: Nucleus

30608:LIN7C
gene id: 30608:LIN7C
uniprot id: A0A8C5Y9D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the lin-7 family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.
messages: Postsynaptic density membrane
messages: tight junction

30608:LOC105865103
gene id: 30608:LOC105865103
uniprot id: A0A8B7X5L2
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

30608:TH
gene id: 30608:TH
uniprot id: A0A8C5VAF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
messages: axon
messages: perinuclear region
messages: synaptic vesicle

30608:KCNA7
gene id: 30608:KCNA7
uniprot id: A0A8C5XGI3
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105871362
gene id: 30608:LOC105871362
uniprot id: A0A8B7GD09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

30608:LEPROTL1
gene id: 30608:LEPROTL1
uniprot id: A0A8B7HPA3
uniprot id: A0A8C6EDG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

30608:YTHDC1
gene id: 30608:YTHDC1
uniprot id: A0A8B7G2X0
uniprot id: A0A8B7G2X1
uniprot id: A0A8B7G2X2
uniprot id: A0A8B7G2X8
uniprot id: A0A8B7G3R4
uniprot id: A0A8B7G4B5
uniprot id: A0A8C5VIB3
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

30608:TM9SF2
gene id: 30608:TM9SF2
uniprot id: A0A8B7FGB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

30608:DIMT1
gene id: 30608:DIMT1
uniprot id: A0A8B7HRG5
uniprot id: A0A8B7XEX9
uniprot id: A0A8C5VZ50
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:ITGAM
gene id: 30608:ITGAM
uniprot id: A0A8B7GB14
uniprot id: A0A8C6EJU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

30608:CLDN17
gene id: 30608:CLDN17
uniprot id: A0A8B7HHH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

30608:MMRN1
gene id: 30608:MMRN1
uniprot id: A0A8C5XL34
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:MAP1LC3C
gene id: 30608:MAP1LC3C
uniprot id: A0A8C6EHJ9
names: Similarity
messages: Belongs to the ATG8 family.

30608:OLAH
gene id: 30608:OLAH
uniprot id: A0A8B7EFZ5
names: Similarity
messages: Belongs to the thioesterase family.

30608:TRIM54
gene id: 30608:TRIM54
uniprot id: A0A8B7HZJ8
uniprot id: A0A8B7HZJ9
names: Function
names: Subcellular Location Annotation
messages: May bind and stabilize microtubules during myotubes formation.
messages: Z line

30608:B3GAT3
gene id: 30608:B3GAT3
uniprot id: A0A8B7HAF7
uniprot id: A0A8B7HAG1
uniprot id: A0A8B7HD68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:IFI44L
gene id: 30608:IFI44L
uniprot id: A0A8C5VQN3
uniprot id: A0A8C6EIH2
names: Similarity
messages: Belongs to the IFI44 family.

30608:OLA1
gene id: 30608:OLA1
uniprot id: A0A8B7FL58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Monomer.
messages: Nucleus
messages: nucleolus

30608:TCTN3
gene id: 30608:TCTN3
uniprot id: A0A8B7GIK1
uniprot id: A0A8C5VKZ1
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

30608:LY6G5C
gene id: 30608:LY6G5C
uniprot id: A0A8C5YGD5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Forms oligomers.
messages: May have a role in hematopoietic cell differentiation.
messages: Secreted

30608:LOC105883765
gene id: 30608:LOC105883765
uniprot id: A0A8B7HWY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-54 family.
messages: Nucleus

30608:SLC24A2
gene id: 30608:SLC24A2
uniprot id: A0A8B7GPW9
uniprot id: A0A8B7GQC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

30608:GPR137C
gene id: 30608:GPR137C
uniprot id: A0A8B7FVQ2
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

30608:RANBP17
gene id: 30608:RANBP17
uniprot id: A0A8B7FTE7
uniprot id: A0A8B7FTF6
uniprot id: A0A8B7FU61
uniprot id: A0A8B7FU66
uniprot id: A0A8B7FUE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

30608:STMN4
gene id: 30608:STMN4
uniprot id: A0A8B7H3H9
uniprot id: A0A8C5V046
uniprot id: A0A8C5VRK0
uniprot id: A0A8C5VWH5
names: Similarity
messages: Belongs to the stathmin family.

30608:SH3BGRL
gene id: 30608:SH3BGRL
uniprot id: A0A8B7I4M3
uniprot id: A0A8B7I6M5
names: Similarity
messages: Belongs to the SH3BGR family.

30608:RAD23A
gene id: 30608:RAD23A
uniprot id: A0A8B7I6V5
uniprot id: A0A8B7I804
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

30608:RGS2
gene id: 30608:RGS2
uniprot id: A0A8C5XPY7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: nucleolus

30608:TMEM199
gene id: 30608:TMEM199
uniprot id: A0A8B7EMP1
uniprot id: A0A8B7EMV3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:LOC105855511
gene id: 30608:LOC105855511
uniprot id: A0A8B7ECR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEG1 family.
messages: Secreted

30608:DOPEY2
gene id: 30608:DOPEY2
uniprot id: A0A8B7WYK8
names: Similarity
messages: Belongs to the dopey family.

30608:TMOD3
gene id: 30608:TMOD3
uniprot id: A0A8C5VH17
names: Subcellular Location Annotation
messages: cytoskeleton

30608:DCLK3
gene id: 30608:DCLK3
uniprot id: A0A8C6ELH6
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

30608:KRT2
gene id: 30608:KRT2
uniprot id: A0A8B7G7Y9
uniprot id: A0A8B7G8N1
names: Similarity
messages: Belongs to the intermediate filament family.

30608:ZDHHC12
gene id: 30608:ZDHHC12
uniprot id: A0A8B7GVT7
uniprot id: A0A8C5V5M5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

30608:HHAT
gene id: 30608:HHAT
uniprot id: A0A8B7HIJ9
uniprot id: A0A8B7HIK1
uniprot id: A0A8B7HIM5
uniprot id: A0A8C5VX13
names: Subcellular Location Annotation
messages: Membrane

30608:ARF5
gene id: 30608:ARF5
uniprot id: A0A8C5UHX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

30608:ATRN
gene id: 30608:ATRN
uniprot id: A0A8B7FNB7
uniprot id: A0A8B7FNJ0
uniprot id: A0A8B7FNK4
uniprot id: A0A8B7FNR2
uniprot id: A0A8B7WQR2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:ADAM7
gene id: 30608:ADAM7
uniprot id: A0A8B7H0Z1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:NR2F6
gene id: 30608:NR2F6
uniprot id: A0A8B7FPZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

30608:PLA2G12A
gene id: 30608:PLA2G12A
uniprot id: A0A8B7WXD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Secreted

30608:PIK3CB
gene id: 30608:PIK3CB
uniprot id: A0A8B7F994
uniprot id: A0A8B7X2E8
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

30608:LOC105868203
gene id: 30608:LOC105868203
uniprot id: A0A8B7FXQ7
uniprot id: A0A8B7FYV0
names: Similarity
messages: Belongs to the TCP11 family.

30608:LOC105881937
gene id: 30608:LOC105881937
uniprot id: A0A8B7X412
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105868237
gene id: 30608:LOC105868237
uniprot id: A0A8B7FXS3
names: Subcellular Location Annotation
messages: Nucleus

30608:SNX11
gene id: 30608:SNX11
uniprot id: A0A8B7GFY2
uniprot id: A0A8C5VXT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

30608:GSDMA
gene id: 30608:GSDMA
uniprot id: A0A8B7GGD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

30608:PPM1B
gene id: 30608:PPM1B
uniprot id: A0A8B7FRU6
uniprot id: A0A8B7FRX1
uniprot id: A0A8B7FSC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

30608:CUL4B
gene id: 30608:CUL4B
uniprot id: A0A8B7EIG3
uniprot id: A0A8B7EIG9
uniprot id: A0A8B7EJH7
uniprot id: A0A8B7EKV3
uniprot id: A0A8B7WZ24
names: Similarity
messages: Belongs to the cullin family.

30608:TMEM87A
gene id: 30608:TMEM87A
uniprot id: A0A8B7GGU1
uniprot id: A0A8B7GH86
uniprot id: A0A8B7GH90
uniprot id: A0A8B7GHI1
uniprot id: A0A8B7GHI6
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105863618
gene id: 30608:LOC105863618
uniprot id: A0A8B7FDR8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

30608:ELF3
gene id: 30608:ELF3
uniprot id: A0A8B7EX04
uniprot id: A0A8C5Y9E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

30608:SLC7A2
gene id: 30608:SLC7A2
uniprot id: A0A8B7HTD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

30608:EPHA4
gene id: 30608:EPHA4
uniprot id: A0A8B7EST5
uniprot id: A0A8C5XQE6
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome
messages: Membrane

30608:NMBR
gene id: 30608:NMBR
uniprot id: A0A8B7EU49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105862437
gene id: 30608:LOC105862437
uniprot id: A0A8B7F899
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:KCNK5
gene id: 30608:KCNK5
uniprot id: A0A8B7F361
uniprot id: A0A8B7F419
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

30608:LOC105874747
gene id: 30608:LOC105874747
uniprot id: A0A8B7GSL5
uniprot id: A0A8B7GSL6
uniprot id: A0A8B7GSV4
uniprot id: A0A8B7GUB9
uniprot id: A0A8B7WYK4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:CDK5RAP1
gene id: 30608:CDK5RAP1
uniprot id: A0A8B7WPU6
names: Similarity
messages: Belongs to the methylthiotransferase family. MiaB subfamily.

30608:LOC105865706
gene id: 30608:LOC105865706
uniprot id: A0A8B7FMN5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105881591
gene id: 30608:LOC105881591
uniprot id: A0A8B7X498
names: Subcellular Location Annotation
messages: Membrane

30608:ELF2
gene id: 30608:ELF2
uniprot id: A0A8B7GG65
uniprot id: A0A8B7GGM6
uniprot id: A0A8B7GGX7
uniprot id: A0A8B7GGY6
uniprot id: A0A8B7GH10
uniprot id: A0A8B7GH16
uniprot id: A0A8C5Y8E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

30608:ENO2
gene id: 30608:ENO2
uniprot id: A0A8B7G2G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

30608:IL36B
gene id: 30608:IL36B
uniprot id: A0A8C5VCW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

30608:NAPRT
gene id: 30608:NAPRT
uniprot id: A0A8B7FII7
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

30608:BLOC1S3
gene id: 30608:BLOC1S3
uniprot id: A0A8B7G409
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BLOC1S3 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO).
messages: Cytoplasm

30608:PTPRU
gene id: 30608:PTPRU
uniprot id: A0A8B7FDB3
uniprot id: A0A8B7FDB8
uniprot id: A0A8B7FDB9
uniprot id: A0A8B7FDD3
uniprot id: A0A8B7FDJ2
uniprot id: A0A8B7FE67
uniprot id: A0A8B7FE71
uniprot id: A0A8C5Y0K6
uniprot id: A0A8C5YBJ5
uniprot id: A0A8C5YEE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

30608:LTA4H
gene id: 30608:LTA4H
uniprot id: A0A8C5VG47
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

30608:SLC11A1
gene id: 30608:SLC11A1
uniprot id: A0A8B7ELP9
uniprot id: A0A8B7ELQ3
uniprot id: A0A8B7ELZ6
uniprot id: A0A8B7EN35
uniprot id: A0A8B7ENZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

30608:LOC105857252
gene id: 30608:LOC105857252
uniprot id: A0A8B7EM60
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:LOC109729614
gene id: 30608:LOC109729614
uniprot id: A0A8B7WQU1
names: Similarity
messages: Belongs to the MHC class I family.

30608:GRK3
gene id: 30608:GRK3
uniprot id: A0A8B7FSI5
uniprot id: A0A8B7FT30
uniprot id: A0A8B7FTF3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

30608:LOC105870379
gene id: 30608:LOC105870379
uniprot id: A0A8B7WU70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative pheromone receptor.

30608:TFE3
gene id: 30608:TFE3
uniprot id: A0A8B7EGB2
uniprot id: A0A8B7EGB9
uniprot id: A0A8C5V048
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

30608:MYF5
gene id: 30608:MYF5
uniprot id: A0A8B7G0V6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
messages: Nucleus

30608:FAM229B
gene id: 30608:FAM229B
uniprot id: A0A8B7X6N5
names: Similarity
messages: Belongs to the FAM229 family.

30608:DGAT2
gene id: 30608:DGAT2
uniprot id: A0A8C5XXD2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:BAIAP2
gene id: 30608:BAIAP2
uniprot id: A0A8B7I2J4
uniprot id: A0A8C5W9K5
uniprot id: A0A8C5XUV1
uniprot id: A0A8C5XY61
names: Function
names: Subcellular Location Annotation
messages: Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
messages: Membrane
messages: cytoskeleton
messages: filopodium
messages: ruffle

30608:PRDM14
gene id: 30608:PRDM14
uniprot id: A0A8B7GU54
names: Subcellular Location Annotation
messages: Nucleus

30608:PGLYRP1
gene id: 30608:PGLYRP1
uniprot id: A0A8C5XR46
names: Function
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
messages: Innate immunity protein that plays several important functions in antimicrobial and antitumor defense systems.

30608:SLX4
gene id: 30608:SLX4
uniprot id: A0A8B7EVK3
uniprot id: A0A8B7WP86
names: Similarity
messages: Belongs to the SLX4 family.

30608:SZRD1
gene id: 30608:SZRD1
uniprot id: A0A8B7G844
uniprot id: A0A8B7G847
uniprot id: A0A8B7G8A7
uniprot id: A0A8B7G986
names: Similarity
messages: Belongs to the SZRD1 family.

30608:DUPD1
gene id: 30608:DUPD1
uniprot id: A0A8B7G0I1
uniprot id: A0A8B7G1E1
uniprot id: A0A8B7G1T1
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

30608:GFRAL
gene id: 30608:GFRAL
uniprot id: A0A8B7HGJ3
names: Similarity
messages: Belongs to the GDNFR family.

30608:LOC105869919
gene id: 30608:LOC105869919
uniprot id: A0A8B7G6W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Cell membrane
messages: Membrane

30608:LOC105863187
gene id: 30608:LOC105863187
uniprot id: A0A8B7FBE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CybS family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

30608:C16H17orf105
gene id: 30608:C16H17orf105
uniprot id: A0A8B7HXQ4
uniprot id: A0A8B7HXU2
names: Similarity
messages: Belongs to the CFAP97 family.

30608:CEL
gene id: 30608:CEL
uniprot id: A0A8B7EW29
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

30608:LOC105873215
gene id: 30608:LOC105873215
uniprot id: A0A8C5W9L7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

30608:COPZ2
gene id: 30608:COPZ2
uniprot id: A0A8B7GG87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

30608:LOC105855581
gene id: 30608:LOC105855581
uniprot id: A0A8B7EF91
names: Similarity
messages: Belongs to the FAM47 family.

30608:KIFC2
gene id: 30608:KIFC2
uniprot id: A0A8B7XB97
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:IL20
gene id: 30608:IL20
uniprot id: A0A8B7G1S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

30608:PELI1
gene id: 30608:PELI1
uniprot id: A0A8B7GD71
uniprot id: A0A8B7GDM1
names: Function
names: Similarity
messages: Belongs to the pellino family.
messages: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

30608:LOC105880740
gene id: 30608:LOC105880740
uniprot id: A0A8B7XDC4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Membrane

30608:LOC105859402
gene id: 30608:LOC105859402
uniprot id: A0A8B7EVW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation.
messages: centrosome

30608:LOC105872876
gene id: 30608:LOC105872876
uniprot id: A0A8B7GIL9
uniprot id: A0A8B7GJ90
uniprot id: A0A8B7GJN0
names: Similarity
messages: Belongs to the DOCK family.

30608:DSCR3
gene id: 30608:DSCR3
uniprot id: A0A8B7HLC1
uniprot id: A0A8B7HLC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS26 family.
messages: Endosome

30608:FGA
gene id: 30608:FGA
uniprot id: A0A8C5UP64
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

30608:UCP2
gene id: 30608:UCP2
uniprot id: A0A8C5W6W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:SNRNP27
gene id: 30608:SNRNP27
uniprot id: A0A8B7FBN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNUT3 family.
messages: May play a role in mRNA splicing.
messages: Nucleus
messages: Part of a tri-snRNP complex.

30608:ADGRF2
gene id: 30608:ADGRF2
uniprot id: A0A8C5VNM0
names: Subcellular Location Annotation
messages: Membrane

30608:ARHGEF7
gene id: 30608:ARHGEF7
uniprot id: A0A8B7FG36
uniprot id: A0A8B7FG41
uniprot id: A0A8B7FG54
uniprot id: A0A8B7FG68
uniprot id: A0A8B7FG74
uniprot id: A0A8B7FGC9
uniprot id: A0A8B7FHA5
uniprot id: A0A8C5VCK0
uniprot id: A0A8C5VQ68
uniprot id: A0A8C5VSI4
names: Subcellular Location Annotation
messages: lamellipodium

30608:LOC105884145
gene id: 30608:LOC105884145
uniprot id: A0A8C5Y9N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:HOXB3
gene id: 30608:HOXB3
uniprot id: A0A8B7GFZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

30608:LOC105855641
gene id: 30608:LOC105855641
uniprot id: A0A8B7ECQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

30608:MUSK
gene id: 30608:MUSK
uniprot id: A0A8B7ECT8
uniprot id: A0A8B7ECT9
uniprot id: A0A8B7ECU2
uniprot id: A0A8B7EDC2
uniprot id: A0A8B7EFG6
uniprot id: A0A8C5VEC7
uniprot id: A0A8C5XH87
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:DACT3
gene id: 30608:DACT3
uniprot id: A0A8B7G4Z6
names: Similarity
messages: Belongs to the dapper family.

30608:USP22
gene id: 30608:USP22
uniprot id: A0A8B7WNG3
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

30608:TRMT5
gene id: 30608:TRMT5
uniprot id: A0A8B7H8X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

30608:C9H8orf82
gene id: 30608:C9H8orf82
uniprot id: A0A8B7G0P5
names: Similarity
messages: Belongs to the UPF0598 family.

30608:ZNF215
gene id: 30608:ZNF215
uniprot id: A0A8B7EYE7
uniprot id: A0A8C5XDC4
names: Subcellular Location Annotation
messages: Nucleus

30608:MDGA2
gene id: 30608:MDGA2
uniprot id: A0A8B7F2A5
uniprot id: A0A8B7F2B1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:LOC105872072
gene id: 30608:LOC105872072
uniprot id: A0A8B7GFR0
names: Similarity
messages: Belongs to the intermediate filament family.

30608:HGF
gene id: 30608:HGF
uniprot id: A0A8B7HDF1
uniprot id: A0A8B7HDM9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Dimer of an alpha chain and a beta chain linked by a disulfide bond. Interacts with SRPX2; the interaction increases HGF mitogenic activity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.

30608:KCNAB3
gene id: 30608:KCNAB3
uniprot id: A0A8B7H4E9
uniprot id: A0A8B7H6N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cytoplasm

30608:LOC105885543
gene id: 30608:LOC105885543
uniprot id: A0A8B7WVP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MMACHC
gene id: 30608:MMACHC
uniprot id: A0A8B7H4Z6
names: Similarity
messages: Belongs to the MMACHC family.

30608:RAMP3
gene id: 30608:RAMP3
uniprot id: A0A8B7GA13
names: Similarity
messages: Belongs to the RAMP family.

30608:LAMTOR3
gene id: 30608:LAMTOR3
uniprot id: A0A8C5VDN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR3 family.
messages: Endosome membrane
messages: Late endosome membrane

30608:FAM13A
gene id: 30608:FAM13A
uniprot id: A0A8B7H0C5
uniprot id: A0A8B7H0C6
uniprot id: A0A8B7H0D0
uniprot id: A0A8B7H0D2
uniprot id: A0A8B7H0D3
uniprot id: A0A8B7H0D5
uniprot id: A0A8B7H0D7
uniprot id: A0A8B7H0J5
uniprot id: A0A8B7H0K4
uniprot id: A0A8B7H2C7
uniprot id: A0A8B7H2D2
uniprot id: A0A8B7H2D7
uniprot id: A0A8C5VJV0
names: Similarity
messages: Belongs to the FAM13 family.

30608:TMEM237
gene id: 30608:TMEM237
uniprot id: A0A8B7EIH8
uniprot id: A0A8B7EII0
uniprot id: A0A8B7EJK6
uniprot id: A0A8B7EKY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM237 family.
messages: Component of the transition zone in primary cilia. Required for ciliogenesis.
messages: Membrane
messages: cilium

30608:LOC105884646
gene id: 30608:LOC105884646
uniprot id: A0A8B7X775
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

30608:ATG16L1
gene id: 30608:ATG16L1
uniprot id: A0A8B7I7N9
uniprot id: A0A8C5XUA1
names: Similarity
messages: Belongs to the WD repeat ATG16 family.

30608:PGC
gene id: 30608:PGC
uniprot id: A0A8B7H0G1
names: Similarity
messages: Belongs to the peptidase A1 family.

30608:LOC105883355
gene id: 30608:LOC105883355
uniprot id: A0A8B7HUV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105865012
gene id: 30608:LOC105865012
uniprot id: A0A8C5W9H7
names: Similarity
messages: Belongs to the SH3BGR family.

30608:RRM1
gene id: 30608:RRM1
uniprot id: A0A8B7EY63
uniprot id: A0A8B7EY64
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

30608:ITGB3BP
gene id: 30608:ITGB3BP
uniprot id: A0A8B7GI78
uniprot id: A0A8B7GI85
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcription coregulator that can have both coactivator and corepressor functions.
messages: centromere
messages: kinetochore

30608:FAM205A
gene id: 30608:FAM205A
uniprot id: A0A8B7GR33
names: Similarity
messages: Belongs to the SPATA31 family.

30608:DUSP6
gene id: 30608:DUSP6
uniprot id: A0A8B7FKY3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

30608:CTNNB1
gene id: 30608:CTNNB1
uniprot id: A0A8B7GSQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: adherens junction

30608:LOC105861436
gene id: 30608:LOC105861436
uniprot id: A0A8B7F498
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

30608:LRRFIP2
gene id: 30608:LRRFIP2
uniprot id: A0A8B7EZF3
uniprot id: A0A8B7EZF6
uniprot id: A0A8B7F1N9
uniprot id: A0A8B7X0B2
uniprot id: A0A8B7X0B3
uniprot id: A0A8B7X0B7
uniprot id: A0A8B7X0C1
uniprot id: A0A8B7X0C3
uniprot id: A0A8B7X0C6
uniprot id: A0A8B7X0C8
uniprot id: A0A8B7X0D4
uniprot id: A0A8B7X0V0
uniprot id: A0A8B7X0V5
uniprot id: A0A8B7X0W4
uniprot id: A0A8B7X0W6
uniprot id: A0A8B7X0W9
uniprot id: A0A8B7X0X2
uniprot id: A0A8B7X1E9
uniprot id: A0A8B7X1F9
uniprot id: A0A8B7X1G5
uniprot id: A0A8B7X1G9
uniprot id: A0A8B7X234
uniprot id: A0A8B7X238
uniprot id: A0A8B7X243
uniprot id: A0A8B7X248
uniprot id: A0A8B7X253
names: Similarity
messages: Belongs to the LRRFIP family.

30608:LOC105866826
gene id: 30608:LOC105866826
uniprot id: A0A8B7FS86
names: Similarity
messages: Belongs to the SPATA31 family.

30608:NPAS3
gene id: 30608:NPAS3
uniprot id: A0A8B7GYU2
uniprot id: A0A8B7GYU4
uniprot id: A0A8B7GYU8
uniprot id: A0A8B7GYU9
uniprot id: A0A8B7GYV3
uniprot id: A0A8B7GYV4
uniprot id: A0A8B7GYW8
uniprot id: A0A8B7GYY5
uniprot id: A0A8B7GYZ0
uniprot id: A0A8B7GYZ5
uniprot id: A0A8B7GZ00
uniprot id: A0A8B7H0R0
uniprot id: A0A8B7H0R5
uniprot id: A0A8B7H0S0
uniprot id: A0A8B7H0S4
uniprot id: A0A8C5VI04
names: Subcellular Location Annotation
messages: Nucleus

30608:MARK2
gene id: 30608:MARK2
uniprot id: A0A8B7H9F2
uniprot id: A0A8B7H9F8
uniprot id: A0A8B7H9F9
uniprot id: A0A8B7H9G1
uniprot id: A0A8B7H9G2
uniprot id: A0A8B7H9G4
uniprot id: A0A8B7H9G6
uniprot id: A0A8B7H9H2
uniprot id: A0A8B7H9H6
uniprot id: A0A8B7HC80
uniprot id: A0A8B7HC86
uniprot id: A0A8B7X2Q9
uniprot id: A0A8B7X2R8
uniprot id: A0A8B7X460
uniprot id: A0A8C5VQ89
uniprot id: A0A8C6EDH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

30608:LOC105879235
gene id: 30608:LOC105879235
uniprot id: A0A8B7HD63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:G6PC2
gene id: 30608:G6PC2
uniprot id: A0A8C5Y7G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

30608:RNF112
gene id: 30608:RNF112
uniprot id: A0A8B7F6M4
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

30608:LSM6
gene id: 30608:LSM6
uniprot id: A0A8B7HNC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

30608:LOC105862319
gene id: 30608:LOC105862319
uniprot id: A0A8B7F7W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

30608:LOC105879883
gene id: 30608:LOC105879883
uniprot id: A0A8B7HFW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

30608:LOC105858834
gene id: 30608:LOC105858834
uniprot id: A0A8B7ERE7
names: Similarity
messages: Belongs to the mab-21 family.

30608:ABCB5
gene id: 30608:ABCB5
uniprot id: A0A8B7XDE4
names: Subcellular Location Annotation
messages: Membrane

30608:CD3G
gene id: 30608:CD3G
uniprot id: A0A8B7GZC8
uniprot id: A0A8B7GZD1
uniprot id: A0A8B7GZH8
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The TCR-CD3 complex is composed of a CD3D/CD3E and a CD3G/CD3E heterodimers that preferentially associate with TCRalpha and TCRbeta, respectively, to form TCRalpha/CD3E/CD3G and TCRbeta/CD3G/CD3E trimers. In turn, the hexamer interacts with CD3Z homodimer to form the TCR-CD3 complex. Alternatively, TCRalpha and TCRbeta can be replaced by TCRgamma and TCRdelta.

30608:LOC105870534
gene id: 30608:LOC105870534
uniprot id: A0A8B7XB96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

30608:MFNG
gene id: 30608:MFNG
uniprot id: A0A8B7HYY8
uniprot id: A0A8B7HZC9
uniprot id: A0A8C5XHD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:ASL
gene id: 30608:ASL
uniprot id: A0A8C5VL50
names: Similarity
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

30608:KCNK4
gene id: 30608:KCNK4
uniprot id: A0A8B7H9M2
uniprot id: A0A8B7H9M4
uniprot id: A0A8B7H9M7
uniprot id: A0A8B7H9N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

30608:SIRT3
gene id: 30608:SIRT3
uniprot id: A0A8B7X4I2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.
messages: NAD-dependent protein deacetylase.

30608:EDN2
gene id: 30608:EDN2
uniprot id: A0A8C6EIH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

30608:MAST2
gene id: 30608:MAST2
uniprot id: A0A8B7H512
uniprot id: A0A8B7H516
uniprot id: A0A8B7H518
uniprot id: A0A8B7H521
uniprot id: A0A8B7H522
uniprot id: A0A8B7H523
uniprot id: A0A8B7H526
uniprot id: A0A8B7H527
uniprot id: A0A8B7H528
uniprot id: A0A8B7H531
uniprot id: A0A8B7H550
uniprot id: A0A8B7H555
uniprot id: A0A8B7H560
uniprot id: A0A8B7H7C2
uniprot id: A0A8B7H7C8
uniprot id: A0A8B7H7D6
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

30608:TRMO
gene id: 30608:TRMO
uniprot id: A0A8B7GNM2
uniprot id: A0A8B7XB05
uniprot id: A0A8B7XBT9
uniprot id: A0A8C5Y4D6
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

30608:PPP3CB
gene id: 30608:PPP3CB
uniprot id: A0A8B7G0D3
uniprot id: A0A8B7G0F1
uniprot id: A0A8B7G0F6
uniprot id: A0A8B7G0G2
uniprot id: A0A8B7G0G7
uniprot id: A0A8B7G1B5
uniprot id: A0A8B7G1Q2
uniprot id: A0A8B7G1Q7
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

30608:FGF11
gene id: 30608:FGF11
uniprot id: A0A8B7H626
uniprot id: A0A8B7H635
uniprot id: A0A8B7H643
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

30608:LOC105878827
gene id: 30608:LOC105878827
uniprot id: A0A8B7HB95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LMNA
gene id: 30608:LMNA
uniprot id: A0A8B7GJW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: Nucleus lamina

30608:PWP2
gene id: 30608:PWP2
uniprot id: A0A8B7HCF5
uniprot id: A0A8C5Y3V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PWP2 family.
messages: nucleolus

30608:UBE2H
gene id: 30608:UBE2H
uniprot id: A0A8B7I1Y4
uniprot id: A0A8B7I4U8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:TMEM94
gene id: 30608:TMEM94
uniprot id: A0A8B7HBS1
uniprot id: A0A8B7HEE9
uniprot id: A0A8B7WNK6
uniprot id: A0A8C5USZ9
uniprot id: A0A8C5VKL0
names: Subcellular Location Annotation
messages: Membrane

30608:MAPK8IP1
gene id: 30608:MAPK8IP1
uniprot id: A0A8C5VFD4
uniprot id: A0A8C5VHK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JIP scaffold family.
messages: Cytoplasm

30608:LOC105863154
gene id: 30608:LOC105863154
uniprot id: A0A8B7FB81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:AGO2
gene id: 30608:AGO2
uniprot id: A0A8B7EAR9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argonaute family. Ago subfamily.
messages: Hydroxylated. 4-hydroxylation appears to enhance protein stability but is not required for miRNA-binding or endonuclease activity.
messages: Interacts with DICER1 through its Piwi domain and with TARBP2 during assembly of the RNA-induced silencing complex (RISC). Together, DICER1, AGO2 and TARBP2 constitute the trimeric RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC). Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. Note however that the term RISC has also been used to describe the trimeric RLC/miRLC. The formation of RISC complexes containing siRNAs rather than miRNAs appears to occur independently of DICER1. Interacts with AGO1. Also interacts with DDB1, DDX5, DDX6, DDX20, DHX30, DHX36, DDX47, DHX9, ELAVL, FXR1, GEMIN4, HNRNPF, IGF2BP1, ILF3, IMP8, MATR3, PABPC1, PRMT5, P4HA1, P4HB, RBM4, SART3, TNRC6A, TNRC6B, UPF1 and YBX1. Interacts with the P-body components DCP1A and XRN1. Associates with polysomes and messenger ribonucleoproteins (mNRPs). Interacts with RBM4; the interaction is modulated under stress-induced conditions, occurs under both cell proliferation and differentiation conditions and in an RNA-and phosphorylation-independent manner. Interacts with LIMD1, WTIP and AJUBA. Interacts with TRIM71. Interacts with APOBEC3G in an RNA-dependent manner. Interacts with APOBEC3A, APOBEC3C, APOBEC3F and APOBEC3H. Interacts with DICER1, TARBP2, EIF6, MOV10 and RPL7A (60S ribosome subunit); they form a large RNA-induced silencing complex (RISC). Interacts with FMR1. Interacts with ZFP36.
messages: Nucleus
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the mRNA specifically by AGO2. Binding of RISC to a partially complementary mRNA results in silencing through inhibition of translation, and this is independent of endonuclease activity. May inhibit translation initiation by binding to the 7-methylguanosine cap, thereby preventing the recruitment of the translation initiation factor eIF4-E. May also inhibit translation initiation via interaction with EIF6, which itself binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit. The inhibition of translational initiation leads to the accumulation of the affected mRNA in cytoplasmic processing bodies (P-bodies), where mRNA degradation may subsequently occur. In some cases RISC-mediated translational repression is also observed for miRNAs that perfectly match the 3' untranslated region (3'-UTR). Can also up-regulate the translation of specific mRNAs under certain growth conditions. Binds to the AU element of the 3'-UTR of the TNF (TNF-alpha) mRNA and up-regulates translation under conditions of serum starvation. Also required for transcriptional gene silencing (TGS), in which short RNAs known as antigene RNAs or agRNAs direct the transcriptional repression of complementary promoter regions.
messages: The Piwi domain may perform RNA cleavage by a mechanism similar to that of RNase H. However, while RNase H utilizes a triad of Asp-Asp-Glu (DDE) for metal ion coordination, this protein appears to utilize a triad of Asp-Asp-His (DDH).

30608:NUP210L
gene id: 30608:NUP210L
uniprot id: A0A8B7X209
names: Similarity
messages: Belongs to the NUP210 family.

30608:DPM2
gene id: 30608:DPM2
uniprot id: A0A8C5XFJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.

30608:ZFPM1
gene id: 30608:ZFPM1
uniprot id: A0A8B7WSU9
names: Subcellular Location Annotation
messages: Nucleus

30608:SEC16A
gene id: 30608:SEC16A
uniprot id: A0A8B7HJC8
uniprot id: A0A8B7HJD0
uniprot id: A0A8B7HJD1
uniprot id: A0A8B7HKG7
uniprot id: A0A8B7HLX5
uniprot id: A0A8B7HLY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
messages: SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.

30608:ASNA1
gene id: 30608:ASNA1
uniprot id: A0A8C5Y4R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Homodimer. Component of a transmembrane domain recognition complex (TRC). Interacts with SERP1 and SEC61B. Interacts with WRB.
messages: nucleolus

30608:CNNM4
gene id: 30608:CNNM4
uniprot id: A0A8B7HW97
uniprot id: A0A8B7HWB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Cell membrane
messages: Membrane
messages: Metal transporter.

30608:OTULIN
gene id: 30608:OTULIN
uniprot id: A0A8B7I4G5
uniprot id: A0A8B7I4G8
uniprot id: A0A8B7I6H0
uniprot id: A0A8B7I7I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

30608:P2RY13
gene id: 30608:P2RY13
uniprot id: A0A8B7HLA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TWISTNB
gene id: 30608:TWISTNB
uniprot id: A0A8B7HH16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA43 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

30608:DEFB116
gene id: 30608:DEFB116
uniprot id: A0A8B7WQP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

30608:DNAJC27
gene id: 30608:DNAJC27
uniprot id: A0A8C5W702
names: Function
names: Subunit
messages: GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling.
messages: Interacts directly with MAPK1 (wild-type and kinase-deficient forms). Interacts directly (in GTP-bound form) with MAP2K1 (wild-type and kinase-deficient forms).

30608:DOCK3
gene id: 30608:DOCK3
uniprot id: A0A8B7GTX9
uniprot id: A0A8B7GTY4
uniprot id: A0A8B7GU33
uniprot id: A0A8B7GU38
uniprot id: A0A8B7GU58
uniprot id: A0A8B7GVR3
uniprot id: A0A8B7GVR8
uniprot id: A0A8B7WL29
names: Similarity
messages: Belongs to the DOCK family.

30608:MMP2
gene id: 30608:MMP2
uniprot id: A0A8B7FR45
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: extracellular matrix

30608:NHS
gene id: 30608:NHS
uniprot id: A0A8B7HQN8
uniprot id: A0A8B7HSH2
uniprot id: A0A8B7HT17
names: Similarity
messages: Belongs to the NHS family.

30608:MAF1
gene id: 30608:MAF1
uniprot id: A0A8C5YEI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

30608:TLR7
gene id: 30608:TLR7
uniprot id: A0A8B7HQX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Endoplasmic reticulum membrane
messages: Lysosome
messages: Membrane
messages: phagosome

30608:POLR2M
gene id: 30608:POLR2M
uniprot id: A0A8B7HN11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRINL1 family.
messages: Nucleus

30608:VAMP1
gene id: 30608:VAMP1
uniprot id: A0A8B7G243
uniprot id: A0A8B7G3I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

30608:GOLM1
gene id: 30608:GOLM1
uniprot id: A0A8B7HX28
uniprot id: A0A8B7HZ67
uniprot id: A0A8B7HZM3
uniprot id: A0A8C5XF61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

30608:SNCA
gene id: 30608:SNCA
uniprot id: A0A8B7H0B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synuclein family.
messages: Membrane
messages: Nucleus
messages: Secreted
messages: Synapse
messages: axon

30608:PFDN6
gene id: 30608:PFDN6
uniprot id: A0A8B7X475
names: Function
names: Similarity
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

30608:COG1
gene id: 30608:COG1
uniprot id: A0A8B7FRH5
names: Similarity
messages: Belongs to the COG1 family.

30608:ZNF197
gene id: 30608:ZNF197
uniprot id: A0A8C5XM65
names: Subcellular Location Annotation
messages: Nucleus

30608:JUND
gene id: 30608:JUND
uniprot id: A0A8B7WVE6
names: Similarity
messages: Belongs to the bZIP family. Jun subfamily.

30608:VASN
gene id: 30608:VASN
uniprot id: A0A8B7EVA9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:PLSCR1
gene id: 30608:PLSCR1
uniprot id: A0A8B7G6F0
uniprot id: A0A8B7G7K9
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

30608:LOC105866844
gene id: 30608:LOC105866844
uniprot id: A0A8B7WTH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-5A synthase family.
messages: Cytoplasm

30608:WNT7B
gene id: 30608:WNT7B
uniprot id: A0A8B7FUG2
uniprot id: A0A8B7FV99
uniprot id: A0A8C5XWD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

30608:SLC52A3
gene id: 30608:SLC52A3
uniprot id: A0A8B7FQ01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

30608:ISYNA1
gene id: 30608:ISYNA1
uniprot id: A0A8C5XKW8
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

30608:IFRD1
gene id: 30608:IFRD1
uniprot id: A0A8B7EBD9
uniprot id: A0A8C6EKP4
names: Similarity
messages: Belongs to the IFRD family.

30608:DLG1
gene id: 30608:DLG1
uniprot id: A0A8C5YHY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Membrane

30608:SSH2
gene id: 30608:SSH2
uniprot id: A0A8B7EMI4
uniprot id: A0A8B7EMQ5
uniprot id: A0A8B7EPR4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

30608:LOC105866929
gene id: 30608:LOC105866929
uniprot id: A0A8B7FTH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

30608:RAD9B
gene id: 30608:RAD9B
uniprot id: A0A8B7WTA9
names: Similarity
messages: Belongs to the rad9 family.

30608:ITGA4
gene id: 30608:ITGA4
uniprot id: A0A8B7HVJ3
uniprot id: A0A8C5V037
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

30608:GYS1
gene id: 30608:GYS1
uniprot id: A0A8B7FLU3
uniprot id: A0A8B7FM35
uniprot id: A0A8B7FM39
uniprot id: A0A8C5YD38
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

30608:MYCBP
gene id: 30608:MYCBP
uniprot id: A0A8B7HH22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AMY1 family.
messages: Nucleus

30608:PKIB
gene id: 30608:PKIB
uniprot id: A0A8B7H8M2
uniprot id: A0A8B7H8N4
uniprot id: A0A8B7X4W6
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

30608:FOXA1
gene id: 30608:FOXA1
uniprot id: A0A8C5W3R4
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105869622
gene id: 30608:LOC105869622
uniprot id: A0A8B7G4H0
names: Similarity
messages: Belongs to the PRAME family.

30608:SHQ1
gene id: 30608:SHQ1
uniprot id: A0A8C5W7M0
names: Similarity
messages: Belongs to the SHQ1 family.

30608:FTO
gene id: 30608:FTO
uniprot id: A0A8B7GX31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fto family.
messages: Cytoplasm
messages: Nucleus speckle

30608:ST3GAL4
gene id: 30608:ST3GAL4
uniprot id: A0A8B7GW63
uniprot id: A0A8B7GW78
uniprot id: A0A8B7GW83
uniprot id: A0A8B7GW84
uniprot id: A0A8B7GY01
uniprot id: A0A8B7GY08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

30608:KCNC1
gene id: 30608:KCNC1
uniprot id: A0A8C5XLN5
names: Subcellular Location Annotation
messages: Membrane

30608:MAN2B1
gene id: 30608:MAN2B1
uniprot id: A0A8B7I6Z3
uniprot id: A0A8C5W0U8
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

30608:ACSL5
gene id: 30608:ACSL5
uniprot id: A0A8B7GUG6
uniprot id: A0A8B7GUH7
uniprot id: A0A8B7GUJ0
uniprot id: A0A8B7GUJ1
uniprot id: A0A8B7GUN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion outer membrane

30608:GAPDHS
gene id: 30608:GAPDHS
uniprot id: A0A8B7H2P3
uniprot id: A0A8B7H2P7
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

30608:SLCO5A1
gene id: 30608:SLCO5A1
uniprot id: A0A8B7GSG0
uniprot id: A0A8B7GSP4
uniprot id: A0A8B7X9P4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:GALNT14
gene id: 30608:GALNT14
uniprot id: A0A8B7HZV5
uniprot id: A0A8B7HZV6
uniprot id: A0A8B7HZV9
uniprot id: A0A8B7I1Z2
uniprot id: A0A8B7I2K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

30608:LOC105884139
gene id: 30608:LOC105884139
uniprot id: A0A8B7X2X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ACSM3
gene id: 30608:ACSM3
uniprot id: A0A8B7I498
uniprot id: A0A8B7I4C3
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

30608:PPP3CA
gene id: 30608:PPP3CA
uniprot id: A0A8B7WXH2
uniprot id: A0A8B7WXW7
uniprot id: A0A8B7WYB2
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

30608:LOC105868767
gene id: 30608:LOC105868767
uniprot id: A0A8B7WP47
names: Subcellular Location Annotation
messages: Nucleus

30608:ACP5
gene id: 30608:ACP5
uniprot id: I1E390
names: Cofactor
messages: Binds 2 iron ions per subunit.

30608:PRM2
gene id: 30608:PRM2
uniprot id: A0A8B7HQU5
uniprot id: A0A8C5VJQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protamine P2 family.
messages: Interacts with TDRP.
messages: Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex.

30608:GATAD1
gene id: 30608:GATAD1
uniprot id: A0A8B7HDS3
names: Subcellular Location Annotation
messages: Nucleus

30608:EEF2K
gene id: 30608:EEF2K
uniprot id: A0A8C5V537
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. Alpha-type protein kinase family.
messages: Monomer or homodimer.
messages: Undergoes calcium/calmodulin-dependent intramolecular autophosphorylation, and this results in it becoming partially calcium/calmodulin-independent.

30608:ADGRL1
gene id: 30608:ADGRL1
uniprot id: A0A8B7FWT3
uniprot id: A0A8B7FWZ8
uniprot id: A0A8B7FXR4
names: Subcellular Location Annotation
messages: Membrane

30608:NLGN4X
gene id: 30608:NLGN4X
uniprot id: A0A8B7WYZ9
uniprot id: A0A8C5Y6F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

30608:PIN4
gene id: 30608:PIN4
uniprot id: A0A8B7HPR3
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.

30608:UBE4A
gene id: 30608:UBE4A
uniprot id: A0A8B7X437
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm
messages: The U-box domain is required for the ubiquitin protein ligase activity.
messages: Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. Also functions as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. Mediates 'Lys-48'-linked polyubiquitination of substrates.

30608:LOC105858289
gene id: 30608:LOC105858289
uniprot id: A0A8B7EP75
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:DNAH17
gene id: 30608:DNAH17
uniprot id: A0A8C5V2J5
names: Similarity
messages: Belongs to the dynein heavy chain family.

30608:MOB2
gene id: 30608:MOB2
uniprot id: A0A8B7GPD7
uniprot id: A0A8B7GPE1
names: Similarity
messages: Belongs to the MOB1/phocein family.

30608:LOC105863156
gene id: 30608:LOC105863156
uniprot id: A0A8B7FBA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105863860
gene id: 30608:LOC105863860
uniprot id: A0A8B7FF29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative pheromone receptor.

30608:ISCU
gene id: 30608:ISCU
uniprot id: A0A8B7FSJ9
uniprot id: A0A8B7FTG9
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Mitochondrial scaffold protein, of the core iron-sulfur cluster (ISC) assembly complex, that provides the structural architecture on which the [2Fe-2S] clusters are assembled. The core iron-sulfur cluster (ISC) assembly complex is involved in the de novo synthesis of a [2Fe-2S] cluster, the first step of the mitochondrial iron-sulfur protein biogenesis. This process is initiated by the cysteine desulfurase complex (NFS1:LYRM4:NDUFAB1) that produces persulfide which is delivered on the scaffold protein ISCU in a FXN-dependent manner. Then this complex is stabilized by FDX2 which provides reducing equivalents to accomplish the [2Fe-2S] cluster assembly. Finally, the [2Fe-2S] cluster is transferred from ISCU to chaperone proteins, including HSCB, HSPA9 and GLRX5. Exists as two slow interchanging conformational states, a structured (S) and disordered (D) form. May modulate NFS1 desulfurase activity in a zinc-dependent manner. Modulates the interaction between FXN and the cysteine desulfurase complex.

30608:TCFL5
gene id: 30608:TCFL5
uniprot id: A0A8B7WQR4
names: Subcellular Location Annotation
messages: Nucleus

30608:STOM
gene id: 30608:STOM
uniprot id: A0A8B7GUX4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

30608:ADAM22
gene id: 30608:ADAM22
uniprot id: A0A8B7HDJ9
uniprot id: A0A8B7HDK3
uniprot id: A0A8B7HDK6
uniprot id: A0A8B7HDK7
uniprot id: A0A8B7HDL1
uniprot id: A0A8B7HDL6
uniprot id: A0A8B7HDT5
uniprot id: A0A8B7HDU4
uniprot id: A0A8B7HG74
uniprot id: A0A8B7HG80
uniprot id: A0A8B7XEF9
uniprot id: A0A8C5VGY7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:EXOC5
gene id: 30608:EXOC5
uniprot id: A0A8B7HST3
uniprot id: A0A8C5XK05
names: Similarity
messages: Belongs to the SEC10 family.

30608:ALDH1A3
gene id: 30608:ALDH1A3
uniprot id: A0A8C5VD69
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

30608:PRICKLE1
gene id: 30608:PRICKLE1
uniprot id: A0A8B7EXY3
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

30608:GRM1
gene id: 30608:GRM1
uniprot id: A0A8B7X6Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

30608:LOC105865649
gene id: 30608:LOC105865649
uniprot id: A0A8B7FMC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Odorant receptor.

30608:BVES
gene id: 30608:BVES
uniprot id: A0A8B7FKU7
names: Similarity
messages: Belongs to the popeye family.

30608:SMUG1
gene id: 30608:SMUG1
uniprot id: A0A8B7GC35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. SMUG1 family.
messages: Nucleus

30608:RPGRIP1
gene id: 30608:RPGRIP1
uniprot id: A0A8B7X2G5
names: Similarity
messages: Belongs to the RPGRIP1 family.

30608:BTG2
gene id: 30608:BTG2
uniprot id: A0A8C5XTJ2
names: Similarity
messages: Belongs to the BTG family.

30608:CTU1
gene id: 30608:CTU1
uniprot id: A0A8B7FLY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Component of a complex at least composed of URM1, CTU2/NCS2 and CTU1/ATPBD3. May form a heterodimer with CTU2/NCS2.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

30608:OSBPL9
gene id: 30608:OSBPL9
uniprot id: A0A8B7H5F3
uniprot id: A0A8B7H5F6
uniprot id: A0A8B7H5F7
uniprot id: A0A8B7H5F8
uniprot id: A0A8B7H5G0
uniprot id: A0A8B7H5G2
uniprot id: A0A8B7H5G3
uniprot id: A0A8B7H5G7
uniprot id: A0A8B7H5G8
uniprot id: A0A8B7H5H4
uniprot id: A0A8B7H5J0
uniprot id: A0A8B7H5J5
uniprot id: A0A8B7H5J8
uniprot id: A0A8B7H5K2
uniprot id: A0A8B7H7T0
uniprot id: A0A8B7H7U2
names: Similarity
messages: Belongs to the OSBP family.

30608:CHMP2A
gene id: 30608:CHMP2A
uniprot id: A0A8B7FHD8
uniprot id: A0A8C5UNC5
names: Similarity
messages: Belongs to the SNF7 family.

30608:LOC105876749
gene id: 30608:LOC105876749
uniprot id: A0A8B7H1G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

30608:LOC105866362
gene id: 30608:LOC105866362
uniprot id: A0A8B7FQ96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:HCRTR1
gene id: 30608:HCRTR1
uniprot id: A0A8B7XCX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:KHDRBS3
gene id: 30608:KHDRBS3
uniprot id: A0A8B7XA20
uniprot id: A0A8B7XA21
uniprot id: A0A8B7XAT4
uniprot id: A0A8B7XC71
names: Similarity
messages: Belongs to the KHDRBS family.

30608:ABCC12
gene id: 30608:ABCC12
uniprot id: A0A8B7I1F3
uniprot id: A0A8B7I1F4
uniprot id: A0A8B7I494
uniprot id: A0A8B7WSM3
names: Subcellular Location Annotation
messages: Membrane

30608:CAMK2G
gene id: 30608:CAMK2G
uniprot id: A0A8B7G0U5
uniprot id: A0A8B7G0V0
uniprot id: A0A8B7G0V4
uniprot id: A0A8B7G0V5
uniprot id: A0A8B7G0V9
uniprot id: A0A8B7G0W0
uniprot id: A0A8B7G0W1
uniprot id: A0A8B7G0W4
uniprot id: A0A8B7G0W5
uniprot id: A0A8B7G0X0
uniprot id: A0A8B7G1R6
uniprot id: A0A8B7G270
uniprot id: A0A8B7G275
uniprot id: A0A8B7G280
uniprot id: A0A8B7WM57
uniprot id: A0A8B7WM61
uniprot id: A0A8B7WMB3
uniprot id: A0A8C5VYQ4
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

30608:LOC105858377
gene id: 30608:LOC105858377
uniprot id: A0A8B7ER64
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

30608:LTA
gene id: 30608:LTA
uniprot id: A0A8B7EQP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tumor necrosis factor family.
messages: Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.
messages: Homotrimer, and heterotrimer of either two LTB and one LTA subunits or (less prevalent) two LTA and one LTB subunits. Interacts with TNFRSF14.
messages: Membrane
messages: Secreted

30608:LOC105858527
gene id: 30608:LOC105858527
uniprot id: A0A8B7EQ47
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

30608:LOC105866648
gene id: 30608:LOC105866648
uniprot id: A0A8B7FRB7
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

30608:CTPS1
gene id: 30608:CTPS1
uniprot id: A0A8B7EAM0
uniprot id: A0A8C5XX89
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

30608:ALDH2
gene id: 30608:ALDH2
uniprot id: A0A8C5V7F1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

30608:LOC105865686
gene id: 30608:LOC105865686
uniprot id: A0A8B7FME2
uniprot id: A0A8B7FMK5
uniprot id: A0A8B7WVZ3
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105875315
gene id: 30608:LOC105875315
uniprot id: A0A8B7GW14
names: Subcellular Location Annotation
messages: Membrane

30608:DMPK
gene id: 30608:DMPK
uniprot id: A0A8B7G424
uniprot id: A0A8B7G430
uniprot id: A0A8B7G432
uniprot id: A0A8B7G448
uniprot id: A0A8B7G454
uniprot id: A0A8B7G4W7
uniprot id: A0A8B7G5G1
uniprot id: A0A8B7G5G6
uniprot id: A0A8C5XFV9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.

30608:LOC105874766
gene id: 30608:LOC105874766
uniprot id: A0A8C5VXV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

30608:CFL2
gene id: 30608:CFL2
uniprot id: A0A8B7EC78
uniprot id: A0A8C5VLK7
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

30608:ATP6V0A1
gene id: 30608:ATP6V0A1
uniprot id: A0A8B7ETX9
uniprot id: A0A8B7ETY5
uniprot id: A0A8B7EVW8
uniprot id: A0A8B7EVY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

30608:LOC105856762
gene id: 30608:LOC105856762
uniprot id: A0A8B7EHJ9
uniprot id: A0A8B7EIK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane

30608:LOC105874781
gene id: 30608:LOC105874781
uniprot id: A0A8B7XCQ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:GNB4
gene id: 30608:GNB4
uniprot id: A0A8B7EDJ3
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

30608:TUSC5
gene id: 30608:TUSC5
uniprot id: A0A8B7EMB7
names: Similarity
messages: Belongs to the CD225/Dispanin family.

30608:RPL27
gene id: 30608:RPL27
uniprot id: A0A8C5V1X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL27 family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum

30608:ABCC9
gene id: 30608:ABCC9
uniprot id: A0A8B7X724
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with KCNJ11.
messages: Membrane

30608:ATP6V0D2
gene id: 30608:ATP6V0D2
uniprot id: A0A8C5VZC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

30608:LOC105862267
gene id: 30608:LOC105862267
uniprot id: A0A8B7F7P1
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105861308
gene id: 30608:LOC105861308
uniprot id: A0A8B7F3U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ACTRT3
gene id: 30608:ACTRT3
uniprot id: A0A8B7HCU9
names: Similarity
messages: Belongs to the actin family.

30608:NTRK1
gene id: 30608:NTRK1
uniprot id: A0A8B7GJN4
uniprot id: A0A8B7GKA6
uniprot id: A0A8B7GKT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

30608:LOC105883404
gene id: 30608:LOC105883404
uniprot id: A0A8B7HV18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CCL1
gene id: 30608:CCL1
uniprot id: A0A8B7ESW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

30608:KCNE2
gene id: 30608:KCNE2
uniprot id: A0A8B7F3E5
names: Similarity
messages: Belongs to the potassium channel KCNE family.

30608:ATP13A1
gene id: 30608:ATP13A1
uniprot id: A0A8B7EPF9
uniprot id: A0A8B7EPG7
uniprot id: A0A8C5XXX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

30608:SLC27A3
gene id: 30608:SLC27A3
uniprot id: A0A8B7I8V8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

30608:FAM114A2
gene id: 30608:FAM114A2
uniprot id: A0A8B7G4V3
names: Similarity
messages: Belongs to the FAM114 family.

30608:GUCY1A3
gene id: 30608:GUCY1A3
uniprot id: A0A8C5V3N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

30608:AU129 gp11
gene id: 30608:AU129_gp11
uniprot id: A0A0U2S4M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

30608:CDH9
gene id: 30608:CDH9
uniprot id: A0A8B7GDA7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

30608:MLNR
gene id: 30608:MLNR
uniprot id: A0A8B7EE64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:FAM129B
gene id: 30608:FAM129B
uniprot id: A0A8B7GVF3
names: Similarity
messages: Belongs to the Niban family.

30608:SLC4A4
gene id: 30608:SLC4A4
uniprot id: A0A8B7HTJ2
uniprot id: A0A8B7HTJ7
uniprot id: A0A8B7HTK2
uniprot id: A0A8B7HTL0
uniprot id: A0A8B7HTL3
uniprot id: A0A8B7HTL9
uniprot id: A0A8B7HVL5
uniprot id: A0A8B7HVL9
uniprot id: A0A8B7HVM4
uniprot id: A0A8B7HVT6
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

30608:OXA1L
gene id: 30608:OXA1L
uniprot id: A0A8C5VPB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

30608:ASB16
gene id: 30608:ASB16
uniprot id: A0A8B7HVM9
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

30608:LOC105871425
gene id: 30608:LOC105871425
uniprot id: A0A8B7X6B8
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

30608:LOC109729268
gene id: 30608:LOC109729268
uniprot id: A0A8B7WKS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

30608:EXTL2
gene id: 30608:EXTL2
uniprot id: A0A8B7F7L7
uniprot id: A0A8B7F7W0
uniprot id: A0A8C5XVX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:DMTN
gene id: 30608:DMTN
uniprot id: A0A8B7EJI4
uniprot id: A0A8B7EJI7
uniprot id: A0A8B7ELJ0
uniprot id: A0A8B7ELJ4
names: Subcellular Location Annotation
messages: Cytoplasm

30608:ITPRIPL1
gene id: 30608:ITPRIPL1
uniprot id: A0A8B7HW52
uniprot id: A0A8B7HW64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

30608:LOC105861345
gene id: 30608:LOC105861345
uniprot id: A0A8B7WUR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.
messages: Cell membrane
messages: Membrane

30608:PPP1R1B
gene id: 30608:PPP1R1B
uniprot id: A0A8C5W5A8
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

30608:LTC4S
gene id: 30608:LTC4S
uniprot id: A0A8B7I3N0
uniprot id: A0A8B7I3N3
uniprot id: A0A8B7I3Q0
uniprot id: A0A8B7I5N4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:ELAVL3
gene id: 30608:ELAVL3
uniprot id: A0A8B7WW31
uniprot id: A0A8B7WWT0
names: Similarity
messages: Belongs to the RRM elav family.

30608:LACTB2
gene id: 30608:LACTB2
uniprot id: A0A8B7GU42
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.

30608:ABCA3
gene id: 30608:ABCA3
uniprot id: A0A8C5XHA6
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105860027
gene id: 30608:LOC105860027
uniprot id: A0A8B7EWV4
uniprot id: A0A8B7WWY1
uniprot id: A0A8B7WXQ6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:FAM166B
gene id: 30608:FAM166B
uniprot id: A0A8B7XBX6
uniprot id: A0A8B7XCT0
uniprot id: A0A8B7XDA0
names: Similarity
messages: Belongs to the CIMIP2 family.

30608:SLC25A14
gene id: 30608:SLC25A14
uniprot id: A0A8B7FCG0
uniprot id: A0A8B7FCG9
uniprot id: A0A8B7FCN2
uniprot id: A0A8B7FD81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:BEX5
gene id: 30608:BEX5
uniprot id: A0A8B7FXV9
names: Similarity
messages: Belongs to the BEX family.

30608:NR5A1
gene id: 30608:NR5A1
uniprot id: A0A8B7GV83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

30608:GALNT5
gene id: 30608:GALNT5
uniprot id: A0A8B7ESQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

30608:SOSTDC1
gene id: 30608:SOSTDC1
uniprot id: A0A8B7HHV4
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:PER1
gene id: 30608:PER1
uniprot id: A0A8B7H434
uniprot id: A0A8B7H6D1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:RPL9
gene id: 30608:RPL9
uniprot id: A0A8B7WR52
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Component of the large ribosomal subunit.

30608:SULT2A1
gene id: 30608:SULT2A1
uniprot id: A0A8B7G4D3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

30608:SERPINB11
gene id: 30608:SERPINB11
uniprot id: A0A8C5VP84
names: Similarity
messages: Belongs to the serpin family.

30608:CAPN1
gene id: 30608:CAPN1
uniprot id: A0A8B7H9X9
names: Similarity
messages: Belongs to the peptidase C2 family.

30608:NR6A1
gene id: 30608:NR6A1
uniprot id: A0A8B7GV36
uniprot id: A0A8B7GV55
uniprot id: A0A8B7GWV1
uniprot id: A0A8C5UN52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

30608:ADGRE3
gene id: 30608:ADGRE3
uniprot id: A0A8B7WX47
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:NUP62CL
gene id: 30608:NUP62CL
uniprot id: A0A8B7FDM0
uniprot id: A0A8B7FEM7
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

30608:CAMK2N1
gene id: 30608:CAMK2N1
uniprot id: A0A8B7I0Y8
names: Similarity
messages: Belongs to the CAMK2N family.

30608:GPR156
gene id: 30608:GPR156
uniprot id: A0A8B7HFZ6
uniprot id: A0A8B7HG31
uniprot id: A0A8B7X5N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

30608:BGLAP
gene id: 30608:BGLAP
uniprot id: A0A8C5YDC6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the osteocalcin/matrix Gla protein family.
messages: Binds strongly to apatite and calcium.
messages: Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.
messages: Secreted

30608:ALDOB
gene id: 30608:ALDOB
uniprot id: A0A8B7GP62
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

30608:CAMK2B
gene id: 30608:CAMK2B
uniprot id: A0A8B7EPL3
uniprot id: A0A8B7EPL7
uniprot id: A0A8B7EPM0
uniprot id: A0A8B7EPM4
uniprot id: A0A8B7EPR1
uniprot id: A0A8B7EPR6
uniprot id: A0A8B7ER90
uniprot id: A0A8B7ER95
uniprot id: A0A8B7ERS0
uniprot id: A0A8B7ERS3
uniprot id: A0A8C5XVC9
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

30608:FBLN1
gene id: 30608:FBLN1
uniprot id: A0A8C5V5U5
uniprot id: A0A8C5XWX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fibulin family.
messages: Homomultimerizes and interacts with various extracellular matrix components.
messages: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:ADGRA1
gene id: 30608:ADGRA1
uniprot id: A0A8B7F3D4
names: Subcellular Location Annotation
messages: Membrane

30608:EPHB2
gene id: 30608:EPHB2
uniprot id: A0A8B7WMT3
uniprot id: A0A8B7WNY9
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105884140
gene id: 30608:LOC105884140
uniprot id: A0A8B7HYI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105855618
gene id: 30608:LOC105855618
uniprot id: A0A8B7XC86
names: Similarity
messages: Belongs to the FBPase class 1 family.

30608:VTI1A
gene id: 30608:VTI1A
uniprot id: A0A8B7GUP9
uniprot id: A0A8B7GUS6
uniprot id: A0A8B7GUU9
uniprot id: A0A8B7GUW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

30608:C8A
gene id: 30608:C8A
uniprot id: A0A8C5UKU7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

30608:IL6ST
gene id: 30608:IL6ST
uniprot id: A0A8B7XE40
uniprot id: A0A8B7XEM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

30608:LOC105861469
gene id: 30608:LOC105861469
uniprot id: A0A8B7F3B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

30608:DLD
gene id: 30608:DLD
uniprot id: A0A8C5VWP1
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.
messages: acrosome
messages: flagellum

30608:PLA2G2A
gene id: 30608:PLA2G2A
uniprot id: A0A8B7I0P8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

30608:LOC105866477
gene id: 30608:LOC105866477
uniprot id: A0A8B7FQR8
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

30608:LOC105860315
gene id: 30608:LOC105860315
uniprot id: A0A8B7EY75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PPP1R11
gene id: 30608:PPP1R11
uniprot id: A0A8B7EC43
uniprot id: A0A8B7EED3
names: Subunit
messages: Interacts with TLR2 and UBE2D2.

30608:NDUFB3
gene id: 30608:NDUFB3
uniprot id: A0A8C5Y647
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

30608:FAM110D
gene id: 30608:FAM110D
uniprot id: A0A8B7FCU2
names: Similarity
messages: Belongs to the FAM110 family.

30608:LOC105883806
gene id: 30608:LOC105883806
uniprot id: A0A8B7HZL2
names: Similarity
messages: Belongs to the SPATA31 family.

30608:BFSP1
gene id: 30608:BFSP1
uniprot id: A0A8B7G0S0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cell cortex
messages: cytoskeleton

30608:C5H11orf1
gene id: 30608:C5H11orf1
uniprot id: A0A8B7FA95
uniprot id: A0A8B7FAA1
uniprot id: A0A8B7FAW1
names: Function
names: Subcellular Location Annotation
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
messages: cilium axoneme

30608:ODF2
gene id: 30608:ODF2
uniprot id: A0A8B7GVN5
uniprot id: A0A8B7GVP3
uniprot id: A0A8B7GVP5
uniprot id: A0A8B7GVP6
uniprot id: A0A8B7GVQ5
uniprot id: A0A8B7GVQ7
uniprot id: A0A8B7GVR2
uniprot id: A0A8B7GVR4
uniprot id: A0A8B7GVR6
uniprot id: A0A8B7GVU0
uniprot id: A0A8B7GVW1
uniprot id: A0A8B7GVW6
uniprot id: A0A8B7GXG5
uniprot id: A0A8B7GXH0
uniprot id: A0A8B7GXH5
uniprot id: A0A8B7GXI5
uniprot id: A0A8B7GXJ1
uniprot id: A0A8B7GXJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

30608:LOC105864639
gene id: 30608:LOC105864639
uniprot id: A0A8B7FHW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CCHCR1
gene id: 30608:CCHCR1
uniprot id: A0A8B7ENS9
uniprot id: A0A8B7ENW9
uniprot id: A0A8B7EQB6
uniprot id: A0A8B7X5T7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a regulator of keratinocyte proliferation or differentiation.
messages: Nucleus

30608:BICD1
gene id: 30608:BICD1
uniprot id: A0A8B7I222
uniprot id: A0A8B7I225
uniprot id: A0A8B7I228
uniprot id: A0A8B7I229
uniprot id: A0A8B7I233
uniprot id: A0A8B7I235
uniprot id: A0A8B7I436
uniprot id: A0A8B7I440
uniprot id: A0A8B7I4Z4
uniprot id: A0A8B7I500
uniprot id: A0A8B7I505
uniprot id: A0A8C6EDY8
names: Similarity
messages: Belongs to the BicD family.

30608:LOC105861298
gene id: 30608:LOC105861298
uniprot id: A0A8B7F446
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:KCNK13
gene id: 30608:KCNK13
uniprot id: A0A8B7H261
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

30608:LRP6
gene id: 30608:LRP6
uniprot id: A0A8B7X6R2
uniprot id: A0A8B7X832
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDLR family.
messages: Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes.
messages: Homodimer; disulfide-linked. Forms phosphorylated oligomer aggregates on Wnt-signaling.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:CDK2AP2
gene id: 30608:CDK2AP2
uniprot id: A0A8B7FW17
uniprot id: A0A8C5WBX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDK2AP family.
messages: Nucleus

30608:HTR3A
gene id: 30608:HTR3A
uniprot id: A0A8B7F6Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane

30608:SUSD2
gene id: 30608:SUSD2
uniprot id: A0A8B7F9V0
uniprot id: A0A8B7FA88
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:MON2
gene id: 30608:MON2
uniprot id: A0A8B7HK35
uniprot id: A0A8B7HK38
uniprot id: A0A8B7HK42
uniprot id: A0A8B7HLA4
uniprot id: A0A8C5XPI0
names: Similarity
messages: Belongs to the MON2 family.

30608:NUDT21
gene id: 30608:NUDT21
uniprot id: A0A8B7FQW7
uniprot id: A0A8B7FRG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

30608:CNTD2
gene id: 30608:CNTD2
uniprot id: A0A8B7WUA2
names: Similarity
messages: Belongs to the cyclin family.

30608:DUOX2
gene id: 30608:DUOX2
uniprot id: A0A8B7GHX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
messages: In the N-terminal section; belongs to the peroxidase family.
messages: Membrane

30608:SLC10A7
gene id: 30608:SLC10A7
uniprot id: A0A8B7WKG7
uniprot id: A0A8B7WKG9
uniprot id: A0A8B7WKK5
uniprot id: A0A8C5VTF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Cell membrane
messages: Does not show transport activity towards bile acids or steroid sulfates.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

30608:TAS2R40
gene id: 30608:TAS2R40
uniprot id: A0A8B7GKY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

30608:LOC105874757
gene id: 30608:LOC105874757
uniprot id: A0A8B7WXR5
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

30608:KCNK3
gene id: 30608:KCNK3
uniprot id: A0A8B7HZE0
uniprot id: A0A8B7I1F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

30608:POLR2E
gene id: 30608:POLR2E
uniprot id: A0A8B7F077
uniprot id: A0A8B7F080
uniprot id: A0A8B7F081
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.
messages: Nucleus

30608:ZNF496
gene id: 30608:ZNF496
uniprot id: A0A8B7FHK2
names: Subcellular Location Annotation
messages: Nucleus

30608:FAM187B
gene id: 30608:FAM187B
uniprot id: A0A8B7H2R5
uniprot id: A0A8B7H4X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM187 family.
messages: Membrane

30608:LOC105868755
gene id: 30608:LOC105868755
uniprot id: A0A8B7G174
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MTERF1
gene id: 30608:MTERF1
uniprot id: A0A8B7HDP2
uniprot id: A0A8B7HDP3
uniprot id: A0A8B7HDY7
names: Similarity
messages: Belongs to the mTERF family.

30608:PARP3
gene id: 30608:PARP3
uniprot id: A0A8B7GUA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

30608:TIMM13
gene id: 30608:TIMM13
uniprot id: A0A8B7GPA2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

30608:LOC105884100
gene id: 30608:LOC105884100
uniprot id: A0A8B7HYF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:VDAC1
gene id: 30608:VDAC1
uniprot id: A0A8C5YCU7
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

30608:TSPAN1
gene id: 30608:TSPAN1
uniprot id: A0A8C5UPS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

30608:STARD5
gene id: 30608:STARD5
uniprot id: A0A8B7FG44
names: Function
messages: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.

30608:ACOX3
gene id: 30608:ACOX3
uniprot id: A0A8B7WQ82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

30608:CNTNAP5
gene id: 30608:CNTNAP5
uniprot id: A0A8C5V076
names: Caution
names: Similarity
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:RPL26L1
gene id: 30608:RPL26L1
uniprot id: A0A8B7GF10
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

30608:LOC105864534
gene id: 30608:LOC105864534
uniprot id: A0A8B7FIS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SNUPN
gene id: 30608:SNUPN
uniprot id: A0A8B7E9T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snurportin family.
messages: Cytoplasm
messages: Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
messages: Nucleus

30608:NCOR2
gene id: 30608:NCOR2
uniprot id: A0A8B7WTN4
uniprot id: A0A8B7WTP1
uniprot id: A0A8B7WTP2
uniprot id: A0A8B7WTP7
uniprot id: A0A8B7WTP8
uniprot id: A0A8B7WTQ3
uniprot id: A0A8B7WTQ4
uniprot id: A0A8B7WTQ9
uniprot id: A0A8B7WTV6
uniprot id: A0A8B7WTW7
uniprot id: A0A8B7WTX4
uniprot id: A0A8B7WTZ7
uniprot id: A0A8B7WU05
uniprot id: A0A8B7WU12
uniprot id: A0A8B7WU19
uniprot id: A0A8B7WV92
uniprot id: A0A8B7WV98
uniprot id: A0A8B7WVA4
uniprot id: A0A8B7WVB1
names: Similarity
messages: Belongs to the N-CoR nuclear receptor corepressors family.

30608:NCBP3
gene id: 30608:NCBP3
uniprot id: A0A8B7WNE2
names: Similarity
messages: Belongs to the NCBP3 family.

30608:LOC105875022
gene id: 30608:LOC105875022
uniprot id: A0A8B7GU27
uniprot id: A0A8B7GU66
uniprot id: A0A8B7GU75
uniprot id: A0A8B7GU86
uniprot id: A0A8B7GUE6
uniprot id: A0A8B7GUH5
uniprot id: A0A8B7GVT3
uniprot id: A0A8B7GVU3
uniprot id: A0A8B7GW23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

30608:PLSCR3
gene id: 30608:PLSCR3
uniprot id: A0A8B7H6G2
uniprot id: A0A8B7H6G9
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

30608:LOC105869867
gene id: 30608:LOC105869867
uniprot id: A0A8B7G6P5
names: Subcellular Location Annotation
messages: Membrane

30608:CTTNBP2
gene id: 30608:CTTNBP2
uniprot id: Q2QL82
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CTTN/cortactin SH3 domain. Interacts with STRN, STRN4/zinedin and MOB4/phocein; this interaction may regulate dendritic spine distribution of STRN and STRN4 in hippocampal neurons. Activation of glutamate receptors weakens the interaction with STRN and STRN4.
messages: Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, thus controls dendritic spinogenesis and dendritic spine maintenance.
messages: cell cortex
messages: dendritic spine

30608:SEC61B
gene id: 30608:SEC61B
uniprot id: A0A8B7GNI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Necessary for protein translocation in the endoplasmic reticulum.

30608:CTBP1
gene id: 30608:CTBP1
uniprot id: A0A8B7HMG4
uniprot id: A0A8B7HMG5
uniprot id: A0A8B7HNX9
uniprot id: A0A8C5XS62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

30608:MEX3C
gene id: 30608:MEX3C
uniprot id: A0A8C5Y605
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:ASCC3
gene id: 30608:ASCC3
uniprot id: A0A8B7EI22
uniprot id: A0A8C5UVW3
names: Similarity
messages: Belongs to the helicase family.

30608:PSPN
gene id: 30608:PSPN
uniprot id: A0A8C5VUB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

30608:NELFCD
gene id: 30608:NELFCD
uniprot id: A0A8B7GRJ7
uniprot id: A0A8B7GRK2
uniprot id: A0A8B7GRK3
uniprot id: A0A8B7GRU2
uniprot id: A0A8B7GRW6
uniprot id: A0A8B7WQW0
uniprot id: A0A8C5VYZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NELF-D family.
messages: Nucleus

30608:USP16
gene id: 30608:USP16
uniprot id: A0A8B7GBG7
uniprot id: A0A8B7GBH1
uniprot id: A0A8B7GBH6
uniprot id: A0A8B7GBZ2
uniprot id: A0A8B7GCI0
uniprot id: A0A8C5Y6U1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. USP16 subfamily.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Homotetramer.
messages: Nucleus
messages: Phosphorylated at the onset of mitosis and dephosphorylated during the metaphase/anaphase transition. Phosphorylation by AURKB enhances the deubiquitinase activity.
messages: Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.
messages: The UBP-type zinc finger binds 3 zinc ions that form a pair of cross-braced ring fingers encapsulated within a third zinc finger in the primary structure. It recognizes the C-terminal tail of free ubiquitin.

30608:TLE2
gene id: 30608:TLE2
uniprot id: A0A8B7GNV8
uniprot id: A0A8B7GP60
uniprot id: A0A8B7GQB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

30608:LOC105876468
gene id: 30608:LOC105876468
uniprot id: A0A8B7GYN3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

30608:FGF4
gene id: 30608:FGF4
uniprot id: A0A8C5Y1R7
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

30608:NPEPPS
gene id: 30608:NPEPPS
uniprot id: A0A8C5W924
uniprot id: A0A8C5XSA1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

30608:YAF2
gene id: 30608:YAF2
uniprot id: A0A8B7F1N8
uniprot id: A0A8B7F1S3
uniprot id: A0A8B7F1Y9
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105881938
gene id: 30608:LOC105881938
uniprot id: A0A8B7HQE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CDX4
gene id: 30608:CDX4
uniprot id: A0A8B7FRF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

30608:LOC105883385
gene id: 30608:LOC105883385
uniprot id: A0A8B7HX36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105855726
gene id: 30608:LOC105855726
uniprot id: A0A8C5XGK3
names: Similarity
messages: Belongs to the NipSnap family.

30608:GINS1
gene id: 30608:GINS1
uniprot id: A0A8B7EZT2
uniprot id: A0A8B7F1I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Chromosome
messages: Component of the GINS complex which is a heterotetramer of GINS1, GINS2, GINS3 and GINS4. Forms a stable subcomplex with GINS4. GINS complex interacts with DNA primase in vitro. Component of the CMG helicase complex, a hexameric ring of related MCM2-7 subunits stabilized by CDC45 and the tetrameric GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.

30608:ZNF397
gene id: 30608:ZNF397
uniprot id: A0A8B7ER68
names: Subcellular Location Annotation
messages: Nucleus

30608:IPO7
gene id: 30608:IPO7
uniprot id: A0A8B7HQL2
uniprot id: A0A8B7HRD4
names: Subcellular Location Annotation
messages: Cytoplasm

30608:MAPK8IP2
gene id: 30608:MAPK8IP2
uniprot id: A0A8B7I2L3
uniprot id: A0A8B7I4M6
uniprot id: A0A8C5VBD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JIP scaffold family.
messages: Cytoplasm

30608:AVIL
gene id: 30608:AVIL
uniprot id: A0A8B7H7R9
uniprot id: A0A8B7H7S0
uniprot id: A0A8B7H7S5
uniprot id: A0A8B7H7S6
uniprot id: A0A8B7H7T2
uniprot id: A0A8B7HAB9
uniprot id: A0A8B7HAC4
uniprot id: A0A8B7X6G0
names: Similarity
messages: Belongs to the villin/gelsolin family.

30608:LOC105870343
gene id: 30608:LOC105870343
uniprot id: A0A8B7G7X3
names: Subcellular Location Annotation
messages: Mitochondrion

30608:NOX3
gene id: 30608:NOX3
uniprot id: A0A8B7FZL4
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105864532
gene id: 30608:LOC105864532
uniprot id: A0A8B7FHF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105874391
gene id: 30608:LOC105874391
uniprot id: A0A8B7GQY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:GART
gene id: 30608:GART
uniprot id: A0A8B7WYN7
names: Similarity
messages: In the C-terminal section; belongs to the GART family.
messages: In the N-terminal section; belongs to the GARS family.
messages: In the central section; belongs to the AIR synthase family.

30608:RDH10
gene id: 30608:RDH10
uniprot id: A0A8B7HUR8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:AK4
gene id: 30608:AK4
uniprot id: A0A8B7GIM7
uniprot id: A0A8B7GIX6
uniprot id: A0A8B7X901
uniprot id: A0A8B7XAM6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP/ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP/ATP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.
messages: Mitochondrion matrix
messages: Monomer.

30608:LSM14A
gene id: 30608:LSM14A
uniprot id: A0A8C6EGG1
uniprot id: A0A8C6EJ93
names: Similarity
messages: Belongs to the LSM14 family.

30608:LHX2
gene id: 30608:LHX2
uniprot id: A0A8B7GV21
names: Subcellular Location Annotation
messages: Nucleus

30608:TMEM126A
gene id: 30608:TMEM126A
uniprot id: A0A8C5UXY0
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105885804
gene id: 30608:LOC105885804
uniprot id: A0A8B7I9Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

30608:LOC105861335
gene id: 30608:LOC105861335
uniprot id: A0A8B7WVF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM43 family.
messages: Membrane

30608:HIRIP3
gene id: 30608:HIRIP3
uniprot id: A0A8B7GBF3
names: Subcellular Location Annotation
messages: Nucleus

30608:SH3BP5
gene id: 30608:SH3BP5
uniprot id: A0A8B7GIH1
uniprot id: A0A8B7GIQ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

30608:B3GALNT1
gene id: 30608:B3GALNT1
uniprot id: A0A8B7X358
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:LOC105883335
gene id: 30608:LOC105883335
uniprot id: A0A8B7HWY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105876159
gene id: 30608:LOC105876159
uniprot id: A0A8B7XC78
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:PPIH
gene id: 30608:PPIH
uniprot id: A0A8B7F7U0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

30608:ACTR6
gene id: 30608:ACTR6
uniprot id: A0A8B7I024
names: Similarity
messages: Belongs to the actin family.

30608:DCTN6
gene id: 30608:DCTN6
uniprot id: A0A8C6EE62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
messages: Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.
messages: cytoskeleton

30608:TPRG1L
gene id: 30608:TPRG1L
uniprot id: A0A8C5XJF3
names: Similarity
messages: Belongs to the TPRG1 family.

30608:ZNF75D
gene id: 30608:ZNF75D
uniprot id: A0A8B7WZE4
names: Subcellular Location Annotation
messages: Nucleus

30608:CHST3
gene id: 30608:CHST3
uniprot id: A0A8B7G6Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

30608:TRRAP
gene id: 30608:TRRAP
uniprot id: A0A8B7WPC4
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. TRA1 subfamily.

30608:NPM2
gene id: 30608:NPM2
uniprot id: A0A8B7EJI0
names: Similarity
messages: Belongs to the nucleoplasmin family.

30608:NMNAT3
gene id: 30608:NMNAT3
uniprot id: A0A8B7G654
uniprot id: A0A8B7G6W4
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

30608:FLI1
gene id: 30608:FLI1
uniprot id: A0A8B7GW82
uniprot id: A0A8B7GXX2
uniprot id: A0A8C5XU29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

30608:ATP6V1G2
gene id: 30608:ATP6V1G2
uniprot id: A0A8B7ENQ0
uniprot id: A0A8B7X4P1
uniprot id: D0VXS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

30608:DDX55
gene id: 30608:DDX55
uniprot id: A0A8B7WTN0
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

30608:HSD17B7
gene id: 30608:HSD17B7
uniprot id: A0A8C5UX99
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.

30608:HBS1L
gene id: 30608:HBS1L
uniprot id: A0A8B7EJM5
names: Subcellular Location Annotation
messages: Cytoplasm

30608:CHFR
gene id: 30608:CHFR
uniprot id: A0A8B7F5R6
uniprot id: A0A8B7WTK3
uniprot id: A0A8B7WTK9
uniprot id: A0A8B7WTS4
uniprot id: A0A8B7WTW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CHFR family.
messages: PML body

30608:ELOC
gene id: 30608:ELOC
uniprot id: A0A8B7E9K7
names: Similarity
messages: Belongs to the SKP1 family.

30608:IL2
gene id: 30608:IL2
uniprot id: A0A8C5VAS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-2 family.
messages: Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal roles in the immune response and tolerance. Binds to a receptor complex composed of either the high-affinity trimeric IL-2R (IL2RA/CD25, IL2RB/CD122 and IL2RG/CD132) or the low-affinity dimeric IL-2R (IL2RB and IL2RG). Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3. In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5. This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways. Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well. Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production. Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance. Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells.
messages: Secreted

30608:LOC105866439
gene id: 30608:LOC105866439
uniprot id: A0A8B7FR04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105873460
gene id: 30608:LOC105873460
uniprot id: A0A8B7GLR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Membrane
messages: Microsome membrane

30608:DOLPP1
gene id: 30608:DOLPP1
uniprot id: A0A8B7GVW8
uniprot id: A0A8B7GVX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dolichyldiphosphatase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.

30608:PKLR
gene id: 30608:PKLR
uniprot id: A0A8B7GK09
uniprot id: A0A8B7GK10
uniprot id: A0A8B7GKC1
names: Similarity
messages: Belongs to the pyruvate kinase family.

30608:OVCH1
gene id: 30608:OVCH1
uniprot id: A0A8B7WTR1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:RPL31
gene id: 30608:RPL31
uniprot id: A0A8B7EM37
uniprot id: A0A8C5XES3
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

30608:KCNH8
gene id: 30608:KCNH8
uniprot id: A0A8B7HM83
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

30608:SLC14A2
gene id: 30608:SLC14A2
uniprot id: A0A8B7I7N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

30608:COQ10B
gene id: 30608:COQ10B
uniprot id: A0A8B7H7C7
uniprot id: A0A8C5XE64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

30608:SERPING1
gene id: 30608:SERPING1
uniprot id: A0A8B7FB76
uniprot id: A0A8B7FB80
names: Similarity
messages: Belongs to the serpin family.

30608:NECAP1
gene id: 30608:NECAP1
uniprot id: A0A8B7G313
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

30608:ANXA6
gene id: 30608:ANXA6
uniprot id: A0A8C5UIR9
uniprot id: A0A8C5XNG2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
messages: Melanosome

30608:SLC16A5
gene id: 30608:SLC16A5
uniprot id: A0A8B7HBN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

30608:LOC105884169
gene id: 30608:LOC105884169
uniprot id: A0A8B7HYM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:GNAT3
gene id: 30608:GNAT3
uniprot id: A0A8B7HDE7
names: Similarity
messages: Belongs to the G-alpha family. G(i/o/t/z) subfamily.

30608:PSMD5
gene id: 30608:PSMD5
uniprot id: A0A8B7GUT9
uniprot id: A0A8C5XVD7
names: Similarity
messages: Belongs to the proteasome subunit S5B/HSM3 family.

30608:GSTM4
gene id: 30608:GSTM4
uniprot id: A0A8B7FFE9
uniprot id: A0A8B7FFK5
names: Similarity
names: Subunit
messages: Belongs to the GST superfamily. Mu family.
messages: Homodimer.

30608:ITGB7
gene id: 30608:ITGB7
uniprot id: A0A8B7G9D3
uniprot id: A0A8B7G9U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

30608:TAF10
gene id: 30608:TAF10
uniprot id: A0A8B7HV59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Nucleus

30608:GRM7
gene id: 30608:GRM7
uniprot id: A0A8B7G399
uniprot id: A0A8B7G3A4
uniprot id: A0A8B7G3A5
uniprot id: A0A8B7G3A6
uniprot id: A0A8B7G455
uniprot id: A0A8B7WWN5
uniprot id: A0A8B7WWZ8
uniprot id: A0A8B7WXF1
uniprot id: A0A8B7WYE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

30608:EIF3A
gene id: 30608:EIF3A
uniprot id: A0A8B7EIW6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3L and EIF3K. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with EIF4G1. Also interacts with KRT7 and PIWIL2.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.

30608:LOC105884681
gene id: 30608:LOC105884681
uniprot id: A0A8B7I0Y8
names: Similarity
messages: Belongs to the CAMK2N family.

30608:CORO1B
gene id: 30608:CORO1B
uniprot id: A0A8B7FVP0
names: Similarity
messages: Belongs to the WD repeat coronin family.

30608:RTN2
gene id: 30608:RTN2
uniprot id: A0A8B7G5C2
uniprot id: A0A8C6EIC9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:HCST
gene id: 30608:HCST
uniprot id: A0A8B7WUG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAP10 family.
messages: Membrane

30608:LOC105856398
gene id: 30608:LOC105856398
uniprot id: A0A8C5YC89
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

30608:EYA3
gene id: 30608:EYA3
uniprot id: A0A8B7FD13
uniprot id: A0A8C5XH64
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

30608:ZRANB1
gene id: 30608:ZRANB1
uniprot id: A0A8C5XVV4
names: Similarity
messages: Belongs to the peptidase C64 family.

30608:SCN4A
gene id: 30608:SCN4A
uniprot id: A0A8B7F5E1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

30608:ATP5L
gene id: 30608:ATP5L
uniprot id: A0A8B7H190
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion

30608:CNOT1
gene id: 30608:CNOT1
uniprot id: A0A8B7WSH4
uniprot id: A0A8B7WSJ7
uniprot id: A0A8B7WSN7
uniprot id: A0A8B7WTZ6
uniprot id: A0A8C5UZV5
uniprot id: A0A8C5XKN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT1 family.
messages: Nucleus

30608:CPT1B
gene id: 30608:CPT1B
uniprot id: A0A8B7I5K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

30608:DYRK2
gene id: 30608:DYRK2
uniprot id: A0A8B7HK80
uniprot id: A0A8B7HLF4
uniprot id: A0A8C5VFU5
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

30608:T
gene id: 30608:T
uniprot id: A0A8B7H713
uniprot id: A0A8B7H9I4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

30608:LOC105855949
gene id: 30608:LOC105855949
uniprot id: A0A8B7EGN8
names: Similarity
messages: Belongs to the MHC class I family.

30608:LOC105878269
gene id: 30608:LOC105878269
uniprot id: A0A8B7H8T2
uniprot id: A0A8B7X850
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Cell projection
messages: Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport.
messages: Perikaryon
messages: Transport is mediated via a series of conformation changes, switching between a conformation where the substrate-binding cavity is accessible from the outside, and a another conformation where it is accessible from the cytoplasm.

30608:LOC105864594
gene id: 30608:LOC105864594
uniprot id: A0A8B7X1B5
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105867756
gene id: 30608:LOC105867756
uniprot id: A0A8B7FW32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105867931
gene id: 30608:LOC105867931
uniprot id: A0A8B7FXP3
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:TNRC6A
gene id: 30608:TNRC6A
uniprot id: A0A8B7HEY4
uniprot id: A0A8B7HF07
uniprot id: A0A8B7WNW5
uniprot id: A0A8B7WNX6
uniprot id: A0A8B7WQ69
uniprot id: A0A8C5XKF3
uniprot id: A0A8C6EFH9
names: Similarity
messages: Belongs to the GW182 family.

30608:EWSR1
gene id: 30608:EWSR1
uniprot id: A0A8B7GA60
uniprot id: A0A8B7GAG1
uniprot id: A0A8B7GAX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

30608:SAR1B
gene id: 30608:SAR1B
uniprot id: A0A8B7WRT6
names: Similarity
messages: Belongs to the small GTPase superfamily. SAR1 family.

30608:RPLP1
gene id: 30608:RPLP1
uniprot id: A0A8C5VY59
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

30608:MORF4L2
gene id: 30608:MORF4L2
uniprot id: A0A8B7I0Q5
names: Subcellular Location Annotation
messages: Nucleus

30608:VAMP4
gene id: 30608:VAMP4
uniprot id: A0A8B7GDQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

30608:GPM6B
gene id: 30608:GPM6B
uniprot id: A0A8B7HQV9
uniprot id: A0A8B7HQW0
uniprot id: A0A8B7HQX0
uniprot id: A0A8B7HSQ5
uniprot id: A0A8B7HT86
uniprot id: A0A8B7HT90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

30608:CCT4
gene id: 30608:CCT4
uniprot id: A0A8B7X2N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

30608:GLI3
gene id: 30608:GLI3
uniprot id: A0A8B7ENA8
uniprot id: A0A8B7ENB2
uniprot id: A0A8B7EQH3
uniprot id: A0A8C6EGZ5
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

30608:SELE
gene id: 30608:SELE
uniprot id: A0A8B7HNP7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selectin/LECAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:ITGB1
gene id: 30608:ITGB1
uniprot id: A0A8B7ELT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

30608:DRC7
gene id: 30608:DRC7
uniprot id: A0A8B7EVT8
uniprot id: A0A8C5W0Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC7 family.
messages: cilium axoneme
messages: flagellum
messages: flagellum axoneme

30608:UBAC2
gene id: 30608:UBAC2
uniprot id: A0A8C5XEI0
names: Subcellular Location Annotation
messages: Membrane

30608:TMEM131
gene id: 30608:TMEM131
uniprot id: A0A8B7HWB2
uniprot id: A0A8B7HWC3
uniprot id: A0A8B7HYE7
names: Similarity
messages: Belongs to the TMEM131 family.

30608:TLL1
gene id: 30608:TLL1
uniprot id: A0A8B7WKQ6
uniprot id: A0A8B7WKT3
uniprot id: A0A8B7WKV1
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:C3AR1
gene id: 30608:C3AR1
uniprot id: A0A8B7G254
uniprot id: A0A8B7G255
uniprot id: A0A8B7G3J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Interacts with VGF-derived peptide TLQP-21.
messages: Membrane
messages: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

30608:LOC109729687
gene id: 30608:LOC109729687
uniprot id: A0A8B7WQJ0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

30608:LOC105870047
gene id: 30608:LOC105870047
uniprot id: A0A8B7G7G4
uniprot id: A0A8B7X7M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

30608:CALCRL
gene id: 30608:CALCRL
uniprot id: A0A8C5VY22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3.
messages: Membrane
messages: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

30608:LOC105861980
gene id: 30608:LOC105861980
uniprot id: A0A8C5Y4J8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

30608:FAM134B
gene id: 30608:FAM134B
uniprot id: A0A8C5UWP9
uniprot id: A0A8C5VD20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RETREG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:EPHX1
gene id: 30608:EPHX1
uniprot id: A0A8C5XHX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

30608:TAS1R3
gene id: 30608:TAS1R3
uniprot id: A0A8B7H5Z4
uniprot id: A0A8B7H609
uniprot id: A0A8C5Y0L6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:NSUN5
gene id: 30608:NSUN5
uniprot id: A0A8B7ERC6
uniprot id: A0A8B7ERE2
uniprot id: A0A8C6EDS6
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:SLC26A10
gene id: 30608:SLC26A10
uniprot id: A0A8B7X5S6
uniprot id: A0A8B7X5S7
uniprot id: A0A8B7X7T0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:CAPN13
gene id: 30608:CAPN13
uniprot id: A0A8B7HZU9
names: Similarity
messages: Belongs to the peptidase C2 family.

30608:KRT84
gene id: 30608:KRT84
uniprot id: A0A8B7GCR3
names: Similarity
messages: Belongs to the intermediate filament family.

30608:CSF3
gene id: 30608:CSF3
uniprot id: A0A8B7WML6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
messages: Secreted

30608:PCYT1B
gene id: 30608:PCYT1B
uniprot id: A0A8B7HQC4
uniprot id: A0A8B7HSQ7
uniprot id: A0A8C5VWA0
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

30608:SOX12
gene id: 30608:SOX12
uniprot id: A0A8C5XQN7
names: Subcellular Location Annotation
messages: Nucleus

30608:IFIH1
gene id: 30608:IFIH1
uniprot id: A0A8B7G1H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

30608:RAD23B
gene id: 30608:RAD23B
uniprot id: A0A8B7EDH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Nucleus

30608:OSGEPL1
gene id: 30608:OSGEPL1
uniprot id: A0A8B7H9J9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Mitochondrion
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

30608:MMP1
gene id: 30608:MMP1
uniprot id: A0A8B7GRT0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

30608:LAPTM5
gene id: 30608:LAPTM5
uniprot id: A0A8B7FUB0
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

30608:STARD13
gene id: 30608:STARD13
uniprot id: A0A8B7XDW7
uniprot id: A0A8B7XG70
uniprot id: A0A8C5Y9A1
names: Subcellular Location Annotation
messages: Cytoplasm

30608:BNIP3
gene id: 30608:BNIP3
uniprot id: A0A8B7WN91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

30608:B4GALT5
gene id: 30608:B4GALT5
uniprot id: A0A8C5VNC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

30608:AP3S1
gene id: 30608:AP3S1
uniprot id: A0A8B7G9J1
uniprot id: A0A8B7G9J3
uniprot id: A0A8B7GA61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

30608:ACER2
gene id: 30608:ACER2
uniprot id: A0A8B7GQ65
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:SLC5A4
gene id: 30608:SLC5A4
uniprot id: A0A8B7GAT1
uniprot id: A0A8B7GAZ6
uniprot id: A0A8B7GB01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

30608:LOC105859217
gene id: 30608:LOC105859217
uniprot id: A0A8B7EV14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:UNC45B
gene id: 30608:UNC45B
uniprot id: A0A8C5XID5
names: Subcellular Location Annotation
messages: perinuclear region

30608:LOC109729955
gene id: 30608:LOC109729955
uniprot id: A0A8B7WUR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative pheromone receptor.

30608:LGMN
gene id: 30608:LGMN
uniprot id: A0A8B7EJW5
names: Similarity
messages: Belongs to the peptidase C13 family.

30608:SCN1B
gene id: 30608:SCN1B
uniprot id: A0A8B7WTW4
uniprot id: A0A8B7WU26
names: Subcellular Location Annotation
messages: Membrane

30608:TMC6
gene id: 30608:TMC6
uniprot id: A0A8B7FRS4
uniprot id: A0A8B7FRT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

30608:LOC105862037
gene id: 30608:LOC105862037
uniprot id: A0A8B7F6P3
uniprot id: A0A8C5VC70
names: Similarity
messages: Belongs to the NXPE family.

30608:LOC109731106
gene id: 30608:LOC109731106
uniprot id: A0A8B7X9X6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

30608:LOC109729189
gene id: 30608:LOC109729189
uniprot id: A0A8B7HTP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

30608:LOC105861326
gene id: 30608:LOC105861326
uniprot id: A0A8B7F2Q1
names: Subcellular Location Annotation
messages: Membrane

30608:IP6K3
gene id: 30608:IP6K3
uniprot id: A0A8B7F304
uniprot id: A0A8B7F3Z5
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

30608:CRH
gene id: 30608:CRH
uniprot id: A0A8B7EEH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

30608:DOK6
gene id: 30608:DOK6
uniprot id: A0A8B7HEK2
uniprot id: A0A8B7HEM5
uniprot id: A0A8B7HEZ2
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

30608:YEATS2
gene id: 30608:YEATS2
uniprot id: A0A8B7EDC7
uniprot id: A0A8B7EDD4
uniprot id: A0A8B7EE01
uniprot id: A0A8B7X2Y2
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105861300
gene id: 30608:LOC105861300
uniprot id: A0A8B7F2M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CLK4
gene id: 30608:CLK4
uniprot id: A0A8B7HXD5
uniprot id: A0A8B7HXE6
uniprot id: A0A8B7HZG7
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:ORAI1
gene id: 30608:ORAI1
uniprot id: A0A8B7HL48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

30608:UBL4A
gene id: 30608:UBL4A
uniprot id: A0A8B7FWB5
names: Subcellular Location Annotation
messages: cytosol

30608:CHRDL2
gene id: 30608:CHRDL2
uniprot id: A0A8B7EYS2
uniprot id: A0A8B7F0X2
uniprot id: A0A8C5VBA8
names: Subcellular Location Annotation
messages: Secreted

30608:LOC105878373
gene id: 30608:LOC105878373
uniprot id: A0A8B7H976
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

30608:UBXN1
gene id: 30608:UBXN1
uniprot id: A0A8B7HAD6
uniprot id: A0A8B7HAD7
uniprot id: A0A8B7HD47
names: Subcellular Location Annotation
messages: Cytoplasm

30608:SH3BP5L
gene id: 30608:SH3BP5L
uniprot id: A0A8B7FMV1
uniprot id: A0A8B7FMX6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

30608:LOC105862144
gene id: 30608:LOC105862144
uniprot id: A0A8B7F746
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

30608:TJP1
gene id: 30608:TJP1
uniprot id: A0A8B7GBU7
uniprot id: A0A8B7GCE5
uniprot id: A0A8B7XA51
uniprot id: A0A8B7XA53
uniprot id: A0A8B7XAW8
uniprot id: A0A8B7XBV1
uniprot id: A0A8B7XCA3
uniprot id: A0A8B7XCA8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: tight junction

30608:LOC105858567
gene id: 30608:LOC105858567
uniprot id: A0A8B7X791
uniprot id: A0A8B7X8J1
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

30608:LOC105880970
gene id: 30608:LOC105880970
uniprot id: A0A8B7WXZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Cytoplasm
messages: May be involved in spermatogenesis.
messages: Nucleus

30608:LOC105874637
gene id: 30608:LOC105874637
uniprot id: A0A8C5W7L8
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. GNA1 subfamily.
messages: Homodimer.

30608:LOC105858693
gene id: 30608:LOC105858693
uniprot id: A0A8B7EQW5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:LIMS1
gene id: 30608:LIMS1
uniprot id: A0A8B7EEZ9
uniprot id: A0A8B7EFJ7
uniprot id: A0A8B7EFK2
uniprot id: A0A8B7EFQ9
uniprot id: A0A8B7EHJ3
uniprot id: A0A8C5Y8Q0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors.
messages: Cell membrane
messages: Part of the heterotrimeric IPP complex composed of integrin-linked kinase (ILK), LIMS1 or LIMS2, and PARVA.
messages: focal adhesion

30608:ARSE
gene id: 30608:ARSE
uniprot id: A0A8B7WYS6
names: Similarity
messages: Belongs to the sulfatase family.

30608:MINDY4
gene id: 30608:MINDY4
uniprot id: A0A8B7EAK4
uniprot id: A0A8B7EAK9
uniprot id: A0A8B7EAN6
uniprot id: A0A8B7EAW7
uniprot id: A0A8B7EB92
uniprot id: A0A8B7EB97
uniprot id: A0A8B7EDB2
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

30608:SLC12A9
gene id: 30608:SLC12A9
uniprot id: A0A8B7FZG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

30608:DNAJB14
gene id: 30608:DNAJB14
uniprot id: A0A8B7EH21
uniprot id: A0A8B7WY51
uniprot id: A0A8B7WYK0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:LIMD1
gene id: 30608:LIMD1
uniprot id: A0A8B7WSS6
uniprot id: A0A8C5YGR0
names: Similarity
messages: Belongs to the zyxin/ajuba family.

30608:WDR48
gene id: 30608:WDR48
uniprot id: A0A8B7ET07
uniprot id: A0A8B7WZZ7
uniprot id: A0A8B7X141
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR48 family.
messages: Late endosome

30608:LOC105879342
gene id: 30608:LOC105879342
uniprot id: A0A8B7HDE0
names: Similarity
messages: Belongs to the CD36 family.

30608:PIGU
gene id: 30608:PIGU
uniprot id: A0A8B7WPZ5
uniprot id: A0A8C5VEX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:IL15RA
gene id: 30608:IL15RA
uniprot id: A0A8B7ENY1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:CA4
gene id: 30608:CA4
uniprot id: A0A8B7H8M4
uniprot id: A0A8C5V2Q6
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

30608:ARF1
gene id: 30608:ARF1
uniprot id: A0A8B7HB94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

30608:LDLRAD2
gene id: 30608:LDLRAD2
uniprot id: A0A8B7GML1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:XRCC3
gene id: 30608:XRCC3
uniprot id: A0A8B7F3S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Cytoplasm
messages: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions.
messages: Nucleus

30608:IRF2BP2
gene id: 30608:IRF2BP2
uniprot id: A0A8B7EGN6
uniprot id: A0A8B7EH37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

30608:PQLC1
gene id: 30608:PQLC1
uniprot id: A0A8B7WR78
names: Subcellular Location Annotation
messages: Membrane

30608:C15H10orf90
gene id: 30608:C15H10orf90
uniprot id: A0A8B7HHW1
uniprot id: A0A8B7WM83
names: Subcellular Location Annotation
messages: centrosome

30608:ZDHHC23
gene id: 30608:ZDHHC23
uniprot id: A0A8B7HXS2
uniprot id: A0A8B7HZU2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

30608:SLC24A1
gene id: 30608:SLC24A1
uniprot id: A0A8B7FXS6
uniprot id: A0A8B7FYK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

30608:SEMA4B
gene id: 30608:SEMA4B
uniprot id: A0A8B7G8L6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105877497
gene id: 30608:LOC105877497
uniprot id: A0A8B7H547
uniprot id: A0A8B7H580
uniprot id: A0A8B7H7F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRH/QCR6 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

30608:LOC105858879
gene id: 30608:LOC105858879
uniprot id: A0A8B7ETL8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:PSMC3
gene id: 30608:PSMC3
uniprot id: A0A8B7I124
names: Similarity
messages: Belongs to the AAA ATPase family.

30608:RPL22
gene id: 30608:RPL22
uniprot id: A0A8B7I7R2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

30608:DTX3
gene id: 30608:DTX3
uniprot id: A0A8B7H7P5
uniprot id: A0A8B7H7Q7
uniprot id: A0A8B7HA98
uniprot id: A0A8C5URW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

30608:DST
gene id: 30608:DST
uniprot id: A0A8B7HGK6
uniprot id: A0A8B7HJ85
uniprot id: A0A8B7X6L0
names: Subcellular Location Annotation
messages: cytoskeleton

30608:GALE
gene id: 30608:GALE
uniprot id: A0A8B7FDG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.
messages: Homodimer.

30608:SLC25A17
gene id: 30608:SLC25A17
uniprot id: A0A8B7EQ87
uniprot id: A0A8B7EQC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:RDH5
gene id: 30608:RDH5
uniprot id: A0A8B7FIM0
uniprot id: A0A8B7X5X5
uniprot id: A0A8C5YCU5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:CD44
gene id: 30608:CD44
uniprot id: A0A8B7FPN8
uniprot id: A0A8B7FPV5
uniprot id: A0A8B7FPW0
uniprot id: A0A8B7FPW5
uniprot id: A0A8B7FPW6
uniprot id: A0A8B7FPX1
uniprot id: A0A8B7FQ75
uniprot id: A0A8B7FQ80
uniprot id: A0A8B7FQX4
uniprot id: A0A8C5YAH9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: microvillus

30608:DOCK7
gene id: 30608:DOCK7
uniprot id: A0A8B7GI52
uniprot id: A0A8B7GI54
uniprot id: A0A8B7GI58
uniprot id: A0A8B7GI59
uniprot id: A0A8B7GI65
uniprot id: A0A8B7GIH8
uniprot id: A0A8B7GII5
uniprot id: A0A8B7GIS7
uniprot id: A0A8B7GIT3
uniprot id: A0A8B7GIT9
uniprot id: A0A8B7GJ41
uniprot id: A0A8B7GJ49
uniprot id: A0A8B7GJ55
uniprot id: A0A8B7XAS1
names: Similarity
messages: Belongs to the DOCK family.

30608:LOC105873287
gene id: 30608:LOC105873287
uniprot id: A0A8B7GKN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Odorant receptor.

30608:MGST2
gene id: 30608:MGST2
uniprot id: A0A8B7GGY9
uniprot id: A0A8C5Y6X5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:GTF2F2
gene id: 30608:GTF2F2
uniprot id: A0A8C5XP23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.

30608:ABLIM1
gene id: 30608:ABLIM1
uniprot id: A0A8B7GWW3
uniprot id: A0A8B7GWX2
uniprot id: A0A8B7GWX3
uniprot id: A0A8B7GWX7
uniprot id: A0A8B7GWY0
uniprot id: A0A8B7GWY5
uniprot id: A0A8B7GX11
uniprot id: A0A8B7GX16
uniprot id: A0A8B7GX33
uniprot id: A0A8B7GX48
uniprot id: A0A8B7GX57
uniprot id: A0A8B7GX67
uniprot id: A0A8B7GX85
uniprot id: A0A8B7GXA9
uniprot id: A0A8B7GYQ4
uniprot id: A0A8B7GYT1
uniprot id: A0A8B7GYV6
uniprot id: A0A8B7GYX4
uniprot id: A0A8B7GZ02
uniprot id: A0A8B7WLZ4
uniprot id: A0A8B7WMY1
names: Subcellular Location Annotation
messages: Cytoplasm

30608:NUDCD1
gene id: 30608:NUDCD1
uniprot id: A0A8B7HUK9
uniprot id: A0A8C5VZX5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:SLC25A41
gene id: 30608:SLC25A41
uniprot id: A0A8B7G4N5
uniprot id: A0A8B7WVQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:CC2D1A
gene id: 30608:CC2D1A
uniprot id: A0A8B7WVP4
uniprot id: A0A8B7WVZ6
uniprot id: A0A8B7WWB4
uniprot id: A0A8B7WXC8
names: Similarity
messages: Belongs to the CC2D1 family.

30608:PMCH
gene id: 30608:PMCH
uniprot id: A0A8B7GX28
names: Similarity
messages: Belongs to the melanin-concentrating hormone family.

30608:TYRO3
gene id: 30608:TYRO3
uniprot id: A0A8B7GGP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

30608:RB1
gene id: 30608:RB1
uniprot id: A0A8B7XDR9
uniprot id: A0A8B7XDS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

30608:VPS13D
gene id: 30608:VPS13D
uniprot id: A0A8B7WPM5
names: Similarity
messages: Belongs to the VPS13 family.

30608:BCAP29
gene id: 30608:BCAP29
uniprot id: A0A8B7F1B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a role in the export of secreted proteins in the ER.

30608:LOC105867248
gene id: 30608:LOC105867248
uniprot id: A0A8B7FTN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

30608:EIF4G2
gene id: 30608:EIF4G2
uniprot id: A0A8B7FQQ6
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

30608:PPM1L
gene id: 30608:PPM1L
uniprot id: A0A8C5YFY2
names: Similarity
messages: Belongs to the PP2C family.

30608:SBF1
gene id: 30608:SBF1
uniprot id: A0A8B7I2P2
uniprot id: A0A8B7I2P6
uniprot id: A0A8B7I5P2
uniprot id: A0A8C5V4M2
uniprot id: A0A8C5W572
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

30608:VGLL1
gene id: 30608:VGLL1
uniprot id: A0A8B7FRZ1
uniprot id: A0A8B7FSL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

30608:ADAMTS6
gene id: 30608:ADAMTS6
uniprot id: A0A8B7HP45
uniprot id: A0A8B7HP46
uniprot id: A0A8B7HRI5
uniprot id: A0A8B7XCP8
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:LOC105864486
gene id: 30608:LOC105864486
uniprot id: A0A8B7FH94
names: Subcellular Location Annotation
messages: Membrane

30608:CACNA2D4
gene id: 30608:CACNA2D4
uniprot id: A0A8B7F4T5
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

30608:ARL5B
gene id: 30608:ARL5B
uniprot id: A0A8B7F8A4
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

30608:FRAT2
gene id: 30608:FRAT2
uniprot id: A0A8B7GKD0
names: Similarity
messages: Belongs to the GSK-3-binding protein family.

30608:LOC105881469
gene id: 30608:LOC105881469
uniprot id: A0A8B7HPH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Nucleus

30608:ITFG1
gene id: 30608:ITFG1
uniprot id: A0A8B7GZX4
names: Similarity
messages: Belongs to the TIP family.

30608:FZD9
gene id: 30608:FZD9
uniprot id: A0A8B7ERC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Membrane

30608:PLA2G1B
gene id: 30608:PLA2G1B
uniprot id: A0A8B7FTQ5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

30608:LOC105875436
gene id: 30608:LOC105875436
uniprot id: A0A8B7GWP4
uniprot id: A0A8C5VP65
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:PIGS
gene id: 30608:PIGS
uniprot id: A0A8C5VAQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:SIDT1
gene id: 30608:SIDT1
uniprot id: A0A8B7HXP7
uniprot id: A0A8B7HXQ2
uniprot id: A0A8B7HXQ6
uniprot id: A0A8B7HXR0
uniprot id: A0A8B7HXR5
uniprot id: A0A8B7HXR6
uniprot id: A0A8B7HXS1
uniprot id: A0A8B7HZS6
uniprot id: A0A8B7HZT0
uniprot id: A0A8B7I0C3
uniprot id: A0A8B7X5M6
uniprot id: A0A8B7X5N3
uniprot id: A0A8B7X7N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SID1 family.
messages: Membrane

30608:GJD2
gene id: 30608:GJD2
uniprot id: A0A8C5V963
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

30608:APTX
gene id: 30608:APTX
uniprot id: A0A8B7GQX4
uniprot id: A0A8B7GQY3
uniprot id: A0A8B7GR64
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus
messages: nucleoplasm

30608:CD247
gene id: 30608:CD247
uniprot id: A0A8B7HNK4
uniprot id: A0A8B7HNK7
uniprot id: A0A8B7HNK9
uniprot id: A0A8B7HQ80
uniprot id: A0A8B7HR25
uniprot id: A0A8B7X010
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD3Z/FCER1G family.
messages: Cell membrane
messages: Membrane

30608:IL16
gene id: 30608:IL16
uniprot id: A0A8B7FG58
uniprot id: A0A8B7FG63
uniprot id: A0A8B7FG87
uniprot id: A0A8B7FGB4
uniprot id: A0A8B7FHA1
uniprot id: A0A8B7XA74
uniprot id: A0A8B7XA75
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homotetramer.
messages: Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.
messages: Nucleus
messages: Secreted

30608:LOC105857596
gene id: 30608:LOC105857596
uniprot id: A0A8B7EL24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:LOC105885159
gene id: 30608:LOC105885159
uniprot id: A0A8B7I6G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Odorant receptor.

30608:STAC
gene id: 30608:STAC
uniprot id: A0A8C5YGT1
names: Subcellular Location Annotation
messages: sarcolemma

30608:MEF2A
gene id: 30608:MEF2A
uniprot id: A0A8B7GBQ2
uniprot id: A0A8B7GC87
uniprot id: A0A8B7GC93
uniprot id: A0A8B7GCA6
uniprot id: A0A8B7GCR0
uniprot id: A0A8C5XN58
names: Subcellular Location Annotation
messages: Nucleus

30608:PLK3
gene id: 30608:PLK3
uniprot id: A0A8B7H752
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

30608:CHST4
gene id: 30608:CHST4
uniprot id: A0A8B7ESH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

30608:LOC109731180
gene id: 30608:LOC109731180
uniprot id: A0A8B7XDE0
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

30608:DGKH
gene id: 30608:DGKH
uniprot id: A0A8B7XER7
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

30608:ECHDC1
gene id: 30608:ECHDC1
uniprot id: A0A8B7H8G8
uniprot id: A0A8B7H8H8
uniprot id: A0A8B7HB39
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

30608:ATP6V0A2
gene id: 30608:ATP6V0A2
uniprot id: A0A8C5URU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

30608:SNAPC3
gene id: 30608:SNAPC3
uniprot id: A0A8B7GPP6
uniprot id: A0A8B7XAX6
uniprot id: A0A8B7XCL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNAPC3/SRD2 family.
messages: Nucleus
messages: Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts with SNAPC1.
messages: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.

30608:DCK
gene id: 30608:DCK
uniprot id: A0A8B7HVU2
names: Similarity
messages: Belongs to the DCK/DGK family.

30608:WWOX
gene id: 30608:WWOX
uniprot id: A0A8B7F9R1
uniprot id: A0A8B7F9R9
uniprot id: A0A8B7F9S2
uniprot id: A0A8B7F9V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Golgi apparatus
messages: Lysosome
messages: Mitochondrion

30608:PGLYRP3
gene id: 30608:PGLYRP3
uniprot id: A0A8B7I742
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

30608:SLCO4A1
gene id: 30608:SLCO4A1
uniprot id: A0A8B7GXN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

30608:CPQ
gene id: 30608:CPQ
uniprot id: A0A8B7G5C9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes the hydrolysis of dipeptides with unsubstituted terminals into amino acids. May play a role in the liberation of thyroxine hormone from its thyroglobulin (Tg) precursor.
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. The monomeric form is inactive while the homodimer is active.
messages: Lysosome

30608:SUPT5H
gene id: 30608:SUPT5H
uniprot id: A0A8B7H1Q8
uniprot id: A0A8B7H3S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT5 family.
messages: Nucleus

30608:CADM4
gene id: 30608:CADM4
uniprot id: A0A8B7G3K1
uniprot id: A0A8B7WW98
names: Similarity
messages: Belongs to the nectin family.

30608:CPB1
gene id: 30608:CPB1
uniprot id: A0A8B7HL50
names: Similarity
messages: Belongs to the peptidase M14 family.

30608:LOC109730588
gene id: 30608:LOC109730588
uniprot id: A0A8B7X241
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

30608:SNRPE
gene id: 30608:SNRPE
uniprot id: A0A8B7FY26
uniprot id: A0A8B7FY35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

30608:CDK17
gene id: 30608:CDK17
uniprot id: A0A8C5XH24
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:PAFAH1B1
gene id: 30608:PAFAH1B1
uniprot id: A0A8B7EMX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Can self-associate. Interacts with DCX, dynein, dynactin, IQGAP1, KATNB1, NDE1, NDEL1, NUDC and RSN. Interacts with DISC1, and this interaction is enhanced by NDEL1. Interacts with DAB1 when DAB1 is phosphorylated in response to RELN/reelin signaling. Component of cytosolic PAF-AH IB, which is composed of PAFAH1B1 (alpha), PAFAH1B2 (beta) and PAFAH1B3 (gamma) subunits. Trimer formation is not essential for the catalytic activity of the enzyme which is contributed solely by the PAFAH1B2 (beta) and PAFAH1B3 (gamma) subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus membrane
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Neuronal migration involves a process called nucleokinesis, whereby migrating cells extend an anterior process into which the nucleus subsequently translocates. During nucleokinesis dynein at the nuclear surface may translocate the nucleus towards the centrosome by exerting force on centrosomal microtubules. Also required for proper activation of Rho GTPases and actin polymerization at the leading edge of locomoting cerebellar neurons and postmigratory hippocampal neurons in response to calcium influx triggered via NMDA receptors. May also play a role in other forms of cell locomotion including the migration of fibroblasts during wound healing. Non-catalytic subunit of an acetylhydrolase complex which inactivates platelet-activating factor (PAF) by removing the acetyl group at the SN-2 position.
messages: centrosome
messages: cytoskeleton
messages: spindle

30608:LOC105883692
gene id: 30608:LOC105883692
uniprot id: A0A8B7HYL8
uniprot id: A0A8B7HYZ4
names: Similarity
messages: Belongs to the peroxisomal targeting signal receptor family.

30608:FN3KRP
gene id: 30608:FN3KRP
uniprot id: A0A8B7H843
uniprot id: A0A8B7H864
names: Similarity
messages: Belongs to the fructosamine kinase family.

30608:MUC6
gene id: 30608:MUC6
uniprot id: A0A8B7X5H2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:NAA35
gene id: 30608:NAA35
uniprot id: A0A8B7HX51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. Involved in regulation of apoptosis and proliferation of smooth muscle cells.
messages: Belongs to the MAK10 family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.
messages: Cytoplasm

30608:TLR4
gene id: 30608:TLR4
uniprot id: A0A8B7GMC5
uniprot id: A0A8B7GMD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

30608:LOC105857919
gene id: 30608:LOC105857919
uniprot id: A0A8B7EML5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

30608:F7
gene id: 30608:F7
uniprot id: A0A8B7XFR7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:ADAM12
gene id: 30608:ADAM12
uniprot id: A0A8B7HHV3
uniprot id: A0A8B7HKF8
uniprot id: A0A8C5Y2I4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:FAM207A
gene id: 30608:FAM207A
uniprot id: A0A8B7HEQ6
uniprot id: A0A8C5Y4E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLX9 family.
messages: nucleolus

30608:C1D
gene id: 30608:C1D
uniprot id: A0A8B7FBV0
uniprot id: A0A8B7FBV4
uniprot id: A0A8B7FC05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the C1D family.
messages: Cytoplasm
messages: Monomer and homodimer.
messages: Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.
messages: nucleolus

30608:ABCC2
gene id: 30608:ABCC2
uniprot id: A0A8B7GLM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

30608:ABCB10
gene id: 30608:ABCB10
uniprot id: A0A8B7GC73
names: Subcellular Location Annotation
messages: Membrane

30608:LPAR4
gene id: 30608:LPAR4
uniprot id: A0A8B7FPQ3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:HSPA14
gene id: 30608:HSPA14
uniprot id: A0A8B7EIG6
uniprot id: A0A8C5VV39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Component of ribosome-associated complex (RAC), a heterodimer composed of Hsp70/DnaK-type chaperone HSPA14 and Hsp40/DnaJ-type chaperone DNAJC2.
messages: Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity.
messages: cytosol

30608:MAL2
gene id: 30608:MAL2
uniprot id: A0A8C5Y6D5
names: Subcellular Location Annotation
messages: Membrane

30608:PANX2
gene id: 30608:PANX2
uniprot id: A0A8B7I5S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

30608:FERMT2
gene id: 30608:FERMT2
uniprot id: A0A8B7FVT6
uniprot id: A0A8B7FVT9
uniprot id: A0A8B7FW01
uniprot id: A0A8B7FWS5
uniprot id: A0A8B7FWT0
uniprot id: A0A8B7FWT4
names: Similarity
messages: Belongs to the kindlin family.

30608:FAM3B
gene id: 30608:FAM3B
uniprot id: A0A8B7WY43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

30608:LOC105881712
gene id: 30608:LOC105881712
uniprot id: A0A8B7HMT6
uniprot id: A0A8B7HMY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

30608:GALNT3
gene id: 30608:GALNT3
uniprot id: A0A8B7G478
uniprot id: A0A8B7G4S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

30608:ADAMTS5
gene id: 30608:ADAMTS5
uniprot id: A0A8C5UZI9
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:OSBPL5
gene id: 30608:OSBPL5
uniprot id: A0A8C5VB49
names: Similarity
messages: Belongs to the OSBP family.

30608:SSR2
gene id: 30608:SSR2
uniprot id: A0A8B7GK93
uniprot id: A0A8C5XM17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-beta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

30608:TXLNG
gene id: 30608:TXLNG
uniprot id: A0A8B7HQP6
names: Similarity
messages: Belongs to the taxilin family.

30608:APOA4
gene id: 30608:APOA4
uniprot id: A0A8C5XBB5
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

30608:BANF1
gene id: 30608:BANF1
uniprot id: A0A8B7HA90
names: Subcellular Location Annotation
messages: Nucleus

30608:STAT2
gene id: 30608:STAT2
uniprot id: A0A8B7FL32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

30608:CCNJ
gene id: 30608:CCNJ
uniprot id: A0A8B7GI48
uniprot id: A0A8B7GIJ2
uniprot id: A0A8C5VBJ3
names: Similarity
messages: Belongs to the cyclin family.

30608:LLPH
gene id: 30608:LLPH
uniprot id: A0A8B7X5V4
names: Similarity
messages: Belongs to the learning-associated protein family.

30608:EML6
gene id: 30608:EML6
uniprot id: A0A8B7H9B1
uniprot id: A0A8B7H9B9
uniprot id: A0A8B7H9C6
uniprot id: A0A8B7HC33
names: Function
names: Similarity
messages: Belongs to the WD repeat EMAP family.
messages: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.

30608:METTL26
gene id: 30608:METTL26
uniprot id: A0A8B7EFJ0
uniprot id: A0A8B7EG19
uniprot id: A0A8C5YEE7
names: Similarity
messages: Belongs to the UPF0585 family.

30608:TAF7L
gene id: 30608:TAF7L
uniprot id: A0A8B7GIZ9
uniprot id: A0A8B7GJ02
uniprot id: A0A8B7GJC6
uniprot id: A0A8B7GJM6
uniprot id: A0A8B7GK27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

30608:TCEA3
gene id: 30608:TCEA3
uniprot id: A0A8C5USD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

30608:TM4SF4
gene id: 30608:TM4SF4
uniprot id: A0A8C5YIX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

30608:SPCS3
gene id: 30608:SPCS3
uniprot id: A0A8C5XXR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS3 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:SMARCD3
gene id: 30608:SMARCD3
uniprot id: A0A8B7HUA3
uniprot id: A0A8B7HUB1
uniprot id: A0A8B7HUC1
uniprot id: A0A8B7HWE6
names: Similarity
messages: Belongs to the SMARCD family.

30608:PPP1R1C
gene id: 30608:PPP1R1C
uniprot id: A0A8C5VKE8
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

30608:SGMS1
gene id: 30608:SGMS1
uniprot id: A0A8B7G7U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

30608:LOC105855016
gene id: 30608:LOC105855016
uniprot id: A0A8C5XVW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KXD1 family.
messages: Lysosome membrane

30608:TCF7
gene id: 30608:TCF7
uniprot id: A0A8B7WR09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

30608:SEC23B
gene id: 30608:SEC23B
uniprot id: A0A8B7WQM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

30608:CD74
gene id: 30608:CD74
uniprot id: A0A8C5YFU8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:APLN
gene id: 30608:APLN
uniprot id: A0A8B7WZK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apelin family.
messages: extracellular space

30608:MRPL27
gene id: 30608:MRPL27
uniprot id: A0A8B7I372
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

30608:NAT10
gene id: 30608:NAT10
uniprot id: A0A8B7EM17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with THUMPD1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

30608:TMEM170B
gene id: 30608:TMEM170B
uniprot id: A0A8B7FK91
uniprot id: A0A8B7FKD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

30608:OLFML2B
gene id: 30608:OLFML2B
uniprot id: A0A8B7GM02
uniprot id: A0A8B7GMB9
uniprot id: A0A8B7GMJ5
uniprot id: A0A8C5UHV1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:NHSL1
gene id: 30608:NHSL1
uniprot id: A0A8B7F6R2
uniprot id: A0A8B7F6S9
uniprot id: A0A8B7F6T4
uniprot id: A0A8C5XUS2
uniprot id: A0A8C5YBX6
names: Similarity
messages: Belongs to the NHS family.

30608:RIOK3
gene id: 30608:RIOK3
uniprot id: A0A8C5VJQ9
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
messages: Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses.

30608:EMC9
gene id: 30608:EMC9
uniprot id: A0A8B7FR83
names: Similarity
messages: Belongs to the EMC8/EMC9 family.

30608:ABCA7
gene id: 30608:ABCA7
uniprot id: A0A8B7F093
uniprot id: A0A8B7F1Z4
uniprot id: A0A8B7F2J1
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105873524
gene id: 30608:LOC105873524
uniprot id: A0A8B7GLR9
names: Similarity
messages: Belongs to the UPF0547 family.

30608:PRKCZ
gene id: 30608:PRKCZ
uniprot id: A0A8B7WNI6
uniprot id: A0A8B7WNJ4
uniprot id: A0A8B7WNJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

30608:GOT2
gene id: 30608:GOT2
uniprot id: A0A8B7EXR0
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

30608:CNIH2
gene id: 30608:CNIH2
uniprot id: A0A8B7FUM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

30608:LOC105871465
gene id: 30608:LOC105871465
uniprot id: A0A8B7GDB3
names: Subcellular Location Annotation
messages: Membrane

30608:NANOS3
gene id: 30608:NANOS3
uniprot id: A0A8B7I4Q0
names: Similarity
messages: Belongs to the nanos family.

30608:LOC105884131
gene id: 30608:LOC105884131
uniprot id: A0A8B7I172
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MRPS30
gene id: 30608:MRPS30
uniprot id: A0A8C5UYB1
names: Subcellular Location Annotation
messages: Mitochondrion

30608:PML
gene id: 30608:PML
uniprot id: A0A8B7F759
uniprot id: A0A8B7F762
uniprot id: A0A8B7F763
uniprot id: A0A8B7F764
uniprot id: A0A8B7F768
uniprot id: A0A8B7F795
uniprot id: A0A8B7F799
uniprot id: A0A8B7F7D6
uniprot id: A0A8B7X2D5
names: Subcellular Location Annotation
messages: Cytoplasm

30608:LOC105864699
gene id: 30608:LOC105864699
uniprot id: W0UUW9
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

30608:PLCB2
gene id: 30608:PLCB2
uniprot id: A0A8B7GGF3
uniprot id: A0A8B7GGG4
uniprot id: A0A8B7GH61
uniprot id: A0A8B7X1H4
names: Cofactor
names: Function
messages: Binds 1 Ca(2+) ion per subunit.
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

30608:OAT
gene id: 30608:OAT
uniprot id: A0A8B7HIM9
uniprot id: A0A8B7HKC5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

30608:ARRB1
gene id: 30608:ARRB1
uniprot id: A0A8B7EYK5
uniprot id: A0A8B7EYK8
uniprot id: A0A8B7EYK9
uniprot id: A0A8B7F0D2
uniprot id: A0A8B7F0P7
names: Similarity
messages: Belongs to the arrestin family.

30608:P3H2
gene id: 30608:P3H2
uniprot id: A0A8B7F0P6
names: Similarity
messages: Belongs to the leprecan family.

30608:TNFRSF21
gene id: 30608:TNFRSF21
uniprot id: A0A8B7EXZ5
uniprot id: A0A8C5V9B2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:MRAP2
gene id: 30608:MRAP2
uniprot id: A0A8B7GNE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRAP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:CCDC181
gene id: 30608:CCDC181
uniprot id: A0A8B7HNP3
uniprot id: A0A8B7HNP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC181 family.
messages: Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids.
messages: cytoskeleton
messages: flagellum

30608:CENPBD1
gene id: 30608:CENPBD1
uniprot id: A0A8B7WSU4
names: Subcellular Location Annotation
messages: Nucleus

30608:PSIP1
gene id: 30608:PSIP1
uniprot id: A0A8B7GR86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HDGF family.
messages: Nucleus

30608:YTHDF1
gene id: 30608:YTHDF1
uniprot id: A0A8B7GXU1
uniprot id: A0A8B7GZJ5
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

30608:FAM162A
gene id: 30608:FAM162A
uniprot id: A0A8C5YFT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0389 family.
messages: Membrane

30608:TMEM121
gene id: 30608:TMEM121
uniprot id: A0A8B7F3Y6
names: Similarity
messages: Belongs to the TMEM121 family.

30608:LOC105862982
gene id: 30608:LOC105862982
uniprot id: A0A8B7FB68
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

30608:TOR3A
gene id: 30608:TOR3A
uniprot id: A0A8B7GYR9
names: Similarity
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.

30608:AMER1
gene id: 30608:AMER1
uniprot id: A0A8B7FBD2
names: Similarity
messages: Belongs to the Amer family.

30608:CD9
gene id: 30608:CD9
uniprot id: A0A8C5UVK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Cell membrane
messages: Membrane
messages: extracellular exosome

30608:NKAP
gene id: 30608:NKAP
uniprot id: A0A8C5V0G9
names: Similarity
messages: Belongs to the NKAP family.

30608:CNOT6
gene id: 30608:CNOT6
uniprot id: A0A8B7WQU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

30608:ALKBH3
gene id: 30608:ALKBH3
uniprot id: A0A8B7I514
uniprot id: A0A8B7I569
uniprot id: A0A8B7I739
uniprot id: A0A8B7X308
names: Similarity
messages: Belongs to the alkB family.

30608:MTX1
gene id: 30608:MTX1
uniprot id: A0A8B7GKE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

30608:LOC105870240
gene id: 30608:LOC105870240
uniprot id: A0A8B7G783
names: Similarity
messages: Belongs to the CCDC90 family.

30608:LOC105858713
gene id: 30608:LOC105858713
uniprot id: A0A8B7ET20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105857636
gene id: 30608:LOC105857636
uniprot id: A0A8B7ELH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

30608:EIF1B
gene id: 30608:EIF1B
uniprot id: A0A8B7GRC9
names: Similarity
messages: Belongs to the SUI1 family.

30608:PSMB6
gene id: 30608:PSMB6
uniprot id: A0A8B7HFJ8
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105865681
gene id: 30608:LOC105865681
uniprot id: A0A8B7FNQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Odorant receptor.

30608:LOC105873223
gene id: 30608:LOC105873223
uniprot id: A0A8B7GKR4
uniprot id: A0A8B7GL26
uniprot id: A0A8B7GLK7
uniprot id: A0A8B7XBW5
uniprot id: A0A8C5W6L7
names: Similarity
messages: Belongs to the Luc7 family.

30608:CA9
gene id: 30608:CA9
uniprot id: A0A8B7GS41
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

30608:SDHAF2
gene id: 30608:SDHAF2
uniprot id: A0A8B7HAK9
uniprot id: A0A8B7HAL3
uniprot id: A0A8B7HDC5
uniprot id: A0A8B7X4B6
uniprot id: A0A8C5XWD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with SDHA within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.

30608:SPSB1
gene id: 30608:SPSB1
uniprot id: A0A8B7IAQ3
names: Similarity
messages: Belongs to the SPSB family.

30608:MED13L
gene id: 30608:MED13L
uniprot id: A0A8B7FS87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

30608:EPHA1
gene id: 30608:EPHA1
uniprot id: A0A8B7GKQ0
uniprot id: A0A8B7GLB9
names: Subcellular Location Annotation
messages: Membrane

30608:NDUFAF4
gene id: 30608:NDUFAF4
uniprot id: A0A8B7GPD8
names: Similarity
names: Subunit
messages: Belongs to the NDUFAF4 family.
messages: Binds calmodulin. Interacts with NDUFAF3.

30608:PPP2R3C
gene id: 30608:PPP2R3C
uniprot id: A0A8B7ECM5
uniprot id: A0A8B7EEV5
names: Subcellular Location Annotation
messages: Nucleus

30608:PRPF19
gene id: 30608:PRPF19
uniprot id: A0A8B7HAQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Lipid droplet
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.
messages: nucleoplasm

30608:TRMT112
gene id: 30608:TRMT112
uniprot id: A0A8C5VCE5
names: Similarity
messages: Belongs to the TRM112 family.

30608:LOC105865725
gene id: 30608:LOC105865725
uniprot id: A0A8B7FMW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PCNX3
gene id: 30608:PCNX3
uniprot id: A0A8B7HA04
uniprot id: A0A8B7HA10
uniprot id: A0A8B7HA11
uniprot id: A0A8B7HA13
uniprot id: A0A8B7HA14
uniprot id: A0A8B7HCS5
uniprot id: A0A8B7X354
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

30608:RNASEH2A
gene id: 30608:RNASEH2A
uniprot id: A0A8B7WW50
uniprot id: A0A8B7WW52
uniprot id: A0A8B7WWU7
uniprot id: A0A8B7WXU6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

30608:RPS11
gene id: 30608:RPS11
uniprot id: A0A8C5VT95
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

30608:ALG9
gene id: 30608:ALG9
uniprot id: A0A8B7FA79
uniprot id: A0A8B7FA80
uniprot id: A0A8B7FA84
uniprot id: A0A8B7FA85
uniprot id: A0A8B7FA87
uniprot id: A0A8B7FA92
uniprot id: A0A8B7FAE1
uniprot id: A0A8B7FAE6
uniprot id: A0A8B7FAV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:SLC39A5
gene id: 30608:SLC39A5
uniprot id: A0A8B7FJZ2
uniprot id: A0A8B7FLF9
names: Subcellular Location Annotation
messages: Membrane

30608:SHANK2
gene id: 30608:SHANK2
uniprot id: A0A8B7FUI5
uniprot id: A0A8B7FUI6
uniprot id: A0A8B7FUJ0
uniprot id: A0A8B7FUJ4
uniprot id: A0A8B7FUJ5
uniprot id: A0A8B7FUJ8
uniprot id: A0A8B7FUN1
uniprot id: A0A8B7FVD7
uniprot id: A0A8B7FVE3
uniprot id: A0A8B7FVE8
uniprot id: A0A8B7FVF4
uniprot id: A0A8B7FVJ0
uniprot id: A0A8B7FVJ9
uniprot id: A0A8B7X3G2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Postsynaptic density

30608:MYO15A
gene id: 30608:MYO15A
uniprot id: A0A8B7F6E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: cytoskeleton

30608:UMPS
gene id: 30608:UMPS
uniprot id: A0A8C5YIU0
names: Similarity
messages: In the C-terminal section; belongs to the OMP decarboxylase family.
messages: In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

30608:LOC105865633
gene id: 30608:LOC105865633
uniprot id: A0A8B7FM88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Odorant receptor.

30608:SLC25A32
gene id: 30608:SLC25A32
uniprot id: A0A8B7HPM5
uniprot id: A0A8B7HRC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:LOC105859377
gene id: 30608:LOC105859377
uniprot id: A0A8B7EVN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

30608:LOC105874071
gene id: 30608:LOC105874071
uniprot id: A0A8C5VU36
names: Similarity
messages: Belongs to the CD225/Dispanin family.

30608:LOC105866532
gene id: 30608:LOC105866532
uniprot id: A0A8B7FQW0
uniprot id: A0A8B7FR05
uniprot id: A0A8B7FRF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane