293826:AMET RS22265
gene id: 293826:AMET_RS22265
uniprot id: A6TWG0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

293826:AMET RS02605
gene id: 293826:AMET_RS02605
uniprot id: A6TKM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

293826:AMET RS11335
gene id: 293826:AMET_RS11335
uniprot id: A6TQI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

293826:AMET RS12570
gene id: 293826:AMET_RS12570
uniprot id: A6TR78
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

293826:AMET RS15595
gene id: 293826:AMET_RS15595
uniprot id: A6TSZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

293826:AMET RS03295
gene id: 293826:AMET_RS03295
uniprot id: A6TL18
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS16605
gene id: 293826:AMET_RS16605
uniprot id: A6TTJ0
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

293826:AMET RS06085
gene id: 293826:AMET_RS06085
uniprot id: A6TMM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

293826:AMET RS10975
gene id: 293826:AMET_RS10975
uniprot id: A6TQB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

293826:AMET RS18170
gene id: 293826:AMET_RS18170
uniprot id: A6TUE9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

293826:AMET RS01110
gene id: 293826:AMET_RS01110
uniprot id: A6TJS7
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS05310
gene id: 293826:AMET_RS05310
uniprot id: A6TM70
names: Similarity
messages: Belongs to the EamA transporter family.

293826:AMET RS17575
gene id: 293826:AMET_RS17575
uniprot id: A6TU35
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

293826:AMET RS02630
gene id: 293826:AMET_RS02630
uniprot id: A6TKN2
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS10925
gene id: 293826:AMET_RS10925
uniprot id: A6TQA2
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

293826:AMET RS08295
gene id: 293826:AMET_RS08295
uniprot id: A6TNT6
names: Similarity
messages: Belongs to the disproportionating enzyme family.

293826:AMET RS18570
gene id: 293826:AMET_RS18570
uniprot id: A6TUM8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

293826:AMET RS00840
gene id: 293826:AMET_RS00840
uniprot id: A6TJM3
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

293826:AMET RS17830
gene id: 293826:AMET_RS17830
uniprot id: A6TU82
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

293826:AMET RS02685
gene id: 293826:AMET_RS02685
uniprot id: A6TKP3
names: Similarity
messages: Belongs to the YciI family.

293826:AMET RS23275
gene id: 293826:AMET_RS23275
uniprot id: A6TX10
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS24405
gene id: 293826:AMET_RS24405
uniprot id: A6TSA8
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS08175
gene id: 293826:AMET_RS08175
uniprot id: A6TNR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

293826:AMET RS08655
gene id: 293826:AMET_RS08655
uniprot id: A6TNZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS05385
gene id: 293826:AMET_RS05385
uniprot id: A6TM85
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

293826:AMET RS01625
gene id: 293826:AMET_RS01625
uniprot id: A6TK28
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS22615
gene id: 293826:AMET_RS22615
uniprot id: A6TWM8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

293826:AMET RS10820
gene id: 293826:AMET_RS10820
uniprot id: A6TQ82
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

293826:AMET RS22205
gene id: 293826:AMET_RS22205
uniprot id: A6TWE8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS17955
gene id: 293826:AMET_RS17955
uniprot id: A6TUA7
names: Similarity
messages: Belongs to the manganese catalase family.

293826:AMET RS17350
gene id: 293826:AMET_RS17350
uniprot id: A6TTZ0
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS05645
gene id: 293826:AMET_RS05645
uniprot id: A6TMD8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

293826:AMET RS03955
gene id: 293826:AMET_RS03955
uniprot id: A6TLF7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

293826:AMET RS02970
gene id: 293826:AMET_RS02970
uniprot id: A6TKV0
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

293826:AMET RS23715
gene id: 293826:AMET_RS23715
uniprot id: A6TX95
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS20230
gene id: 293826:AMET_RS20230
uniprot id: A6TVI4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

293826:AMET RS06350
gene id: 293826:AMET_RS06350
uniprot id: A6TMS2
names: Similarity
messages: Belongs to the GerABKA family.

293826:AMET RS10260
gene id: 293826:AMET_RS10260
uniprot id: A6TPW8
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS22695
gene id: 293826:AMET_RS22695
uniprot id: A6TWP4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

293826:AMET RS22305
gene id: 293826:AMET_RS22305
uniprot id: A6TWG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

293826:AMET RS18425
gene id: 293826:AMET_RS18425
uniprot id: A6TUJ9
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

293826:AMET RS05790
gene id: 293826:AMET_RS05790
uniprot id: A6TMG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

293826:AMET RS16740
gene id: 293826:AMET_RS16740
uniprot id: A6TTL7
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

293826:AMET RS15840
gene id: 293826:AMET_RS15840
uniprot id: A6TT35
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

293826:AMET RS22330
gene id: 293826:AMET_RS22330
uniprot id: A6TWH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

293826:AMET RS23935
gene id: 293826:AMET_RS23935
uniprot id: A6TXD9
names: Similarity
messages: Belongs to the ParB family.

293826:AMET RS15530
gene id: 293826:AMET_RS15530
uniprot id: A6TSX8
names: Similarity
messages: Belongs to the AOR/FOR family.

293826:AMET RS23095
gene id: 293826:AMET_RS23095
uniprot id: A6TWX5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

293826:AMET RS19970
gene id: 293826:AMET_RS19970
uniprot id: A6TVD3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

293826:AMET RS12140
gene id: 293826:AMET_RS12140
uniprot id: A6TQZ4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

293826:AMET RS05495
gene id: 293826:AMET_RS05495
uniprot id: A6TMA9
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

293826:AMET RS17310
gene id: 293826:AMET_RS17310
uniprot id: A6TTY1
names: Similarity
messages: Belongs to the P(II) protein family.

293826:AMET RS06160
gene id: 293826:AMET_RS06160
uniprot id: A6TMN7
names: Similarity
messages: Belongs to the ThiD family.

293826:AMET RS08450
gene id: 293826:AMET_RS08450
uniprot id: A6TNW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

293826:AMET RS13455
gene id: 293826:AMET_RS13455
uniprot id: A6TRR1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

293826:AMET RS21655
gene id: 293826:AMET_RS21655
uniprot id: A6TW36
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

293826:AMET RS23885
gene id: 293826:AMET_RS23885
uniprot id: A6TXC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

293826:AMET RS04935
gene id: 293826:AMET_RS04935
uniprot id: A6TLZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

293826:AMET RS13530
gene id: 293826:AMET_RS13530
uniprot id: A6TRS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

293826:AMET RS11315
gene id: 293826:AMET_RS11315
uniprot id: A6TQH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

293826:AMET RS11605
gene id: 293826:AMET_RS11605
uniprot id: A6TQN4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

293826:AMET RS11285
gene id: 293826:AMET_RS11285
uniprot id: A6TQH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

293826:AMET RS02675
gene id: 293826:AMET_RS02675
uniprot id: A6TKP1
names: Similarity
messages: Belongs to the UPF0145 family.

293826:AMET RS20545
gene id: 293826:AMET_RS20545
uniprot id: A6TVQ0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

293826:AMET RS13545
gene id: 293826:AMET_RS13545
uniprot id: A6TRS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

293826:AMET RS03260
gene id: 293826:AMET_RS03260
uniprot id: A6TL11
names: Similarity
messages: Belongs to the peptidase C40 family.

293826:AMET RS20615
gene id: 293826:AMET_RS20615
uniprot id: A6TVR2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

293826:AMET RS13115
gene id: 293826:AMET_RS13115
uniprot id: A6TRJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

293826:AMET RS24255
gene id: 293826:AMET_RS24255
uniprot id: A6TNT1
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS00200
gene id: 293826:AMET_RS00200
uniprot id: A6TJA8
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

293826:AMET RS13490
gene id: 293826:AMET_RS13490
uniprot id: A6TRR6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS03415
gene id: 293826:AMET_RS03415
uniprot id: A6TL42
names: Similarity
messages: Belongs to the CdaR family.

293826:AMET RS20210
gene id: 293826:AMET_RS20210
uniprot id: A6TVI0
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS11690
gene id: 293826:AMET_RS11690
uniprot id: A6TQQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

293826:AMET RS08250
gene id: 293826:AMET_RS08250
uniprot id: A6TNS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

293826:AMET RS21160
gene id: 293826:AMET_RS21160
uniprot id: A6TW16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

293826:AMET RS04125
gene id: 293826:AMET_RS04125
uniprot id: A6TLJ2
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

293826:AMET RS15180
gene id: 293826:AMET_RS15180
uniprot id: A6TSQ7
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

293826:AMET RS16750
gene id: 293826:AMET_RS16750
uniprot id: A6TTL9
names: Subcellular Location Annotation
messages: Cytoplasm

293826:AMET RS05300
gene id: 293826:AMET_RS05300
uniprot id: A6TM68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

293826:AMET RS14785
gene id: 293826:AMET_RS14785
uniprot id: A6TSH9
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

293826:AMET RS14150
gene id: 293826:AMET_RS14150
uniprot id: A6TS52
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

293826:AMET RS18315
gene id: 293826:AMET_RS18315
uniprot id: A6TUH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

293826:AMET RS22390
gene id: 293826:AMET_RS22390
uniprot id: A6TWI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

293826:AMET RS20165
gene id: 293826:AMET_RS20165
uniprot id: A6TVH1
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

293826:AMET RS00550
gene id: 293826:AMET_RS00550
uniprot id: A6TJG9
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

293826:AMET RS16765
gene id: 293826:AMET_RS16765
uniprot id: A6TTM2
names: Similarity
messages: Belongs to the class-I fumarase family.

293826:AMET RS06805
gene id: 293826:AMET_RS06805
uniprot id: A6TN10
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS13790
gene id: 293826:AMET_RS13790
uniprot id: A6TRX4
names: Similarity
messages: Belongs to the YicC/YloC family.

293826:AMET RS06445
gene id: 293826:AMET_RS06445
uniprot id: A6TMU0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS19170
gene id: 293826:AMET_RS19170
uniprot id: A6TUY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

293826:AMET RS24150
gene id: 293826:AMET_RS24150
uniprot id: A6TLU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

293826:AMET RS03235
gene id: 293826:AMET_RS03235
uniprot id: A6TL06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

293826:AMET RS04610
gene id: 293826:AMET_RS04610
uniprot id: A6TLT7
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

293826:AMET RS15260
gene id: 293826:AMET_RS15260
uniprot id: A6TSS5
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

293826:AMET RS00405
gene id: 293826:AMET_RS00405
uniprot id: A6TJE0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

293826:AMET RS14310
gene id: 293826:AMET_RS14310
uniprot id: A6TS86
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

293826:AMET RS11045
gene id: 293826:AMET_RS11045
uniprot id: A6TQC7
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

293826:AMET RS09090
gene id: 293826:AMET_RS09090
uniprot id: A6TP80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Catalyzes arsenite efflux from the cell.
messages: Cell membrane

293826:AMET RS24350
gene id: 293826:AMET_RS24350
uniprot id: A6TQK0
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

293826:AMET RS17040
gene id: 293826:AMET_RS17040
uniprot id: A6TTS7
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS03980
gene id: 293826:AMET_RS03980
uniprot id: A6TLG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

293826:AMET RS09785
gene id: 293826:AMET_RS09785
uniprot id: A6TPM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

293826:AMET RS01555
gene id: 293826:AMET_RS01555
uniprot id: A6TK16
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

293826:AMET RS23970
gene id: 293826:AMET_RS23970
uniprot id: A6TXE6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

293826:AMET RS20245
gene id: 293826:AMET_RS20245
uniprot id: A6TVI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

293826:AMET RS05280
gene id: 293826:AMET_RS05280
uniprot id: A6TM64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

293826:AMET RS00515
gene id: 293826:AMET_RS00515
uniprot id: A6TJG2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

293826:AMET RS16625
gene id: 293826:AMET_RS16625
uniprot id: A6TTJ4
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS14965
gene id: 293826:AMET_RS14965
uniprot id: A6TSL4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

293826:AMET RS01895
gene id: 293826:AMET_RS01895
uniprot id: A6TK82
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

293826:AMET RS03070
gene id: 293826:AMET_RS03070
uniprot id: A6TKX0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

293826:AMET RS00370
gene id: 293826:AMET_RS00370
uniprot id: A6TJD3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

293826:AMET RS09130
gene id: 293826:AMET_RS09130
uniprot id: A6TP90
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

293826:AMET RS02390
gene id: 293826:AMET_RS02390
uniprot id: A6TKI4
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

293826:AMET RS18545
gene id: 293826:AMET_RS18545
uniprot id: A6TUM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

293826:AMET RS04315
gene id: 293826:AMET_RS04315
uniprot id: A6TLM8
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

293826:AMET RS18625
gene id: 293826:AMET_RS18625
uniprot id: A6TUN8
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS04420
gene id: 293826:AMET_RS04420
uniprot id: A6TLQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS07135
gene id: 293826:AMET_RS07135
uniprot id: A6TN78
names: Similarity
messages: Belongs to the universal stress protein A family.

293826:AMET RS08830
gene id: 293826:AMET_RS08830
uniprot id: A6TP24
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS10195
gene id: 293826:AMET_RS10195
uniprot id: A6TPV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS03080
gene id: 293826:AMET_RS03080
uniprot id: A6TKX2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS21105
gene id: 293826:AMET_RS21105
uniprot id: A6TW05
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

293826:AMET RS17735
gene id: 293826:AMET_RS17735
uniprot id: A6TU64
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

293826:AMET RS02915
gene id: 293826:AMET_RS02915
uniprot id: A6TKT8
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

293826:AMET RS18670
gene id: 293826:AMET_RS18670
uniprot id: A6TUP7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

293826:AMET RS23805
gene id: 293826:AMET_RS23805
uniprot id: A6TXB3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

293826:AMET RS14160
gene id: 293826:AMET_RS14160
uniprot id: A6TS54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

293826:AMET RS23955
gene id: 293826:AMET_RS23955
uniprot id: A6TXE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

293826:AMET RS15545
gene id: 293826:AMET_RS15545
uniprot id: A6TSY1
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS07670
gene id: 293826:AMET_RS07670
uniprot id: A6TNH0
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS10900
gene id: 293826:AMET_RS10900
uniprot id: A6TQ97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

293826:AMET RS17420
gene id: 293826:AMET_RS17420
uniprot id: A6TU04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

293826:AMET RS10895
gene id: 293826:AMET_RS10895
uniprot id: A6TQ96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

293826:AMET RS10765
gene id: 293826:AMET_RS10765
uniprot id: A6TQ71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

293826:AMET RS23655
gene id: 293826:AMET_RS23655
uniprot id: A6TX84
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

293826:AMET RS20940
gene id: 293826:AMET_RS20940
uniprot id: A6TVX5
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS01145
gene id: 293826:AMET_RS01145
uniprot id: A6TJT4
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

293826:AMET RS13695
gene id: 293826:AMET_RS13695
uniprot id: A6TRV6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

293826:AMET RS11290
gene id: 293826:AMET_RS11290
uniprot id: A6TQH4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

293826:AMET RS15585
gene id: 293826:AMET_RS15585
uniprot id: A6TSY9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

293826:AMET RS04925
gene id: 293826:AMET_RS04925
uniprot id: A6TLZ5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

293826:AMET RS04700
gene id: 293826:AMET_RS04700
uniprot id: A6TLV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

293826:AMET RS01530
gene id: 293826:AMET_RS01530
uniprot id: A6TK11
names: Similarity
messages: Belongs to the MotB family.

293826:AMET RS04310
gene id: 293826:AMET_RS04310
uniprot id: A6TLM7
names: Similarity
messages: Belongs to the GerABKA family.

293826:AMET RS22440
gene id: 293826:AMET_RS22440
uniprot id: A6TWJ5
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

293826:AMET RS16310
gene id: 293826:AMET_RS16310
uniprot id: A6TTC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS13335
gene id: 293826:AMET_RS13335
uniprot id: A6TRN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

293826:AMET RS18745
gene id: 293826:AMET_RS18745
uniprot id: A6TUR2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

293826:AMET RS00090
gene id: 293826:AMET_RS00090
uniprot id: A6TJ91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

293826:AMET RS11425
gene id: 293826:AMET_RS11425
uniprot id: A6TQK1
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS00810
gene id: 293826:AMET_RS00810
uniprot id: A6TJM0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

293826:AMET RS22245
gene id: 293826:AMET_RS22245
uniprot id: A6TWF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

293826:AMET RS02895
gene id: 293826:AMET_RS02895
uniprot id: A6TKT4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

293826:AMET RS13770
gene id: 293826:AMET_RS13770
uniprot id: A6TRX0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS20460
gene id: 293826:AMET_RS20460
uniprot id: A6TVN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

293826:AMET RS15625
gene id: 293826:AMET_RS15625
uniprot id: A6TSZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

293826:AMET RS10485
gene id: 293826:AMET_RS10485
uniprot id: A6TQ15
names: Similarity
messages: Belongs to the PemK/MazF family.

293826:AMET RS20535
gene id: 293826:AMET_RS20535
uniprot id: A6TVP8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

293826:AMET RS21700
gene id: 293826:AMET_RS21700
uniprot id: A6TW45
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane

293826:AMET RS10915
gene id: 293826:AMET_RS10915
uniprot id: A6TQA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

293826:AMET RS16720
gene id: 293826:AMET_RS16720
uniprot id: A6TTL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

293826:AMET RS09975
gene id: 293826:AMET_RS09975
uniprot id: A6TPR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

293826:AMET RS14505
gene id: 293826:AMET_RS14505
uniprot id: A6TSC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

293826:AMET RS25880
gene id: 293826:AMET_RS25880
uniprot id: A6TT45
names: Subcellular Location Annotation
messages: Cytoplasm

293826:AMET RS22580
gene id: 293826:AMET_RS22580
uniprot id: A6TWM4
names: Similarity
messages: Belongs to the class II ribonucleoside-triphosphate reductase family.

293826:AMET RS08345
gene id: 293826:AMET_RS08345
uniprot id: A6TNU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

293826:AMET RS22255
gene id: 293826:AMET_RS22255
uniprot id: A6TWF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

293826:AMET RS23130
gene id: 293826:AMET_RS23130
uniprot id: A6TWY2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

293826:AMET RS10670
gene id: 293826:AMET_RS10670
uniprot id: A6TQ51
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

293826:AMET RS26105
gene id: 293826:AMET_RS26105
uniprot id: A6TJC5
names: Similarity
messages: Belongs to the Ahb/Nir family.

293826:AMET RS16665
gene id: 293826:AMET_RS16665
uniprot id: A6TTK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

293826:AMET RS08000
gene id: 293826:AMET_RS08000
uniprot id: A6TNN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

293826:AMET RS02890
gene id: 293826:AMET_RS02890
uniprot id: A6TKT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

293826:AMET RS15765
gene id: 293826:AMET_RS15765
uniprot id: A6TT21
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

293826:AMET RS03180
gene id: 293826:AMET_RS03180
uniprot id: A6TKZ4
names: Similarity
messages: Belongs to the UPF0749 family.

293826:AMET RS16130
gene id: 293826:AMET_RS16130
uniprot id: A6TTA0
names: Similarity
messages: Belongs to the manganese catalase family.

293826:AMET RS10475
gene id: 293826:AMET_RS10475
uniprot id: A6TQ13
names: Similarity
messages: Belongs to the peptidase S8 family.

293826:AMET RS11025
gene id: 293826:AMET_RS11025
uniprot id: A6TQC3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

293826:AMET RS10050
gene id: 293826:AMET_RS10050
uniprot id: A6TPS9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

293826:AMET RS24145
gene id: 293826:AMET_RS24145
uniprot id: A6TLU0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS16365
gene id: 293826:AMET_RS16365
uniprot id: A6TTE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS03970
gene id: 293826:AMET_RS03970
uniprot id: A6TLG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

293826:AMET RS12505
gene id: 293826:AMET_RS12505
uniprot id: A6TR66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

293826:AMET RS05295
gene id: 293826:AMET_RS05295
uniprot id: A6TM67
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

293826:AMET RS23535
gene id: 293826:AMET_RS23535
uniprot id: A6TX60
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

293826:AMET RS16770
gene id: 293826:AMET_RS16770
uniprot id: A6TTM3
names: Similarity
messages: Belongs to the class-I fumarase family.

293826:AMET RS15030
gene id: 293826:AMET_RS15030
uniprot id: A6TSM7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

293826:AMET RS11350
gene id: 293826:AMET_RS11350
uniprot id: A6TQI6
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

293826:AMET RS16285
gene id: 293826:AMET_RS16285
uniprot id: A6TTC4
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS01525
gene id: 293826:AMET_RS01525
uniprot id: A6TK10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

293826:AMET RS03060
gene id: 293826:AMET_RS03060
uniprot id: A6TKW8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

293826:AMET RS20845
gene id: 293826:AMET_RS20845
uniprot id: A6TVV6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

293826:AMET RS14675
gene id: 293826:AMET_RS14675
uniprot id: A6TSF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

293826:AMET RS18585
gene id: 293826:AMET_RS18585
uniprot id: A6TUN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

293826:AMET RS06685
gene id: 293826:AMET_RS06685
uniprot id: A6TMY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

293826:AMET RS12480
gene id: 293826:AMET_RS12480
uniprot id: A6TR61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

293826:AMET RS20745
gene id: 293826:AMET_RS20745
uniprot id: A6TVT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

293826:AMET RS18610
gene id: 293826:AMET_RS18610
uniprot id: A6TUN5
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

293826:AMET RS08300
gene id: 293826:AMET_RS08300
uniprot id: A6TNT7
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

293826:AMET RS00085
gene id: 293826:AMET_RS00085
uniprot id: A6TJ90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

293826:AMET RS22395
gene id: 293826:AMET_RS22395
uniprot id: A6TWI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

293826:AMET RS23725
gene id: 293826:AMET_RS23725
uniprot id: A6TX99
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS00115
gene id: 293826:AMET_RS00115
uniprot id: A6TJ93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

293826:AMET RS00765
gene id: 293826:AMET_RS00765
uniprot id: A6TJL1
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS15275
gene id: 293826:AMET_RS15275
uniprot id: A6TSS8
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

293826:AMET RS17800
gene id: 293826:AMET_RS17800
uniprot id: A6TU77
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

293826:AMET RS16170
gene id: 293826:AMET_RS16170
uniprot id: A6TTA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS20100
gene id: 293826:AMET_RS20100
uniprot id: A6TVF9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

293826:AMET RS02920
gene id: 293826:AMET_RS02920
uniprot id: A6TKT9
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS16745
gene id: 293826:AMET_RS16745
uniprot id: A6TTL8
names: Similarity
messages: Belongs to the CitG/MdcB family.

293826:AMET RS13130
gene id: 293826:AMET_RS13130
uniprot id: A6TRJ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

293826:AMET RS25390
gene id: 293826:AMET_RS25390
uniprot id: A6TSH0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

293826:AMET RS14200
gene id: 293826:AMET_RS14200
uniprot id: A6TS62
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS13415
gene id: 293826:AMET_RS13415
uniprot id: A6TRQ3
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

293826:AMET RS10760
gene id: 293826:AMET_RS10760
uniprot id: A6TQ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

293826:AMET RS18410
gene id: 293826:AMET_RS18410
uniprot id: A6TUJ6
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

293826:AMET RS22450
gene id: 293826:AMET_RS22450
uniprot id: A6TWJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

293826:AMET RS17590
gene id: 293826:AMET_RS17590
uniprot id: A6TU38
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS10105
gene id: 293826:AMET_RS10105
uniprot id: A6TPT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS23770
gene id: 293826:AMET_RS23770
uniprot id: A6TXA8
names: Similarity
messages: Belongs to the peptidase S8 family.

293826:AMET RS12555
gene id: 293826:AMET_RS12555
uniprot id: A6TR75
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

293826:AMET RS20410
gene id: 293826:AMET_RS20410
uniprot id: A6TVM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

293826:AMET RS10620
gene id: 293826:AMET_RS10620
uniprot id: A6TQ40
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

293826:AMET RS15135
gene id: 293826:AMET_RS15135
uniprot id: A6TSP8
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

293826:AMET RS02955
gene id: 293826:AMET_RS02955
uniprot id: A6TKU7
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS17585
gene id: 293826:AMET_RS17585
uniprot id: A6TU37
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS03630
gene id: 293826:AMET_RS03630
uniprot id: A6TL88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

293826:AMET RS12580
gene id: 293826:AMET_RS12580
uniprot id: A6TR80
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

293826:AMET RS15175
gene id: 293826:AMET_RS15175
uniprot id: A6TSQ6
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

293826:AMET RS23625
gene id: 293826:AMET_RS23625
uniprot id: A6TX79
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS17190
gene id: 293826:AMET_RS17190
uniprot id: A6TTV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

293826:AMET RS16840
gene id: 293826:AMET_RS16840
uniprot id: A6TTN7
names: Similarity
messages: Belongs to the peptidase S11 family.

293826:AMET RS03285
gene id: 293826:AMET_RS03285
uniprot id: A6TL16
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

293826:AMET RS23960
gene id: 293826:AMET_RS23960
uniprot id: A6TXE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

293826:AMET RS19495
gene id: 293826:AMET_RS19495
uniprot id: A6TM42
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

293826:AMET RS20000
gene id: 293826:AMET_RS20000
uniprot id: A6TVD9
names: Similarity
messages: Belongs to the DCK/DGK family.

293826:AMET RS14860
gene id: 293826:AMET_RS14860
uniprot id: A6TSJ2
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

293826:AMET RS20700
gene id: 293826:AMET_RS20700
uniprot id: A6TVS9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

293826:AMET RS03245
gene id: 293826:AMET_RS03245
uniprot id: A6TL08
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

293826:AMET RS07780
gene id: 293826:AMET_RS07780
uniprot id: A6TNI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

293826:AMET RS01640
gene id: 293826:AMET_RS01640
uniprot id: A6TK31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

293826:AMET RS23270
gene id: 293826:AMET_RS23270
uniprot id: A6TX09
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

293826:AMET RS11490
gene id: 293826:AMET_RS11490
uniprot id: A6TQL4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS01150
gene id: 293826:AMET_RS01150
uniprot id: A6TJT5
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

293826:AMET RS22300
gene id: 293826:AMET_RS22300
uniprot id: A6TWG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

293826:AMET RS03940
gene id: 293826:AMET_RS03940
uniprot id: A6TLF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

293826:AMET RS01455
gene id: 293826:AMET_RS01455
uniprot id: A6TJZ6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

293826:AMET RS17765
gene id: 293826:AMET_RS17765
uniprot id: A6TU70
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

293826:AMET RS12525
gene id: 293826:AMET_RS12525
uniprot id: A6TR70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

293826:AMET RS13525
gene id: 293826:AMET_RS13525
uniprot id: A6TRS2
names: Similarity
messages: Belongs to the UPF0102 family.

293826:AMET RS06030
gene id: 293826:AMET_RS06030
uniprot id: A6TML3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

293826:AMET RS05055
gene id: 293826:AMET_RS05055
uniprot id: A6TM22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS01485
gene id: 293826:AMET_RS01485
uniprot id: A6TK02
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS02550
gene id: 293826:AMET_RS02550
uniprot id: A6TKL6
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

293826:AMET RS17005
gene id: 293826:AMET_RS17005
uniprot id: A6TTS0
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

293826:AMET RS20540
gene id: 293826:AMET_RS20540
uniprot id: A6TVP9
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

293826:AMET RS08140
gene id: 293826:AMET_RS08140
uniprot id: A6TNQ5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

293826:AMET RS06205
gene id: 293826:AMET_RS06205
uniprot id: A6TMP6
names: Function
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

293826:AMET RS22215
gene id: 293826:AMET_RS22215
uniprot id: A6TWF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

293826:AMET RS02460
gene id: 293826:AMET_RS02460
uniprot id: A6TKJ8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS10845
gene id: 293826:AMET_RS10845
uniprot id: A6TQ87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

293826:AMET RS06920
gene id: 293826:AMET_RS06920
uniprot id: A6TN35
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

293826:AMET RS06155
gene id: 293826:AMET_RS06155
uniprot id: A6TMN6
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

293826:AMET RS00035
gene id: 293826:AMET_RS00035
uniprot id: A6TJ82
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

293826:AMET RS12510
gene id: 293826:AMET_RS12510
uniprot id: A6TR67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

293826:AMET RS02940
gene id: 293826:AMET_RS02940
uniprot id: A6TKU4
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

293826:AMET RS08435
gene id: 293826:AMET_RS08435
uniprot id: A6TNW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

293826:AMET RS15035
gene id: 293826:AMET_RS15035
uniprot id: A6TSM8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

293826:AMET RS15450
gene id: 293826:AMET_RS15450
uniprot id: A6TSW1
names: Similarity
messages: Belongs to the peptidase M18 family.

293826:AMET RS00180
gene id: 293826:AMET_RS00180
uniprot id: A6TJA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

293826:AMET RS11635
gene id: 293826:AMET_RS11635
uniprot id: A6TQP0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

293826:AMET RS01905
gene id: 293826:AMET_RS01905
uniprot id: A6TK84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

293826:AMET RS17860
gene id: 293826:AMET_RS17860
uniprot id: A6TU88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

293826:AMET RS13155
gene id: 293826:AMET_RS13155
uniprot id: A6TRK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

293826:AMET RS03100
gene id: 293826:AMET_RS03100
uniprot id: A6TKX6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS09355
gene id: 293826:AMET_RS09355
uniprot id: A6TN04
names: Similarity
messages: Belongs to the transposase 11 family.

293826:AMET RS14620
gene id: 293826:AMET_RS14620
uniprot id: A6TSE8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS12160
gene id: 293826:AMET_RS12160
uniprot id: A6TQZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

293826:AMET RS06130
gene id: 293826:AMET_RS06130
uniprot id: A6TMN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

293826:AMET RS07185
gene id: 293826:AMET_RS07185
uniprot id: A6TN88
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS15980
gene id: 293826:AMET_RS15980
uniprot id: A6TT66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

293826:AMET RS23615
gene id: 293826:AMET_RS23615
uniprot id: A6TX77
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

293826:AMET RS00130
gene id: 293826:AMET_RS00130
uniprot id: A6TJ96
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS18665
gene id: 293826:AMET_RS18665
uniprot id: A6TUP6
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

293826:AMET RS17915
gene id: 293826:AMET_RS17915
uniprot id: A6TU99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

293826:AMET RS23975
gene id: 293826:AMET_RS23975
uniprot id: A6TXE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

293826:AMET RS16725
gene id: 293826:AMET_RS16725
uniprot id: A6TTL4
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

293826:AMET RS18035
gene id: 293826:AMET_RS18035
uniprot id: A6TUC3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

293826:AMET RS11020
gene id: 293826:AMET_RS11020
uniprot id: A6TQC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

293826:AMET RS04015
gene id: 293826:AMET_RS04015
uniprot id: A6TLH0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

293826:AMET RS20525
gene id: 293826:AMET_RS20525
uniprot id: A6TVP6
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

293826:AMET RS11340
gene id: 293826:AMET_RS11340
uniprot id: A6TQI4
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

293826:AMET RS24440
gene id: 293826:AMET_RS24440
uniprot id: A6TT47
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS11430
gene id: 293826:AMET_RS11430
uniprot id: A6TQK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

293826:AMET RS22145
gene id: 293826:AMET_RS22145
uniprot id: A6TWD6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

293826:AMET RS10720
gene id: 293826:AMET_RS10720
uniprot id: A6TQ62
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

293826:AMET RS01095
gene id: 293826:AMET_RS01095
uniprot id: A6TJS4
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

293826:AMET RS02775
gene id: 293826:AMET_RS02775
uniprot id: A6TKR0
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS17050
gene id: 293826:AMET_RS17050
uniprot id: A6TTS9
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

293826:AMET RS10225
gene id: 293826:AMET_RS10225
uniprot id: A6TPW2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS00020
gene id: 293826:AMET_RS00020
uniprot id: A6TJ79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

293826:AMET RS14220
gene id: 293826:AMET_RS14220
uniprot id: A6TS66
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm

293826:AMET RS11280
gene id: 293826:AMET_RS11280
uniprot id: A6TQH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

293826:AMET RS15810
gene id: 293826:AMET_RS15810
uniprot id: A6TT29
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS17045
gene id: 293826:AMET_RS17045
uniprot id: A6TTS8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS11680
gene id: 293826:AMET_RS11680
uniprot id: A6TQP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

293826:AMET RS23030
gene id: 293826:AMET_RS23030
uniprot id: A6TWW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

293826:AMET RS00195
gene id: 293826:AMET_RS00195
uniprot id: A6TJA7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

293826:AMET RS07930
gene id: 293826:AMET_RS07930
uniprot id: A6TNL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

293826:AMET RS04560
gene id: 293826:AMET_RS04560
uniprot id: A6TLS6
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS13580
gene id: 293826:AMET_RS13580
uniprot id: A6TRT3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

293826:AMET RS06695
gene id: 293826:AMET_RS06695
uniprot id: A6TMY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

293826:AMET RS08290
gene id: 293826:AMET_RS08290
uniprot id: A6TNT5
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

293826:AMET RS01815
gene id: 293826:AMET_RS01815
uniprot id: A6TK66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

293826:AMET RS02320
gene id: 293826:AMET_RS02320
uniprot id: A6TKH3
names: Similarity
messages: Belongs to the MYG1 family.

293826:AMET RS23250
gene id: 293826:AMET_RS23250
uniprot id: A6TX05
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

293826:AMET RS00005
gene id: 293826:AMET_RS00005
uniprot id: A6TJ76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

293826:AMET RS14275
gene id: 293826:AMET_RS14275
uniprot id: A6TS78
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

293826:AMET RS22385
gene id: 293826:AMET_RS22385
uniprot id: A6TWI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

293826:AMET RS00835
gene id: 293826:AMET_RS00835
uniprot id: A6TJM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

293826:AMET RS15550
gene id: 293826:AMET_RS15550
uniprot id: A6TSY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

293826:AMET RS22090
gene id: 293826:AMET_RS22090
uniprot id: A6TWC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

293826:AMET RS03615
gene id: 293826:AMET_RS03615
uniprot id: A6TL85
names: Similarity
messages: Belongs to the bacterial flagellin family.

293826:AMET RS21650
gene id: 293826:AMET_RS21650
uniprot id: A6TW35
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

293826:AMET RS17655
gene id: 293826:AMET_RS17655
uniprot id: A6TU49
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

293826:AMET RS05655
gene id: 293826:AMET_RS05655
uniprot id: A6TME0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

293826:AMET RS18945
gene id: 293826:AMET_RS18945
uniprot id: A6TM42
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

293826:AMET RS14985
gene id: 293826:AMET_RS14985
uniprot id: A6TSL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

293826:AMET RS13370
gene id: 293826:AMET_RS13370
uniprot id: A6TRP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

293826:AMET RS15845
gene id: 293826:AMET_RS15845
uniprot id: A6TT36
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

293826:AMET RS09965
gene id: 293826:AMET_RS09965
uniprot id: A6TPR2
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

293826:AMET RS20520
gene id: 293826:AMET_RS20520
uniprot id: A6TVP5
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.

293826:AMET RS15520
gene id: 293826:AMET_RS15520
uniprot id: A6TSX6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

293826:AMET RS08440
gene id: 293826:AMET_RS08440
uniprot id: A6TNW6
names: Similarity
messages: Belongs to the DSD1 family.

293826:AMET RS20255
gene id: 293826:AMET_RS20255
uniprot id: A6TVI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

293826:AMET RS05305
gene id: 293826:AMET_RS05305
uniprot id: A6TM69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

293826:AMET RS17155
gene id: 293826:AMET_RS17155
uniprot id: A6TTV0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

293826:AMET RS18460
gene id: 293826:AMET_RS18460
uniprot id: A6TUK6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DbpA subfamily.
messages: Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.

293826:AMET RS03475
gene id: 293826:AMET_RS03475
uniprot id: A6TL55
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS12350
gene id: 293826:AMET_RS12350
uniprot id: A6TR35
names: Similarity
messages: Belongs to the asp23 family.

293826:AMET RS02325
gene id: 293826:AMET_RS02325
uniprot id: A6TKH4
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

293826:AMET RS16690
gene id: 293826:AMET_RS16690
uniprot id: A6TTK7
names: Similarity
messages: Belongs to the glutamate synthase family.

293826:AMET RS12135
gene id: 293826:AMET_RS12135
uniprot id: A6TQZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

293826:AMET RS18270
gene id: 293826:AMET_RS18270
uniprot id: A6TUG9
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS22370
gene id: 293826:AMET_RS22370
uniprot id: A6TWI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

293826:AMET RS12445
gene id: 293826:AMET_RS12445
uniprot id: A6TR54
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS19820
gene id: 293826:AMET_RS19820
uniprot id: A6TVA3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

293826:AMET RS15830
gene id: 293826:AMET_RS15830
uniprot id: A6TT33
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS07810
gene id: 293826:AMET_RS07810
uniprot id: A6TNJ5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS11575
gene id: 293826:AMET_RS11575
uniprot id: A6TQM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

293826:AMET RS18090
gene id: 293826:AMET_RS18090
uniprot id: A6TUD5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

293826:AMET RS17570
gene id: 293826:AMET_RS17570
uniprot id: A6TU34
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

293826:AMET RS06260
gene id: 293826:AMET_RS06260
uniprot id: A6TMQ7
names: Similarity
messages: Belongs to the glutamine synthetase family.

293826:AMET RS02990
gene id: 293826:AMET_RS02990
uniprot id: A6TKV4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

293826:AMET RS16695
gene id: 293826:AMET_RS16695
uniprot id: A6TTK8
names: Similarity
messages: Belongs to the UPF0237 family.

293826:AMET RS08180
gene id: 293826:AMET_RS08180
uniprot id: A6TNR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

293826:AMET RS02655
gene id: 293826:AMET_RS02655
uniprot id: A6TKN7
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

293826:AMET RS13540
gene id: 293826:AMET_RS13540
uniprot id: A6TRS5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

293826:AMET RS13385
gene id: 293826:AMET_RS13385
uniprot id: A6TRP7
names: Similarity
messages: Belongs to the MotB family.

293826:AMET RS18465
gene id: 293826:AMET_RS18465
uniprot id: A6TUK7
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Homodimer.

293826:AMET RS11530
gene id: 293826:AMET_RS11530
uniprot id: A6TQL9
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

293826:AMET RS21990
gene id: 293826:AMET_RS21990
uniprot id: A6TWA7
names: Subcellular Location Annotation
messages: Cytoplasm

293826:AMET RS22980
gene id: 293826:AMET_RS22980
uniprot id: A6TWV1
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

293826:AMET RS11610
gene id: 293826:AMET_RS11610
uniprot id: A6TQN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

293826:AMET RS05665
gene id: 293826:AMET_RS05665
uniprot id: A6TME2
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS02800
gene id: 293826:AMET_RS02800
uniprot id: A6TKR5
names: Similarity
messages: Belongs to the UxaA family.

293826:AMET RS23780
gene id: 293826:AMET_RS23780
uniprot id: A6TXB0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

293826:AMET RS01090
gene id: 293826:AMET_RS01090
uniprot id: A6TJS3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

293826:AMET RS01885
gene id: 293826:AMET_RS01885
uniprot id: A6TK80
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS18550
gene id: 293826:AMET_RS18550
uniprot id: A6TUM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

293826:AMET RS01680
gene id: 293826:AMET_RS01680
uniprot id: A6TK39
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

293826:AMET RS13080
gene id: 293826:AMET_RS13080
uniprot id: A6TRI6
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

293826:AMET RS20175
gene id: 293826:AMET_RS20175
uniprot id: A6TVH3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

293826:AMET RS17015
gene id: 293826:AMET_RS17015
uniprot id: A6TTS2
names: Similarity
messages: Belongs to the UPF0234 family.

293826:AMET RS22635
gene id: 293826:AMET_RS22635
uniprot id: A6TWN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

293826:AMET RS04520
gene id: 293826:AMET_RS04520
uniprot id: A6TLR8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS02865
gene id: 293826:AMET_RS02865
uniprot id: A6TKS8
names: Function
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

293826:AMET RS14555
gene id: 293826:AMET_RS14555
uniprot id: A6TSD5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

293826:AMET RS09320
gene id: 293826:AMET_RS09320
uniprot id: A6TPC8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

293826:AMET RS20955
gene id: 293826:AMET_RS20955
uniprot id: A6TVX8
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

293826:AMET RS13315
gene id: 293826:AMET_RS13315
uniprot id: A6TRN3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

293826:AMET RS18850
gene id: 293826:AMET_RS18850
uniprot id: A6TUT2
names: Similarity
messages: Belongs to the EutP/PduV family.

293826:AMET RS02235
gene id: 293826:AMET_RS02235
uniprot id: A6TKF4
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS01390
gene id: 293826:AMET_RS01390
uniprot id: A6TJY2
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

293826:AMET RS01370
gene id: 293826:AMET_RS01370
uniprot id: A6TJX8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

293826:AMET RS23890
gene id: 293826:AMET_RS23890
uniprot id: A6TXD0
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS02575
gene id: 293826:AMET_RS02575
uniprot id: A6TKM1
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

293826:AMET RS04770
gene id: 293826:AMET_RS04770
uniprot id: A6TLW5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

293826:AMET RS00205
gene id: 293826:AMET_RS00205
uniprot id: A6TJA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

293826:AMET RS14460
gene id: 293826:AMET_RS14460
uniprot id: A6TSB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

293826:AMET RS18720
gene id: 293826:AMET_RS18720
uniprot id: A6TUQ7
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS04630
gene id: 293826:AMET_RS04630
uniprot id: A6TLU3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

293826:AMET RS08660
gene id: 293826:AMET_RS08660
uniprot id: A6TNZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS21640
gene id: 293826:AMET_RS21640
uniprot id: A6TW33
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

293826:AMET RS15490
gene id: 293826:AMET_RS15490
uniprot id: A6TSX0
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ser-Ser-Gly.
messages: Cytoplasm

293826:AMET RS04825
gene id: 293826:AMET_RS04825
uniprot id: A6TLX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

293826:AMET RS01870
gene id: 293826:AMET_RS01870
uniprot id: A6TK77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS04975
gene id: 293826:AMET_RS04975
uniprot id: A6TM05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

293826:AMET RS01780
gene id: 293826:AMET_RS01780
uniprot id: A6TK59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

293826:AMET RS08110
gene id: 293826:AMET_RS08110
uniprot id: A6TNP9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

293826:AMET RS01660
gene id: 293826:AMET_RS01660
uniprot id: A6TK35
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS07740
gene id: 293826:AMET_RS07740
uniprot id: A6TNI2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

293826:AMET RS22235
gene id: 293826:AMET_RS22235
uniprot id: A6TWF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

293826:AMET RS13110
gene id: 293826:AMET_RS13110
uniprot id: A6TRJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

293826:AMET RS20310
gene id: 293826:AMET_RS20310
uniprot id: A6TVK1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

293826:AMET RS01065
gene id: 293826:AMET_RS01065
uniprot id: A6TJR8
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

293826:AMET RS12185
gene id: 293826:AMET_RS12185
uniprot id: A6TR03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

293826:AMET RS23110
gene id: 293826:AMET_RS23110
uniprot id: A6TWX8
names: Similarity
messages: Belongs to the UPF0173 family.

293826:AMET RS03465
gene id: 293826:AMET_RS03465
uniprot id: A6TL53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

293826:AMET RS14280
gene id: 293826:AMET_RS14280
uniprot id: A6TS79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

293826:AMET RS16260
gene id: 293826:AMET_RS16260
uniprot id: A6TTC1
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS05840
gene id: 293826:AMET_RS05840
uniprot id: A6TMH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

293826:AMET RS15735
gene id: 293826:AMET_RS15735
uniprot id: A6TT15
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

293826:AMET RS17360
gene id: 293826:AMET_RS17360
uniprot id: A6TTZ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS19110
gene id: 293826:AMET_RS19110
uniprot id: A6TUX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

293826:AMET RS11525
gene id: 293826:AMET_RS11525
uniprot id: A6TQL8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS23035
gene id: 293826:AMET_RS23035
uniprot id: A6TWW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

293826:AMET RS00030
gene id: 293826:AMET_RS00030
uniprot id: A6TJ81
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

293826:AMET RS18865
gene id: 293826:AMET_RS18865
uniprot id: A6TUT5
names: Function
names: PTM
names: Similarity
messages: Belongs to the glycyl radical enzyme (GRE) family. CutC subfamily.
messages: Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde.
messages: Requires the activating protein CutD to generate the key active site glycyl radical on Gly-820 that is involved in catalysis.

293826:AMET RS05045
gene id: 293826:AMET_RS05045
uniprot id: A6TM20
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

293826:AMET RS11480
gene id: 293826:AMET_RS11480
uniprot id: A6TQL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

293826:AMET RS19090
gene id: 293826:AMET_RS19090
uniprot id: A6TUX0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

293826:AMET RS22285
gene id: 293826:AMET_RS22285
uniprot id: A6TWG4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

293826:AMET RS02445
gene id: 293826:AMET_RS02445
uniprot id: A6TKJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

293826:AMET RS16645
gene id: 293826:AMET_RS16645
uniprot id: A6TTJ8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

293826:AMET RS22670
gene id: 293826:AMET_RS22670
uniprot id: A6TT36
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

293826:AMET RS19325
gene id: 293826:AMET_RS19325
uniprot id: A6TV09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

293826:AMET RS23690
gene id: 293826:AMET_RS23690
uniprot id: A6TX90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS08805
gene id: 293826:AMET_RS08805
uniprot id: A6TM42
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

293826:AMET RS13255
gene id: 293826:AMET_RS13255
uniprot id: A6TRM1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.

293826:AMET RS03880
gene id: 293826:AMET_RS03880
uniprot id: A6TLE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

293826:AMET RS00380
gene id: 293826:AMET_RS00380
uniprot id: A6TJD5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

293826:AMET RS14600
gene id: 293826:AMET_RS14600
uniprot id: A6TSE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

293826:AMET RS16775
gene id: 293826:AMET_RS16775
uniprot id: A6TTM4
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

293826:AMET RS01925
gene id: 293826:AMET_RS01925
uniprot id: A6TK88
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

293826:AMET RS22430
gene id: 293826:AMET_RS22430
uniprot id: A6TWJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

293826:AMET RS05270
gene id: 293826:AMET_RS05270
uniprot id: A6TM62
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

293826:AMET RS09340
gene id: 293826:AMET_RS09340
uniprot id: A6TPD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

293826:AMET RS10745
gene id: 293826:AMET_RS10745
uniprot id: A6TQ67
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS13795
gene id: 293826:AMET_RS13795
uniprot id: A6TRX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

293826:AMET RS22900
gene id: 293826:AMET_RS22900
uniprot id: A6TWT5
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS14385
gene id: 293826:AMET_RS14385
uniprot id: A6TSA1
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS14130
gene id: 293826:AMET_RS14130
uniprot id: A6TS48
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS20455
gene id: 293826:AMET_RS20455
uniprot id: A6TVN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

293826:AMET RS04380
gene id: 293826:AMET_RS04380
uniprot id: A6TLP3
names: Similarity
messages: Belongs to the EamA transporter family.

293826:AMET RS13650
gene id: 293826:AMET_RS13650
uniprot id: A6TRU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

293826:AMET RS06120
gene id: 293826:AMET_RS06120
uniprot id: A6TMN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS02565
gene id: 293826:AMET_RS02565
uniprot id: A6TKL9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

293826:AMET RS20905
gene id: 293826:AMET_RS20905
uniprot id: A6TVW8
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

293826:AMET RS22505
gene id: 293826:AMET_RS22505
uniprot id: A6TWK9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

293826:AMET RS24640
gene id: 293826:AMET_RS24640
uniprot id: A6TT38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane

293826:AMET RS12145
gene id: 293826:AMET_RS12145
uniprot id: A6TQZ5
names: Similarity
messages: Belongs to the UPF0297 family.

293826:AMET RS03010
gene id: 293826:AMET_RS03010
uniprot id: A6TKV8
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS06210
gene id: 293826:AMET_RS06210
uniprot id: A6TMP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

293826:AMET RS13035
gene id: 293826:AMET_RS13035
uniprot id: A6TRH7
names: Similarity
messages: Belongs to the peptidase S11 family.

293826:AMET RS22225
gene id: 293826:AMET_RS22225
uniprot id: A6TWF2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

293826:AMET RS23985
gene id: 293826:AMET_RS23985
uniprot id: A6TXF0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

293826:AMET RS17530
gene id: 293826:AMET_RS17530
uniprot id: A6TU26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

293826:AMET RS13805
gene id: 293826:AMET_RS13805
uniprot id: A6TRX7
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

293826:AMET RS15220
gene id: 293826:AMET_RS15220
uniprot id: A6TSR6
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

293826:AMET RS00950
gene id: 293826:AMET_RS00950
uniprot id: A6TJP6
names: Similarity
messages: Belongs to the peptidase S41A family.

293826:AMET RS17550
gene id: 293826:AMET_RS17550
uniprot id: A6TU30
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

293826:AMET RS23980
gene id: 293826:AMET_RS23980
uniprot id: A6TXE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

293826:AMET RS08105
gene id: 293826:AMET_RS08105
uniprot id: A6TNP8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

293826:AMET RS05875
gene id: 293826:AMET_RS05875
uniprot id: A6TMI1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

293826:AMET RS18220
gene id: 293826:AMET_RS18220
uniprot id: A6TUF9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

293826:AMET RS15435
gene id: 293826:AMET_RS15435
uniprot id: A6TSV8
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS07985
gene id: 293826:AMET_RS07985
uniprot id: A6TNM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Cytoplasm

293826:AMET RS16380
gene id: 293826:AMET_RS16380
uniprot id: A6TTE3
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

293826:AMET RS13625
gene id: 293826:AMET_RS13625
uniprot id: A6TRU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

293826:AMET RS20935
gene id: 293826:AMET_RS20935
uniprot id: A6TVX4
names: Similarity
messages: Belongs to the YciI family.

293826:AMET RS09905
gene id: 293826:AMET_RS09905
uniprot id: A6TPQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS14720
gene id: 293826:AMET_RS14720
uniprot id: A6TSG6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

293826:AMET RS11625
gene id: 293826:AMET_RS11625
uniprot id: A6TQN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

293826:AMET RS22515
gene id: 293826:AMET_RS22515
uniprot id: A6TWL1
names: Similarity
messages: Belongs to the ycf81 family.

293826:AMET RS22825
gene id: 293826:AMET_RS22825
uniprot id: A6TWS0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

293826:AMET RS04890
gene id: 293826:AMET_RS04890
uniprot id: A6TLY8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

293826:AMET RS14390
gene id: 293826:AMET_RS14390
uniprot id: A6TSA2
names: Similarity
messages: Belongs to the cytochrome c-552 family.

293826:AMET RS08275
gene id: 293826:AMET_RS08275
uniprot id: A6TNT2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

293826:AMET RS04090
gene id: 293826:AMET_RS04090
uniprot id: A6TLI5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

293826:AMET RS18055
gene id: 293826:AMET_RS18055
uniprot id: A6TUC7
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

293826:AMET RS03035
gene id: 293826:AMET_RS03035
uniprot id: A6TKW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

293826:AMET RS22005
gene id: 293826:AMET_RS22005
uniprot id: A6TWB0
names: Similarity
messages: Belongs to the asparagine synthetase family.

293826:AMET RS22975
gene id: 293826:AMET_RS22975
uniprot id: A6TWV0
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

293826:AMET RS10315
gene id: 293826:AMET_RS10315
uniprot id: A6TPY1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

293826:AMET RS07330
gene id: 293826:AMET_RS07330
uniprot id: A6TNB0
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS18245
gene id: 293826:AMET_RS18245
uniprot id: A6TUG4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS06750
gene id: 293826:AMET_RS06750
uniprot id: A6TMZ9
names: Similarity
messages: Belongs to the SleB family.

293826:AMET RS14305
gene id: 293826:AMET_RS14305
uniprot id: A6TS85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

293826:AMET RS15960
gene id: 293826:AMET_RS15960
uniprot id: A6TT60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

293826:AMET RS00615
gene id: 293826:AMET_RS00615
uniprot id: A6TJI2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

293826:AMET RS14830
gene id: 293826:AMET_RS14830
uniprot id: A6TSI6
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

293826:AMET RS02395
gene id: 293826:AMET_RS02395
uniprot id: A6TKI5
names: Similarity
messages: Belongs to the peptidase S66 family.

293826:AMET RS19245
gene id: 293826:AMET_RS19245
uniprot id: A6TN04
names: Similarity
messages: Belongs to the transposase 11 family.

293826:AMET RS15145
gene id: 293826:AMET_RS15145
uniprot id: A6TSQ0
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS00520
gene id: 293826:AMET_RS00520
uniprot id: A6TJG3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

293826:AMET RS15310
gene id: 293826:AMET_RS15310
uniprot id: A6TST5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

293826:AMET RS00310
gene id: 293826:AMET_RS00310
uniprot id: A6TJC1
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

293826:AMET RS00490
gene id: 293826:AMET_RS00490
uniprot id: A6TJF7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

293826:AMET RS22990
gene id: 293826:AMET_RS22990
uniprot id: A6TWV3
names: Similarity
messages: Belongs to the GerABKA family.

293826:AMET RS18905
gene id: 293826:AMET_RS18905
uniprot id: A6TUU3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS04840
gene id: 293826:AMET_RS04840
uniprot id: A6TLX8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

293826:AMET RS16095
gene id: 293826:AMET_RS16095
uniprot id: A6TT91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

293826:AMET RS15770
gene id: 293826:AMET_RS15770
uniprot id: A6TT22
names: Similarity
messages: Belongs to the GerABKA family.

293826:AMET RS05340
gene id: 293826:AMET_RS05340
uniprot id: A6TM76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

293826:AMET RS00485
gene id: 293826:AMET_RS00485
uniprot id: A6TJF6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

293826:AMET RS06180
gene id: 293826:AMET_RS06180
uniprot id: A6TMP1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

293826:AMET RS16760
gene id: 293826:AMET_RS16760
uniprot id: A6TTM1
names: Subcellular Location Annotation
messages: Cytoplasm

293826:AMET RS06345
gene id: 293826:AMET_RS06345
uniprot id: A6TMS1
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

293826:AMET RS20865
gene id: 293826:AMET_RS20865
uniprot id: A6TVW0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

293826:AMET RS05925
gene id: 293826:AMET_RS05925
uniprot id: A6TMJ1
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

293826:AMET RS09895
gene id: 293826:AMET_RS09895
uniprot id: A6TPP8
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS05325
gene id: 293826:AMET_RS05325
uniprot id: A6TM73
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

293826:AMET RS06255
gene id: 293826:AMET_RS06255
uniprot id: A6TMQ6
names: Similarity
messages: Belongs to the IlvD/Edd family.

293826:AMET RS13840
gene id: 293826:AMET_RS13840
uniprot id: A6TRY4
names: Similarity
messages: Belongs to the YggT family.

293826:AMET RS13720
gene id: 293826:AMET_RS13720
uniprot id: A6TRW0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

293826:AMET RS22410
gene id: 293826:AMET_RS22410
uniprot id: A6TWI9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

293826:AMET RS03065
gene id: 293826:AMET_RS03065
uniprot id: A6TKW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

293826:AMET RS23590
gene id: 293826:AMET_RS23590
uniprot id: A6TX72
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

293826:AMET RS20650
gene id: 293826:AMET_RS20650
uniprot id: A6TVR9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS02640
gene id: 293826:AMET_RS02640
uniprot id: A6TKN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

293826:AMET RS10880
gene id: 293826:AMET_RS10880
uniprot id: A6TQ93
names: Similarity
messages: Belongs to the asparaginase 1 family.

293826:AMET RS23945
gene id: 293826:AMET_RS23945
uniprot id: A6TXE1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

293826:AMET RS19040
gene id: 293826:AMET_RS19040
uniprot id: A6TUW4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

293826:AMET RS20355
gene id: 293826:AMET_RS20355
uniprot id: A6TVL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

293826:AMET RS22435
gene id: 293826:AMET_RS22435
uniprot id: A6TWJ4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

293826:AMET RS16015
gene id: 293826:AMET_RS16015
uniprot id: A6TT74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

293826:AMET RS18385
gene id: 293826:AMET_RS18385
uniprot id: A6TUJ1
names: Similarity
messages: Belongs to the EamA transporter family.

293826:AMET RS13595
gene id: 293826:AMET_RS13595
uniprot id: A6TRT6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

293826:AMET RS17995
gene id: 293826:AMET_RS17995
uniprot id: A6TUB5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

293826:AMET RS07145
gene id: 293826:AMET_RS07145
uniprot id: A6TN80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

293826:AMET RS20850
gene id: 293826:AMET_RS20850
uniprot id: A6TVV7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

293826:AMET RS10875
gene id: 293826:AMET_RS10875
uniprot id: A6TQ92
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

293826:AMET RS03965
gene id: 293826:AMET_RS03965
uniprot id: A6TLF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

293826:AMET RS17035
gene id: 293826:AMET_RS17035
uniprot id: A6TTS6
names: Similarity
messages: Belongs to the Dps family.

293826:AMET RS10675
gene id: 293826:AMET_RS10675
uniprot id: A6TQ52
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

293826:AMET RS12290
gene id: 293826:AMET_RS12290
uniprot id: A6TR23
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Homododecamer.

293826:AMET RS15790
gene id: 293826:AMET_RS15790
uniprot id: A6TT26
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

293826:AMET RS19065
gene id: 293826:AMET_RS19065
uniprot id: A6TUW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

293826:AMET RS15210
gene id: 293826:AMET_RS15210
uniprot id: A6TSR3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

293826:AMET RS13665
gene id: 293826:AMET_RS13665
uniprot id: A6TRV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

293826:AMET RS18075
gene id: 293826:AMET_RS18075
uniprot id: A6TUD1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

293826:AMET RS23595
gene id: 293826:AMET_RS23595
uniprot id: A6TX73
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

293826:AMET RS18300
gene id: 293826:AMET_RS18300
uniprot id: A6TUH5
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

293826:AMET RS18955
gene id: 293826:AMET_RS18955
uniprot id: A6TUV3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

293826:AMET RS11630
gene id: 293826:AMET_RS11630
uniprot id: A6TQN9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

293826:AMET RS02780
gene id: 293826:AMET_RS02780
uniprot id: A6TKR1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

293826:AMET RS14180
gene id: 293826:AMET_RS14180
uniprot id: A6TS58
names: Similarity
messages: Belongs to the UPF0749 family.

293826:AMET RS10700
gene id: 293826:AMET_RS10700
uniprot id: A6TQ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspH family.
messages: Spore core

293826:AMET RS11620
gene id: 293826:AMET_RS11620
uniprot id: A6TQN7
names: Similarity
messages: Belongs to the RecJ family.

293826:AMET RS02880
gene id: 293826:AMET_RS02880
uniprot id: A6TKT1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

293826:AMET RS19310
gene id: 293826:AMET_RS19310
uniprot id: A6TV06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

293826:AMET RS10340
gene id: 293826:AMET_RS10340
uniprot id: A6TPY6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

293826:AMET RS03250
gene id: 293826:AMET_RS03250
uniprot id: A6TL09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

293826:AMET RS04830
gene id: 293826:AMET_RS04830
uniprot id: A6TLX6
names: Similarity
messages: Belongs to the FBPase class 3 family.

293826:AMET RS01790
gene id: 293826:AMET_RS01790
uniprot id: A6TK61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

293826:AMET RS16305
gene id: 293826:AMET_RS16305
uniprot id: A6TTC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS06910
gene id: 293826:AMET_RS06910
uniprot id: A6TN32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

293826:AMET RS11565
gene id: 293826:AMET_RS11565
uniprot id: A6TQM5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

293826:AMET RS04025
gene id: 293826:AMET_RS04025
uniprot id: A6TLH2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

293826:AMET RS01160
gene id: 293826:AMET_RS01160
uniprot id: A6TJT7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

293826:AMET RS24450
gene id: 293826:AMET_RS24450
uniprot id: A6TT82
names: Similarity
messages: Belongs to the peptidase C40 family.

293826:AMET RS09365
gene id: 293826:AMET_RS09365
uniprot id: A6TPD8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

293826:AMET RS13800
gene id: 293826:AMET_RS13800
uniprot id: A6TRX6
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

293826:AMET RS08955
gene id: 293826:AMET_RS08955
uniprot id: A6TP50
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

293826:AMET RS15515
gene id: 293826:AMET_RS15515
uniprot id: A6TSX5
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

293826:AMET RS14525
gene id: 293826:AMET_RS14525
uniprot id: A6TSC9
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

293826:AMET RS20260
gene id: 293826:AMET_RS20260
uniprot id: A6TVJ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

293826:AMET RS05010
gene id: 293826:AMET_RS05010
uniprot id: A6TM12
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS23105
gene id: 293826:AMET_RS23105
uniprot id: A6TWX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

293826:AMET RS17855
gene id: 293826:AMET_RS17855
uniprot id: A6TU87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

293826:AMET RS00805
gene id: 293826:AMET_RS00805
uniprot id: A6TJL9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

293826:AMET RS01755
gene id: 293826:AMET_RS01755
uniprot id: A6TK54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

293826:AMET RS16205
gene id: 293826:AMET_RS16205
uniprot id: A6TTB3
names: Similarity
messages: Belongs to the HsdR family.

293826:AMET RS17170
gene id: 293826:AMET_RS17170
uniprot id: A6TTV3
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

293826:AMET RS09845
gene id: 293826:AMET_RS09845
uniprot id: A6TPN8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS14075
gene id: 293826:AMET_RS14075
uniprot id: A6TS37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

293826:AMET RS00545
gene id: 293826:AMET_RS00545
uniprot id: A6TJG8
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

293826:AMET RS01805
gene id: 293826:AMET_RS01805
uniprot id: A6TK64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

293826:AMET RS03540
gene id: 293826:AMET_RS03540
uniprot id: A6TL68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

293826:AMET RS14240
gene id: 293826:AMET_RS14240
uniprot id: A6TS70
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

293826:AMET RS18840
gene id: 293826:AMET_RS18840
uniprot id: A6TUT0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

293826:AMET RS12400
gene id: 293826:AMET_RS12400
uniprot id: A6TR45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

293826:AMET RS08035
gene id: 293826:AMET_RS08035
uniprot id: A6TNN7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

293826:AMET RS14945
gene id: 293826:AMET_RS14945
uniprot id: A6TSL0
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS23825
gene id: 293826:AMET_RS23825
uniprot id: A6TXB7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

293826:AMET RS15940
gene id: 293826:AMET_RS15940
uniprot id: A6TT56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

293826:AMET RS23225
gene id: 293826:AMET_RS23225
uniprot id: A6TX00
names: Similarity
messages: Belongs to the transketolase family.

293826:AMET RS03520
gene id: 293826:AMET_RS03520
uniprot id: A6TL64
names: Similarity
messages: Belongs to the phosphohexose mutase family.

293826:AMET RS03795
gene id: 293826:AMET_RS03795
uniprot id: A6TLC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS00855
gene id: 293826:AMET_RS00855
uniprot id: A6TJM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

293826:AMET RS13065
gene id: 293826:AMET_RS13065
uniprot id: A6TRI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cytoplasm
messages: Homodimer or homotetramer.

293826:AMET RS16710
gene id: 293826:AMET_RS16710
uniprot id: A6TTL1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS08245
gene id: 293826:AMET_RS08245
uniprot id: A6TNS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

293826:AMET RS00430
gene id: 293826:AMET_RS00430
uniprot id: A6TJE5
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

293826:AMET RS17970
gene id: 293826:AMET_RS17970
uniprot id: A6TUB0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

293826:AMET RS13265
gene id: 293826:AMET_RS13265
uniprot id: A6TRM3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

293826:AMET RS22380
gene id: 293826:AMET_RS22380
uniprot id: A6TWI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

293826:AMET RS14175
gene id: 293826:AMET_RS14175
uniprot id: A6TS57
names: Similarity
messages: Belongs to the UPF0749 family.

293826:AMET RS15825
gene id: 293826:AMET_RS15825
uniprot id: A6TT32
names: Similarity
messages: Belongs to the GerABKA family.

293826:AMET RS00355
gene id: 293826:AMET_RS00355
uniprot id: A6TJD0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

293826:AMET RS22945
gene id: 293826:AMET_RS22945
uniprot id: A6TWU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

293826:AMET RS05290
gene id: 293826:AMET_RS05290
uniprot id: A6TM66
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

293826:AMET RS19770
gene id: 293826:AMET_RS19770
uniprot id: A6TV93
names: Similarity
messages: Belongs to the peptidase S14 family.

293826:AMET RS12685
gene id: 293826:AMET_RS12685
uniprot id: A6TRA2
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

293826:AMET RS22855
gene id: 293826:AMET_RS22855
uniprot id: A6TWS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

293826:AMET RS15440
gene id: 293826:AMET_RS15440
uniprot id: A6TSV9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

293826:AMET RS18470
gene id: 293826:AMET_RS18470
uniprot id: A6TUK8
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.

293826:AMET RS11685
gene id: 293826:AMET_RS11685
uniprot id: A6TQQ0
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

293826:AMET RS14535
gene id: 293826:AMET_RS14535
uniprot id: A6TSD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

293826:AMET RS13500
gene id: 293826:AMET_RS13500
uniprot id: A6TRR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

293826:AMET RS16700
gene id: 293826:AMET_RS16700
uniprot id: A6TTK9
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

293826:AMET RS01295
gene id: 293826:AMET_RS01295
uniprot id: A6TJW3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS02975
gene id: 293826:AMET_RS02975
uniprot id: A6TKV1
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

293826:AMET RS13380
gene id: 293826:AMET_RS13380
uniprot id: A6TRP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

293826:AMET RS23165
gene id: 293826:AMET_RS23165
uniprot id: A6TWY9
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

293826:AMET RS01800
gene id: 293826:AMET_RS01800
uniprot id: A6TK63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

293826:AMET RS01355
gene id: 293826:AMET_RS01355
uniprot id: A6TJX5
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

293826:AMET RS12925
gene id: 293826:AMET_RS12925
uniprot id: A6TRF5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

293826:AMET RS07575
gene id: 293826:AMET_RS07575
uniprot id: A6TNF4
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

293826:AMET RS06015
gene id: 293826:AMET_RS06015
uniprot id: A6TML0
names: Similarity
messages: Belongs to the CvfB family.

293826:AMET RS04320
gene id: 293826:AMET_RS04320
uniprot id: A6TLM9
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

293826:AMET RS17980
gene id: 293826:AMET_RS17980
uniprot id: A6TUB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

293826:AMET RS13000
gene id: 293826:AMET_RS13000
uniprot id: A6TRH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

293826:AMET RS02295
gene id: 293826:AMET_RS02295
uniprot id: A6TKG8
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS22335
gene id: 293826:AMET_RS22335
uniprot id: A6TWH4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

293826:AMET RS17200
gene id: 293826:AMET_RS17200
uniprot id: A6TTV9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

293826:AMET RS01025
gene id: 293826:AMET_RS01025
uniprot id: A6TJR1
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS04080
gene id: 293826:AMET_RS04080
uniprot id: A6TLI3
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

293826:AMET RS02525
gene id: 293826:AMET_RS02525
uniprot id: A6TKL1
names: Similarity
messages: Belongs to the IlvD/Edd family.

293826:AMET RS20120
gene id: 293826:AMET_RS20120
uniprot id: A6TVG3
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

293826:AMET RS10680
gene id: 293826:AMET_RS10680
uniprot id: A6TQ53
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

293826:AMET RS12390
gene id: 293826:AMET_RS12390
uniprot id: A6TR43
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

293826:AMET RS21115
gene id: 293826:AMET_RS21115
uniprot id: A6TW07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

293826:AMET RS07150
gene id: 293826:AMET_RS07150
uniprot id: A6TN81
names: Similarity
messages: Belongs to the pirin family.

293826:AMET RS18800
gene id: 293826:AMET_RS18800
uniprot id: A6TUS2
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

293826:AMET RS02420
gene id: 293826:AMET_RS02420
uniprot id: A6TKJ0
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

293826:AMET RS07215
gene id: 293826:AMET_RS07215
uniprot id: A6TN94
names: Similarity
messages: Belongs to the UPF0251 family.

293826:AMET RS09335
gene id: 293826:AMET_RS09335
uniprot id: A6TPD1
names: Similarity
messages: Belongs to the peptidase S58 family.

293826:AMET RS02635
gene id: 293826:AMET_RS02635
uniprot id: A6TKN3
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS20515
gene id: 293826:AMET_RS20515
uniprot id: A6TVP4
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

293826:AMET RS00755
gene id: 293826:AMET_RS00755
uniprot id: A6TJK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

293826:AMET RS17730
gene id: 293826:AMET_RS17730
uniprot id: A6TU63
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

293826:AMET RS00120
gene id: 293826:AMET_RS00120
uniprot id: A6TJ94
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

293826:AMET RS17475
gene id: 293826:AMET_RS17475
uniprot id: A6TM42
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

293826:AMET RS12950
gene id: 293826:AMET_RS12950
uniprot id: A6TRG0
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

293826:AMET RS13390
gene id: 293826:AMET_RS13390
uniprot id: A6TRP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

293826:AMET RS03085
gene id: 293826:AMET_RS03085
uniprot id: A6TKX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

293826:AMET RS10190
gene id: 293826:AMET_RS10190
uniprot id: A6TPV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS18675
gene id: 293826:AMET_RS18675
uniprot id: A6TUP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

293826:AMET RS20345
gene id: 293826:AMET_RS20345
uniprot id: A6TVK8
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

293826:AMET RS00715
gene id: 293826:AMET_RS00715
uniprot id: A6TJK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

293826:AMET RS16360
gene id: 293826:AMET_RS16360
uniprot id: A6TTD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS23330
gene id: 293826:AMET_RS23330
uniprot id: A6TX21
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS23140
gene id: 293826:AMET_RS23140
uniprot id: A6TWY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

293826:AMET RS14995
gene id: 293826:AMET_RS14995
uniprot id: A6TSM0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

293826:AMET RS05245
gene id: 293826:AMET_RS05245
uniprot id: A6TM57
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

293826:AMET RS13590
gene id: 293826:AMET_RS13590
uniprot id: A6TRT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

293826:AMET RS11005
gene id: 293826:AMET_RS11005
uniprot id: A6TQB9
names: Similarity
messages: Belongs to the IMPACT family.

293826:AMET RS20915
gene id: 293826:AMET_RS20915
uniprot id: A6TVX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

293826:AMET RS22470
gene id: 293826:AMET_RS22470
uniprot id: A6TWK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

293826:AMET RS08470
gene id: 293826:AMET_RS08470
uniprot id: A6TNX2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

293826:AMET RS16445
gene id: 293826:AMET_RS16445
uniprot id: A6TTF8
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

293826:AMET RS22280
gene id: 293826:AMET_RS22280
uniprot id: A6TWG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

293826:AMET RS13850
gene id: 293826:AMET_RS13850
uniprot id: A6TRY6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

293826:AMET RS06815
gene id: 293826:AMET_RS06815
uniprot id: A6TN12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

293826:AMET RS17555
gene id: 293826:AMET_RS17555
uniprot id: A6TU31
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

293826:AMET RS03930
gene id: 293826:AMET_RS03930
uniprot id: A6TLF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

293826:AMET RS13865
gene id: 293826:AMET_RS13865
uniprot id: A6TRZ0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

293826:AMET RS18860
gene id: 293826:AMET_RS18860
uniprot id: A6TUT4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S-adenosyl-L-methionine (SAM).

293826:AMET RS01235
gene id: 293826:AMET_RS01235
uniprot id: A6TJV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

293826:AMET RS17245
gene id: 293826:AMET_RS17245
uniprot id: A6TTW8
names: Similarity
messages: Belongs to the OsmC/Ohr family.

293826:AMET RS15760
gene id: 293826:AMET_RS15760
uniprot id: A6TT20
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

293826:AMET RS11455
gene id: 293826:AMET_RS11455
uniprot id: A6TQK7
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

293826:AMET RS01580
gene id: 293826:AMET_RS01580
uniprot id: A6TK21
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS12120
gene id: 293826:AMET_RS12120
uniprot id: A6TQY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

293826:AMET RS04540
gene id: 293826:AMET_RS04540
uniprot id: A6TLS2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

293826:AMET RS09860
gene id: 293826:AMET_RS09860
uniprot id: A6TPP1
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS02335
gene id: 293826:AMET_RS02335
uniprot id: A6TKH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

293826:AMET RS13510
gene id: 293826:AMET_RS13510
uniprot id: A6TRR9
names: Similarity
messages: Belongs to the DprA/Smf family.

293826:AMET RS13085
gene id: 293826:AMET_RS13085
uniprot id: A6TRI7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

293826:AMET RS20240
gene id: 293826:AMET_RS20240
uniprot id: A6TVI6
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS06560
gene id: 293826:AMET_RS06560
uniprot id: A6TMW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS07200
gene id: 293826:AMET_RS07200
uniprot id: A6TN91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

293826:AMET RS13905
gene id: 293826:AMET_RS13905
uniprot id: A6TRZ8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS15895
gene id: 293826:AMET_RS15895
uniprot id: A6TT46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

293826:AMET RS05265
gene id: 293826:AMET_RS05265
uniprot id: A6TM61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

293826:AMET RS23155
gene id: 293826:AMET_RS23155
uniprot id: A6TWY7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS01750
gene id: 293826:AMET_RS01750
uniprot id: A6TK53
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS23580
gene id: 293826:AMET_RS23580
uniprot id: A6TX70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS04490
gene id: 293826:AMET_RS04490
uniprot id: A6TLR3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

293826:AMET RS09900
gene id: 293826:AMET_RS09900
uniprot id: A6TPP9
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS19920
gene id: 293826:AMET_RS19920
uniprot id: A6TVC3
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

293826:AMET RS16980
gene id: 293826:AMET_RS16980
uniprot id: A6TTR5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

293826:AMET RS15740
gene id: 293826:AMET_RS15740
uniprot id: A6TT16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

293826:AMET RS23705
gene id: 293826:AMET_RS23705
uniprot id: A6TX93
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS02795
gene id: 293826:AMET_RS02795
uniprot id: A6TKR4
names: Similarity
messages: Belongs to the mannitol dehydrogenase family. UxaB subfamily.

293826:AMET RS23965
gene id: 293826:AMET_RS23965
uniprot id: A6TXE5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

293826:AMET RS22275
gene id: 293826:AMET_RS22275
uniprot id: A6TWG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

293826:AMET RS23290
gene id: 293826:AMET_RS23290
uniprot id: A6TX13
names: Similarity
messages: Belongs to the hemerythrin family.

293826:AMET RS17990
gene id: 293826:AMET_RS17990
uniprot id: A6TUB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS03450
gene id: 293826:AMET_RS03450
uniprot id: A6TL50
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS01795
gene id: 293826:AMET_RS01795
uniprot id: A6TK62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

293826:AMET RS20945
gene id: 293826:AMET_RS20945
uniprot id: A6TVX6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

293826:AMET RS03610
gene id: 293826:AMET_RS03610
uniprot id: A6TL84
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

293826:AMET RS05940
gene id: 293826:AMET_RS05940
uniprot id: A6TMJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

293826:AMET RS05725
gene id: 293826:AMET_RS05725
uniprot id: A6TMF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS21150
gene id: 293826:AMET_RS21150
uniprot id: A6TW14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

293826:AMET RS01735
gene id: 293826:AMET_RS01735
uniprot id: A6TK50
names: Similarity
messages: Belongs to the LacAB/RpiB family.

293826:AMET RS20220
gene id: 293826:AMET_RS20220
uniprot id: A6TVI2
names: Similarity
messages: Belongs to the leucine-binding protein family.

293826:AMET RS24435
gene id: 293826:AMET_RS24435
uniprot id: A6TT38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane

293826:AMET RS11030
gene id: 293826:AMET_RS11030
uniprot id: A6TQC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

293826:AMET RS07535
gene id: 293826:AMET_RS07535
uniprot id: A6TNE6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

293826:AMET RS08355
gene id: 293826:AMET_RS08355
uniprot id: A6TNU9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS05260
gene id: 293826:AMET_RS05260
uniprot id: A6TM60
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

293826:AMET RS16245
gene id: 293826:AMET_RS16245
uniprot id: A6TTB8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS03055
gene id: 293826:AMET_RS03055
uniprot id: A6TKW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

293826:AMET RS18620
gene id: 293826:AMET_RS18620
uniprot id: A6TUN7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

293826:AMET RS05865
gene id: 293826:AMET_RS05865
uniprot id: A6TMH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

293826:AMET RS22595
gene id: 293826:AMET_RS22595
uniprot id: A6TWM7
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

293826:AMET RS13120
gene id: 293826:AMET_RS13120
uniprot id: A6TRJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

293826:AMET RS01130
gene id: 293826:AMET_RS01130
uniprot id: A6TJT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

293826:AMET RS20335
gene id: 293826:AMET_RS20335
uniprot id: A6TVK6
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

293826:AMET RS16620
gene id: 293826:AMET_RS16620
uniprot id: A6TTJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

293826:AMET RS02620
gene id: 293826:AMET_RS02620
uniprot id: A6TKN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

293826:AMET RS16600
gene id: 293826:AMET_RS16600
uniprot id: A6TTI9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

293826:AMET RS03565
gene id: 293826:AMET_RS03565
uniprot id: A6TL74
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

293826:AMET RS13365
gene id: 293826:AMET_RS13365
uniprot id: A6TRP3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS23065
gene id: 293826:AMET_RS23065
uniprot id: A6TWW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

293826:AMET RS15485
gene id: 293826:AMET_RS15485
uniprot id: A6TSW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

293826:AMET RS22495
gene id: 293826:AMET_RS22495
uniprot id: A6TWK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

293826:AMET RS22250
gene id: 293826:AMET_RS22250
uniprot id: A6TWF7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

293826:AMET RS20675
gene id: 293826:AMET_RS20675
uniprot id: A6TVS4
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

293826:AMET RS14285
gene id: 293826:AMET_RS14285
uniprot id: A6TS80
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

293826:AMET RS00110
gene id: 293826:AMET_RS00110
uniprot id: A6TJ92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

293826:AMET RS11445
gene id: 293826:AMET_RS11445
uniprot id: A6TQK5
names: Similarity
messages: Belongs to the RutC family.

293826:AMET RS03500
gene id: 293826:AMET_RS03500
uniprot id: A6TL60
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

293826:AMET RS24395
gene id: 293826:AMET_RS24395
uniprot id: A6TRQ2
names: Similarity
messages: Belongs to the FlgD family.

293826:AMET RS04665
gene id: 293826:AMET_RS04665
uniprot id: A6TLV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

293826:AMET RS17545
gene id: 293826:AMET_RS17545
uniprot id: A6TU29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

293826:AMET RS22620
gene id: 293826:AMET_RS22620
uniprot id: A6TWM9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

293826:AMET RS15745
gene id: 293826:AMET_RS15745
uniprot id: A6TT17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

293826:AMET RS01310
gene id: 293826:AMET_RS01310
uniprot id: A6TJW6
names: Similarity
messages: Belongs to the EutP/PduV family.

293826:AMET RS08420
gene id: 293826:AMET_RS08420
uniprot id: A6TNW2
names: Similarity
messages: Belongs to the CinA family.

293826:AMET RS04800
gene id: 293826:AMET_RS04800
uniprot id: A6TLX0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

293826:AMET RS20885
gene id: 293826:AMET_RS20885
uniprot id: A6TVW4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

293826:AMET RS23925
gene id: 293826:AMET_RS23925
uniprot id: A6TXD7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

293826:AMET RS07695
gene id: 293826:AMET_RS07695
uniprot id: A6TNH5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS01760
gene id: 293826:AMET_RS01760
uniprot id: A6TK55
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

293826:AMET RS05995
gene id: 293826:AMET_RS05995
uniprot id: A6TMK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

293826:AMET RS04005
gene id: 293826:AMET_RS04005
uniprot id: A6TLG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

293826:AMET RS22565
gene id: 293826:AMET_RS22565
uniprot id: A6TWM1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

293826:AMET RS22420
gene id: 293826:AMET_RS22420
uniprot id: A6TWJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

293826:AMET RS02535
gene id: 293826:AMET_RS02535
uniprot id: A6TKL3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

293826:AMET RS11655
gene id: 293826:AMET_RS11655
uniprot id: A6TQP4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

293826:AMET RS01560
gene id: 293826:AMET_RS01560
uniprot id: A6TK17
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS11080
gene id: 293826:AMET_RS11080
uniprot id: A6TQD4
names: Subunit
messages: Homodimer.

293826:AMET RS20780
gene id: 293826:AMET_RS20780
uniprot id: A6TVU5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

293826:AMET RS12365
gene id: 293826:AMET_RS12365
uniprot id: A6TR38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

293826:AMET RS20370
gene id: 293826:AMET_RS20370
uniprot id: A6TVL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

293826:AMET RS07850
gene id: 293826:AMET_RS07850
uniprot id: A6TNK3
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

293826:AMET RS15015
gene id: 293826:AMET_RS15015
uniprot id: A6TSM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

293826:AMET RS14760
gene id: 293826:AMET_RS14760
uniprot id: A6TSH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

293826:AMET RS14245
gene id: 293826:AMET_RS14245
uniprot id: A6TS72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

293826:AMET RS14980
gene id: 293826:AMET_RS14980
uniprot id: A6TSL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

293826:AMET RS01315
gene id: 293826:AMET_RS01315
uniprot id: A6TJW7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS14030
gene id: 293826:AMET_RS14030
uniprot id: A6TM42
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

293826:AMET RS23760
gene id: 293826:AMET_RS23760
uniprot id: A6TXA6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS20660
gene id: 293826:AMET_RS20660
uniprot id: A6TVS1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

293826:AMET RS14745
gene id: 293826:AMET_RS14745
uniprot id: A6TSH1
names: Similarity
messages: Belongs to the UPF0178 family.

293826:AMET RS00885
gene id: 293826:AMET_RS00885
uniprot id: A6TJN2
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS12495
gene id: 293826:AMET_RS12495
uniprot id: A6TR64
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

293826:AMET RS05355
gene id: 293826:AMET_RS05355
uniprot id: A6TM79
names: Similarity
messages: Belongs to the peptidase M29 family.

293826:AMET RS06245
gene id: 293826:AMET_RS06245
uniprot id: A6TMQ4
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

293826:AMET RS01000
gene id: 293826:AMET_RS01000
uniprot id: A6TJQ6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

293826:AMET RS04680
gene id: 293826:AMET_RS04680
uniprot id: A6TLV4
names: Similarity
messages: Belongs to the HypE family.

293826:AMET RS02875
gene id: 293826:AMET_RS02875
uniprot id: A6TKT0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

293826:AMET RS22200
gene id: 293826:AMET_RS22200
uniprot id: A6TWE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

293826:AMET RS23525
gene id: 293826:AMET_RS23525
uniprot id: A6TX58
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

293826:AMET RS10835
gene id: 293826:AMET_RS10835
uniprot id: A6TQ85
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

293826:AMET RS17760
gene id: 293826:AMET_RS17760
uniprot id: A6TU69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

293826:AMET RS17105
gene id: 293826:AMET_RS17105
uniprot id: A6TTU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

293826:AMET RS03830
gene id: 293826:AMET_RS03830
uniprot id: A6TLD2
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

293826:AMET RS16805
gene id: 293826:AMET_RS16805
uniprot id: A6TTN0
names: Similarity
messages: Belongs to the UPF0371 family.

293826:AMET RS23200
gene id: 293826:AMET_RS23200
uniprot id: A6TWZ6
names: Similarity
messages: Belongs to the AOR/FOR family.

293826:AMET RS18535
gene id: 293826:AMET_RS18535
uniprot id: A6TUM1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

293826:AMET RS22445
gene id: 293826:AMET_RS22445
uniprot id: A6TWJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

293826:AMET RS23085
gene id: 293826:AMET_RS23085
uniprot id: A6TWX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

293826:AMET RS13020
gene id: 293826:AMET_RS13020
uniprot id: A6TRH4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

293826:AMET RS11380
gene id: 293826:AMET_RS11380
uniprot id: A6TQJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

293826:AMET RS05040
gene id: 293826:AMET_RS05040
uniprot id: A6TM19
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

293826:AMET RS00385
gene id: 293826:AMET_RS00385
uniprot id: A6TJD6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

293826:AMET RS07515
gene id: 293826:AMET_RS07515
uniprot id: A6TNE3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS09990
gene id: 293826:AMET_RS09990
uniprot id: A6TPR7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

293826:AMET RS13165
gene id: 293826:AMET_RS13165
uniprot id: A6TRK3
names: Similarity
messages: Belongs to the ribF family.

293826:AMET RS04565
gene id: 293826:AMET_RS04565
uniprot id: A6TLS7
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

293826:AMET RS14520
gene id: 293826:AMET_RS14520
uniprot id: A6TSC8
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

293826:AMET RS00220
gene id: 293826:AMET_RS00220
uniprot id: A6TJB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

293826:AMET RS13440
gene id: 293826:AMET_RS13440
uniprot id: A6TRQ8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

293826:AMET RS14680
gene id: 293826:AMET_RS14680
uniprot id: A6TSF9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS06185
gene id: 293826:AMET_RS06185
uniprot id: A6TMP2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

293826:AMET RS16630
gene id: 293826:AMET_RS16630
uniprot id: A6TTJ5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS20775
gene id: 293826:AMET_RS20775
uniprot id: A6TVU4
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.

293826:AMET RS18235
gene id: 293826:AMET_RS18235
uniprot id: A6TUG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

293826:AMET RS00280
gene id: 293826:AMET_RS00280
uniprot id: A6TJB5
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS20640
gene id: 293826:AMET_RS20640
uniprot id: A6TVR7
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS18660
gene id: 293826:AMET_RS18660
uniprot id: A6TUP5
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

293826:AMET RS22375
gene id: 293826:AMET_RS22375
uniprot id: A6TWI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

293826:AMET RS00860
gene id: 293826:AMET_RS00860
uniprot id: A6TJM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

293826:AMET RS04690
gene id: 293826:AMET_RS04690
uniprot id: A6TLV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane

293826:AMET RS17305
gene id: 293826:AMET_RS17305
uniprot id: A6TTY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

293826:AMET RS07765
gene id: 293826:AMET_RS07765
uniprot id: A6TNI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

293826:AMET RS04915
gene id: 293826:AMET_RS04915
uniprot id: A6TLZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

293826:AMET RS17295
gene id: 293826:AMET_RS17295
uniprot id: A6TTX8
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

293826:AMET RS07720
gene id: 293826:AMET_RS07720
uniprot id: A6TNI0
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS11015
gene id: 293826:AMET_RS11015
uniprot id: A6TQC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

293826:AMET RS14880
gene id: 293826:AMET_RS14880
uniprot id: A6TSJ6
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

293826:AMET RS13350
gene id: 293826:AMET_RS13350
uniprot id: A6TRP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

293826:AMET RS05580
gene id: 293826:AMET_RS05580
uniprot id: A6TMC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS05625
gene id: 293826:AMET_RS05625
uniprot id: A6TMD4
names: Similarity
messages: Belongs to the type IA topoisomerase family.

293826:AMET RS15915
gene id: 293826:AMET_RS15915
uniprot id: A6TT50
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

293826:AMET RS00010
gene id: 293826:AMET_RS00010
uniprot id: A6TJ77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

293826:AMET RS00850
gene id: 293826:AMET_RS00850
uniprot id: A6TJM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

293826:AMET RS22915
gene id: 293826:AMET_RS22915
uniprot id: A6TWT8
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

293826:AMET RS01810
gene id: 293826:AMET_RS01810
uniprot id: A6TK65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

293826:AMET RS17490
gene id: 293826:AMET_RS17490
uniprot id: A6TU17
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS03600
gene id: 293826:AMET_RS03600
uniprot id: A6TL82
names: Similarity
messages: Belongs to the FlgM family.

293826:AMET RS16075
gene id: 293826:AMET_RS16075
uniprot id: A6TT88
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

293826:AMET RS00145
gene id: 293826:AMET_RS00145
uniprot id: A6TJ99
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

293826:AMET RS10275
gene id: 293826:AMET_RS10275
uniprot id: A6TPX1
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

293826:AMET RS03185
gene id: 293826:AMET_RS03185
uniprot id: A6TKZ5
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

293826:AMET RS13160
gene id: 293826:AMET_RS13160
uniprot id: A6TRK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

293826:AMET RS20715
gene id: 293826:AMET_RS20715
uniprot id: A6TVT2
names: Similarity
messages: Belongs to the helicase family. RAD3/XPD subfamily.

293826:AMET RS11595
gene id: 293826:AMET_RS11595
uniprot id: A6TQN2
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

293826:AMET RS14665
gene id: 293826:AMET_RS14665
uniprot id: A6TSF6
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

293826:AMET RS13445
gene id: 293826:AMET_RS13445
uniprot id: A6TRQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

293826:AMET RS21110
gene id: 293826:AMET_RS21110
uniprot id: A6TW06
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

293826:AMET RS11305
gene id: 293826:AMET_RS11305
uniprot id: A6TQH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

293826:AMET RS23125
gene id: 293826:AMET_RS23125
uniprot id: A6TWY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS11585
gene id: 293826:AMET_RS11585
uniprot id: A6TQM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

293826:AMET RS17715
gene id: 293826:AMET_RS17715
uniprot id: A6TU60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

293826:AMET RS15575
gene id: 293826:AMET_RS15575
uniprot id: A6TSY7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

293826:AMET RS19160
gene id: 293826:AMET_RS19160
uniprot id: A6TUY1
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

293826:AMET RS01665
gene id: 293826:AMET_RS01665
uniprot id: A6TK36
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

293826:AMET RS06700
gene id: 293826:AMET_RS06700
uniprot id: A6TMY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

293826:AMET RS04435
gene id: 293826:AMET_RS04435
uniprot id: A6TLQ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

293826:AMET RS13560
gene id: 293826:AMET_RS13560
uniprot id: A6TRS9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

293826:AMET RS12110
gene id: 293826:AMET_RS12110
uniprot id: A6TQY7
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

293826:AMET RS03695
gene id: 293826:AMET_RS03695
uniprot id: A6TLA3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

293826:AMET RS18275
gene id: 293826:AMET_RS18275
uniprot id: A6TUH0
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS00750
gene id: 293826:AMET_RS00750
uniprot id: A6TJK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

293826:AMET RS19410
gene id: 293826:AMET_RS19410
uniprot id: A6TV23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

293826:AMET RS11665
gene id: 293826:AMET_RS11665
uniprot id: A6TQP6
names: Similarity
messages: Belongs to the UPF0751 family.

293826:AMET RS05160
gene id: 293826:AMET_RS05160
uniprot id: A6TM42
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

293826:AMET RS15190
gene id: 293826:AMET_RS15190
uniprot id: A6TSQ9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS20790
gene id: 293826:AMET_RS20790
uniprot id: A6TVU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

293826:AMET RS13460
gene id: 293826:AMET_RS13460
uniprot id: A6TRR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

293826:AMET RS13345
gene id: 293826:AMET_RS13345
uniprot id: A6TRN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

293826:AMET RS13570
gene id: 293826:AMET_RS13570
uniprot id: A6TRT1
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

293826:AMET RS22750
gene id: 293826:AMET_RS22750
uniprot id: A6TWQ6
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

293826:AMET RS02435
gene id: 293826:AMET_RS02435
uniprot id: A6TKJ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

293826:AMET RS01785
gene id: 293826:AMET_RS01785
uniprot id: A6TK60
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

293826:AMET RS07635
gene id: 293826:AMET_RS07635
uniprot id: A6TNG5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

293826:AMET RS22140
gene id: 293826:AMET_RS22140
uniprot id: A6TWD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

293826:AMET RS16050
gene id: 293826:AMET_RS16050
uniprot id: A6TT81
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS14205
gene id: 293826:AMET_RS14205
uniprot id: A6TS63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

293826:AMET RS01200
gene id: 293826:AMET_RS01200
uniprot id: A6TJU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxA family. PdxA2 subfamily.
messages: Catalyzes the NAD-dependent oxidation and subsequent decarboxylation of D-threonate 4-phosphate to produce dihydroxyacetone phosphate (DHAP).
messages: Homodimer.

293826:AMET RS15700
gene id: 293826:AMET_RS15700
uniprot id: A6TT08
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS20285
gene id: 293826:AMET_RS20285
uniprot id: A6TVJ5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

293826:AMET RS17055
gene id: 293826:AMET_RS17055
uniprot id: A6TTT0
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

293826:AMET RS26635
gene id: 293826:AMET_RS26635
uniprot id: A6TU32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

293826:AMET RS23540
gene id: 293826:AMET_RS23540
uniprot id: A6TX61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

293826:AMET RS01300
gene id: 293826:AMET_RS01300
uniprot id: A6TJW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

293826:AMET RS16650
gene id: 293826:AMET_RS16650
uniprot id: A6TTJ9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

293826:AMET RS04940
gene id: 293826:AMET_RS04940
uniprot id: A6TLZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

293826:AMET RS12395
gene id: 293826:AMET_RS12395
uniprot id: A6TR44
names: Similarity
messages: Belongs to the TlyA family.

293826:AMET RS23735
gene id: 293826:AMET_RS23735
uniprot id: A6TXA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS04120
gene id: 293826:AMET_RS04120
uniprot id: A6TLJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

293826:AMET RS20085
gene id: 293826:AMET_RS20085
uniprot id: A6TVF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

293826:AMET RS01740
gene id: 293826:AMET_RS01740
uniprot id: A6TK51
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

293826:AMET RS01165
gene id: 293826:AMET_RS01165
uniprot id: A6TJT8
names: Similarity
messages: Belongs to the DprA/Smf family.

293826:AMET RS07835
gene id: 293826:AMET_RS07835
uniprot id: A6TNK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

293826:AMET RS22480
gene id: 293826:AMET_RS22480
uniprot id: A6TWK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

293826:AMET RS04590
gene id: 293826:AMET_RS04590
uniprot id: A6TLT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

293826:AMET RS15160
gene id: 293826:AMET_RS15160
uniprot id: A6TSQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

293826:AMET RS02870
gene id: 293826:AMET_RS02870
uniprot id: A6TKS9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

293826:AMET RS18595
gene id: 293826:AMET_RS18595
uniprot id: A6TUN2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

293826:AMET RS14885
gene id: 293826:AMET_RS14885
uniprot id: A6TSJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

293826:AMET RS04705
gene id: 293826:AMET_RS04705
uniprot id: A6TLV9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

293826:AMET RS22985
gene id: 293826:AMET_RS22985
uniprot id: A6TWV2
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

293826:AMET RS00390
gene id: 293826:AMET_RS00390
uniprot id: A6TJD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

293826:AMET RS16585
gene id: 293826:AMET_RS16585
uniprot id: A6TTI6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

293826:AMET RS22340
gene id: 293826:AMET_RS22340
uniprot id: A6TWH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

293826:AMET RS09470
gene id: 293826:AMET_RS09470
uniprot id: A6TPG1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS14775
gene id: 293826:AMET_RS14775
uniprot id: A6TSH7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS10715
gene id: 293826:AMET_RS10715
uniprot id: A6TQ61
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

293826:AMET RS23455
gene id: 293826:AMET_RS23455
uniprot id: A6TX43
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

293826:AMET RS14195
gene id: 293826:AMET_RS14195
uniprot id: A6TS61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

293826:AMET RS15455
gene id: 293826:AMET_RS15455
uniprot id: A6TSW2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS03480
gene id: 293826:AMET_RS03480
uniprot id: A6TL56
names: Similarity
messages: Belongs to the AOR/FOR family.

293826:AMET RS07975
gene id: 293826:AMET_RS07975
uniprot id: A6TNM5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

293826:AMET RS22630
gene id: 293826:AMET_RS22630
uniprot id: A6TWN1
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

293826:AMET RS15370
gene id: 293826:AMET_RS15370
uniprot id: A6TSU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

293826:AMET RS04305
gene id: 293826:AMET_RS04305
uniprot id: A6TLM6
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

293826:AMET RS06800
gene id: 293826:AMET_RS06800
uniprot id: A6TN09
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS10435
gene id: 293826:AMET_RS10435
uniprot id: A6TM42
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

293826:AMET RS22295
gene id: 293826:AMET_RS22295
uniprot id: A6TWG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

293826:AMET RS14085
gene id: 293826:AMET_RS14085
uniprot id: A6TS39
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

293826:AMET RS16675
gene id: 293826:AMET_RS16675
uniprot id: A6TTK4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

293826:AMET RS06850
gene id: 293826:AMET_RS06850
uniprot id: A6TN20
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

293826:AMET RS13610
gene id: 293826:AMET_RS13610
uniprot id: A6TRT9
names: Similarity
messages: Belongs to the fabD family.

293826:AMET RS17265
gene id: 293826:AMET_RS17265
uniprot id: A6TTX2
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

293826:AMET RS17755
gene id: 293826:AMET_RS17755
uniprot id: A6TU68
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

293826:AMET RS12920
gene id: 293826:AMET_RS12920
uniprot id: A6TRF4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

293826:AMET RS00040
gene id: 293826:AMET_RS00040
uniprot id: A6TJ83
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

293826:AMET RS13765
gene id: 293826:AMET_RS13765
uniprot id: A6TRW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

293826:AMET RS16995
gene id: 293826:AMET_RS16995
uniprot id: A6TTR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

293826:AMET RS06675
gene id: 293826:AMET_RS06675
uniprot id: A6TMY4
names: Similarity
messages: Belongs to the CapA family.

293826:AMET RS00275
gene id: 293826:AMET_RS00275
uniprot id: A6TJB4
names: Similarity
messages: Belongs to the peptidase M20A family.

293826:AMET RS17610
gene id: 293826:AMET_RS17610
uniprot id: A6TU42
names: Similarity
messages: Belongs to the BMP lipoprotein family.

293826:AMET RS26630
gene id: 293826:AMET_RS26630
uniprot id: A6TTX7
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

293826:AMET RS01775
gene id: 293826:AMET_RS01775
uniprot id: A6TK58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

293826:AMET RS20060
gene id: 293826:AMET_RS20060
uniprot id: A6TVF0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS06370
gene id: 293826:AMET_RS06370
uniprot id: A6TMS6
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS14605
gene id: 293826:AMET_RS14605
uniprot id: A6TSE5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

293826:AMET RS08980
gene id: 293826:AMET_RS08980
uniprot id: A6TP54
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

293826:AMET RS18705
gene id: 293826:AMET_RS18705
uniprot id: A6TUQ4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS02345
gene id: 293826:AMET_RS02345
uniprot id: A6TKH7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

293826:AMET RS20065
gene id: 293826:AMET_RS20065
uniprot id: A6TVF1
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

293826:AMET RS12370
gene id: 293826:AMET_RS12370
uniprot id: A6TR39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

293826:AMET RS16715
gene id: 293826:AMET_RS16715
uniprot id: A6TTL2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

293826:AMET RS18215
gene id: 293826:AMET_RS18215
uniprot id: A6TUF8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

293826:AMET RS06975
gene id: 293826:AMET_RS06975
uniprot id: A6TN47
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS20635
gene id: 293826:AMET_RS20635
uniprot id: A6TVR6
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS20415
gene id: 293826:AMET_RS20415
uniprot id: A6TVM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

293826:AMET RS03220
gene id: 293826:AMET_RS03220
uniprot id: A6TL03
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

293826:AMET RS05610
gene id: 293826:AMET_RS05610
uniprot id: A6TMD1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS17875
gene id: 293826:AMET_RS17875
uniprot id: A6TU91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

293826:AMET RS06050
gene id: 293826:AMET_RS06050
uniprot id: A6TML7
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

293826:AMET RS13810
gene id: 293826:AMET_RS13810
uniprot id: A6TRX8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

293826:AMET RS13775
gene id: 293826:AMET_RS13775
uniprot id: A6TRX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

293826:AMET RS22800
gene id: 293826:AMET_RS22800
uniprot id: A6TWR5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

293826:AMET RS22230
gene id: 293826:AMET_RS22230
uniprot id: A6TWF3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

293826:AMET RS14355
gene id: 293826:AMET_RS14355
uniprot id: A6TS95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS09910
gene id: 293826:AMET_RS09910
uniprot id: A6TPQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS15200
gene id: 293826:AMET_RS15200
uniprot id: A6TSR1
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

293826:AMET RS17900
gene id: 293826:AMET_RS17900
uniprot id: A6TU96
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

293826:AMET RS20755
gene id: 293826:AMET_RS20755
uniprot id: A6TVU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

293826:AMET RS12060
gene id: 293826:AMET_RS12060
uniprot id: A6TQX6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

293826:AMET RS12300
gene id: 293826:AMET_RS12300
uniprot id: A6TR25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

293826:AMET RS06280
gene id: 293826:AMET_RS06280
uniprot id: A6TMR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

293826:AMET RS22555
gene id: 293826:AMET_RS22555
uniprot id: A6TWL9
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

293826:AMET RS11390
gene id: 293826:AMET_RS11390
uniprot id: A6TQJ4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

293826:AMET RS03355
gene id: 293826:AMET_RS03355
uniprot id: A6TL30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS18145
gene id: 293826:AMET_RS18145
uniprot id: A6TUE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

293826:AMET RS16990
gene id: 293826:AMET_RS16990
uniprot id: A6TTR7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

293826:AMET RS03240
gene id: 293826:AMET_RS03240
uniprot id: A6TL07
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

293826:AMET RS23150
gene id: 293826:AMET_RS23150
uniprot id: A6TWY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

293826:AMET RS00295
gene id: 293826:AMET_RS00295
uniprot id: A6TJB8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

293826:AMET RS00225
gene id: 293826:AMET_RS00225
uniprot id: A6TJB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

293826:AMET RS00895
gene id: 293826:AMET_RS00895
uniprot id: A6TJN4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

293826:AMET RS18520
gene id: 293826:AMET_RS18520
uniprot id: A6TUL8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

293826:AMET RS20960
gene id: 293826:AMET_RS20960
uniprot id: A6TVX9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

293826:AMET RS23620
gene id: 293826:AMET_RS23620
uniprot id: A6TX78
names: Similarity
messages: Belongs to the EamA transporter family.

293826:AMET RS06195
gene id: 293826:AMET_RS06195
uniprot id: A6TMP4
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS11460
gene id: 293826:AMET_RS11460
uniprot id: A6TQK8
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

293826:AMET RS02580
gene id: 293826:AMET_RS02580
uniprot id: A6TKM2
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

293826:AMET RS20070
gene id: 293826:AMET_RS20070
uniprot id: A6TVF3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

293826:AMET RS22560
gene id: 293826:AMET_RS22560
uniprot id: A6TWM0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

293826:AMET RS23070
gene id: 293826:AMET_RS23070
uniprot id: A6TWX0
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS17650
gene id: 293826:AMET_RS17650
uniprot id: A6TU48
names: Similarity
messages: Belongs to the thioredoxin family.

293826:AMET RS05080
gene id: 293826:AMET_RS05080
uniprot id: A6TM28
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

293826:AMET RS04990
gene id: 293826:AMET_RS04990
uniprot id: A6TM08
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

293826:AMET RS13505
gene id: 293826:AMET_RS13505
uniprot id: A6TRR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

293826:AMET RS08325
gene id: 293826:AMET_RS08325
uniprot id: A6TNU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

293826:AMET RS11960
gene id: 293826:AMET_RS11960
uniprot id: A6TQV6
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

293826:AMET RS10985
gene id: 293826:AMET_RS10985
uniprot id: A6TQB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

293826:AMET RS08225
gene id: 293826:AMET_RS08225
uniprot id: A6TNS2
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

293826:AMET RS22715
gene id: 293826:AMET_RS22715
uniprot id: A6TWP8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

293826:AMET RS15665
gene id: 293826:AMET_RS15665
uniprot id: A6TT02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

293826:AMET RS20680
gene id: 293826:AMET_RS20680
uniprot id: A6TVS5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

293826:AMET RS18870
gene id: 293826:AMET_RS18870
uniprot id: A6TUT6
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

293826:AMET RS02750
gene id: 293826:AMET_RS02750
uniprot id: A6TKQ5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS18765
gene id: 293826:AMET_RS18765
uniprot id: A6TUR6
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

293826:AMET RS15205
gene id: 293826:AMET_RS15205
uniprot id: A6TSR2
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

293826:AMET RS14855
gene id: 293826:AMET_RS14855
uniprot id: A6TSJ1
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

293826:AMET RS24565
gene id: 293826:AMET_RS24565
uniprot id: A6TVC1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

293826:AMET RS22325
gene id: 293826:AMET_RS22325
uniprot id: A6TWH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

293826:AMET RS16250
gene id: 293826:AMET_RS16250
uniprot id: A6TTB9
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS06630
gene id: 293826:AMET_RS06630
uniprot id: A6TMX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

293826:AMET RS08170
gene id: 293826:AMET_RS08170
uniprot id: A6TNR1
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS18795
gene id: 293826:AMET_RS18795
uniprot id: A6TUS1
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

293826:AMET RS08085
gene id: 293826:AMET_RS08085
uniprot id: A6TNP4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

293826:AMET RS06335
gene id: 293826:AMET_RS06335
uniprot id: A6TMS0
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

293826:AMET RS06790
gene id: 293826:AMET_RS06790
uniprot id: A6TN07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

293826:AMET RS22240
gene id: 293826:AMET_RS22240
uniprot id: A6TWF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

293826:AMET RS10060
gene id: 293826:AMET_RS10060
uniprot id: A6TPT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS08030
gene id: 293826:AMET_RS08030
uniprot id: A6TNN6
names: Subcellular Location Annotation
messages: Cytoplasm

293826:AMET RS22425
gene id: 293826:AMET_RS22425
uniprot id: A6TWJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

293826:AMET RS01190
gene id: 293826:AMET_RS01190
uniprot id: A6TJU3
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

293826:AMET RS11320
gene id: 293826:AMET_RS11320
uniprot id: A6TQI0
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

293826:AMET RS06820
gene id: 293826:AMET_RS06820
uniprot id: A6TN13
names: Similarity
messages: Belongs to the UPF0045 family.

293826:AMET RS05015
gene id: 293826:AMET_RS05015
uniprot id: A6TM13
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS11310
gene id: 293826:AMET_RS11310
uniprot id: A6TQH8
names: Similarity
messages: Belongs to the UPF0758 family.

293826:AMET RS13550
gene id: 293826:AMET_RS13550
uniprot id: A6TRS7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

293826:AMET RS22310
gene id: 293826:AMET_RS22310
uniprot id: A6TWG9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

293826:AMET RS15125
gene id: 293826:AMET_RS15125
uniprot id: A6TSP6
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

293826:AMET RS09480
gene id: 293826:AMET_RS09480
uniprot id: A6TPG3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS05600
gene id: 293826:AMET_RS05600
uniprot id: A6TMC9
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS05640
gene id: 293826:AMET_RS05640
uniprot id: A6TMD7
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

293826:AMET RS13290
gene id: 293826:AMET_RS13290
uniprot id: A6TRM8
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

293826:AMET RS20080
gene id: 293826:AMET_RS20080
uniprot id: A6TVF5
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

293826:AMET RS00365
gene id: 293826:AMET_RS00365
uniprot id: A6TJD2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

293826:AMET RS02930
gene id: 293826:AMET_RS02930
uniprot id: A6TKU2
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

293826:AMET RS06925
gene id: 293826:AMET_RS06925
uniprot id: A6TN36
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS17425
gene id: 293826:AMET_RS17425
uniprot id: A6TU05
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

293826:AMET RS12175
gene id: 293826:AMET_RS12175
uniprot id: A6TR01
names: Similarity
messages: Belongs to the SfsA family.

293826:AMET RS12515
gene id: 293826:AMET_RS12515
uniprot id: A6TR68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

293826:AMET RS01470
gene id: 293826:AMET_RS01470
uniprot id: A6TJZ9
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

293826:AMET RS03625
gene id: 293826:AMET_RS03625
uniprot id: A6TL87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

293826:AMET RS01855
gene id: 293826:AMET_RS01855
uniprot id: A6TK74
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

293826:AMET RS06690
gene id: 293826:AMET_RS06690
uniprot id: A6TMY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

293826:AMET RS18040
gene id: 293826:AMET_RS18040
uniprot id: A6TUC4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

293826:AMET RS13535
gene id: 293826:AMET_RS13535
uniprot id: A6TRS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

293826:AMET RS14225
gene id: 293826:AMET_RS14225
uniprot id: A6TS67
names: Similarity
messages: Belongs to the transpeptidase family.

293826:AMET RS07655
gene id: 293826:AMET_RS07655
uniprot id: A6TNG7
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

293826:AMET RS03360
gene id: 293826:AMET_RS03360
uniprot id: A6TL31
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

293826:AMET RS00290
gene id: 293826:AMET_RS00290
uniprot id: A6TJB7
names: Similarity
messages: Belongs to the peptidase M20A family.

293826:AMET RS19115
gene id: 293826:AMET_RS19115
uniprot id: A6TUX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS06450
gene id: 293826:AMET_RS06450
uniprot id: A6TMU1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

293826:AMET RS02230
gene id: 293826:AMET_RS02230
uniprot id: A6TKF3
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

293826:AMET RS14235
gene id: 293826:AMET_RS14235
uniprot id: A6TS69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

293826:AMET RS17445
gene id: 293826:AMET_RS17445
uniprot id: A6TU09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

293826:AMET RS20665
gene id: 293826:AMET_RS20665
uniprot id: A6TVS2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS18820
gene id: 293826:AMET_RS18820
uniprot id: A6TUS6
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

293826:AMET RS13180
gene id: 293826:AMET_RS13180
uniprot id: A6TRK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

293826:AMET RS12045
gene id: 293826:AMET_RS12045
uniprot id: A6TQX3
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS12475
gene id: 293826:AMET_RS12475
uniprot id: A6TR60
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

293826:AMET RS22530
gene id: 293826:AMET_RS22530
uniprot id: A6TWL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

293826:AMET RS08080
gene id: 293826:AMET_RS08080
uniprot id: A6TNP3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

293826:AMET RS05330
gene id: 293826:AMET_RS05330
uniprot id: A6TM74
names: Similarity
messages: Belongs to the TrpC family.

293826:AMET RS14455
gene id: 293826:AMET_RS14455
uniprot id: A6TSB5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

293826:AMET RS18375
gene id: 293826:AMET_RS18375
uniprot id: A6TUI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

293826:AMET RS20605
gene id: 293826:AMET_RS20605
uniprot id: A6TVR0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

293826:AMET RS16595
gene id: 293826:AMET_RS16595
uniprot id: A6TTI8
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS09935
gene id: 293826:AMET_RS09935
uniprot id: A6TPQ6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

293826:AMET RS13485
gene id: 293826:AMET_RS13485
uniprot id: A6TRR5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS06735
gene id: 293826:AMET_RS06735
uniprot id: A6TMZ6
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

293826:AMET RS06065
gene id: 293826:AMET_RS06065
uniprot id: A6TMM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

293826:AMET RS07840
gene id: 293826:AMET_RS07840
uniprot id: A6TNK1
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

293826:AMET RS11555
gene id: 293826:AMET_RS11555
uniprot id: A6TQM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

293826:AMET RS02730
gene id: 293826:AMET_RS02730
uniprot id: A6TKQ1
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

293826:AMET RS16385
gene id: 293826:AMET_RS16385
uniprot id: A6TTE4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

293826:AMET RS09985
gene id: 293826:AMET_RS09985
uniprot id: A6TPR6
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

293826:AMET RS04635
gene id: 293826:AMET_RS04635
uniprot id: A6TLU4
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

293826:AMET RS14080
gene id: 293826:AMET_RS14080
uniprot id: A6TS38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

293826:AMET RS00830
gene id: 293826:AMET_RS00830
uniprot id: A6TJM1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

293826:AMET RS16345
gene id: 293826:AMET_RS16345
uniprot id: A6TTD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

293826:AMET RS23480
gene id: 293826:AMET_RS23480
uniprot id: A6TX48
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

293826:AMET RS20760
gene id: 293826:AMET_RS20760
uniprot id: A6TVU1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

293826:AMET RS17705
gene id: 293826:AMET_RS17705
uniprot id: A6TU58
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

293826:AMET RS20280
gene id: 293826:AMET_RS20280
uniprot id: A6TVJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

293826:AMET RS03935
gene id: 293826:AMET_RS03935
uniprot id: A6TLF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

293826:AMET RS13930
gene id: 293826:AMET_RS13930
uniprot id: A6TS03
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

293826:AMET RS16685
gene id: 293826:AMET_RS16685
uniprot id: A6TTK6
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS02835
gene id: 293826:AMET_RS02835
uniprot id: A6TKS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

293826:AMET RS12415
gene id: 293826:AMET_RS12415
uniprot id: A6TR48
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS04185
gene id: 293826:AMET_RS04185
uniprot id: A6TLK4
names: Similarity
messages: Belongs to the HsdR family.

293826:AMET RS13565
gene id: 293826:AMET_RS13565
uniprot id: A6TRT0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

293826:AMET RS14690
gene id: 293826:AMET_RS14690
uniprot id: A6TSG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

293826:AMET RS04950
gene id: 293826:AMET_RS04950
uniprot id: A6TM00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

293826:AMET RS10735
gene id: 293826:AMET_RS10735
uniprot id: A6TQ65
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

293826:AMET RS23115
gene id: 293826:AMET_RS23115
uniprot id: A6TWX9
names: Similarity
messages: Belongs to the EamA transporter family.

293826:AMET RS20925
gene id: 293826:AMET_RS20925
uniprot id: A6TVX2
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS03510
gene id: 293826:AMET_RS03510
uniprot id: A6TL62
names: Similarity
messages: Belongs to the UPF0473 family.

293826:AMET RS06795
gene id: 293826:AMET_RS06795
uniprot id: A6TN08
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

293826:AMET RS23145
gene id: 293826:AMET_RS23145
uniprot id: A6TWY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

293826:AMET RS21690
gene id: 293826:AMET_RS21690
uniprot id: A6TW43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

293826:AMET RS16405
gene id: 293826:AMET_RS16405
uniprot id: A6TTE8
names: Similarity
messages: Belongs to the peptidase M24B family.

293826:AMET RS12955
gene id: 293826:AMET_RS12955
uniprot id: A6TRG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

293826:AMET RS20215
gene id: 293826:AMET_RS20215
uniprot id: A6TVI1
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS00320
gene id: 293826:AMET_RS00320
uniprot id: A6TJC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

293826:AMET RS14610
gene id: 293826:AMET_RS14610
uniprot id: A6TSE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

293826:AMET RS02585
gene id: 293826:AMET_RS02585
uniprot id: A6TKM3
names: Similarity
messages: Belongs to the GerABKA family.

293826:AMET RS19905
gene id: 293826:AMET_RS19905
uniprot id: A6TVC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

293826:AMET RS22210
gene id: 293826:AMET_RS22210
uniprot id: A6TWE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

293826:AMET RS11325
gene id: 293826:AMET_RS11325
uniprot id: A6TQI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

293826:AMET RS13945
gene id: 293826:AMET_RS13945
uniprot id: A6TS06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

293826:AMET RS17415
gene id: 293826:AMET_RS17415
uniprot id: A6TU03
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

293826:AMET RS05450
gene id: 293826:AMET_RS05450
uniprot id: A6TM98
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

293826:AMET RS17750
gene id: 293826:AMET_RS17750
uniprot id: A6TU67
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

293826:AMET RS12930
gene id: 293826:AMET_RS12930
uniprot id: A6TRF6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

293826:AMET RS11270
gene id: 293826:AMET_RS11270
uniprot id: A6TQH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

293826:AMET RS22270
gene id: 293826:AMET_RS22270
uniprot id: A6TWG1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

293826:AMET RS14135
gene id: 293826:AMET_RS14135
uniprot id: A6TS49
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

293826:AMET RS20390
gene id: 293826:AMET_RS20390
uniprot id: A6TVL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

293826:AMET RS16020
gene id: 293826:AMET_RS16020
uniprot id: A6TT75
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS20590
gene id: 293826:AMET_RS20590
uniprot id: A6TVQ7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

293826:AMET RS23465
gene id: 293826:AMET_RS23465
uniprot id: A6TX45
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

293826:AMET RS01745
gene id: 293826:AMET_RS01745
uniprot id: A6TK52
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

293826:AMET RS15705
gene id: 293826:AMET_RS15705
uniprot id: A6TT09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

293826:AMET RS02590
gene id: 293826:AMET_RS02590
uniprot id: A6TKM4
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

293826:AMET RS06045
gene id: 293826:AMET_RS06045
uniprot id: A6TML6
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

293826:AMET RS11275
gene id: 293826:AMET_RS11275
uniprot id: A6TQH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

293826:AMET RS22360
gene id: 293826:AMET_RS22360
uniprot id: A6TWH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

293826:AMET RS06655
gene id: 293826:AMET_RS06655
uniprot id: A6TMY0
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

293826:AMET RS13330
gene id: 293826:AMET_RS13330
uniprot id: A6TRN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

293826:AMET RS17345
gene id: 293826:AMET_RS17345
uniprot id: A6TTY9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

293826:AMET RS14140
gene id: 293826:AMET_RS14140
uniprot id: A6TS50
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

293826:AMET RS18725
gene id: 293826:AMET_RS18725
uniprot id: A6TUQ8
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS20895
gene id: 293826:AMET_RS20895
uniprot id: A6TVW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

293826:AMET RS01835
gene id: 293826:AMET_RS01835
uniprot id: A6TK70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS05480
gene id: 293826:AMET_RS05480
uniprot id: A6TMA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

293826:AMET RS20975
gene id: 293826:AMET_RS20975
uniprot id: A6TVY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

293826:AMET RS20430
gene id: 293826:AMET_RS20430
uniprot id: A6TVM6
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS01650
gene id: 293826:AMET_RS01650
uniprot id: A6TK33
names: Similarity
messages: Belongs to the FBPase class 2 family.

293826:AMET RS03870
gene id: 293826:AMET_RS03870
uniprot id: A6TLE0
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

293826:AMET RS13755
gene id: 293826:AMET_RS13755
uniprot id: A6TRW7
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

293826:AMET RS08670
gene id: 293826:AMET_RS08670
uniprot id: A6TNZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

293826:AMET RS12180
gene id: 293826:AMET_RS12180
uniprot id: A6TR02
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

293826:AMET RS04920
gene id: 293826:AMET_RS04920
uniprot id: A6TLZ4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

293826:AMET RS13845
gene id: 293826:AMET_RS13845
uniprot id: A6TRY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

293826:AMET RS23325
gene id: 293826:AMET_RS23325
uniprot id: A6TX20
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS02440
gene id: 293826:AMET_RS02440
uniprot id: A6TKJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

293826:AMET RS23875
gene id: 293826:AMET_RS23875
uniprot id: A6TXC7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

293826:AMET RS14325
gene id: 293826:AMET_RS14325
uniprot id: A6TS89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS12165
gene id: 293826:AMET_RS12165
uniprot id: A6TQZ9
names: Similarity
messages: Belongs to the UPF0473 family.

293826:AMET RS10740
gene id: 293826:AMET_RS10740
uniprot id: A6TQ66
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS06645
gene id: 293826:AMET_RS06645
uniprot id: A6TMX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

293826:AMET RS08215
gene id: 293826:AMET_RS08215
uniprot id: A6TNS0
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

293826:AMET RS16610
gene id: 293826:AMET_RS16610
uniprot id: A6TTJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

293826:AMET RS22850
gene id: 293826:AMET_RS22850
uniprot id: A6TWS5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS04195
gene id: 293826:AMET_RS04195
uniprot id: A6TLK6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

293826:AMET RS12425
gene id: 293826:AMET_RS12425
uniprot id: A6TR50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

293826:AMET RS20670
gene id: 293826:AMET_RS20670
uniprot id: A6TVS3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

293826:AMET RS05420
gene id: 293826:AMET_RS05420
uniprot id: A6TM92
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS06775
gene id: 293826:AMET_RS06775
uniprot id: A6TN04
names: Similarity
messages: Belongs to the transposase 11 family.

293826:AMET RS14380
gene id: 293826:AMET_RS14380
uniprot id: A6TSA0
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS01620
gene id: 293826:AMET_RS01620
uniprot id: A6TK27
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS13375
gene id: 293826:AMET_RS13375
uniprot id: A6TRP5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

293826:AMET RS02570
gene id: 293826:AMET_RS02570
uniprot id: A6TKM0
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

293826:AMET RS26640
gene id: 293826:AMET_RS26640
uniprot id: A6TU33
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

293826:AMET RS14825
gene id: 293826:AMET_RS14825
uniprot id: A6TSI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

293826:AMET RS20315
gene id: 293826:AMET_RS20315
uniprot id: A6TVK2
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

293826:AMET RS13830
gene id: 293826:AMET_RS13830
uniprot id: A6TRY2
names: Subcellular Location Annotation
messages: Cytoplasm

293826:AMET RS20890
gene id: 293826:AMET_RS20890
uniprot id: A6TVW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

293826:AMET RS15630
gene id: 293826:AMET_RS15630
uniprot id: A6TSZ7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS15600
gene id: 293826:AMET_RS15600
uniprot id: A6TSZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

293826:AMET RS11485
gene id: 293826:AMET_RS11485
uniprot id: A6TQL3
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

293826:AMET RS14165
gene id: 293826:AMET_RS14165
uniprot id: A6TS55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

293826:AMET RS19620
gene id: 293826:AMET_RS19620
uniprot id: A6TV60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

293826:AMET RS06405
gene id: 293826:AMET_RS06405
uniprot id: A6TMT3
names: Subcellular Location Annotation
messages: Cytoplasm

293826:AMET RS14580
gene id: 293826:AMET_RS14580
uniprot id: A6TSE0
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

293826:AMET RS20405
gene id: 293826:AMET_RS20405
uniprot id: A6TVM0
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

293826:AMET RS12405
gene id: 293826:AMET_RS12405
uniprot id: A6TR46
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

293826:AMET RS10255
gene id: 293826:AMET_RS10255
uniprot id: A6TPW7
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS18230
gene id: 293826:AMET_RS18230
uniprot id: A6TUG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

293826:AMET RS07470
gene id: 293826:AMET_RS07470
uniprot id: A6TND6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

293826:AMET RS20990
gene id: 293826:AMET_RS20990
uniprot id: A6TVY5
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

293826:AMET RS22930
gene id: 293826:AMET_RS22930
uniprot id: A6TWU1
names: Similarity
messages: Belongs to the CdaR family.

293826:AMET RS05675
gene id: 293826:AMET_RS05675
uniprot id: A6TME4
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

293826:AMET RS15225
gene id: 293826:AMET_RS15225
uniprot id: A6TSR7
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

293826:AMET RS06565
gene id: 293826:AMET_RS06565
uniprot id: A6TMW2
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

293826:AMET RS13760
gene id: 293826:AMET_RS13760
uniprot id: A6TRW8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

293826:AMET RS03225
gene id: 293826:AMET_RS03225
uniprot id: A6TL04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

293826:AMET RS10170
gene id: 293826:AMET_RS10170
uniprot id: A6TPV1
names: Similarity
messages: Belongs to the transglycosylase Slt family.

293826:AMET RS15100
gene id: 293826:AMET_RS15100
uniprot id: A6TSP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

293826:AMET RS13295
gene id: 293826:AMET_RS13295
uniprot id: A6TRM9
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

293826:AMET RS22010
gene id: 293826:AMET_RS22010
uniprot id: A6TWB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

293826:AMET RS05275
gene id: 293826:AMET_RS05275
uniprot id: A6TM63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

293826:AMET RS00980
gene id: 293826:AMET_RS00980
uniprot id: A6TJQ2
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS03345
gene id: 293826:AMET_RS03345
uniprot id: A6TL28
names: Similarity
messages: Belongs to the proline racemase family.

293826:AMET RS11450
gene id: 293826:AMET_RS11450
uniprot id: A6TQK6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

293826:AMET RS01770
gene id: 293826:AMET_RS01770
uniprot id: A6TK57
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS09420
gene id: 293826:AMET_RS09420
uniprot id: A6TPF0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

293826:AMET RS17435
gene id: 293826:AMET_RS17435
uniprot id: A6TU07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

293826:AMET RS14890
gene id: 293826:AMET_RS14890
uniprot id: A6TSJ9
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

293826:AMET RS02905
gene id: 293826:AMET_RS02905
uniprot id: A6TKT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

293826:AMET RS12210
gene id: 293826:AMET_RS12210
uniprot id: A6TR08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

293826:AMET RS17275
gene id: 293826:AMET_RS17275
uniprot id: A6TTX4
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

293826:AMET RS11400
gene id: 293826:AMET_RS11400
uniprot id: A6TQJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

293826:AMET RS08220
gene id: 293826:AMET_RS08220
uniprot id: A6TNS1
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

293826:AMET RS24170
gene id: 293826:AMET_RS24170
uniprot id: A6TMD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

293826:AMET RS18455
gene id: 293826:AMET_RS18455
uniprot id: A6TUK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

293826:AMET RS09195
gene id: 293826:AMET_RS09195
uniprot id: A6TPA2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

293826:AMET RS01340
gene id: 293826:AMET_RS01340
uniprot id: A6TJX2
names: Subcellular Location Annotation
messages: Bacterial microcompartment

293826:AMET RS13200
gene id: 293826:AMET_RS13200
uniprot id: A6TRL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

293826:AMET RS20835
gene id: 293826:AMET_RS20835
uniprot id: A6TVV4
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS18440
gene id: 293826:AMET_RS18440
uniprot id: A6TUK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

293826:AMET RS08315
gene id: 293826:AMET_RS08315
uniprot id: A6TNU0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

293826:AMET RS23720
gene id: 293826:AMET_RS23720
uniprot id: A6TX97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

293826:AMET RS13515
gene id: 293826:AMET_RS13515
uniprot id: A6TRS0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

293826:AMET RS16615
gene id: 293826:AMET_RS16615
uniprot id: A6TTJ2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

293826:AMET RS20275
gene id: 293826:AMET_RS20275
uniprot id: A6TVJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

293826:AMET RS13250
gene id: 293826:AMET_RS13250
uniprot id: A6TRM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

293826:AMET RS20625
gene id: 293826:AMET_RS20625
uniprot id: A6TVR4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS07455
gene id: 293826:AMET_RS07455
uniprot id: A6TND2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS20025
gene id: 293826:AMET_RS20025
uniprot id: A6TM42
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

293826:AMET RS15360
gene id: 293826:AMET_RS15360
uniprot id: A6TSU4
names: Similarity
messages: Belongs to the transglycosylase Slt family.

293826:AMET RS13965
gene id: 293826:AMET_RS13965
uniprot id: A6TS10
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

293826:AMET RS14810
gene id: 293826:AMET_RS14810
uniprot id: A6TN04
names: Similarity
messages: Belongs to the transposase 11 family.

293826:AMET RS13645
gene id: 293826:AMET_RS13645
uniprot id: A6TRU6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

293826:AMET RS13780
gene id: 293826:AMET_RS13780
uniprot id: A6TRX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

293826:AMET RS21675
gene id: 293826:AMET_RS21675
uniprot id: A6TW40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

293826:AMET RS18565
gene id: 293826:AMET_RS18565
uniprot id: A6TUM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

293826:AMET RS20400
gene id: 293826:AMET_RS20400
uniprot id: A6TVL9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

293826:AMET RS13620
gene id: 293826:AMET_RS13620
uniprot id: A6TRU1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

293826:AMET RS00995
gene id: 293826:AMET_RS00995
uniprot id: A6TJQ5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

293826:AMET RS03790
gene id: 293826:AMET_RS03790
uniprot id: A6TLC3
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

293826:AMET RS03270
gene id: 293826:AMET_RS03270
uniprot id: A6TL13
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS17540
gene id: 293826:AMET_RS17540
uniprot id: A6TU28
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

293826:AMET RS00445
gene id: 293826:AMET_RS00445
uniprot id: A6TJE8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

293826:AMET RS23010
gene id: 293826:AMET_RS23010
uniprot id: A6TWV7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

293826:AMET RS22545
gene id: 293826:AMET_RS22545
uniprot id: A6TWL7
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

293826:AMET RS14215
gene id: 293826:AMET_RS14215
uniprot id: A6TS65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

293826:AMET RS15820
gene id: 293826:AMET_RS15820
uniprot id: A6TT31
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

293826:AMET RS15730
gene id: 293826:AMET_RS15730
uniprot id: A6TT14
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

293826:AMET RS08125
gene id: 293826:AMET_RS08125
uniprot id: A6TNQ2
names: Similarity
messages: Belongs to the DtxR/MntR family.

293826:AMET RS14905
gene id: 293826:AMET_RS14905
uniprot id: A6TSK2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

293826:AMET RS15695
gene id: 293826:AMET_RS15695
uniprot id: A6TT07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

293826:AMET RS01435
gene id: 293826:AMET_RS01435
uniprot id: A6TJZ2
names: Similarity
messages: Belongs to the polysaccharide synthase family.

293826:AMET RS13690
gene id: 293826:AMET_RS13690
uniprot id: A6TRV5
names: Similarity
messages: Belongs to the asp23 family.

293826:AMET RS15775
gene id: 293826:AMET_RS15775
uniprot id: A6TT23
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

293826:AMET RS15620
gene id: 293826:AMET_RS15620
uniprot id: A6TSZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS20265
gene id: 293826:AMET_RS20265
uniprot id: A6TVJ1
names: Similarity
messages: Belongs to the peptidase S41A family.

293826:AMET RS05615
gene id: 293826:AMET_RS05615
uniprot id: A6TMD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

293826:AMET RS10055
gene id: 293826:AMET_RS10055
uniprot id: A6TPT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS16705
gene id: 293826:AMET_RS16705
uniprot id: A6TTL0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

293826:AMET RS01700
gene id: 293826:AMET_RS01700
uniprot id: A6TK43
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

293826:AMET RS17865
gene id: 293826:AMET_RS17865
uniprot id: A6TU89
names: Similarity
messages: Belongs to the peptidase S16 family.

293826:AMET RS19710
gene id: 293826:AMET_RS19710
uniprot id: A6TV80
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS22535
gene id: 293826:AMET_RS22535
uniprot id: A6TWL5
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

293826:AMET RS16900
gene id: 293826:AMET_RS16900
uniprot id: A6TTP9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

293826:AMET RS13735
gene id: 293826:AMET_RS13735
uniprot id: A6TRW3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

293826:AMET RS16185
gene id: 293826:AMET_RS16185
uniprot id: A6TTA9
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

293826:AMET RS22195
gene id: 293826:AMET_RS22195
uniprot id: A6TWE6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

293826:AMET RS26975
gene id: 293826:AMET_RS26975
uniprot id: A6TUS4
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

293826:AMET RS13170
gene id: 293826:AMET_RS13170
uniprot id: A6TRK4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

293826:AMET RS22400
gene id: 293826:AMET_RS22400
uniprot id: A6TWI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

293826:AMET RS09820
gene id: 293826:AMET_RS09820
uniprot id: A6TPN2
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

293826:AMET RS22355
gene id: 293826:AMET_RS22355
uniprot id: A6TWH8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

293826:AMET RS13675
gene id: 293826:AMET_RS13675
uniprot id: A6TRV2
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

293826:AMET RS04485
gene id: 293826:AMET_RS04485
uniprot id: A6TLR2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

293826:AMET RS00535
gene id: 293826:AMET_RS00535
uniprot id: A6TJG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

293826:AMET RS20880
gene id: 293826:AMET_RS20880
uniprot id: A6TVW3
names: Similarity
messages: Belongs to the peptidase M29 family.

293826:AMET RS00425
gene id: 293826:AMET_RS00425
uniprot id: A6TJE4
names: Similarity
messages: Belongs to the CobH/CbiC family.

293826:AMET RS12770
gene id: 293826:AMET_RS12770
uniprot id: A6TRB9
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS22415
gene id: 293826:AMET_RS22415
uniprot id: A6TWJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

293826:AMET RS13450
gene id: 293826:AMET_RS13450
uniprot id: A6TRR0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

293826:AMET RS18430
gene id: 293826:AMET_RS18430
uniprot id: A6TUK0
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

293826:AMET RS12080
gene id: 293826:AMET_RS12080
uniprot id: A6TQY1
names: Similarity
messages: Belongs to the threonine aldolase family.

293826:AMET RS12375
gene id: 293826:AMET_RS12375
uniprot id: A6TR40
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

293826:AMET RS01920
gene id: 293826:AMET_RS01920
uniprot id: A6TK87
names: Similarity
messages: Belongs to the UDPGP type 2 family.

293826:AMET RS03895
gene id: 293826:AMET_RS03895
uniprot id: A6TLE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

293826:AMET RS16040
gene id: 293826:AMET_RS16040
uniprot id: A6TT79
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS03755
gene id: 293826:AMET_RS03755
uniprot id: A6TLB6
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

293826:AMET RS01655
gene id: 293826:AMET_RS01655
uniprot id: A6TK34
names: Similarity
messages: Belongs to the FBPase class 2 family.

293826:AMET RS23550
gene id: 293826:AMET_RS23550
uniprot id: A6TX64
names: Similarity
messages: Belongs to the EamA transporter family.

293826:AMET RS14990
gene id: 293826:AMET_RS14990
uniprot id: A6TSL9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

293826:AMET RS17520
gene id: 293826:AMET_RS17520
uniprot id: A6TU24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

293826:AMET RS17220
gene id: 293826:AMET_RS17220
uniprot id: A6TTW3
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

293826:AMET RS12490
gene id: 293826:AMET_RS12490
uniprot id: A6TR63
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

293826:AMET RS14765
gene id: 293826:AMET_RS14765
uniprot id: A6TSH5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

293826:AMET RS08165
gene id: 293826:AMET_RS08165
uniprot id: A6TNR0
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS13340
gene id: 293826:AMET_RS13340
uniprot id: A6TRN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

293826:AMET RS10830
gene id: 293826:AMET_RS10830
uniprot id: A6TQ84
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

293826:AMET RS14940
gene id: 293826:AMET_RS14940
uniprot id: A6TSK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts. FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Membrane raft

293826:AMET RS16580
gene id: 293826:AMET_RS16580
uniprot id: A6TTI5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

293826:AMET RS16780
gene id: 293826:AMET_RS16780
uniprot id: A6TTM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

293826:AMET RS18205
gene id: 293826:AMET_RS18205
uniprot id: A6TUF6
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS19980
gene id: 293826:AMET_RS19980
uniprot id: A6TVD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

293826:AMET RS03410
gene id: 293826:AMET_RS03410
uniprot id: A6TL41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

293826:AMET RS04945
gene id: 293826:AMET_RS04945
uniprot id: A6TLZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

293826:AMET RS07260
gene id: 293826:AMET_RS07260
uniprot id: A6TM42
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

293826:AMET RS23880
gene id: 293826:AMET_RS23880
uniprot id: A6TXC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

293826:AMET RS14360
gene id: 293826:AMET_RS14360
uniprot id: A6TS96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS24320
gene id: 293826:AMET_RS24320
uniprot id: A6TPV9
names: Similarity
messages: Belongs to the peptidase C40 family.

293826:AMET RS22665
gene id: 293826:AMET_RS22665
uniprot id: A6TWN8
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

293826:AMET RS22320
gene id: 293826:AMET_RS22320
uniprot id: A6TWH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

293826:AMET RS03470
gene id: 293826:AMET_RS03470
uniprot id: A6TL54
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

293826:AMET RS00870
gene id: 293826:AMET_RS00870
uniprot id: A6TJM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

293826:AMET RS04545
gene id: 293826:AMET_RS04545
uniprot id: A6TLS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

293826:AMET RS22060
gene id: 293826:AMET_RS22060
uniprot id: A6TWB9
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS05720
gene id: 293826:AMET_RS05720
uniprot id: A6TMF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS04050
gene id: 293826:AMET_RS04050
uniprot id: A6TLH7
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

293826:AMET RS20380
gene id: 293826:AMET_RS20380
uniprot id: A6TVL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Membrane

293826:AMET RS14870
gene id: 293826:AMET_RS14870
uniprot id: A6TSJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

293826:AMET RS03635
gene id: 293826:AMET_RS03635
uniprot id: A6TL89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

293826:AMET RS00625
gene id: 293826:AMET_RS00625
uniprot id: A6TJI4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS06040
gene id: 293826:AMET_RS06040
uniprot id: A6TML5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

293826:AMET RS16175
gene id: 293826:AMET_RS16175
uniprot id: A6TTA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS23260
gene id: 293826:AMET_RS23260
uniprot id: A6TX07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

293826:AMET RS13400
gene id: 293826:AMET_RS13400
uniprot id: A6TRQ0
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

293826:AMET RS18875
gene id: 293826:AMET_RS18875
uniprot id: A6TUT7
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

293826:AMET RS22115
gene id: 293826:AMET_RS22115
uniprot id: A6TWD0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

293826:AMET RS09300
gene id: 293826:AMET_RS09300
uniprot id: A6TPC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS17320
gene id: 293826:AMET_RS17320
uniprot id: A6TTY3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

293826:AMET RS04430
gene id: 293826:AMET_RS04430
uniprot id: A6TLQ3
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

293826:AMET RS01715
gene id: 293826:AMET_RS01715
uniprot id: A6TK46
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS17185
gene id: 293826:AMET_RS17185
uniprot id: A6TTV6
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

293826:AMET RS15045
gene id: 293826:AMET_RS15045
uniprot id: A6TSN0
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS08265
gene id: 293826:AMET_RS08265
uniprot id: A6TNT0
names: Function
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

293826:AMET RS01575
gene id: 293826:AMET_RS01575
uniprot id: A6TK20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

293826:AMET RS05740
gene id: 293826:AMET_RS05740
uniprot id: A6TMF6
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

293826:AMET RS01330
gene id: 293826:AMET_RS01330
uniprot id: A6TJX0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

293826:AMET RS19995
gene id: 293826:AMET_RS19995
uniprot id: A6TVD8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

293826:AMET RS18050
gene id: 293826:AMET_RS18050
uniprot id: A6TUC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

293826:AMET RS13555
gene id: 293826:AMET_RS13555
uniprot id: A6TRS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

293826:AMET RS18690
gene id: 293826:AMET_RS18690
uniprot id: A6TUQ1
names: Similarity
messages: Belongs to the aldose epimerase family.

293826:AMET RS22290
gene id: 293826:AMET_RS22290
uniprot id: A6TWG5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

293826:AMET RS14070
gene id: 293826:AMET_RS14070
uniprot id: A6TS36
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

293826:AMET RS13060
gene id: 293826:AMET_RS13060
uniprot id: A6TRI2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

293826:AMET RS26600
gene id: 293826:AMET_RS26600
uniprot id: A6TTK1
names: Similarity
messages: Belongs to the P(II) protein family.

293826:AMET RS08090
gene id: 293826:AMET_RS08090
uniprot id: A6TNP5
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS12945
gene id: 293826:AMET_RS12945
uniprot id: A6TRF9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

293826:AMET RS13210
gene id: 293826:AMET_RS13210
uniprot id: A6TRL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

293826:AMET RS22655
gene id: 293826:AMET_RS22655
uniprot id: A6TWN6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

293826:AMET RS05095
gene id: 293826:AMET_RS05095
uniprot id: A6TM31
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS01730
gene id: 293826:AMET_RS01730
uniprot id: A6TK49
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

293826:AMET RS00565
gene id: 293826:AMET_RS00565
uniprot id: A6TJH2
names: Similarity
messages: Belongs to the peptidase S58 family.

293826:AMET RS22105
gene id: 293826:AMET_RS22105
uniprot id: A6TWC8
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

293826:AMET RS17945
gene id: 293826:AMET_RS17945
uniprot id: A6TUA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Membrane

293826:AMET RS03560
gene id: 293826:AMET_RS03560
uniprot id: A6TL73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

293826:AMET RS15590
gene id: 293826:AMET_RS15590
uniprot id: A6TSZ0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

293826:AMET RS22220
gene id: 293826:AMET_RS22220
uniprot id: A6TWF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

293826:AMET RS18310
gene id: 293826:AMET_RS18310
uniprot id: A6TUH7
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS22710
gene id: 293826:AMET_RS22710
uniprot id: A6TWP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

293826:AMET RS20970
gene id: 293826:AMET_RS20970
uniprot id: A6TVY1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

293826:AMET RS04020
gene id: 293826:AMET_RS04020
uniprot id: A6TLH1
names: Similarity
messages: Belongs to the asp23 family.

293826:AMET RS08460
gene id: 293826:AMET_RS08460
uniprot id: A6TNX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

293826:AMET RS08280
gene id: 293826:AMET_RS08280
uniprot id: A6TNT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS18260
gene id: 293826:AMET_RS18260
uniprot id: A6TUG7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS13260
gene id: 293826:AMET_RS13260
uniprot id: A6TRM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

293826:AMET RS02860
gene id: 293826:AMET_RS02860
uniprot id: A6TKS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

293826:AMET RS04035
gene id: 293826:AMET_RS04035
uniprot id: A6TLH4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

293826:AMET RS12465
gene id: 293826:AMET_RS12465
uniprot id: A6TR58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

293826:AMET RS02805
gene id: 293826:AMET_RS02805
uniprot id: A6TKR6
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

293826:AMET RS04570
gene id: 293826:AMET_RS04570
uniprot id: A6TLS8
names: Similarity
messages: Belongs to the GARS family.

293826:AMET RS20490
gene id: 293826:AMET_RS20490
uniprot id: A6TVN9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

293826:AMET RS07320
gene id: 293826:AMET_RS07320
uniprot id: A6TNA8
names: Similarity
messages: Belongs to the arsA ATPase family.

293826:AMET RS01365
gene id: 293826:AMET_RS01365
uniprot id: A6TJX7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the PduL family.
messages: Formed by 2 beta-barrels, each is capped on both ends by short alpha-helices.
messages: Involved in 1,2-propanediol (1,2-PD) utilization within the bacterial microcompartment (BMC) dedicated to 1,2-PD degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.
messages: There are 2 Zn(2+) ions per monomer; Zn(2+) and CoA bind inbetween the 2 domains in each monomer.

293826:AMET RS14625
gene id: 293826:AMET_RS14625
uniprot id: A6TSE9
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS20130
gene id: 293826:AMET_RS20130
uniprot id: A6TVG5
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

293826:AMET RS05945
gene id: 293826:AMET_RS05945
uniprot id: A6TMJ6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

293826:AMET RS00845
gene id: 293826:AMET_RS00845
uniprot id: A6TJM4
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

293826:AMET RS16635
gene id: 293826:AMET_RS16635
uniprot id: A6TTJ6
names: Similarity
messages: Belongs to the glutamine synthetase family.

293826:AMET RS06375
gene id: 293826:AMET_RS06375
uniprot id: A6TMS7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

293826:AMET RS20555
gene id: 293826:AMET_RS20555
uniprot id: A6TVQ2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

293826:AMET RS11435
gene id: 293826:AMET_RS11435
uniprot id: A6TQK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

293826:AMET RS13425
gene id: 293826:AMET_RS13425
uniprot id: A6TRQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

293826:AMET RS13635
gene id: 293826:AMET_RS13635
uniprot id: A6TRU4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

293826:AMET RS16280
gene id: 293826:AMET_RS16280
uniprot id: A6TTC3
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS22575
gene id: 293826:AMET_RS22575
uniprot id: A6TWM3
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS08530
gene id: 293826:AMET_RS08530
uniprot id: A6TNY4
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

293826:AMET RS06930
gene id: 293826:AMET_RS06930
uniprot id: A6TN37
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

293826:AMET RS23585
gene id: 293826:AMET_RS23585
uniprot id: A6TX71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS23410
gene id: 293826:AMET_RS23410
uniprot id: A6TM42
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

293826:AMET RS17300
gene id: 293826:AMET_RS17300
uniprot id: A6TTX9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

293826:AMET RS17845
gene id: 293826:AMET_RS17845
uniprot id: A6TU85
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

293826:AMET RS22350
gene id: 293826:AMET_RS22350
uniprot id: A6TWH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

293826:AMET RS03570
gene id: 293826:AMET_RS03570
uniprot id: A6TL75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

293826:AMET RS05900
gene id: 293826:AMET_RS05900
uniprot id: A6TMI6
names: Similarity
messages: Belongs to the EamA transporter family.

293826:AMET RS06190
gene id: 293826:AMET_RS06190
uniprot id: A6TMP3
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS04865
gene id: 293826:AMET_RS04865
uniprot id: A6TLY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

293826:AMET RS08070
gene id: 293826:AMET_RS08070
uniprot id: A6TNP1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

293826:AMET RS20235
gene id: 293826:AMET_RS20235
uniprot id: A6TVI5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

293826:AMET RS19925
gene id: 293826:AMET_RS19925
uniprot id: A6TVC4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

293826:AMET RS23175
gene id: 293826:AMET_RS23175
uniprot id: A6TWZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

293826:AMET RS17010
gene id: 293826:AMET_RS17010
uniprot id: A6TTS1
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS22345
gene id: 293826:AMET_RS22345
uniprot id: A6TWH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

293826:AMET RS23135
gene id: 293826:AMET_RS23135
uniprot id: A6TWY3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

293826:AMET RS02965
gene id: 293826:AMET_RS02965
uniprot id: A6TKU9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

293826:AMET RS03030
gene id: 293826:AMET_RS03030
uniprot id: A6TKW2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

293826:AMET RS14330
gene id: 293826:AMET_RS14330
uniprot id: A6TS90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

293826:AMET RS10780
gene id: 293826:AMET_RS10780
uniprot id: A6TQ74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

293826:AMET RS07820
gene id: 293826:AMET_RS07820
uniprot id: A6TNJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

293826:AMET RS14210
gene id: 293826:AMET_RS14210
uniprot id: A6TS64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane

293826:AMET RS06830
gene id: 293826:AMET_RS06830
uniprot id: A6TN15
names: Subcellular Location Annotation
messages: Membrane

293826:AMET RS04525
gene id: 293826:AMET_RS04525
uniprot id: A6TLR9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

293826:AMET RS06740
gene id: 293826:AMET_RS06740
uniprot id: A6TMZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

293826:AMET RS13145
gene id: 293826:AMET_RS13145
uniprot id: A6TRJ9
names: Similarity
messages: Belongs to the peptidase M16 family.

293826:AMET RS04115
gene id: 293826:AMET_RS04115
uniprot id: A6TLJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

293826:AMET RS16485
gene id: 293826:AMET_RS16485
uniprot id: A6TTG6
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

293826:AMET RS22315
gene id: 293826:AMET_RS22315
uniprot id: A6TWH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

293826:AMET RS02820
gene id: 293826:AMET_RS02820
uniprot id: A6TKR9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

293826:AMET RS05395
gene id: 293826:AMET_RS05395
uniprot id: A6TM88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

293826:AMET RS10185
gene id: 293826:AMET_RS10185
uniprot id: A6TPV4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

293826:AMET RS02900
gene id: 293826:AMET_RS02900
uniprot id: A6TKT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

293826:AMET RS03255
gene id: 293826:AMET_RS03255
uniprot id: A6TL10
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

293826:AMET RS16300
gene id: 293826:AMET_RS16300
uniprot id: A6TTC7
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

293826:AMET RS07945
gene id: 293826:AMET_RS07945
uniprot id: A6TNM1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.