29088:AURKB
gene id: 29088:AURKB
uniprot id: A0A2Y9HFH7
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

29088:KCNN3
gene id: 29088:KCNN3
uniprot id: A0A2Y9GI78
names: Subcellular Location Annotation
messages: Membrane

29088:AARS2
gene id: 29088:AARS2
uniprot id: A0A2Y9H7L2
names: Caution
names: Cofactor
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: ISGylated.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

29088:ACOXL
gene id: 29088:ACOXL
uniprot id: A0A2Y9HNY2
names: Similarity
messages: Belongs to the acyl-CoA oxidase family.

29088:MCM7
gene id: 29088:MCM7
uniprot id: A0A2Y9GDM6
uniprot id: A0A8M1MBD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

29088:TRARG1
gene id: 29088:TRARG1
uniprot id: A0A8M1MV60
names: Similarity
messages: Belongs to the CD225/Dispanin family.

29088:GRB2
gene id: 29088:GRB2
uniprot id: A0A2Y9GF83
names: Subcellular Location Annotation
messages: Endosome
messages: Golgi apparatus
messages: Nucleus

29088:HOXC12
gene id: 29088:HOXC12
uniprot id: A0A2Y9GXA3
names: Subcellular Location Annotation
messages: Nucleus

29088:ANK2
gene id: 29088:ANK2
uniprot id: A0A8M1M7M4
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

29088:CDC26
gene id: 29088:CDC26
uniprot id: A0A2Y9H682
names: Function
names: Similarity
messages: Belongs to the CDC26 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.

29088:PAPPA2
gene id: 29088:PAPPA2
uniprot id: A0A8M1MG98
names: Similarity
messages: Belongs to the peptidase M43B family.

29088:DPYSL2
gene id: 29088:DPYSL2
uniprot id: A0A2Y9HZC4
uniprot id: A0A8M1MBP2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

29088:CD14
gene id: 29088:CD14
uniprot id: A0A2Y9I0U2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lipopolysaccharide (LPS) receptor, a multi-protein complex containing at least CD14, LY96 and TLR4. Interacts with LPAR1.
messages: Cell membrane
messages: Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-).
messages: Golgi apparatus
messages: Membrane raft
messages: Secreted

29088:ANAPC5
gene id: 29088:ANAPC5
uniprot id: A0A2Y9HWV7
uniprot id: A0A2Y9HYE7
uniprot id: A0A8M1MTL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC5 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: spindle

29088:LOC110584266
gene id: 29088:LOC110584266
uniprot id: A0A2Y9HKF8
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:SEMA6C
gene id: 29088:SEMA6C
uniprot id: A0A2Y9GWK2
uniprot id: A0A2Y9GWX9
uniprot id: A0A2Y9H0Y6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:AHR
gene id: 29088:AHR
uniprot id: A0A2Y9H7H2
names: Subcellular Location Annotation
messages: Cytoplasm

29088:G6PC3
gene id: 29088:G6PC3
uniprot id: A0A2Y9GE38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

29088:LOC110576402
gene id: 29088:LOC110576402
uniprot id: A0A2Y9GVL3
names: Subcellular Location Annotation
messages: Membrane

29088:SEC23A
gene id: 29088:SEC23A
uniprot id: A0A2Y9I011
uniprot id: A0A8M1MM86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

29088:PRIMPOL
gene id: 29088:PRIMPOL
uniprot id: A0A2Y9HDL5
uniprot id: A0A2Y9HK23
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

29088:NDUFA10
gene id: 29088:NDUFA10
uniprot id: A0A2Y9G6K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA10 subunit family.
messages: Complex I is composed of 45 different subunits. This a component of the hydrophobic protein fraction.
messages: Mitochondrion matrix

29088:DEFB105B
gene id: 29088:DEFB105B
uniprot id: A0A2Y9HKE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

29088:SLC35A1
gene id: 29088:SLC35A1
uniprot id: A0A2Y9HAW8
uniprot id: A0A8M1MKV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

29088:CDH4
gene id: 29088:CDH4
uniprot id: A0A8M1MKV6
uniprot id: A0A8M1MMV6
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

29088:PLK2
gene id: 29088:PLK2
uniprot id: A0A2Y9I290
uniprot id: A0A8M1MGZ9
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

29088:PTBP1
gene id: 29088:PTBP1
uniprot id: A0A2Y9IBC7
uniprot id: A0A2Y9IC62
uniprot id: A0A2Y9IIV3
uniprot id: A0A8M1MNJ5
uniprot id: A0A8M1MNL5
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110581184
gene id: 29088:LOC110581184
uniprot id: A0A2Y9HBE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:BCAT1
gene id: 29088:BCAT1
uniprot id: A0A2Y9H3Z9
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

29088:STOML3
gene id: 29088:STOML3
uniprot id: A0A2Y9G4C1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

29088:DCAF1
gene id: 29088:DCAF1
uniprot id: A0A8M1MJW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPRBP/DCAF1 family.
messages: Nucleus

29088:FOXK2
gene id: 29088:FOXK2
uniprot id: A0A2Y9GBN6
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110589283
gene id: 29088:LOC110589283
uniprot id: A0A8M1MF46
uniprot id: A0A8M1MIJ5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

29088:NLGN4X
gene id: 29088:NLGN4X
uniprot id: A0A2Y9HCL1
uniprot id: A0A2Y9HET7
uniprot id: A0A8M1M1H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

29088:PTK2B
gene id: 29088:PTK2B
uniprot id: A0A2Y9HS68
uniprot id: A0A2Y9HXJ4
uniprot id: A0A2Y9HZ33
names: Subcellular Location Annotation
messages: Cell membrane
messages: cell cortex
messages: focal adhesion

29088:DNMT1
gene id: 29088:DNMT1
uniprot id: A0A2Y9IBH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

29088:RPL7L1
gene id: 29088:RPL7L1
uniprot id: A0A2Y9H7K7
uniprot id: A0A2Y9H7L7
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

29088:MANBAL
gene id: 29088:MANBAL
uniprot id: A0A2Y9GZQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0239 family.
messages: Membrane

29088:ARL5A
gene id: 29088:ARL5A
uniprot id: A0A2Y9I3B4
uniprot id: A0A2Y9I3K0
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

29088:LOC110574609
gene id: 29088:LOC110574609
uniprot id: A0A2Y9GIP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

29088:DPH5
gene id: 29088:DPH5
uniprot id: A0A2Y9H8Y1
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

29088:USP11
gene id: 29088:USP11
uniprot id: A0A8M1M1W2
uniprot id: A0A8M1M271
uniprot id: A0A8M1M5Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Nucleus

29088:MTCH1
gene id: 29088:MTCH1
uniprot id: A0A2Y9GMK8
uniprot id: A0A2Y9GRA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:IPO8
gene id: 29088:IPO8
uniprot id: A0A2Y9H3H0
names: Subcellular Location Annotation
messages: Cytoplasm

29088:NXPH4
gene id: 29088:NXPH4
uniprot id: A0A2Y9GYJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

29088:PDE3B
gene id: 29088:PDE3B
uniprot id: A0A2Y9GQ85
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

29088:DPAGT1
gene id: 29088:DPAGT1
uniprot id: A0A2Y9HK39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:AKAP8L
gene id: 29088:AKAP8L
uniprot id: A0A2Y9GIH0
uniprot id: A0A2Y9GLX2
uniprot id: A0A8M1M5I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AKAP95 family.
messages: Nucleus matrix

29088:DYNC1LI1
gene id: 29088:DYNC1LI1
uniprot id: A0A2Y9G664
uniprot id: A0A8M1MD87
uniprot id: A0A8M1MGQ4
uniprot id: A0A8M1MLS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

29088:UFL1
gene id: 29088:UFL1
uniprot id: A0A2Y9HAQ8
names: Similarity
messages: Belongs to the UFL1 family.

29088:LOC110570209
gene id: 29088:LOC110570209
uniprot id: A0A2Y9G6T0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

29088:GRINA
gene id: 29088:GRINA
uniprot id: A0A2Y9GXZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

29088:LOC110581909
gene id: 29088:LOC110581909
uniprot id: A0A2Y9H748
uniprot id: A0A8M1M853
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110590680
gene id: 29088:LOC110590680
uniprot id: A0A8M1MJN2
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

29088:LOC110570094
gene id: 29088:LOC110570094
uniprot id: A0A8M1M3Y2
names: Similarity
messages: Belongs to the NAC-beta family.

29088:ZEB1
gene id: 29088:ZEB1
uniprot id: A0A8M1MC77
uniprot id: A0A8M1MCC5
uniprot id: A0A8M1MEF0
uniprot id: A0A8M1MFU0
uniprot id: A0A8M1MKR6
names: Similarity
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

29088:EIF4E1B
gene id: 29088:EIF4E1B
uniprot id: A0A2Y9HIC9
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

29088:RPL27
gene id: 29088:RPL27
uniprot id: A0A2Y9HDU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL27 family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum

29088:SCARB2
gene id: 29088:SCARB2
uniprot id: A0A2Y9I2J7
uniprot id: A0A8M1M8P1
names: Similarity
messages: Belongs to the CD36 family.

29088:CASD1
gene id: 29088:CASD1
uniprot id: A0A8M1MY26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PC-esterase family. CASD1 subfamily.
messages: Membrane

29088:BSPH1
gene id: 29088:BSPH1
uniprot id: A0A2Y9GCM3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:CCDC47
gene id: 29088:CCDC47
uniprot id: A0A2Y9G4W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC47 family.
messages: Rough endoplasmic reticulum membrane

29088:PRKD1
gene id: 29088:PRKD1
uniprot id: A0A2Y9HMZ5
uniprot id: A0A2Y9HN99
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

29088:LOC110582272
gene id: 29088:LOC110582272
uniprot id: A0A8M1MBG0
names: Subcellular Location Annotation
messages: Membrane

29088:SAXO2
gene id: 29088:SAXO2
uniprot id: A0A2Y9GBA7
names: Similarity
messages: Belongs to the FAM154 family.

29088:LOC110580715
gene id: 29088:LOC110580715
uniprot id: A0A2Y9H348
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:CORO1A
gene id: 29088:CORO1A
uniprot id: A0A2Y9I3L4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat coronin family.
messages: Binds actin.
messages: Membrane
messages: cell cortex
messages: cytoskeleton
messages: phagosome membrane

29088:GGT5
gene id: 29088:GGT5
uniprot id: A0A2Y9GWH7
names: Similarity
messages: Belongs to the gamma-glutamyltransferase family.

29088:RMND1
gene id: 29088:RMND1
uniprot id: A0A2Y9HI41
names: Similarity
messages: Belongs to the RMD1/sif2 family.

29088:UNC119B
gene id: 29088:UNC119B
uniprot id: A0A2Y9I5Q0
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

29088:FAM193A
gene id: 29088:FAM193A
uniprot id: A0A2Y9G5F0
names: Similarity
messages: Belongs to the FAM193 family.

29088:LRP1
gene id: 29088:LRP1
uniprot id: A0A2Y9H087
names: Caution
names: Similarity
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:H1-1
gene id: 29088:H1-1
uniprot id: A0A2Y9HLJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

29088:LOC110576908
gene id: 29088:LOC110576908
uniprot id: A0A2Y9GRI4
uniprot id: A0A2Y9GRL7
uniprot id: A0A8M1MVM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

29088:TRMT2B
gene id: 29088:TRMT2B
uniprot id: A0A2Y9GTK6
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:TLR7
gene id: 29088:TLR7
uniprot id: A0A2Y9GP30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

29088:LOC110580459
gene id: 29088:LOC110580459
uniprot id: A0A2Y9H2K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

29088:PALM
gene id: 29088:PALM
uniprot id: A0A2Y9IBA3
names: Similarity
messages: Belongs to the paralemmin family.

29088:SNRPD2
gene id: 29088:SNRPD2
uniprot id: A0A2Y9GCV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
messages: cytosol

29088:NEK9
gene id: 29088:NEK9
uniprot id: A0A2Y9G8E6
uniprot id: A0A8M1MUL5
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

29088:DDA1
gene id: 29088:DDA1
uniprot id: A0A2Y9GI20
names: Similarity
messages: Belongs to the DDA1 family.

29088:EML6
gene id: 29088:EML6
uniprot id: A0A8M1MNC5
names: Function
names: Similarity
messages: Belongs to the WD repeat EMAP family.
messages: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.

29088:ADAMTS1
gene id: 29088:ADAMTS1
uniprot id: A0A2Y9G7H6
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:ZHX2
gene id: 29088:ZHX2
uniprot id: A0A2Y9GYY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

29088:LOC110591756
gene id: 29088:LOC110591756
uniprot id: A0A8M1MDX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

29088:LOC110581665
gene id: 29088:LOC110581665
uniprot id: A0A2Y9HBY8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:DDR1
gene id: 29088:DDR1
uniprot id: A0A8M1MH86
names: Subcellular Location Annotation
messages: Membrane

29088:C11H11orf54
gene id: 29088:C11H11orf54
uniprot id: A0A2Y9G9B6
uniprot id: A0A2Y9GAF0
uniprot id: A0A8M1MQ52
uniprot id: A0A8M1MX77
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
messages: Monomer.
messages: Nucleus

29088:OBSCN
gene id: 29088:OBSCN
uniprot id: A0A8M1MK00
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

29088:ATG2A
gene id: 29088:ATG2A
uniprot id: A0A8M1MNZ0
uniprot id: A0A8M1MNZ7
uniprot id: A0A8M1MQW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Preautophagosomal structure membrane

29088:LOC110575440
gene id: 29088:LOC110575440
uniprot id: A0A2Y9GLL5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

29088:JUN
gene id: 29088:JUN
uniprot id: A0A2Y9GKE7
uniprot id: A0A2Y9GKL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

29088:LIG3
gene id: 29088:LIG3
uniprot id: A0A2Y9I6E8
uniprot id: A0A2Y9I6S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

29088:LOC110578164
gene id: 29088:LOC110578164
uniprot id: A0A8M1MIE4
names: Similarity
messages: Belongs to the peptidase M24 family.

29088:MOGAT1
gene id: 29088:MOGAT1
uniprot id: A0A2Y9I4V8
uniprot id: A0A2Y9IBI8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:CHRNA5
gene id: 29088:CHRNA5
uniprot id: A0A2Y9GFJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:PAPOLA
gene id: 29088:PAPOLA
uniprot id: A0A2Y9G910
uniprot id: A0A2Y9G946
uniprot id: A0A2Y9G987
uniprot id: A0A2Y9GCN7
uniprot id: A0A8M1MK84
uniprot id: A0A8M1MK87
uniprot id: A0A8M1MNK5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

29088:PKIA
gene id: 29088:PKIA
uniprot id: A0A2Y9GXA4
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

29088:ROM1
gene id: 29088:ROM1
uniprot id: A0A2Y9GPR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRPH2/ROM1 family.
messages: Membrane

29088:LOC110580434
gene id: 29088:LOC110580434
uniprot id: A0A8M1MAH1
names: Similarity
messages: Belongs to the MIF family.

29088:NAGA
gene id: 29088:NAGA
uniprot id: A0A2Y9GW12
uniprot id: A0A2Y9GW56
uniprot id: A0A8M1MD31
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

29088:NDUFA8
gene id: 29088:NDUFA8
uniprot id: A0A2Y9H5P4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion intermembrane space

29088:MCPH1
gene id: 29088:MCPH1
uniprot id: A0A2Y9HKG4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex.
messages: Interacts with CDC27 and maybe other components of the APC/C complex. Interacts with histone variant H2AX under DNA damage conditions.
messages: centrosome

29088:LOC110577293
gene id: 29088:LOC110577293
uniprot id: A0A8M1MDV5
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

29088:GIMAP1
gene id: 29088:GIMAP1
uniprot id: A0A2Y9HA78
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

29088:APEX1
gene id: 29088:APEX1
uniprot id: A0A2Y9HI67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Cytoplasm
messages: Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
messages: Mitochondrion
messages: Nucleus
messages: Probably binds two magnesium or manganese ions per subunit.

29088:TRAPPC5
gene id: 29088:TRAPPC5
uniprot id: A0A2Y9IAT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: cis-Golgi network

29088:CSTF1
gene id: 29088:CSTF1
uniprot id: A0A2Y9G339
names: Subcellular Location Annotation
messages: Nucleus

29088:DCP2
gene id: 29088:DCP2
uniprot id: A0A2Y9HSP6
names: Similarity
messages: Belongs to the Nudix hydrolase family. DCP2 subfamily.

29088:FIP1L1
gene id: 29088:FIP1L1
uniprot id: A0A2Y9I064
uniprot id: A0A2Y9I069
uniprot id: A0A2Y9I0I2
uniprot id: A0A2Y9I0P5
uniprot id: A0A2Y9I569
uniprot id: A0A2Y9I737
uniprot id: A0A8M1M4U8
uniprot id: A0A8M1M4V3
uniprot id: A0A8M1M4W3
uniprot id: A0A8M1M4W6
uniprot id: A0A8M1M4X1
uniprot id: A0A8M1M4X6
uniprot id: A0A8M1M549
uniprot id: A0A8M1M555
uniprot id: A0A8M1M560
uniprot id: A0A8M1M565
uniprot id: A0A8M1M570
uniprot id: A0A8M1M575
uniprot id: A0A8M1M583
uniprot id: A0A8M1M588
uniprot id: A0A8M1M795
uniprot id: A0A8M1M7A0
uniprot id: A0A8M1M7A5
uniprot id: A0A8M1M7A9
uniprot id: A0A8M1M7B4
uniprot id: A0A8M1M7B9
uniprot id: A0A8M1M7C4
uniprot id: A0A8M1M7D0
uniprot id: A0A8M1M8R5
uniprot id: A0A8M1M8S0
uniprot id: A0A8M1M8S3
uniprot id: A0A8M1M8S7
uniprot id: A0A8M1M8T2
uniprot id: A0A8M1M8T7
uniprot id: A0A8M1M8U4
uniprot id: A0A8M1M8U7
uniprot id: A0A8M1MCW7
uniprot id: A0A8M1MCX2
uniprot id: A0A8M1MCX9
uniprot id: A0A8M1MCY4
uniprot id: A0A8M1MCY9
uniprot id: A0A8M1MCZ4
uniprot id: A0A8M1MD00
uniprot id: A0A8M1MD08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

29088:LOC110588598
gene id: 29088:LOC110588598
uniprot id: A0A8M1M686
names: Function
names: Similarity
messages: Belongs to the CDC123 family.
messages: Required for S phase entry of the cell cycle.

29088:HTR2C
gene id: 29088:HTR2C
uniprot id: A0A2Y9GS57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:FNTA
gene id: 29088:FNTA
uniprot id: A0A2Y9GDR5
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

29088:ADGRL2
gene id: 29088:ADGRL2
uniprot id: A0A2Y9H2M1
uniprot id: A0A2Y9H2N6
uniprot id: A0A2Y9H2Q3
uniprot id: A0A2Y9H9A5
uniprot id: A0A8M1M9E0
uniprot id: A0A8M1M9M0
names: Subcellular Location Annotation
messages: Membrane

29088:CASKIN1
gene id: 29088:CASKIN1
uniprot id: A0A2Y9HWI4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

29088:CNKSR2
gene id: 29088:CNKSR2
uniprot id: A0A2Y9GFN0
uniprot id: A0A2Y9GFT4
uniprot id: A0A2Y9GFU5
uniprot id: A0A2Y9GKG9
names: Similarity
messages: Belongs to the CNKSR family.

29088:CDK14
gene id: 29088:CDK14
uniprot id: A0A2Y9H5X4
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:OVOL3
gene id: 29088:OVOL3
uniprot id: A0A2Y9HY29
names: Subcellular Location Annotation
messages: Nucleus

29088:ZWILCH
gene id: 29088:ZWILCH
uniprot id: A0A2Y9HJA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZWILCH family.
messages: Component of the RZZ complex.
messages: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
messages: kinetochore

29088:MRPL42
gene id: 29088:MRPL42
uniprot id: A0A2Y9GVD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL42 family.
messages: Mitochondrion

29088:FUCA2
gene id: 29088:FUCA2
uniprot id: A0A8M1MHL1
uniprot id: A0A8M1MJP2
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

29088:MAPK4
gene id: 29088:MAPK4
uniprot id: A0A2Y9GS12
uniprot id: A0A2Y9GW08
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

29088:KPNB1
gene id: 29088:KPNB1
uniprot id: A0A2Y9IFM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the importin beta family. Importin beta-1 subfamily.
messages: Cytoplasm

29088:VAMP5
gene id: 29088:VAMP5
uniprot id: A0A2Y9HNK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

29088:NT5E
gene id: 29088:NT5E
uniprot id: A0A2Y9HBF2
uniprot id: A0A8M1MKZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-nucleotidase family.
messages: Membrane

29088:LOC110582506
gene id: 29088:LOC110582506
uniprot id: A0A8M1MB53
uniprot id: A0A8M1MCI7
uniprot id: A0A8M1MH56
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

29088:ATP7A
gene id: 29088:ATP7A
uniprot id: A0A2Y9G6D8
uniprot id: A0A8M1M4U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

29088:CSGALNACT2
gene id: 29088:CSGALNACT2
uniprot id: A0A2Y9HVG6
uniprot id: A0A2Y9I2D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

29088:PDHA2
gene id: 29088:PDHA2
uniprot id: A0A2Y9GAS0
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

29088:MIDN
gene id: 29088:MIDN
uniprot id: A0A2Y9IAL1
uniprot id: A0A2Y9IEF0
uniprot id: A0A2Y9IH61
uniprot id: A0A8M1MLI0
names: Subcellular Location Annotation
messages: Nucleus

29088:CUEDC2
gene id: 29088:CUEDC2
uniprot id: A0A2Y9HV73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUEDC2 family.
messages: Cytoplasm
messages: Nucleus

29088:LOC110590300
gene id: 29088:LOC110590300
uniprot id: A0A2Y9HYI1
uniprot id: A0A2Y9HYV8
names: Subcellular Location Annotation
messages: Secreted

29088:OAT
gene id: 29088:OAT
uniprot id: A0A2Y9I6F9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

29088:FAM3D
gene id: 29088:FAM3D
uniprot id: A0A2Y9HMP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

29088:ZMPSTE24
gene id: 29088:ZMPSTE24
uniprot id: A0A2Y9GJS4
uniprot id: A0A2Y9GQ24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

29088:LOC110581603
gene id: 29088:LOC110581603
uniprot id: A0A2Y9H6F2
uniprot id: A0A8M1MRM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110585880
gene id: 29088:LOC110585880
uniprot id: A0A8M1MDH0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

29088:BSN
gene id: 29088:BSN
uniprot id: A0A2Y9GZA3
names: Subcellular Location Annotation
messages: Presynaptic active zone

29088:DEFB114
gene id: 29088:DEFB114
uniprot id: A0A2Y9HD19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

29088:MED21
gene id: 29088:MED21
uniprot id: A0A2Y9H8X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 21 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

29088:ALDH1A1
gene id: 29088:ALDH1A1
uniprot id: A0A2Y9HEG6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

29088:LPAR2
gene id: 29088:LPAR2
uniprot id: A0A2Y9GHY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:ARHGDIA
gene id: 29088:ARHGDIA
uniprot id: A0A2Y9GBS2
names: Similarity
messages: Belongs to the Rho GDI family.

29088:AVPR1B
gene id: 29088:AVPR1B
uniprot id: A0A2Y9GWT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.

29088:TOR1AIP1
gene id: 29088:TOR1AIP1
uniprot id: A0A2Y9GH49
uniprot id: A0A2Y9GM21
uniprot id: A0A8M1MGT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOR1AIP family.
messages: Membrane

29088:AMT
gene id: 29088:AMT
uniprot id: A0A2Y9GTL4
uniprot id: A0A8M1MUN5
uniprot id: A0A8M1MWG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvT family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

29088:CALR
gene id: 29088:CALR
uniprot id: A0A2Y9IA69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen

29088:SCN8A
gene id: 29088:SCN8A
uniprot id: A0A2Y9IA53
uniprot id: A0A2Y9IDZ6
uniprot id: A0A2Y9IGQ6
uniprot id: A0A8M1MCK0
uniprot id: A0A8M1MIP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

29088:NCEH1
gene id: 29088:NCEH1
uniprot id: A0A2Y9I3E8
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

29088:LOC110580198
gene id: 29088:LOC110580198
uniprot id: A0A2Y9H7P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

29088:CPSF4
gene id: 29088:CPSF4
uniprot id: A0A2Y9GA55
uniprot id: A0A2Y9GA82
uniprot id: A0A2Y9GE10
uniprot id: A0A8M1MLD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

29088:ATP6V1D
gene id: 29088:ATP6V1D
uniprot id: A0A2Y9GCB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase D subunit family.
messages: cilium
messages: clathrin-coated vesicle membrane

29088:IZUMO2
gene id: 29088:IZUMO2
uniprot id: A0A2Y9GDK3
names: Similarity
messages: Belongs to the Izumo family.

29088:SLC5A9
gene id: 29088:SLC5A9
uniprot id: A0A8M1M993
uniprot id: A0A8M1M9H8
uniprot id: A0A8M1MD03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

29088:STT3A
gene id: 29088:STT3A
uniprot id: A0A2Y9HKQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

29088:INPPL1
gene id: 29088:INPPL1
uniprot id: A0A2Y9IDG0
names: Similarity
names: Subcellular Location Annotation
messages: Basal cell membrane
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane
messages: Nucleus speckle
messages: filopodium
messages: lamellipodium
messages: spindle pole

29088:NFE2L3
gene id: 29088:NFE2L3
uniprot id: A0A2Y9H1M4
uniprot id: A0A8M1MTY6
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

29088:LOC110583606
gene id: 29088:LOC110583606
uniprot id: A0A2Y9HBZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

29088:TMEM121
gene id: 29088:TMEM121
uniprot id: A0A8M1MLG3
names: Similarity
messages: Belongs to the TMEM121 family.

29088:CFAP97D1
gene id: 29088:CFAP97D1
uniprot id: A0A2Y9GE69
uniprot id: A0A8M1MUL7
names: Similarity
messages: Belongs to the CFAP97 family.

29088:SPRTN
gene id: 29088:SPRTN
uniprot id: A0A2Y9HJF2
uniprot id: A0A2Y9HQ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Spartan family.
messages: Chromosome
messages: Nucleus

29088:PIM3
gene id: 29088:PIM3
uniprot id: A0A2Y9GVV1
uniprot id: A0A8M1MCW4
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

29088:LOC110591405
gene id: 29088:LOC110591405
uniprot id: A0A2Y9I277
uniprot id: A0A2Y9I2G9
uniprot id: A0A2Y9I8Y3
uniprot id: A0A8M1M4F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

29088:ROCK2
gene id: 29088:ROCK2
uniprot id: A0A8M1MNS4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by RHOA binding. Inhibited by Y-27632.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane
messages: Nucleus
messages: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
messages: centrosome

29088:LOC110585694
gene id: 29088:LOC110585694
uniprot id: A0A2Y9HIA5
names: Similarity
messages: Belongs to the importin alpha family.

29088:TEKT3
gene id: 29088:TEKT3
uniprot id: A0A2Y9HFF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

29088:TOR4A
gene id: 29088:TOR4A
uniprot id: A0A2Y9HBR2
names: Similarity
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.

29088:PRPF4
gene id: 29088:PRPF4
uniprot id: A0A2Y9HAZ4
names: Subcellular Location Annotation
messages: Nucleus speckle

29088:G6PD
gene id: 29088:G6PD
uniprot id: A0A2Y9GHF1
uniprot id: A0A2Y9GKN6
uniprot id: A0A2Y9GME3
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.

29088:GDF9
gene id: 29088:GDF9
uniprot id: A0A2Y9I153
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.
messages: Secreted

29088:MANBA
gene id: 29088:MANBA
uniprot id: A0A2Y9GAP9
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

29088:FAM3A
gene id: 29088:FAM3A
uniprot id: A0A8M1M4L7
uniprot id: A0A8M1M9Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

29088:ZNF215
gene id: 29088:ZNF215
uniprot id: A0A2Y9GQ67
names: Subcellular Location Annotation
messages: Nucleus

29088:PLN
gene id: 29088:PLN
uniprot id: A0A2Y9HBU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholamban family.
messages: Endoplasmic reticulum membrane
messages: Homopentamer.
messages: Membrane
messages: Mitochondrion membrane
messages: Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.
messages: Sarcoplasmic reticulum membrane

29088:LOC110582733
gene id: 29088:LOC110582733
uniprot id: A0A2Y9HGE0
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

29088:EIF4E3
gene id: 29088:EIF4E3
uniprot id: A0A2Y9HMM4
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

29088:SNX5
gene id: 29088:SNX5
uniprot id: A0A2Y9HXH1
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

29088:C4H8orf82
gene id: 29088:C4H8orf82
uniprot id: A0A2Y9GYC4
names: Similarity
messages: Belongs to the UPF0598 family.

29088:PPM1E
gene id: 29088:PPM1E
uniprot id: A0A2Y9I8I4
names: Similarity
messages: Belongs to the PP2C family.

29088:CDH3
gene id: 29088:CDH3
uniprot id: A0A2Y9ICH8
uniprot id: A0A8M1MW29
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

29088:CHGA
gene id: 29088:CHGA
uniprot id: A0A2Y9G8H2
uniprot id: A0A2Y9GB42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

29088:GDNF
gene id: 29088:GDNF
uniprot id: A0A2Y9HQL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

29088:LOC110583104
gene id: 29088:LOC110583104
uniprot id: A0A8M1MHE1
uniprot id: A0A8M1MJH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b5 family.
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Endoplasmic reticulum

29088:LOC110572280
gene id: 29088:LOC110572280
uniprot id: A0A8M1MLY5
names: Similarity
messages: Belongs to the CWF19 family.

29088:MMP19
gene id: 29088:MMP19
uniprot id: A0A8M1MAC5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

29088:LOC110576106
gene id: 29088:LOC110576106
uniprot id: A0A2Y9GUE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110582351
gene id: 29088:LOC110582351
uniprot id: A0A2Y9H8R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110592705
gene id: 29088:LOC110592705
uniprot id: A0A8M1M8Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

29088:ACADL
gene id: 29088:ACADL
uniprot id: A0A2Y9I494
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Homotetramer.
messages: Mitochondrion matrix

29088:HEXA
gene id: 29088:HEXA
uniprot id: A0A2Y9HDF3
uniprot id: A0A2Y9HDP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

29088:CLPTM1
gene id: 29088:CLPTM1
uniprot id: A0A2Y9GD97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

29088:HBQ1
gene id: 29088:HBQ1
uniprot id: A0A2Y9HWZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the globin family.
messages: Heterotetramer of two alpha chains and two beta chains.
messages: Involved in oxygen transport from the lung to the various peripheral tissues.

29088:LOC110580615
gene id: 29088:LOC110580615
uniprot id: A0A2Y9H7X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

29088:ARSK
gene id: 29088:ARSK
uniprot id: A0A2Y9HN53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Lysosome

29088:LOC110586612
gene id: 29088:LOC110586612
uniprot id: A0A2Y9H3T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:CXCL12
gene id: 29088:CXCL12
uniprot id: A0A2Y9HWJ8
uniprot id: A0A2Y9I2W2
names: Similarity
messages: Belongs to the intercrine alpha (chemokine CxC) family.

29088:LOC110575607
gene id: 29088:LOC110575607
uniprot id: A0A8M1MH82
uniprot id: A0A8M1MJB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

29088:PSD4
gene id: 29088:PSD4
uniprot id: A0A2Y9HMZ3
uniprot id: A0A2Y9HN60
uniprot id: A0A2Y9HNF1
uniprot id: A0A8M1MVI7
names: Subcellular Location Annotation
messages: Membrane
messages: ruffle membrane

29088:FAM3C
gene id: 29088:FAM3C
uniprot id: A0A2Y9I065
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

29088:TNFRSF8
gene id: 29088:TNFRSF8
uniprot id: A0A2Y9GLQ4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:KCNK12
gene id: 29088:KCNK12
uniprot id: A0A2Y9HZ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

29088:MRPL41
gene id: 29088:MRPL41
uniprot id: A0A2Y9H4Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

29088:MFSD6
gene id: 29088:MFSD6
uniprot id: A0A2Y9I8X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

29088:UCHL5
gene id: 29088:UCHL5
uniprot id: A0A2Y9GSL5
uniprot id: A0A2Y9GWU4
uniprot id: A0A2Y9GYF3
names: Similarity
messages: Belongs to the peptidase C12 family.

29088:NKX2-5
gene id: 29088:NKX2-5
uniprot id: A0A2Y9HW22
names: Subcellular Location Annotation
messages: Nucleus

29088:HBS1L
gene id: 29088:HBS1L
uniprot id: A0A2Y9HAX5
uniprot id: A0A2Y9HHD2
uniprot id: A0A8M1MKK9
names: Subcellular Location Annotation
messages: Cytoplasm

29088:LOC110579611
gene id: 29088:LOC110579611
uniprot id: A0A2Y9H051
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

29088:MCU
gene id: 29088:MCU
uniprot id: A0A8M1MII3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Forms a well-packed pentamer with an overall cylindrical shape. The inner core of the pentamer is formed with the second transmembrane region and the second coiled-coil region: while the transmembrane regions pack into a five-helix bundle having a largely polar pore across the membrane, the coiled-coil outside the membrane forms a pentamer with a hydrophobic core. The inner core is wrapped by the first transmembrane region through contacts between the first and the second transmembrane regions. The second transmembrane is followed by the inner juxtamembrane region (IJMH) that orients at a wide angle relative to the second transmembrane. The two core domains are held together on the periphery by the outer juxtamembrane helix (OJMH).
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

29088:LOC110578462
gene id: 29088:LOC110578462
uniprot id: A0A8M1MH78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the annexin family.
messages: Membrane
messages: basement membrane

29088:KCNE5
gene id: 29088:KCNE5
uniprot id: A0A2Y9G788
names: Similarity
messages: Belongs to the potassium channel KCNE family.

29088:LAMTOR4
gene id: 29088:LAMTOR4
uniprot id: A0A2Y9G9W4
uniprot id: A0A8M1MB56
uniprot id: A0A8M1MDG0
uniprot id: A0A8M1MJP0
names: Similarity
messages: Belongs to the LAMTOR4 family.

29088:MFAP2
gene id: 29088:MFAP2
uniprot id: A0A2Y9GMN0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:PRPSAP2
gene id: 29088:PRPSAP2
uniprot id: A0A2Y9HES4
uniprot id: A0A8M1MX37
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

29088:CCN2
gene id: 29088:CCN2
uniprot id: A0A2Y9HB05
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:ATP5MG
gene id: 29088:ATP5MG
uniprot id: A0A2Y9HRA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion

29088:UCHL1
gene id: 29088:UCHL1
uniprot id: A0A2Y9I727
names: Similarity
messages: Belongs to the peptidase C12 family.

29088:PAICS
gene id: 29088:PAICS
uniprot id: A0A2Y9I0D0
uniprot id: A0A8M1M4U2
uniprot id: A0A8M1M544
names: Similarity
names: Subunit
messages: Homooctamer.
messages: In the C-terminal section; belongs to the AIR carboxylase family. Class II subfamily.
messages: In the N-terminal section; belongs to the SAICAR synthetase family.

29088:DTX4
gene id: 29088:DTX4
uniprot id: A0A2Y9GMV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

29088:LOC110589650
gene id: 29088:LOC110589650
uniprot id: A0A2Y9I123
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion
messages: Mitochondrion inner membrane

29088:REEP5
gene id: 29088:REEP5
uniprot id: A0A2Y9HIE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

29088:RACK1
gene id: 29088:RACK1
uniprot id: A0A2Y9H8K1
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

29088:LOC110578137
gene id: 29088:LOC110578137
uniprot id: A0A2Y9GVV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

29088:LOC110592975
gene id: 29088:LOC110592975
uniprot id: A0A2Y9IBZ8
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

29088:KMT5C
gene id: 29088:KMT5C
uniprot id: A0A8M1MZD4
names: Subcellular Location Annotation
messages: Nucleus

29088:SEMA3B
gene id: 29088:SEMA3B
uniprot id: A0A2Y9GY15
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ZNF277
gene id: 29088:ZNF277
uniprot id: A0A2Y9HTT1
uniprot id: A0A2Y9HTU4
names: Similarity
messages: Belongs to the ZNF277 family.

29088:SNU13
gene id: 29088:SNU13
uniprot id: A0A2Y9H042
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

29088:LOC110577263
gene id: 29088:LOC110577263
uniprot id: A0A8M1MCY7
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

29088:FLVCR2
gene id: 29088:FLVCR2
uniprot id: A0A2Y9GBK0
uniprot id: A0A8M1MSW3
names: Subcellular Location Annotation
messages: Membrane

29088:CCNYL1
gene id: 29088:CCNYL1
uniprot id: A0A8M1M6C8
uniprot id: A0A8M1M9X2
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

29088:NECAP1
gene id: 29088:NECAP1
uniprot id: A0A2Y9H8J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

29088:ARSI
gene id: 29088:ARSI
uniprot id: A0A2Y9HTS7
names: Similarity
messages: Belongs to the sulfatase family.

29088:FAM241B
gene id: 29088:FAM241B
uniprot id: A0A2Y9HVY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM241 family.
messages: Membrane

29088:SLC2A10
gene id: 29088:SLC2A10
uniprot id: A0A2Y9H681
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

29088:PEMT
gene id: 29088:PEMT
uniprot id: A0A2Y9HEU5
uniprot id: A0A2Y9HF83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure. Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

29088:CANT1
gene id: 29088:CANT1
uniprot id: A0A2Y9GC38
uniprot id: A0A2Y9GCA5
uniprot id: A0A2Y9GGJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apyrase family.
messages: Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.
messages: extracellular matrix

29088:DERL3
gene id: 29088:DERL3
uniprot id: A0A2Y9H0P0
uniprot id: A0A8M1MWH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Membrane

29088:SLC16A4
gene id: 29088:SLC16A4
uniprot id: A0A2Y9H2F3
uniprot id: A0A2Y9H2G5
uniprot id: A0A2Y9H7C7
names: Subcellular Location Annotation
messages: Membrane

29088:AARS1
gene id: 29088:AARS1
uniprot id: A0A2Y9I8W7
names: Cofactor
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: ISGylated.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

29088:FZD8
gene id: 29088:FZD8
uniprot id: A0A8M1MJV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

29088:TERF1
gene id: 29088:TERF1
uniprot id: A0A2Y9GXF2
uniprot id: A0A8M1MC90
uniprot id: A0A8M1MGV4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
messages: Homodimer.
messages: Nucleus
messages: telomere

29088:SCUBE2
gene id: 29088:SCUBE2
uniprot id: A0A2Y9GU99
uniprot id: A0A8M1MPL0
uniprot id: A0A8M1MRH0
uniprot id: A0A8M1MY01
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:EEF1AKMT1
gene id: 29088:EEF1AKMT1
uniprot id: A0A2Y9G4B7
uniprot id: A0A2Y9G4E3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.
messages: Was originally thought to be an N(6)-adenine-specific DNA methyltransferase based on primary sequence and predicted secondary structure.

29088:AURKC
gene id: 29088:AURKC
uniprot id: A0A2Y9GFS9
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

29088:ELP6
gene id: 29088:ELP6
uniprot id: A0A2Y9GTY0
names: Similarity
messages: Belongs to the ELP6 family.

29088:ALG14
gene id: 29088:ALG14
uniprot id: A0A2Y9H7S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG14 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane

29088:LOC110581679
gene id: 29088:LOC110581679
uniprot id: A0A2Y9H6H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ANXA6
gene id: 29088:ANXA6
uniprot id: A0A2Y9HSP7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
messages: Melanosome

29088:LOC110570908
gene id: 29088:LOC110570908
uniprot id: A0A2Y9GA54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:PPP1R12A
gene id: 29088:PPP1R12A
uniprot id: A0A2Y9G5L1
uniprot id: A0A2Y9G610
uniprot id: A0A8M1MFE7
uniprot id: A0A8M1MKA8
names: Subcellular Location Annotation
names: Subunit
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.
messages: stress fiber

29088:OAS1
gene id: 29088:OAS1
uniprot id: A0A8M1MUG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-5A synthase family.
messages: Cytoplasm

29088:ANKZF1
gene id: 29088:ANKZF1
uniprot id: A0A2Y9I8F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKZF1/VMS1 family.
messages: Cytoplasm

29088:RAN
gene id: 29088:RAN
uniprot id: A0A2Y9HQY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

29088:TMEM245
gene id: 29088:TMEM245
uniprot id: A0A8M1MRM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

29088:POLR3C
gene id: 29088:POLR3C
uniprot id: A0A2Y9H1A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

29088:YIF1B
gene id: 29088:YIF1B
uniprot id: A0A2Y9HYG6
uniprot id: A0A2Y9HYL0
uniprot id: A0A2Y9HYU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

29088:LOC110585524
gene id: 29088:LOC110585524
uniprot id: A0A2Y9HHV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:MAB21L1
gene id: 29088:MAB21L1
uniprot id: A0A2Y9G4L3
names: Similarity
messages: Belongs to the mab-21 family.

29088:MYO10
gene id: 29088:MYO10
uniprot id: A0A2Y9I7C6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

29088:LOC110577299
gene id: 29088:LOC110577299
uniprot id: A0A2Y9GSH4
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

29088:EEF1B2
gene id: 29088:EEF1B2
uniprot id: A0A2Y9ICA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.
messages: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.

29088:CORO2A
gene id: 29088:CORO2A
uniprot id: A0A2Y9HB04
names: Similarity
messages: Belongs to the WD repeat coronin family.

29088:CUBN
gene id: 29088:CUBN
uniprot id: A0A2Y9HL15
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ANXA13
gene id: 29088:ANXA13
uniprot id: A0A2Y9GY02
uniprot id: A0A2Y9GY17
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

29088:TIMP1
gene id: 29088:TIMP1
uniprot id: A0A8M1M5L4
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

29088:MRPL19
gene id: 29088:MRPL19
uniprot id: A0A2Y9HYC1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

29088:TTC21A
gene id: 29088:TTC21A
uniprot id: A0A8M1MDK7
names: Similarity
messages: Belongs to the TTC21 family.

29088:SLC16A3
gene id: 29088:SLC16A3
uniprot id: A0A2Y9GC50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

29088:IYD
gene id: 29088:IYD
uniprot id: A0A2Y9HBV5
uniprot id: A0A2Y9HHK8
names: Subcellular Location Annotation
messages: Cell membrane

29088:DNHD1
gene id: 29088:DNHD1
uniprot id: A0A8M1MXW3
names: Similarity
messages: Belongs to the dynein heavy chain family.

29088:TSEN15
gene id: 29088:TSEN15
uniprot id: A0A2Y9GGM7
uniprot id: A0A8M1MI79
names: Similarity
messages: Belongs to the SEN15 family.

29088:LOC110579492
gene id: 29088:LOC110579492
uniprot id: A0A2Y9GZZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prion family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane

29088:ESCO1
gene id: 29088:ESCO1
uniprot id: A0A2Y9GV36
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110592739
gene id: 29088:LOC110592739
uniprot id: A0A8M1MEB9
names: Caution
names: Similarity
messages: Belongs to the DMBT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:GABBR2
gene id: 29088:GABBR2
uniprot id: A0A8M1MR73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

29088:PTGDR2
gene id: 29088:PTGDR2
uniprot id: A0A8M1MNS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

29088:SET
gene id: 29088:SET
uniprot id: A0A2Y9H571
uniprot id: A0A8M1MU82
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

29088:COL4A5
gene id: 29088:COL4A5
uniprot id: A0A2Y9G5T0
uniprot id: A0A2Y9G8Z5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

29088:OCA2
gene id: 29088:OCA2
uniprot id: A0A2Y9GDK8
names: Subcellular Location Annotation
messages: Membrane

29088:SMG9
gene id: 29088:SMG9
uniprot id: A0A2Y9GCM1
names: Similarity
messages: Belongs to the SMG9 family.

29088:TM2D1
gene id: 29088:TM2D1
uniprot id: A0A2Y9G9J2
uniprot id: A0A2Y9GC16
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110576121
gene id: 29088:LOC110576121
uniprot id: A0A2Y9GNZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:TMTC2
gene id: 29088:TMTC2
uniprot id: A0A2Y9H8C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

29088:EBF1
gene id: 29088:EBF1
uniprot id: A0A2Y9HP10
uniprot id: A0A2Y9HP48
uniprot id: A0A2Y9HP58
uniprot id: A0A2Y9HPG6
uniprot id: A0A2Y9HUB0
uniprot id: A0A2Y9HUE3
uniprot id: A0A2Y9HVQ8
uniprot id: A0A2Y9HVR8
uniprot id: A0A2Y9HVU4
uniprot id: A0A2Y9HVV8
uniprot id: A0A8M1MI78
uniprot id: A0A8M1MJJ1
uniprot id: A0A8M1MPY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

29088:LOC110594057
gene id: 29088:LOC110594057
uniprot id: A0A8M1M5B2
names: Similarity
messages: Belongs to the adenylate kinase family.

29088:PGM2L1
gene id: 29088:PGM2L1
uniprot id: A0A2Y9I8W2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

29088:LOC110588468
gene id: 29088:LOC110588468
uniprot id: A0A2Y9HS89
names: Similarity
messages: Belongs to the HPF1 family.

29088:ACYP2
gene id: 29088:ACYP2
uniprot id: A0A2Y9I3U4
uniprot id: A0A8M1MNG7
names: Caution
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:HOXA2
gene id: 29088:HOXA2
uniprot id: A0A2Y9H178
names: Subcellular Location Annotation
messages: Nucleus

29088:CD164
gene id: 29088:CD164
uniprot id: A0A2Y9HBN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

29088:EIF4EBP3
gene id: 29088:EIF4EBP3
uniprot id: A0A2Y9I846
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

29088:CLDN17
gene id: 29088:CLDN17
uniprot id: A0A2Y9H422
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

29088:PFDN2
gene id: 29088:PFDN2
uniprot id: A0A2Y9GEN4
names: Function
names: Similarity
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

29088:MPPE1
gene id: 29088:MPPE1
uniprot id: A0A8M1MSW6
uniprot id: A0A8M1MSX1
uniprot id: A0A8M1MSX3
uniprot id: A0A8M1MUQ7
uniprot id: A0A8M1MUR1
uniprot id: A0A8M1MW37
uniprot id: A0A8M1MYT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallophosphoesterase superfamily. MPPE1 family.
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Interacts with GPI-anchor proteins. Interacts with TMED10.
messages: Membrane
messages: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.
messages: cis-Golgi network membrane

29088:DPP4
gene id: 29088:DPP4
uniprot id: A0A2Y9IAF9
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase S9B family. DPPIV subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane raft
messages: invadopodium membrane
messages: lamellipodium membrane

29088:PAM
gene id: 29088:PAM
uniprot id: A0A2Y9HZV9
uniprot id: A0A2Y9HZX3
uniprot id: A0A2Y9I4V4
uniprot id: A0A2Y9I4Y2
uniprot id: A0A2Y9I4Z1
uniprot id: A0A2Y9I6S9
uniprot id: A0A2Y9I6U9
uniprot id: A0A8M1MGN2
uniprot id: A0A8M1MGN5
uniprot id: A0A8M1MK29
uniprot id: A0A8M1MQI1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Binds 2 Cu(2+) ions per subunit.
messages: Binds one Zn(2+) ion per subunit.
messages: In the C-terminal section; belongs to the peptidyl-alpha-hydroxyglycine alpha-amidating lyase family.
messages: In the N-terminal section; belongs to the copper type II ascorbate-dependent monooxygenase family.
messages: Membrane
messages: secretory vesicle membrane

29088:PLPPR3
gene id: 29088:PLPPR3
uniprot id: A0A2Y9IF84
uniprot id: A0A2Y9II75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

29088:LOC110577785
gene id: 29088:LOC110577785
uniprot id: A0A2Y9H0A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:NRG1
gene id: 29088:NRG1
uniprot id: A0A2Y9HDW2
uniprot id: A0A2Y9HDW4
uniprot id: A0A2Y9HDZ6
uniprot id: A0A2Y9HE01
uniprot id: A0A2Y9HE90
uniprot id: A0A2Y9HE93
uniprot id: A0A2Y9HK55
uniprot id: A0A2Y9HKF1
uniprot id: A0A2Y9HKF5
uniprot id: A0A8M1M628
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuregulin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

29088:MID2
gene id: 29088:MID2
uniprot id: A0A2Y9G4L8
uniprot id: A0A2Y9G881
names: Subcellular Location Annotation
messages: cytoskeleton

29088:LOC123323164
gene id: 29088:LOC123323164
uniprot id: A0A8M1M353
uniprot id: A0A8M1M629
uniprot id: A0A8M1M6D2
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

29088:TCIRG1
gene id: 29088:TCIRG1
uniprot id: A0A2Y9GNJ1
uniprot id: A0A2Y9GNL6
uniprot id: A0A2Y9GNU8
uniprot id: A0A2Y9GU90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

29088:B4GALT7
gene id: 29088:B4GALT7
uniprot id: A0A2Y9I0P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

29088:DMRTB1
gene id: 29088:DMRTB1
uniprot id: A0A2Y9GS53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

29088:LOC110591181
gene id: 29088:LOC110591181
uniprot id: A0A8M1MK15
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion matrix
messages: Monomer.

29088:UNC93A
gene id: 29088:UNC93A
uniprot id: A0A2Y9HB38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

29088:RPL22L1
gene id: 29088:RPL22L1
uniprot id: A0A2Y9I2U4
uniprot id: A0A2Y9I7Q7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

29088:IL2RG
gene id: 29088:IL2RG
uniprot id: A0A2Y9GAU3
names: Subcellular Location Annotation
messages: Membrane

29088:TSPAN16
gene id: 29088:TSPAN16
uniprot id: A0A2Y9IFG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

29088:CARMIL3
gene id: 29088:CARMIL3
uniprot id: A0A2Y9HP09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

29088:CXCL16
gene id: 29088:CXCL16
uniprot id: A0A2Y9HER4
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110577487
gene id: 29088:LOC110577487
uniprot id: A0A2Y9GTE6
names: Similarity
messages: Belongs to the peptidase M16 family.

29088:GSC
gene id: 29088:GSC
uniprot id: A0A2Y9GB68
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110588689
gene id: 29088:LOC110588689
uniprot id: A0A2Y9HT24
names: Similarity
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

29088:FGF4
gene id: 29088:FGF4
uniprot id: A0A2Y9GSL2
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

29088:GATAD2A
gene id: 29088:GATAD2A
uniprot id: A0A2Y9GIB9
names: Subcellular Location Annotation
messages: Nucleus

29088:IRX3
gene id: 29088:IRX3
uniprot id: A0A2Y9I8X6
uniprot id: A0A2Y9IDA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

29088:PARP6
gene id: 29088:PARP6
uniprot id: A0A2Y9HDA7
uniprot id: A0A2Y9HDE1
uniprot id: A0A2Y9HDN8
uniprot id: A0A8M1MKH1
names: Similarity
messages: Belongs to the ARTD/PARP family.

29088:SLC10A4
gene id: 29088:SLC10A4
uniprot id: A0A2Y9I058
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

29088:DST
gene id: 29088:DST
uniprot id: A0A8M1MLL3
names: Subcellular Location Annotation
messages: cytoskeleton

29088:LOC110578840
gene id: 29088:LOC110578840
uniprot id: A0A8M1MH84
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autoacetylation strongly increases tubulin acetylation.
messages: Belongs to the acetyltransferase ATAT1 family.
messages: Component of the BBSome complex. Interacts with AP2 alpha-adaptins, including AP2A2, but not with AP1 gamma-adaptin (AP1G1/AP1G2); this interaction is required for efficient alpha-tubulin acetylation, hence clathrin-coated pits are sites of microtubule acetylation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly.
messages: axon
messages: clathrin-coated pit
messages: cytoskeleton
messages: focal adhesion
messages: spindle

29088:LOC110570711
gene id: 29088:LOC110570711
uniprot id: A0A2Y9G5X4
names: Similarity
messages: Belongs to the PRR23 family.

29088:PIK3C3
gene id: 29088:PIK3C3
uniprot id: A0A2Y9GS11
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

29088:SATB2
gene id: 29088:SATB2
uniprot id: A0A2Y9I915
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

29088:INSIG1
gene id: 29088:INSIG1
uniprot id: A0A2Y9HAL3
uniprot id: A0A8M1MQT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

29088:CDH19
gene id: 29088:CDH19
uniprot id: A0A2Y9GS96
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

29088:LOC110576415
gene id: 29088:LOC110576415
uniprot id: A0A2Y9GQ44
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:TMC3
gene id: 29088:TMC3
uniprot id: A0A2Y9GDY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

29088:JMY
gene id: 29088:JMY
uniprot id: A0A8M1MPE7
names: Subcellular Location Annotation
messages: Membrane

29088:HGFAC
gene id: 29088:HGFAC
uniprot id: A0A2Y9G2U6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110577745
gene id: 29088:LOC110577745
uniprot id: A0A8M1MG81
uniprot id: A0A8M1MG84
names: Similarity
messages: Belongs to the NAC-beta family.

29088:ANKRD13A
gene id: 29088:ANKRD13A
uniprot id: A0A2Y9I594
uniprot id: A0A2Y9I5F7
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

29088:ASPHD1
gene id: 29088:ASPHD1
uniprot id: A0A2Y9HX70
names: Similarity
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

29088:FAM124A
gene id: 29088:FAM124A
uniprot id: A0A2Y9H0R6
names: Similarity
messages: Belongs to the FAM124 family.

29088:CAND1
gene id: 29088:CAND1
uniprot id: A0A2Y9G865
uniprot id: A0A2Y9G9B4
names: Similarity
messages: Belongs to the CAND family.

29088:PLIN5
gene id: 29088:PLIN5
uniprot id: A0A2Y9IAV6
names: Similarity
messages: Belongs to the perilipin family.

29088:MTX2
gene id: 29088:MTX2
uniprot id: A0A2Y9I3Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

29088:TPST2
gene id: 29088:TPST2
uniprot id: A0A2Y9I571
uniprot id: A0A2Y9I5X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

29088:TMTC3
gene id: 29088:TMTC3
uniprot id: A0A2Y9GUV0
uniprot id: A0A2Y9H0L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

29088:PELO
gene id: 29088:PELO
uniprot id: A0A2Y9HLB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Component of the Pelota-HBS1L complex, a complex that recognizes stalled ribosomes and triggers the No-Go Decay (NGD) pathway. In the Pelota-HBS1L complex, pelo recognizes ribosomes stalled at the 3' end of an mRNA and engages stalled ribosomes by destabilizing mRNA in the mRNA channel.
messages: Cytoplasm

29088:LOC110586427
gene id: 29088:LOC110586427
uniprot id: A0A2Y9HKU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110573135
gene id: 29088:LOC110573135
uniprot id: A0A2Y9GDS1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:SNX19
gene id: 29088:SNX19
uniprot id: A0A2Y9HRB1
uniprot id: A0A8M1MPL5
names: Similarity
messages: Belongs to the sorting nexin family.

29088:ELF4
gene id: 29088:ELF4
uniprot id: A0A8M1M5B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

29088:MGAT5
gene id: 29088:MGAT5
uniprot id: A0A2Y9HI53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Secreted

29088:TNK1
gene id: 29088:TNK1
uniprot id: A0A2Y9HF41
names: Subcellular Location Annotation
messages: Cell membrane

29088:ABCA9
gene id: 29088:ABCA9
uniprot id: A0A8M1MV97
names: Subcellular Location Annotation
messages: Membrane

29088:PSMB1
gene id: 29088:PSMB1
uniprot id: A0A2Y9HC97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

29088:LOC110590152
gene id: 29088:LOC110590152
uniprot id: A0A2Y9H042
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

29088:ANO3
gene id: 29088:ANO3
uniprot id: A0A2Y9GUL0
uniprot id: A0A2Y9GWA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Membrane

29088:TMEM59L
gene id: 29088:TMEM59L
uniprot id: A0A2Y9GI61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:IQSEC1
gene id: 29088:IQSEC1
uniprot id: A0A8M1MSS5
uniprot id: A0A8M1MVZ0
names: Similarity
messages: Belongs to the BRAG family.

29088:LOC110576541
gene id: 29088:LOC110576541
uniprot id: A0A8M1MS28
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

29088:GPHN
gene id: 29088:GPHN
uniprot id: A0A8M1MJP1
uniprot id: A0A8M1MJP4
uniprot id: A0A8M1MJP6
uniprot id: A0A8M1MJP9
uniprot id: A0A8M1MLQ1
uniprot id: A0A8M1MLQ6
uniprot id: A0A8M1MN18
uniprot id: A0A8M1MTR1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
messages: In the C-terminal section; belongs to the MoeA family.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

29088:LDAF1
gene id: 29088:LDAF1
uniprot id: A0A2Y9H874
uniprot id: A0A2Y9HDW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDAF1 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Membrane

29088:IL2RB
gene id: 29088:IL2RB
uniprot id: A0A2Y9GVP2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Cell membrane
messages: Membrane
messages: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. Interacts with SHB upon interleukin stimulation.

29088:LTBP1
gene id: 29088:LTBP1
uniprot id: A0A2Y9HNN5
uniprot id: A0A8M1MLH5
uniprot id: A0A8M1MLH9
uniprot id: A0A8M1MLI4
uniprot id: A0A8M1MLI6
uniprot id: A0A8M1MLI9
uniprot id: A0A8M1MLJ2
uniprot id: A0A8M1MLJ4
uniprot id: A0A8M1MLJ7
uniprot id: A0A8M1MLJ9
uniprot id: A0A8M1MNH1
uniprot id: A0A8M1MNH7
uniprot id: A0A8M1MNI1
uniprot id: A0A8M1MNI6
uniprot id: A0A8M1MNJ1
uniprot id: A0A8M1MPS8
uniprot id: A0A8M1MPT3
uniprot id: A0A8M1MPT7
uniprot id: A0A8M1MPU2
uniprot id: A0A8M1MPU7
uniprot id: A0A8M1MVN7
uniprot id: A0A8M1MVP2
uniprot id: A0A8M1MVP7
uniprot id: A0A8M1MVQ2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:LOC110575327
gene id: 29088:LOC110575327
uniprot id: A0A8M1M1V7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

29088:NEIL3
gene id: 29088:NEIL3
uniprot id: A0A2Y9HDX1
names: Similarity
messages: Belongs to the FPG family.

29088:MMP10
gene id: 29088:MMP10
uniprot id: A0A2Y9HK17
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

29088:DCLRE1A
gene id: 29088:DCLRE1A
uniprot id: A0A2Y9HVG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

29088:AR
gene id: 29088:AR
uniprot id: A0A2Y9GC54
names: Similarity
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.

29088:LOC110590709
gene id: 29088:LOC110590709
uniprot id: A0A8M1MJZ8
names: Similarity
messages: Belongs to the GroES chaperonin family.

29088:BAZ1B
gene id: 29088:BAZ1B
uniprot id: A0A2Y9HWQ3
names: Subcellular Location Annotation
messages: Nucleus

29088:PRICKLE3
gene id: 29088:PRICKLE3
uniprot id: A0A2Y9G7Y2
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

29088:LOC110579370
gene id: 29088:LOC110579370
uniprot id: A0A2Y9H5V4
names: Similarity
messages: Belongs to the BLCAP family.

29088:PCMTD1
gene id: 29088:PCMTD1
uniprot id: A0A2Y9GYD2
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

29088:ARRDC5
gene id: 29088:ARRDC5
uniprot id: A0A2Y9IEW2
names: Similarity
messages: Belongs to the arrestin family.

29088:LOC110573710
gene id: 29088:LOC110573710
uniprot id: A0A8M1M9A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

29088:GOLM1
gene id: 29088:GOLM1
uniprot id: A0A2Y9G440
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

29088:SLC25A32
gene id: 29088:SLC25A32
uniprot id: A0A2Y9GXM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:CNN3
gene id: 29088:CNN3
uniprot id: A0A2Y9H320
uniprot id: A0A8M1M818
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

29088:NACC2
gene id: 29088:NACC2
uniprot id: A0A2Y9H507
names: Subcellular Location Annotation
messages: Nucleus

29088:WDR76
gene id: 29088:WDR76
uniprot id: A0A8M1MLS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Interacts with CUL4A and/or CUL4B.
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

29088:EXOSC2
gene id: 29088:EXOSC2
uniprot id: A0A2Y9H5N3
uniprot id: A0A2Y9HB44
uniprot id: A0A8M1MTA1
uniprot id: A0A8M1MYI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

29088:PLCB2
gene id: 29088:PLCB2
uniprot id: A0A2Y9HH23
uniprot id: A0A2Y9HN87
uniprot id: A0A2Y9HNL6
names: Cofactor
names: Function
messages: Binds 1 Ca(2+) ion per subunit.
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

29088:KALRN
gene id: 29088:KALRN
uniprot id: A0A8M1MSM7
names: Subcellular Location Annotation
messages: Cytoplasm

29088:GHR
gene id: 29088:GHR
uniprot id: A0A2Y9HX90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Cell membrane
messages: Membrane
messages: On growth hormone (GH) binding, forms homodimers and binds JAK2 via a box 1-containing domain. Binding to SOCS3 inhibits JAK2 activation, binding to CIS and SOCS2 inhibits STAT5 activation.
messages: The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.

29088:PITPNM3
gene id: 29088:PITPNM3
uniprot id: A0A8M1MV41
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

29088:LOC110574532
gene id: 29088:LOC110574532
uniprot id: A0A2Y9GII0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:FOXG1
gene id: 29088:FOXG1
uniprot id: A0A2Y9HHW5
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon.

29088:CCR9
gene id: 29088:CCR9
uniprot id: A0A2Y9GL93
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:TIMM13
gene id: 29088:TIMM13
uniprot id: A0A2Y9IAB2
uniprot id: A0A2Y9IER0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

29088:LOC110578577
gene id: 29088:LOC110578577
uniprot id: A0A2Y9GWS1
names: Similarity
messages: Belongs to the LCE family.

29088:ATP6V1C1
gene id: 29088:ATP6V1C1
uniprot id: A0A2Y9GXB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

29088:FAM241A
gene id: 29088:FAM241A
uniprot id: A0A2Y9GM23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM241 family.
messages: Membrane

29088:EZH2
gene id: 29088:EZH2
uniprot id: A0A2Y9HAN6
uniprot id: A0A2Y9HGH0
uniprot id: A0A2Y9HH58
uniprot id: A0A8M1MQT2
uniprot id: A0A8M1MSN8
names: Subcellular Location Annotation
messages: Nucleus

29088:CDK8
gene id: 29088:CDK8
uniprot id: A0A2Y9G4W4
uniprot id: A0A2Y9G823
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:MX2
gene id: 29088:MX2
uniprot id: A0A2Y9G9L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: Cytoplasm

29088:LOC110582460
gene id: 29088:LOC110582460
uniprot id: A0A8M1M8K1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.

29088:TCTN2
gene id: 29088:TCTN2
uniprot id: A0A2Y9HRE2
uniprot id: A0A8M1MSH0
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

29088:C1H3orf70
gene id: 29088:C1H3orf70
uniprot id: A0A2Y9H974
names: Similarity
messages: Belongs to the UPF0524 family.

29088:LOC110570929
gene id: 29088:LOC110570929
uniprot id: A0A2Y9G6Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:CNNM1
gene id: 29088:CNNM1
uniprot id: A0A2Y9I0J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Cell membrane
messages: Membrane
messages: Metal transporter.

29088:LZTFL1
gene id: 29088:LZTFL1
uniprot id: A0A2Y9GHV1
uniprot id: A0A2Y9GI21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTFL1 family.
messages: Cytoplasm
messages: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
messages: Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking.

29088:UNG
gene id: 29088:UNG
uniprot id: A0A2Y9I6E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Monomer. Interacts with FAM72A.
messages: Nucleus

29088:PNMT
gene id: 29088:PNMT
uniprot id: A0A2Y9I8D7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

29088:INKA1
gene id: 29088:INKA1
uniprot id: A0A2Y9GTT7
uniprot id: A0A8M1MKA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

29088:PDE1B
gene id: 29088:PDE1B
uniprot id: A0A2Y9GTC9
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

29088:TSHZ2
gene id: 29088:TSHZ2
uniprot id: A0A2Y9G5X8
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

29088:APOLD1
gene id: 29088:APOLD1
uniprot id: A0A2Y9H474
names: Similarity
messages: Belongs to the apolipoprotein L family.

29088:DSG3
gene id: 29088:DSG3
uniprot id: A0A2Y9GRA7
uniprot id: A0A2Y9GRD6
uniprot id: A0A2Y9GV66
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

29088:TSPAN10
gene id: 29088:TSPAN10
uniprot id: A0A2Y9GEA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

29088:PTPN1
gene id: 29088:PTPN1
uniprot id: A0A2Y9GWB9
uniprot id: A0A8M1MVJ2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

29088:NOX1
gene id: 29088:NOX1
uniprot id: A0A8M1M143
uniprot id: A0A8M1M3M7
uniprot id: A0A8M1M8X0
names: Subcellular Location Annotation
messages: Membrane

29088:ATP7B
gene id: 29088:ATP7B
uniprot id: A0A2Y9G539
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

29088:COLGALT1
gene id: 29088:COLGALT1
uniprot id: A0A2Y9GI77
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

29088:SLC51A
gene id: 29088:SLC51A
uniprot id: A0A2Y9H9C4
names: Subcellular Location Annotation
messages: Membrane

29088:MUC13
gene id: 29088:MUC13
uniprot id: A0A2Y9H9K1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110572629
gene id: 29088:LOC110572629
uniprot id: A0A2Y9GCH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion
messages: Mitochondrion inner membrane

29088:ST3GAL5
gene id: 29088:ST3GAL5
uniprot id: A0A2Y9HMS7
uniprot id: A0A8M1MMJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

29088:SPDYC
gene id: 29088:SPDYC
uniprot id: A0A2Y9GUK9
names: Similarity
messages: Belongs to the Speedy/Ringo family.

29088:SLC31A1
gene id: 29088:SLC31A1
uniprot id: A0A2Y9H645
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

29088:SUZ12
gene id: 29088:SUZ12
uniprot id: A0A2Y9I951
uniprot id: A0A8M1MXT6
names: Similarity
messages: Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.

29088:PDK3
gene id: 29088:PDK3
uniprot id: A0A2Y9IIY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

29088:S100A11
gene id: 29088:S100A11
uniprot id: A0A2Y9GWV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the S-100 family.
messages: Facilitates the differentiation and the cornification of keratinocytes.
messages: Homodimer; disulfide-linked.

29088:ZUP1
gene id: 29088:ZUP1
uniprot id: A0A2Y9HB67
names: Similarity
names: Subunit
messages: Belongs to the peptidase C78 family. ZUFSP subfamily.
messages: Interacts with RPA1 and RPA2.

29088:HSPA14
gene id: 29088:HSPA14
uniprot id: A0A2Y9HL33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Component of ribosome-associated complex (RAC), a heterodimer composed of Hsp70/DnaK-type chaperone HSPA14 and Hsp40/DnaJ-type chaperone DNAJC2.
messages: Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity.
messages: cytosol

29088:LOC110589036
gene id: 29088:LOC110589036
uniprot id: A0A2Y9HU45
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

29088:HNRNPC
gene id: 29088:HNRNPC
uniprot id: A0A2Y9HH09
uniprot id: A0A2Y9HH16
uniprot id: A0A2Y9HH69
uniprot id: A0A2Y9HN21
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

29088:CSNK1G1
gene id: 29088:CSNK1G1
uniprot id: A0A2Y9HJ34
uniprot id: A0A8M1MKL1
uniprot id: A0A8M1MKL7
uniprot id: A0A8M1MMM4
uniprot id: A0A8M1MNX9
uniprot id: A0A8M1MUQ3
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

29088:NLGN2
gene id: 29088:NLGN2
uniprot id: A0A8M1MUE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

29088:LOC110589599
gene id: 29088:LOC110589599
uniprot id: A0A8M1MDU5
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

29088:PPME1
gene id: 29088:PPME1
uniprot id: A0A2Y9IDE5
uniprot id: A0A8M1MSD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily.
messages: Binds PPP2CA and PPP2CB.
messages: Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme.

29088:TAGLN
gene id: 29088:TAGLN
uniprot id: A0A2Y9HKG3
names: Similarity
messages: Belongs to the calponin family.

29088:CNNM4
gene id: 29088:CNNM4
uniprot id: A0A2Y9I5F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Cell membrane
messages: Membrane
messages: Metal transporter.

29088:FAM120B
gene id: 29088:FAM120B
uniprot id: A0A2Y9HBE0
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

29088:SUSD3
gene id: 29088:SUSD3
uniprot id: A0A2Y9HKS3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ATXN1L
gene id: 29088:ATXN1L
uniprot id: A0A2Y9IJ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

29088:TUBB6
gene id: 29088:TUBB6
uniprot id: A0A2Y9GHS5
uniprot id: A0A2Y9GHV9
uniprot id: A0A2Y9GL41
uniprot id: A0A2Y9GMV5
uniprot id: A0A8M1MWS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

29088:LOC110575931
gene id: 29088:LOC110575931
uniprot id: A0A2Y9GS44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIII family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

29088:VPS45
gene id: 29088:VPS45
uniprot id: A0A2Y9GWN4
uniprot id: A0A8M1M881
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

29088:STS
gene id: 29088:STS
uniprot id: A0A2Y9G5R8
uniprot id: A0A2Y9G995
uniprot id: A0A2Y9G9P3
names: Similarity
messages: Belongs to the sulfatase family.

29088:FLAD1
gene id: 29088:FLAD1
uniprot id: A0A2Y9GFB7
uniprot id: A0A2Y9GFG5
uniprot id: A0A2Y9GFI2
names: Function
names: Similarity
messages: Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme.
messages: In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

29088:LOC110580189
gene id: 29088:LOC110580189
uniprot id: A0A8M1M5K5
names: Similarity
messages: Belongs to the SERF family.

29088:RAB39B
gene id: 29088:RAB39B
uniprot id: A0A2Y9GK34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

29088:LOC110589518
gene id: 29088:LOC110589518
uniprot id: A0A2Y9HVX9
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:LOC110586074
gene id: 29088:LOC110586074
uniprot id: A0A2Y9HJD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:GRIK5
gene id: 29088:GRIK5
uniprot id: A0A2Y9HE11
uniprot id: A0A2Y9HF37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

29088:DTX3
gene id: 29088:DTX3
uniprot id: A0A2Y9H0H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

29088:AP2M1
gene id: 29088:AP2M1
uniprot id: A0A2Y9H9H1
uniprot id: A0A2Y9HFE9
uniprot id: A0A8M1MA12
uniprot id: A0A8M1MC57
uniprot id: A0A8M1MI81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cell membrane
messages: coated pit

29088:LOC110585091
gene id: 29088:LOC110585091
uniprot id: A0A8M1MV75
uniprot id: A0A8M1MYX2
names: Subcellular Location Annotation
messages: Nucleus

29088:A3GALT2
gene id: 29088:A3GALT2
uniprot id: A0A2Y9GQH6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Membrane

29088:CNGA4
gene id: 29088:CNGA4
uniprot id: A0A2Y9GQ02
names: Subcellular Location Annotation
messages: Membrane

29088:XRCC1
gene id: 29088:XRCC1
uniprot id: A0A2Y9GCS4
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110578433
gene id: 29088:LOC110578433
uniprot id: A0A2Y9GWM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:GRM5
gene id: 29088:GRM5
uniprot id: A0A2Y9G6X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

29088:TGM5
gene id: 29088:TGM5
uniprot id: A0A2Y9HNC6
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

29088:SPTLC2
gene id: 29088:SPTLC2
uniprot id: A0A2Y9G909
uniprot id: A0A2Y9G958
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

29088:DBNDD1
gene id: 29088:DBNDD1
uniprot id: A0A2Y9IC87
names: Similarity
messages: Belongs to the dysbindin family.

29088:PARD6B
gene id: 29088:PARD6B
uniprot id: A0A2Y9GQU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

29088:TTC9B
gene id: 29088:TTC9B
uniprot id: A0A2Y9I3G5
names: Similarity
messages: Belongs to the TTC9 family.

29088:CDC25B
gene id: 29088:CDC25B
uniprot id: A0A2Y9GZE0
uniprot id: A0A8M1MKX2
uniprot id: A0A8M1MP85
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

29088:REXO4
gene id: 29088:REXO4
uniprot id: A0A2Y9H601
names: Similarity
messages: Belongs to the REXO4 family.

29088:LSM1
gene id: 29088:LSM1
uniprot id: A0A2Y9GDU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: Interacts with SLBP; interaction with SLBP occurs when histone mRNA is being rapidly degraded during the S phase. LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation.

29088:LOC110577173
gene id: 29088:LOC110577173
uniprot id: A0A8M1MV80
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

29088:NPM1
gene id: 29088:NPM1
uniprot id: A0A2Y9HQF5
uniprot id: A0A2Y9HX77
uniprot id: A0A8M1MPU0
names: Similarity
messages: Belongs to the nucleoplasmin family.

29088:LOC110578640
gene id: 29088:LOC110578640
uniprot id: A0A8M1MS83
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

29088:NPY1R
gene id: 29088:NPY1R
uniprot id: A0A2Y9HZ59
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:LOC110586924
gene id: 29088:LOC110586924
uniprot id: A0A2Y9HMI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: cytoskeleton

29088:ALOX15B
gene id: 29088:ALOX15B
uniprot id: A0A2Y9HLR0
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:FAM151A
gene id: 29088:FAM151A
uniprot id: A0A2Y9GNY7
names: Similarity
messages: Belongs to the FAM151 family.

29088:OPRL1
gene id: 29088:OPRL1
uniprot id: A0A2Y9G5I5
uniprot id: A0A2Y9G6M4
uniprot id: A0A8M1MPG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
messages: Membrane
messages: Vesicle

29088:SLC41A3
gene id: 29088:SLC41A3
uniprot id: A0A2Y9HGJ0
uniprot id: A0A8M1ME27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

29088:LOC110580768
gene id: 29088:LOC110580768
uniprot id: A0A8M1MBI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

29088:ABCC2
gene id: 29088:ABCC2
uniprot id: A0A2Y9I0J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

29088:OPN3
gene id: 29088:OPN3
uniprot id: A0A2Y9GGX8
uniprot id: A0A8M1MES6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

29088:DTD2
gene id: 29088:DTD2
uniprot id: A0A8M1MTP6
names: Similarity
messages: Belongs to the DTD family.

29088:KRT40
gene id: 29088:KRT40
uniprot id: A0A2Y9I7G6
names: Similarity
messages: Belongs to the intermediate filament family.

29088:CZIB
gene id: 29088:CZIB
uniprot id: A0A2Y9GLE7
uniprot id: A0A2Y9GQ77
names: Similarity
messages: Belongs to the UPF0587 family.

29088:PAIP2B
gene id: 29088:PAIP2B
uniprot id: A0A2Y9HZL1
names: Similarity
messages: Belongs to the PAIP2 family.

29088:LOC123323420
gene id: 29088:LOC123323420
uniprot id: A0A8M1M261
names: Subcellular Location Annotation
messages: Nucleus

29088:ACTR2
gene id: 29088:ACTR2
uniprot id: A0A2Y9HSK0
uniprot id: A0A8M1MKU8
names: Similarity
messages: Belongs to the actin family.

29088:NDUFAF3
gene id: 29088:NDUFAF3
uniprot id: A0A2Y9GY33
names: Function
names: Subcellular Location Annotation
messages: Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Membrane
messages: Mitochondrion inner membrane
messages: Nucleus

29088:UTP11
gene id: 29088:UTP11
uniprot id: A0A2Y9GJZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

29088:LTBP3
gene id: 29088:LTBP3
uniprot id: A0A2Y9GPS0
uniprot id: A0A2Y9GTM9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:NKD2
gene id: 29088:NKD2
uniprot id: A0A2Y9GU68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm

29088:LOC123325298
gene id: 29088:LOC123325298
uniprot id: A0A8M1MGL1
names: Subcellular Location Annotation
messages: Nucleus

29088:MED23
gene id: 29088:MED23
uniprot id: A0A2Y9HBC5
uniprot id: A0A8M1MIE9
uniprot id: A0A8M1MIF2
uniprot id: A0A8M1MKH0
uniprot id: A0A8M1MLT3
uniprot id: A0A8M1MSE2
uniprot id: A0A8M1MSE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 23 family.
messages: Nucleus

29088:PDS5B
gene id: 29088:PDS5B
uniprot id: A0A2Y9G726
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDS5 family.
messages: Nucleus

29088:SLC26A7
gene id: 29088:SLC26A7
uniprot id: A0A2Y9GXG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

29088:LOC110573433
gene id: 29088:LOC110573433
uniprot id: A0A2Y9GEV8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LHFPL6
gene id: 29088:LHFPL6
uniprot id: A0A8M1M7X9
names: Subcellular Location Annotation
messages: Membrane

29088:IDO1
gene id: 29088:IDO1
uniprot id: A0A2Y9GDV9
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

29088:GGH
gene id: 29088:GGH
uniprot id: A0A2Y9GXB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

29088:UVSSA
gene id: 29088:UVSSA
uniprot id: A0A8M1M971
names: Similarity
messages: Belongs to the UVSSA family.

29088:KCNE2
gene id: 29088:KCNE2
uniprot id: A0A2Y9G7C1
names: Similarity
messages: Belongs to the potassium channel KCNE family.

29088:THUMPD2
gene id: 29088:THUMPD2
uniprot id: A0A2Y9HTL6
uniprot id: A0A2Y9HV25
names: Similarity
messages: Belongs to the methyltransferase superfamily.

29088:PLK4
gene id: 29088:PLK4
uniprot id: A0A2Y9GDI8
uniprot id: A0A8M1M471
names: Subcellular Location Annotation
messages: Cleavage furrow
messages: centriole

29088:SCAMP1
gene id: 29088:SCAMP1
uniprot id: A0A2Y9I7V3
uniprot id: A0A8M1MGA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

29088:CHRNG
gene id: 29088:CHRNG
uniprot id: A0A2Y9H335
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:AS3MT
gene id: 29088:AS3MT
uniprot id: A0A2Y9I0V5
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

29088:ID2
gene id: 29088:ID2
uniprot id: A0A2Y9HNB5
names: Subcellular Location Annotation
messages: Nucleus

29088:PCMT1
gene id: 29088:PCMT1
uniprot id: A0A2Y9HC55
uniprot id: A0A2Y9HIT3
uniprot id: A0A8M1MIC7
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

29088:RDH8
gene id: 29088:RDH8
uniprot id: A0A2Y9IIF9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29088:GTF2IRD1
gene id: 29088:GTF2IRD1
uniprot id: A0A8M1MB23
uniprot id: A0A8M1MBA0
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110579984
gene id: 29088:LOC110579984
uniprot id: A0A2Y9H7P0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

29088:LOC110593873
gene id: 29088:LOC110593873
uniprot id: A0A2Y9IF08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110593618
gene id: 29088:LOC110593618
uniprot id: A0A8M1MAI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:CACTIN
gene id: 29088:CACTIN
uniprot id: A0A8M1MHP9
names: Similarity
messages: Belongs to the CACTIN family.

29088:RPP14
gene id: 29088:RPP14
uniprot id: A0A2Y9HGC1
uniprot id: A0A2Y9HM91
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

29088:LOC110594029
gene id: 29088:LOC110594029
uniprot id: A0A8M1MJI0
uniprot id: A0A8M1MTJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: nucleolus

29088:TSPAN31
gene id: 29088:TSPAN31
uniprot id: A0A2Y9GUQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

29088:TBPL2
gene id: 29088:TBPL2
uniprot id: A0A2Y9HZM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

29088:EIF2S1
gene id: 29088:EIF2S1
uniprot id: A0A2Y9GBC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2-alpha family.
messages: Stress granule

29088:SLC1A5
gene id: 29088:SLC1A5
uniprot id: A0A2Y9GCX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

29088:PAQR8
gene id: 29088:PAQR8
uniprot id: A0A2Y9HD57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

29088:GAD1
gene id: 29088:GAD1
uniprot id: A0A2Y9I3U2
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

29088:UBP1
gene id: 29088:UBP1
uniprot id: A0A2Y9G2E4
uniprot id: A0A2Y9G2Z9
uniprot id: A0A2Y9G510
uniprot id: A0A2Y9G649
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

29088:LOC110581712
gene id: 29088:LOC110581712
uniprot id: A0A2Y9HDD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:NTMT1
gene id: 29088:NTMT1
uniprot id: A0A2Y9H5S8
uniprot id: A0A2Y9H5T9
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

29088:VCAN
gene id: 29088:VCAN
uniprot id: A0A2Y9HUK9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aggrecan/versican proteoglycan family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:LOC110585121
gene id: 29088:LOC110585121
uniprot id: A0A8M1MPB4
names: Similarity
messages: Belongs to the 14-3-3 family.

29088:MCHR1
gene id: 29088:MCHR1
uniprot id: A0A2Y9H017
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

29088:FANCM
gene id: 29088:FANCM
uniprot id: A0A2Y9HZK2
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.

29088:LYZL4
gene id: 29088:LYZL4
uniprot id: A0A2Y9G679
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

29088:TBX15
gene id: 29088:TBX15
uniprot id: A0A2Y9H8Z9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

29088:LOC110573270
gene id: 29088:LOC110573270
uniprot id: A0A8M1M1U2
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

29088:MYH15
gene id: 29088:MYH15
uniprot id: A0A8M1MNK3
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:RSL24D1
gene id: 29088:RSL24D1
uniprot id: A0A2Y9HCX2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

29088:PPP1R14B
gene id: 29088:PPP1R14B
uniprot id: A0A2Y9GS66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Inhibitor of PPP1CA.
messages: Membrane

29088:ZNF330
gene id: 29088:ZNF330
uniprot id: A0A2Y9GB49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOA36 family.
messages: centromere
messages: nucleolus

29088:POLM
gene id: 29088:POLM
uniprot id: A0A2Y9I5U7
uniprot id: A0A2Y9I661
uniprot id: A0A2Y9I6N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ).
messages: Nucleus

29088:C16H19orf12
gene id: 29088:C16H19orf12
uniprot id: A0A2Y9HYE1
uniprot id: A0A2Y9HYI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

29088:LOC110574371
gene id: 29088:LOC110574371
uniprot id: A0A2Y9GL89
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:PAQR4
gene id: 29088:PAQR4
uniprot id: A0A2Y9HQ63
uniprot id: A0A2Y9HQA5
uniprot id: A0A8M1MB24
uniprot id: A0A8M1MEJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

29088:TULP3
gene id: 29088:TULP3
uniprot id: A0A2Y9H3X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

29088:DCBLD2
gene id: 29088:DCBLD2
uniprot id: A0A2Y9GWR0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:TOR1B
gene id: 29088:TOR1B
uniprot id: A0A2Y9H6Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Endoplasmic reticulum lumen

29088:GALNT12
gene id: 29088:GALNT12
uniprot id: A0A2Y9HBZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

29088:B4GALNT2
gene id: 29088:B4GALNT2
uniprot id: A0A2Y9I829
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

29088:KIF20B
gene id: 29088:KIF20B
uniprot id: A0A2Y9HVT0
uniprot id: A0A8M1MF53
uniprot id: A0A8M1MF83
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:CTF1
gene id: 29088:CTF1
uniprot id: A0A8M1MEP8
uniprot id: A0A8M1MJJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

29088:BLOC1S1
gene id: 29088:BLOC1S1
uniprot id: A0A2Y9GUC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BLOC1S1 family.
messages: Lysosome membrane
messages: May negatively regulate aerobic respiration through mitochondrial protein lysine-acetylation. May counteract the action of the deacetylase SIRT3 by acetylating and regulating proteins of the mitochondrial respiratory chain including ATP5F1A and NDUFA9.
messages: Mitochondrion intermembrane space

29088:ETF1
gene id: 29088:ETF1
uniprot id: A0A2Y9I5L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

29088:KLHL21
gene id: 29088:KLHL21
uniprot id: A0A2Y9GQT7
names: Subcellular Location Annotation
messages: spindle

29088:LOC110584665
gene id: 29088:LOC110584665
uniprot id: A0A8M1MUX3
uniprot id: A0A8M1MWP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

29088:MTFMT
gene id: 29088:MTFMT
uniprot id: A0A2Y9HCT2
names: Similarity
messages: Belongs to the Fmt family.

29088:ACTR8
gene id: 29088:ACTR8
uniprot id: A0A2Y9HGW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP8 subfamily.
messages: Chromosome
messages: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.
messages: Nucleus
messages: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
messages: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

29088:BACE1
gene id: 29088:BACE1
uniprot id: A0A2Y9HR86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Endosome
messages: Membrane
messages: Membrane raft
messages: Recycling endosome
messages: trans-Golgi network

29088:CGAS
gene id: 29088:CGAS
uniprot id: A0A2Y9HBQ0
names: Similarity
messages: Belongs to the mab-21 family.

29088:LOC110586231
gene id: 29088:LOC110586231
uniprot id: A0A8M1MNG4
names: Similarity
messages: Belongs to the peptidase C14A family.

29088:LOC110587807
gene id: 29088:LOC110587807
uniprot id: A0A8M1MDP6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

29088:ATG101
gene id: 29088:ATG101
uniprot id: A0A2Y9IDT3
names: Similarity
messages: Belongs to the ATG101 family.

29088:LOC110581150
gene id: 29088:LOC110581150
uniprot id: A0A2Y9H4M1
uniprot id: A0A2Y9HBB1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC123323171
gene id: 29088:LOC123323171
uniprot id: A0A8M1MPP4
names: Function
names: Similarity
messages: Belongs to the SAA family.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.

29088:UTP18
gene id: 29088:UTP18
uniprot id: A0A2Y9IFL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat UTP18 family.
messages: nucleolus

29088:PLXNA2
gene id: 29088:PLXNA2
uniprot id: A0A2Y9GGC9
uniprot id: A0A8M1MNC1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:IRGQ
gene id: 29088:IRGQ
uniprot id: A0A2Y9GCS9
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

29088:ATP9A
gene id: 29088:ATP9A
uniprot id: A0A2Y9GQL3
uniprot id: A0A8M1MQR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

29088:NUTM1
gene id: 29088:NUTM1
uniprot id: A0A2Y9HHF0
names: Similarity
messages: Belongs to the NUT family.

29088:AMOTL2
gene id: 29088:AMOTL2
uniprot id: A0A2Y9G6A9
uniprot id: A0A2Y9G8S2
names: Similarity
messages: Belongs to the angiomotin family.

29088:ACADM
gene id: 29088:ACADM
uniprot id: A0A2Y9G422
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Mitochondrion matrix

29088:TACR1
gene id: 29088:TACR1
uniprot id: A0A2Y9HT02
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane

29088:PLXNA4
gene id: 29088:PLXNA4
uniprot id: A0A2Y9H9W0
uniprot id: A0A2Y9H9X6
uniprot id: A0A2Y9HGH4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:S100G
gene id: 29088:S100G
uniprot id: A0A2Y9GGH8
names: Similarity
messages: Belongs to the S-100 family.

29088:ATP6V0B
gene id: 29088:ATP6V0B
uniprot id: A0A2Y9GQ92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: clathrin-coated vesicle membrane

29088:SELENOS
gene id: 29088:SELENOS
uniprot id: A0A2Y9GF59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenoprotein S family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination.
messages: Membrane

29088:ACAP2
gene id: 29088:ACAP2
uniprot id: A0A2Y9H8P8
uniprot id: A0A8M1MSY6
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

29088:ZDHHC23
gene id: 29088:ZDHHC23
uniprot id: A0A2Y9H8Q3
uniprot id: A0A2Y9HEH2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

29088:PTCH1
gene id: 29088:PTCH1
uniprot id: A0A8M1MU45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

29088:LOC110586492
gene id: 29088:LOC110586492
uniprot id: A0A2Y9HL34
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion membrane

29088:LOC110589695
gene id: 29088:LOC110589695
uniprot id: A0A8M1MP13
names: Similarity
messages: Belongs to the GroES chaperonin family.

29088:LOC110571954
gene id: 29088:LOC110571954
uniprot id: A0A2Y9GCN8
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:B3GALT5
gene id: 29088:B3GALT5
uniprot id: A0A2Y9G9M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:B4GALT5
gene id: 29088:B4GALT5
uniprot id: A0A2Y9GQX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

29088:AREG
gene id: 29088:AREG
uniprot id: A0A2Y9I769
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:SLC9A3
gene id: 29088:SLC9A3
uniprot id: A0A2Y9GU23
uniprot id: A0A2Y9GU84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Recycling endosome membrane

29088:DCTD
gene id: 29088:DCTD
uniprot id: A0A2Y9HJX1
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

29088:PDYN
gene id: 29088:PDYN
uniprot id: A0A2Y9H4X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opioid activity, it is 700 times more potent than Leu-enkephalin.
messages: Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.
messages: Leumorphin has a typical opioid activity and may have anti-apoptotic effect.
messages: Secreted

29088:TAF1A
gene id: 29088:TAF1A
uniprot id: A0A2Y9HR53
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B, TAF1C and TAF1D. In the complex interacts directly with TBP, TAF1A and TAF1B. Interaction of the SL1/TIF-IB subunits with TBP excludes interaction of TBP with the transcription factor IID (TFIID) subunits.
messages: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.
messages: Nucleus

29088:GLRA3
gene id: 29088:GLRA3
uniprot id: A0A2Y9HS63
uniprot id: A0A2Y9HXI8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

29088:GSDMB
gene id: 29088:GSDMB
uniprot id: A0A2Y9IF75
names: Similarity
messages: Belongs to the gasdermin family.

29088:ADRB2
gene id: 29088:ADRB2
uniprot id: A0A2Y9HM00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily.
messages: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
messages: Cell membrane
messages: Early endosome
messages: Golgi apparatus
messages: Membrane

29088:SIX4
gene id: 29088:SIX4
uniprot id: A0A2Y9I6J9
names: Subcellular Location Annotation
messages: Nucleus

29088:CXXC5
gene id: 29088:CXXC5
uniprot id: A0A2Y9I126
uniprot id: A0A2Y9I5J4
names: Subcellular Location Annotation
messages: Cytoplasm

29088:LOC110573972
gene id: 29088:LOC110573972
uniprot id: A0A8M1MET3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

29088:TMSB10
gene id: 29088:TMSB10
uniprot id: A0A2Y9HUZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

29088:LOC110582361
gene id: 29088:LOC110582361
uniprot id: A0A8M1MIP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GST superfamily. Pi family.
messages: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
messages: Cytoplasm
messages: Homodimer.
messages: Mitochondrion
messages: Nucleus

29088:TMEM134
gene id: 29088:TMEM134
uniprot id: A0A2Y9GNG6
uniprot id: A0A2Y9GU70
uniprot id: A0A8M1MRE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Membrane

29088:PIWIL4
gene id: 29088:PIWIL4
uniprot id: A0A2Y9G9A9
names: Similarity
messages: Belongs to the argonaute family.

29088:MAN2B1
gene id: 29088:MAN2B1
uniprot id: A0A2Y9IFR3
uniprot id: A0A8M1ML52
uniprot id: A0A8M1MT46
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

29088:CACNG3
gene id: 29088:CACNG3
uniprot id: A0A2Y9GTB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

29088:SLC25A33
gene id: 29088:SLC25A33
uniprot id: A0A2Y9GIU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:GJC3
gene id: 29088:GJC3
uniprot id: A0A2Y9G9N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

29088:DCLRE1C
gene id: 29088:DCLRE1C
uniprot id: A0A2Y9HLA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

29088:NEK7
gene id: 29088:NEK7
uniprot id: A0A2Y9GH21
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:PANX3
gene id: 29088:PANX3
uniprot id: A0A2Y9HKM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

29088:PSMB11
gene id: 29088:PSMB11
uniprot id: A0A2Y9HPH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

29088:NR1D1
gene id: 29088:NR1D1
uniprot id: A0A2Y9I8Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

29088:TMEM242
gene id: 29088:TMEM242
uniprot id: A0A2Y9HAJ8
uniprot id: A0A2Y9HGL6
uniprot id: A0A2Y9HH91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM242 family.
messages: Membrane

29088:RGN
gene id: 29088:RGN
uniprot id: A0A2Y9G743
uniprot id: A0A2Y9G7G4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm
messages: Monomer.

29088:SLC35D1
gene id: 29088:SLC35D1
uniprot id: A0A2Y9GD87
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110581396
gene id: 29088:LOC110581396
uniprot id: A0A2Y9HC81
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110580760
gene id: 29088:LOC110580760
uniprot id: A0A8M1MF03
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:BTLA
gene id: 29088:BTLA
uniprot id: A0A2Y9H9A6
names: Subcellular Location Annotation
messages: Cell membrane

29088:FAN1
gene id: 29088:FAN1
uniprot id: A0A2Y9GBF0
uniprot id: A0A2Y9GBH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

29088:LOC110574104
gene id: 29088:LOC110574104
uniprot id: A0A2Y9GKC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOR1AIP family.
messages: Membrane

29088:ITGA4
gene id: 29088:ITGA4
uniprot id: A0A2Y9I8S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

29088:TMEM145
gene id: 29088:TMEM145
uniprot id: A0A8M1MY55
uniprot id: A0A8M1MZI3
names: Subcellular Location Annotation
messages: Membrane

29088:GTF2H1
gene id: 29088:GTF2H1
uniprot id: A0A2Y9GUR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

29088:HOXB6
gene id: 29088:HOXB6
uniprot id: A0A2Y9IBP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

29088:PANX2
gene id: 29088:PANX2
uniprot id: A0A8M1MF32
uniprot id: A0A8M1MLH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

29088:SNX2
gene id: 29088:SNX2
uniprot id: A0A2Y9I0V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium

29088:ZSCAN1
gene id: 29088:ZSCAN1
uniprot id: A0A8M1M2R9
names: Subcellular Location Annotation
messages: Nucleus

29088:CTC1
gene id: 29088:CTC1
uniprot id: A0A2Y9HL78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTC1 family.
messages: Nucleus
messages: telomere

29088:ACTRT2
gene id: 29088:ACTRT2
uniprot id: A0A2Y9GNZ3
names: Similarity
messages: Belongs to the actin family.

29088:CMTM3
gene id: 29088:CMTM3
uniprot id: A0A2Y9IEI3
names: Subcellular Location Annotation
messages: Membrane

29088:VPS37A
gene id: 29088:VPS37A
uniprot id: A0A2Y9HE12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

29088:MED17
gene id: 29088:MED17
uniprot id: A0A2Y9G783
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

29088:EPHB3
gene id: 29088:EPHB3
uniprot id: A0A8M1MBZ5
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110576112
gene id: 29088:LOC110576112
uniprot id: A0A8M1MNS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:MCM8
gene id: 29088:MCM8
uniprot id: A0A2Y9GZ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

29088:UNC13B
gene id: 29088:UNC13B
uniprot id: A0A8M1MRV7
uniprot id: A0A8M1MV34
names: Subcellular Location Annotation
messages: Cytoplasm

29088:CD55
gene id: 29088:CD55
uniprot id: A0A2Y9GGY5
uniprot id: A0A2Y9GH20
uniprot id: A0A2Y9GH30
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:RCE1
gene id: 29088:RCE1
uniprot id: A0A2Y9GPN6
uniprot id: A0A2Y9GPW2
uniprot id: A0A2Y9GQ04
uniprot id: A0A2Y9GTR1
uniprot id: A0A2Y9GVH3
uniprot id: A0A8M1MRC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:HMGCL
gene id: 29088:HMGCL
uniprot id: A0A2Y9GKR7
uniprot id: A0A2Y9GL13
uniprot id: A0A8M1MBE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMG-CoA lyase family.
messages: Homodimer; disulfide-linked. Can also form homotetramers.
messages: Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

29088:KATNAL1
gene id: 29088:KATNAL1
uniprot id: A0A2Y9G4H1
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit. Interacts with ASPM; the katanin complex formation KATNA1:KATNB1 is required for the association of ASPM. Interacts with dynein and NDEL1. Associates with the E3 ligase complex containing DYRK2, EDD/UBR5, DDB1 and DCAF1 proteins (EDVP complex). Interacts with KLHL42 (via the kelch domains). Interacts with CUL3; the interaction is enhanced by KLHL42. Interacts with KATNB1 and KATNBL1. Interacts with CAMSAP2 and CAMSAP3; leading to regulate the length of CAMSAP-decorated microtubule stretches.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
messages: Cytoplasm
messages: Interacts with KATNB1 and KATNBL1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Midbody
messages: Phosphorylation by DYRK2 triggers ubiquitination and subsequent degradation.
messages: Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays.
messages: The N-terminus is sufficient for interaction with microtubules, although high affinity binding to microtubules also requires an intact C-terminal domain and ATP, which promotes oligomerization.
messages: Ubiquitinated by the BCR(KLHL42) E3 ubiquitin ligase complex, leading to its proteasomal degradation. Ubiquitinated by the EDVP E3 ligase complex and subsequently targeted for proteasomal degradation.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

29088:LOC110571813
gene id: 29088:LOC110571813
uniprot id: A0A8M1M878
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.

29088:USP1
gene id: 29088:USP1
uniprot id: A0A2Y9GD55
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

29088:PRPS1L1
gene id: 29088:PRPS1L1
uniprot id: A0A2Y9H1H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

29088:IL18
gene id: 29088:IL18
uniprot id: A0A2Y9HKK1
uniprot id: A0A2Y9HRB9
uniprot id: A0A2Y9HS94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-1 family.
messages: Cytoplasm
messages: Forms a ternary complex with ligand-binding receptor subunit IL18R1 and signaling receptor subunit IL18RAP at the plasma membrane. Mature IL18 first binds to IL18R1 forming a low affinity binary complex, which then interacts with IL18RAP to form a high affinity ternary complex that signals inside the cell. Interacts with cargo receptor TMED10; the interaction mediates the translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and thereby secretion.
messages: Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle.
messages: Pro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
messages: Secreted

29088:TMEM234
gene id: 29088:TMEM234
uniprot id: A0A2Y9GPQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM234 family.
messages: Membrane

29088:VCAM1
gene id: 29088:VCAM1
uniprot id: A0A2Y9H9K2
names: Subcellular Location Annotation
messages: Cell membrane

29088:F2
gene id: 29088:F2
uniprot id: A0A2Y9GMM8
names: Caution
names: Function
names: Similarity
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.

29088:LOC110570363
gene id: 29088:LOC110570363
uniprot id: A0A2Y9G5A0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.

29088:CCND3
gene id: 29088:CCND3
uniprot id: A0A2Y9HD34
uniprot id: A0A8M1MKQ7
names: Similarity
messages: Belongs to the cyclin family.

29088:TNNT3
gene id: 29088:TNNT3
uniprot id: A0A2Y9GNL8
uniprot id: A0A2Y9GNP5
uniprot id: A0A2Y9GNX3
uniprot id: A0A2Y9GUD2
uniprot id: A0A8M1MNC3
uniprot id: A0A8M1MNC7
uniprot id: A0A8M1MNC9
uniprot id: A0A8M1MND2
uniprot id: A0A8M1MND4
uniprot id: A0A8M1MND9
uniprot id: A0A8M1MQA2
uniprot id: A0A8M1MQA7
uniprot id: A0A8M1MQB2
uniprot id: A0A8M1MRL9
uniprot id: A0A8M1MRM4
uniprot id: A0A8M1MRM9
uniprot id: A0A8M1MXB3
uniprot id: A0A8M1MXB6
uniprot id: A0A8M1MXC0
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

29088:ASIC4
gene id: 29088:ASIC4
uniprot id: A0A2Y9I4G9
uniprot id: A0A8M1M665
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

29088:LOC110577179
gene id: 29088:LOC110577179
uniprot id: A0A8M1MTD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

29088:CCL16
gene id: 29088:CCL16
uniprot id: A0A2Y9I8K8
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

29088:LOC110583215
gene id: 29088:LOC110583215
uniprot id: A0A8M1MKW9
uniprot id: A0A8M1MRF5
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

29088:ZDHHC7
gene id: 29088:ZDHHC7
uniprot id: A0A2Y9I7J4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

29088:MRPS17
gene id: 29088:MRPS17
uniprot id: A0A2Y9HX58
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

29088:PPM1K
gene id: 29088:PPM1K
uniprot id: A0A2Y9I914
names: Similarity
messages: Belongs to the PP2C family.

29088:GRIN2A
gene id: 29088:GRIN2A
uniprot id: A0A2Y9HPZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

29088:LOC110582581
gene id: 29088:LOC110582581
uniprot id: A0A2Y9H9H5
names: Similarity
messages: Belongs to the SPIN/STSY family.

29088:POSTN
gene id: 29088:POSTN
uniprot id: A0A2Y9G4R4
uniprot id: A0A2Y9G4T3
uniprot id: A0A2Y9G4T8
uniprot id: A0A2Y9G796
uniprot id: A0A2Y9G7A1
uniprot id: A0A2Y9G8D5
uniprot id: A0A8M1M6K8
uniprot id: A0A8M1M906
names: Subcellular Location Annotation
messages: extracellular matrix

29088:LOC110573740
gene id: 29088:LOC110573740
uniprot id: A0A2Y9GFY7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ABCB6
gene id: 29088:ABCB6
uniprot id: A0A2Y9I3C8
uniprot id: A0A2Y9I3L1
uniprot id: A0A8M1M8K4
uniprot id: A0A8M1MEB6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Late endosome membrane
messages: Lysosome membrane
messages: Melanosome membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: extracellular exosome
messages: multivesicular body membrane

29088:LOC110591479
gene id: 29088:LOC110591479
uniprot id: A0A2Y9HYY8
uniprot id: A0A8M1M776
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

29088:DIPK1C
gene id: 29088:DIPK1C
uniprot id: A0A2Y9GRK6
names: Similarity
messages: Belongs to the DIPK family.

29088:RNF170
gene id: 29088:RNF170
uniprot id: A0A2Y9GID5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:LOC110591726
gene id: 29088:LOC110591726
uniprot id: A0A8M1MIZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Peroxisome matrix
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.

29088:LOC110570042
gene id: 29088:LOC110570042
uniprot id: A0A8M1M969
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Mitochondrion inner membrane

29088:LOC110585312
gene id: 29088:LOC110585312
uniprot id: A0A2Y9HNK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LYVE1
gene id: 29088:LYVE1
uniprot id: A0A2Y9GW06
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:IL17RD
gene id: 29088:IL17RD
uniprot id: A0A2Y9HGF2
names: Subcellular Location Annotation
messages: Membrane

29088:HYAL2
gene id: 29088:HYAL2
uniprot id: A0A2Y9GTV7
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

29088:POLR3B
gene id: 29088:POLR3B
uniprot id: A0A2Y9GVK7
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

29088:GPC3
gene id: 29088:GPC3
uniprot id: A0A2Y9GL76
uniprot id: A0A8M1M587
uniprot id: A0A8M1M8Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

29088:COPS8
gene id: 29088:COPS8
uniprot id: A0A2Y9G6I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN8 family.
messages: Cytoplasm
messages: Nucleus

29088:NTF4
gene id: 29088:NTF4
uniprot id: A0A2Y9GHF9
names: Similarity
messages: Belongs to the NGF-beta family.

29088:CITED1
gene id: 29088:CITED1
uniprot id: A0A2Y9GDP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

29088:TXNRD1
gene id: 29088:TXNRD1
uniprot id: A0A2Y9GUW7
uniprot id: A0A2Y9GUX2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

29088:HPX
gene id: 29088:HPX
uniprot id: A0A2Y9GU39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hemopexin family.
messages: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
messages: Secreted

29088:EXT2
gene id: 29088:EXT2
uniprot id: A0A2Y9GP56
uniprot id: A0A2Y9GPG9
uniprot id: A0A2Y9GUY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:LOXHD1
gene id: 29088:LOXHD1
uniprot id: A0A2Y9GS22
uniprot id: A0A8M1MWI0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:MYOC
gene id: 29088:MYOC
uniprot id: A0A2Y9GJZ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:F13B
gene id: 29088:F13B
uniprot id: A0A2Y9GGF1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:APEX2
gene id: 29088:APEX2
uniprot id: A0A2Y9HWS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Cytoplasm
messages: Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
messages: Mitochondrion
messages: Nucleus
messages: Probably binds two magnesium or manganese ions per subunit.

29088:LRRC8A
gene id: 29088:LRRC8A
uniprot id: A0A2Y9HD03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

29088:CAVIN3
gene id: 29088:CAVIN3
uniprot id: A0A2Y9GQ78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

29088:IFNGR1
gene id: 29088:IFNGR1
uniprot id: A0A8M1ML02
names: Similarity
messages: Belongs to the type II cytokine receptor family.

29088:YAE1
gene id: 29088:YAE1
uniprot id: A0A2Y9IAR6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:BOD1
gene id: 29088:BOD1
uniprot id: A0A2Y9HR81
uniprot id: A0A2Y9HXP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BOD1 family.
messages: centrosome
messages: kinetochore

29088:MAPK8IP2
gene id: 29088:MAPK8IP2
uniprot id: A0A2Y9H231
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JIP scaffold family.
messages: Cytoplasm

29088:CDCA7
gene id: 29088:CDCA7
uniprot id: A0A2Y9I4F6
uniprot id: A0A2Y9I8P2
uniprot id: A0A2Y9IB28
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:PHETA2
gene id: 29088:PHETA2
uniprot id: A0A2Y9H210
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Forms homodimers and heterodimers with PHETA. Interacts with OCRL and INPP5B.
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

29088:PTPN13
gene id: 29088:PTPN13
uniprot id: A0A8M1M4Q8
uniprot id: A0A8M1M510
uniprot id: A0A8M1M759
uniprot id: A0A8M1M8M8
uniprot id: A0A8M1MCT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.
messages: cytoskeleton

29088:PDP2
gene id: 29088:PDP2
uniprot id: A0A2Y9I6X5
names: Similarity
messages: Belongs to the PP2C family.

29088:TMEFF2
gene id: 29088:TMEFF2
uniprot id: A0A2Y9I4S7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:WNT9B
gene id: 29088:WNT9B
uniprot id: A0A2Y9G5B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

29088:MCEE
gene id: 29088:MCEE
uniprot id: A0A2Y9GF49
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

29088:ABCC4
gene id: 29088:ABCC4
uniprot id: A0A2Y9HJ38
uniprot id: A0A2Y9HJ41
uniprot id: A0A2Y9HQE1
names: Subcellular Location Annotation
messages: Membrane

29088:TMEM170A
gene id: 29088:TMEM170A
uniprot id: A0A2Y9IAZ1
uniprot id: A0A8M1MW80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

29088:UBE2D1
gene id: 29088:UBE2D1
uniprot id: A0A2Y9HUL6
uniprot id: A0A2Y9HZG5
uniprot id: A0A2Y9I0Y5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

29088:LETM1
gene id: 29088:LETM1
uniprot id: A0A8M1M537
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LETM1 family.
messages: Membrane
messages: Mitochondrion inner membrane

29088:NDFIP1
gene id: 29088:NDFIP1
uniprot id: A0A2Y9I7U4
uniprot id: A0A8M1MPH5
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

29088:BNIP3
gene id: 29088:BNIP3
uniprot id: A0A2Y9I6J0
uniprot id: A0A8M1MHN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

29088:LOC110584754
gene id: 29088:LOC110584754
uniprot id: A0A8M1MIF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:ARCN1
gene id: 29088:ARCN1
uniprot id: A0A2Y9HQU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

29088:EML5
gene id: 29088:EML5
uniprot id: A0A2Y9G969
uniprot id: A0A8M1MJT3
uniprot id: A0A8M1MN56
names: Function
names: Similarity
messages: Belongs to the WD repeat EMAP family.
messages: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.

29088:STRN4
gene id: 29088:STRN4
uniprot id: A0A2Y9GD71
uniprot id: A0A2Y9GDB7
uniprot id: A0A2Y9GDD2
uniprot id: A0A8M1MY65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

29088:DRAM1
gene id: 29088:DRAM1
uniprot id: A0A2Y9GZM6
names: Subcellular Location Annotation
messages: Membrane

29088:XPO7
gene id: 29088:XPO7
uniprot id: A0A2Y9HS16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

29088:UPK1B
gene id: 29088:UPK1B
uniprot id: A0A2Y9HEK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

29088:LOC110576470
gene id: 29088:LOC110576470
uniprot id: A0A2Y9GTZ3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110586645
gene id: 29088:LOC110586645
uniprot id: A0A8M1MJ43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the S-100 family.
messages: Facilitates the differentiation and the cornification of keratinocytes.
messages: Homodimer; disulfide-linked.

29088:LAMA1
gene id: 29088:LAMA1
uniprot id: A0A2Y9GRL5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

29088:LCN2
gene id: 29088:LCN2
uniprot id: A0A2Y9H6G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

29088:SMU1
gene id: 29088:SMU1
uniprot id: A0A2Y9H727
uniprot id: A0A2Y9HCP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SMU1 family.
messages: Nucleus speckle

29088:PRMT7
gene id: 29088:PRMT7
uniprot id: A0A2Y9I9Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
messages: Nucleus
messages: cytosol

29088:NCL
gene id: 29088:NCL
uniprot id: A0A2Y9H304
uniprot id: A0A2Y9H814
uniprot id: A0A8M1M692
names: Function
names: Subcellular Location Annotation
messages: Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.
messages: nucleolus

29088:VWCE
gene id: 29088:VWCE
uniprot id: A0A2Y9GMY8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:MUL1
gene id: 29088:MUL1
uniprot id: A0A2Y9GPE7
names: Subcellular Location Annotation
messages: Membrane

29088:FAM135B
gene id: 29088:FAM135B
uniprot id: A0A2Y9H2C6
names: Similarity
messages: Belongs to the FAM135 family.

29088:KCNC2
gene id: 29088:KCNC2
uniprot id: A0A2Y9G5D4
uniprot id: A0A2Y9G5D6
uniprot id: A0A2Y9G5E1
uniprot id: A0A2Y9G5U2
uniprot id: A0A2Y9G7W1
uniprot id: A0A2Y9G907
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110585318
gene id: 29088:LOC110585318
uniprot id: A0A8M1MLP3
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6A family.

29088:GPR20
gene id: 29088:GPR20
uniprot id: A0A2Y9GYU4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:ATAD1
gene id: 29088:ATAD1
uniprot id: A0A2Y9HJD7
uniprot id: A0A2Y9HJD8
uniprot id: A0A2Y9HQP3
names: Similarity
messages: Belongs to the AAA ATPase family.

29088:LOC110591290
gene id: 29088:LOC110591290
uniprot id: A0A2Y9HWD6
names: Similarity
messages: Belongs to the NAC-beta family.

29088:ATG9B
gene id: 29088:ATG9B
uniprot id: A0A2Y9HH13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

29088:NDUFV1
gene id: 29088:NDUFV1
uniprot id: A0A2Y9GU77
uniprot id: A0A8M1MP41
uniprot id: A0A8M1MSD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

29088:NRG2
gene id: 29088:NRG2
uniprot id: A0A2Y9I0Q5
uniprot id: A0A2Y9I107
uniprot id: A0A2Y9I175
uniprot id: A0A2Y9I5P3
uniprot id: A0A2Y9I7N4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:LOC110592993
gene id: 29088:LOC110592993
uniprot id: A0A8M1MXL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs. Binds with high affinity to IPO4. Interacts with DDIT3.
messages: Cytoplasm
messages: May play a role during erythropoiesis through regulation of transcription factor DDIT3.
messages: Nucleus
messages: nucleolus

29088:LOC110583090
gene id: 29088:LOC110583090
uniprot id: A0A8M1MHC8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

29088:EIF1B
gene id: 29088:EIF1B
uniprot id: A0A2Y9IC60
uniprot id: A0A2Y9IGF1
names: Similarity
messages: Belongs to the SUI1 family.

29088:PFKM
gene id: 29088:PFKM
uniprot id: A0A2Y9I936
uniprot id: A0A2Y9IDK5
uniprot id: A0A8M1MBZ3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:FRG1
gene id: 29088:FRG1
uniprot id: A0A2Y9HK91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRG1 family.
messages: Cajal body
messages: nucleolus

29088:RHBDF1
gene id: 29088:RHBDF1
uniprot id: A0A2Y9HQN1
uniprot id: A0A2Y9HR00
uniprot id: A0A2Y9HR33
uniprot id: A0A2Y9HVX1
uniprot id: A0A2Y9HXG2
uniprot id: A0A2Y9HXG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

29088:VIM
gene id: 29088:VIM
uniprot id: A0A2Y9HSR8
names: Similarity
messages: Belongs to the intermediate filament family.

29088:EBF2
gene id: 29088:EBF2
uniprot id: A0A2Y9HRW8
uniprot id: A0A2Y9HSC5
uniprot id: A0A2Y9HSD1
uniprot id: A0A2Y9HX92
uniprot id: A0A8M1M7P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

29088:RGR
gene id: 29088:RGR
uniprot id: A0A2Y9HW29
uniprot id: A0A2Y9I0U5
uniprot id: A0A2Y9I2G3
names: Subcellular Location Annotation
messages: Membrane

29088:AP3M1
gene id: 29088:AP3M1
uniprot id: A0A2Y9HZ37
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

29088:SLC12A2
gene id: 29088:SLC12A2
uniprot id: A0A2Y9I8J6
uniprot id: A0A8M1MGR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

29088:GALR2
gene id: 29088:GALR2
uniprot id: A0A2Y9GBR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

29088:LOC110589976
gene id: 29088:LOC110589976
uniprot id: A0A2Y9HXP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PET117 family.
messages: Mitochondrion

29088:SLC44A5
gene id: 29088:SLC44A5
uniprot id: A0A2Y9G7S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

29088:EEF1A1
gene id: 29088:EEF1A1
uniprot id: A0A2Y9HH84
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

29088:NTRK2
gene id: 29088:NTRK2
uniprot id: A0A2Y9G3J4
uniprot id: A0A2Y9G640
uniprot id: A0A8M1MU90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

29088:SLC2A6
gene id: 29088:SLC2A6
uniprot id: A0A2Y9HBT6
uniprot id: A0A8M1MRT2
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

29088:SND1
gene id: 29088:SND1
uniprot id: A0A8M1MQ22
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs.

29088:CAMK2N2
gene id: 29088:CAMK2N2
uniprot id: A0A2Y9H9U0
names: Similarity
messages: Belongs to the CAMK2N family.

29088:LOC123325487
gene id: 29088:LOC123325487
uniprot id: A0A8M1MKJ7
names: Similarity
messages: Belongs to the histone H3 family.

29088:TEAD4
gene id: 29088:TEAD4
uniprot id: A0A2Y9H4B0
uniprot id: A0A2Y9H4B1
uniprot id: A0A2Y9H4D0
uniprot id: A0A2Y9HB03
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

29088:TPO
gene id: 29088:TPO
uniprot id: A0A2Y9HNT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prostaglandin G/H synthase family.
messages: Interacts with DUOX1, DUOX2 and CYBA.
messages: Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:PIK3CG
gene id: 29088:PIK3CG
uniprot id: A0A2Y9GHI7
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

29088:ROGDI
gene id: 29088:ROGDI
uniprot id: A0A2Y9HQG9
uniprot id: A0A2Y9HQT8
uniprot id: A0A2Y9HX99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rogdi family.
messages: Presynapse
messages: Vesicle
messages: synaptic vesicle

29088:CD46
gene id: 29088:CD46
uniprot id: A0A8M1MG04
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:B9D2
gene id: 29088:B9D2
uniprot id: A0A8M1MXV5
names: Subcellular Location Annotation
messages: cilium basal body

29088:LOC110577202
gene id: 29088:LOC110577202
uniprot id: A0A8M1MQK6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

29088:ATP4A
gene id: 29088:ATP4A
uniprot id: A0A2Y9I4I5
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Membrane

29088:NAB1
gene id: 29088:NAB1
uniprot id: A0A2Y9I460
uniprot id: A0A2Y9I4R3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

29088:CD151
gene id: 29088:CD151
uniprot id: A0A2Y9H393
uniprot id: A0A2Y9H9W9
uniprot id: A0A2Y9H9X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

29088:JRK
gene id: 29088:JRK
uniprot id: A0A2Y9H4I4
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110592685
gene id: 29088:LOC110592685
uniprot id: A0A8M1MQJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light intermediate chain family.
messages: Cytoplasm

29088:ANXA9
gene id: 29088:ANXA9
uniprot id: A0A2Y9GWY8
uniprot id: A0A2Y9H104
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

29088:HS3ST2
gene id: 29088:HS3ST2
uniprot id: A0A2Y9GTF1
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

29088:ALOX12
gene id: 29088:ALOX12
uniprot id: A0A2Y9HEX4
uniprot id: A0A2Y9HF10
uniprot id: A0A2Y9HF16
uniprot id: A0A2Y9HFC1
uniprot id: A0A2Y9HLA9
uniprot id: A0A2Y9HLD6
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:TAF5
gene id: 29088:TAF5
uniprot id: A0A2Y9HUP3
uniprot id: A0A8M1MP24
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

29088:CNKSR1
gene id: 29088:CNKSR1
uniprot id: A0A2Y9GPJ9
uniprot id: A0A8M1M7K6
names: Similarity
messages: Belongs to the CNKSR family.

29088:MACO1
gene id: 29088:MACO1
uniprot id: A0A2Y9GMU7
uniprot id: A0A8M1M7K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Plays a role in the regulation of neuronal activity.
messages: Rough endoplasmic reticulum membrane

29088:TSC22D2
gene id: 29088:TSC22D2
uniprot id: A0A2Y9GR41
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

29088:DDAH2
gene id: 29088:DDAH2
uniprot id: A0A2Y9HM16
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

29088:DENND5A
gene id: 29088:DENND5A
uniprot id: A0A2Y9GP78
uniprot id: A0A8M1MPL7
uniprot id: A0A8M1MRH5
uniprot id: A0A8M1MSV5
uniprot id: A0A8M1MY03
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:RFX1
gene id: 29088:RFX1
uniprot id: A0A8M1MIN3
names: Subcellular Location Annotation
messages: Nucleus

29088:DLGAP4
gene id: 29088:DLGAP4
uniprot id: A0A2Y9GZB8
uniprot id: A0A2Y9GZH0
uniprot id: A0A2Y9GZH2
uniprot id: A0A2Y9GZH3
uniprot id: A0A2Y9H3X7
uniprot id: A0A2Y9H5V9
names: Similarity
messages: Belongs to the SAPAP family.

29088:TRIM36
gene id: 29088:TRIM36
uniprot id: A0A2Y9I233
names: Subcellular Location Annotation
messages: cytoskeleton

29088:SLC26A6
gene id: 29088:SLC26A6
uniprot id: A0A2Y9GTP2
uniprot id: A0A2Y9GTQ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:TUBGCP6
gene id: 29088:TUBGCP6
uniprot id: A0A2Y9GVD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: centrosome

29088:EIF2B4
gene id: 29088:EIF2B4
uniprot id: A0A2Y9HP52
uniprot id: A0A2Y9HVS4
uniprot id: A0A8M1MM46
uniprot id: A0A8M1MP42
uniprot id: A0A8M1MQE7
uniprot id: A0A8M1MWC7
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

29088:VEGFC
gene id: 29088:VEGFC
uniprot id: A0A2Y9HE41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

29088:NCAPH2
gene id: 29088:NCAPH2
uniprot id: A0A2Y9GVE4
uniprot id: A0A2Y9GZD4
uniprot id: A0A8M1MBK2
uniprot id: A0A8M1MBK7
uniprot id: A0A8M1MBQ5
uniprot id: A0A8M1MDU2
uniprot id: A0A8M1MF82
uniprot id: A0A8M1MK38
names: Similarity
messages: Belongs to the CND2 H2 (condensin-2 subunit 2) family.

29088:GRHL2
gene id: 29088:GRHL2
uniprot id: A0A2Y9GYS5
uniprot id: A0A2Y9H328
uniprot id: A0A2Y9H516
names: Subcellular Location Annotation
messages: Nucleus

29088:ACE
gene id: 29088:ACE
uniprot id: A0A2Y9G4W0
uniprot id: A0A2Y9G4X1
uniprot id: A0A8M1MV05
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.

29088:SGMS1
gene id: 29088:SGMS1
uniprot id: A0A2Y9HJM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

29088:LOC110588331
gene id: 29088:LOC110588331
uniprot id: A0A8M1MWK0
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

29088:LOC110591142
gene id: 29088:LOC110591142
uniprot id: A0A8M1MGZ1
uniprot id: A0A8M1MJ20
uniprot id: A0A8M1MKD8
uniprot id: A0A8M1MQV0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

29088:ACTL9
gene id: 29088:ACTL9
uniprot id: A0A2Y9IB09
names: Similarity
messages: Belongs to the actin family.

29088:TMEM150C
gene id: 29088:TMEM150C
uniprot id: A0A2Y9I9B0
names: Subcellular Location Annotation
messages: Membrane

29088:SS18
gene id: 29088:SS18
uniprot id: A0A2Y9GR97
uniprot id: A0A2Y9GRC3
uniprot id: A0A2Y9GRC8
names: Similarity
messages: Belongs to the SS18 family.

29088:COQ10B
gene id: 29088:COQ10B
uniprot id: A0A8M1M6A9
uniprot id: A0A8M1M8F6
uniprot id: A0A8M1M9V2
uniprot id: A0A8M1ME67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

29088:GTF2A1L
gene id: 29088:GTF2A1L
uniprot id: A0A2Y9HYT6
uniprot id: A0A2Y9I3L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

29088:PATL1
gene id: 29088:PATL1
uniprot id: A0A2Y9GTH8
names: Similarity
messages: Belongs to the PAT1 family.

29088:KCNMB1
gene id: 29088:KCNMB1
uniprot id: A0A2Y9HVJ2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KCNMB (TC 8.A.14.1) family.
messages: Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB per KCNMA1 tetramer.
messages: Membrane
messages: N-glycosylated.
messages: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

29088:ALDH3B2
gene id: 29088:ALDH3B2
uniprot id: A0A2Y9GNU1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

29088:DUSP29
gene id: 29088:DUSP29
uniprot id: A0A2Y9I0Y4
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

29088:LOC123323213
gene id: 29088:LOC123323213
uniprot id: A0A8M1M059
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galanin family.
messages: Hypothalamic neuropeptide which binds to the G-protein-coupled galanin receptors (GALR1, GALR2 and GALR3). Involved in a large number of putative physiological functions in CNS homeostatic processes, including the regulation of gonadotropin-releasing hormone secretion.
messages: Secreted

29088:SLC23A3
gene id: 29088:SLC23A3
uniprot id: A0A2Y9I442
names: Subcellular Location Annotation
messages: Membrane

29088:SH3BP5L
gene id: 29088:SH3BP5L
uniprot id: A0A2Y9H4M7
uniprot id: A0A2Y9HBB7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

29088:PLOD2
gene id: 29088:PLOD2
uniprot id: A0A2Y9HL87
uniprot id: A0A2Y9HLF6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

29088:CDCA7L
gene id: 29088:CDCA7L
uniprot id: A0A2Y9H1T2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:CELSR2
gene id: 29088:CELSR2
uniprot id: A0A2Y9H264
uniprot id: A0A2Y9H279
uniprot id: A0A2Y9H8Q9
uniprot id: A0A8M1M9G3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor that may have an important role in cell/cell signaling during nervous system formation.

29088:LOC110580245
gene id: 29088:LOC110580245
uniprot id: A0A8M1MI22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110574524
gene id: 29088:LOC110574524
uniprot id: A0A2Y9GIG8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110586807
gene id: 29088:LOC110586807
uniprot id: A0A2Y9HMD3
names: Subcellular Location Annotation
messages: Nucleus

29088:USP37
gene id: 29088:USP37
uniprot id: A0A8M1MEA6
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

29088:LOC110586591
gene id: 29088:LOC110586591
uniprot id: A0A8M1MAD4
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

29088:LOC110584777
gene id: 29088:LOC110584777
uniprot id: A0A8M1MSZ1
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

29088:LOC110589213
gene id: 29088:LOC110589213
uniprot id: A0A2Y9HUY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

29088:SOAT2
gene id: 29088:SOAT2
uniprot id: A0A2Y9GYX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:TM9SF3
gene id: 29088:TM9SF3
uniprot id: A0A2Y9I0S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

29088:ABCA6
gene id: 29088:ABCA6
uniprot id: A0A2Y9G521
names: Subcellular Location Annotation
messages: Membrane

29088:SYNDIG1L
gene id: 29088:SYNDIG1L
uniprot id: A0A2Y9G8H5
names: Similarity
messages: Belongs to the CD225/Dispanin family.

29088:ELL3
gene id: 29088:ELL3
uniprot id: A0A8M1MIQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

29088:LOC110593574
gene id: 29088:LOC110593574
uniprot id: A0A2Y9IGK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:NUPR1
gene id: 29088:NUPR1
uniprot id: A0A2Y9HW58
names: Similarity
messages: Belongs to the NUPR family.

29088:LOC110580985
gene id: 29088:LOC110580985
uniprot id: A0A8M1MCT2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Component of the 40S small ribosomal subunit.

29088:LOC110578090
gene id: 29088:LOC110578090
uniprot id: A0A8M1MBV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

29088:FUT2
gene id: 29088:FUT2
uniprot id: A0A8M1M0A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 11 family.
messages: Golgi stack membrane
messages: Membrane

29088:TDO2
gene id: 29088:TDO2
uniprot id: A0A2Y9HX86
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:TMEM167B
gene id: 29088:TMEM167B
uniprot id: A0A2Y9H2E4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:DTD1
gene id: 29088:DTD1
uniprot id: A0A2Y9HXG6
uniprot id: A0A2Y9HXR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

29088:LOC110586648
gene id: 29088:LOC110586648
uniprot id: A0A2Y9HLH7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:LOC110580531
gene id: 29088:LOC110580531
uniprot id: A0A2Y9H2U0
names: Similarity
messages: Belongs to the SCC3 family.

29088:PPP2R5B
gene id: 29088:PPP2R5B
uniprot id: A0A2Y9GTW7
uniprot id: A0A8M1MPN0
uniprot id: A0A8M1MRJ0
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

29088:NUSAP1
gene id: 29088:NUSAP1
uniprot id: A0A8M1MKD9
uniprot id: A0A8M1MKE2
uniprot id: A0A8M1MME7
uniprot id: A0A8M1MMF2
uniprot id: A0A8M1MNQ6
uniprot id: A0A8M1MUH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUSAP family.
messages: Cytoplasm

29088:LOC110571335
gene id: 29088:LOC110571335
uniprot id: A0A2Y9GBF8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

29088:ADGRB1
gene id: 29088:ADGRB1
uniprot id: A0A8M1MH33
names: Subcellular Location Annotation
messages: Membrane

29088:BID
gene id: 29088:BID
uniprot id: A0A2Y9H373
uniprot id: A0A8M1MAV3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion outer membrane

29088:ME3
gene id: 29088:ME3
uniprot id: A0A8M1MRE7
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

29088:GSDMD
gene id: 29088:GSDMD
uniprot id: A0A2Y9H355
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

29088:LOC110575797
gene id: 29088:LOC110575797
uniprot id: A0A2Y9GRP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SMIM7
gene id: 29088:SMIM7
uniprot id: A0A2Y9GNB8
names: Similarity
messages: Belongs to the SMIM7 family.

29088:DNAH2
gene id: 29088:DNAH2
uniprot id: A0A8M1MWC2
names: Similarity
messages: Belongs to the dynein heavy chain family.

29088:UBN1
gene id: 29088:UBN1
uniprot id: A0A2Y9HQB0
uniprot id: A0A2Y9HV82
uniprot id: A0A2Y9HWR9
names: Similarity
messages: Belongs to the ubinuclein family.

29088:TMEM267
gene id: 29088:TMEM267
uniprot id: A0A8M1MIH3
names: Subcellular Location Annotation
messages: Membrane

29088:SLC66A1
gene id: 29088:SLC66A1
uniprot id: A0A2Y9GPD4
names: Subcellular Location Annotation
messages: Membrane

29088:KCTD10
gene id: 29088:KCTD10
uniprot id: A0A2Y9I5E3
uniprot id: A0A2Y9I5L9
names: Similarity
messages: Belongs to the BACURD family.

29088:KRT15
gene id: 29088:KRT15
uniprot id: A0A2Y9GEM6
names: Similarity
messages: Belongs to the intermediate filament family.

29088:LOC123324563
gene id: 29088:LOC123324563
uniprot id: A0A8M1M876
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:PRICKLE2
gene id: 29088:PRICKLE2
uniprot id: A0A2Y9HGV1
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

29088:TARS2
gene id: 29088:TARS2
uniprot id: A0A2Y9H109
uniprot id: A0A8M1MC21
uniprot id: A0A8M1MGM2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

29088:LOC110585535
gene id: 29088:LOC110585535
uniprot id: A0A2Y9HHW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SERPINB10
gene id: 29088:SERPINB10
uniprot id: A0A2Y9GRB5
names: Similarity
messages: Belongs to the serpin family.

29088:LOC110573347
gene id: 29088:LOC110573347
uniprot id: A0A2Y9GEK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:TRPV4
gene id: 29088:TRPV4
uniprot id: A0A2Y9I5D4
uniprot id: A0A2Y9ICQ9
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110585698
gene id: 29088:LOC110585698
uniprot id: A0A8M1MGF9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

29088:FGFR1OP2
gene id: 29088:FGFR1OP2
uniprot id: A0A2Y9H3F4
uniprot id: A0A2Y9H8I9
uniprot id: A0A2Y9HA43
uniprot id: A0A8M1MIX5
names: Similarity
messages: Belongs to the SIKE family.

29088:LOC110591078
gene id: 29088:LOC110591078
uniprot id: A0A8M1MG79
names: Similarity
messages: Belongs to the NAC-beta family.

29088:PUSL1
gene id: 29088:PUSL1
uniprot id: A0A8M1MCM6
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

29088:BCL7B
gene id: 29088:BCL7B
uniprot id: A0A2Y9I366
uniprot id: A0A8M1MB33
uniprot id: A0A8M1MBB0
names: Similarity
messages: Belongs to the BCL7 family.

29088:GIPC2
gene id: 29088:GIPC2
uniprot id: A0A2Y9G431
names: Similarity
messages: Belongs to the GIPC family.

29088:LOC110570473
gene id: 29088:LOC110570473
uniprot id: A0A2Y9G581
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

29088:PPP1CB
gene id: 29088:PPP1CB
uniprot id: A0A2Y9HP77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: nucleolus
messages: nucleoplasm

29088:STEAP3
gene id: 29088:STEAP3
uniprot id: A0A2Y9HPA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

29088:STYXL2
gene id: 29088:STYXL2
uniprot id: A0A2Y9GGU6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

29088:LOC110582536
gene id: 29088:LOC110582536
uniprot id: A0A8M1M7R0
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

29088:P2RX6
gene id: 29088:P2RX6
uniprot id: A0A2Y9H2L9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

29088:CDPF1
gene id: 29088:CDPF1
uniprot id: A0A2Y9GVB9
names: Similarity
messages: Belongs to the CDPF1 family.

29088:TIGD5
gene id: 29088:TIGD5
uniprot id: A0A2Y9GYI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tigger transposable element derived protein family.
messages: Nucleus

29088:LIN28B
gene id: 29088:LIN28B
uniprot id: A0A2Y9HBZ0
names: Similarity
messages: Belongs to the lin-28 family.

29088:POLRMT
gene id: 29088:POLRMT
uniprot id: A0A8M1M9D9
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

29088:LOC110583370
gene id: 29088:LOC110583370
uniprot id: A0A8M1MHS9
names: Similarity
messages: Belongs to the sorting nexin family.

29088:ST6GAL1
gene id: 29088:ST6GAL1
uniprot id: A0A2Y9H8T8
uniprot id: A0A2Y9HFJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

29088:DLK2
gene id: 29088:DLK2
uniprot id: A0A2Y9HEI2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:PTX3
gene id: 29088:PTX3
uniprot id: A0A2Y9I3C5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LPIN3
gene id: 29088:LPIN3
uniprot id: A0A2Y9H0J5
names: Similarity
messages: Belongs to the lipin family.

29088:LOC110592157
gene id: 29088:LOC110592157
uniprot id: A0A8M1M874
names: Similarity
messages: Belongs to the PDCD5 family.

29088:GRM3
gene id: 29088:GRM3
uniprot id: A0A2Y9H1K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

29088:IRF8
gene id: 29088:IRF8
uniprot id: A0A2Y9I2J8
names: Subcellular Location Annotation
messages: Nucleus

29088:B4GALT4
gene id: 29088:B4GALT4
uniprot id: A0A2Y9H908
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

29088:PTPRM
gene id: 29088:PTPRM
uniprot id: A0A8M1MYX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Cell membrane
messages: Membrane

29088:LOC110576384
gene id: 29088:LOC110576384
uniprot id: A0A8M1MQF9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

29088:SYNDIG1
gene id: 29088:SYNDIG1
uniprot id: A0A2Y9I2J4
names: Similarity
messages: Belongs to the CD225/Dispanin family.

29088:ANG
gene id: 29088:ANG
uniprot id: A0A8M1MM53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

29088:LOC110577114
gene id: 29088:LOC110577114
uniprot id: A0A2Y9GS52
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

29088:ACTL7A
gene id: 29088:ACTL7A
uniprot id: A0A2Y9H730
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Golgi apparatus
messages: May play an important role in formation and fusion of Golgi-derived vesicles during acrosome biogenesis.
messages: Nucleus
messages: cytoskeleton

29088:NT5C2
gene id: 29088:NT5C2
uniprot id: A0A2Y9HVM2
uniprot id: A0A2Y9HW46
uniprot id: A0A2Y9HW72
uniprot id: A0A2Y9I0W4
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

29088:PBX4
gene id: 29088:PBX4
uniprot id: A0A8M1MKV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

29088:SYF2
gene id: 29088:SYF2
uniprot id: A0A2Y9GMU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: May be part of a spliceosome complex.
messages: Nucleus

29088:VLDLR
gene id: 29088:VLDLR
uniprot id: A0A2Y9HK84
uniprot id: A0A2Y9HKH3
uniprot id: A0A8M1MSD5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:GARS1
gene id: 29088:GARS1
uniprot id: A0A2Y9H1Q7
uniprot id: A0A2Y9H6L2
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

29088:MMP15
gene id: 29088:MMP15
uniprot id: A0A8M1MVV3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

29088:NIPAL1
gene id: 29088:NIPAL1
uniprot id: A0A2Y9I0D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

29088:EYA4
gene id: 29088:EYA4
uniprot id: A0A2Y9HB68
uniprot id: A0A2Y9HBI7
uniprot id: A0A2Y9HHA4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

29088:RYR2
gene id: 29088:RYR2
uniprot id: A0A2Y9HJI5
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

29088:TSPAN13
gene id: 29088:TSPAN13
uniprot id: A0A2Y9H1A8
names: Subcellular Location Annotation
messages: Membrane

29088:ATP5MC1
gene id: 29088:ATP5MC1
uniprot id: A0A2Y9IBK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

29088:GLG1
gene id: 29088:GLG1
uniprot id: A0A8M1M7V4
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Golgi outpost
messages: Membrane
messages: microtubule organizing center

29088:CDC34
gene id: 29088:CDC34
uniprot id: A0A2Y9IFE6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

29088:GFRA1
gene id: 29088:GFRA1
uniprot id: A0A8M1MFD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane

29088:CHRND
gene id: 29088:CHRND
uniprot id: A0A2Y9H322
uniprot id: A0A2Y9H825
uniprot id: A0A2Y9H9Q2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:MTCL1
gene id: 29088:MTCL1
uniprot id: A0A8M1MSQ0
uniprot id: A0A8M1MUJ1
uniprot id: A0A8M1MVX0
uniprot id: A0A8M1MYS3
names: Similarity
messages: Belongs to the SOGA family.

29088:MON1A
gene id: 29088:MON1A
uniprot id: A0A2Y9GTX1
uniprot id: A0A8M1MIW4
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

29088:FGF3
gene id: 29088:FGF3
uniprot id: A0A2Y9GP24
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

29088:FUT10
gene id: 29088:FUT10
uniprot id: A0A2Y9HDW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Predominantly fucosylates the innermost N-acetyl glucosamine (GlcNAc) residue in biantennary N-glycan acceptors.

29088:OSBPL1A
gene id: 29088:OSBPL1A
uniprot id: A0A2Y9GR92
uniprot id: A0A2Y9GWT0
names: Similarity
messages: Belongs to the OSBP family.

29088:BRS3
gene id: 29088:BRS3
uniprot id: A0A2Y9GMF4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with C6orf89.
messages: Membrane

29088:LOC110583580
gene id: 29088:LOC110583580
uniprot id: A0A2Y9HI36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.
messages: Heterotetramer of two alpha and two beta chains.

29088:NOP53
gene id: 29088:NOP53
uniprot id: A0A2Y9GCZ0
uniprot id: A0A2Y9GHB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP53 family.
messages: May play a role in ribosome biogenesis.
messages: nucleolus
messages: nucleoplasm

29088:TAF15
gene id: 29088:TAF15
uniprot id: A0A2Y9I7L7
uniprot id: A0A2Y9IC22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

29088:LOC110591135
gene id: 29088:LOC110591135
uniprot id: A0A8M1MG76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

29088:TRAK2
gene id: 29088:TRAK2
uniprot id: A0A2Y9I9V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion

29088:KCNK3
gene id: 29088:KCNK3
uniprot id: A0A2Y9HVF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

29088:SPEM1
gene id: 29088:SPEM1
uniprot id: A0A2Y9HF25
names: Subcellular Location Annotation
messages: Membrane

29088:NAV2
gene id: 29088:NAV2
uniprot id: A0A8M1MP05
uniprot id: A0A8M1MSA5
uniprot id: A0A8M1MXR1
names: Similarity
messages: Belongs to the Nav/unc-53 family.

29088:SH3RF3
gene id: 29088:SH3RF3
uniprot id: A0A2Y9GAA6
names: Similarity
messages: Belongs to the SH3RF family.

29088:ZDHHC20
gene id: 29088:ZDHHC20
uniprot id: A0A2Y9G771
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

29088:SGF29
gene id: 29088:SGF29
uniprot id: A0A2Y9HWN8
names: Subcellular Location Annotation
messages: Nucleus

29088:GNG5
gene id: 29088:GNG5
uniprot id: A0A2Y9H7Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

29088:LOC110575895
gene id: 29088:LOC110575895
uniprot id: A0A8M1MP50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

29088:NEXMIF
gene id: 29088:NEXMIF
uniprot id: A0A2Y9GT97
names: Subcellular Location Annotation
messages: Nucleus

29088:TAS2R3
gene id: 29088:TAS2R3
uniprot id: A0A2Y9HAI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

29088:TRPC6
gene id: 29088:TRPC6
uniprot id: A0A8M1MRN4
names: Subcellular Location Annotation
messages: Membrane

29088:LOC123325104
gene id: 29088:LOC123325104
uniprot id: A0A8M1MHS0
names: Similarity
messages: Belongs to the GSK-3-binding protein family.

29088:LOC110586317
gene id: 29088:LOC110586317
uniprot id: A0A2Y9HKB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:REV3L
gene id: 29088:REV3L
uniprot id: A0A2Y9HID1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

29088:POLR3A
gene id: 29088:POLR3A
uniprot id: A0A2Y9HZN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

29088:RNF43
gene id: 29088:RNF43
uniprot id: A0A2Y9I7Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZNRF3 family.
messages: Cell membrane

29088:PIK3CD
gene id: 29088:PIK3CD
uniprot id: A0A2Y9GKH9
uniprot id: A0A2Y9GKL2
uniprot id: A0A2Y9GKS1
uniprot id: A0A2Y9GP77
uniprot id: A0A2Y9GQU8
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

29088:EXOC8
gene id: 29088:EXOC8
uniprot id: A0A2Y9HJ36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO84 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: growth cone
messages: perinuclear region

29088:LOC110577473
gene id: 29088:LOC110577473
uniprot id: A0A2Y9GZ22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:RSPO2
gene id: 29088:RSPO2
uniprot id: A0A2Y9GYE6
uniprot id: A0A2Y9GYF6
uniprot id: A0A2Y9H4Q6
names: Similarity
messages: Belongs to the R-spondin family.

29088:KAT7
gene id: 29088:KAT7
uniprot id: A0A2Y9I8E9
uniprot id: A0A2Y9I8N0
uniprot id: A0A2Y9I945
uniprot id: A0A8M1MVF5
uniprot id: A0A8M1MVF8
uniprot id: A0A8M1MX11
uniprot id: A0A8M1MXS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

29088:LOC110589882
gene id: 29088:LOC110589882
uniprot id: A0A2Y9HWZ2
uniprot id: A0A8M1MEY6
uniprot id: A0A8M1MLC1
names: Subcellular Location Annotation
messages: Nucleus

29088:RNF7
gene id: 29088:RNF7
uniprot id: A0A2Y9G8B1
uniprot id: A0A2Y9G9G8
uniprot id: A0A8M1MKA4
names: Similarity
messages: Belongs to the RING-box family.

29088:LOC110581808
gene id: 29088:LOC110581808
uniprot id: A0A2Y9H6S1
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

29088:PFKFB2
gene id: 29088:PFKFB2
uniprot id: A0A2Y9GGF8
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

29088:MRRF
gene id: 29088:MRRF
uniprot id: A0A2Y9H611
names: Function
names: Similarity
messages: Belongs to the RRF family.
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

29088:GPN1
gene id: 29088:GPN1
uniprot id: A0A2Y9HMP0
uniprot id: A0A2Y9HN47
uniprot id: A0A2Y9HT46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

29088:OSBPL11
gene id: 29088:OSBPL11
uniprot id: A0A2Y9H8G6
names: Similarity
messages: Belongs to the OSBP family.

29088:SLC30A1
gene id: 29088:SLC30A1
uniprot id: A0A2Y9GM03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

29088:SEMA3E
gene id: 29088:SEMA3E
uniprot id: A0A2Y9H127
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the semaphorin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:EIF4G1
gene id: 29088:EIF4G1
uniprot id: A0A2Y9H947
uniprot id: A0A2Y9H982
uniprot id: A0A2Y9H9D2
uniprot id: A0A2Y9HEZ8
uniprot id: A0A8M1MQ31
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

29088:PELI1
gene id: 29088:PELI1
uniprot id: A0A2Y9HT34
names: Function
names: Similarity
messages: Belongs to the pellino family.
messages: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

29088:MIXL1
gene id: 29088:MIXL1
uniprot id: A0A8M1ME53
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110585116
gene id: 29088:LOC110585116
uniprot id: A0A2Y9HGW5
names: Similarity
messages: Belongs to the bZIP family. C/EBP subfamily.

29088:ZNF503
gene id: 29088:ZNF503
uniprot id: A0A2Y9HUT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

29088:TNFSF10
gene id: 29088:TNFSF10
uniprot id: A0A2Y9I9T2
uniprot id: A0A8M1MDV6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tumor necrosis factor family.
messages: Homotrimer.
messages: Membrane
messages: Secreted

29088:XKR8
gene id: 29088:XKR8
uniprot id: A0A2Y9GJL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

29088:ENOPH1
gene id: 29088:ENOPH1
uniprot id: A0A2Y9I225
uniprot id: A0A2Y9I8T5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

29088:ASIC5
gene id: 29088:ASIC5
uniprot id: A0A2Y9HSU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

29088:GGT1
gene id: 29088:GGT1
uniprot id: A0A2Y9GW91
uniprot id: A0A2Y9H0N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

29088:TCF7
gene id: 29088:TCF7
uniprot id: A0A2Y9I5P7
uniprot id: A0A8M1MJ84
uniprot id: A0A8M1MPL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

29088:CDCP2
gene id: 29088:CDCP2
uniprot id: A0A8M1MAC3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:SERBP1
gene id: 29088:SERBP1
uniprot id: A0A2Y9G9P1
uniprot id: A0A2Y9G9S2
uniprot id: A0A2Y9GC91
uniprot id: A0A2Y9GDD7
names: Similarity
messages: Belongs to the SERBP1-HABP4 family.

29088:FKBP4
gene id: 29088:FKBP4
uniprot id: A0A2Y9HAC6
names: Subcellular Location Annotation
messages: Mitochondrion
messages: cytoskeleton
messages: cytosol

29088:LOC110578265
gene id: 29088:LOC110578265
uniprot id: A0A2Y9H238
uniprot id: A0A8M1MLK3
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

29088:PAX3
gene id: 29088:PAX3
uniprot id: A0A2Y9I4F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

29088:PRKAB2
gene id: 29088:PRKAB2
uniprot id: A0A2Y9GX47
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

29088:LOC110593715
gene id: 29088:LOC110593715
uniprot id: A0A2Y9I9W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: cytoskeleton

29088:PHC3
gene id: 29088:PHC3
uniprot id: A0A2Y9I2Y6
names: Subcellular Location Annotation
messages: Nucleus

29088:EHHADH
gene id: 29088:EHHADH
uniprot id: A0A2Y9H8Y2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

29088:S1PR2
gene id: 29088:S1PR2
uniprot id: A0A2Y9IHM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:RAB38
gene id: 29088:RAB38
uniprot id: A0A2Y9H799
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

29088:GATA4
gene id: 29088:GATA4
uniprot id: A0A2Y9HSM0
uniprot id: A0A2Y9HSM5
uniprot id: A0A8M1M420
names: Subcellular Location Annotation
messages: Nucleus

29088:ESRRA
gene id: 29088:ESRRA
uniprot id: A0A2Y9GN36
uniprot id: A0A2Y9GNF2
uniprot id: A0A2Y9GTV0
uniprot id: A0A8M1MPM3
uniprot id: A0A8M1MRI0
uniprot id: A0A8M1MSW0
uniprot id: A0A8M1MY06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

29088:DYNC1I2
gene id: 29088:DYNC1I2
uniprot id: A0A2Y9I5N0
uniprot id: A0A8M1M9B3
uniprot id: A0A8M1MAQ1
uniprot id: A0A8M1MF51
names: Similarity
messages: Belongs to the dynein intermediate chain family.

29088:SF3A3
gene id: 29088:SF3A3
uniprot id: A0A2Y9GJP8
uniprot id: A0A8M1MBJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3A3 family.
messages: Nucleus

29088:MAS1
gene id: 29088:MAS1
uniprot id: A0A2Y9HI16
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:FBN3
gene id: 29088:FBN3
uniprot id: A0A8M1M7Q6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibrillin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:SMC3
gene id: 29088:SMC3
uniprot id: A0A2Y9I0Z1
uniprot id: A0A2Y9I2L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement.
messages: Nucleus
messages: centromere

29088:OXR1
gene id: 29088:OXR1
uniprot id: A0A2Y9GYV2
uniprot id: A0A2Y9GYW9
uniprot id: A0A2Y9H374
names: Similarity
messages: Belongs to the OXR1 family.

29088:GPRIN1
gene id: 29088:GPRIN1
uniprot id: A0A8M1MPA2
names: Function
messages: May be involved in neurite outgrowth.

29088:SLC5A12
gene id: 29088:SLC5A12
uniprot id: A0A2Y9GUL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

29088:LPAR5
gene id: 29088:LPAR5
uniprot id: A0A2Y9H3S1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:TPPP3
gene id: 29088:TPPP3
uniprot id: A0A2Y9IBW8
names: Similarity
messages: Belongs to the TPPP family.

29088:SLIT3
gene id: 29088:SLIT3
uniprot id: A0A2Y9HPC2
uniprot id: A0A8M1MQP1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:DNAH8
gene id: 29088:DNAH8
uniprot id: A0A2Y9GSR9
names: Similarity
messages: Belongs to the dynein heavy chain family.

29088:LOC110574529
gene id: 29088:LOC110574529
uniprot id: A0A8M1MIJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SEMA4G
gene id: 29088:SEMA4G
uniprot id: A0A2Y9HVZ1
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC123326496
gene id: 29088:LOC123326496
uniprot id: A0A8M1MR87
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

29088:SELL
gene id: 29088:SELL
uniprot id: A0A2Y9GGT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the selectin/LECAM family.
messages: Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia.
messages: Cell membrane
messages: Interaction with SELPLG/PSGL1 and PODXL2 is required for promoting recruitment and rolling of leukocytes. This interaction is dependent on the sialyl Lewis X glycan modification of SELPLG and PODXL2, and tyrosine sulfation modifications of SELPLG. Sulfation on 'Tyr-51' of SELPLG is important for L-selectin binding.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:ADRA1B
gene id: 29088:ADRA1B
uniprot id: A0A2Y9HUJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane
messages: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
messages: caveola

29088:BTD
gene id: 29088:BTD
uniprot id: A0A2Y9G8H6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

29088:LYRM4
gene id: 29088:LYRM4
uniprot id: A0A2Y9HT82
names: Similarity
messages: Belongs to the complex I LYR family.

29088:TWSG1
gene id: 29088:TWSG1
uniprot id: A0A2Y9H784
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the twisted gastrulation protein family.
messages: Secreted

29088:KPNA1
gene id: 29088:KPNA1
uniprot id: A0A2Y9HG96
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

29088:REN
gene id: 29088:REN
uniprot id: A0A2Y9GWQ9
uniprot id: A0A2Y9GYA9
names: Similarity
messages: Belongs to the peptidase A1 family.

29088:HLF
gene id: 29088:HLF
uniprot id: A0A2Y9I7C9
uniprot id: A0A2Y9I7N3
uniprot id: A0A2Y9I867
uniprot id: A0A2Y9IC36
uniprot id: A0A2Y9IET6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

29088:NAT10
gene id: 29088:NAT10
uniprot id: A0A2Y9GP93
uniprot id: A0A2Y9GPD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with THUMPD1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

29088:GSG1L2
gene id: 29088:GSG1L2
uniprot id: A0A2Y9HLX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

29088:FTSJ3
gene id: 29088:FTSJ3
uniprot id: A0A2Y9G8T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Interacts with NIP7.
messages: Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation.
messages: nucleolus

29088:ADGRF5
gene id: 29088:ADGRF5
uniprot id: A0A2Y9HD00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

29088:CLDN20
gene id: 29088:CLDN20
uniprot id: A0A2Y9HBT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

29088:PHACTR2
gene id: 29088:PHACTR2
uniprot id: A0A2Y9HB99
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

29088:AHCYL2
gene id: 29088:AHCYL2
uniprot id: A0A2Y9HYK6
uniprot id: A0A2Y9I051
uniprot id: A0A8M1MU27
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

29088:LOC110584821
gene id: 29088:LOC110584821
uniprot id: A0A8M1MYY7
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

29088:TCTN1
gene id: 29088:TCTN1
uniprot id: A0A2Y9HRJ0
uniprot id: A0A2Y9HRY9
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

29088:TRIM54
gene id: 29088:TRIM54
uniprot id: A0A2Y9HNR5
names: Function
names: Subcellular Location Annotation
messages: May bind and stabilize microtubules during myotubes formation.
messages: Z line

29088:APOA2
gene id: 29088:APOA2
uniprot id: A0A7F3R6R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein A2 family.
messages: May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.
messages: Monomer. Interacts with NAXE and NDRG1.
messages: Secreted

29088:REC8
gene id: 29088:REC8
uniprot id: A0A2Y9HHR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

29088:KIDINS220
gene id: 29088:KIDINS220
uniprot id: A0A2Y9HP21
uniprot id: A0A8M1MM33
uniprot id: A0A8M1MM34
uniprot id: A0A8M1MP28
uniprot id: A0A8M1MQD6
uniprot id: A0A8M1MWB1
names: Function
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

29088:CEMIP2
gene id: 29088:CEMIP2
uniprot id: A0A2Y9HEC2
names: Similarity
messages: Belongs to the CEMIP family.

29088:CGA
gene id: 29088:CGA
uniprot id: A0A2Y9HBI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit alpha family.
messages: Heterodimer. The active hormones thyrotropin, lutropin and follitropin are heterodimers composed of CGA, a common alpha chain described here and a unique beta chain which confers their biological specificity to the hormones: TSHB for thyrotropin, LHB for lutropin and FSHB for follitropin.
messages: Secreted
messages: Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.

29088:AMOT
gene id: 29088:AMOT
uniprot id: A0A2Y9GSA5
names: Similarity
messages: Belongs to the angiomotin family.

29088:CHST1
gene id: 29088:CHST1
uniprot id: A0A2Y9GRI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

29088:THY1
gene id: 29088:THY1
uniprot id: A0A2Y9HK15
names: Subcellular Location Annotation
messages: Cell membrane

29088:LAMB3
gene id: 29088:LAMB3
uniprot id: A0A2Y9GGZ1
uniprot id: A0A2Y9GH27
uniprot id: A0A2Y9GKB0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:GNPDA1
gene id: 29088:GNPDA1
uniprot id: A0A2Y9I0A6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

29088:LOC110576605
gene id: 29088:LOC110576605
uniprot id: A0A2Y9GQL2
names: Similarity
messages: Belongs to the NAC-beta family.

29088:NR1H4
gene id: 29088:NR1H4
uniprot id: A0A2Y9GVG2
uniprot id: A0A2Y9GVJ5
uniprot id: A0A2Y9H1B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

29088:EWSR1
gene id: 29088:EWSR1
uniprot id: A0A2Y9ICS5
uniprot id: A0A8M1MWE9
uniprot id: A0A8M1MYW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

29088:DHDH
gene id: 29088:DHDH
uniprot id: A0A2Y9GCX7
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

29088:KIF2B
gene id: 29088:KIF2B
uniprot id: A0A2Y9IF39
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:TAS2R8
gene id: 29088:TAS2R8
uniprot id: A0A2Y9H3C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

29088:CRYBB3
gene id: 29088:CRYBB3
uniprot id: A0A2Y9IAC7
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

29088:LOC110587219
gene id: 29088:LOC110587219
uniprot id: A0A8M1MMZ9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

29088:LOC110589106
gene id: 29088:LOC110589106
uniprot id: A0A2Y9HUF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

29088:LOC110586304
gene id: 29088:LOC110586304
uniprot id: A0A2Y9HKK8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ATRX
gene id: 29088:ATRX
uniprot id: A0A2Y9G6G3
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

29088:ADAMTS13
gene id: 29088:ADAMTS13
uniprot id: A0A2Y9H6W0
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:LIPK
gene id: 29088:LIPK
uniprot id: A0A2Y9HQ82
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

29088:TAX1BP3
gene id: 29088:TAX1BP3
uniprot id: A0A2Y9I797
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: May regulate a number of protein-protein interactions by competing for PDZ domain binding sites.
messages: Nucleus

29088:CMTM8
gene id: 29088:CMTM8
uniprot id: A0A2Y9G6J4
names: Subcellular Location Annotation
messages: Membrane

29088:RPL7A
gene id: 29088:RPL7A
uniprot id: A0A2Y9H6M1
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

29088:THOC7
gene id: 29088:THOC7
uniprot id: A0A2Y9HM86
uniprot id: A0A2Y9HME7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC7 family.
messages: Nucleus
messages: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.

29088:AK3
gene id: 29088:AK3
uniprot id: A0A2Y9HEB8
uniprot id: A0A2Y9HEK2
uniprot id: A0A8M1MYK4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

29088:LOC110583988
gene id: 29088:LOC110583988
uniprot id: A0A8M1MJY2
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

29088:TGFBI
gene id: 29088:TGFBI
uniprot id: A0A2Y9I0M6
names: Subcellular Location Annotation
messages: extracellular matrix

29088:LOC110577796
gene id: 29088:LOC110577796
uniprot id: A0A2Y9H0B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

29088:LOC110581513
gene id: 29088:LOC110581513
uniprot id: A0A2Y9H625
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SPTY2D1
gene id: 29088:SPTY2D1
uniprot id: A0A2Y9GW73
uniprot id: A0A8M1MMZ6
names: Similarity
messages: Belongs to the SPT2 family.

29088:PPRC1
gene id: 29088:PPRC1
uniprot id: A0A2Y9HUP2
uniprot id: A0A2Y9I007
uniprot id: A0A8M1MDY8
uniprot id: A0A8M1ME35
names: Subcellular Location Annotation
messages: Nucleus

29088:CD38
gene id: 29088:CD38
uniprot id: A0A2Y9G7V0
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

29088:SLC35E4
gene id: 29088:SLC35E4
uniprot id: A0A2Y9I5K9
uniprot id: A0A8M1MT44
names: Subcellular Location Annotation
messages: Membrane

29088:HOXC9
gene id: 29088:HOXC9
uniprot id: A0A2Y9GTB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

29088:LOC110575151
gene id: 29088:LOC110575151
uniprot id: A0A2Y9GPE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

29088:SPNS3
gene id: 29088:SPNS3
uniprot id: A0A8M1MXL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

29088:HTT
gene id: 29088:HTT
uniprot id: A0A2Y9G6I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the huntingtin family.
messages: Cytoplasm
messages: May play a role in microtubule-mediated transport or vesicle function.
messages: Nucleus

29088:WDR55
gene id: 29088:WDR55
uniprot id: A0A2Y9I7V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR55 family.
messages: Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis.
messages: nucleolus

29088:LOC110589450
gene id: 29088:LOC110589450
uniprot id: A0A2Y9I249
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIII family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

29088:MEX3B
gene id: 29088:MEX3B
uniprot id: A0A2Y9GFG6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:ABCD2
gene id: 29088:ABCD2
uniprot id: A0A2Y9H880
uniprot id: A0A2Y9H9U7
names: Subcellular Location Annotation
messages: Membrane

29088:C7H5orf63
gene id: 29088:C7H5orf63
uniprot id: A0A2Y9I1G3
names: Similarity
messages: Belongs to the glutaredoxin family.

29088:CEP70
gene id: 29088:CEP70
uniprot id: A0A2Y9G6N0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Directly interacts with tubulin-gamma; this interaction determines centrosomal localization.
messages: Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle.
messages: centrosome

29088:VBP1
gene id: 29088:VBP1
uniprot id: A0A2Y9GGR8
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

29088:LOC123324831
gene id: 29088:LOC123324831
uniprot id: A0A8M1M9Y4
names: Similarity
messages: Belongs to the GAGE family.

29088:NKAIN4
gene id: 29088:NKAIN4
uniprot id: A0A2Y9G5R2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:IRF9
gene id: 29088:IRF9
uniprot id: A0A2Y9HPP0
uniprot id: A0A8M1MKE9
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110586616
gene id: 29088:LOC110586616
uniprot id: A0A8M1MK83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus

29088:PHB
gene id: 29088:PHB
uniprot id: A0A2Y9I8K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

29088:LOC110570898
gene id: 29088:LOC110570898
uniprot id: A0A2Y9G6J8
uniprot id: A0A2Y9G913
uniprot id: A0A2Y9GA41
names: Similarity
messages: Belongs to the PP2C family.

29088:MMP20
gene id: 29088:MMP20
uniprot id: A0A2Y9HR19
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

29088:DNM1
gene id: 29088:DNM1
uniprot id: A0A2Y9HCC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: Cytoplasm

29088:CCDC85B
gene id: 29088:CCDC85B
uniprot id: A0A2Y9GSD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

29088:GALNT1
gene id: 29088:GALNT1
uniprot id: A0A2Y9GV84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

29088:MSI2
gene id: 29088:MSI2
uniprot id: A0A2Y9I830
uniprot id: A0A2Y9I8U0
uniprot id: A0A8M1MWT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

29088:GATM
gene id: 29088:GATM
uniprot id: A0A2Y9HHX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the amidinotransferase family.
messages: Homodimer.
messages: Mitochondrion inner membrane
messages: Transamidinase that catalyzes the transfer of the amidino group of L-arginine onto the amino moiety of acceptor metabolites such as glycine, beta-alanine, gamma-aminobutyric acid (GABA) and taurine yielding the corresponding guanidine derivatives. Catalyzes the rate-limiting step of creatine biosynthesis, namely the transfer of the amidino group from L-arginine to glycine to generate guanidinoacetate, which is then methylated by GAMT to form creatine. Provides creatine as a source for ATP generation in tissues with high energy demands, in particular skeletal muscle, heart and brain.

29088:LOC110574849
gene id: 29088:LOC110574849
uniprot id: A0A2Y9GJJ4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

29088:LOC110571551
gene id: 29088:LOC110571551
uniprot id: A0A2Y9G8P4
names: Similarity
messages: Belongs to the GSKIP family.

29088:CARMIL2
gene id: 29088:CARMIL2
uniprot id: A0A2Y9I6N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

29088:LOC110571810
gene id: 29088:LOC110571810
uniprot id: A0A2Y9G9G4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

29088:CITED4
gene id: 29088:CITED4
uniprot id: A0A2Y9GK21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

29088:METTL8
gene id: 29088:METTL8
uniprot id: A0A2Y9I4B0
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

29088:NSUN2
gene id: 29088:NSUN2
uniprot id: A0A8M1MGG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: extracellular exosome

29088:SLC12A5
gene id: 29088:SLC12A5
uniprot id: A0A2Y9H4I8
uniprot id: A0A2Y9H6G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

29088:PTPRB
gene id: 29088:PTPRB
uniprot id: A0A2Y9G5G0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.

29088:NOVA2
gene id: 29088:NOVA2
uniprot id: A0A2Y9GCV9
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with PTBP2; the interaction is direct.
messages: Nucleus

29088:MAT2A
gene id: 29088:MAT2A
uniprot id: A0A2Y9HP18
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

29088:GTF2H3
gene id: 29088:GTF2H3
uniprot id: A0A2Y9HWI1
uniprot id: A0A2Y9HY64
uniprot id: A0A8M1MT15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
messages: Nucleus
messages: Part of a TFIID-containing RNA polymerase II pre-initiation complex that is composed of TBP and at least GTF2A1, GTF2A2, GTF2E1, GTF2E2, GTF2F1, GTF2H2, GTF2H3, GTF2H4, GTF2H5, GTF2B, TCEA1, ERCC2, ERCC3, TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Component of the 7-subunit TFIIH core complex composed of XPB/ERCC3, XPD/ERCC2, GTF2H1, GTF2H2, GTF2H3, GTF2H4 and GTF2H5, which is active in NER. The core complex associates with the 3-subunit CDK-activating kinase (CAK) module composed of CCNH/cyclin H, CDK7 and MNAT1 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription. Interacts with RARA; the interaction requires prior phosphorylation of RARA on 'Ser-369' which then enhances interaction of RARA with CDK7.

29088:BEGAIN
gene id: 29088:BEGAIN
uniprot id: A0A8M1MJF9
uniprot id: A0A8M1MJG0
uniprot id: A0A8M1MLH3
uniprot id: A0A8M1MMT5
names: Subcellular Location Annotation
messages: Membrane

29088:HMOX1
gene id: 29088:HMOX1
uniprot id: A0A2Y9GZS8
names: Similarity
messages: Belongs to the heme oxygenase family.

29088:CPEB4
gene id: 29088:CPEB4
uniprot id: A0A8M1MGS5
uniprot id: A0A8M1MGT4
uniprot id: A0A8M1MK75
uniprot id: A0A8M1MQN4
names: Similarity
messages: Belongs to the RRM CPEB family.

29088:LOC110585306
gene id: 29088:LOC110585306
uniprot id: A0A2Y9HHD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:EDN3
gene id: 29088:EDN3
uniprot id: A0A2Y9G357
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

29088:EIF4E
gene id: 29088:EIF4E
uniprot id: A0A2Y9GAP7
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

29088:FEZ2
gene id: 29088:FEZ2
uniprot id: A0A2Y9HNC5
uniprot id: A0A2Y9HNK9
uniprot id: A0A8M1MPM2
names: Similarity
messages: Belongs to the zygin family.

29088:KMT2A
gene id: 29088:KMT2A
uniprot id: A0A2Y9HKQ1
uniprot id: A0A8M1MPC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
messages: Nucleus

29088:LOC110589328
gene id: 29088:LOC110589328
uniprot id: A0A8M1MG08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

29088:TGFBR2
gene id: 29088:TGFBR2
uniprot id: A0A2Y9G9Z5
uniprot id: A0A8M1MYK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways.

29088:HOXB4
gene id: 29088:HOXB4
uniprot id: A0A2Y9I729
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

29088:UBE2D2
gene id: 29088:UBE2D2
uniprot id: A0A2Y9I5D3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

29088:LOC110582389
gene id: 29088:LOC110582389
uniprot id: A0A2Y9H8X0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:RUNDC3A
gene id: 29088:RUNDC3A
uniprot id: A0A2Y9GE34
uniprot id: A0A2Y9GE54
uniprot id: A0A2Y9GH34
names: Similarity
messages: Belongs to the RUNDC3 family.

29088:SMC1A
gene id: 29088:SMC1A
uniprot id: A0A2Y9I6F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

29088:INHBC
gene id: 29088:INHBC
uniprot id: A0A2Y9GUR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

29088:GCGR
gene id: 29088:GCGR
uniprot id: A0A8M1MU15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

29088:RNASEH1
gene id: 29088:RNASEH1
uniprot id: A0A2Y9HMT0
uniprot id: A0A2Y9HMT7
uniprot id: A0A2Y9HMZ0
uniprot id: A0A8M1MKX6
names: Function
names: Similarity
messages: Belongs to the RNase H family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

29088:AZGP1
gene id: 29088:AZGP1
uniprot id: A0A2Y9GA67
names: Similarity
messages: Belongs to the MHC class I family.

29088:LOC110590062
gene id: 29088:LOC110590062
uniprot id: A0A2Y9HXM6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

29088:AOC1
gene id: 29088:AOC1
uniprot id: A0A2Y9HAE0
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

29088:C6H10orf90
gene id: 29088:C6H10orf90
uniprot id: A0A2Y9I6N8
uniprot id: A0A2Y9IB47
uniprot id: A0A2Y9IDS2
names: Subcellular Location Annotation
messages: centrosome

29088:KCNC1
gene id: 29088:KCNC1
uniprot id: A0A2Y9GQK1
names: Subcellular Location Annotation
messages: Membrane

29088:UCN
gene id: 29088:UCN
uniprot id: A0A2Y9HU66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

29088:LSM7
gene id: 29088:LSM7
uniprot id: A0A2Y9IBA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

29088:HPD
gene id: 29088:HPD
uniprot id: A0A2Y9HWL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

29088:LOC110576654
gene id: 29088:LOC110576654
uniprot id: A0A2Y9GQR7
names: Similarity
names: Subunit
messages: Belongs to the TBP family.
messages: Binds TFIIA and TFIIB.

29088:RPS25
gene id: 29088:RPS25
uniprot id: A0A2Y9HJQ6
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS25 family.
messages: Component of the small ribosomal subunit.

29088:RPS19BP1
gene id: 29088:RPS19BP1
uniprot id: A0A2Y9GVU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AROS family.
messages: nucleolus

29088:GLIPR1L1
gene id: 29088:GLIPR1L1
uniprot id: A0A2Y9G5B4
names: Similarity
messages: Belongs to the CRISP family.

29088:TYR
gene id: 29088:TYR
uniprot id: A0A2Y9G6W8
uniprot id: A0A8M1MQI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

29088:TRHR
gene id: 29088:TRHR
uniprot id: A0A2Y9H4S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

29088:HAGH
gene id: 29088:HAGH
uniprot id: A0A2Y9HVD0
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

29088:TMEM183A
gene id: 29088:TMEM183A
uniprot id: A0A2Y9GSM4
uniprot id: A0A2Y9GST2
uniprot id: A0A8M1MEI7
uniprot id: A0A8M1MGP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM183 family.
messages: Membrane

29088:KDM5B
gene id: 29088:KDM5B
uniprot id: A0A2Y9GGZ4
uniprot id: A0A2Y9GLW3
uniprot id: A0A8M1MDC0
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

29088:LOC110579468
gene id: 29088:LOC110579468
uniprot id: A0A2Y9HUR8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

29088:LOC110589433
gene id: 29088:LOC110589433
uniprot id: A0A2Y9I234
names: Similarity
messages: Belongs to the synaptotagmin family.

29088:UNCX
gene id: 29088:UNCX
uniprot id: A0A2Y9GA25
names: Subcellular Location Annotation
messages: Nucleus

29088:TMEM178A
gene id: 29088:TMEM178A
uniprot id: A0A2Y9HNS8
names: Similarity
messages: Belongs to the TMEM178 family.

29088:SLC39A7
gene id: 29088:SLC39A7
uniprot id: A0A2Y9GMG3
uniprot id: A0A8M1MS65
names: Subcellular Location Annotation
messages: Membrane

29088:GNPDA2
gene id: 29088:GNPDA2
uniprot id: A0A2Y9I0A3
uniprot id: A0A2Y9I4T5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

29088:LOC110585813
gene id: 29088:LOC110585813
uniprot id: A0A2Y9HIL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:LPIN2
gene id: 29088:LPIN2
uniprot id: A0A2Y9GR99
names: Similarity
messages: Belongs to the lipin family.

29088:RRM1
gene id: 29088:RRM1
uniprot id: A0A2Y9I9J8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

29088:PDXK
gene id: 29088:PDXK
uniprot id: A0A2Y9G9W3
names: Similarity
messages: Belongs to the pyridoxine kinase family.

29088:MAP2K2
gene id: 29088:MAP2K2
uniprot id: A0A2Y9I9W3
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:CA9
gene id: 29088:CA9
uniprot id: A0A2Y9HCY4
uniprot id: A0A8M1MTK7
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

29088:KRR1
gene id: 29088:KRR1
uniprot id: A0A2Y9G5D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
messages: nucleolus

29088:YIPF6
gene id: 29088:YIPF6
uniprot id: A0A2Y9G9T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:MUS81
gene id: 29088:MUS81
uniprot id: A0A2Y9GU06
uniprot id: A0A8M1MQB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
messages: Interacts with EME1.
messages: Nucleus

29088:LOC110590581
gene id: 29088:LOC110590581
uniprot id: A0A8M1MMX8
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

29088:DPPA5
gene id: 29088:DPPA5
uniprot id: A0A2Y9HIQ5
names: Similarity
messages: Belongs to the KHDC1 family.

29088:LOC110585372
gene id: 29088:LOC110585372
uniprot id: A0A2Y9HHY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:CA4
gene id: 29088:CA4
uniprot id: A0A2Y9IEI8
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

29088:TMEM199
gene id: 29088:TMEM199
uniprot id: A0A2Y9I8A3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:ARL8B
gene id: 29088:ARL8B
uniprot id: A0A2Y9HFN7
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: spindle

29088:GOT1
gene id: 29088:GOT1
uniprot id: A0A2Y9I1W8
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

29088:ODR4
gene id: 29088:ODR4
uniprot id: A0A2Y9GGL9
names: Function
names: Similarity
messages: Belongs to the ODR-4 family.
messages: May play a role in the trafficking of a subset of G-protein coupled receptors.

29088:FOXK1
gene id: 29088:FOXK1
uniprot id: A0A8M1MDT2
names: Subcellular Location Annotation
messages: Nucleus

29088:GDA
gene id: 29088:GDA
uniprot id: A0A2Y9HE34
uniprot id: A0A8M1MST3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

29088:SLC39A6
gene id: 29088:SLC39A6
uniprot id: A0A8M1MVR5
names: Subcellular Location Annotation
messages: Membrane

29088:LOC123326186
gene id: 29088:LOC123326186
uniprot id: A0A8M1MQ11
names: Function
names: Similarity
messages: Belongs to the SAA family.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.

29088:DLD
gene id: 29088:DLD
uniprot id: A0A2Y9GHI0
uniprot id: A0A8M1MQU4
uniprot id: A0A8M1MU22
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.
messages: acrosome
messages: flagellum

29088:CLIC4
gene id: 29088:CLIC4
uniprot id: A0A8M1MCU1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

29088:SYT17
gene id: 29088:SYT17
uniprot id: A0A2Y9HPW3
uniprot id: A0A2Y9HQB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Membrane

29088:E2F8
gene id: 29088:E2F8
uniprot id: A0A2Y9GQF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

29088:NOS1
gene id: 29088:NOS1
uniprot id: A0A2Y9HWA3
uniprot id: A0A2Y9HXV5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.
messages: dendritic spine
messages: sarcolemma

29088:IER5L
gene id: 29088:IER5L
uniprot id: A0A8M1MUG6
names: Similarity
messages: Belongs to the IER family.

29088:VPS28
gene id: 29088:VPS28
uniprot id: A0A2Y9GYW8
uniprot id: A0A2Y9GZ70
names: Function
names: Similarity
messages: Belongs to the VPS28 family.
messages: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.

29088:P2RX3
gene id: 29088:P2RX3
uniprot id: A0A2Y9GN05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

29088:IL13RA2
gene id: 29088:IL13RA2
uniprot id: A0A2Y9GS91
names: Subcellular Location Annotation
messages: Membrane

29088:WNK2
gene id: 29088:WNK2
uniprot id: A0A8M1MTY8
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

29088:GPR68
gene id: 29088:GPR68
uniprot id: A0A2Y9G8F8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:DVL1
gene id: 29088:DVL1
uniprot id: A0A2Y9GKN8
names: Similarity
messages: Belongs to the DSH family.

29088:XKR4
gene id: 29088:XKR4
uniprot id: A0A2Y9GXH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

29088:LOC110579605
gene id: 29088:LOC110579605
uniprot id: A0A2Y9H044
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide.
messages: Secreted
messages: When bound to LPS, interacts (via C-terminus) with soluble and membrane-bound CD14.

29088:TUFM
gene id: 29088:TUFM
uniprot id: A0A2Y9HWW7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

29088:LOC110581203
gene id: 29088:LOC110581203
uniprot id: A0A2Y9H4S9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110586906
gene id: 29088:LOC110586906
uniprot id: A0A2Y9HMB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

29088:ZBTB8OS
gene id: 29088:ZBTB8OS
uniprot id: A0A2Y9GN37
uniprot id: A0A2Y9GPR5
uniprot id: A0A8M1M958
uniprot id: A0A8M1M9E7
uniprot id: A0A8M1MBJ1
uniprot id: A0A8M1MCX5
uniprot id: A0A8M1MHL2
names: Similarity
names: Subunit
messages: Belongs to the archease family.
messages: Component of the tRNA-splicing ligase complex.

29088:G6PC1
gene id: 29088:G6PC1
uniprot id: A0A2Y9GH72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

29088:NDST2
gene id: 29088:NDST2
uniprot id: A0A2Y9HU30
uniprot id: A0A2Y9HUK7
uniprot id: A0A2Y9HZF9
uniprot id: A0A2Y9I0Y2
uniprot id: A0A8M1MF37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

29088:SELENOM
gene id: 29088:SELENOM
uniprot id: A0A2Y9ICU8
names: Similarity
messages: Belongs to the selenoprotein M/F family.

29088:ATAT1
gene id: 29088:ATAT1
uniprot id: A0A2Y9HS56
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autoacetylation strongly increases tubulin acetylation.
messages: Belongs to the acetyltransferase ATAT1 family.
messages: Component of the BBSome complex. Interacts with AP2 alpha-adaptins, including AP2A2, but not with AP1 gamma-adaptin (AP1G1/AP1G2); this interaction is required for efficient alpha-tubulin acetylation, hence clathrin-coated pits are sites of microtubule acetylation.
messages: Cytoplasm
messages: Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly.
messages: axon
messages: clathrin-coated pit
messages: cytoskeleton
messages: focal adhesion
messages: spindle

29088:LOC110571126
gene id: 29088:LOC110571126
uniprot id: A0A8M1MRI6
uniprot id: A0A8M1MX84
names: Similarity
messages: Belongs to the SH3BGR family.

29088:CHL1
gene id: 29088:CHL1
uniprot id: A0A2Y9HFR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Cell membrane

29088:HPGD
gene id: 29088:HPGD
uniprot id: A0A2Y9HZ23
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29088:IGF2BP3
gene id: 29088:IGF2BP3
uniprot id: A0A2Y9H198
uniprot id: A0A2Y9H636
uniprot id: A0A2Y9H7U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: P-body
messages: Stress granule

29088:APH1A
gene id: 29088:APH1A
uniprot id: A0A2Y9GX04
uniprot id: A0A8M1M8H2
uniprot id: A0A8M1MC12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

29088:TRPV3
gene id: 29088:TRPV3
uniprot id: A0A2Y9IB91
uniprot id: A0A2Y9IDW9
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110586228
gene id: 29088:LOC110586228
uniprot id: A0A2Y9HQX2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:QRSL1
gene id: 29088:QRSL1
uniprot id: A0A2Y9HBD3
uniprot id: A0A2Y9HHG3
uniprot id: A0A2Y9HI38
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

29088:HRH3
gene id: 29088:HRH3
uniprot id: A0A2Y9G5V0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:FGF10
gene id: 29088:FGF10
uniprot id: A0A2Y9HRM9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

29088:CA5A
gene id: 29088:CA5A
uniprot id: A0A2Y9IEN1
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

29088:ACTR5
gene id: 29088:ACTR5
uniprot id: A0A2Y9H0D0
names: Similarity
messages: Belongs to the actin family.

29088:LOC110592261
gene id: 29088:LOC110592261
uniprot id: A0A2Y9IBW5
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

29088:SNX9
gene id: 29088:SNX9
uniprot id: A0A2Y9HHA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

29088:CDK5RAP2
gene id: 29088:CDK5RAP2
uniprot id: A0A8M1MVH8
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: centrosome

29088:JPH3
gene id: 29088:JPH3
uniprot id: A0A8M1M7R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:SLC25A22
gene id: 29088:SLC25A22
uniprot id: A0A2Y9H9L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:LOC123325700
gene id: 29088:LOC123325700
uniprot id: A0A8M1MTH2
names: Similarity
messages: Belongs to the serpin family.

29088:CMPK2
gene id: 29088:CMPK2
uniprot id: A0A2Y9HP40
names: Similarity
messages: Belongs to the thymidylate kinase family.

29088:TATDN3
gene id: 29088:TATDN3
uniprot id: A0A2Y9GLF9
uniprot id: A0A8M1MEM3
uniprot id: A0A8M1MER1
uniprot id: A0A8M1MGS6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

29088:LOC110576739
gene id: 29088:LOC110576739
uniprot id: A0A8M1MU32
names: Similarity
messages: Belongs to the NifU family.

29088:CCDC65
gene id: 29088:CCDC65
uniprot id: A0A2Y9IDW1
names: Subcellular Location Annotation
messages: flagellum axoneme

29088:PANX1
gene id: 29088:PANX1
uniprot id: A0A2Y9G6U7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: S-nitrosylation inhibits channel currents and ATP release.
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

29088:LOC123323163
gene id: 29088:LOC123323163
uniprot id: A0A8M1MNY7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

29088:PPT2
gene id: 29088:PPT2
uniprot id: A0A2Y9HM21
uniprot id: A0A2Y9HMF5
uniprot id: A0A2Y9HSL7
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

29088:SLC6A19
gene id: 29088:SLC6A19
uniprot id: A0A2Y9H001
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

29088:LOC110576408
gene id: 29088:LOC110576408
uniprot id: A0A2Y9GPR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:NUDC
gene id: 29088:NUDC
uniprot id: A0A2Y9GJK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudC family.
messages: Midbody
messages: spindle

29088:TMEM251
gene id: 29088:TMEM251
uniprot id: A0A2Y9GC35
uniprot id: A0A8M1MN23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LYSET family.
messages: Membrane

29088:HMMR
gene id: 29088:HMMR
uniprot id: A0A2Y9HHL6
uniprot id: A0A8M1MI53
uniprot id: A0A8M1MPV7
names: Subcellular Location Annotation
messages: spindle

29088:NOL12
gene id: 29088:NOL12
uniprot id: A0A2Y9GVQ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP17 family.
messages: Interacts with KIAA1191.
messages: nucleolus

29088:ADAMTS5
gene id: 29088:ADAMTS5
uniprot id: A0A2Y9G4D3
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:MPV17
gene id: 29088:MPV17
uniprot id: A0A2Y9HNE4
uniprot id: A0A8M1MLF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

29088:SLC17A9
gene id: 29088:SLC17A9
uniprot id: A0A2Y9G351
names: Subcellular Location Annotation
messages: Membrane

29088:MUSTN1
gene id: 29088:MUSTN1
uniprot id: A0A8M1M4D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MUSTANG family.
messages: Nucleus

29088:CNR1
gene id: 29088:CNR1
uniprot id: A0A2Y9HBN5
uniprot id: A0A2Y9HC29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for cannabinoids, including endocannabinoids (eCBs), such as N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG). Signaling typically involves reduction in cyclic AMP.
messages: Interacts (via C-terminus) with CNRIP1.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Presynapse
messages: Synapse
messages: axon

29088:DDIT4L
gene id: 29088:DDIT4L
uniprot id: A0A2Y9GDA6
names: Similarity
messages: Belongs to the DDIT4 family.

29088:MAP6
gene id: 29088:MAP6
uniprot id: A0A2Y9I9G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STOP family.
messages: cytoskeleton

29088:PPFIBP2
gene id: 29088:PPFIBP2
uniprot id: A0A2Y9GP38
uniprot id: A0A8M1MXV4
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

29088:MCM4
gene id: 29088:MCM4
uniprot id: A0A2Y9H3X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

29088:NME4
gene id: 29088:NME4
uniprot id: A0A2Y9HQJ6
names: Similarity
messages: Belongs to the NDK family.

29088:AKIRIN2
gene id: 29088:AKIRIN2
uniprot id: A0A2Y9HGT9
uniprot id: A0A8M1MHD8
uniprot id: A0A8M1MKR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

29088:KCNMA1
gene id: 29088:KCNMA1
uniprot id: A0A2Y9HUB8
uniprot id: A0A2Y9HUC5
uniprot id: A0A2Y9HUC9
uniprot id: A0A2Y9HUV7
uniprot id: A0A2Y9HUV9
uniprot id: A0A2Y9HUW1
uniprot id: A0A2Y9HUW4
uniprot id: A0A2Y9HUW6
uniprot id: A0A2Y9HUX1
uniprot id: A0A2Y9HUX6
uniprot id: A0A2Y9HZN5
uniprot id: A0A2Y9HZP0
uniprot id: A0A2Y9HZP5
uniprot id: A0A2Y9I177
uniprot id: A0A2Y9I182
uniprot id: A0A2Y9I187
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa1.1/KCNMA1 sub-subfamily.
messages: Membrane

29088:ROR2
gene id: 29088:ROR2
uniprot id: A0A8M1MR57
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:PUS7L
gene id: 29088:PUS7L
uniprot id: A0A2Y9I9X9
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

29088:CPVL
gene id: 29088:CPVL
uniprot id: A0A2Y9H1H4
uniprot id: A0A8M1MY97
names: Similarity
messages: Belongs to the peptidase S10 family.

29088:PEBP4
gene id: 29088:PEBP4
uniprot id: A0A2Y9HS77
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

29088:LOC110577356
gene id: 29088:LOC110577356
uniprot id: A0A8M1MHA8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ILF3
gene id: 29088:ILF3
uniprot id: A0A8M1MA68
uniprot id: A0A8M1MAB1
uniprot id: A0A8M1MAD0
uniprot id: A0A8M1MDZ5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:LOXL3
gene id: 29088:LOXL3
uniprot id: A0A2Y9HSY8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

29088:NUBPL
gene id: 29088:NUBPL
uniprot id: A0A8M1MTI2
names: Similarity
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.

29088:KREMEN2
gene id: 29088:KREMEN2
uniprot id: A0A2Y9HQB6
uniprot id: A0A2Y9HQN5
uniprot id: A0A2Y9HVK1
uniprot id: A0A2Y9HX42
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.

29088:LOC110585307
gene id: 29088:LOC110585307
uniprot id: A0A2Y9HNJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC123326402
gene id: 29088:LOC123326402
uniprot id: A0A8M1MQL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ependymin family.
messages: Binds anionic lipids and gangliosides at acidic pH.
messages: Lysosome lumen

29088:LOC110581635
gene id: 29088:LOC110581635
uniprot id: A0A2Y9H6H6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Membrane

29088:GJA9
gene id: 29088:GJA9
uniprot id: A0A2Y9GKZ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: gap junction

29088:LOC110574791
gene id: 29088:LOC110574791
uniprot id: A0A8M1MA05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with UQCC6.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

29088:LOC110587617
gene id: 29088:LOC110587617
uniprot id: A0A8M1M6U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

29088:FUZ
gene id: 29088:FUZ
uniprot id: A0A2Y9GDD9
uniprot id: A0A2Y9GHS4
uniprot id: A0A8M1M0P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fuzzy family.
messages: cytoskeleton

29088:QTRT2
gene id: 29088:QTRT2
uniprot id: A0A2Y9HFQ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.
messages: Mitochondrion outer membrane
messages: Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).

29088:POLA1
gene id: 29088:POLA1
uniprot id: A0A2Y9G3H9
uniprot id: A0A8M1M248
uniprot id: A0A8M1M5W5
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

29088:TMEM184A
gene id: 29088:TMEM184A
uniprot id: A0A2Y9GA42
names: Subcellular Location Annotation
messages: Membrane

29088:TPM3
gene id: 29088:TPM3
uniprot id: A0A2Y9GFE4
uniprot id: A0A2Y9GFE9
uniprot id: A0A2Y9GFI9
uniprot id: A0A2Y9GFJ4
uniprot id: A0A2Y9GFK8
uniprot id: A0A2Y9GFL3
uniprot id: A0A2Y9GIR6
uniprot id: A0A2Y9GIS0
uniprot id: A0A2Y9GK86
uniprot id: A0A2Y9GK91
uniprot id: A0A2Y9GK97
uniprot id: A0A8M1MD93
uniprot id: A0A8M1MGQ9
uniprot id: A0A8M1MLS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

29088:MRPS27
gene id: 29088:MRPS27
uniprot id: A0A2Y9HWL8
names: Subcellular Location Annotation
messages: Mitochondrion

29088:DEGS1
gene id: 29088:DEGS1
uniprot id: A0A2Y9G883
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:SLC35B2
gene id: 29088:SLC35B2
uniprot id: A0A2Y9HCV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

29088:TNFRSF11A
gene id: 29088:TNFRSF11A
uniprot id: A0A2Y9GXA1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:HAO1
gene id: 29088:HAO1
uniprot id: A0A2Y9GZ05
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

29088:TMEM230
gene id: 29088:TMEM230
uniprot id: A0A2Y9GZG4
uniprot id: A0A2Y9GZM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

29088:GHRL
gene id: 29088:GHRL
uniprot id: A0A2Y9HGB7
uniprot id: A0A2Y9HMN4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the motilin family.
messages: Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.
messages: O-octanoylation is essential for ghrelin activity.
messages: Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility.
messages: Secreted

29088:LOC123325493
gene id: 29088:LOC123325493
uniprot id: A0A8M1MHC2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:STXBP3
gene id: 29088:STXBP3
uniprot id: A0A2Y9H2D3
uniprot id: A0A2Y9H2F1
uniprot id: A0A2Y9H2G2
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

29088:LOC110572436
gene id: 29088:LOC110572436
uniprot id: A0A8M1MU09
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

29088:PDLIM1
gene id: 29088:PDLIM1
uniprot id: A0A2Y9I265
names: Subcellular Location Annotation
messages: Z line

29088:ZP1
gene id: 29088:ZP1
uniprot id: A0A2Y9H857
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ERF
gene id: 29088:ERF
uniprot id: A0A8M1MW58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

29088:C6H10orf53
gene id: 29088:C6H10orf53
uniprot id: A0A2Y9I2K0
names: Similarity
messages: Belongs to the UPF0728 family.

29088:ATIC
gene id: 29088:ATIC
uniprot id: A0A2Y9I4T7
uniprot id: A0A2Y9I4Z2
uniprot id: A0A2Y9I9N7
uniprot id: A0A8M1M634
uniprot id: A0A8M1M6D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PurH family.
messages: cytosol

29088:DOP1B
gene id: 29088:DOP1B
uniprot id: A0A2Y9G3W9
uniprot id: A0A2Y9G403
uniprot id: A0A8M1MXC7
names: Similarity
messages: Belongs to the dopey family.

29088:NUDT12
gene id: 29088:NUDT12
uniprot id: A0A2Y9HT33
uniprot id: A0A2Y9HT43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Cytoplasmic granule
messages: Peroxisome

29088:LOC123324583
gene id: 29088:LOC123324583
uniprot id: A0A2Y9GD22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:TRPC5
gene id: 29088:TRPC5
uniprot id: A0A8M1M403
names: Subcellular Location Annotation
messages: Membrane

29088:GPC1
gene id: 29088:GPC1
uniprot id: A0A8M1M722
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

29088:SLC16A2
gene id: 29088:SLC16A2
uniprot id: A0A2Y9GS85
names: Subcellular Location Annotation
messages: Membrane

29088:PDGFRB
gene id: 29088:PDGFRB
uniprot id: A0A2Y9HM01
uniprot id: A0A8M1MJM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Interacts with homodimeric PDGFB and PDGFD, and with heterodimers formed by PDGFA and PDGFB.
messages: Lysosome lumen
messages: Membrane
messages: Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.
messages: Vesicle

29088:LOC110587190
gene id: 29088:LOC110587190
uniprot id: A0A8M1MKS8
uniprot id: A0A8M1MP43
names: Similarity
messages: Belongs to the NAC-beta family.

29088:EVA1A
gene id: 29088:EVA1A
uniprot id: A0A2Y9HTE2
names: Similarity
messages: Belongs to the EVA1 family.

29088:FAM91A1
gene id: 29088:FAM91A1
uniprot id: A0A2Y9H3A2
names: Similarity
messages: Belongs to the FAM91 family.

29088:KDM4B
gene id: 29088:KDM4B
uniprot id: A0A8M1MHU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM3 histone demethylase family.
messages: Nucleus

29088:ADM
gene id: 29088:ADM
uniprot id: A0A2Y9GUA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adrenomedullin family.
messages: Secreted

29088:UROD
gene id: 29088:UROD
uniprot id: A0A2Y9GL83
uniprot id: A0A2Y9GQ10
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

29088:LOC110593521
gene id: 29088:LOC110593521
uniprot id: A0A2Y9I9Q7
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

29088:LOC110579414
gene id: 29088:LOC110579414
uniprot id: A0A8M1ML59
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

29088:ADGRL4
gene id: 29088:ADGRL4
uniprot id: A0A2Y9H2C8
uniprot id: A0A2Y9H7B9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:CCNB2
gene id: 29088:CCNB2
uniprot id: A0A2Y9HD52
uniprot id: A0A8M1MT73
names: Similarity
messages: Belongs to the cyclin family.

29088:TMCO4
gene id: 29088:TMCO4
uniprot id: A0A2Y9GJD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMCO4 family.
messages: Membrane

29088:LOC110575569
gene id: 29088:LOC110575569
uniprot id: A0A2Y9GQU7
names: Similarity
messages: Belongs to the MHC class II family.

29088:SCN4A
gene id: 29088:SCN4A
uniprot id: A0A2Y9G4Y5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

29088:LOC110585302
gene id: 29088:LOC110585302
uniprot id: A0A2Y9HHQ2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ALG13
gene id: 29088:ALG13
uniprot id: A0A2Y9GZ04
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

29088:ALDH16A1
gene id: 29088:ALDH16A1
uniprot id: A0A2Y9GD01
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Interacts with SPG21.

29088:LOC110575720
gene id: 29088:LOC110575720
uniprot id: A0A8M1MQ06
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

29088:LCN12
gene id: 29088:LCN12
uniprot id: A0A2Y9HAF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

29088:NAE1
gene id: 29088:NAE1
uniprot id: A0A2Y9IBX1
uniprot id: A0A2Y9IG74
uniprot id: A0A8M1M0I7
uniprot id: A0A8M1M0U1
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
messages: Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M.

29088:FAT1
gene id: 29088:FAT1
uniprot id: A0A2Y9HDF8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:CALHM3
gene id: 29088:CALHM3
uniprot id: A0A2Y9HVT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

29088:LOC110579571
gene id: 29088:LOC110579571
uniprot id: A0A8M1MNW4
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110577663
gene id: 29088:LOC110577663
uniprot id: A0A8M1M8X6
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

29088:ACSL5
gene id: 29088:ACSL5
uniprot id: A0A2Y9HW61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion outer membrane

29088:GUF1
gene id: 29088:GUF1
uniprot id: A0A2Y9HZV5
uniprot id: A0A2Y9I068
uniprot id: A0A2Y9I0C3
uniprot id: A0A2Y9I4V0
uniprot id: A0A2Y9I6Q9
uniprot id: A0A8M1M464
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

29088:PPIP5K1
gene id: 29088:PPIP5K1
uniprot id: A0A2Y9HI25
uniprot id: A0A8M1MKF5
uniprot id: A0A8M1MKF6
uniprot id: A0A8M1MKG0
uniprot id: A0A8M1MKG1
uniprot id: A0A8M1MMG7
uniprot id: A0A8M1MMH2
uniprot id: A0A8M1MNS2
uniprot id: A0A8M1MNS7
uniprot id: A0A8M1MUJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

29088:CRYAB
gene id: 29088:CRYAB
uniprot id: A0A2Y9HJY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Contributes to the transparency and refractive index of the lens. Acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
messages: Cytoplasm
messages: Heteromer composed of three CRYAA and one CRYAB subunits. Inter-subunit bridging via zinc ions enhances stability, which is crucial as there is no protein turn over in the lens. Can also form homodimers and homotetramers (dimers of dimers) which serve as the building blocks of homooligomers (By similarity). Within homooligomers, the zinc-binding motif is created from residues of 3 different molecules. His-100 and Glu-102 from one molecule are ligands of the zinc ion, and His-107 and His-154 residues from additional molecules complete the site with tetrahedral coordination geometry (By similarity). Part of a complex required for lens intermediate filament formation composed of BFSP1, BFSP2 and CRYAA.
messages: May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
messages: Nucleus

29088:CELF1
gene id: 29088:CELF1
uniprot id: A0A8M1MMY0
uniprot id: A0A8M1MMY2
uniprot id: A0A8M1MMY6
uniprot id: A0A8M1MMY7
uniprot id: A0A8M1MPW3
uniprot id: A0A8M1MPW7
uniprot id: A0A8M1MR94
uniprot id: A0A8M1MR97
uniprot id: A0A8M1MX21
uniprot id: A0A8M1MX24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

29088:RC3H1
gene id: 29088:RC3H1
uniprot id: A0A2Y9GKI4
uniprot id: A0A8M1MH09
names: Subcellular Location Annotation
messages: P-body

29088:PSMD12
gene id: 29088:PSMD12
uniprot id: A0A2Y9G4Z6
uniprot id: A0A8M1MVQ0
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

29088:LOC110581671
gene id: 29088:LOC110581671
uniprot id: A0A2Y9H6G6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110589766
gene id: 29088:LOC110589766
uniprot id: A0A2Y9HWE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Nucleus

29088:CLCF1
gene id: 29088:CLCF1
uniprot id: A0A2Y9GSH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

29088:LOC110570803
gene id: 29088:LOC110570803
uniprot id: A0A2Y9G672
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

29088:PAGE4
gene id: 29088:PAGE4
uniprot id: A0A2Y9G7L4
names: Similarity
messages: Belongs to the GAGE family.

29088:LOC110589350
gene id: 29088:LOC110589350
uniprot id: A0A2Y9HVJ6
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:GATAD1
gene id: 29088:GATAD1
uniprot id: A0A2Y9H630
names: Subcellular Location Annotation
messages: Nucleus

29088:MTM1
gene id: 29088:MTM1
uniprot id: A0A2Y9GIT4
uniprot id: A0A2Y9GP22
uniprot id: A0A8M1M4U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

29088:BEX3
gene id: 29088:BEX3
uniprot id: A0A2Y9HAV5
uniprot id: A0A2Y9HC90
names: Similarity
messages: Belongs to the BEX family.

29088:CACNA1I
gene id: 29088:CACNA1I
uniprot id: A0A8M1MLK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.

29088:LOC110578548
gene id: 29088:LOC110578548
uniprot id: A0A2Y9GWN8
uniprot id: A0A2Y9GWZ1
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

29088:KRT20
gene id: 29088:KRT20
uniprot id: A0A2Y9IFH7
names: Similarity
messages: Belongs to the intermediate filament family.

29088:RAMP3
gene id: 29088:RAMP3
uniprot id: A0A8M1MSG7
names: Similarity
messages: Belongs to the RAMP family.

29088:PPIL2
gene id: 29088:PPIL2
uniprot id: A0A2Y9GWD3
uniprot id: A0A8M1MYW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
messages: Nucleus

29088:FXR1
gene id: 29088:FXR1
uniprot id: A0A2Y9HG22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cytoplasmic ribonucleoprotein granule
messages: Nucleus envelope
messages: Postsynapse
messages: Synapse
messages: dendritic spine

29088:GABRQ
gene id: 29088:GABRQ
uniprot id: A0A2Y9GPM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:SLC1A6
gene id: 29088:SLC1A6
uniprot id: A0A2Y9GID4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

29088:CYGB
gene id: 29088:CYGB
uniprot id: A0A2Y9GCD0
names: Similarity
messages: Belongs to the globin family.

29088:GNG3
gene id: 29088:GNG3
uniprot id: A0A2Y9GTN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

29088:SLIT1
gene id: 29088:SLIT1
uniprot id: A0A2Y9HVA0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:CPNE6
gene id: 29088:CPNE6
uniprot id: A0A2Y9HHE5
names: Similarity
messages: Belongs to the copine family.

29088:FTSJ1
gene id: 29088:FTSJ1
uniprot id: A0A2Y9G765
uniprot id: A0A2Y9G984
uniprot id: A0A2Y9GAD0
uniprot id: A0A2Y9GAE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

29088:DDOST
gene id: 29088:DDOST
uniprot id: A0A2Y9GKN7
uniprot id: A0A2Y9GKY5
uniprot id: A0A2Y9GR22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

29088:BRPF1
gene id: 29088:BRPF1
uniprot id: A0A2Y9HFS4
uniprot id: A0A2Y9HFY5
uniprot id: A0A2Y9HG68
uniprot id: A0A2Y9HG73
uniprot id: A0A2Y9HM47
uniprot id: A0A2Y9HM96
uniprot id: A0A8M1MH79
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110593289
gene id: 29088:LOC110593289
uniprot id: A0A2Y9ICY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

29088:MNX1
gene id: 29088:MNX1
uniprot id: A0A8M1MQ43
names: Subcellular Location Annotation
messages: Nucleus

29088:MRPL32
gene id: 29088:MRPL32
uniprot id: A0A2Y9I6P2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

29088:LOC110580995
gene id: 29088:LOC110580995
uniprot id: A0A8M1MCT7
names: Subcellular Location Annotation
messages: Nucleus

29088:IRF4
gene id: 29088:IRF4
uniprot id: A0A2Y9HSG0
uniprot id: A0A2Y9HTP8
names: Subcellular Location Annotation
messages: Nucleus

29088:ZFX
gene id: 29088:ZFX
uniprot id: A0A2Y9IIW8
names: Subcellular Location Annotation
messages: Nucleus

29088:ZDHHC8
gene id: 29088:ZDHHC8
uniprot id: A0A2Y9H9V7
uniprot id: A0A2Y9HB65
uniprot id: A0A8M1MWR0
uniprot id: A0A8M1MYZ0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

29088:NDE1
gene id: 29088:NDE1
uniprot id: A0A2Y9HQS8
uniprot id: A0A2Y9HX88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: kinetochore
messages: spindle

29088:DMC1
gene id: 29088:DMC1
uniprot id: A0A2Y9GZY1
uniprot id: A0A2Y9H1P8
names: Similarity
messages: Belongs to the RecA family.
messages: Belongs to the RecA family. DMC1 subfamily.

29088:LOC110578126
gene id: 29088:LOC110578126
uniprot id: A0A2Y9GVU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:RFC4
gene id: 29088:RFC4
uniprot id: A0A2Y9HFX6
names: Similarity
messages: Belongs to the activator 1 small subunits family.

29088:RPS18
gene id: 29088:RPS18
uniprot id: A0A2Y9GSF5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Component of the small ribosomal subunit.

29088:DCLK1
gene id: 29088:DCLK1
uniprot id: A0A2Y9G4J3
uniprot id: A0A2Y9G509
uniprot id: A0A2Y9G868
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

29088:STXBP5L
gene id: 29088:STXBP5L
uniprot id: A0A2Y9HFS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

29088:A1CF
gene id: 29088:A1CF
uniprot id: A0A2Y9HR26
names: Subcellular Location Annotation
messages: Cytoplasm

29088:CDX2
gene id: 29088:CDX2
uniprot id: A0A2Y9G4I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

29088:MRPL40
gene id: 29088:MRPL40
uniprot id: A0A2Y9H4H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL40 family.
messages: Mitochondrion

29088:CIT
gene id: 29088:CIT
uniprot id: A0A2Y9I612
uniprot id: A0A2Y9IAK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Plays a role in cytokinesis. Displays serine/threonine protein kinase activity.

29088:CBFA2T2
gene id: 29088:CBFA2T2
uniprot id: A0A2Y9GZL2
uniprot id: A0A8M1ML58
names: Similarity
messages: Belongs to the CBFA2T family.

29088:UCMA
gene id: 29088:UCMA
uniprot id: A0A2Y9HL46
uniprot id: A0A2Y9HLB7
uniprot id: A0A2Y9HRS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UCMA family.
messages: May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.
messages: extracellular matrix

29088:LOC110576095
gene id: 29088:LOC110576095
uniprot id: A0A2Y9GNM7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SERINC2
gene id: 29088:SERINC2
uniprot id: A0A2Y9GJP9
uniprot id: A0A8M1MA31
uniprot id: A0A8M1MFZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

29088:MFSD14A
gene id: 29088:MFSD14A
uniprot id: A0A2Y9H222
uniprot id: A0A2Y9H245
uniprot id: A0A2Y9H259
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

29088:NIM1K
gene id: 29088:NIM1K
uniprot id: A0A2Y9HSA4
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:U2AF2
gene id: 29088:U2AF2
uniprot id: A0A2Y9GFZ2
uniprot id: A0A2Y9GG09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Necessary for the splicing of pre-mRNA.
messages: Nucleus

29088:LPGAT1
gene id: 29088:LPGAT1
uniprot id: A0A8M1MI50
uniprot id: A0A8M1MNC6
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

29088:ADGRB3
gene id: 29088:ADGRB3
uniprot id: A0A2Y9H7J5
names: Subcellular Location Annotation
messages: Membrane

29088:PURB
gene id: 29088:PURB
uniprot id: A0A2Y9IDA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

29088:SLC25A6
gene id: 29088:SLC25A6
uniprot id: A0A8M1M8W0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

29088:ANK1
gene id: 29088:ANK1
uniprot id: A0A8M1M6X9
uniprot id: A0A8M1MCH3
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

29088:LOC110576271
gene id: 29088:LOC110576271
uniprot id: A0A2Y9GPA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aldolase class II family. Adducin subfamily.
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.
messages: Cytoplasm
messages: Homotetramer. Interacts with APAF1. May interact with CASP1.

29088:LOC123323387
gene id: 29088:LOC123323387
uniprot id: A0A8M1M539
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:LOC123326511
gene id: 29088:LOC123326511
uniprot id: A0A8M1MS86
uniprot id: A0A8M1MVG1
names: Similarity
messages: Belongs to the NAC-beta family.

29088:BEST1
gene id: 29088:BEST1
uniprot id: A0A2Y9GTL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.
messages: Cell membrane
messages: Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
messages: Membrane

29088:LOC110579510
gene id: 29088:LOC110579510
uniprot id: A0A8M1MVW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

29088:NSMCE1
gene id: 29088:NSMCE1
uniprot id: A0A2Y9HX60
uniprot id: A0A8M1MET0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE1 family.
messages: Component of the Smc5-Smc6 complex.
messages: Nucleus
messages: RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate. Involved in maintenance of genome integrity, DNA damage response and DNA repair.
messages: telomere

29088:DUSP4
gene id: 29088:DUSP4
uniprot id: A0A2Y9HDG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

29088:TENT5A
gene id: 29088:TENT5A
uniprot id: A0A2Y9HGZ0
names: Similarity
messages: Belongs to the TENT family.

29088:NCAPH
gene id: 29088:NCAPH
uniprot id: A0A2Y9HUZ6
uniprot id: A0A8M1MLC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.

29088:SH3YL1
gene id: 29088:SH3YL1
uniprot id: A0A2Y9HTC4
uniprot id: A0A2Y9HUR7
names: Similarity
names: Subunit
messages: Belongs to the SH3YL1 family.
messages: Interacts with SH3D19.

29088:GCHFR
gene id: 29088:GCHFR
uniprot id: A0A2Y9HHZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GFRP family.
messages: Membrane
messages: Nucleus membrane
messages: cytosol

29088:KLHL3
gene id: 29088:KLHL3
uniprot id: A0A2Y9I5S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KLHL3 family.
messages: cytoskeleton
messages: cytosol

29088:FAM174C
gene id: 29088:FAM174C
uniprot id: A0A2Y9IAN6
uniprot id: A0A2Y9IBE2
uniprot id: A0A2Y9IHZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

29088:OLFM1
gene id: 29088:OLFM1
uniprot id: A0A2Y9H5E3
uniprot id: A0A8M1MR19
uniprot id: A0A8M1MR29
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

29088:GJB4
gene id: 29088:GJB4
uniprot id: A0A2Y9GPU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

29088:LOC110573126
gene id: 29088:LOC110573126
uniprot id: A0A8M1M4D0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:FGF1
gene id: 29088:FGF1
uniprot id: A0A2Y9I103
uniprot id: A0A2Y9I5N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

29088:LOC110585276
gene id: 29088:LOC110585276
uniprot id: A0A8M1MMY8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

29088:CPNE2
gene id: 29088:CPNE2
uniprot id: A0A2Y9IBW2
uniprot id: A0A8M1MY05
uniprot id: A0A8M1MZF6
names: Similarity
messages: Belongs to the copine family.

29088:EPN2
gene id: 29088:EPN2
uniprot id: A0A2Y9HFA5
uniprot id: A0A2Y9HFP9
uniprot id: A0A2Y9HLP6
uniprot id: A0A2Y9HLP9
uniprot id: A0A8M1MZ78
names: Similarity
messages: Belongs to the epsin family.

29088:LOC110593467
gene id: 29088:LOC110593467
uniprot id: A0A8M1MP99
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the splicing factor SR family.
messages: Found in mRNA splicing-dependent exon junction complexes (EJC). Found in a post-splicing complex with NXF1, RBM8A, UPF1, UPF2, UPF3A, UPF3B and RNPS1. Component of the heterotrimeric ASAP (apoptosis- and splicing-associated protein) and PSAP complexes consisting of RNPS1, SAP18 and either ACIN1 or PNN, respectively; the ASAP and PSAP complexes probably are formed mutually exclusive. Component of the active spliceosome. Associates with polysomes. Interacts with the cleaved p110 isoform of CDC2L1, CSNK2A1, PNN, SART3, SRP54, SRRM1 and TRA2B/SFRS10.
messages: Nucleus speckle

29088:KCMF1
gene id: 29088:KCMF1
uniprot id: A0A2Y9HN50
names: Function
names: Similarity
messages: Belongs to the KCMF1 family.
messages: Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination.

29088:SHMT2
gene id: 29088:SHMT2
uniprot id: A0A2Y9GYS7
uniprot id: A0A8M1MA28
uniprot id: A0A8M1MCF0
uniprot id: A0A8M1MII9
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

29088:SHOX2
gene id: 29088:SHOX2
uniprot id: A0A2Y9I2X6
uniprot id: A0A8M1MB40
names: Subcellular Location Annotation
messages: Nucleus

29088:ACOX2
gene id: 29088:ACOX2
uniprot id: A0A2Y9HGB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

29088:STK10
gene id: 29088:STK10
uniprot id: A0A2Y9HQI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Cell membrane

29088:C4H1orf174
gene id: 29088:C4H1orf174
uniprot id: A0A2Y9GIR0
uniprot id: A0A2Y9GMB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0688 family.
messages: Nucleus

29088:HS6ST2
gene id: 29088:HS6ST2
uniprot id: A0A8M1M1V1
uniprot id: A0A8M1M5L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

29088:OPA3
gene id: 29088:OPA3
uniprot id: A0A2Y9GFN8
names: Function
names: Similarity
messages: Belongs to the OPA3 family.
messages: May play some role in mitochondrial processes.

29088:RTN1
gene id: 29088:RTN1
uniprot id: A0A2Y9HZP8
uniprot id: A0A2Y9I638
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:LOC110594269
gene id: 29088:LOC110594269
uniprot id: A0A2Y9ICQ7
uniprot id: A0A8M1M0J8
uniprot id: A0A8M1M0V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL2BP family.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Nucleus
messages: Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.
messages: centrosome
messages: cilium basal body

29088:DERL2
gene id: 29088:DERL2
uniprot id: A0A2Y9HFA6
uniprot id: A0A8M1MUD6
uniprot id: A0A8M1MW69
uniprot id: A0A8M1MZ39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:TMEM218
gene id: 29088:TMEM218
uniprot id: A0A2Y9HJI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM218 family.
messages: May be involved in ciliary biogenesis or function.
messages: Membrane
messages: cilium

29088:PTGES
gene id: 29088:PTGES
uniprot id: A0A2Y9H6S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

29088:MACIR
gene id: 29088:MACIR
uniprot id: A0A2Y9HSR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UNC119-binding protein family.
messages: Cytoplasm
messages: cilium

29088:LOC110590450
gene id: 29088:LOC110590450
uniprot id: A0A8M1MNQ5
names: Similarity
messages: Belongs to the PRORSD1 family.

29088:LOC110580473
gene id: 29088:LOC110580473
uniprot id: A0A2Y9H2P1
names: Similarity
messages: Belongs to the peptidase A1 family.

29088:LOC123323407
gene id: 29088:LOC123323407
uniprot id: A0A2Y9HDM8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:CTNNA1
gene id: 29088:CTNNA1
uniprot id: A0A2Y9I0R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction

29088:GMDS
gene id: 29088:GMDS
uniprot id: A0A8M1MHB3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

29088:DCLRE1B
gene id: 29088:DCLRE1B
uniprot id: A0A2Y9H2X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

29088:ABLIM2
gene id: 29088:ABLIM2
uniprot id: A0A8M1MCB8
names: Subcellular Location Annotation
messages: Cytoplasm

29088:EXOC3L4
gene id: 29088:EXOC3L4
uniprot id: A0A2Y9GBA1
names: Similarity
messages: Belongs to the SEC6 family.

29088:MDGA1
gene id: 29088:MDGA1
uniprot id: A0A2Y9GR16
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:FZD7
gene id: 29088:FZD7
uniprot id: A0A2Y9IAQ7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:CHMP1A
gene id: 29088:CHMP1A
uniprot id: A0A2Y9I2G0
names: Similarity
messages: Belongs to the SNF7 family.

29088:RPL32
gene id: 29088:RPL32
uniprot id: A0A2Y9HGL0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

29088:RELL1
gene id: 29088:RELL1
uniprot id: A0A2Y9HZW3
names: Similarity
messages: Belongs to the RELT family.

29088:DBT
gene id: 29088:DBT
uniprot id: A0A2Y9H277
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

29088:LOC110577788
gene id: 29088:LOC110577788
uniprot id: A0A2Y9GUC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

29088:HIP1R
gene id: 29088:HIP1R
uniprot id: A0A2Y9HRC0
uniprot id: A0A2Y9HXS8
names: Similarity
messages: Belongs to the SLA2 family.

29088:LEAP2
gene id: 29088:LEAP2
uniprot id: A0A2Y9I1C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEAP2 family.
messages: Has an antimicrobial activity.
messages: Secreted

29088:SLC9A1
gene id: 29088:SLC9A1
uniprot id: A0A2Y9GKX8
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

29088:UBE2H
gene id: 29088:UBE2H
uniprot id: A0A2Y9HTM4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

29088:MED9
gene id: 29088:MED9
uniprot id: A0A2Y9HLF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 9 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

29088:CNOT7
gene id: 29088:CNOT7
uniprot id: A0A2Y9HE19
uniprot id: A0A8M1M1W1
uniprot id: A0A8M1M438
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

29088:MYOG
gene id: 29088:MYOG
uniprot id: A0A2Y9GWP2
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110571781
gene id: 29088:LOC110571781
uniprot id: A0A2Y9G9C8
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:AK8
gene id: 29088:AK8
uniprot id: A0A2Y9H6C9
uniprot id: A0A8M1MTP9
names: Similarity
messages: Belongs to the adenylate kinase family.

29088:PIPOX
gene id: 29088:PIPOX
uniprot id: A0A2Y9IEC9
names: Similarity
messages: Belongs to the MSOX/MTOX family.

29088:RCAN3
gene id: 29088:RCAN3
uniprot id: A0A2Y9GJG8
names: Similarity
messages: Belongs to the RCAN family.

29088:EGF
gene id: 29088:EGF
uniprot id: A0A2Y9GLR0
uniprot id: A0A2Y9GLW0
uniprot id: A0A2Y9GM28
names: Caution
names: Function
names: Subunit
messages: EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
messages: Interacts with EGFR and promotes EGFR dimerization.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:OCEL1
gene id: 29088:OCEL1
uniprot id: A0A2Y9GNB3
names: Similarity
messages: Belongs to the ELL/occludin family.

29088:LOC110574515
gene id: 29088:LOC110574515
uniprot id: A0A2Y9GI89
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ITGA8
gene id: 29088:ITGA8
uniprot id: A0A2Y9HKW3
uniprot id: A0A2Y9HRK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

29088:LOC123323399
gene id: 29088:LOC123323399
uniprot id: A0A8M1M9H5
names: Similarity
messages: Belongs to the Gfa family.

29088:LOC110572573
gene id: 29088:LOC110572573
uniprot id: A0A8M1MUL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

29088:CNOT6
gene id: 29088:CNOT6
uniprot id: A0A8M1MJ68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

29088:LSM3
gene id: 29088:LSM3
uniprot id: A0A2Y9HN52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

29088:ERI1
gene id: 29088:ERI1
uniprot id: A0A2Y9HDS9
names: Subcellular Location Annotation
messages: Cytoplasm

29088:JAK2
gene id: 29088:JAK2
uniprot id: A0A2Y9HEH0
uniprot id: A0A2Y9HKP7
uniprot id: A0A2Y9HKV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system
messages: Nucleus

29088:TNFAIP6
gene id: 29088:TNFAIP6
uniprot id: A0A2Y9I938
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ZFYVE28
gene id: 29088:ZFYVE28
uniprot id: A0A8M1M5A7
names: Similarity
messages: Belongs to the lst-2 family.

29088:ZNF18
gene id: 29088:ZNF18
uniprot id: A0A2Y9HLF5
names: Subcellular Location Annotation
messages: Nucleus

29088:MED1
gene id: 29088:MED1
uniprot id: A0A2Y9I7E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

29088:FXYD3
gene id: 29088:FXYD3
uniprot id: A0A2Y9I4U0
names: Similarity
messages: Belongs to the FXYD family.

29088:LOC110586072
gene id: 29088:LOC110586072
uniprot id: A0A2Y9HJR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:HTR1F
gene id: 29088:HTR1F
uniprot id: A0A2Y9H0N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
messages: Membrane

29088:AGPAT1
gene id: 29088:AGPAT1
uniprot id: A0A8M1MI44
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

29088:SH3GLB1
gene id: 29088:SH3GLB1
uniprot id: A0A2Y9H9G4
uniprot id: A0A8M1M893
uniprot id: A0A8M1MBT2
uniprot id: A0A8M1MGC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Golgi apparatus membrane
messages: Midbody
messages: Mitochondrion outer membrane
messages: autophagosome membrane

29088:SSTR4
gene id: 29088:SSTR4
uniprot id: A0A2Y9HXL0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:RPS28
gene id: 29088:RPS28
uniprot id: A0A2Y9IH02
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

29088:LOC110580791
gene id: 29088:LOC110580791
uniprot id: A0A8M1MBH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

29088:STX2
gene id: 29088:STX2
uniprot id: A0A8M1MUQ2
uniprot id: A0A8M1MYT5
names: Similarity
messages: Belongs to the syntaxin family.

29088:LTBP4
gene id: 29088:LTBP4
uniprot id: A0A8M1M2Q9
uniprot id: A0A8M1M7V9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:TMEM43
gene id: 29088:TMEM43
uniprot id: A0A2Y9HMP1
uniprot id: A0A2Y9HMW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM43 family.
messages: Membrane

29088:LOC110593062
gene id: 29088:LOC110593062
uniprot id: A0A2Y9I7L5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:GPCPD1
gene id: 29088:GPCPD1
uniprot id: A0A2Y9GZT3
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

29088:LOC110580058
gene id: 29088:LOC110580058
uniprot id: A0A8M1MYA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

29088:FAM83B
gene id: 29088:FAM83B
uniprot id: A0A2Y9HEE2
names: Similarity
messages: Belongs to the FAM83 family.

29088:LOC110584749
gene id: 29088:LOC110584749
uniprot id: A0A8M1M1Q6
names: Similarity
messages: Belongs to the costars family.

29088:STAM
gene id: 29088:STAM
uniprot id: A0A2Y9HRI1
uniprot id: A0A8M1MED9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane
messages: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.

29088:CRISP1
gene id: 29088:CRISP1
uniprot id: A0A2Y9HDJ8
names: Caution
names: Similarity
messages: Belongs to the CRISP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:HSDL1
gene id: 29088:HSDL1
uniprot id: A0A2Y9I358
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29088:VEGFD
gene id: 29088:VEGFD
uniprot id: A0A8M1M930
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

29088:NAPG
gene id: 29088:NAPG
uniprot id: A0A2Y9H5I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

29088:CACNA2D1
gene id: 29088:CACNA2D1
uniprot id: A0A2Y9H1L7
uniprot id: A0A2Y9H1N9
uniprot id: A0A2Y9H1P3
uniprot id: A0A2Y9H1Q8
uniprot id: A0A2Y9H6I9
uniprot id: A0A2Y9H6J4
uniprot id: A0A2Y9H862
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

29088:TM6SF2
gene id: 29088:TM6SF2
uniprot id: A0A2Y9GN33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TM6SF family.
messages: Membrane

29088:TEC
gene id: 29088:TEC
uniprot id: A0A2Y9I079
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

29088:TMC8
gene id: 29088:TMC8
uniprot id: A0A8M1MUR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

29088:LOC110575705
gene id: 29088:LOC110575705
uniprot id: A0A2Y9GMM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

29088:WNT1
gene id: 29088:WNT1
uniprot id: A0A2Y9IGP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

29088:ZNF711
gene id: 29088:ZNF711
uniprot id: A0A2Y9GIL4
uniprot id: A0A8M1M3E4
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC123324301
gene id: 29088:LOC123324301
uniprot id: A0A8M1M637
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase inhibitor family.
messages: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase.
messages: Forms an alpha-helical dimer with monomers associated via an antiparallel alpha-helical coiled coil, leaving each N-terminal inhibitory region accessible for interaction with an F1 catalytic domain. The inhibitory N-terminal region binds the alpha(ADP-bound)-beta(ADP-bound) (ATP5F1A-ATP5F1B) interface of F1-ATPase, and also contact the central gamma subunit (ATP5F1C). This dimeric state is favored by pH values below 7.0, and at higher values the dimers associate to form inactive homotetramer, where the inhibitory region is occluded, masking its inhibitory activity.
messages: Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0.
messages: Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
messages: Mitochondrion

29088:LOC110573238
gene id: 29088:LOC110573238
uniprot id: A0A2Y9GE93
uniprot id: A0A2Y9GED5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 2H phosphoesterase superfamily. CNPase family.
messages: Exists as monomers and homodimers.
messages: May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.
messages: Melanosome
messages: Membrane

29088:TMSB4X
gene id: 29088:TMSB4X
uniprot id: A0A2Y9GFX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

29088:DDX31
gene id: 29088:DDX31
uniprot id: A0A2Y9HD79
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

29088:C14H18orf25
gene id: 29088:C14H18orf25
uniprot id: A0A2Y9GVY0
uniprot id: A0A2Y9GXJ3
names: Subcellular Location Annotation
messages: Nucleus

29088:SEMA4C
gene id: 29088:SEMA4C
uniprot id: A0A2Y9I3N5
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:PSME3
gene id: 29088:PSME3
uniprot id: A0A2Y9GHJ8
uniprot id: A0A8M1MXQ2
uniprot id: A0A8M1MZA5
names: Similarity
messages: Belongs to the PA28 family.

29088:LDLRAD1
gene id: 29088:LDLRAD1
uniprot id: A0A2Y9GKC4
uniprot id: A0A2Y9GKI7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110593430
gene id: 29088:LOC110593430
uniprot id: A0A2Y9I8T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

29088:LOC110587126
gene id: 29088:LOC110587126
uniprot id: A0A2Y9HUB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

29088:NDUFA1
gene id: 29088:NDUFA1
uniprot id: A0A2Y9GRM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:TGFA
gene id: 29088:TGFA
uniprot id: A0A2Y9HT73
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:SNTG1
gene id: 29088:SNTG1
uniprot id: A0A2Y9H257
uniprot id: A0A2Y9H4A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

29088:LOC110589596
gene id: 29088:LOC110589596
uniprot id: A0A2Y9HW60
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:TMEM200B
gene id: 29088:TMEM200B
uniprot id: A0A2Y9GL63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

29088:LOC110569926
gene id: 29088:LOC110569926
uniprot id: A0A8M1MRU1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

29088:BCKDHA
gene id: 29088:BCKDHA
uniprot id: A0A2Y9HYB3
uniprot id: A0A8M1MW11
uniprot id: A0A8M1MW17
uniprot id: A0A8M1MXC9
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: Together with BCKDHB forms the heterotetrameric E1 subunit of the mitochondrial branched-chain alpha-ketoacid dehydrogenase (BCKD) complex. The BCKD complex catalyzes the multi-step oxidative decarboxylation of alpha-ketoacids derived from the branched-chain amino-acids valine, leucine and isoleucine producing CO2 and acyl-CoA which is subsequently utilized to produce energy. The E1 subunit catalyzes the first step with the decarboxylation of the alpha-ketoacid forming an enzyme-product intermediate. A reductive acylation mediated by the lipoylamide cofactor of E2 extracts the acyl group from the E1 active site for the next step of the reaction.

29088:LOC110572549
gene id: 29088:LOC110572549
uniprot id: A0A2Y9GBZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:PLAT
gene id: 29088:PLAT
uniprot id: A0A8M1M374
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:LOC110593121
gene id: 29088:LOC110593121
uniprot id: A0A2Y9I835
names: Subcellular Location Annotation
messages: Nucleus

29088:HLX
gene id: 29088:HLX
uniprot id: A0A2Y9HR71
names: Subcellular Location Annotation
messages: Nucleus

29088:CSMD3
gene id: 29088:CSMD3
uniprot id: A0A2Y9GXU1
uniprot id: A0A2Y9GXV9
uniprot id: A0A8M1MH07
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110571301
gene id: 29088:LOC110571301
uniprot id: A0A8M1M498
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion membrane

29088:LOC110582119
gene id: 29088:LOC110582119
uniprot id: A0A8M1M2G9
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

29088:MEN1
gene id: 29088:MEN1
uniprot id: A0A2Y9GPW1
uniprot id: A0A2Y9GVC2
names: Subcellular Location Annotation
messages: Nucleus

29088:DCAF11
gene id: 29088:DCAF11
uniprot id: A0A2Y9HPD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat LEC14B family.
messages: Interacts with DDB1 and CUL4A.
messages: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

29088:PCID2
gene id: 29088:PCID2
uniprot id: A0A2Y9HPW5
uniprot id: A0A2Y9HQJ9
uniprot id: A0A8M1M6D9
uniprot id: A0A8M1M6P3
uniprot id: A0A8M1M8U0
names: Similarity
messages: Belongs to the CSN12 family.

29088:DHCR7
gene id: 29088:DHCR7
uniprot id: A0A2Y9GNJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

29088:USP45
gene id: 29088:USP45
uniprot id: A0A2Y9HBM4
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

29088:DHRS7
gene id: 29088:DHRS7
uniprot id: A0A2Y9HZC5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29088:ATP9B
gene id: 29088:ATP9B
uniprot id: A0A2Y9GRC4
uniprot id: A0A8M1MTH3
uniprot id: A0A8M1MTH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

29088:GNB4
gene id: 29088:GNB4
uniprot id: A0A2Y9H8U1
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

29088:S100A12
gene id: 29088:S100A12
uniprot id: A0A2Y9GF61
names: Similarity
messages: Belongs to the S-100 family.

29088:THTPA
gene id: 29088:THTPA
uniprot id: A0A2Y9HHE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Hydrolase highly specific for thiamine triphosphate (ThTP).
messages: Monomer.

29088:GPX6
gene id: 29088:GPX6
uniprot id: A0A2Y9HM57
names: Similarity
messages: Belongs to the glutathione peroxidase family.

29088:KIF17
gene id: 29088:KIF17
uniprot id: A0A2Y9GLK3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:SLC10A1
gene id: 29088:SLC10A1
uniprot id: A0A2Y9G988
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

29088:HHIPL2
gene id: 29088:HHIPL2
uniprot id: A0A2Y9HW32
names: Similarity
messages: Belongs to the HHIP family.

29088:LOC110577715
gene id: 29088:LOC110577715
uniprot id: A0A8M1M241
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

29088:KIF16B
gene id: 29088:KIF16B
uniprot id: A0A2Y9HXE6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:SLC16A11
gene id: 29088:SLC16A11
uniprot id: A0A2Y9HF13
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110572103
gene id: 29088:LOC110572103
uniprot id: A0A8M1MBZ1
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

29088:LOC110580104
gene id: 29088:LOC110580104
uniprot id: A0A8M1MQG0
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

29088:ACKR4
gene id: 29088:ACKR4
uniprot id: A0A2Y9G608
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:MAP3K6
gene id: 29088:MAP3K6
uniprot id: A0A8M1MB49
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

29088:DAPK3
gene id: 29088:DAPK3
uniprot id: A0A2Y9IHP7
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:RAB43
gene id: 29088:RAB43
uniprot id: A0A2Y9HGM6
uniprot id: A0A2Y9HGU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane

29088:EIF4G2
gene id: 29088:EIF4G2
uniprot id: A0A8M1MR85
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

29088:MAU2
gene id: 29088:MAU2
uniprot id: A0A2Y9GLS7
uniprot id: A0A2Y9GNL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC4/mau-2 family.
messages: nucleoplasm

29088:ARPC2
gene id: 29088:ARPC2
uniprot id: A0A2Y9IAC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Cell projection
messages: Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Interacts with SHANK3; the interaction probably mediates the association of SHANK3 with the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton
messages: synaptosome

29088:LOC110576109
gene id: 29088:LOC110576109
uniprot id: A0A2Y9GSQ3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110590018
gene id: 29088:LOC110590018
uniprot id: A0A8M1MLR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

29088:RIOK3
gene id: 29088:RIOK3
uniprot id: A0A2Y9GR09
uniprot id: A0A2Y9GWS0
uniprot id: A0A8M1MTM3
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
messages: Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses.

29088:SNRPE
gene id: 29088:SNRPE
uniprot id: A0A2Y9GY41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

29088:SIRT5
gene id: 29088:SIRT5
uniprot id: A0A2Y9HMU7
uniprot id: A0A2Y9HU99
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: In contrast to class I sirtuins, class III sirtuins have only weak deacetylase activity. Difference in substrate specificity is probably due to a larger hydrophobic pocket with 2 residues (Tyr-102 and Arg-105) that bind to malonylated and succinylated substrates and define the specificity.
messages: In contrast to class I sirtuins, class III sirtuins have only weak deacetylase activity. Difference in substrate specificity is probably due to a larger hydrophobic pocket with 2 residues (Tyr-83 and Arg-86) that bind to malonylated and succinylated substrates and define the specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Monomer. Homodimer. Interacts with CPS1.
messages: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinylation and activation of HMGCS2. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro such as Uox.
messages: Nucleus
messages: cytosol

29088:PPM1A
gene id: 29088:PPM1A
uniprot id: A0A2Y9I4G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

29088:DYNLT1
gene id: 29088:DYNLT1
uniprot id: A0A2Y9HBH5
uniprot id: A0A2Y9HBM1
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

29088:HHATL
gene id: 29088:HHATL
uniprot id: A0A2Y9G6K4
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110573356
gene id: 29088:LOC110573356
uniprot id: A0A2Y9GEQ0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SULF1
gene id: 29088:SULF1
uniprot id: A0A2Y9H200
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack

29088:LOC110571488
gene id: 29088:LOC110571488
uniprot id: A0A8M1MIZ2
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

29088:MAN2A1
gene id: 29088:MAN2A1
uniprot id: A0A2Y9I4J9
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

29088:SPTA1
gene id: 29088:SPTA1
uniprot id: A0A2Y9GEW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spectrin family.
messages: cell cortex
messages: cytoskeleton

29088:NR5A1
gene id: 29088:NR5A1
uniprot id: A0A2Y9HCD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

29088:RAMAC
gene id: 29088:RAMAC
uniprot id: A0A2Y9GBL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAM family.
messages: Nucleus

29088:ADAMTS12
gene id: 29088:ADAMTS12
uniprot id: A0A2Y9HIU3
uniprot id: A0A2Y9HIU9
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:LOC110590165
gene id: 29088:LOC110590165
uniprot id: A0A8M1MZH8
names: Similarity
messages: Belongs to the CSN9 family.

29088:NIPSNAP2
gene id: 29088:NIPSNAP2
uniprot id: A0A2Y9HWU1
names: Similarity
messages: Belongs to the NipSnap family.

29088:LOC110569677
gene id: 29088:LOC110569677
uniprot id: A0A8M1MVM3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

29088:TNNI3
gene id: 29088:TNNI3
uniprot id: A0A2Y9GFZ8
uniprot id: A0A2Y9GKU1
names: Function
names: Similarity
messages: Belongs to the troponin I family.
messages: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

29088:SLC18A3
gene id: 29088:SLC18A3
uniprot id: A0A2Y9HW89
names: Subcellular Location Annotation
messages: Membrane

29088:LOC123326233
gene id: 29088:LOC123326233
uniprot id: A0A8M1MSP2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SGTB
gene id: 29088:SGTB
uniprot id: A0A2Y9I148
names: Similarity
messages: Belongs to the SGT family.

29088:SIGMAR1
gene id: 29088:SIGMAR1
uniprot id: A0A2Y9H604
uniprot id: A0A2Y9HBD7
uniprot id: A0A2Y9HCQ6
uniprot id: A0A8M1MRG8
uniprot id: A0A8M1MTC8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ERG2 family.
messages: Cell junction
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum membrane
messages: Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Regulates calcium efflux at the endoplasmic reticulum.
messages: Homotrimer.
messages: Lipid droplet
messages: Membrane
messages: Nucleus envelope
messages: Nucleus inner membrane
messages: Nucleus outer membrane
messages: Postsynaptic density membrane
messages: The C-terminal helices form a flat, hydrophobic surface that is probably tightly associated with the cytosolic surface of the endoplasmic reticulum membrane.
messages: Vesicle
messages: growth cone

29088:NR5A2
gene id: 29088:NR5A2
uniprot id: A0A2Y9GGD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

29088:TLL1
gene id: 29088:TLL1
uniprot id: A0A2Y9HS13
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:NUDT6
gene id: 29088:NUDT6
uniprot id: A0A2Y9GDJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Cytoplasm
messages: May contribute to the regulation of cell proliferation.
messages: Mitochondrion
messages: Monomer and homodimer.
messages: Nucleus

29088:LOC110579754
gene id: 29088:LOC110579754
uniprot id: A0A2Y9H0J1
uniprot id: A0A2Y9H5B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

29088:CSNK1G2
gene id: 29088:CSNK1G2
uniprot id: A0A2Y9IBB3
uniprot id: A0A2Y9IBF9
uniprot id: A0A2Y9IFS3
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

29088:PI4K2B
gene id: 29088:PI4K2B
uniprot id: A0A2Y9G7R2
uniprot id: A0A2Y9G7Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

29088:MARVELD1
gene id: 29088:MARVELD1
uniprot id: A0A2Y9HUQ1
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110581945
gene id: 29088:LOC110581945
uniprot id: A0A8M1MLW1
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

29088:BACE2
gene id: 29088:BACE2
uniprot id: A0A2Y9G7B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Endosome
messages: Membrane

29088:WNT9A
gene id: 29088:WNT9A
uniprot id: A0A8M1MGM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

29088:TAF7L
gene id: 29088:TAF7L
uniprot id: A0A2Y9HI20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

29088:LOC110592054
gene id: 29088:LOC110592054
uniprot id: A0A2Y9I475
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

29088:IL19
gene id: 29088:IL19
uniprot id: A0A2Y9GGD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

29088:GPAM
gene id: 29088:GPAM
uniprot id: A0A2Y9HUP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipids biosynthesis such as triglycerides, phosphatidic acids and lysophosphatidic acids.
messages: Mitochondrion outer membrane

29088:SUSD6
gene id: 29088:SUSD6
uniprot id: A0A2Y9G8S3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:MVK
gene id: 29088:MVK
uniprot id: A0A2Y9IA08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis.
messages: Cytoplasm

29088:SPP2
gene id: 29088:SPP2
uniprot id: A0A2Y9GA81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPP2 family.
messages: Could coordinate an aspect of bone turnover.
messages: Secreted

29088:MS4A1
gene id: 29088:MS4A1
uniprot id: A0A2Y9GN48
names: Similarity
messages: Belongs to the MS4A family.

29088:SOHLH2
gene id: 29088:SOHLH2
uniprot id: A0A2Y9H411
names: Subcellular Location Annotation
messages: Nucleus

29088:SNAP25
gene id: 29088:SNAP25
uniprot id: A0A2Y9GZB6
uniprot id: A0A8M1MM52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Membrane
messages: Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A; this complex binds CPLX1. Found in a complex containing SYT1, SV2B and syntaxin-1. Found in a ternary complex with STX1A and VAMP8. Interacts with HSC70 and with SYT9, forming a complex with DNAJC5. The interaction with SYT9 is inhibited in presence of calcium. Isoform 1 and isoform 2 interact with BLOC1S6. Interacts with CENPF. Interacts with EQTN. Interacts with HGS. Interacts with KCNB1 (via N-terminus); reduces the voltage-dependent potassium channel KCNB1 activity in pancreatic beta cells. Interacts with OTOF. Interacts with RIMS1. Interacts with SNAPIN. Interacts with STXBP6. Interacts with TRIM9. Interacts with ZDHHC13 (via ANK repeats). Interacts with ZDHHC17 (via ANK repeats). Associates with the BLOC-1 complex. Interacts with PLCL1 (via C2 domain). Interacts with PRRT2; this interaction may impair the formation of the SNARE complex. Interacts with alpha-synuclein/SNCA. Interacts with PRPH2. Interacts with ROM1. Interacts with STX3.
messages: Photoreceptor inner segment
messages: synaptosome
messages: t-SNARE involved in the molecular regulation of neurotransmitter release. Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells.

29088:LOC110573282
gene id: 29088:LOC110573282
uniprot id: A0A8M1MXK6
names: Similarity
messages: Belongs to the intermediate filament family.

29088:EDN1
gene id: 29088:EDN1
uniprot id: A0A2Y9HLU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

29088:LOC110591666
gene id: 29088:LOC110591666
uniprot id: A0A8M1MQH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Monomer.
messages: Nucleus
messages: nucleolus

29088:SLA
gene id: 29088:SLA
uniprot id: A0A2Y9H4G0
names: Subcellular Location Annotation
messages: Cytoplasm

29088:ADAMTS10
gene id: 29088:ADAMTS10
uniprot id: A0A8M1MK69
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:LOC110590429
gene id: 29088:LOC110590429
uniprot id: A0A2Y9HZA1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

29088:DNTT
gene id: 29088:DNTT
uniprot id: A0A2Y9HUZ8
uniprot id: A0A2Y9I0C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Nucleus
messages: Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator.

29088:PDCD11
gene id: 29088:PDCD11
uniprot id: A0A8M1MHE4
names: Subcellular Location Annotation
messages: nucleolus

29088:LOC110589977
gene id: 29088:LOC110589977
uniprot id: A0A8M1MLV9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

29088:TGFB2
gene id: 29088:TGFB2
uniprot id: A0A2Y9HVZ6
uniprot id: A0A8M1MGL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

29088:CIBAR2
gene id: 29088:CIBAR2
uniprot id: A0A8M1MVX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CIBAR family.
messages: centriole
messages: cilium basal body

29088:CPEB2
gene id: 29088:CPEB2
uniprot id: A0A2Y9G7T8
uniprot id: A0A2Y9G814
uniprot id: A0A2Y9G862
uniprot id: A0A2Y9G866
uniprot id: A0A2Y9GAG8
uniprot id: A0A2Y9GAH7
uniprot id: A0A2Y9GBG1
uniprot id: A0A2Y9GBG4
uniprot id: A0A8M1M519
uniprot id: A0A8M1M5C2
uniprot id: A0A8M1M7G3
uniprot id: A0A8M1M8Y0
names: Similarity
messages: Belongs to the RRM CPEB family.

29088:LOC110594251
gene id: 29088:LOC110594251
uniprot id: A0A8M1M5Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 20 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

29088:LOC110577262
gene id: 29088:LOC110577262
uniprot id: A0A2Y9GSM9
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

29088:NETO1
gene id: 29088:NETO1
uniprot id: A0A8M1MV24
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110586472
gene id: 29088:LOC110586472
uniprot id: A0A8M1MEF1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Component of the 40S small ribosomal subunit.

29088:MGA
gene id: 29088:MGA
uniprot id: A0A2Y9HP92
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

29088:PLAA
gene id: 29088:PLAA
uniprot id: A0A2Y9GCC8
uniprot id: A0A2Y9GFA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PLAP family.
messages: Cytoplasm

29088:VPS33A
gene id: 29088:VPS33A
uniprot id: A0A2Y9HWW6
uniprot id: A0A8M1MTQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: clathrin-coated vesicle

29088:LOC110580448
gene id: 29088:LOC110580448
uniprot id: A0A2Y9H7I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
messages: Peroxisome

29088:ESYT3
gene id: 29088:ESYT3
uniprot id: A0A2Y9G6A1
uniprot id: A0A2Y9G6A2
uniprot id: A0A2Y9G8Q9
uniprot id: A0A2Y9G9T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:BVES
gene id: 29088:BVES
uniprot id: A0A2Y9HHY4
names: Similarity
messages: Belongs to the popeye family.

29088:VPS26C
gene id: 29088:VPS26C
uniprot id: A0A2Y9G658
uniprot id: A0A8M1M652
uniprot id: A0A8M1M6F3
names: Similarity
messages: Belongs to the VPS26 family.

29088:RAB29
gene id: 29088:RAB29
uniprot id: A0A2Y9GWS9
uniprot id: A0A2Y9GYD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

29088:DHX58
gene id: 29088:DHX58
uniprot id: A0A2Y9GIR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

29088:PGAP1
gene id: 29088:PGAP1
uniprot id: A0A2Y9I8R3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:LOC110576101
gene id: 29088:LOC110576101
uniprot id: A0A2Y9GSP5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110586096
gene id: 29088:LOC110586096
uniprot id: A0A2Y9HQE8
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

29088:PBX3
gene id: 29088:PBX3
uniprot id: A0A2Y9H5H0
uniprot id: A0A2Y9HAX6
uniprot id: A0A8M1MUB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

29088:KIF4A
gene id: 29088:KIF4A
uniprot id: A0A2Y9GAK7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:SFT2D2
gene id: 29088:SFT2D2
uniprot id: A0A2Y9GM96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

29088:ARID1B
gene id: 29088:ARID1B
uniprot id: A0A8M1MHY5
names: Subcellular Location Annotation
messages: Nucleus

29088:MEOX1
gene id: 29088:MEOX1
uniprot id: A0A2Y9GE18
uniprot id: A0A2Y9GH53
names: Subcellular Location Annotation
messages: Nucleus

29088:SV2B
gene id: 29088:SV2B
uniprot id: A0A2Y9GAZ5
uniprot id: A0A2Y9GB36
uniprot id: A0A2Y9GB51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

29088:NAAA
gene id: 29088:NAAA
uniprot id: A0A2Y9I227
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acid ceramidase family.
messages: Heterodimer.
messages: Lysosome

29088:PPP1R13B
gene id: 29088:PPP1R13B
uniprot id: A0A2Y9G967
uniprot id: A0A2Y9G9A2
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110582341
gene id: 29088:LOC110582341
uniprot id: A0A8M1MBI5
names: Similarity
messages: Belongs to the yippee family.

29088:GFRA2
gene id: 29088:GFRA2
uniprot id: A0A2Y9HS03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane
messages: Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.

29088:FLT3
gene id: 29088:FLT3
uniprot id: A0A2Y9G4X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

29088:TM4SF1
gene id: 29088:TM4SF1
uniprot id: A0A2Y9GQU6
uniprot id: A0A2Y9GR44
uniprot id: A0A8M1MDK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

29088:LIPG
gene id: 29088:LIPG
uniprot id: A0A2Y9GRW6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:OLFML3
gene id: 29088:OLFML3
uniprot id: A0A2Y9H8Z4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:GABRG2
gene id: 29088:GABRG2
uniprot id: A0A2Y9HQ43
uniprot id: A0A2Y9HWH3
uniprot id: A0A8M1MI67
uniprot id: A0A8M1MJI1
uniprot id: A0A8M1MPX0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG2 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:LOC110573343
gene id: 29088:LOC110573343
uniprot id: A0A2Y9GEP1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SCML1
gene id: 29088:SCML1
uniprot id: A0A2Y9GPS4
names: Similarity
messages: Belongs to the SCM family.

29088:LOC110574945
gene id: 29088:LOC110574945
uniprot id: A0A2Y9GNF0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

29088:DYDC1
gene id: 29088:DYDC1
uniprot id: A0A2Y9I0S8
uniprot id: A0A8M1MIJ1
names: Similarity
messages: Belongs to the dpy-30 family.

29088:DKK1
gene id: 29088:DKK1
uniprot id: A0A2Y9HJN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

29088:HSD17B3
gene id: 29088:HSD17B3
uniprot id: A0A2Y9G3Z7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29088:PTGS2
gene id: 29088:PTGS2
uniprot id: A0A2Y9GLL2
names: Caution
names: Similarity
messages: Belongs to the prostaglandin G/H synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110575479
gene id: 29088:LOC110575479
uniprot id: A0A8M1M0Q0
uniprot id: A0A8M1M393
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

29088:LYG1
gene id: 29088:LYG1
uniprot id: A0A2Y9HZ27
names: Similarity
messages: Belongs to the glycosyl hydrolase 23 family.

29088:MRPL14
gene id: 29088:MRPL14
uniprot id: A0A2Y9HES0
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

29088:BCKDK
gene id: 29088:BCKDK
uniprot id: A0A2Y9HXK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

29088:NHEJ1
gene id: 29088:NHEJ1
uniprot id: A0A2Y9I9D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XLF subfamily.
messages: Nucleus

29088:AP3S1
gene id: 29088:AP3S1
uniprot id: A0A2Y9I6F1
uniprot id: A0A8M1MGR5
uniprot id: A0A8M1MGR9
uniprot id: A0A8M1MIU8
uniprot id: A0A8M1MIV3
uniprot id: A0A8M1MK66
uniprot id: A0A8M1MQM0
uniprot id: A0A8M1MQM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

29088:TIMM10B
gene id: 29088:TIMM10B
uniprot id: A0A2Y9GU44
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

29088:GJB3
gene id: 29088:GJB3
uniprot id: A0A2Y9GKX9
uniprot id: A0A2Y9GL85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

29088:NAALADL2
gene id: 29088:NAALADL2
uniprot id: A0A2Y9I2R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Membrane

29088:MB21D2
gene id: 29088:MB21D2
uniprot id: A0A2Y9H9F5
names: Similarity
messages: Belongs to the mab-21 family.

29088:LOC110575364
gene id: 29088:LOC110575364
uniprot id: A0A2Y9GRX2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

29088:AKAP9
gene id: 29088:AKAP9
uniprot id: A0A8M1MTS2
names: Subcellular Location Annotation
messages: centrosome

29088:EBF4
gene id: 29088:EBF4
uniprot id: A0A2Y9GZR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

29088:CNPY1
gene id: 29088:CNPY1
uniprot id: A0A2Y9HH31
names: Similarity
messages: Belongs to the canopy family.

29088:FSCN3
gene id: 29088:FSCN3
uniprot id: A0A2Y9HU65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

29088:LOC123325523
gene id: 29088:LOC123325523
uniprot id: A0A2Y9GI84
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SERPINI2
gene id: 29088:SERPINI2
uniprot id: A0A2Y9I9W8
names: Similarity
messages: Belongs to the serpin family.

29088:FADS2
gene id: 29088:FADS2
uniprot id: A0A2Y9GPL9
uniprot id: A0A2Y9GTG8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

29088:TRAPPC2L
gene id: 29088:TRAPPC2L
uniprot id: A0A2Y9I271
uniprot id: A0A2Y9I2N9
uniprot id: A0A8M1MVS5
uniprot id: A0A8M1MX79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

29088:RITA1
gene id: 29088:RITA1
uniprot id: A0A2Y9HWR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RITA family.
messages: Cytoplasm
messages: Interacts with RBPJ/RBPSUH.
messages: Nucleus
messages: Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.

29088:PDRG1
gene id: 29088:PDRG1
uniprot id: A0A2Y9GZS4
uniprot id: A0A2Y9H664
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Component of the PAQosome complex which is responsible for the biogenesis of several protein complexes and which consists of R2TP complex members RUVBL1, RUVBL2, RPAP3 and PIH1D1, URI complex members PFDN2, PFDN6, PDRG1, UXT and URI1 as well as ASDURF, POLR2E and DNAAF10/WDR92.
messages: Cytoplasm
messages: May play a role in chaperone-mediated protein folding.

29088:CCNP
gene id: 29088:CCNP
uniprot id: A0A2Y9I353
names: Similarity
messages: Belongs to the cyclin family.

29088:CLNS1A
gene id: 29088:CLNS1A
uniprot id: A0A2Y9I992
uniprot id: A0A2Y9IFZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pICln (TC 1.A.47) family.
messages: Nucleus

29088:KMT5B
gene id: 29088:KMT5B
uniprot id: A0A2Y9GVI4
uniprot id: A0A8M1MR17
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

29088:C2
gene id: 29088:C2
uniprot id: A0A2Y9HMN9
uniprot id: A0A8M1MH77
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:ABCC5
gene id: 29088:ABCC5
uniprot id: A0A2Y9H965
names: Subcellular Location Annotation
messages: Membrane

29088:ARHGEF7
gene id: 29088:ARHGEF7
uniprot id: A0A8M1M6P6
uniprot id: A0A8M1M8U8
uniprot id: A0A8M1MA86
uniprot id: A0A8M1MEL7
names: Subcellular Location Annotation
messages: lamellipodium

29088:REM2
gene id: 29088:REM2
uniprot id: A0A2Y9HP61
names: Subcellular Location Annotation
messages: Cell membrane

29088:STK38L
gene id: 29088:STK38L
uniprot id: A0A2Y9H3E1
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:SCGB2A2
gene id: 29088:SCGB2A2
uniprot id: A0A2Y9GRZ0
names: Subcellular Location Annotation
messages: Secreted

29088:SLC25A38
gene id: 29088:SLC25A38
uniprot id: A0A2Y9IJJ7
uniprot id: A0A8M1MM18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Membrane
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis.
messages: Mitochondrion inner membrane
messages: Plays a role as pro-apoptotic protein that induces caspase-dependent apoptosis.

29088:SFN
gene id: 29088:SFN
uniprot id: A0A2Y9GPK0
names: Similarity
messages: Belongs to the 14-3-3 family.

29088:LOC110569800
gene id: 29088:LOC110569800
uniprot id: A0A2Y9G2V8
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

29088:RGS3
gene id: 29088:RGS3
uniprot id: A0A8M1MU16
uniprot id: A0A8M1MVE2
uniprot id: A0A8M1MYN6
names: Subcellular Location Annotation
messages: Cytoplasm

29088:LOC110576546
gene id: 29088:LOC110576546
uniprot id: A0A2Y9GQA9
uniprot id: A0A8M1MRL5
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

29088:CHMP4A
gene id: 29088:CHMP4A
uniprot id: A0A2Y9HN80
uniprot id: A0A8M1MJ47
names: Similarity
messages: Belongs to the SNF7 family.

29088:MTMR11
gene id: 29088:MTMR11
uniprot id: A0A8M1MAM4
uniprot id: A0A8M1MGK2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

29088:XPO6
gene id: 29088:XPO6
uniprot id: A0A2Y9HXL7
uniprot id: A0A2Y9I404
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

29088:OPTN
gene id: 29088:OPTN
uniprot id: A0A2Y9HKY4
uniprot id: A0A2Y9HRL9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Golgi apparatus
messages: May act by regulating membrane trafficking and cellular morphogenesis.
messages: Recycling endosome
messages: autophagosome
messages: perinuclear region
messages: trans-Golgi network

29088:ACSF2
gene id: 29088:ACSF2
uniprot id: A0A2Y9I892
uniprot id: A0A2Y9I8Z7
uniprot id: A0A2Y9IFN7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

29088:USP14
gene id: 29088:USP14
uniprot id: A0A2Y9GR73
uniprot id: A0A8M1MWL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase C19 family. USP14/UBP6 subfamily.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Homodimer (Potential). Associates with the 26S proteasome. Interacts with FANCC, CXCR4 and ERN1. Interacts with TRIM14; this interaction recruits USP14 to cleave ubiquitin chains of CGAS.

29088:LOC110571316
gene id: 29088:LOC110571316
uniprot id: A0A2Y9G7S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

29088:STT3B
gene id: 29088:STT3B
uniprot id: A0A2Y9G8W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

29088:ITGB4
gene id: 29088:ITGB4
uniprot id: A0A8M1MTZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

29088:SNX6
gene id: 29088:SNX6
uniprot id: A0A2Y9HHG1
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

29088:STAM2
gene id: 29088:STAM2
uniprot id: A0A2Y9IA51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane
messages: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.

29088:AGPAT3
gene id: 29088:AGPAT3
uniprot id: A0A2Y9G7G3
uniprot id: A0A2Y9GAW7
uniprot id: A0A2Y9GAX5
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

29088:CD48
gene id: 29088:CD48
uniprot id: A0A2Y9GEP2
uniprot id: A0A2Y9GET4
uniprot id: A0A2Y9GET6
names: Subcellular Location Annotation
messages: Membrane

29088:NAA35
gene id: 29088:NAA35
uniprot id: A0A2Y9G791
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. Involved in regulation of apoptosis and proliferation of smooth muscle cells.
messages: Belongs to the MAK10 family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.
messages: Cytoplasm

29088:PHLDA3
gene id: 29088:PHLDA3
uniprot id: A0A2Y9GL81
names: Subcellular Location Annotation
messages: Cytoplasm

29088:LOC110580282
gene id: 29088:LOC110580282
uniprot id: A0A2Y9H6Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ST3GAL4
gene id: 29088:ST3GAL4
uniprot id: A0A2Y9HJT7
uniprot id: A0A2Y9HK26
uniprot id: A0A8M1MRB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

29088:PTGES3L
gene id: 29088:PTGES3L
uniprot id: A0A8M1MV86
names: Similarity
messages: Belongs to the p23/wos2 family.

29088:KCNE3
gene id: 29088:KCNE3
uniprot id: A0A2Y9I8V4
names: Similarity
messages: Belongs to the potassium channel KCNE family.

29088:CCNE1
gene id: 29088:CCNE1
uniprot id: A0A2Y9HYI5
uniprot id: A0A2Y9HYW2
names: Similarity
messages: Belongs to the cyclin family.

29088:LOC110594052
gene id: 29088:LOC110594052
uniprot id: A0A2Y9IB59
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ACD
gene id: 29088:ACD
uniprot id: A0A2Y9I5T1
uniprot id: A0A8M1MW31
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

29088:FAM189A1
gene id: 29088:FAM189A1
uniprot id: A0A2Y9GAR9
names: Similarity
messages: Belongs to the ENTREP family.

29088:LOC110572141
gene id: 29088:LOC110572141
uniprot id: A0A2Y9GEU7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

29088:LOC110585025
gene id: 29088:LOC110585025
uniprot id: A0A8M1MHM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

29088:FSCN2
gene id: 29088:FSCN2
uniprot id: A0A2Y9GBP6
uniprot id: A0A2Y9GBX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

29088:LOC110570712
gene id: 29088:LOC110570712
uniprot id: A0A8M1MFK6
names: Similarity
messages: Belongs to the PRR23 family.

29088:TMEM120B
gene id: 29088:TMEM120B
uniprot id: A0A2Y9HWJ9
uniprot id: A0A2Y9HY81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

29088:LOC110590814
gene id: 29088:LOC110590814
uniprot id: A0A2Y9I006
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

29088:CTDP1
gene id: 29088:CTDP1
uniprot id: A0A2Y9GRC9
uniprot id: A0A2Y9GRM0
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

29088:TRPC3
gene id: 29088:TRPC3
uniprot id: A0A2Y9GDR9
uniprot id: A0A2Y9GGP8
uniprot id: A0A2Y9GI38
uniprot id: A0A8M1M476
names: Subcellular Location Annotation
messages: Membrane

29088:DNM1L
gene id: 29088:DNM1L
uniprot id: A0A2Y9H485
uniprot id: A0A2Y9H488
uniprot id: A0A2Y9H4B3
uniprot id: A0A2Y9H9L6
uniprot id: A0A2Y9HAY4
uniprot id: A0A8M1ME83
uniprot id: A0A8M1MKJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: Cytoplasm

29088:PDE5A
gene id: 29088:PDE5A
uniprot id: A0A2Y9GLT5
uniprot id: A0A2Y9GSC8
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

29088:TRIM46
gene id: 29088:TRIM46
uniprot id: A0A2Y9GEV7
names: Subcellular Location Annotation
messages: cytoskeleton

29088:LOC110576473
gene id: 29088:LOC110576473
uniprot id: A0A2Y9GVQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:UBE4B
gene id: 29088:UBE4B
uniprot id: A0A8M1M8W4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm
messages: The U-box domain is required for the ubiquitin protein ligase activity.
messages: Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. Also functions as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. Mediates 'Lys-48'-linked polyubiquitination of substrates.

29088:CEBPE
gene id: 29088:CEBPE
uniprot id: A0A2Y9HP79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

29088:LOC110575489
gene id: 29088:LOC110575489
uniprot id: A0A2Y9GLP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

29088:HEXD
gene id: 29088:HEXD
uniprot id: A0A2Y9GBK4
uniprot id: A0A2Y9GED7
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

29088:LOC110593197
gene id: 29088:LOC110593197
uniprot id: A0A2Y9IFD9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:APOL5
gene id: 29088:APOL5
uniprot id: A0A2Y9GW09
names: Similarity
messages: Belongs to the apolipoprotein L family.

29088:CPZ
gene id: 29088:CPZ
uniprot id: A0A2Y9G5A9
names: Caution
names: Similarity
messages: Belongs to the peptidase M14 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:TMEM205
gene id: 29088:TMEM205
uniprot id: A0A2Y9IA22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM205 family.
messages: Membrane

29088:LOC110585582
gene id: 29088:LOC110585582
uniprot id: A0A2Y9HP56
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

29088:MSX2
gene id: 29088:MSX2
uniprot id: A0A2Y9HXR8
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110576116
gene id: 29088:LOC110576116
uniprot id: A0A2Y9GUE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:MMUT
gene id: 29088:MMUT
uniprot id: A0A2Y9HCW3
names: Function
names: Similarity
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle.

29088:DHX9
gene id: 29088:DHX9
uniprot id: A0A2Y9GH19
uniprot id: A0A2Y9GKD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Nucleus

29088:VPS13A
gene id: 29088:VPS13A
uniprot id: A0A2Y9H0K1
uniprot id: A0A2Y9H0L3
uniprot id: A0A2Y9H6Y7
uniprot id: A0A8M1MV23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS13 family.
messages: Lipid droplet

29088:CRYGS
gene id: 29088:CRYGS
uniprot id: A0A2Y9H9P7
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

29088:LOC110580087
gene id: 29088:LOC110580087
uniprot id: A0A8M1MQE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

29088:SLC6A4
gene id: 29088:SLC6A4
uniprot id: A0A8M1MXM6
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110575272
gene id: 29088:LOC110575272
uniprot id: A0A8M1M1L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

29088:KIF2C
gene id: 29088:KIF2C
uniprot id: A0A2Y9GK88
uniprot id: A0A8M1MAA0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:CR2
gene id: 29088:CR2
uniprot id: A0A2Y9GGG4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:PRSS16
gene id: 29088:PRSS16
uniprot id: A0A2Y9HU81
names: Similarity
messages: Belongs to the peptidase S28 family.

29088:MRPL49
gene id: 29088:MRPL49
uniprot id: A0A2Y9GPR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

29088:NDUFV2
gene id: 29088:NDUFV2
uniprot id: A0A2Y9H0T8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.

29088:LOC110592180
gene id: 29088:LOC110592180
uniprot id: A0A2Y9I4H1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

29088:CBLB
gene id: 29088:CBLB
uniprot id: A0A2Y9H8G1
uniprot id: A0A2Y9H8N6
uniprot id: A0A2Y9HE70
uniprot id: A0A2Y9HF88
names: Domain
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

29088:INPP4A
gene id: 29088:INPP4A
uniprot id: A0A8M1MQA3
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

29088:GPR6
gene id: 29088:GPR6
uniprot id: A0A2Y9HC04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:OXA1L
gene id: 29088:OXA1L
uniprot id: A0A2Y9HHC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

29088:TMEM86A
gene id: 29088:TMEM86A
uniprot id: A0A2Y9GUI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

29088:SERPINC1
gene id: 29088:SERPINC1
uniprot id: A0A2Y9GM84
uniprot id: A0A8M1MDF6
uniprot id: A0A8M1MDK2
uniprot id: A0A8M1MFL7
uniprot id: A0A8M1MM41
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the serpin family.
messages: Forms protease inhibiting heterodimer with TMPRSS7.
messages: extracellular space

29088:LOC110582778
gene id: 29088:LOC110582778
uniprot id: A0A2Y9H9Q9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:ONECUT3
gene id: 29088:ONECUT3
uniprot id: A0A8M1M9B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

29088:SLC30A4
gene id: 29088:SLC30A4
uniprot id: A0A2Y9HHE6
uniprot id: A0A2Y9HNL1
uniprot id: A0A8M1MN38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

29088:VIL1
gene id: 29088:VIL1
uniprot id: A0A2Y9I9Q3
names: Similarity
messages: Belongs to the villin/gelsolin family.

29088:GABARAPL1
gene id: 29088:GABARAPL1
uniprot id: A0A2Y9HB24
names: Similarity
messages: Belongs to the ATG8 family.

29088:AP1S1
gene id: 29088:AP1S1
uniprot id: A0A2Y9HFK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: Membrane
messages: clathrin-coated pit

29088:ATG3
gene id: 29088:ATG3
uniprot id: A0A8M1M8C6
uniprot id: A0A8M1MBW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG3 family.
messages: Cytoplasm

29088:CALHM4
gene id: 29088:CALHM4
uniprot id: A0A2Y9HHX1
uniprot id: A0A8M1MHK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

29088:LOC110576880
gene id: 29088:LOC110576880
uniprot id: A0A2Y9HYR7
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

29088:LOC110588568
gene id: 29088:LOC110588568
uniprot id: A0A8M1MBL4
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

29088:CCDC39
gene id: 29088:CCDC39
uniprot id: A0A2Y9HFR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC39 family.
messages: cilium axoneme

29088:SLC43A1
gene id: 29088:SLC43A1
uniprot id: A0A2Y9GN09
uniprot id: A0A8M1MRJ1
names: Subcellular Location Annotation
messages: Membrane

29088:MAPKAPK3
gene id: 29088:MAPKAPK3
uniprot id: A0A2Y9GTE0
uniprot id: A0A2Y9GZ73
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:GLI2
gene id: 29088:GLI2
uniprot id: A0A8M1M9J8
uniprot id: A0A8M1MDU6
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

29088:TMEM256
gene id: 29088:TMEM256
uniprot id: A0A2Y9HFQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM256 family.
messages: Membrane

29088:ST8SIA2
gene id: 29088:ST8SIA2
uniprot id: A0A2Y9GB31
uniprot id: A0A2Y9GDQ7
uniprot id: A0A2Y9GF81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

29088:LOC110577561
gene id: 29088:LOC110577561
uniprot id: A0A2Y9GTN6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:VGLL4
gene id: 29088:VGLL4
uniprot id: A0A2Y9HFY8
uniprot id: A0A2Y9HG80
uniprot id: A0A2Y9HMA2
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

29088:CHRNA4
gene id: 29088:CHRNA4
uniprot id: A0A2Y9G2Y6
uniprot id: A0A2Y9G341
uniprot id: A0A8M1MLD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:PPIL3
gene id: 29088:PPIL3
uniprot id: A0A2Y9I4Q1
uniprot id: A0A2Y9I4U5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

29088:ADGRD1
gene id: 29088:ADGRD1
uniprot id: A0A2Y9HR73
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:MRPL28
gene id: 29088:MRPL28
uniprot id: A0A2Y9HQ70
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

29088:LOC110578425
gene id: 29088:LOC110578425
uniprot id: A0A2Y9GWL7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

29088:PTAFR
gene id: 29088:PTAFR
uniprot id: A0A2Y9GJE5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane

29088:ARSL
gene id: 29088:ARSL
uniprot id: A0A2Y9HS26
names: Similarity
messages: Belongs to the sulfatase family.

29088:MMD
gene id: 29088:MMD
uniprot id: A0A2Y9I719
uniprot id: A0A8M1MZ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

29088:B3GNT6
gene id: 29088:B3GNT6
uniprot id: A0A2Y9IG73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:LOC110573047
gene id: 29088:LOC110573047
uniprot id: A0A2Y9G615
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

29088:PTTG1
gene id: 29088:PTTG1
uniprot id: A0A2Y9HPH1
uniprot id: A0A2Y9HUQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the securin family.
messages: Cytoplasm
messages: Nucleus

29088:LOC110588627
gene id: 29088:LOC110588627
uniprot id: A0A2Y9HSU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

29088:SELENOK
gene id: 29088:SELENOK
uniprot id: A0A2Y9HGH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenoprotein K family.
messages: Endoplasmic reticulum membrane

29088:TYSND1
gene id: 29088:TYSND1
uniprot id: A0A8M1MEZ6
uniprot id: A0A8M1MH41
uniprot id: A0A8M1MNR5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1B family.
messages: Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.
messages: Peroxisome
messages: The full-lengh TYSND1 is the active the proteolytic processing of PTS1- and PTS2-proteins and in self-cleavage, and intermolecular self-cleavage of TYSND1 down-regulates its protease activity.

29088:FGF13
gene id: 29088:FGF13
uniprot id: A0A8M1M0Y4
uniprot id: A0A8M1M3H0
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

29088:HMGN2
gene id: 29088:HMGN2
uniprot id: A0A2Y9GPJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

29088:CCDC25
gene id: 29088:CCDC25
uniprot id: A0A2Y9HRU3
uniprot id: A0A2Y9HX62
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC25 family.
messages: Cell membrane
messages: Endomembrane system
messages: Interacts (via cytoplasmic region) with ILK.

29088:LOC110592575
gene id: 29088:LOC110592575
uniprot id: A0A2Y9IAI9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

29088:LONP2
gene id: 29088:LONP2
uniprot id: A0A2Y9IC45
uniprot id: A0A8M1MZF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta-oxidation through degradation of the self-processed forms of TYSND1.
messages: Belongs to the peptidase S16 family.
messages: Interacts with PEX5. Interacts with TYSND1.
messages: Peroxisome matrix

29088:LOC110583638
gene id: 29088:LOC110583638
uniprot id: A0A2Y9HC77
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:PTPRU
gene id: 29088:PTPRU
uniprot id: A0A2Y9GLU5
uniprot id: A0A8M1M7M9
uniprot id: A0A8M1M7W6
uniprot id: A0A8M1MA25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

29088:NOTUM
gene id: 29088:NOTUM
uniprot id: A0A2Y9GFZ3
names: Similarity
messages: Belongs to the pectinacetylesterase family. Notum subfamily.

29088:FSCN1
gene id: 29088:FSCN1
uniprot id: A0A2Y9GDQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

29088:LOC110583893
gene id: 29088:LOC110583893
uniprot id: A0A2Y9HCZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

29088:SLC25A53
gene id: 29088:SLC25A53
uniprot id: A0A2Y9G4B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:RASSF5
gene id: 29088:RASSF5
uniprot id: A0A2Y9GSG6
names: Subcellular Location Annotation
messages: cytoskeleton

29088:NUP155
gene id: 29088:NUP155
uniprot id: A0A2Y9HJX2
uniprot id: A0A8M1MGC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.
messages: nuclear pore complex

29088:SNUPN
gene id: 29088:SNUPN
uniprot id: A0A2Y9HIU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snurportin family.
messages: Cytoplasm
messages: Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
messages: Nucleus

29088:LOC110570286
gene id: 29088:LOC110570286
uniprot id: A0A2Y9HKK2
names: Similarity
messages: Belongs to the GroES chaperonin family.

29088:LOC110577962
gene id: 29088:LOC110577962
uniprot id: A0A2Y9GUR8
uniprot id: A0A8M1MGE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

29088:QKI
gene id: 29088:QKI
uniprot id: A0A8M1MLB1
names: Function
names: Subunit
messages: Homodimer. Does not require RNA to homodimerize. Able to heterodimerize with BICC1.
messages: RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor.

29088:MRPL46
gene id: 29088:MRPL46
uniprot id: A0A2Y9GB56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL46 family.
messages: Mitochondrion

29088:TGM6
gene id: 29088:TGM6
uniprot id: A0A2Y9H0A0
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

29088:TIMM8A
gene id: 29088:TIMM8A
uniprot id: A0A2Y9HIC0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

29088:EPHA1
gene id: 29088:EPHA1
uniprot id: A0A2Y9HA62
uniprot id: A0A2Y9HFZ7
uniprot id: A0A2Y9HGS2
names: Subcellular Location Annotation
messages: Membrane

29088:ANXA4
gene id: 29088:ANXA4
uniprot id: A0A2Y9HZG8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Zymogen granule membrane

29088:RPRD2
gene id: 29088:RPRD2
uniprot id: A0A2Y9H375
uniprot id: A0A8M1M8H9
uniprot id: A0A8M1M8I2
uniprot id: A0A8M1MAN6
uniprot id: A0A8M1MC16
uniprot id: A0A8M1MGL6
names: Similarity
messages: Belongs to the UPF0400 (RTT103) family.

29088:CD34
gene id: 29088:CD34
uniprot id: A0A2Y9GJN4
uniprot id: A0A2Y9GLC8
names: Subcellular Location Annotation
messages: Membrane

29088:AHDC1
gene id: 29088:AHDC1
uniprot id: A0A2Y9GKY6
names: Subcellular Location Annotation
messages: Nucleus

29088:CXCL9
gene id: 29088:CXCL9
uniprot id: A0A2Y9I2W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

29088:PRPF31
gene id: 29088:PRPF31
uniprot id: A0A2Y9GG11
uniprot id: A0A8M1MX65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP31 family.
messages: Cajal body

29088:SAP18
gene id: 29088:SAP18
uniprot id: A0A2Y9G804
names: Similarity
messages: Belongs to the SAP18 family.

29088:OSBPL3
gene id: 29088:OSBPL3
uniprot id: A0A2Y9H168
uniprot id: A0A2Y9H1B3
uniprot id: A0A2Y9H1C9
uniprot id: A0A2Y9H7S1
names: Similarity
messages: Belongs to the OSBP family.

29088:LOC123323378
gene id: 29088:LOC123323378
uniprot id: A0A8M1M518
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS21 family.

29088:TMEM175
gene id: 29088:TMEM175
uniprot id: A0A2Y9G307
uniprot id: A0A8M1M7J3
uniprot id: A0A8M1M909
uniprot id: A0A8M1MD81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

29088:GCNT3
gene id: 29088:GCNT3
uniprot id: A0A2Y9HD91
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

29088:SUMO2
gene id: 29088:SUMO2
uniprot id: A0A2Y9GF87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

29088:CLUL1
gene id: 29088:CLUL1
uniprot id: A0A2Y9GVH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Secreted

29088:ELL2
gene id: 29088:ELL2
uniprot id: A0A2Y9I0H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

29088:LOC110578449
gene id: 29088:LOC110578449
uniprot id: A0A2Y9GWE2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SKA3
gene id: 29088:SKA3
uniprot id: A0A2Y9G7W6
uniprot id: A0A8M1MDQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA3 family.
messages: kinetochore
messages: spindle

29088:FMNL3
gene id: 29088:FMNL3
uniprot id: A0A2Y9I9Q2
uniprot id: A0A8M1MA83
uniprot id: A0A8M1MCK5
names: Similarity
messages: Belongs to the formin homology family.

29088:TMEM176A
gene id: 29088:TMEM176A
uniprot id: A0A2Y9H9Z0
names: Similarity
messages: Belongs to the TMEM176 family.

29088:FAM219B
gene id: 29088:FAM219B
uniprot id: A0A2Y9HCS6
uniprot id: A0A2Y9HJA8
names: Similarity
messages: Belongs to the FAM219 family.

29088:MET
gene id: 29088:MET
uniprot id: A0A2Y9HTP5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:PSPC1
gene id: 29088:PSPC1
uniprot id: A0A2Y9G4Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PSPC family.
messages: Cytoplasm
messages: Nucleus matrix
messages: Nucleus speckle
messages: nucleolus

29088:TMPRSS7
gene id: 29088:TMPRSS7
uniprot id: A0A8M1M8B2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:TNKS2
gene id: 29088:TNKS2
uniprot id: A0A2Y9HUD1
uniprot id: A0A8M1MDV9
names: Function
names: Similarity
messages: Belongs to the ARTD/PARP family.
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

29088:VPS35L
gene id: 29088:VPS35L
uniprot id: A0A2Y9HWJ2
uniprot id: A0A8M1MCJ4
uniprot id: A0A8M1MCP3
uniprot id: A0A8M1MG61
uniprot id: A0A8M1ML55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS35L family.
messages: Endosome

29088:P2RX1
gene id: 29088:P2RX1
uniprot id: A0A2Y9ICD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

29088:MAP4
gene id: 29088:MAP4
uniprot id: A0A8M1MZ79
names: Subcellular Location Annotation
messages: cytoskeleton

29088:GPR3
gene id: 29088:GPR3
uniprot id: A0A2Y9GJD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:RPAP1
gene id: 29088:RPAP1
uniprot id: A0A2Y9HPB9
names: Similarity
messages: Belongs to the RPAP1 family.

29088:TMEM161A
gene id: 29088:TMEM161A
uniprot id: A0A2Y9GLC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

29088:LTA4H
gene id: 29088:LTA4H
uniprot id: A0A2Y9GUX4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

29088:LOC110573323
gene id: 29088:LOC110573323
uniprot id: A0A2Y9GHM0
names: Similarity
messages: Belongs to the intermediate filament family.

29088:FBN2
gene id: 29088:FBN2
uniprot id: A0A2Y9I0U3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibrillin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:MED28
gene id: 29088:MED28
uniprot id: A0A2Y9G7P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 28 family.
messages: Nucleus

29088:SLC4A2
gene id: 29088:SLC4A2
uniprot id: A0A2Y9HGB2
uniprot id: A0A8M1MQI5
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

29088:LOC110575275
gene id: 29088:LOC110575275
uniprot id: A0A8M1MHP7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

29088:SPX
gene id: 29088:SPX
uniprot id: A0A2Y9HA22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spexin family.
messages: Secreted

29088:UGGT2
gene id: 29088:UGGT2
uniprot id: A0A2Y9HQC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

29088:LOC110574536
gene id: 29088:LOC110574536
uniprot id: A0A2Y9GNJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:PRR15L
gene id: 29088:PRR15L
uniprot id: A0A2Y9I7M2
names: Similarity
messages: Belongs to the PRR15 family.

29088:MAP3K21
gene id: 29088:MAP3K21
uniprot id: A0A8M1MF02
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

29088:ICMT
gene id: 29088:ICMT
uniprot id: A0A2Y9GIR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:PRDM12
gene id: 29088:PRDM12
uniprot id: A0A2Y9H6E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Involved in the positive regulation of histone H3-K9 dimethylation.
messages: Nucleus

29088:ITGB5
gene id: 29088:ITGB5
uniprot id: A0A2Y9H988
uniprot id: A0A2Y9H9C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

29088:YPEL3
gene id: 29088:YPEL3
uniprot id: A0A2Y9HWT9
names: Similarity
messages: Belongs to the yippee family.

29088:PGPEP1
gene id: 29088:PGPEP1
uniprot id: A0A2Y9GHZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

29088:NNMT
gene id: 29088:NNMT
uniprot id: A0A2Y9HQW1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

29088:DARS2
gene id: 29088:DARS2
uniprot id: A0A2Y9GGK6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

29088:SUOX
gene id: 29088:SUOX
uniprot id: A0A2Y9GUE0
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the oxidation of sulfite to sulfate, the terminal reaction in the oxidative degradation of sulfur-containing amino acids.
messages: Mitochondrion intermembrane space

29088:NIBAN3
gene id: 29088:NIBAN3
uniprot id: A0A2Y9GI32
uniprot id: A0A8M1MRV2
names: Similarity
messages: Belongs to the Niban family.

29088:BAZ1A
gene id: 29088:BAZ1A
uniprot id: A0A2Y9HI24
uniprot id: A0A2Y9HIF6
uniprot id: A0A2Y9HP71
uniprot id: A0A8M1MMK5
names: Subcellular Location Annotation
messages: Nucleus

29088:SNRPB
gene id: 29088:SNRPB
uniprot id: A0A2Y9GZD9
uniprot id: A0A8M1ML50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP SmB/SmN family.
messages: Nucleus

29088:PDE7A
gene id: 29088:PDE7A
uniprot id: A0A2Y9H1C3
uniprot id: A0A8M1MGU3
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

29088:MRE11
gene id: 29088:MRE11
uniprot id: A0A8M1MPU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRE11/RAD32 family.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
messages: Nucleus

29088:CACFD1
gene id: 29088:CACFD1
uniprot id: A0A2Y9H5M9
uniprot id: A0A8M1MYN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel flower family.
messages: Membrane

29088:ANAPC2
gene id: 29088:ANAPC2
uniprot id: A0A2Y9H4Z0
uniprot id: A0A2Y9H4Z1
names: Similarity
messages: Belongs to the cullin family.

29088:LOC110588464
gene id: 29088:LOC110588464
uniprot id: A0A8M1M4P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane
messages: Oxidizes L-gulono-1,4-lactone to hydrogen peroxide and L-xylo-hexulonolactone which spontaneously isomerizes to L-ascorbate.

29088:LOC110585911
gene id: 29088:LOC110585911
uniprot id: A0A2Y9HJ93
uniprot id: A0A2Y9HJ95
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:HOMER2
gene id: 29088:HOMER2
uniprot id: A0A2Y9GE76
names: Subcellular Location Annotation
messages: Cytoplasm

29088:CDC5L
gene id: 29088:CDC5L
uniprot id: A0A2Y9H871
uniprot id: A0A2Y9HET4
uniprot id: A0A8M1MKJ4
names: Similarity
messages: Belongs to the CEF1 family.

29088:HNF1A
gene id: 29088:HNF1A
uniprot id: A0A2Y9I5E7
uniprot id: A0A2Y9I668
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

29088:ZNF622
gene id: 29088:ZNF622
uniprot id: A0A2Y9I2J3
uniprot id: A0A2Y9I2T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the REI1 family.
messages: Cytoplasm

29088:H1-2
gene id: 29088:H1-2
uniprot id: A0A8M1MI52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

29088:SLC12A8
gene id: 29088:SLC12A8
uniprot id: A0A8M1MRG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

29088:HCST
gene id: 29088:HCST
uniprot id: A0A2Y9HY46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAP10 family.
messages: Membrane

29088:DLAT
gene id: 29088:DLAT
uniprot id: A0A2Y9HK67
uniprot id: A0A8M1MMN3
uniprot id: A0A8M1MMN5
uniprot id: A0A8M1MMN7
uniprot id: A0A8M1MMP0
uniprot id: A0A8M1MMP2
uniprot id: A0A8M1MPM4
uniprot id: A0A8M1MPM9
uniprot id: A0A8M1MQY4
uniprot id: A0A8M1MWU2
uniprot id: A0A8M1MWU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Binds 2 lipoyl cofactors covalently.
messages: Mitochondrion matrix
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

29088:CD6
gene id: 29088:CD6
uniprot id: A0A2Y9GTI9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110590339
gene id: 29088:LOC110590339
uniprot id: A0A2Y9HYR7
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

29088:SPARCL1
gene id: 29088:SPARCL1
uniprot id: A0A2Y9I2D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPARC family.
messages: extracellular matrix

29088:THBS1
gene id: 29088:THBS1
uniprot id: A0A2Y9HIF8
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110581197
gene id: 29088:LOC110581197
uniprot id: A0A2Y9H4R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:RUNX1
gene id: 29088:RUNX1
uniprot id: A0A2Y9G3X8
uniprot id: A0A8M1MNE6
uniprot id: A0A8M1MXD4
names: Function
names: Subcellular Location Annotation
messages: Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
messages: Nucleus

29088:FHIP1B
gene id: 29088:FHIP1B
uniprot id: A0A2Y9GQB3
uniprot id: A0A8M1MPG8
uniprot id: A0A8M1MXY2
names: Similarity
messages: Belongs to the FHIP family.

29088:TAT
gene id: 29088:TAT
uniprot id: A0A2Y9I4K1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.

29088:ELF2
gene id: 29088:ELF2
uniprot id: A0A2Y9G7T9
uniprot id: A0A2Y9G800
uniprot id: A0A2Y9GA97
uniprot id: A0A2Y9GB97
uniprot id: A0A8M1M4M0
uniprot id: A0A8M1M4X4
uniprot id: A0A8M1M8J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

29088:PPCS
gene id: 29088:PPCS
uniprot id: A0A2Y9GJW7
uniprot id: A0A2Y9GK36
uniprot id: A0A2Y9GNF7
names: Similarity
messages: Belongs to the PPC synthetase family.

29088:SFXN1
gene id: 29088:SFXN1
uniprot id: A0A2Y9HRE1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

29088:PKP1
gene id: 29088:PKP1
uniprot id: A0A2Y9GLY4
names: Similarity
messages: Belongs to the beta-catenin family.

29088:CCDC172
gene id: 29088:CCDC172
uniprot id: A0A2Y9I2N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC172 family.
messages: Cytoplasm

29088:NDUFAB1
gene id: 29088:NDUFAB1
uniprot id: A0A2Y9GTB1
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

29088:LOC110571881
gene id: 29088:LOC110571881
uniprot id: A0A2Y9G9S1
uniprot id: A0A2Y9GCF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

29088:LOC110584307
gene id: 29088:LOC110584307
uniprot id: A0A2Y9HE20
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

29088:LOC110584340
gene id: 29088:LOC110584340
uniprot id: A0A2Y9HE92
names: Similarity
messages: Belongs to the SPATA31 family.

29088:LOC110593801
gene id: 29088:LOC110593801
uniprot id: A0A2Y9IHG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:FOXO3
gene id: 29088:FOXO3
uniprot id: A0A2Y9HCJ4
names: Subcellular Location Annotation
messages: Nucleus

29088:SLC8A2
gene id: 29088:SLC8A2
uniprot id: A0A2Y9GCT4
uniprot id: A0A2Y9GFS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

29088:TRADD
gene id: 29088:TRADD
uniprot id: A0A2Y9I7E9
uniprot id: A0A2Y9IBF3
names: Subcellular Location Annotation
messages: Nucleus
messages: cytoskeleton

29088:CDK6
gene id: 29088:CDK6
uniprot id: A0A2Y9H122
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:TSPAN7
gene id: 29088:TSPAN7
uniprot id: A0A2Y9GEH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

29088:FAM83F
gene id: 29088:FAM83F
uniprot id: A0A2Y9GVZ4
names: Similarity
messages: Belongs to the FAM83 family.

29088:LOC110572802
gene id: 29088:LOC110572802
uniprot id: A0A8M1M4Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane

29088:METTL26
gene id: 29088:METTL26
uniprot id: A0A2Y9HQG2
uniprot id: A0A2Y9HVD4
uniprot id: A0A2Y9HWX1
uniprot id: A0A8M1MAS6
uniprot id: A0A8M1MB05
names: Similarity
messages: Belongs to the UPF0585 family.

29088:POLR1B
gene id: 29088:POLR1B
uniprot id: A0A2Y9HT65
uniprot id: A0A2Y9HUJ7
uniprot id: A0A8M1MV17
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.

29088:SLC7A10
gene id: 29088:SLC7A10
uniprot id: A0A2Y9HYH1
names: Subcellular Location Annotation
messages: Membrane

29088:CREBL2
gene id: 29088:CREBL2
uniprot id: A0A2Y9H3R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Nucleus

29088:CACNA1A
gene id: 29088:CACNA1A
uniprot id: A0A8M1M5D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q-type calcium currents.

29088:CHST11
gene id: 29088:CHST11
uniprot id: A0A2Y9GZQ1
uniprot id: A0A2Y9H1F5
uniprot id: A0A8M1MD82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:LOC110584232
gene id: 29088:LOC110584232
uniprot id: A0A2Y9HK19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

29088:ACTN1
gene id: 29088:ACTN1
uniprot id: A0A8M1MJJ4
names: Similarity
messages: Belongs to the alpha-actinin family.

29088:LOC110581189
gene id: 29088:LOC110581189
uniprot id: A0A2Y9H4R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110573352
gene id: 29088:LOC110573352
uniprot id: A0A2Y9GHP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:DUXA
gene id: 29088:DUXA
uniprot id: A0A2Y9GKI2
names: Subcellular Location Annotation
messages: Nucleus

29088:PRUNE1
gene id: 29088:PRUNE1
uniprot id: A0A2Y9GWY3
names: Similarity
messages: Belongs to the PPase class C family. Prune subfamily.

29088:LOC123326387
gene id: 29088:LOC123326387
uniprot id: A0A8M1MY76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:NID2
gene id: 29088:NID2
uniprot id: A0A2Y9HZ53
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

29088:FGF12
gene id: 29088:FGF12
uniprot id: A0A2Y9H8V7
uniprot id: A0A2Y9H8Z8
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

29088:LOC110576250
gene id: 29088:LOC110576250
uniprot id: A0A2Y9GNZ7
uniprot id: A0A2Y9GP69
uniprot id: A0A2Y9GPA6
uniprot id: A0A2Y9GT26
names: Similarity
messages: Belongs to the LDH/MDH superfamily.
messages: Belongs to the LDH/MDH superfamily. LDH family.

29088:BHMT2
gene id: 29088:BHMT2
uniprot id: A0A2Y9HVI2
uniprot id: A0A2Y9HVJ0
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

29088:METTL1
gene id: 29088:METTL1
uniprot id: A0A2Y9GYV1
uniprot id: A0A8M1MCD6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with WDR4.
messages: Nucleus
messages: Phosphorylation at Ser-28 inactivates its catalytic activity but does not affect the interaction with WDR4.

29088:SPATA6
gene id: 29088:SPATA6
uniprot id: A0A8M1M7N3
names: Similarity
messages: Belongs to the SPATA6 family.

29088:LOC110570654
gene id: 29088:LOC110570654
uniprot id: A0A8M1MVX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA3 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Membrane
messages: Mitochondrion inner membrane

29088:NETO2
gene id: 29088:NETO2
uniprot id: A0A2Y9IIX3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:DIABLO
gene id: 29088:DIABLO
uniprot id: A0A2Y9HR49
uniprot id: A0A2Y9HRK1
uniprot id: A0A8M1MSW8
names: Subcellular Location Annotation
messages: Mitochondrion

29088:SCUBE3
gene id: 29088:SCUBE3
uniprot id: A0A8M1ML51
uniprot id: A0A8M1MRN8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:ZC3HAV1
gene id: 29088:ZC3HAV1
uniprot id: A0A8M1MPZ3
names: Similarity
messages: Belongs to the ARTD/PARP family.

29088:LHFPL4
gene id: 29088:LHFPL4
uniprot id: A0A2Y9HGJ2
names: Subcellular Location Annotation
messages: Membrane

29088:SLC35F4
gene id: 29088:SLC35F4
uniprot id: A0A2Y9I6G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

29088:STAC
gene id: 29088:STAC
uniprot id: A0A2Y9G2E3
names: Subcellular Location Annotation
messages: sarcolemma

29088:LOC110593425
gene id: 29088:LOC110593425
uniprot id: A0A8M1MN34
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

29088:LOC123325694
gene id: 29088:LOC123325694
uniprot id: A0A8M1MJE4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:SEMA3C
gene id: 29088:SEMA3C
uniprot id: A0A2Y9H7D1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:SLC66A2
gene id: 29088:SLC66A2
uniprot id: A0A2Y9GSB9
uniprot id: A0A2Y9GW85
names: Subcellular Location Annotation
messages: Membrane

29088:ITGB8
gene id: 29088:ITGB8
uniprot id: A0A2Y9H1M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Melanosome
messages: Membrane
messages: Recycling endosome
messages: focal adhesion
messages: invadopodium membrane
messages: lamellipodium
messages: ruffle membrane

29088:GORAB
gene id: 29088:GORAB
uniprot id: A0A2Y9GLR4
names: Similarity
messages: Belongs to the GORAB family.

29088:PDIA2
gene id: 29088:PDIA2
uniprot id: A0A2Y9HVJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

29088:TELO2
gene id: 29088:TELO2
uniprot id: A0A2Y9HPX7
uniprot id: A0A2Y9HV69
names: Similarity
messages: Belongs to the TEL2 family.

29088:LOC110570414
gene id: 29088:LOC110570414
uniprot id: A0A8M1MZ03
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

29088:FHIP1A
gene id: 29088:FHIP1A
uniprot id: A0A2Y9HSG4
names: Similarity
messages: Belongs to the FHIP family.

29088:ZNF75A
gene id: 29088:ZNF75A
uniprot id: A0A8M1MCJ8
uniprot id: A0A8M1MG16
uniprot id: A0A8M1ML00
names: Subcellular Location Annotation
messages: Nucleus

29088:ZDHHC3
gene id: 29088:ZDHHC3
uniprot id: A0A2Y9GIB4
uniprot id: A0A2Y9GLR7
uniprot id: A0A8M1MV81
uniprot id: A0A8M1MXN5
uniprot id: A0A8M1MXN8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

29088:SLC6A15
gene id: 29088:SLC6A15
uniprot id: A0A2Y9GZD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A15 subfamily.
messages: Membrane

29088:ABCA3
gene id: 29088:ABCA3
uniprot id: A0A2Y9HPJ9
names: Subcellular Location Annotation
messages: Membrane

29088:SIDT2
gene id: 29088:SIDT2
uniprot id: A0A2Y9HJU0
uniprot id: A0A2Y9HR69
uniprot id: A0A8M1MPK9
uniprot id: A0A8M1MQW9
uniprot id: A0A8M1MWT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SID1 family.
messages: Membrane

29088:SLC30A3
gene id: 29088:SLC30A3
uniprot id: A0A2Y9HNB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

29088:ATP10B
gene id: 29088:ATP10B
uniprot id: A0A8M1MQQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

29088:PSMA4
gene id: 29088:PSMA4
uniprot id: A0A2Y9GB81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

29088:PRKAA1
gene id: 29088:PRKAA1
uniprot id: A0A2Y9HK62
uniprot id: A0A2Y9HRW6
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

29088:CRBN
gene id: 29088:CRBN
uniprot id: A0A2Y9HG53
uniprot id: A0A2Y9HGD9
uniprot id: A0A2Y9HMG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRBN family.
messages: Nucleus

29088:EIF3H
gene id: 29088:EIF3H
uniprot id: A0A2Y9H214
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with RNF139; the interaction leads to protein translation inhibitions in a ubiquitination-dependent manner.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm

29088:SIN3B
gene id: 29088:SIN3B
uniprot id: A0A2Y9GLV5
names: Subcellular Location Annotation
messages: Nucleus

29088:DEDD2
gene id: 29088:DEDD2
uniprot id: A0A2Y9H8H5
uniprot id: A0A2Y9HF28
names: Subcellular Location Annotation
messages: nucleolus

29088:ADCY5
gene id: 29088:ADCY5
uniprot id: A0A8M1MR43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

29088:ANKRD34A
gene id: 29088:ANKRD34A
uniprot id: A0A2Y9H397
names: Similarity
messages: Belongs to the ANKRD34 family.

29088:LOC110593804
gene id: 29088:LOC110593804
uniprot id: A0A2Y9IA71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:MAML3
gene id: 29088:MAML3
uniprot id: A0A8M1M726
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

29088:MAP3K5
gene id: 29088:MAP3K5
uniprot id: A0A2Y9HAY3
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

29088:DYNLL1
gene id: 29088:DYNLL1
uniprot id: A0A2Y9I5X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

29088:MAGI2
gene id: 29088:MAGI2
uniprot id: A0A8M1MSI2
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110576476
gene id: 29088:LOC110576476
uniprot id: A0A2Y9GQ45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:MLLT11
gene id: 29088:MLLT11
uniprot id: A0A2Y9H3D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLLT11 family.
messages: Nucleus
messages: centrosome

29088:ELAVL2
gene id: 29088:ELAVL2
uniprot id: A0A2Y9GCB9
uniprot id: A0A2Y9GCC3
uniprot id: A0A2Y9GCG9
uniprot id: A0A2Y9GCI7
uniprot id: A0A2Y9GF96
uniprot id: A0A2Y9GGT0
uniprot id: A0A8M1MRB4
names: Similarity
messages: Belongs to the RRM elav family.

29088:ST8SIA6
gene id: 29088:ST8SIA6
uniprot id: A0A2Y9HST0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

29088:CDH7
gene id: 29088:CDH7
uniprot id: A0A2Y9GS56
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

29088:ACE2
gene id: 29088:ACE2
uniprot id: A0A2Y9GBR2
uniprot id: A0A2Y9GEI9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Secreted
messages: cilium

29088:KCNJ8
gene id: 29088:KCNJ8
uniprot id: A0A2Y9H3W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

29088:POU6F1
gene id: 29088:POU6F1
uniprot id: A0A2Y9I983
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

29088:PARP9
gene id: 29088:PARP9
uniprot id: A0A8M1MSQ8
names: Similarity
messages: Belongs to the ARTD/PARP family.

29088:LOC110571752
gene id: 29088:LOC110571752
uniprot id: A0A8M1M1F6
names: Subcellular Location Annotation
messages: Nucleus

29088:MED24
gene id: 29088:MED24
uniprot id: A0A2Y9I8A2
uniprot id: A0A2Y9ICY4
uniprot id: A0A8M1MVE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 24 family.
messages: Nucleus

29088:NANOG
gene id: 29088:NANOG
uniprot id: A0A2Y9H9B4
uniprot id: A0A2Y9HAR4
names: Subcellular Location Annotation
messages: Nucleus

29088:SMARCD2
gene id: 29088:SMARCD2
uniprot id: A0A2Y9G7P9
names: Similarity
messages: Belongs to the SMARCD family.

29088:CLU
gene id: 29088:CLU
uniprot id: A0A2Y9HSZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Antiparallel disulfide-linked heterodimer of an alpha chain and a beta chain. Self-associates and forms higher oligomers.
messages: Belongs to the clusterin family.
messages: Endoplasmic reticulum
messages: Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins.
messages: Membrane
messages: Microsome
messages: Mitochondrion membrane
messages: Nucleus
messages: Secreted
messages: chromaffin granule
messages: cytosol
messages: perinuclear region

29088:CUL2
gene id: 29088:CUL2
uniprot id: A0A2Y9GV19
uniprot id: A0A2Y9GWP8
names: Similarity
messages: Belongs to the cullin family.

29088:ATP5MC2
gene id: 29088:ATP5MC2
uniprot id: A0A2Y9GT56
uniprot id: A0A8M1MIM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

29088:JRKL
gene id: 29088:JRKL
uniprot id: A0A2Y9G999
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110588369
gene id: 29088:LOC110588369
uniprot id: A0A8M1M435
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

29088:EIF1AD
gene id: 29088:EIF1AD
uniprot id: A0A2Y9GTP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EIF1AD family.
messages: Interacts with GAPDH and STAT1.
messages: Plays a role into cellular response to oxidative stress. Decreases cell proliferation.

29088:TBC1D24
gene id: 29088:TBC1D24
uniprot id: A0A2Y9HQ79
uniprot id: A0A8M1MD55
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasmic vesicle membrane
messages: Interacts with ARF6.
messages: Membrane
messages: Presynapse

29088:POLL
gene id: 29088:POLL
uniprot id: A0A2Y9HVR7
uniprot id: A0A8M1MDY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus

29088:LOC110590226
gene id: 29088:LOC110590226
uniprot id: A0A2Y9HYD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM187 family.
messages: Membrane

29088:ERBB4
gene id: 29088:ERBB4
uniprot id: A0A2Y9I403
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

29088:ELOVL5
gene id: 29088:ELOVL5
uniprot id: A0A8M1MSJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL5 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: dendrite

29088:SDR42E2
gene id: 29088:SDR42E2
uniprot id: A0A2Y9GTA9
names: Similarity
messages: Belongs to the 3-beta-HSD family.

29088:CHPF
gene id: 29088:CHPF
uniprot id: A0A2Y9I8C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

29088:BOLA1
gene id: 29088:BOLA1
uniprot id: A0A2Y9H130
names: Similarity
messages: Belongs to the BolA/IbaG family.

29088:TAF1D
gene id: 29088:TAF1D
uniprot id: A0A2Y9GAI5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B, TAF1C and TAF1D. Interacts with UBTF.
messages: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.
messages: Nucleus

29088:TBCA
gene id: 29088:TBCA
uniprot id: A0A2Y9I204
uniprot id: A0A8M1MJ58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
messages: cytoskeleton

29088:NR6A1
gene id: 29088:NR6A1
uniprot id: A0A8M1MYG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

29088:CALCRL
gene id: 29088:CALCRL
uniprot id: A0A2Y9I4B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3.
messages: Membrane
messages: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

29088:LOC110578761
gene id: 29088:LOC110578761
uniprot id: A0A2Y9GXS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIIb family.
messages: Membrane
messages: Mitochondrion inner membrane

29088:RNF5
gene id: 29088:RNF5
uniprot id: A0A2Y9HLU6
names: Domain
names: Function
names: Subcellular Location Annotation
messages: E3 ubiquitin-protein ligase.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion membrane
messages: The RING-type zinc finger domain is responsible for E3 ligase activity.

29088:IMPA1
gene id: 29088:IMPA1
uniprot id: A0A2Y9GXW3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

29088:SCG2
gene id: 29088:SCG2
uniprot id: A0A2Y9HIX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Interacts with Secretogranin III/SCG3.
messages: Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules.
messages: Secreted

29088:OVCH1
gene id: 29088:OVCH1
uniprot id: A0A8M1MBA1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:GABRD
gene id: 29088:GABRD
uniprot id: A0A2Y9GNY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:LOC110577409
gene id: 29088:LOC110577409
uniprot id: A0A2Y9GT76
names: Similarity
messages: Belongs to the intermediate filament family.

29088:XPNPEP1
gene id: 29088:XPNPEP1
uniprot id: A0A2Y9I118
uniprot id: A0A2Y9I2P9
uniprot id: A0A8M1MFD0
uniprot id: A0A8M1MIS7
uniprot id: A0A8M1MP31
names: Similarity
messages: Belongs to the peptidase M24B family.

29088:KHDC4
gene id: 29088:KHDC4
uniprot id: A0A2Y9GF00
uniprot id: A0A2Y9GF02
names: Similarity
messages: Belongs to the KHDC4 family.

29088:TUBB4B
gene id: 29088:TUBB4B
uniprot id: A0A2Y9HAA2
uniprot id: A0A8M1MRC5
uniprot id: A0A8M1MRD5
uniprot id: A0A8M1MUL3
uniprot id: A0A8M1MYH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

29088:HPRT1
gene id: 29088:HPRT1
uniprot id: A0A2Y9GLG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

29088:TBXA2R
gene id: 29088:TBXA2R
uniprot id: A0A2Y9IFA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:UPF3B
gene id: 29088:UPF3B
uniprot id: A0A2Y9GRK7
uniprot id: A0A2Y9GRN5
names: Similarity
messages: Belongs to the RENT3 family.

29088:NFIA
gene id: 29088:NFIA
uniprot id: A0A2Y9G9H6
uniprot id: A0A2Y9G9P4
uniprot id: A0A8M1MD26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

29088:CFAP300
gene id: 29088:CFAP300
uniprot id: A0A8M1MNB2
uniprot id: A0A8M1MRL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP300 family.
messages: Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. May play a role in outer and inner dynein arm assembly.
messages: Cytoplasm

29088:CLSTN2
gene id: 29088:CLSTN2
uniprot id: A0A8M1M322
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

29088:KIF26A
gene id: 29088:KIF26A
uniprot id: A0A8M1MJF5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:PRKCG
gene id: 29088:PRKCG
uniprot id: A0A8M1M7Y6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domain.
messages: Cytoplasm
messages: Membrane

29088:PDHA1
gene id: 29088:PDHA1
uniprot id: A0A2Y9GNX2
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

29088:TLX3
gene id: 29088:TLX3
uniprot id: A0A2Y9HX65
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110591634
gene id: 29088:LOC110591634
uniprot id: A0A8M1MLQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Membrane
messages: Mitochondrion inner membrane

29088:ITGA6
gene id: 29088:ITGA6
uniprot id: A0A2Y9IB82
uniprot id: A0A8M1M6W6
uniprot id: A0A8M1M764
uniprot id: A0A8M1MAQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

29088:GHITM
gene id: 29088:GHITM
uniprot id: A0A2Y9HW99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

29088:LOC110575264
gene id: 29088:LOC110575264
uniprot id: A0A2Y9GRK2
uniprot id: A0A8M1M988
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

29088:BNIP3L
gene id: 29088:BNIP3L
uniprot id: A0A2Y9HSI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

29088:MRPL2
gene id: 29088:MRPL2
uniprot id: A0A2Y9H7Q7
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

29088:NDUFS6
gene id: 29088:NDUFS6
uniprot id: A0A2Y9GYA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS6 subunit family.
messages: Mitochondrion inner membrane

29088:NRP2
gene id: 29088:NRP2
uniprot id: A0A2Y9I394
uniprot id: A0A2Y9I3I0
uniprot id: A0A2Y9I847
uniprot id: A0A8M1M9E2
uniprot id: A0A8M1MF87
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:B3GALT4
gene id: 29088:B3GALT4
uniprot id: A0A2Y9GM22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:TMEM263
gene id: 29088:TMEM263
uniprot id: A0A2Y9GVL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

29088:SEMA6D
gene id: 29088:SEMA6D
uniprot id: A0A8M1MSR9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:HIGD1B
gene id: 29088:HIGD1B
uniprot id: A0A2Y9GEE4
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

29088:PSMD1
gene id: 29088:PSMD1
uniprot id: A0A2Y9H9T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S1 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

29088:PIGL
gene id: 29088:PIGL
uniprot id: A0A2Y9HFL1
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

29088:LOC110587303
gene id: 29088:LOC110587303
uniprot id: A0A8M1MPP0
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

29088:LOC110575422
gene id: 29088:LOC110575422
uniprot id: A0A8M1M265
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

29088:AGBL3
gene id: 29088:AGBL3
uniprot id: A0A8M1MTG5
uniprot id: A0A8M1MY90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

29088:CSE1L
gene id: 29088:CSE1L
uniprot id: A0A2Y9GQV3
uniprot id: A0A8M1MM39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPO2/CSE1 family.
messages: Cytoplasm

29088:C1R
gene id: 29088:C1R
uniprot id: A0A8M1MC20
uniprot id: A0A8M1MC68
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:INKA2
gene id: 29088:INKA2
uniprot id: A0A2Y9H2T1
uniprot id: A0A2Y9H2W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

29088:PDE11A
gene id: 29088:PDE11A
uniprot id: A0A2Y9I425
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

29088:PDE9A
gene id: 29088:PDE9A
uniprot id: A0A8M1MQ98
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

29088:LOC110575802
gene id: 29088:LOC110575802
uniprot id: A0A2Y9GRQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:TFIP11
gene id: 29088:TFIP11
uniprot id: A0A2Y9I5W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFP11/STIP family.
messages: Identified in the spliceosome C complex. Found in the Intron Large (IL) complex, a post-mRNA release spliceosomal complex containing the excised intron, U2, U5 and U6 snRNPs, and splicing factors. Interacts with TUFT1. Interacts with DHX15; indicative for a recruitment of DHX15 to the IL complex. Interacts with GCFC2.
messages: Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix.
messages: Nucleus

29088:PHC1
gene id: 29088:PHC1
uniprot id: A0A2Y9H461
names: Subcellular Location Annotation
messages: Nucleus

29088:DEFB128
gene id: 29088:DEFB128
uniprot id: A0A2Y9H4N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

29088:LOC110583361
gene id: 29088:LOC110583361
uniprot id: A0A2Y9HBN0
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

29088:CTNS
gene id: 29088:CTNS
uniprot id: A0A2Y9I7P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cystinosin family.
messages: Membrane

29088:LOC110582808
gene id: 29088:LOC110582808
uniprot id: A0A2Y9H9T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SNX20
gene id: 29088:SNX20
uniprot id: A0A2Y9IDH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Membrane

29088:POU3F3
gene id: 29088:POU3F3
uniprot id: A0A8M1MM83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

29088:MEF2C
gene id: 29088:MEF2C
uniprot id: A0A2Y9HTJ5
uniprot id: A0A8M1MGG9
uniprot id: A0A8M1MGH0
uniprot id: A0A8M1MGH4
uniprot id: A0A8M1MGH6
uniprot id: A0A8M1MGH9
uniprot id: A0A8M1MGI1
uniprot id: A0A8M1MIK1
uniprot id: A0A8M1MIK6
uniprot id: A0A8M1MIL5
uniprot id: A0A8M1MJX0
uniprot id: A0A8M1MJX8
uniprot id: A0A8M1MQB1
uniprot id: A0A8M1MQB6
uniprot id: A0A8M1MQC5
names: Subcellular Location Annotation
messages: Nucleus

29088:TXNRD3
gene id: 29088:TXNRD3
uniprot id: A0A2Y9HG48
uniprot id: A0A2Y9HMG1
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

29088:MLF2
gene id: 29088:MLF2
uniprot id: A0A2Y9H9K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

29088:SRFBP1
gene id: 29088:SRFBP1
uniprot id: A0A2Y9I1B4
names: Function
names: Subunit
messages: Interacts with SRF. Forms complexes with SRF and SRF cofactors ARID2, MYOCD and NKX2-5. Interacts with the N-terminus of SLC2A4.
messages: May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells.

29088:GPC6
gene id: 29088:GPC6
uniprot id: A0A2Y9HIX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

29088:TTYH3
gene id: 29088:TTYH3
uniprot id: A0A2Y9GDS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

29088:SLC16A14
gene id: 29088:SLC16A14
uniprot id: A0A2Y9GMS2
names: Subcellular Location Annotation
messages: Membrane

29088:IFI30
gene id: 29088:IFI30
uniprot id: A0A2Y9GLE6
uniprot id: A0A8M1MRR7
names: Similarity
names: Subunit
messages: Belongs to the GILT family.
messages: Dimer; disulfide-linked.

29088:CLTCL1
gene id: 29088:CLTCL1
uniprot id: A0A2Y9H4J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: coated pit

29088:ALDOC
gene id: 29088:ALDOC
uniprot id: A0A8M1MWX2
uniprot id: A0A8M1MZA3
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

29088:LOC110575700
gene id: 29088:LOC110575700
uniprot id: A0A2Y9GMF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

29088:RNF111
gene id: 29088:RNF111
uniprot id: A0A2Y9HD08
uniprot id: A0A2Y9HJB4
uniprot id: A0A8M1MIT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Arkadia family.
messages: PML body

29088:ZSCAN10
gene id: 29088:ZSCAN10
uniprot id: A0A2Y9HQV2
names: Subcellular Location Annotation
messages: Nucleus

29088:UCN3
gene id: 29088:UCN3
uniprot id: A0A2Y9HLC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

29088:PLPP3
gene id: 29088:PLPP3
uniprot id: A0A2Y9GLM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

29088:DRD5
gene id: 29088:DRD5
uniprot id: A0A2Y9G665
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:CNOT9
gene id: 29088:CNOT9
uniprot id: A0A2Y9I3I2
uniprot id: A0A8M1M8J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT9 family.
messages: P-body

29088:MRPL10
gene id: 29088:MRPL10
uniprot id: A0A2Y9I8B2
uniprot id: A0A2Y9IEY0
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

29088:NOX5
gene id: 29088:NOX5
uniprot id: A0A8M1MNH6
names: Subcellular Location Annotation
messages: Membrane

29088:STARD5
gene id: 29088:STARD5
uniprot id: A0A2Y9GE81
names: Function
messages: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.

29088:GCH1
gene id: 29088:GCH1
uniprot id: A0A2Y9HZW5
uniprot id: A0A2Y9I6A3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

29088:PITPNM1
gene id: 29088:PITPNM1
uniprot id: A0A2Y9GNT1
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

29088:TEAD3
gene id: 29088:TEAD3
uniprot id: A0A2Y9GSW7
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

29088:ADAM22
gene id: 29088:ADAM22
uniprot id: A0A2Y9H0X5
uniprot id: A0A2Y9H128
uniprot id: A0A2Y9H133
uniprot id: A0A2Y9H138
uniprot id: A0A2Y9H5S0
uniprot id: A0A2Y9H7H6
uniprot id: A0A2Y9H7I0
uniprot id: A0A8M1MQP3
uniprot id: A0A8M1MQP9
uniprot id: A0A8M1MSK1
uniprot id: A0A8M1MSK6
uniprot id: A0A8M1MTY1
uniprot id: A0A8M1MYD1
uniprot id: A0A8M1MYD2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110591050
gene id: 29088:LOC110591050
uniprot id: A0A8M1MI72
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

29088:GBX1
gene id: 29088:GBX1
uniprot id: A0A2Y9HAA4
names: Subcellular Location Annotation
messages: Nucleus

29088:GPR52
gene id: 29088:GPR52
uniprot id: A0A2Y9GH88
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:EIF2B5
gene id: 29088:EIF2B5
uniprot id: A0A2Y9H8J2
uniprot id: A0A8M1MIA2
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

29088:TRAK1
gene id: 29088:TRAK1
uniprot id: A0A2Y9G6G0
uniprot id: A0A2Y9G6G2
uniprot id: A0A2Y9G6G5
uniprot id: A0A2Y9G6U6
uniprot id: A0A2Y9G8X0
uniprot id: A0A2Y9G8X5
uniprot id: A0A2Y9GA07
uniprot id: A0A8M1MRU7
uniprot id: A0A8M1MYL2
uniprot id: A0A8M1MYL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion

29088:MAP7D3
gene id: 29088:MAP7D3
uniprot id: A0A8M1M1V3
names: Similarity
messages: Belongs to the MAP7 family.

29088:HS6ST3
gene id: 29088:HS6ST3
uniprot id: A0A2Y9HPV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

29088:STN1
gene id: 29088:STN1
uniprot id: A0A2Y9HVA3
uniprot id: A0A2Y9HVU8
uniprot id: A0A2Y9HVV7
uniprot id: A0A2Y9I0L5
uniprot id: A0A2Y9I280
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the STN1 family.
messages: Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
messages: Component of the CST complex.
messages: Nucleus
messages: telomere

29088:FADS3
gene id: 29088:FADS3
uniprot id: A0A2Y9GMZ9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

29088:LOC110587742
gene id: 29088:LOC110587742
uniprot id: A0A8M1M5G0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

29088:LOC110579539
gene id: 29088:LOC110579539
uniprot id: A0A2Y9H034
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

29088:SPINK4
gene id: 29088:SPINK4
uniprot id: A0A2Y9H6Q3
names: Subcellular Location Annotation
messages: Secreted

29088:CALCR
gene id: 29088:CALCR
uniprot id: A0A2Y9H1N6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Interacts with GPRASP2.
messages: Membrane

29088:LOC110592411
gene id: 29088:LOC110592411
uniprot id: A0A2Y9I542
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCR10/QCR9 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

29088:SEPTIN2
gene id: 29088:SEPTIN2
uniprot id: A0A2Y9G6S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Filament-forming cytoskeletal GTPase.
messages: Midbody
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.
messages: cilium membrane
messages: flagellum
messages: spindle

29088:LOC110573916
gene id: 29088:LOC110573916
uniprot id: A0A8M1MFJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

29088:FERMT1
gene id: 29088:FERMT1
uniprot id: A0A2Y9H005
uniprot id: A0A2Y9H6D7
uniprot id: A0A8M1MVB5
names: Similarity
messages: Belongs to the kindlin family.

29088:AGAP1
gene id: 29088:AGAP1
uniprot id: A0A2Y9G6R0
uniprot id: A0A8M1MFG9
names: Similarity
messages: Belongs to the centaurin gamma-like family.

29088:ATOH7
gene id: 29088:ATOH7
uniprot id: A0A2Y9HVX5
names: Subcellular Location Annotation
messages: Nucleus
messages: Perikaryon
messages: axon

29088:LOC110573080
gene id: 29088:LOC110573080
uniprot id: A0A2Y9GGS2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

29088:CDCA5
gene id: 29088:CDCA5
uniprot id: A0A2Y9GNA8
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

29088:SLC6A17
gene id: 29088:SLC6A17
uniprot id: A0A2Y9H2K1
uniprot id: A0A2Y9H970
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

29088:CACNA1G
gene id: 29088:CACNA1G
uniprot id: A0A2Y9I6H5
uniprot id: A0A2Y9I6I1
uniprot id: A0A2Y9I6I7
uniprot id: A0A2Y9I6J2
uniprot id: A0A2Y9I6K3
uniprot id: A0A2Y9I6W7
uniprot id: A0A2Y9I6X2
uniprot id: A0A2Y9I6X8
uniprot id: A0A2Y9I6Y3
uniprot id: A0A2Y9I7B5
uniprot id: A0A2Y9I7B8
uniprot id: A0A2Y9I7C2
uniprot id: A0A2Y9I7D2
uniprot id: A0A2Y9IBC6
uniprot id: A0A2Y9IBD1
uniprot id: A0A2Y9IDY3
uniprot id: A0A2Y9IDY8
uniprot id: A0A2Y9IDZ3
uniprot id: A0A2Y9IDZ9
uniprot id: A0A2Y9IE04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.

29088:SEC61B
gene id: 29088:SEC61B
uniprot id: A0A2Y9HAM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Necessary for protein translocation in the endoplasmic reticulum.

29088:LTB4R2
gene id: 29088:LTB4R2
uniprot id: A0A2Y9HNP8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:SPRN
gene id: 29088:SPRN
uniprot id: A0A8M1MHI7
names: Function
names: Similarity
messages: Belongs to the SPRN family.
messages: Prion-like protein that has PrP(C)-like neuroprotective activity. May act as a modulator for the biological actions of normal and abnormal PrP.

29088:ADIPOR2
gene id: 29088:ADIPOR2
uniprot id: A0A2Y9H4B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

29088:POLR3K
gene id: 29088:POLR3K
uniprot id: A0A2Y9HQ60
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: nucleolus

29088:CARMIL1
gene id: 29088:CARMIL1
uniprot id: A0A2Y9HRZ1
uniprot id: A0A8M1MJA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

29088:LOC110586429
gene id: 29088:LOC110586429
uniprot id: A0A2Y9HKX0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110587131
gene id: 29088:LOC110587131
uniprot id: A0A2Y9HT10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

29088:KCNK2
gene id: 29088:KCNK2
uniprot id: A0A2Y9GGG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

29088:HS3ST4
gene id: 29088:HS3ST4
uniprot id: A0A2Y9I3V2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

29088:LOC110576465
gene id: 29088:LOC110576465
uniprot id: A0A2Y9GQ36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SCARF2
gene id: 29088:SCARF2
uniprot id: A0A2Y9GWH0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:DXO
gene id: 29088:DXO
uniprot id: A0A2Y9HS29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Binds 2 magnesium ions.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

29088:NMNAT2
gene id: 29088:NMNAT2
uniprot id: A0A2Y9GH28
uniprot id: A0A2Y9GH60
uniprot id: A0A2Y9GKE3
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

29088:ORC2
gene id: 29088:ORC2
uniprot id: A0A2Y9I4E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC2 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Component of the origin recognition complex (ORC).
messages: Nucleus

29088:DEFB134
gene id: 29088:DEFB134
uniprot id: A0A2Y9HXT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

29088:CARTPT
gene id: 29088:CARTPT
uniprot id: A0A2Y9HWS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

29088:RPS14
gene id: 29088:RPS14
uniprot id: A0A2Y9HM51
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

29088:CDH15
gene id: 29088:CDH15
uniprot id: A0A2Y9I6Y4
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

29088:LOC110576050
gene id: 29088:LOC110576050
uniprot id: A0A2Y9GNH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GST superfamily. Pi family.
messages: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
messages: Cytoplasm
messages: Homodimer.
messages: Mitochondrion
messages: Nucleus

29088:LOC110583667
gene id: 29088:LOC110583667
uniprot id: A0A8M1MLR4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with chaperones HSP70 and HSP90; this interaction is required for initial targeting to mitochondria.
messages: Membrane
messages: Microsome membrane
messages: Mitochondrion inner membrane
messages: The omega-1 hydroxylase activity is stimulated by cytochrome b5.

29088:PACS1
gene id: 29088:PACS1
uniprot id: A0A8M1MMX7
uniprot id: A0A8M1MR90
names: Similarity
messages: Belongs to the PACS family.

29088:LOC110575855
gene id: 29088:LOC110575855
uniprot id: A0A2Y9GN38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SLC17A8
gene id: 29088:SLC17A8
uniprot id: A0A2Y9GZL1
names: Subcellular Location Annotation
messages: Membrane

29088:HUS1
gene id: 29088:HUS1
uniprot id: A0A8M1MY99
names: Similarity
messages: Belongs to the HUS1 family.

29088:LOC123325526
gene id: 29088:LOC123325526
uniprot id: A0A2Y9GUW2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:LOC110574335
gene id: 29088:LOC110574335
uniprot id: A0A2Y9GHP5
names: Similarity
messages: Belongs to the AKAP110 family.

29088:LOC110575040
gene id: 29088:LOC110575040
uniprot id: A0A8M1M859
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

29088:INSM2
gene id: 29088:INSM2
uniprot id: A0A2Y9GC11
names: Subcellular Location Annotation
messages: Nucleus

29088:IFI35
gene id: 29088:IFI35
uniprot id: A0A8M1MWK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NMI family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

29088:CNIH4
gene id: 29088:CNIH4
uniprot id: A0A2Y9GBI2
uniprot id: A0A8M1MID4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

29088:KCNH5
gene id: 29088:KCNH5
uniprot id: A0A2Y9I6E5
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110582490
gene id: 29088:LOC110582490
uniprot id: A0A2Y9HFT3
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

29088:IPO9
gene id: 29088:IPO9
uniprot id: A0A2Y9GH06
names: Subcellular Location Annotation
messages: Cytoplasm

29088:LOC110575783
gene id: 29088:LOC110575783
uniprot id: A0A2Y9GMK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:MRPS30
gene id: 29088:MRPS30
uniprot id: A0A2Y9HL75
names: Subcellular Location Annotation
messages: Mitochondrion

29088:LOC110585310
gene id: 29088:LOC110585310
uniprot id: A0A2Y9HHE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ZBED1
gene id: 29088:ZBED1
uniprot id: A0A2Y9H074
names: Subcellular Location Annotation
messages: Nucleus

29088:GADD45A
gene id: 29088:GADD45A
uniprot id: A0A2Y9G9G9
uniprot id: A0A8M1MBR8
names: Similarity
messages: Belongs to the GADD45 family.

29088:DEFB106B
gene id: 29088:DEFB106B
uniprot id: A0A2Y9HE76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

29088:ITPR2
gene id: 29088:ITPR2
uniprot id: A0A8M1MFM1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

29088:PARL
gene id: 29088:PARL
uniprot id: A0A2Y9HFA2
uniprot id: A0A8M1MA32
uniprot id: A0A8M1MC72
uniprot id: A0A8M1MDK9
names: Subcellular Location Annotation
messages: Membrane

29088:SKIV2L
gene id: 29088:SKIV2L
uniprot id: A0A2Y9HLS8
names: Subcellular Location Annotation
messages: Cytoplasm

29088:DPH2
gene id: 29088:DPH2
uniprot id: A0A2Y9GK73
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.

29088:TDRD3
gene id: 29088:TDRD3
uniprot id: A0A2Y9HPK1
uniprot id: A0A2Y9HPQ5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:LOC110581675
gene id: 29088:LOC110581675
uniprot id: A0A2Y9HBZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:C3
gene id: 29088:C3
uniprot id: A0A2Y9IBQ0
names: Function
names: Subcellular Location Annotation
messages: Acts as a chemoattractant for neutrophils in chronic inflammation.
messages: C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.
messages: Secreted

29088:LOC110588796
gene id: 29088:LOC110588796
uniprot id: A0A2Y9HSX8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

29088:SLC25A41
gene id: 29088:SLC25A41
uniprot id: A0A2Y9IHX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:FMO2
gene id: 29088:FMO2
uniprot id: A0A2Y9GLQ8
uniprot id: A0A8M1MEQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

29088:USH2A
gene id: 29088:USH2A
uniprot id: A0A2Y9HQT6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:SLC28A3
gene id: 29088:SLC28A3
uniprot id: A0A2Y9G623
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

29088:CLUH
gene id: 29088:CLUH
uniprot id: A0A2Y9I744
uniprot id: A0A2Y9I7F0
uniprot id: A0A2Y9IBV2
uniprot id: A0A2Y9IEJ8
uniprot id: A0A8M1MUI4
uniprot id: A0A8M1MUI5
uniprot id: A0A8M1MWB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLU family.
messages: Cytoplasm
messages: Cytoplasmic granule
messages: mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis.

29088:C11H11orf87
gene id: 29088:C11H11orf87
uniprot id: A0A8M1MQV1
names: Subcellular Location Annotation
messages: Membrane

29088:HOXC11
gene id: 29088:HOXC11
uniprot id: A0A2Y9GT22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

29088:NDUFB2
gene id: 29088:NDUFB2
uniprot id: A0A2Y9HA44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:CHCHD6
gene id: 29088:CHCHD6
uniprot id: A0A2Y9HMI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MICOS complex subunit Mic19 family. Metazoan Mic25 subfamily.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Membrane
messages: Mitochondrion inner membrane

29088:LOC110576868
gene id: 29088:LOC110576868
uniprot id: A0A2Y9GJP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM3 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.

29088:NPBWR1
gene id: 29088:NPBWR1
uniprot id: A0A2Y9GYL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:TMEM63A
gene id: 29088:TMEM63A
uniprot id: A0A2Y9G8C3
uniprot id: A0A2Y9GAP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

29088:LOC110577980
gene id: 29088:LOC110577980
uniprot id: A0A2Y9H169
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCO1/2 family.
messages: Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2.
messages: Homodimer.
messages: Mitochondrion inner membrane

29088:YBEY
gene id: 29088:YBEY
uniprot id: A0A2Y9G6Z1
uniprot id: A0A8M1M5L1
names: Similarity
messages: Belongs to the endoribonuclease YbeY family.

29088:LIPH
gene id: 29088:LIPH
uniprot id: A0A2Y9H918
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

29088:LOC110582944
gene id: 29088:LOC110582944
uniprot id: A0A2Y9HH08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL18 family.
messages: Rough endoplasmic reticulum

29088:NQO1
gene id: 29088:NQO1
uniprot id: A0A2Y9IBM3
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

29088:DNAH14
gene id: 29088:DNAH14
uniprot id: A0A8M1MHQ1
names: Similarity
messages: Belongs to the dynein heavy chain family.

29088:TMEM53
gene id: 29088:TMEM53
uniprot id: A0A2Y9GNM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM53 family.
messages: Membrane
messages: Nucleus outer membrane

29088:LOC110593941
gene id: 29088:LOC110593941
uniprot id: A0A2Y9IBH9
uniprot id: A0A2Y9II69
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with EIF4G1. Associates with ribosomes.
messages: nucleoplasm

29088:ERAP1
gene id: 29088:ERAP1
uniprot id: A0A2Y9I721
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

29088:LCTL
gene id: 29088:LCTL
uniprot id: A0A2Y9HJP6
uniprot id: A0A8M1MLR5
uniprot id: A0A8M1MTS1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

29088:E2F6
gene id: 29088:E2F6
uniprot id: A0A2Y9HMZ7
uniprot id: A0A2Y9HTE9
uniprot id: A0A2Y9HUU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

29088:ACAP3
gene id: 29088:ACAP3
uniprot id: A0A2Y9GIM1
uniprot id: A0A2Y9GM19
uniprot id: A0A2Y9GNW1
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

29088:HSPH1
gene id: 29088:HSPH1
uniprot id: A0A2Y9G4H6
uniprot id: A0A2Y9G4J9
uniprot id: A0A8M1M5U9
uniprot id: A0A8M1M9F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm

29088:C1H19orf25
gene id: 29088:C1H19orf25
uniprot id: A0A2Y9IAQ4
uniprot id: A0A2Y9IHY9
names: Similarity
messages: Belongs to the UPF0449 family.

29088:CUL5
gene id: 29088:CUL5
uniprot id: A0A2Y9HKL3
names: Similarity
messages: Belongs to the cullin family.

29088:ALPL
gene id: 29088:ALPL
uniprot id: A0A2Y9GMR4
uniprot id: A0A2Y9GPF2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

29088:PPIL6
gene id: 29088:PPIL6
uniprot id: A0A2Y9HGT3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

29088:LOC110569960
gene id: 29088:LOC110569960
uniprot id: A0A2Y9G3J8
names: Similarity
messages: Belongs to the SPATA31 family.

29088:LDB3
gene id: 29088:LDB3
uniprot id: A0A8M1MH69
names: Subcellular Location Annotation
messages: Z line

29088:GLIS3
gene id: 29088:GLIS3
uniprot id: A0A2Y9HE94
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

29088:PCSK7
gene id: 29088:PCSK7
uniprot id: A0A2Y9HRX1
names: Similarity
messages: Belongs to the peptidase S8 family.

29088:AADACL2
gene id: 29088:AADACL2
uniprot id: A0A2Y9GR31
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

29088:LOC110589764
gene id: 29088:LOC110589764
uniprot id: A0A8M1MGB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

29088:EMP1
gene id: 29088:EMP1
uniprot id: A0A2Y9H3X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

29088:SLC33A1
gene id: 29088:SLC33A1
uniprot id: A0A2Y9I373
uniprot id: A0A8M1MJI7
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110569635
gene id: 29088:LOC110569635
uniprot id: A0A8M1M1F9
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

29088:LOC110576132
gene id: 29088:LOC110576132
uniprot id: A0A2Y9GUG2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SLC8A3
gene id: 29088:SLC8A3
uniprot id: A0A2Y9G836
uniprot id: A0A2Y9G8A6
uniprot id: A0A2Y9G8F2
uniprot id: A0A2Y9GAS6
uniprot id: A0A2Y9GBR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

29088:TNFRSF4
gene id: 29088:TNFRSF4
uniprot id: A0A2Y9GRU0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:SRXN1
gene id: 29088:SRXN1
uniprot id: A0A2Y9GZT6
names: Similarity
messages: Belongs to the sulfiredoxin family.

29088:SMIM14
gene id: 29088:SMIM14
uniprot id: A0A2Y9I093
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

29088:LOC110590615
gene id: 29088:LOC110590615
uniprot id: A0A8M1ML78
names: Function
names: Similarity
messages: Belongs to the cyclin family.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.

29088:LOC110571144
gene id: 29088:LOC110571144
uniprot id: A0A2Y9HUR8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

29088:LOC110593898
gene id: 29088:LOC110593898
uniprot id: A0A8M1MVW9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPRTase family.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Secreted

29088:LOC110586320
gene id: 29088:LOC110586320
uniprot id: A0A2Y9HKM0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:HOXC6
gene id: 29088:HOXC6
uniprot id: A0A2Y9GT28
uniprot id: A0A8M1MDW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

29088:IL33
gene id: 29088:IL33
uniprot id: A0A2Y9GG18
uniprot id: A0A8M1MTM2
uniprot id: A0A8M1MUZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family. Highly divergent.
messages: Chromosome
messages: Nucleus
messages: Secreted
messages: Vesicle
messages: secretory vesicle

29088:ZMYND10
gene id: 29088:ZMYND10
uniprot id: A0A2Y9GZP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the ZMYND10 family.
messages: Dynein axonemal particle
messages: Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins.
messages: centriolar satellite

29088:VPS37D
gene id: 29088:VPS37D
uniprot id: A0A2Y9HXI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

29088:SNX11
gene id: 29088:SNX11
uniprot id: A0A2Y9I7N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

29088:LOC110582985
gene id: 29088:LOC110582985
uniprot id: A0A8M1M1E4
names: Similarity
messages: Belongs to the SCC3 family.

29088:HMCES
gene id: 29088:HMCES
uniprot id: A0A2Y9HG72
uniprot id: A0A8M1MGE5
uniprot id: A0A8M1MHT4
names: Function
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.
messages: Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA: forms a stable thiazolidine linkage between a ring-opened abasic site and the alpha-amino and sulfhydryl substituents of its N-terminal catalytic cysteine residue. The HMCES DNA-protein cross-link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endonucleases that are error-prone and would generate mutations and double-strand breaks. Has preference for ssDNA, but can also accommodate double-stranded DNA with 3' or 5' overhang (dsDNA), and dsDNA-ssDNA 3' junction.

29088:CMC2
gene id: 29088:CMC2
uniprot id: A0A2Y9I349
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

29088:HSP90AA1
gene id: 29088:HSP90AA1
uniprot id: A0A2Y9G9A5
uniprot id: A0A8M1MMM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 90 family.
messages: Melanosome

29088:AKAP3
gene id: 29088:AKAP3
uniprot id: A0A2Y9H983
names: Similarity
messages: Belongs to the AKAP110 family.

29088:ITIH2
gene id: 29088:ITIH2
uniprot id: A0A2Y9HSL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

29088:RAD51D
gene id: 29088:RAD51D
uniprot id: A0A2Y9I756
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus

29088:ADORA2A
gene id: 29088:ADORA2A
uniprot id: A0A2Y9GW70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

29088:DHRS3
gene id: 29088:DHRS3
uniprot id: A0A2Y9GP82
uniprot id: A0A8M1M7H3
uniprot id: A0A8M1M7R3
uniprot id: A0A8M1M9W8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29088:IL2RA
gene id: 29088:IL2RA
uniprot id: A0A8M1MF21
names: Caution
names: Function
names: Subunit
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.
messages: Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.

29088:RGS12
gene id: 29088:RGS12
uniprot id: A0A2Y9G3D3
uniprot id: A0A8M1M7G9
names: Subcellular Location Annotation
messages: Cytoplasm

29088:COPS6
gene id: 29088:COPS6
uniprot id: A0A2Y9GCH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN6 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.
messages: Cytoplasm
messages: Nucleus

29088:GFM2
gene id: 29088:GFM2
uniprot id: A0A2Y9I1D4
uniprot id: A0A2Y9I1K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
messages: Mitochondrion

29088:SLC6A16
gene id: 29088:SLC6A16
uniprot id: A0A2Y9GCP7
names: Subcellular Location Annotation
messages: Membrane

29088:CS
gene id: 29088:CS
uniprot id: A0A2Y9GU88
uniprot id: A0A2Y9GU92
uniprot id: A0A2Y9GUE8
uniprot id: A0A2Y9H073
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the citrate synthase family.
messages: Homodimer.
messages: Mitochondrion matrix

29088:BIRC3
gene id: 29088:BIRC3
uniprot id: A0A2Y9HKE6
uniprot id: A0A2Y9HKP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IAP family.
messages: Cytoplasm
messages: Nucleus

29088:GGA3
gene id: 29088:GGA3
uniprot id: A0A2Y9GCA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

29088:FGR
gene id: 29088:FGR
uniprot id: A0A2Y9GMY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

29088:LOC110585376
gene id: 29088:LOC110585376
uniprot id: A0A8M1MTW0
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

29088:NPR2
gene id: 29088:NPR2
uniprot id: A0A2Y9HCK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

29088:POLH
gene id: 29088:POLH
uniprot id: A0A2Y9H7L9
uniprot id: A0A2Y9H7M7
uniprot id: A0A2Y9HEH3
names: Subcellular Location Annotation
messages: Nucleus

29088:SLC25A51
gene id: 29088:SLC25A51
uniprot id: A0A2Y9HD43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:CISD2
gene id: 29088:CISD2
uniprot id: A0A2Y9GAS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CISD protein family. CISD2 subfamily.
messages: Binds 1 [2Fe-2S] cluster.
messages: Endoplasmic reticulum membrane
messages: Homodimer.
messages: Mitochondrion outer membrane
messages: Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy.

29088:FIGNL1
gene id: 29088:FIGNL1
uniprot id: A0A2Y9I5W1
names: Similarity
messages: Belongs to the AAA ATPase family.

29088:ZPBP2
gene id: 29088:ZPBP2
uniprot id: A0A8M1MV82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zona pellucida-binding protein Sp38 family.
messages: Secreted
messages: acrosome

29088:CHGB
gene id: 29088:CHGB
uniprot id: A0A2Y9H482
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

29088:ETFB
gene id: 29088:ETFB
uniprot id: A0A2Y9GDJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

29088:LOC110575893
gene id: 29088:LOC110575893
uniprot id: A0A2Y9GN81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INCENP family.
messages: Midbody
messages: Nucleus
messages: kinetochore
messages: spindle

29088:WEE2
gene id: 29088:WEE2
uniprot id: A0A8M1MQG2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

29088:SLC30A5
gene id: 29088:SLC30A5
uniprot id: A0A2Y9HWW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Membrane
messages: trans-Golgi network membrane

29088:ANP32A
gene id: 29088:ANP32A
uniprot id: A0A2Y9HCG0
uniprot id: A0A2Y9HCL3
uniprot id: A0A2Y9HCS9
uniprot id: A0A8M1MM57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANP32 family.
messages: Multifunctional protein that is involved in the regulation of many processes.
messages: Nucleus

29088:SPI1
gene id: 29088:SPI1
uniprot id: A0A2Y9GMJ5
uniprot id: A0A2Y9GTA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

29088:P4HA1
gene id: 29088:P4HA1
uniprot id: A0A2Y9HVV9
uniprot id: A0A2Y9HWG0
uniprot id: A0A2Y9I142
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

29088:HMGB3
gene id: 29088:HMGB3
uniprot id: A0A2Y9GIW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

29088:DNAJC10
gene id: 29088:DNAJC10
uniprot id: A0A2Y9I4U2
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.
messages: Endoplasmic reticulum lumen

29088:UGP2
gene id: 29088:UGP2
uniprot id: A0A2Y9HTA4
uniprot id: A0A2Y9HTA9
uniprot id: A0A2Y9HTC5
uniprot id: A0A2Y9HZR1
uniprot id: A0A8M1MPS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

29088:MTFR1
gene id: 29088:MTFR1
uniprot id: A0A2Y9H3I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

29088:MDFI
gene id: 29088:MDFI
uniprot id: A0A2Y9H7Z9
names: Similarity
messages: Belongs to the MDFI family.

29088:HDAC6
gene id: 29088:HDAC6
uniprot id: A0A2Y9G6D7
uniprot id: A0A2Y9G6S6
names: Similarity
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.

29088:LOC110574607
gene id: 29088:LOC110574607
uniprot id: A0A8M1MB74
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

29088:AFM
gene id: 29088:AFM
uniprot id: A0A2Y9I257
names: Subcellular Location Annotation
messages: Secreted

29088:LOC110581521
gene id: 29088:LOC110581521
uniprot id: A0A8M1M1K9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

29088:LOC110573247
gene id: 29088:LOC110573247
uniprot id: A0A2Y9GEA3
names: Similarity
messages: Belongs to the intermediate filament family.

29088:IGFBP5
gene id: 29088:IGFBP5
uniprot id: A0A2Y9I479
names: Caution
names: Function
names: Subcellular Location Annotation
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:LOC110591759
gene id: 29088:LOC110591759
uniprot id: A0A2Y9I7W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

29088:ABL1
gene id: 29088:ABL1
uniprot id: A0A2Y9H5N5
uniprot id: A0A2Y9H5R0
uniprot id: A0A8M1MRG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

29088:TNFRSF11B
gene id: 29088:TNFRSF11B
uniprot id: A0A2Y9GXX3
names: Caution
names: Function
names: Subunit
messages: Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110575799
gene id: 29088:LOC110575799
uniprot id: A0A2Y9GMZ5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:MEF2B
gene id: 29088:MEF2B
uniprot id: A0A2Y9GN47
names: Subcellular Location Annotation
messages: Nucleus

29088:SMAD6
gene id: 29088:SMAD6
uniprot id: A0A2Y9HJN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

29088:SVOPL
gene id: 29088:SVOPL
uniprot id: A0A8M1MY74
names: Subcellular Location Annotation
messages: Membrane

29088:BMP3
gene id: 29088:BMP3
uniprot id: A0A2Y9I2C3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer.
messages: Secreted

29088:LOC110581327
gene id: 29088:LOC110581327
uniprot id: A0A8M1MVL3
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

29088:NR1H2
gene id: 29088:NR1H2
uniprot id: A0A2Y9GDG1
uniprot id: A0A2Y9GDI2
uniprot id: A0A2Y9GGE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

29088:MMP8
gene id: 29088:MMP8
uniprot id: A0A2Y9HK46
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

29088:FAM163B
gene id: 29088:FAM163B
uniprot id: A0A2Y9H6R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

29088:STX11
gene id: 29088:STX11
uniprot id: A0A2Y9HBE8
names: Similarity
messages: Belongs to the syntaxin family.

29088:HENMT1
gene id: 29088:HENMT1
uniprot id: A0A8M1M8S4
names: Similarity
messages: Belongs to the methyltransferase superfamily. HEN1 family.

29088:SLC10A5
gene id: 29088:SLC10A5
uniprot id: A0A2Y9H464
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

29088:OAZ2
gene id: 29088:OAZ2
uniprot id: A0A8M1MU77
names: Similarity
messages: Belongs to the ODC antizyme family.

29088:FMO4
gene id: 29088:FMO4
uniprot id: A0A2Y9GGR0
uniprot id: A0A2Y9GGS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane

29088:AFF3
gene id: 29088:AFF3
uniprot id: A0A8M1MP74
names: Similarity
messages: Belongs to the AF4 family.

29088:NINJ1
gene id: 29088:NINJ1
uniprot id: A0A2Y9HKI9
uniprot id: A0A2Y9HKQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

29088:SUV39H2
gene id: 29088:SUV39H2
uniprot id: A0A2Y9HSQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
messages: Nucleus
messages: centromere

29088:PHF19
gene id: 29088:PHF19
uniprot id: A0A2Y9H5G0
uniprot id: A0A2Y9HC60
uniprot id: A0A8M1MSY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

29088:PSAT1
gene id: 29088:PSAT1
uniprot id: A0A2Y9H0J6
uniprot id: A0A2Y9H6Y5
uniprot id: A0A8M1MU61
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.

29088:LOC110570571
gene id: 29088:LOC110570571
uniprot id: A0A8M1MFF7
names: Subcellular Location Annotation
messages: Nucleus

29088:ERFL
gene id: 29088:ERFL
uniprot id: A0A8M1M875
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

29088:WRN
gene id: 29088:WRN
uniprot id: A0A2Y9HJP4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

29088:GPAT3
gene id: 29088:GPAT3
uniprot id: A0A2Y9I1S7
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

29088:STX12
gene id: 29088:STX12
uniprot id: A0A2Y9GJE0
names: Similarity
messages: Belongs to the syntaxin family.

29088:ZFP36L2
gene id: 29088:ZFP36L2
uniprot id: A0A2Y9HZ35
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

29088:LOC110572128
gene id: 29088:LOC110572128
uniprot id: A0A8M1M505
names: Similarity
messages: Belongs to the TMA7 family.

29088:SMOC2
gene id: 29088:SMOC2
uniprot id: A0A2Y9HB34
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ERBB3
gene id: 29088:ERBB3
uniprot id: A0A2Y9GYH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

29088:ATP1B2
gene id: 29088:ATP1B2
uniprot id: A0A2Y9HLQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

29088:LDAH
gene id: 29088:LDAH
uniprot id: A0A2Y9HNG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

29088:SYCP2L
gene id: 29088:SYCP2L
uniprot id: A0A2Y9HMI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYCP2 family.
messages: Nucleus

29088:LOC110573312
gene id: 29088:LOC110573312
uniprot id: A0A8M1MVH2
uniprot id: A0A8M1MX19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

29088:LOC110593627
gene id: 29088:LOC110593627
uniprot id: A0A2Y9IA20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:GORASP2
gene id: 29088:GORASP2
uniprot id: A0A2Y9I9I8
names: Similarity
messages: Belongs to the GORASP family.

29088:NCDN
gene id: 29088:NCDN
uniprot id: A0A2Y9GJL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurochondrin family.
messages: Postsynapse

29088:LOC110574472
gene id: 29088:LOC110574472
uniprot id: A0A2Y9GI64
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:KRT35
gene id: 29088:KRT35
uniprot id: A0A2Y9GHC5
names: Similarity
messages: Belongs to the intermediate filament family.

29088:LOC110573668
gene id: 29088:LOC110573668
uniprot id: A0A2Y9GFP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110584812
gene id: 29088:LOC110584812
uniprot id: A0A8M1MF80
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

29088:MEGF11
gene id: 29088:MEGF11
uniprot id: A0A2Y9HJ91
uniprot id: A0A8M1ML83
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:TXK
gene id: 29088:TXK
uniprot id: A0A2Y9I534
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

29088:VSX1
gene id: 29088:VSX1
uniprot id: A0A2Y9HXK8
names: Subcellular Location Annotation
messages: Nucleus

29088:ABCD4
gene id: 29088:ABCD4
uniprot id: A0A2Y9G9C9
uniprot id: A0A8M1MKM3
names: Subcellular Location Annotation
messages: Membrane

29088:CHMP5
gene id: 29088:CHMP5
uniprot id: A0A2Y9H6Q4
names: Similarity
messages: Belongs to the SNF7 family.

29088:STK32C
gene id: 29088:STK32C
uniprot id: A0A2Y9IAZ0
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:WNT2B
gene id: 29088:WNT2B
uniprot id: A0A2Y9H7B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

29088:COPZ1
gene id: 29088:COPZ1
uniprot id: A0A2Y9GSW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

29088:ACO2
gene id: 29088:ACO2
uniprot id: A0A2Y9H108
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Mitochondrion

29088:NPTX1
gene id: 29088:NPTX1
uniprot id: A0A8M1MUY1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110590481
gene id: 29088:LOC110590481
uniprot id: A0A8M1MM02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Monomer. Interacts with FAM72A.
messages: Nucleus

29088:LANCL2
gene id: 29088:LANCL2
uniprot id: A0A2Y9ID97
names: Similarity
messages: Belongs to the LanC-like protein family.

29088:DPEP3
gene id: 29088:DPEP3
uniprot id: A0A2Y9IBG7
names: Subcellular Location Annotation
messages: Membrane

29088:COL4A3
gene id: 29088:COL4A3
uniprot id: A0A2Y9GHL1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

29088:CXCL8
gene id: 29088:CXCL8
uniprot id: A0A2Y9I6R5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Homodimer.
messages: Secreted

29088:NELL1
gene id: 29088:NELL1
uniprot id: A0A2Y9GQG9
uniprot id: A0A2Y9GQQ7
uniprot id: A0A2Y9GW90
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:TES
gene id: 29088:TES
uniprot id: A0A2Y9HU59
uniprot id: A0A2Y9I0J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prickle / espinas / testin family.
messages: Cytoplasm
messages: Interacts via LIM domain 1 with ZYX. Interacts (via LIM domain 3) with ENAH and VASP. Interacts with ALKBH4, talin, actin, alpha-actinin, GRIP1 and PXN (By similarity). Interacts (via LIM domain 2) with ACTL7A (via N-terminus). Heterodimer with ACTL7A; the heterodimer interacts with ENAH to form a heterotrimer.
messages: Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor.
messages: focal adhesion

29088:SOD3
gene id: 29088:SOD3
uniprot id: A0A2Y9G7Q7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

29088:LOC110589063
gene id: 29088:LOC110589063
uniprot id: A0A8M1MHU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eS7 family.
messages: centrosome

29088:LTBR
gene id: 29088:LTBR
uniprot id: A0A2Y9H4C1
uniprot id: A0A8M1MKN0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:VPS33B
gene id: 29088:VPS33B
uniprot id: A0A2Y9GFB8
uniprot id: A0A8M1MNT3
uniprot id: A0A8M1MUK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: clathrin-coated vesicle

29088:BEST2
gene id: 29088:BEST2
uniprot id: A0A2Y9IBH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.
messages: Cell membrane
messages: Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
messages: Membrane

29088:CCNF
gene id: 29088:CCNF
uniprot id: A0A2Y9HQL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family.
messages: Nucleus
messages: centriole
messages: perinuclear region

29088:SLC44A3
gene id: 29088:SLC44A3
uniprot id: A0A2Y9H2B0
uniprot id: A0A8M1MAG1
uniprot id: A0A8M1MBU2
uniprot id: A0A8M1MGD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

29088:CSNK1G3
gene id: 29088:CSNK1G3
uniprot id: A0A2Y9I1Y2
uniprot id: A0A2Y9I267
uniprot id: A0A2Y9I6K7
uniprot id: A0A2Y9I8P5
uniprot id: A0A8M1MK90
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

29088:NLRP14
gene id: 29088:NLRP14
uniprot id: A0A2Y9GPU9
names: Similarity
messages: Belongs to the NLRP family.

29088:DTWD2
gene id: 29088:DTWD2
uniprot id: A0A2Y9I1H7
names: Similarity
messages: Belongs to the TDD superfamily. DTWD2 family.

29088:NFS1
gene id: 29088:NFS1
uniprot id: A0A2Y9GZD5
uniprot id: A0A8M1MKZ3
uniprot id: A0A8M1MMZ4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

29088:MFSD10
gene id: 29088:MFSD10
uniprot id: A0A2Y9G2J7
uniprot id: A0A2Y9G2K6
uniprot id: A0A2Y9G2Q2
uniprot id: A0A2Y9G360
uniprot id: A0A2Y9G574
uniprot id: A0A2Y9G6B2
names: Subcellular Location Annotation
messages: Membrane

29088:CACNB2
gene id: 29088:CACNB2
uniprot id: A0A2Y9HL66
uniprot id: A0A2Y9HL98
uniprot id: A0A2Y9HLD8
uniprot id: A0A2Y9HRT5
uniprot id: A0A2Y9HSU6
uniprot id: A0A2Y9HSV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: sarcolemma

29088:HCN3
gene id: 29088:HCN3
uniprot id: A0A2Y9GJM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

29088:LOC110588560
gene id: 29088:LOC110588560
uniprot id: A0A8M1MBS8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

29088:LOC110594282
gene id: 29088:LOC110594282
uniprot id: A0A8M1M1W6
names: Similarity
messages: Belongs to the SUI1 family.

29088:POU4F3
gene id: 29088:POU4F3
uniprot id: A0A2Y9I1F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

29088:PTPRF
gene id: 29088:PTPRF
uniprot id: A0A2Y9GL28
uniprot id: A0A2Y9GL73
uniprot id: A0A2Y9GLD9
uniprot id: A0A2Y9GPZ9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

29088:ATP6V1H
gene id: 29088:ATP6V1H
uniprot id: A0A2Y9GX72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

29088:DGKE
gene id: 29088:DGKE
uniprot id: A0A2Y9I8F3
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

29088:USP15
gene id: 29088:USP15
uniprot id: A0A2Y9G5R4
uniprot id: A0A2Y9G5R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Nucleus

29088:AVPR1A
gene id: 29088:AVPR1A
uniprot id: A0A2Y9G605
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.

29088:PAXBP1
gene id: 29088:PAXBP1
uniprot id: A0A2Y9G412
uniprot id: A0A2Y9G6H4
names: Similarity
messages: Belongs to the GCF family.

29088:LOC110572646
gene id: 29088:LOC110572646
uniprot id: A0A2Y9GFB5
uniprot id: A0A8M1MUD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Nucleus

29088:FAM83E
gene id: 29088:FAM83E
uniprot id: A0A2Y9GFV9
names: Similarity
messages: Belongs to the FAM83 family.

29088:LOC110571397
gene id: 29088:LOC110571397
uniprot id: A0A2Y9HDM9
uniprot id: A0A8M1MDI2
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:HACD4
gene id: 29088:HACD4
uniprot id: A0A2Y9HMP5
uniprot id: A0A8M1MTL7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:WNT7A
gene id: 29088:WNT7A
uniprot id: A0A2Y9HGD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

29088:PPP1CA
gene id: 29088:PPP1CA
uniprot id: A0A2Y9GNF4
uniprot id: A0A8M1MP92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: nucleolus
messages: nucleoplasm

29088:TMEM150A
gene id: 29088:TMEM150A
uniprot id: A0A2Y9HTI4
names: Subcellular Location Annotation
messages: Membrane

29088:SCN9A
gene id: 29088:SCN9A
uniprot id: A0A2Y9I522
uniprot id: A0A2Y9I981
uniprot id: A0A2Y9IBN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

29088:FOXO4
gene id: 29088:FOXO4
uniprot id: A0A2Y9GAQ3
uniprot id: A0A8M1M1B5
names: Subcellular Location Annotation
messages: Nucleus

29088:LSS
gene id: 29088:LSS
uniprot id: A0A2Y9G781
uniprot id: A0A2Y9G9R9
uniprot id: A0A2Y9GAT3
uniprot id: A0A8M1MMZ3
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

29088:DDX18
gene id: 29088:DDX18
uniprot id: A0A2Y9HI63
uniprot id: A0A2Y9HIL3
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

29088:SLC66A3
gene id: 29088:SLC66A3
uniprot id: A0A2Y9HNQ9
uniprot id: A0A2Y9HP13
uniprot id: A0A8M1MLT2
names: Subcellular Location Annotation
messages: Membrane

29088:FUT9
gene id: 29088:FUT9
uniprot id: A0A2Y9HII9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

29088:GON4L
gene id: 29088:GON4L
uniprot id: A0A2Y9GIJ0
uniprot id: A0A8M1MD62
uniprot id: A0A8M1MFC9
names: Subcellular Location Annotation
messages: Nucleus

29088:THNSL1
gene id: 29088:THNSL1
uniprot id: A0A2Y9GU65
names: Similarity
messages: Belongs to the threonine synthase family.

29088:LOC110578072
gene id: 29088:LOC110578072
uniprot id: A0A8M1MD33
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

29088:RBM46
gene id: 29088:RBM46
uniprot id: A0A2Y9HZ50
uniprot id: A0A8M1M7R4
names: Subcellular Location Annotation
messages: Cytoplasm

29088:ADD2
gene id: 29088:ADD2
uniprot id: A0A2Y9HSQ3
uniprot id: A0A2Y9HT66
uniprot id: A0A2Y9HT84
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

29088:LOC110571534
gene id: 29088:LOC110571534
uniprot id: A0A2Y9G8M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane

29088:ATAD2
gene id: 29088:ATAD2
uniprot id: A0A8M1M9P9
names: Similarity
messages: Belongs to the AAA ATPase family.

29088:LOC110586885
gene id: 29088:LOC110586885
uniprot id: A0A8M1MG65
uniprot id: A0A8M1MI98
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus speckle
messages: nuclear body

29088:ALDH1L1
gene id: 29088:ALDH1L1
uniprot id: A0A8M1M7Z6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

29088:TLE2
gene id: 29088:TLE2
uniprot id: A0A8M1ML12
uniprot id: A0A8M1MPB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

29088:LOC110576170
gene id: 29088:LOC110576170
uniprot id: A0A2Y9GNS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:TRMU
gene id: 29088:TRMU
uniprot id: A0A2Y9GWA9
uniprot id: A0A8M1MCW9
names: Function
names: Similarity
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.

29088:DOCK5
gene id: 29088:DOCK5
uniprot id: A0A8M1M3Q2
names: Similarity
messages: Belongs to the DOCK family.

29088:SLC22A4
gene id: 29088:SLC22A4
uniprot id: A0A2Y9I7J9
uniprot id: A0A8M1MFQ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Basal cell membrane
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
messages: Interacts with PDZK1.

29088:DIP2B
gene id: 29088:DIP2B
uniprot id: A0A2Y9I9H7
uniprot id: A0A8M1MBY3
uniprot id: A0A8M1MC33
names: Similarity
messages: Belongs to the DIP2 family.

29088:ELOVL2
gene id: 29088:ELOVL2
uniprot id: A0A2Y9HMQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL2 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:PHYHIPL
gene id: 29088:PHYHIPL
uniprot id: A0A2Y9HUD7
names: Similarity
messages: Belongs to the PHYHIP family.

29088:LOC110587553
gene id: 29088:LOC110587553
uniprot id: A0A8M1MP33
names: Similarity
messages: Belongs to the NDK family.

29088:ELOVL1
gene id: 29088:ELOVL1
uniprot id: A0A2Y9GJZ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family. ELOVL1 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.
messages: Endoplasmic reticulum membrane
messages: Interacts with LASS2, TECR and HSD17B12.
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

29088:ISL1
gene id: 29088:ISL1
uniprot id: A0A2Y9HRT1
names: Subcellular Location Annotation
messages: Nucleus

29088:NMB
gene id: 29088:NMB
uniprot id: A0A2Y9GB40
uniprot id: A0A2Y9GB99
uniprot id: A0A8M1MJS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bombesin/neuromedin-B/ranatensin family.
messages: Secreted
messages: neuron projection

29088:PIM1
gene id: 29088:PIM1
uniprot id: A0A2Y9GM71
uniprot id: A0A2Y9GMC8
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

29088:PKN2
gene id: 29088:PKN2
uniprot id: A0A2Y9H703
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cleavage furrow
messages: Midbody
messages: Nucleus

29088:GPR108
gene id: 29088:GPR108
uniprot id: A0A2Y9IAF8
uniprot id: A0A8M1MKD0
uniprot id: A0A8M1MKE4
uniprot id: A0A8M1MKE7
uniprot id: A0A8M1MME2
uniprot id: A0A8M1MMF7
uniprot id: A0A8M1MUH0
names: Subcellular Location Annotation
messages: Membrane

29088:YIPF4
gene id: 29088:YIPF4
uniprot id: A0A2Y9HMX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:IL17A
gene id: 29088:IL17A
uniprot id: A0A2Y9H834
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

29088:MYO1A
gene id: 29088:MYO1A
uniprot id: A0A2Y9GUQ7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

29088:LOC110591202
gene id: 29088:LOC110591202
uniprot id: A0A2Y9I8B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-3 family.
messages: Secreted

29088:SLC35D2
gene id: 29088:SLC35D2
uniprot id: A0A2Y9G5Y8
names: Subcellular Location Annotation
messages: Membrane

29088:RIMKLB
gene id: 29088:RIMKLB
uniprot id: A0A2Y9H384
names: Similarity
messages: Belongs to the RimK family.

29088:ALDH18A1
gene id: 29088:ALDH18A1
uniprot id: A0A2Y9HTQ5
uniprot id: A0A8M1MF67
names: Similarity
messages: In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
messages: In the N-terminal section; belongs to the glutamate 5-kinase family.

29088:BMPR2
gene id: 29088:BMPR2
uniprot id: A0A8M1M782
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

29088:NOL6
gene id: 29088:NOL6
uniprot id: A0A8M1MSU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAP family.
messages: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
messages: nucleolus

29088:MMP12
gene id: 29088:MMP12
uniprot id: A0A2Y9HKB7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

29088:CLIC2
gene id: 29088:CLIC2
uniprot id: A0A2Y9GGM1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

29088:PPDPF
gene id: 29088:PPDPF
uniprot id: A0A8M1MLQ8
names: Similarity
messages: Belongs to the PPDPF family.

29088:LOC110581020
gene id: 29088:LOC110581020
uniprot id: A0A2Y9H451
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcitonin family.
messages: Secreted
messages: Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.

29088:CLDN9
gene id: 29088:CLDN9
uniprot id: A0A2Y9HQR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

29088:C10H2orf49
gene id: 29088:C10H2orf49
uniprot id: A0A2Y9GE82
uniprot id: A0A8M1MVG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ashwin family.
messages: Nucleus

29088:GOT2
gene id: 29088:GOT2
uniprot id: A0A2Y9I871
uniprot id: A0A8M1M2P2
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

29088:SNCA
gene id: 29088:SNCA
uniprot id: A0A2Y9I2M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synuclein family.
messages: Membrane
messages: Nucleus
messages: Secreted
messages: Synapse
messages: axon

29088:CASP8
gene id: 29088:CASP8
uniprot id: A0A2Y9I959
names: Similarity
messages: Belongs to the peptidase C14A family.

29088:LOC110590308
gene id: 29088:LOC110590308
uniprot id: A0A2Y9HYJ0
uniprot id: A0A2Y9HYN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lambda interferon family.
messages: Secreted

29088:DDX59
gene id: 29088:DDX59
uniprot id: A0A2Y9GGD1
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX59 subfamily.

29088:SOAT1
gene id: 29088:SOAT1
uniprot id: A0A2Y9GH71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:POLD2
gene id: 29088:POLD2
uniprot id: A0A2Y9I5U3
uniprot id: A0A2Y9I656
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Nucleus

29088:PRKCE
gene id: 29088:PRKCE
uniprot id: A0A2Y9HYS6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin-dependent signaling, by mediating angiotensin-2-induced activation of integrin beta-1 (ITGB1) in cardiac fibroblasts. Phosphorylates MARCKS, which phosphorylates and activates PTK2/FAK, leading to the spread of cardiomyocytes. Involved in the control of the directional transport of ITGB1 in mesenchymal cells by phosphorylating vimentin (VIM), an intermediate filament (IF) protein. In epithelial cells, associates with and phosphorylates keratin-8 (KRT8), which induces targeting of desmoplakin at desmosomes and regulates cell-cell contact. Phosphorylates IQGAP1, which binds to CDC42, mediating epithelial cell-cell detachment prior to migration.
messages: Cell membrane
messages: Cytoplasm
messages: Novel PKCs (PRKCD, PRKCE, PRKCH and PRKCQ) are calcium-insensitive, but activated by diacylglycerol (DAG) and phosphatidylserine.
messages: Nucleus
messages: cytoskeleton
messages: perinuclear region

29088:NAPSA
gene id: 29088:NAPSA
uniprot id: A0A2Y9GGF6
names: Similarity
messages: Belongs to the peptidase A1 family.

29088:GATA1
gene id: 29088:GATA1
uniprot id: A0A2Y9G6F8
names: Subcellular Location Annotation
messages: Nucleus

29088:RIF1
gene id: 29088:RIF1
uniprot id: A0A8M1MDX9
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

29088:BCLAF3
gene id: 29088:BCLAF3
uniprot id: A0A8M1M3Q8
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

29088:PTPRD
gene id: 29088:PTPRD
uniprot id: A0A8M1MS58
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

29088:LOC110574510
gene id: 29088:LOC110574510
uniprot id: A0A2Y9GI98
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ANAPC4
gene id: 29088:ANAPC4
uniprot id: A0A2Y9GBH2
names: Function
names: Similarity
messages: Belongs to the APC4 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.

29088:CCND1
gene id: 29088:CCND1
uniprot id: A0A2Y9GVJ4
names: Similarity
messages: Belongs to the cyclin family.

29088:C3H2orf76
gene id: 29088:C3H2orf76
uniprot id: A0A2Y9HIF1
uniprot id: A0A2Y9HIT5
uniprot id: A0A2Y9HIU0
names: Similarity
messages: Belongs to the UPF0538 family.

29088:LOC110581025
gene id: 29088:LOC110581025
uniprot id: A0A2Y9H443
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

29088:LOC110578849
gene id: 29088:LOC110578849
uniprot id: A0A2Y9GXV3
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110579375
gene id: 29088:LOC110579375
uniprot id: A0A2Y9GZH7
names: Similarity
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

29088:LOC110591637
gene id: 29088:LOC110591637
uniprot id: A0A2Y9I2P3
names: Similarity
messages: Belongs to the ARTD/PARP family.

29088:HCRTR2
gene id: 29088:HCRTR2
uniprot id: A0A2Y9HEN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:DOK3
gene id: 29088:DOK3
uniprot id: A0A2Y9HSK8
uniprot id: A0A8M1MQ19
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

29088:SUGP2
gene id: 29088:SUGP2
uniprot id: A0A2Y9GLC6
names: Subcellular Location Annotation
messages: Nucleus

29088:KCNG2
gene id: 29088:KCNG2
uniprot id: A0A2Y9GR90
names: Subcellular Location Annotation
messages: Membrane

29088:ATP13A1
gene id: 29088:ATP13A1
uniprot id: A0A2Y9GNL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

29088:GNG11
gene id: 29088:GNG11
uniprot id: A0A2Y9H610
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

29088:BCHE
gene id: 29088:BCHE
uniprot id: A0A2Y9I3F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

29088:ADGRL1
gene id: 29088:ADGRL1
uniprot id: A0A2Y9IAX3
uniprot id: A0A8M1M0B3
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110576954
gene id: 29088:LOC110576954
uniprot id: A0A2Y9GRF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

29088:SLC4A8
gene id: 29088:SLC4A8
uniprot id: A0A8M1MB91
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

29088:TEKT2
gene id: 29088:TEKT2
uniprot id: A0A2Y9GJN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

29088:ALAS2
gene id: 29088:ALAS2
uniprot id: A0A8M1M3I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

29088:IL15
gene id: 29088:IL15
uniprot id: A0A2Y9G7N8
uniprot id: A0A2Y9G7V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

29088:SUCLG1
gene id: 29088:SUCLG1
uniprot id: A0A2Y9HUC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with the ATP-specific beta subunit SUCLA2, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with the GTP-specific beta subunit SUCLG2 forms a GDP-forming succinyl-CoA synthetase (G-SCS).
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.

29088:SMPD3
gene id: 29088:SMPD3
uniprot id: A0A2Y9I9Y1
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

29088:ACKR3
gene id: 29088:ACKR3
uniprot id: A0A2Y9G6I4
uniprot id: A0A2Y9G900
uniprot id: A0A2Y9GA28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:OTX1
gene id: 29088:OTX1
uniprot id: A0A2Y9HZU7
names: Subcellular Location Annotation
messages: Nucleus

29088:GTPBP4
gene id: 29088:GTPBP4
uniprot id: A0A2Y9HBA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

29088:ACER2
gene id: 29088:ACER2
uniprot id: A0A8M1MUI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:SART1
gene id: 29088:SART1
uniprot id: A0A2Y9GNA1
uniprot id: A0A2Y9GU15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNU66/SART1 family.
messages: Nucleus

29088:SARS1
gene id: 29088:SARS1
uniprot id: A0A2Y9H7U4
uniprot id: A0A8M1MAH5
uniprot id: A0A8M1MBV6
uniprot id: A0A8M1MGF0
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

29088:DCP1B
gene id: 29088:DCP1B
uniprot id: A0A2Y9H3L9
names: Similarity
messages: Belongs to the DCP1 family.

29088:LOC110586908
gene id: 29088:LOC110586908
uniprot id: A0A8M1MLJ5
uniprot id: A0A8M1MS49
names: Subcellular Location Annotation
messages: Secreted

29088:MEA1
gene id: 29088:MEA1
uniprot id: A0A2Y9H854
uniprot id: A0A2Y9HER5
names: Function
messages: May play an important role in spermatogenesis and/or testis development.

29088:CATSPERD
gene id: 29088:CATSPERD
uniprot id: A0A8M1M975
names: Similarity
messages: Belongs to the CATSPERD family.

29088:LOC110570584
gene id: 29088:LOC110570584
uniprot id: A0A8M1MA08
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Belongs to the calycin superfamily. Lipocalin family.

29088:ST3GAL6
gene id: 29088:ST3GAL6
uniprot id: A0A2Y9GWM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

29088:RAD18
gene id: 29088:RAD18
uniprot id: A0A2Y9HGI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD18 family.
messages: Nucleus

29088:SGSH
gene id: 29088:SGSH
uniprot id: A0A2Y9GBQ7
names: Similarity
messages: Belongs to the sulfatase family.

29088:PRKCQ
gene id: 29088:PRKCQ
uniprot id: A0A2Y9HKX9
uniprot id: A0A2Y9HL49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

29088:MIGA1
gene id: 29088:MIGA1
uniprot id: A0A8M1M7Z9
names: Similarity
messages: Belongs to the mitoguardin family.

29088:LOC110573444
gene id: 29088:LOC110573444
uniprot id: A0A2Y9GJH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:FOXE1
gene id: 29088:FOXE1
uniprot id: A0A2Y9H6U5
names: Subcellular Location Annotation
messages: Nucleus

29088:ATP5PB
gene id: 29088:ATP5PB
uniprot id: A0A2Y9H7T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

29088:CCDC188
gene id: 29088:CCDC188
uniprot id: A0A2Y9H4J7
names: Subcellular Location Annotation
messages: Membrane

29088:MRPL15
gene id: 29088:MRPL15
uniprot id: A0A2Y9H437
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

29088:LOC110592974
gene id: 29088:LOC110592974
uniprot id: A0A2Y9I795
uniprot id: A0A2Y9I7J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

29088:ADAT2
gene id: 29088:ADAT2
uniprot id: A0A2Y9HBU9
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily.
messages: Probably participates in deamination of adenosine-34 to inosine in many tRNAs.

29088:LOC110586962
gene id: 29088:LOC110586962
uniprot id: A0A2Y9HMS9
names: Subcellular Location Annotation
messages: Membrane

29088:STING1
gene id: 29088:STING1
uniprot id: A0A2Y9I114
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STING family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Mitochondrion outer membrane
messages: autophagosome membrane
messages: perinuclear region

29088:LOC110592724
gene id: 29088:LOC110592724
uniprot id: A0A2Y9H9C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB4 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:CPA3
gene id: 29088:CPA3
uniprot id: A0A2Y9GWL4
names: Similarity
messages: Belongs to the peptidase M14 family.

29088:HAPLN2
gene id: 29088:HAPLN2
uniprot id: A0A2Y9GET5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:CLIC1
gene id: 29088:CLIC1
uniprot id: A0A2Y9HSL2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cell membrane
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane
messages: Nucleus membrane

29088:TMEM39A
gene id: 29088:TMEM39A
uniprot id: A0A2Y9HEA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

29088:LOC110589091
gene id: 29088:LOC110589091
uniprot id: A0A2Y9HUC6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.

29088:MYC
gene id: 29088:MYC
uniprot id: A0A2Y9GXT0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform.
messages: nucleolus
messages: nucleoplasm

29088:GUCY2F
gene id: 29088:GUCY2F
uniprot id: A0A2Y9G4N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane
messages: Photoreceptor outer segment membrane

29088:PLAC8L1
gene id: 29088:PLAC8L1
uniprot id: A0A2Y9I7X9
names: Similarity
messages: Belongs to the cornifelin family.

29088:GALNT3
gene id: 29088:GALNT3
uniprot id: A0A2Y9I994
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

29088:LOC110585331
gene id: 29088:LOC110585331
uniprot id: A0A2Y9HHV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:NUP107
gene id: 29088:NUP107
uniprot id: A0A2Y9G7Z9
uniprot id: A0A2Y9G942
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup84/Nup107 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: Part of the nuclear pore complex (NPC).
messages: nuclear pore complex

29088:C1H19orf53
gene id: 29088:C1H19orf53
uniprot id: A0A2Y9IAM0
names: Function
names: Similarity
messages: Belongs to the UPF0390 family.
messages: May have a potential role in hypercalcemia of malignancy.

29088:GALNT5
gene id: 29088:GALNT5
uniprot id: A0A2Y9IC26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

29088:FHL5
gene id: 29088:FHL5
uniprot id: A0A2Y9HC83
names: Function
names: Subcellular Location Annotation
messages: May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation-independent manner.
messages: Nucleus

29088:SETDB1
gene id: 29088:SETDB1
uniprot id: A0A2Y9GWU7
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

29088:PHTF1
gene id: 29088:PHTF1
uniprot id: A0A2Y9H2V6
names: Subcellular Location Annotation
messages: Membrane

29088:SMPD1
gene id: 29088:SMPD1
uniprot id: A0A2Y9GQ06
uniprot id: A0A2Y9GQB5
uniprot id: A0A8M1MN40
uniprot id: A0A8M1MQ21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Converts sphingomyelin to ceramide.
messages: Secreted

29088:ROMO1
gene id: 29088:ROMO1
uniprot id: A0A2Y9H643
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR2 family.
messages: Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.
messages: Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
messages: Mitochondrion inner membrane

29088:SCN1B
gene id: 29088:SCN1B
uniprot id: A0A8M1MY11
names: Subcellular Location Annotation
messages: Membrane

29088:MFSD8
gene id: 29088:MFSD8
uniprot id: A0A2Y9GI91
uniprot id: A0A8M1M3V8
uniprot id: A0A8M1M3W3
uniprot id: A0A8M1M466
uniprot id: A0A8M1M6C5
uniprot id: A0A8M1M7U2
uniprot id: A0A8M1MBV2
names: Subcellular Location Annotation
messages: Membrane

29088:NDUFS3
gene id: 29088:NDUFS3
uniprot id: A0A2Y9GPL7
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.

29088:E2F7
gene id: 29088:E2F7
uniprot id: A0A2Y9G7U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

29088:ENTPD2
gene id: 29088:ENTPD2
uniprot id: A0A2Y9H4Z5
uniprot id: A0A8M1MRR5
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

29088:UBA7
gene id: 29088:UBA7
uniprot id: A0A8M1MKA3
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

29088:PSMC5
gene id: 29088:PSMC5
uniprot id: A0A2Y9G568
uniprot id: A0A2Y9G5N9
uniprot id: A0A2Y9G8U2
names: Similarity
messages: Belongs to the AAA ATPase family.

29088:GNA14
gene id: 29088:GNA14
uniprot id: A0A2Y9H0E3
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

29088:AOPEP
gene id: 29088:AOPEP
uniprot id: A0A2Y9G3I5
names: Similarity
messages: Belongs to the peptidase M1 family.

29088:DGKH
gene id: 29088:DGKH
uniprot id: A0A2Y9HPG9
uniprot id: A0A2Y9HW05
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

29088:PSEN1
gene id: 29088:PSEN1
uniprot id: A0A2Y9G8X7
uniprot id: A0A2Y9GCG1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Cytoplasmic granule
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: Synapse
messages: The PAL motif is required for normal active site conformation.
messages: axon
messages: neuron projection

29088:LOC110576451
gene id: 29088:LOC110576451
uniprot id: A0A2Y9GQ27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SLC18A1
gene id: 29088:SLC18A1
uniprot id: A0A2Y9HSP8
uniprot id: A0A2Y9HSQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Membrane
messages: secretory vesicle membrane
messages: synaptic vesicle membrane

29088:RPS19
gene id: 29088:RPS19
uniprot id: A0A2Y9H8A6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

29088:SPRING1
gene id: 29088:SPRING1
uniprot id: A0A2Y9HRQ7
uniprot id: A0A8M1MT33
uniprot id: A0A8M1MT39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPRING family.
messages: Golgi apparatus membrane
messages: Membrane

29088:LOC123324333
gene id: 29088:LOC123324333
uniprot id: A0A8M1MAK3
names: Function
names: Subunit
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

29088:BOLA2B
gene id: 29088:BOLA2B
uniprot id: A0A2Y9I3M4
names: Similarity
messages: Belongs to the BolA/IbaG family.

29088:GLIPR1
gene id: 29088:GLIPR1
uniprot id: A0A2Y9G5C9
names: Similarity
messages: Belongs to the CRISP family.

29088:PGM2
gene id: 29088:PGM2
uniprot id: A0A2Y9I4U3
uniprot id: A0A8M1M866
names: Similarity
messages: Belongs to the phosphohexose mutase family.

29088:GFOD2
gene id: 29088:GFOD2
uniprot id: A0A2Y9I5Y6
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

29088:GPR65
gene id: 29088:GPR65
uniprot id: A0A2Y9G8E4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:RHPN2
gene id: 29088:RHPN2
uniprot id: A0A2Y9HYR9
names: Similarity
messages: Belongs to the RHPN family.

29088:LOC110585868
gene id: 29088:LOC110585868
uniprot id: A0A2Y9HQH1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:HIGD2A
gene id: 29088:HIGD2A
uniprot id: A0A2Y9HZ88
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

29088:LOC110587937
gene id: 29088:LOC110587937
uniprot id: A0A2Y9HQ21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion
messages: Mitochondrion inner membrane

29088:CCL3L3
gene id: 29088:CCL3L3
uniprot id: A0A2Y9I7I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

29088:LOC110572694
gene id: 29088:LOC110572694
uniprot id: A0A8M1M2V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IGFL family.
messages: Secreted

29088:CENPU
gene id: 29088:CENPU
uniprot id: A0A8M1M196
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-U/AME1 family.
messages: Nucleus

29088:DESI2
gene id: 29088:DESI2
uniprot id: A0A2Y9GKJ9
uniprot id: A0A2Y9GMA3
names: Similarity
messages: Belongs to the DeSI family.

29088:MPHOSPH10
gene id: 29088:MPHOSPH10
uniprot id: A0A2Y9GB00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.
messages: nucleolus

29088:TMED4
gene id: 29088:TMED4
uniprot id: A0A2Y9IDA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:ARFGEF1
gene id: 29088:ARFGEF1
uniprot id: A0A2Y9H4U7
uniprot id: A0A8M1MDD8
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: perinuclear region

29088:LPAR4
gene id: 29088:LPAR4
uniprot id: A0A2Y9GYI3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:PPP1R14C
gene id: 29088:PPP1R14C
uniprot id: A0A2Y9HI51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Inhibitor of PPP1CA.
messages: Membrane

29088:PHF5A
gene id: 29088:PHF5A
uniprot id: A0A2Y9GVY2
names: Similarity
messages: Belongs to the PHF5 family.

29088:TNC
gene id: 29088:TNC
uniprot id: A0A2Y9HAR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: extracellular matrix

29088:LOC110585340
gene id: 29088:LOC110585340
uniprot id: A0A2Y9HHW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ARID3C
gene id: 29088:ARID3C
uniprot id: A0A2Y9H6R5
uniprot id: A0A8M1MYL8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Nucleus
messages: Transcription factor.

29088:LOC110569927
gene id: 29088:LOC110569927
uniprot id: A0A8M1MV08
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

29088:SERINC5
gene id: 29088:SERINC5
uniprot id: A0A2Y9I1K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

29088:LOC110591098
gene id: 29088:LOC110591098
uniprot id: A0A8M1MIG9
names: Similarity
messages: Belongs to the SGT1 family.

29088:MUC2
gene id: 29088:MUC2
uniprot id: A0A8M1MRY8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ILK
gene id: 29088:ILK
uniprot id: A0A2Y9GQ16
uniprot id: A0A2Y9GQC5
names: Subcellular Location Annotation
messages: focal adhesion
messages: lamellipodium
messages: sarcomere

29088:SYNJ2
gene id: 29088:SYNJ2
uniprot id: A0A8M1MHH2
uniprot id: A0A8M1MHH9
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

29088:GRM7
gene id: 29088:GRM7
uniprot id: A0A2Y9HFS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

29088:ADAMTS3
gene id: 29088:ADAMTS3
uniprot id: A0A2Y9I964
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:PODXL
gene id: 29088:PODXL
uniprot id: A0A2Y9H9W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the podocalyxin family.
messages: Cell membrane
messages: Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells.
messages: Membrane
messages: Membrane raft
messages: filopodium
messages: lamellipodium
messages: microvillus
messages: ruffle

29088:GPT
gene id: 29088:GPT
uniprot id: A0A2Y9GYD1
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

29088:DIPK2B
gene id: 29088:DIPK2B
uniprot id: A0A2Y9GEZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

29088:CCNDBP1
gene id: 29088:CCNDBP1
uniprot id: A0A2Y9HH76
uniprot id: A0A2Y9HHL2
uniprot id: A0A2Y9HNS4
names: Similarity
names: Subunit
messages: Belongs to the CCNDBP1 family.
messages: Interacts with CCND1 and GRAP2. May also interact with COPS5, RPLP0, SIRT6, SYF2 and TCF3.

29088:DEFB132
gene id: 29088:DEFB132
uniprot id: A0A2Y9H4V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

29088:CD63
gene id: 29088:CD63
uniprot id: A0A2Y9H056
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Cell membrane
messages: Cell surface
messages: Endosome membrane
messages: Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.
messages: Late endosome membrane
messages: Lysosome membrane
messages: Melanosome
messages: Membrane
messages: extracellular exosome
messages: multivesicular body

29088:TMEFF1
gene id: 29088:TMEFF1
uniprot id: A0A2Y9H5T5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:NUDT7
gene id: 29088:NUDT7
uniprot id: A0A2Y9I3V6
uniprot id: A0A2Y9I3W0
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

29088:LOC110580250
gene id: 29088:LOC110580250
uniprot id: A0A2Y9H6W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:IMMP1L
gene id: 29088:IMMP1L
uniprot id: A0A2Y9GP05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family.
messages: Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Mitochondrion inner membrane

29088:GRB10
gene id: 29088:GRB10
uniprot id: A0A8M1MSL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

29088:CIBAR1
gene id: 29088:CIBAR1
uniprot id: A0A2Y9H1J9
uniprot id: A0A8M1M8J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CIBAR family.
messages: centriole
messages: cilium basal body

29088:LOC110586172
gene id: 29088:LOC110586172
uniprot id: A0A8M1MX67
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:CCL24
gene id: 29088:CCL24
uniprot id: A0A2Y9HXJ6
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

29088:SGSM2
gene id: 29088:SGSM2
uniprot id: A0A2Y9I736
uniprot id: A0A2Y9IE59
uniprot id: A0A8M1MU39
uniprot id: A0A8M1MU43
uniprot id: A0A8M1MVX2
uniprot id: A0A8M1MX12
names: Similarity
messages: Belongs to the RUTBC family.

29088:SLC25A36
gene id: 29088:SLC25A36
uniprot id: A0A2Y9G691
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:LSM5
gene id: 29088:LSM5
uniprot id: A0A2Y9H179
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

29088:LOC110588414
gene id: 29088:LOC110588414
uniprot id: A0A8M1M567
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

29088:CRIPT
gene id: 29088:CRIPT
uniprot id: A0A2Y9I5L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRIPT family.
messages: Cytoplasm

29088:SNRPC
gene id: 29088:SNRPC
uniprot id: A0A2Y9GM55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the U1 small nuclear ribonucleoprotein C family.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Nucleus
messages: U1 snRNP is composed of the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.

29088:FAM234B
gene id: 29088:FAM234B
uniprot id: A0A2Y9H3D1
names: Similarity
messages: Belongs to the FAM234 family.

29088:LOC110585707
gene id: 29088:LOC110585707
uniprot id: A0A8M1M6Z6
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

29088:LOC110591371
gene id: 29088:LOC110591371
uniprot id: A0A2Y9I6T4
names: Subcellular Location Annotation
messages: Secreted

29088:ATP6V1B2
gene id: 29088:ATP6V1B2
uniprot id: A0A2Y9HXW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

29088:POFUT2
gene id: 29088:POFUT2
uniprot id: A0A2Y9G6Z9
names: Similarity
messages: Belongs to the glycosyltransferase 68 family.

29088:LOC110573818
gene id: 29088:LOC110573818
uniprot id: A0A2Y9GG43
names: Similarity
messages: Belongs to the CCDC43 family.

29088:MRPS18C
gene id: 29088:MRPS18C
uniprot id: A0A2Y9I235
uniprot id: A0A2Y9I2L4
uniprot id: A0A8M1M801
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Mitochondrion

29088:RNF112
gene id: 29088:RNF112
uniprot id: A0A8M1MXI5
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

29088:USE1
gene id: 29088:USE1
uniprot id: A0A2Y9GLI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:NFE2L1
gene id: 29088:NFE2L1
uniprot id: A0A2Y9I896
uniprot id: A0A2Y9I901
uniprot id: A0A2Y9I904
uniprot id: A0A2Y9ICY1
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

29088:CDK4
gene id: 29088:CDK4
uniprot id: A0A2Y9GUK3
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:TIGD6
gene id: 29088:TIGD6
uniprot id: A0A2Y9HTM8
names: Subcellular Location Annotation
messages: Nucleus

29088:CNKSR3
gene id: 29088:CNKSR3
uniprot id: A0A2Y9HCD9
uniprot id: A0A8M1MSG3
names: Similarity
messages: Belongs to the CNKSR family.

29088:NPC2
gene id: 29088:NPC2
uniprot id: A0A2Y9GBT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPC2 family.
messages: Secreted

29088:TACR3
gene id: 29088:TACR3
uniprot id: A0A2Y9GEJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:USP33
gene id: 29088:USP33
uniprot id: A0A2Y9G6P6
uniprot id: A0A2Y9G7U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: centrosome
messages: perinuclear region

29088:SLC7A4
gene id: 29088:SLC7A4
uniprot id: A0A2Y9H0M7
names: Subcellular Location Annotation
messages: Membrane

29088:NTAQ1
gene id: 29088:NTAQ1
uniprot id: A0A2Y9H262
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NTAQ1 family.
messages: Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.
messages: Monomer.

29088:LOC110592253
gene id: 29088:LOC110592253
uniprot id: A0A8M1MAS0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

29088:PARP2
gene id: 29088:PARP2
uniprot id: A0A2Y9HH57
uniprot id: A0A2Y9HNB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

29088:DIP2C
gene id: 29088:DIP2C
uniprot id: A0A2Y9H4N6
names: Similarity
messages: Belongs to the DIP2 family.

29088:LOC110580048
gene id: 29088:LOC110580048
uniprot id: A0A8M1MTI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Mitochondrion inner membrane

29088:TGM1
gene id: 29088:TGM1
uniprot id: A0A2Y9HHN3
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

29088:ATPAF2
gene id: 29088:ATPAF2
uniprot id: A0A2Y9HF94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

29088:TPMT
gene id: 29088:TPMT
uniprot id: A0A2Y9HLJ8
uniprot id: A0A2Y9HT69
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm
messages: Monomer.

29088:FAM53B
gene id: 29088:FAM53B
uniprot id: A0A2Y9I6C9
names: Similarity
messages: Belongs to the FAM53 family.

29088:LOC110583500
gene id: 29088:LOC110583500
uniprot id: A0A2Y9HC02
uniprot id: A0A2Y9HC80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:VPS26B
gene id: 29088:VPS26B
uniprot id: A0A2Y9HK37
names: Similarity
messages: Belongs to the VPS26 family.

29088:TUT7
gene id: 29088:TUT7
uniprot id: A0A2Y9G3L6
uniprot id: A0A8M1MV93
uniprot id: A0A8M1MYM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Cytoplasm

29088:IFT43
gene id: 29088:IFT43
uniprot id: A0A2Y9G8J6
names: Similarity
messages: Belongs to the IFT43 family.

29088:NRXN1
gene id: 29088:NRXN1
uniprot id: A0A2Y9HZ61
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Presynaptic cell membrane

29088:ITGA1
gene id: 29088:ITGA1
uniprot id: A0A2Y9HN92
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:DKK4
gene id: 29088:DKK4
uniprot id: A0A2Y9GDQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

29088:FUT7
gene id: 29088:FUT7
uniprot id: A0A2Y9H4Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

29088:LOC110579314
gene id: 29088:LOC110579314
uniprot id: A0A2Y9H3P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ATP6V0A1
gene id: 29088:ATP6V0A1
uniprot id: A0A2Y9GEG7
uniprot id: A0A8M1MUX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

29088:CFAP45
gene id: 29088:CFAP45
uniprot id: A0A8M1MDM8
names: Similarity
messages: Belongs to the CFAP45 family.

29088:LOC110578348
gene id: 29088:LOC110578348
uniprot id: A0A2Y9GWH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

29088:DDAH1
gene id: 29088:DDAH1
uniprot id: A0A2Y9H7H8
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

29088:NLGN1
gene id: 29088:NLGN1
uniprot id: A0A2Y9I2T5
uniprot id: A0A2Y9I323
uniprot id: A0A2Y9I3D2
uniprot id: A0A2Y9I7P4
uniprot id: A0A2Y9I9U8
uniprot id: A0A8M1MDT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

29088:NID1
gene id: 29088:NID1
uniprot id: A0A2Y9HJC7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

29088:CERS3
gene id: 29088:CERS3
uniprot id: A0A2Y9GBI0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

29088:TATDN2
gene id: 29088:TATDN2
uniprot id: A0A2Y9HMM9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

29088:LOC110591694
gene id: 29088:LOC110591694
uniprot id: A0A8M1M4P6
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110577470
gene id: 29088:LOC110577470
uniprot id: A0A2Y9GT81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC123323402
gene id: 29088:LOC123323402
uniprot id: A0A8M1M5Q7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

29088:C11H11orf1
gene id: 29088:C11H11orf1
uniprot id: A0A2Y9HKJ7
names: Function
names: Subcellular Location Annotation
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
messages: cilium axoneme

29088:PHOSPHO1
gene id: 29088:PHOSPHO1
uniprot id: A0A2Y9I7J1
uniprot id: A0A2Y9I7U1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

29088:RPS27L
gene id: 29088:RPS27L
uniprot id: A0A2Y9HD31
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

29088:GOLPH3
gene id: 29088:GOLPH3
uniprot id: A0A2Y9HJ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

29088:RRP1B
gene id: 29088:RRP1B
uniprot id: A0A2Y9G713
uniprot id: A0A8M1M646
names: Similarity
messages: Belongs to the RRP1 family.

29088:PROKR1
gene id: 29088:PROKR1
uniprot id: A0A2Y9HYF9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:ZIM2
gene id: 29088:ZIM2
uniprot id: A0A2Y9GFN5
names: Subcellular Location Annotation
messages: Nucleus

29088:HDAC8
gene id: 29088:HDAC8
uniprot id: A0A8M1M1M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

29088:CCNA1
gene id: 29088:CCNA1
uniprot id: A0A2Y9G4M3
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

29088:ARHGEF2
gene id: 29088:ARHGEF2
uniprot id: A0A2Y9GF66
uniprot id: A0A2Y9GFC5
uniprot id: A0A2Y9GFD8
uniprot id: A0A2Y9GII3
uniprot id: A0A2Y9GII5
uniprot id: A0A2Y9GK09
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Golgi apparatus
messages: Vesicle
messages: spindle
messages: tight junction

29088:VGLL1
gene id: 29088:VGLL1
uniprot id: A0A2Y9GN50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.
messages: Nucleus

29088:PLPP4
gene id: 29088:PLPP4
uniprot id: A0A2Y9I1S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

29088:LOC110571755
gene id: 29088:LOC110571755
uniprot id: A0A8M1MLH7
names: Similarity
messages: Belongs to the serpin family.

29088:FBLL1
gene id: 29088:FBLL1
uniprot id: A0A2Y9HQC9
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

29088:KCND2
gene id: 29088:KCND2
uniprot id: A0A2Y9HYU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.2/KCND2 sub-subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: dendrite
messages: dendritic spine

29088:TRPV2
gene id: 29088:TRPV2
uniprot id: A0A2Y9HFG3
uniprot id: A0A8M1MWD2
names: Subcellular Location Annotation
messages: Membrane

29088:SHANK2
gene id: 29088:SHANK2
uniprot id: A0A8M1MPP7
names: Subcellular Location Annotation
messages: Postsynaptic density

29088:TMC6
gene id: 29088:TMC6
uniprot id: A0A2Y9GC99
uniprot id: A0A2Y9GCA4
uniprot id: A0A2Y9GCC0
uniprot id: A0A2Y9GF27
uniprot id: A0A8M1MVK1
uniprot id: A0A8M1MXU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

29088:UFM1
gene id: 29088:UFM1
uniprot id: A0A2Y9G4K9
uniprot id: A0A2Y9G752
names: Function
names: Similarity
messages: Belongs to the UFM1 family.
messages: Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to lysine residues of substrate proteins as a monomer or a lysine-linked polymer. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.

29088:TRDN
gene id: 29088:TRDN
uniprot id: A0A8M1MK40
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

29088:EPGN
gene id: 29088:EPGN
uniprot id: A0A2Y9I2F1
uniprot id: A0A2Y9I949
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:RSBN1
gene id: 29088:RSBN1
uniprot id: A0A2Y9H258
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the round spermatid basic protein 1 family.
messages: Nucleus

29088:PTPN12
gene id: 29088:PTPN12
uniprot id: A0A2Y9H142
uniprot id: A0A2Y9H5T7
uniprot id: A0A2Y9H7J0
uniprot id: A0A8M1MPV5
uniprot id: A0A8M1MPV9
uniprot id: A0A8M1MT45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 4 subfamily.
messages: Cytoplasm
messages: Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.

29088:FAM135A
gene id: 29088:FAM135A
uniprot id: A0A2Y9H7A0
uniprot id: A0A2Y9HE53
uniprot id: A0A8M1MH68
names: Similarity
messages: Belongs to the FAM135 family.

29088:MINDY4B
gene id: 29088:MINDY4B
uniprot id: A0A8M1M1E6
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

29088:CHST7
gene id: 29088:CHST7
uniprot id: A0A2Y9G9T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

29088:CAPN10
gene id: 29088:CAPN10
uniprot id: A0A2Y9GA61
names: Similarity
messages: Belongs to the peptidase C2 family.

29088:TMEM63B
gene id: 29088:TMEM63B
uniprot id: A0A2Y9H7G3
uniprot id: A0A2Y9H7H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

29088:LOC110578730
gene id: 29088:LOC110578730
uniprot id: A0A8M1MGT3
names: Similarity
messages: Belongs to the AAA ATPase family.

29088:GTPBP8
gene id: 29088:GTPBP8
uniprot id: A0A2Y9H8W2
uniprot id: A0A2Y9HEP3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.

29088:ADGRE5
gene id: 29088:ADGRE5
uniprot id: A0A2Y9IB85
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:ADAMTS14
gene id: 29088:ADAMTS14
uniprot id: A0A8M1MIH9
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:ZFPM2
gene id: 29088:ZFPM2
uniprot id: A0A2Y9GXR8
names: Subcellular Location Annotation
messages: Nucleus

29088:TRAPPC9
gene id: 29088:TRAPPC9
uniprot id: A0A2Y9GZ21
uniprot id: A0A8M1M9R9
names: Similarity
messages: Belongs to the NIBP family.

29088:RBP1
gene id: 29088:RBP1
uniprot id: A0A2Y9G5S0
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Belongs to the calycin superfamily. Lipocalin family.

29088:LOC110580249
gene id: 29088:LOC110580249
uniprot id: A0A2Y9H8H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:MTERF2
gene id: 29088:MTERF2
uniprot id: A0A2Y9H1H1
names: Similarity
messages: Belongs to the mTERF family.

29088:PPM1G
gene id: 29088:PPM1G
uniprot id: A0A2Y9HT71
uniprot id: A0A2Y9HUK3
uniprot id: A0A8M1MKZ1
names: Similarity
messages: Belongs to the PP2C family.

29088:LUC7L
gene id: 29088:LUC7L
uniprot id: A0A2Y9HQ22
uniprot id: A0A2Y9HV06
names: Similarity
messages: Belongs to the Luc7 family.

29088:GPR21
gene id: 29088:GPR21
uniprot id: A0A2Y9H6W7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:DNAL4
gene id: 29088:DNAL4
uniprot id: A0A2Y9GZY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

29088:EDIL3
gene id: 29088:EDIL3
uniprot id: A0A2Y9HUH8
uniprot id: A0A2Y9HUI7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:RPL15
gene id: 29088:RPL15
uniprot id: A0A2Y9G6E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Cytoplasm

29088:POMC
gene id: 29088:POMC
uniprot id: A0A2Y9HTY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Anorexigenic peptide. Increases the pigmentation of skin by increasing melanin production in melanocytes.
messages: Belongs to the POMC family.
messages: Endogenous opiate.
messages: Endogenous orexigenic opiate.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

29088:RBM15
gene id: 29088:RBM15
uniprot id: A0A2Y9H2G6
uniprot id: A0A2Y9H2I0
names: Similarity
messages: Belongs to the RRM Spen family.

29088:LOC110575734
gene id: 29088:LOC110575734
uniprot id: A0A8M1MXP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

29088:TMEM138
gene id: 29088:TMEM138
uniprot id: A0A2Y9GN65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM138 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: Vacuole membrane
messages: cilium

29088:LOC110573053
gene id: 29088:LOC110573053
uniprot id: A0A2Y9GDL3
names: Subcellular Location Annotation
messages: Nucleus

29088:BMT2
gene id: 29088:BMT2
uniprot id: A0A2Y9I070
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BMT2 family.
messages: Interacts with the GATOR1 complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine. Interacts with the KICSTOR complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine.
messages: S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 signaling. Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase.

29088:CRABP1
gene id: 29088:CRABP1
uniprot id: A0A2Y9GFI8
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Belongs to the calycin superfamily. Lipocalin family.

29088:LOC110584592
gene id: 29088:LOC110584592
uniprot id: A0A2Y9HFG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

29088:CD44
gene id: 29088:CD44
uniprot id: A0A2Y9GP31
uniprot id: A0A2Y9GP35
uniprot id: A0A2Y9GPA8
uniprot id: A0A2Y9GPB9
uniprot id: A0A2Y9GPF1
uniprot id: A0A2Y9GPF8
uniprot id: A0A2Y9GT70
uniprot id: A0A2Y9GT74
uniprot id: A0A2Y9GT78
uniprot id: A0A2Y9GUV7
uniprot id: A0A2Y9GUW1
uniprot id: A0A2Y9GUW5
uniprot id: A0A8M1MXH2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: microvillus

29088:TSPAN11
gene id: 29088:TSPAN11
uniprot id: A0A2Y9H3Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

29088:LHX2
gene id: 29088:LHX2
uniprot id: A0A2Y9H619
uniprot id: A0A8M1MRN0
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110579802
gene id: 29088:LOC110579802
uniprot id: A0A2Y9H0T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

29088:DNAJC24
gene id: 29088:DNAJC24
uniprot id: A0A2Y9GP01
uniprot id: A0A2Y9GT37
names: Similarity
messages: Belongs to the DPH4 family.

29088:DRC1
gene id: 29088:DRC1
uniprot id: A0A8M1MVC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC1 family.
messages: cilium axoneme
messages: flagellum axoneme

29088:PAX9
gene id: 29088:PAX9
uniprot id: A0A2Y9I4J7
names: Subcellular Location Annotation
messages: Nucleus

29088:FOXA3
gene id: 29088:FOXA3
uniprot id: A0A2Y9GH73
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110569858
gene id: 29088:LOC110569858
uniprot id: A0A2Y9G3P6
uniprot id: A0A2Y9G6V6
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:FGFR3
gene id: 29088:FGFR3
uniprot id: A0A8M1M542
uniprot id: A0A8M1M5E2
uniprot id: A0A8M1M5E7
uniprot id: A0A8M1M7I4
uniprot id: A0A8M1M8Z9
uniprot id: A0A8M1M905
uniprot id: A0A8M1MD70
uniprot id: A0A8M1MD76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Membrane

29088:KRT2
gene id: 29088:KRT2
uniprot id: A0A2Y9GSW1
uniprot id: A0A8M1MBW3
uniprot id: A0A8M1MC11
uniprot id: A0A8M1ME45
uniprot id: A0A8M1MFI2
uniprot id: A0A8M1MFI7
uniprot id: A0A8M1MKE6
names: Similarity
messages: Belongs to the intermediate filament family.

29088:LOC110572022
gene id: 29088:LOC110572022
uniprot id: A0A2Y9GE77
uniprot id: A0A8M1MMU2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

29088:LOC110571471
gene id: 29088:LOC110571471
uniprot id: A0A8M1MIN6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

29088:LOC110573280
gene id: 29088:LOC110573280
uniprot id: A0A2Y9GED1
names: Similarity
messages: Belongs to the intermediate filament family.

29088:PHYKPL
gene id: 29088:PHYKPL
uniprot id: A0A2Y9I1S1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

29088:MAPK14
gene id: 29088:MAPK14
uniprot id: A0A2Y9GMC7
uniprot id: A0A2Y9GR77
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

29088:NUP62CL
gene id: 29088:NUP62CL
uniprot id: A0A2Y9G5E8
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

29088:IDS
gene id: 29088:IDS
uniprot id: A0A2Y9GG97
uniprot id: A0A8M1M181
names: Similarity
messages: Belongs to the sulfatase family.

29088:CDH5
gene id: 29088:CDH5
uniprot id: A0A2Y9IBW0
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

29088:NR1I3
gene id: 29088:NR1I3
uniprot id: A0A2Y9GEM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

29088:SP4
gene id: 29088:SP4
uniprot id: A0A2Y9H1B7
names: Subcellular Location Annotation
messages: Nucleus

29088:TP53INP1
gene id: 29088:TP53INP1
uniprot id: A0A2Y9GX71
uniprot id: A0A2Y9H1K9
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

29088:MRPL1
gene id: 29088:MRPL1
uniprot id: A0A2Y9I2E5
names: Subcellular Location Annotation
messages: Mitochondrion

29088:MYO9A
gene id: 29088:MYO9A
uniprot id: A0A8M1MIM1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

29088:MYO19
gene id: 29088:MYO19
uniprot id: A0A2Y9I7T2
uniprot id: A0A2Y9I8J8
uniprot id: A0A2Y9ICG4
uniprot id: A0A2Y9IF71
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:IRF2
gene id: 29088:IRF2
uniprot id: A0A2Y9HDD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Nucleus

29088:RPS6KB2
gene id: 29088:RPS6KB2
uniprot id: A0A2Y9GNI8
uniprot id: A0A2Y9GNS2
uniprot id: A0A8M1MPR6
uniprot id: A0A8M1MWY5
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

29088:LOC110576093
gene id: 29088:LOC110576093
uniprot id: A0A2Y9GNQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ONECUT1
gene id: 29088:ONECUT1
uniprot id: A0A2Y9HDH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

29088:MAT1A
gene id: 29088:MAT1A
uniprot id: A0A2Y9HV84
uniprot id: A0A2Y9HV90
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

29088:LOC110573134
gene id: 29088:LOC110573134
uniprot id: A0A2Y9GGX0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:KCNJ3
gene id: 29088:KCNJ3
uniprot id: A0A2Y9I543
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

29088:LOC110572111
gene id: 29088:LOC110572111
uniprot id: A0A2Y9GAP2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

29088:LOC110576850
gene id: 29088:LOC110576850
uniprot id: A0A8M1M1X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

29088:LOC110585457
gene id: 29088:LOC110585457
uniprot id: A0A2Y9HHR3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:RTBDN
gene id: 29088:RTBDN
uniprot id: A0A2Y9IIB0
names: Similarity
messages: Belongs to the folate receptor family.

29088:MAMDC4
gene id: 29088:MAMDC4
uniprot id: A0A2Y9H528
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110591411
gene id: 29088:LOC110591411
uniprot id: A0A8M1M8M3
names: Subcellular Location Annotation
messages: Nucleus speckle

29088:TBC1D7
gene id: 29088:TBC1D7
uniprot id: A0A8M1MJK0
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Vesicle

29088:SMIM15
gene id: 29088:SMIM15
uniprot id: A0A2Y9I1A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM15 family.
messages: Membrane

29088:LOC110571974
gene id: 29088:LOC110571974
uniprot id: A0A2Y9GA83
uniprot id: A0A8M1MCW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

29088:CAPRIN1
gene id: 29088:CAPRIN1
uniprot id: A0A2Y9GT54
uniprot id: A0A8M1MRH7
names: Similarity
messages: Belongs to the caprin family.

29088:LOC110570250
gene id: 29088:LOC110570250
uniprot id: A0A2Y9G4C7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

29088:MCF2L
gene id: 29088:MCF2L
uniprot id: A0A8M1MA81
uniprot id: A0A8M1MEL2
names: Subcellular Location Annotation
messages: Cytoplasm

29088:DNAAF3
gene id: 29088:DNAAF3
uniprot id: A0A2Y9GJ21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAAF3 family.
messages: Cytoplasm
messages: Dynein axonemal particle
messages: Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia.

29088:LOC110594224
gene id: 29088:LOC110594224
uniprot id: A0A2Y9IG26
names: Caution
names: Function
names: Similarity
messages: As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:HDAC2
gene id: 29088:HDAC2
uniprot id: A0A2Y9HIV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

29088:GJB6
gene id: 29088:GJB6
uniprot id: A0A2Y9G4B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

29088:LOC110569740
gene id: 29088:LOC110569740
uniprot id: A0A2Y9G5A3
names: Similarity
messages: Belongs to the MORF4 family-associated protein family.

29088:LOC110576425
gene id: 29088:LOC110576425
uniprot id: A0A2Y9GQ12
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SLC26A11
gene id: 29088:SLC26A11
uniprot id: A0A2Y9GBV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

29088:FUT8
gene id: 29088:FUT8
uniprot id: A0A8M1MJK8
uniprot id: A0A8M1MTL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 23 family.
messages: Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
messages: Golgi stack membrane
messages: Membrane

29088:HEXIM1
gene id: 29088:HEXIM1
uniprot id: A0A2Y9GIX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEXIM family.
messages: Nucleus

29088:RNASET2
gene id: 29088:RNASET2
uniprot id: A0A2Y9HBR1
uniprot id: A0A2Y9HHV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Lysosome lumen

29088:NOTCH2
gene id: 29088:NOTCH2
uniprot id: A0A2Y9H2L6
uniprot id: A0A8M1M9R5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

29088:FAM227B
gene id: 29088:FAM227B
uniprot id: A0A8M1MSX4
names: Similarity
messages: Belongs to the FAM227 family.

29088:LOC110583134
gene id: 29088:LOC110583134
uniprot id: A0A2Y9HHJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP14 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm
messages: Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.

29088:PKNOX1
gene id: 29088:PKNOX1
uniprot id: A0A8M1M678
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

29088:AQP3
gene id: 29088:AQP3
uniprot id: A0A2Y9H5K8
uniprot id: A0A8M1MRC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

29088:NFXL1
gene id: 29088:NFXL1
uniprot id: A0A2Y9I6U4
names: Similarity
messages: Belongs to the NFX1 family.

29088:TUBA1C
gene id: 29088:TUBA1C
uniprot id: A0A2Y9IDL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

29088:LOC110583983
gene id: 29088:LOC110583983
uniprot id: A0A2Y9HDI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).
messages: Belongs to the cytochrome P450 family.
messages: Mitochondrion inner membrane

29088:RBM10
gene id: 29088:RBM10
uniprot id: A0A8M1M1X9
uniprot id: A0A8M1M1Y4
uniprot id: A0A8M1M284
uniprot id: A0A8M1M290
uniprot id: A0A8M1M4G3
uniprot id: A0A8M1M601
uniprot id: A0A8M1M606
uniprot id: A0A8M1M9T6
uniprot id: A0A8M1M9U0
names: Subcellular Location Annotation
messages: Nucleus

29088:SMAD4
gene id: 29088:SMAD4
uniprot id: A0A2Y9GS17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

29088:SLC43A3
gene id: 29088:SLC43A3
uniprot id: A0A2Y9GRR4
uniprot id: A0A8M1MRJ6
names: Subcellular Location Annotation
messages: Membrane

29088:SRPRA
gene id: 29088:SRPRA
uniprot id: A0A2Y9HKC4
uniprot id: A0A8M1MP21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:LOC110592082
gene id: 29088:LOC110592082
uniprot id: A0A2Y9I8Z0
names: Subcellular Location Annotation
messages: Membrane

29088:DNM3
gene id: 29088:DNM3
uniprot id: A0A2Y9GGL6
uniprot id: A0A2Y9GGQ6
uniprot id: A0A2Y9GJZ3
uniprot id: A0A2Y9GLP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: Cytoplasm

29088:LOC110571736
gene id: 29088:LOC110571736
uniprot id: A0A8M1MLJ6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:LCLAT1
gene id: 29088:LCLAT1
uniprot id: A0A2Y9HMX2
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

29088:MMACHC
gene id: 29088:MMACHC
uniprot id: A0A2Y9GK15
uniprot id: A0A2Y9GQC1
names: Similarity
messages: Belongs to the MMACHC family.

29088:KCNH8
gene id: 29088:KCNH8
uniprot id: A0A2Y9G9K7
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

29088:SUGP1
gene id: 29088:SUGP1
uniprot id: A0A2Y9GHY4
uniprot id: A0A2Y9GI35
names: Subcellular Location Annotation
messages: Nucleus

29088:PROC
gene id: 29088:PROC
uniprot id: A0A2Y9HIX0
uniprot id: A0A8M1MDT0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:ACVR1C
gene id: 29088:ACVR1C
uniprot id: A0A2Y9I449
uniprot id: A0A2Y9I4Q0
uniprot id: A0A2Y9IBD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

29088:SNX31
gene id: 29088:SNX31
uniprot id: A0A2Y9GYL6
names: Similarity
messages: Belongs to the sorting nexin family.

29088:RFTN1
gene id: 29088:RFTN1
uniprot id: A0A8M1MLC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

29088:CAPN14
gene id: 29088:CAPN14
uniprot id: A0A2Y9HNN0
names: Similarity
messages: Belongs to the peptidase C2 family.

29088:LOC110574668
gene id: 29088:LOC110574668
uniprot id: A0A2Y9GIW9
uniprot id: A0A2Y9GMH8
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110576496
gene id: 29088:LOC110576496
uniprot id: A0A2Y9GQ64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:PRKX
gene id: 29088:PRKX
uniprot id: A0A2Y9GEY4
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:LOC110574198
gene id: 29088:LOC110574198
uniprot id: A0A2Y9GHD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

29088:PARVB
gene id: 29088:PARVB
uniprot id: A0A2Y9GVX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: Cell membrane

29088:LHX5
gene id: 29088:LHX5
uniprot id: A0A2Y9HRW7
names: Subcellular Location Annotation
messages: Nucleus

29088:LFNG
gene id: 29088:LFNG
uniprot id: A0A8M1MBQ1
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110572244
gene id: 29088:LOC110572244
uniprot id: A0A2Y9GB19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:SLC46A1
gene id: 29088:SLC46A1
uniprot id: A0A2Y9I7H3
uniprot id: A0A8M1MZ54
names: Subcellular Location Annotation
messages: Membrane

29088:FABP3
gene id: 29088:FABP3
uniprot id: A0A2Y9GL01
uniprot id: A0A2Y9GPS6
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Belongs to the calycin superfamily. Lipocalin family.

29088:SYBU
gene id: 29088:SYBU
uniprot id: A0A2Y9H377
uniprot id: A0A8M1MCE3
names: Subcellular Location Annotation
messages: Membrane

29088:SFRP4
gene id: 29088:SFRP4
uniprot id: A0A2Y9GHM7
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:HOPX
gene id: 29088:HOPX
uniprot id: A0A2Y9I0B7
names: Subcellular Location Annotation
messages: Nucleus

29088:NPR1
gene id: 29088:NPR1
uniprot id: A0A2Y9GER8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

29088:LOC110586922
gene id: 29088:LOC110586922
uniprot id: A0A8M1MR15
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

29088:LOC110594228
gene id: 29088:LOC110594228
uniprot id: A0A2Y9ICG7
names: Similarity
messages: Belongs to the cytochrome b5 family.

29088:PDGFA
gene id: 29088:PDGFA
uniprot id: A0A2Y9GA33
uniprot id: A0A2Y9GA52
uniprot id: A0A8M1MBF5
uniprot id: A0A8M1MEX5
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

29088:P4HA3
gene id: 29088:P4HA3
uniprot id: A0A8M1MXW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

29088:TUBG1
gene id: 29088:TUBG1
uniprot id: A0A2Y9GE46
uniprot id: A0A8M1MVN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation.
messages: centrosome

29088:NIPSNAP1
gene id: 29088:NIPSNAP1
uniprot id: A0A2Y9I5D1
uniprot id: A0A2Y9I5K5
names: Similarity
messages: Belongs to the NipSnap family.

29088:SF3A2
gene id: 29088:SF3A2
uniprot id: A0A2Y9IEY3
names: Similarity
messages: Belongs to the SF3A2 family.

29088:TMEM131L
gene id: 29088:TMEM131L
uniprot id: A0A8M1M8H4
names: Similarity
messages: Belongs to the TMEM131 family.

29088:HTR3A
gene id: 29088:HTR3A
uniprot id: A0A2Y9HKH8
uniprot id: A0A8M1MQR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane

29088:SLC35C2
gene id: 29088:SLC35C2
uniprot id: A0A2Y9GZC2
uniprot id: A0A2Y9GZC5
names: Subcellular Location Annotation
messages: Membrane

29088:MAL
gene id: 29088:MAL
uniprot id: A0A2Y9HN72
uniprot id: A0A2Y9HNN6
uniprot id: A0A2Y9HTM1
names: Subcellular Location Annotation
messages: Membrane

29088:SDE2
gene id: 29088:SDE2
uniprot id: A0A2Y9G851
uniprot id: A0A2Y9G892
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDE2 family.
messages: Cytoplasm
messages: Nucleus

29088:USP20
gene id: 29088:USP20
uniprot id: A0A2Y9H5Q4
uniprot id: A0A2Y9HCI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: centrosome
messages: perinuclear region

29088:CD109
gene id: 29088:CD109
uniprot id: A0A8M1MH32
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.

29088:DGKB
gene id: 29088:DGKB
uniprot id: A0A2Y9H0Z4
uniprot id: A0A2Y9H153
uniprot id: A0A2Y9H156
uniprot id: A0A2Y9H5U1
uniprot id: A0A2Y9H5U7
uniprot id: A0A2Y9H7J9
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

29088:CREG1
gene id: 29088:CREG1
uniprot id: A0A2Y9GGU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

29088:MAGT1
gene id: 29088:MAGT1
uniprot id: A0A2Y9GWY7
uniprot id: A0A2Y9GX25
uniprot id: A0A2Y9GXH7
uniprot id: A0A2Y9H0Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:EIF3M
gene id: 29088:EIF3M
uniprot id: A0A2Y9GP84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Belongs to the eIF-3 subunit M family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm

29088:LOC110569757
gene id: 29088:LOC110569757
uniprot id: A0A2Y9G6F7
names: Similarity
messages: Belongs to the SLBP family.

29088:TADA1
gene id: 29088:TADA1
uniprot id: A0A2Y9GH85
uniprot id: A0A2Y9GHA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TADA1 family.
messages: Component of the STAGA transcription coactivator-HAT complex, at least composed of SUPT3H, GCN5L2, TAF5L, TAF6L, SUPT7L, TADA3L, TAD1L, TAF10, TAF12, TRRAP and TAF9.
messages: Nucleus
messages: Probably involved in transcriptional regulation.

29088:ATP5IF1
gene id: 29088:ATP5IF1
uniprot id: A0A8M1MFX5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase inhibitor family.
messages: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase.
messages: Forms an alpha-helical dimer with monomers associated via an antiparallel alpha-helical coiled coil, leaving each N-terminal inhibitory region accessible for interaction with an F1 catalytic domain. The inhibitory N-terminal region binds the alpha(ADP-bound)-beta(ADP-bound) (ATP5F1A-ATP5F1B) interface of F1-ATPase, and also contact the central gamma subunit (ATP5F1C). This dimeric state is favored by pH values below 7.0, and at higher values the dimers associate to form inactive homotetramer, where the inhibitory region is occluded, masking its inhibitory activity.
messages: Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0.
messages: Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
messages: Mitochondrion

29088:LOC110594255
gene id: 29088:LOC110594255
uniprot id: A0A8M1M2R3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

29088:FOXP2
gene id: 29088:FOXP2
uniprot id: A0A2Y9HTI5
uniprot id: A0A2Y9HU18
uniprot id: A0A2Y9HU19
uniprot id: A0A2Y9HYX1
uniprot id: A0A8M1MQ86
uniprot id: A0A8M1MQ91
uniprot id: A0A8M1MQ95
uniprot id: A0A8M1MQ99
uniprot id: A0A8M1MS50
uniprot id: A0A8M1MS54
uniprot id: A0A8M1MTH9
uniprot id: A0A8M1MY92
uniprot id: A0A8M1MY93
names: Subcellular Location Annotation
messages: Nucleus

29088:BCLAF1
gene id: 29088:BCLAF1
uniprot id: A0A2Y9HCC5
uniprot id: A0A2Y9HIU8
uniprot id: A0A8M1MSD2
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

29088:IL18R1
gene id: 29088:IL18R1
uniprot id: A0A2Y9GAF1
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

29088:DDX56
gene id: 29088:DDX56
uniprot id: A0A2Y9I5V7
uniprot id: A0A2Y9I671
uniprot id: A0A8M1MS45
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

29088:DMTN
gene id: 29088:DMTN
uniprot id: A0A2Y9HS18
uniprot id: A0A8M1M3F4
uniprot id: A0A8M1M5X6
uniprot id: A0A8M1M7F4
uniprot id: A0A8M1M7H0
uniprot id: A0A8M1MBE0
uniprot id: A0A8M1MBF7
uniprot id: A0A8M1MBG3
names: Subcellular Location Annotation
messages: Cytoplasm

29088:ACVRL1
gene id: 29088:ACVRL1
uniprot id: A0A2Y9I940
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

29088:SOX2
gene id: 29088:SOX2
uniprot id: A0A2Y9HEY7
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110576493
gene id: 29088:LOC110576493
uniprot id: A0A2Y9GPY6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:TMEM181
gene id: 29088:TMEM181
uniprot id: A0A8M1MJB5
uniprot id: A0A8M1MKM4
uniprot id: A0A8M1MR53
names: Subcellular Location Annotation
messages: Membrane

29088:SGK1
gene id: 29088:SGK1
uniprot id: A0A2Y9HIR7
uniprot id: A0A8M1MHW5
uniprot id: A0A8M1MHW6
uniprot id: A0A8M1MLA2
uniprot id: A0A8M1MRU8
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

29088:APOA5
gene id: 29088:APOA5
uniprot id: A0A7F3SAB1
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

29088:RIPOR1
gene id: 29088:RIPOR1
uniprot id: A0A2Y9I666
uniprot id: A0A2Y9I6Q3
uniprot id: A0A8M1M4Q2
uniprot id: A0A8M1M8D8
names: Similarity
messages: Belongs to the RIPOR family.

29088:DYNLT5
gene id: 29088:DYNLT5
uniprot id: A0A2Y9G9M5
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

29088:PROX2
gene id: 29088:PROX2
uniprot id: A0A8M1MJI5
names: Subcellular Location Annotation
messages: Nucleus

29088:PTGES2
gene id: 29088:PTGES2
uniprot id: A0A2Y9H5S7
uniprot id: A0A2Y9HCJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GST superfamily.
messages: Membrane

29088:ARHGEF3
gene id: 29088:ARHGEF3
uniprot id: A0A2Y9HGD4
uniprot id: A0A8M1MZ13
uniprot id: A0A8M1MZ14
names: Function
names: Subcellular Location Annotation
messages: Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
messages: Cytoplasm

29088:PTK2
gene id: 29088:PTK2
uniprot id: A0A2Y9GZ26
uniprot id: A0A2Y9GZ42
uniprot id: A0A8M1M9S3
uniprot id: A0A8M1M9S8
uniprot id: A0A8M1MA01
uniprot id: A0A8M1MA07
uniprot id: A0A8M1MC46
uniprot id: A0A8M1MC52
uniprot id: A0A8M1MDI1
uniprot id: A0A8M1MDI6
names: Subcellular Location Annotation
messages: Cell membrane
messages: cell cortex
messages: focal adhesion

29088:LOC110574523
gene id: 29088:LOC110574523
uniprot id: A0A2Y9GI94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:WNT6
gene id: 29088:WNT6
uniprot id: A0A2Y9I4L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

29088:PCLO
gene id: 29088:PCLO
uniprot id: A0A2Y9H1R3
names: Subcellular Location Annotation
messages: Presynaptic active zone

29088:FAM110A
gene id: 29088:FAM110A
uniprot id: A0A2Y9GZG3
names: Similarity
messages: Belongs to the FAM110 family.

29088:CAP1
gene id: 29088:CAP1
uniprot id: A0A2Y9GL47
uniprot id: A0A2Y9GPX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane
messages: Membrane

29088:PPP4R3A
gene id: 29088:PPP4R3A
uniprot id: A0A2Y9G902
uniprot id: A0A2Y9GBM7
uniprot id: A0A8M1MKR7
names: Similarity
messages: Belongs to the SMEK family.

29088:TAFA2
gene id: 29088:TAFA2
uniprot id: A0A2Y9G5S8
names: Similarity
messages: Belongs to the TAFA family.

29088:PIAS1
gene id: 29088:PIAS1
uniprot id: A0A2Y9HIP1
names: Similarity
messages: Belongs to the PIAS family.

29088:TMEM258
gene id: 29088:TMEM258
uniprot id: A0A2Y9GRY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST5 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

29088:SH3BP4
gene id: 29088:SH3BP4
uniprot id: A0A2Y9G6H5
names: Subcellular Location Annotation
messages: Nucleus
messages: Vesicle
messages: clathrin-coated pit
messages: clathrin-coated vesicle

29088:HIP1
gene id: 29088:HIP1
uniprot id: A0A2Y9HWP3
names: Similarity
messages: Belongs to the SLA2 family.

29088:TGIF2LX
gene id: 29088:TGIF2LX
uniprot id: A0A2Y9HAB5
names: Subcellular Location Annotation
messages: Nucleus

29088:ATF1
gene id: 29088:ATF1
uniprot id: A0A2Y9IDM5
uniprot id: A0A8M1ME63
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110588725
gene id: 29088:LOC110588725
uniprot id: A0A8M1MN55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the U1 small nuclear ribonucleoprotein C family.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Nucleus
messages: U1 snRNP is composed of the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.

29088:LOC110578906
gene id: 29088:LOC110578906
uniprot id: A0A8M1M8E8
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

29088:TNS4
gene id: 29088:TNS4
uniprot id: A0A2Y9IEU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

29088:NUBP1
gene id: 29088:NUBP1
uniprot id: A0A2Y9HPS4
uniprot id: A0A8M1MEP7
uniprot id: A0A8M1ML23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Cell projection
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains. Interacts with KIFC1.

29088:NIPAL4
gene id: 29088:NIPAL4
uniprot id: A0A2Y9I5G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

29088:RPL5
gene id: 29088:RPL5
uniprot id: A0A2Y9H2E5
uniprot id: A0A8M1M9N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

29088:CRYBG2
gene id: 29088:CRYBG2
uniprot id: A0A2Y9GKS8
uniprot id: A0A2Y9GL29
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

29088:RXRA
gene id: 29088:RXRA
uniprot id: A0A8M1MR48
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

29088:CSF2
gene id: 29088:CSF2
uniprot id: A0A2Y9I1D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GM-CSF family.
messages: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
messages: Monomer. The signaling GM-CSF receptor complex is a dodecamer of two head-to-head hexamers of two alpha, two beta, and two ligand subunits.
messages: Secreted

29088:KIF9
gene id: 29088:KIF9
uniprot id: A0A8M1MUZ5
uniprot id: A0A8M1MV01
uniprot id: A0A8M1MWQ6
uniprot id: A0A8M1MZ84
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LSM14A
gene id: 29088:LSM14A
uniprot id: A0A2Y9HXP3
uniprot id: A0A2Y9HY06
uniprot id: A0A2Y9I2M4
uniprot id: A0A8M1M0K8
uniprot id: A0A8M1M0L3
uniprot id: A0A8M1M0W2
uniprot id: A0A8M1M0W8
uniprot id: A0A8M1M354
uniprot id: A0A8M1M4P1
uniprot id: A0A8M1M8C7
uniprot id: A0A8M1M8D2
names: Similarity
messages: Belongs to the LSM14 family.

29088:LOC110592694
gene id: 29088:LOC110592694
uniprot id: A0A2Y9IAV7
uniprot id: A0A2Y9IDH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCP1 family.
messages: May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ).
messages: Nucleus
messages: spindle pole

29088:ATG4B
gene id: 29088:ATG4B
uniprot id: A0A2Y9G6S4
uniprot id: A0A2Y9G6T2
uniprot id: A0A8M1MB08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

29088:ENO4
gene id: 29088:ENO4
uniprot id: A0A2Y9HV57
names: Similarity
messages: Belongs to the enolase family.

29088:LOC110580321
gene id: 29088:LOC110580321
uniprot id: A0A8M1MBT1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

29088:NSFL1C
gene id: 29088:NSFL1C
uniprot id: A0A2Y9GYZ1
uniprot id: A0A8M1MMQ4
uniprot id: A0A8M1MUT7
names: Subcellular Location Annotation
names: Subunit
messages: Golgi stack
messages: Part of a ternary complex containing STX5A, NSFL1C and VCP. NSFL1C forms a homotrimer that binds to one end of a VCP homohexamer. The complex binds to membranes enriched in phosphatidylethanolamine-containing lipids and promotes Golgi membrane fusion. Interaction with VCIP135 leads to dissociation of the complex via ATP hydrolysis by VCP. Binds ubiquitin and mono-ubiquitinated proteins via its N-terminal UBA-like domain when bound to VCP.

29088:OPALIN
gene id: 29088:OPALIN
uniprot id: A0A2Y9HVT1
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Central nervous system-specific myelin protein that increase myelin genes expression during oligodendrocyte differentiation. Promotes oligodendrocyte terminal differentiation.
messages: Membrane

29088:PIGU
gene id: 29088:PIGU
uniprot id: A0A2Y9GZF1
uniprot id: A0A2Y9H415
uniprot id: A0A8M1MPF9
uniprot id: A0A8M1MWP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:JAK1
gene id: 29088:JAK1
uniprot id: A0A2Y9G9Q3
uniprot id: A0A2Y9GDB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system

29088:MLLT1
gene id: 29088:MLLT1
uniprot id: A0A2Y9IEM7
names: Subcellular Location Annotation
messages: Nucleus

29088:COG4
gene id: 29088:COG4
uniprot id: A0A2Y9I4T1
uniprot id: A0A8M1M024
uniprot id: A0A8M1M0C8
uniprot id: A0A8M1M2M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG4 family.
messages: Golgi apparatus membrane

29088:PHETA1
gene id: 29088:PHETA1
uniprot id: A0A8M1MTG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Forms homodimers and heterodimers with PHETA. Interacts with OCRL and INPP5B.
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

29088:TRMT5
gene id: 29088:TRMT5
uniprot id: A0A2Y9HZS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

29088:RANBP9
gene id: 29088:RANBP9
uniprot id: A0A2Y9HM89
uniprot id: A0A2Y9HTX6
names: Similarity
messages: Belongs to the RANBP9/10 family.

29088:FAM8A1
gene id: 29088:FAM8A1
uniprot id: A0A2Y9HS40
names: Subcellular Location Annotation
messages: Membrane

29088:NCAN
gene id: 29088:NCAN
uniprot id: A0A2Y9GLB2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aggrecan/versican proteoglycan family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:ICAM2
gene id: 29088:ICAM2
uniprot id: A0A2Y9G5E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

29088:KCNAB1
gene id: 29088:KCNAB1
uniprot id: A0A2Y9I2Q2
uniprot id: A0A2Y9I2Z6
uniprot id: A0A2Y9I399
uniprot id: A0A2Y9I7L9
uniprot id: A0A2Y9I9R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

29088:CDK10
gene id: 29088:CDK10
uniprot id: A0A2Y9IBG0
uniprot id: A0A2Y9ICA0
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:STK33
gene id: 29088:STK33
uniprot id: A0A2Y9GVY1
uniprot id: A0A8M1MRQ8
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:FIGN
gene id: 29088:FIGN
uniprot id: A0A2Y9I4L6
names: Similarity
messages: Belongs to the AAA ATPase family.

29088:ATAD2B
gene id: 29088:ATAD2B
uniprot id: A0A2Y9HTI7
uniprot id: A0A8M1MNB1
names: Similarity
messages: Belongs to the AAA ATPase family.

29088:LOC110585541
gene id: 29088:LOC110585541
uniprot id: A0A2Y9HHX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:MCIDAS
gene id: 29088:MCIDAS
uniprot id: A0A2Y9I1A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the geminin family.
messages: Nucleus

29088:TMEM63C
gene id: 29088:TMEM63C
uniprot id: A0A2Y9G8B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

29088:MRPL50
gene id: 29088:MRPL50
uniprot id: A0A2Y9H660
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL50 family.
messages: Mitochondrion

29088:SLC52A2
gene id: 29088:SLC52A2
uniprot id: A0A2Y9GYW4
uniprot id: A0A2Y9GZ65
uniprot id: A0A2Y9H3J2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

29088:CFAP97
gene id: 29088:CFAP97
uniprot id: A0A2Y9HDX7
uniprot id: A0A8M1M952
names: Similarity
messages: Belongs to the CFAP97 family.

29088:SLC26A3
gene id: 29088:SLC26A3
uniprot id: A0A2Y9GHJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Mediates chloride-bicarbonate exchange with a chloride bicarbonate stoichiometry of 2:1 in the intestinal epithelia. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation.
messages: Membrane

29088:EMP2
gene id: 29088:EMP2
uniprot id: A0A2Y9HVD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion.
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Membrane raft
messages: Nucleus
messages: perinuclear region

29088:LOC110572009
gene id: 29088:LOC110572009
uniprot id: A0A8M1MCU4
uniprot id: A0A8M1MCZ2
uniprot id: A0A8M1MF18
uniprot id: A0A8M1MLG1
names: Similarity
messages: Belongs to the TPD52 family.

29088:AGPS
gene id: 29088:AGPS
uniprot id: A0A2Y9I414
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
messages: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids.
messages: Homodimer.
messages: Peroxisome

29088:NRN1L
gene id: 29088:NRN1L
uniprot id: A0A2Y9IBH7
names: Similarity
messages: Belongs to the neuritin family.

29088:CHRNA3
gene id: 29088:CHRNA3
uniprot id: A0A8M1MIT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:IL6
gene id: 29088:IL6
uniprot id: A0A2Y9H184
uniprot id: A0A2Y9H1C7
uniprot id: A0A2Y9H1E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-6 superfamily.
messages: Component of a hexamer of two molecules each of IL6, IL6R and IL6ST; first binds to IL6R to associate with the signaling subunit IL6ST. Interacts with IL6R (via the N-terminal ectodomain); this interaction may be affected by IL6R-binding with SORL1, hence decreasing IL6 cis signaling. Interacts with SORL1 (via the N-terminal ectodomain); this interaction leads to IL6 internalization and lysosomal degradation. May form a trimeric complex with the soluble SORL1 ectodomain and soluble IL6R receptor; this interaction might stabilize circulating IL6, hence promoting IL6 trans signaling.
messages: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.
messages: IL6 is a potent inducer of the acute phase response. Rapid production of IL6 contributes to host defense during infection and tissue injury, but excessive IL6 synthesis is involved in disease pathology. In the innate immune response, is synthesized by myeloid cells, such as macrophages and dendritic cells, upon recognition of pathogens through toll-like receptors (TLRs) at the site of infection or tissue injury (By similarity). In the adaptive immune response, is required for the differentiation of B cells into immunoglobulin-secreting cells. Plays a major role in the differentiation of CD4(+) T cell subsets. Essential factor for the development of T follicular helper (Tfh) cells that are required for the induction of germinal-center formation. Required to drive naive CD4(+) T cells to the Th17 lineage. Also required for proliferation of myeloma cells and the survival of plasmablast cells.
messages: Secreted

29088:AFMID
gene id: 29088:AFMID
uniprot id: A0A2Y9GG60
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynurenine formamidase family.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
messages: Homodimer.
messages: Nucleus
messages: The main chain amide nitrogen atoms of the second glycine and its adjacent residue in the HGGXW motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.
messages: cytosol

29088:CPOX
gene id: 29088:CPOX
uniprot id: A0A2Y9GWD6
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

29088:LOC110573000
gene id: 29088:LOC110573000
uniprot id: A0A2Y9GDP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:ASPH
gene id: 29088:ASPH
uniprot id: A0A8M1M9M7
uniprot id: A0A8M1MC00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.
messages: Membrane

29088:MIA2
gene id: 29088:MIA2
uniprot id: A0A2Y9HZR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Plays a role in the regulation of neuronal activity.
messages: Rough endoplasmic reticulum membrane

29088:CHD8
gene id: 29088:CHD8
uniprot id: A0A2Y9HIH9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. CHD8 subfamily.
messages: DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive genes. Involved in both enhancer blocking and epigenetic remodeling at chromatin boundary via its interaction with CTCF. Acts as a suppressor of STAT3 activity by suppressing the LIF-induced STAT3 transcriptional activity. Also acts as a transcription activator via its interaction with ZNF143 by participating in efficient U6 RNA polymerase III transcription.
messages: Interacts with p53/TP53, histone H1, CTNNB1, CTCF and PIAS3. Component of some MLL1/MLL complex, at least composed of the core components KMT2A/MLL1, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, KAT8/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. Interacts with CHD7. Interacts with FAM124B.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Sumoylated.

29088:CHD1
gene id: 29088:CHD1
uniprot id: A0A8M1MFH1
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110593448
gene id: 29088:LOC110593448
uniprot id: A0A2Y9I9H3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

29088:LPCAT3
gene id: 29088:LPCAT3
uniprot id: A0A2Y9H8P5
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110572450
gene id: 29088:LOC110572450
uniprot id: A0A2Y9GBJ3
names: Similarity
messages: Belongs to the fructosamine kinase family.

29088:VMA21
gene id: 29088:VMA21
uniprot id: A0A2Y9GPA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the V0 complex of the vacuolar ATPase (V-ATPase).
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

29088:LOC110579982
gene id: 29088:LOC110579982
uniprot id: A0A2Y9H5X9
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:SHCBP1
gene id: 29088:SHCBP1
uniprot id: A0A2Y9I9J1
uniprot id: A0A2Y9IDX6
uniprot id: A0A2Y9IGP7
names: Subcellular Location Annotation
messages: spindle

29088:LOC110577427
gene id: 29088:LOC110577427
uniprot id: A0A8M1MA73
uniprot id: A0A8M1MAF6
uniprot id: A0A8M1MCJ5
names: Similarity
messages: Belongs to the intermediate filament family.

29088:EMC2
gene id: 29088:EMC2
uniprot id: A0A2Y9H1Y4
uniprot id: A0A8M1MB06
uniprot id: A0A8M1MH02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

29088:GRHPR
gene id: 29088:GRHPR
uniprot id: A0A2Y9H707
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

29088:FAM214B
gene id: 29088:FAM214B
uniprot id: A0A2Y9H657
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATOS family.
messages: Nucleus

29088:SERPINA5
gene id: 29088:SERPINA5
uniprot id: A0A2Y9G8T4
names: Similarity
messages: Belongs to the serpin family.

29088:CDK5R1
gene id: 29088:CDK5R1
uniprot id: A0A2Y9I7S2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit and a regulatory subunit.
messages: Membrane

29088:ESS2
gene id: 29088:ESS2
uniprot id: A0A2Y9H9X8
uniprot id: A0A8M1MVI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESS2 family.
messages: Nucleus

29088:TOMM40L
gene id: 29088:TOMM40L
uniprot id: A0A2Y9GER9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

29088:HSPA4
gene id: 29088:HSPA4
uniprot id: A0A2Y9I1I1
uniprot id: A0A8M1MGU8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm
messages: Interacts with TJP1/ZO-1.

29088:CASP9
gene id: 29088:CASP9
uniprot id: A0A2Y9GP96
uniprot id: A0A8M1M7H8
uniprot id: A0A8M1M7R8
names: Similarity
messages: Belongs to the peptidase C14A family.

29088:RIC3
gene id: 29088:RIC3
uniprot id: A0A2Y9GU76
names: Similarity
messages: Belongs to the ric-3 family.

29088:ALOXE3
gene id: 29088:ALOXE3
uniprot id: A0A8M1MW79
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:AGAP3
gene id: 29088:AGAP3
uniprot id: A0A2Y9HAD4
uniprot id: A0A2Y9HAM5
uniprot id: A0A8M1MQR2
uniprot id: A0A8M1MQR7
uniprot id: A0A8M1MQS0
uniprot id: A0A8M1MSM4
uniprot id: A0A8M1MU00
uniprot id: A0A8M1MYD5
uniprot id: A0A8M1MYD6
names: Similarity
messages: Belongs to the centaurin gamma-like family.

29088:SLF2
gene id: 29088:SLF2
uniprot id: A0A2Y9HVF6
names: Similarity
messages: Belongs to the FAM178 family.

29088:LOC110570817
gene id: 29088:LOC110570817
uniprot id: A0A8M1MQY6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

29088:ANAPC15
gene id: 29088:ANAPC15
uniprot id: A0A2Y9I8V2
uniprot id: A0A2Y9I9G9
uniprot id: A0A2Y9IG58
names: Similarity
messages: Belongs to the APC15 family.

29088:LOC110589589
gene id: 29088:LOC110589589
uniprot id: A0A8M1MDP5
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

29088:NDUFB4
gene id: 29088:NDUFB4
uniprot id: A0A2Y9H9C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB4 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:LOC110577418
gene id: 29088:LOC110577418
uniprot id: A0A2Y9GYV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ADSS2
gene id: 29088:ADSS2
uniprot id: A0A2Y9GGT9
uniprot id: A0A2Y9GLV9
uniprot id: A0A8M1MIC0
uniprot id: A0A8M1MNK1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

29088:HK2
gene id: 29088:HK2
uniprot id: A0A2Y9HTM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hexokinase family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: cytosol

29088:LMNB1
gene id: 29088:LMNB1
uniprot id: A0A2Y9I0C8
uniprot id: A0A8M1MFL8
uniprot id: A0A8M1MHQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: Nucleus lamina

29088:PRKN
gene id: 29088:PRKN
uniprot id: A0A2Y9HB64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RBR family. Parkin subfamily.
messages: Forms an E3 ubiquitin ligase complex.
messages: Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
messages: Mitochondrion
messages: cytosol

29088:CPSF4L
gene id: 29088:CPSF4L
uniprot id: A0A2Y9G7K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

29088:POU4F1
gene id: 29088:POU4F1
uniprot id: A0A8M1M6K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

29088:CRX
gene id: 29088:CRX
uniprot id: A0A2Y9GCU2
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110572701
gene id: 29088:LOC110572701
uniprot id: A0A8M1M2V2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

29088:HMGA2
gene id: 29088:HMGA2
uniprot id: A0A2Y9G7U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGA family.
messages: Nucleus

29088:HNRNPK
gene id: 29088:HNRNPK
uniprot id: A0A2Y9G3K1
uniprot id: A0A2Y9G3M7
uniprot id: A0A2Y9G452
uniprot id: A0A2Y9G652
uniprot id: A0A2Y9G7A2
uniprot id: A0A8M1MVF2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: nucleoplasm
messages: podosome

29088:MYRF
gene id: 29088:MYRF
uniprot id: A0A2Y9GMV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRF family.
messages: Membrane

29088:ST13
gene id: 29088:ST13
uniprot id: A0A2Y9H022
uniprot id: A0A8M1MCY6
names: Similarity
messages: Belongs to the FAM10 family.

29088:CDC37L1
gene id: 29088:CDC37L1
uniprot id: A0A2Y9HKJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

29088:TCFL5
gene id: 29088:TCFL5
uniprot id: A0A2Y9GZR7
uniprot id: A0A8M1MLK4
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110575786
gene id: 29088:LOC110575786
uniprot id: A0A2Y9GMQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110578550
gene id: 29088:LOC110578550
uniprot id: A0A2Y9H3T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:PDGFC
gene id: 29088:PDGFC
uniprot id: A0A2Y9HS39
names: Caution
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:DGKZ
gene id: 29088:DGKZ
uniprot id: A0A2Y9GPJ0
uniprot id: A0A2Y9GTA7
uniprot id: A0A2Y9GUZ0
uniprot id: A0A2Y9GUZ5
uniprot id: A0A8M1MPI2
uniprot id: A0A8M1MPJ2
uniprot id: A0A8M1MRF1
uniprot id: A0A8M1MST2
uniprot id: A0A8M1MXZ3
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

29088:UNC45B
gene id: 29088:UNC45B
uniprot id: A0A2Y9I8B6
uniprot id: A0A2Y9IC81
uniprot id: A0A2Y9IEY7
names: Subcellular Location Annotation
messages: A band
messages: Z line
messages: perinuclear region

29088:RBFOX1
gene id: 29088:RBFOX1
uniprot id: A0A2Y9HQ98
uniprot id: A0A2Y9HV74
uniprot id: A0A2Y9HWQ9
uniprot id: A0A8M1MAV8
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

29088:FEN1
gene id: 29088:FEN1
uniprot id: A0A2Y9GV70
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Mitochondrion
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

29088:MED16
gene id: 29088:MED16
uniprot id: A0A8M1MKP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 16 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

29088:WNT3
gene id: 29088:WNT3
uniprot id: A0A2Y9G560
uniprot id: A0A2Y9G7N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

29088:NDUFC1
gene id: 29088:NDUFC1
uniprot id: A0A2Y9GA57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFC1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:PDE6G
gene id: 29088:PDE6G
uniprot id: A0A2Y9GBP1
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

29088:LOC110573779
gene id: 29088:LOC110573779
uniprot id: A0A8M1MVA8
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

29088:LOC110572112
gene id: 29088:LOC110572112
uniprot id: A0A2Y9GEP0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

29088:DHRS7C
gene id: 29088:DHRS7C
uniprot id: A0A2Y9HF63
uniprot id: A0A2Y9HLG3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29088:GPR15
gene id: 29088:GPR15
uniprot id: A0A2Y9H0S4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:CAMK2D
gene id: 29088:CAMK2D
uniprot id: A0A2Y9GLZ5
uniprot id: A0A2Y9GM54
uniprot id: A0A8M1M4N2
uniprot id: A0A8M1M4N7
uniprot id: A0A8M1M4Y4
uniprot id: A0A8M1M734
uniprot id: A0A8M1M739
uniprot id: A0A8M1M8K2
uniprot id: A0A8M1MCP6
uniprot id: A0A8M1MCQ2
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

29088:LOC110591809
gene id: 29088:LOC110591809
uniprot id: A0A8M1M9T9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

29088:IL17REL
gene id: 29088:IL17REL
uniprot id: A0A8M1MD02
names: Subcellular Location Annotation
messages: Cell membrane

29088:PLIN1
gene id: 29088:PLIN1
uniprot id: A0A8M1MU93
names: Similarity
messages: Belongs to the perilipin family.

29088:GPN3
gene id: 29088:GPN3
uniprot id: A0A2Y9HRF6
uniprot id: A0A8M1MVP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

29088:ALLC
gene id: 29088:ALLC
uniprot id: A0A2Y9HVE9
names: Function
names: Similarity
messages: Belongs to the allantoicase family.
messages: The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals.

29088:GPR83
gene id: 29088:GPR83
uniprot id: A0A2Y9G9B3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:SENP5
gene id: 29088:SENP5
uniprot id: A0A2Y9H8F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C48 family.
messages: nucleolus

29088:SAP30
gene id: 29088:SAP30
uniprot id: A0A2Y9HS33
uniprot id: A0A8M1M3R6
names: Similarity
messages: Belongs to the SAP30 family.

29088:SLC25A3
gene id: 29088:SLC25A3
uniprot id: A0A2Y9GVI5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Interacts with PPIF; the interaction is impaired by CsA.
messages: Membrane
messages: Mitochondrion inner membrane

29088:CPAMD8
gene id: 29088:CPAMD8
uniprot id: A0A2Y9GNH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

29088:LOC110572958
gene id: 29088:LOC110572958
uniprot id: A0A2Y9GDG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Component of a complex at least composed of URM1, CTU2/NCS2 and CTU1/ATPBD3. May form a heterodimer with CTU2/NCS2.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

29088:ITPK1
gene id: 29088:ITPK1
uniprot id: A0A8M1MJ22
names: Similarity
messages: Belongs to the ITPK1 family.

29088:RIN2
gene id: 29088:RIN2
uniprot id: A0A2Y9HXG9
uniprot id: A0A2Y9I2G7
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

29088:MVB12A
gene id: 29088:MVB12A
uniprot id: A0A2Y9GI15
uniprot id: A0A2Y9GI81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

29088:LEUTX
gene id: 29088:LEUTX
uniprot id: A0A2Y9HY61
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110587786
gene id: 29088:LOC110587786
uniprot id: A0A2Y9HPI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the globin family.
messages: Heterotetramer of two alpha chains and two beta chains.
messages: Involved in oxygen transport from the lung to the various peripheral tissues.

29088:UBE2S
gene id: 29088:UBE2S
uniprot id: A0A2Y9GFP4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

29088:LOC110571130
gene id: 29088:LOC110571130
uniprot id: A0A8M1M1Y1
names: Similarity
messages: Belongs to the Gfa family.

29088:KCNK18
gene id: 29088:KCNK18
uniprot id: A0A2Y9I101
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

29088:NRXN2
gene id: 29088:NRXN2
uniprot id: A0A2Y9GTV9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110577784
gene id: 29088:LOC110577784
uniprot id: A0A2Y9GUJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110576504
gene id: 29088:LOC110576504
uniprot id: A0A2Y9GQ69
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:TMOD2
gene id: 29088:TMOD2
uniprot id: A0A2Y9HD63
uniprot id: A0A2Y9HJA1
uniprot id: A0A2Y9HJN6
names: Subcellular Location Annotation
messages: cytoskeleton

29088:SWI5
gene id: 29088:SWI5
uniprot id: A0A8M1MR88
names: Function
names: Similarity
messages: Belongs to the SWI5/SAE3 family.
messages: Component of the swi5-sfr1 complex, a complex required for double-strand break repair via homologous recombination.

29088:TRAPPC6B
gene id: 29088:TRAPPC6B
uniprot id: A0A2Y9HZ67
uniprot id: A0A2Y9HZD6
uniprot id: A0A2Y9HZL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

29088:LOC110592049
gene id: 29088:LOC110592049
uniprot id: A0A2Y9I8W3
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

29088:LOC110584967
gene id: 29088:LOC110584967
uniprot id: A0A2Y9HMW2
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

29088:EPB42
gene id: 29088:EPB42
uniprot id: A0A2Y9HH65
uniprot id: A0A2Y9HH68
uniprot id: A0A2Y9HHG5
uniprot id: A0A2Y9HNC4
uniprot id: A0A2Y9HNR9
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.

29088:DEUP1
gene id: 29088:DEUP1
uniprot id: A0A2Y9G6V8
names: Similarity
messages: Belongs to the CEP63 family.

29088:P3H2
gene id: 29088:P3H2
uniprot id: A0A8M1M968
names: Similarity
messages: Belongs to the leprecan family.

29088:LOC110571115
gene id: 29088:LOC110571115
uniprot id: A0A8M1M8T4
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110581278
gene id: 29088:LOC110581278
uniprot id: A0A2Y9HAF2
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

29088:LOC110585807
gene id: 29088:LOC110585807
uniprot id: A0A8M1M6F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
messages: Nucleus

29088:GLRA1
gene id: 29088:GLRA1
uniprot id: A0A2Y9HSV7
uniprot id: A0A2Y9HU70
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: dendrite

29088:HOXC8
gene id: 29088:HOXC8
uniprot id: A0A2Y9H6I5
names: Subcellular Location Annotation
messages: Nucleus

29088:CEBPZ
gene id: 29088:CEBPZ
uniprot id: A0A2Y9HN19
uniprot id: A0A8M1MPH1
names: Similarity
messages: Belongs to the CBF/MAK21 family.

29088:GAD2
gene id: 29088:GAD2
uniprot id: A0A2Y9GUB9
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

29088:VAC14
gene id: 29088:VAC14
uniprot id: A0A2Y9I924
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAC14 family.
messages: Endosome membrane
messages: Microsome membrane

29088:ADGRE3
gene id: 29088:ADGRE3
uniprot id: A0A2Y9IHY6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:RBM15B
gene id: 29088:RBM15B
uniprot id: A0A2Y9HMA5
names: Similarity
messages: Belongs to the RRM Spen family.

29088:SLC35F6
gene id: 29088:SLC35F6
uniprot id: A0A2Y9HNA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLC35F solute transporter family.
messages: Interacts with SLC25A5.
messages: May play a role as a nucleotide-sugar transporter.
messages: Membrane
messages: Mitochondrion

29088:ING3
gene id: 29088:ING3
uniprot id: A0A2Y9HTV8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

29088:PDE2A
gene id: 29088:PDE2A
uniprot id: A0A2Y9I8F8
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

29088:TAS2R9
gene id: 29088:TAS2R9
uniprot id: A0A2Y9HA09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

29088:RYR3
gene id: 29088:RYR3
uniprot id: A0A2Y9HNF7
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

29088:MYO1B
gene id: 29088:MYO1B
uniprot id: A0A2Y9I593
uniprot id: A0A2Y9I9G2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

29088:LOC110575790
gene id: 29088:LOC110575790
uniprot id: A0A2Y9GRP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:OGFOD1
gene id: 29088:OGFOD1
uniprot id: A0A2Y9ID13
uniprot id: A0A2Y9IFS4
uniprot id: A0A8M1MVY3
names: Similarity
messages: Belongs to the TPA1 family.

29088:ORC6
gene id: 29088:ORC6
uniprot id: A0A2Y9IGE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

29088:PITHD1
gene id: 29088:PITHD1
uniprot id: A0A2Y9GMT1
uniprot id: A0A2Y9GPG5
uniprot id: A0A8M1MBC6
names: Similarity
messages: Belongs to the PITHD1 family.

29088:LOC110576179
gene id: 29088:LOC110576179
uniprot id: A0A2Y9GNZ6
names: Subcellular Location Annotation
messages: Membrane

29088:WDFY1
gene id: 29088:WDFY1
uniprot id: A0A2Y9GHM2
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

29088:CALHM2
gene id: 29088:CALHM2
uniprot id: A0A2Y9I1S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

29088:STRN
gene id: 29088:STRN
uniprot id: A0A2Y9HN59
uniprot id: A0A8M1MLH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

29088:LANCL3
gene id: 29088:LANCL3
uniprot id: A0A2Y9GH11
names: Similarity
messages: Belongs to the LanC-like protein family.

29088:PRKACA
gene id: 29088:PRKACA
uniprot id: A0A2Y9IBD9
uniprot id: A0A8M1MKM2
uniprot id: A0A8M1MSJ8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

29088:MRPL30
gene id: 29088:MRPL30
uniprot id: A0A2Y9HYZ5
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

29088:ICAM5
gene id: 29088:ICAM5
uniprot id: A0A2Y9IB68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

29088:PGF
gene id: 29088:PGF
uniprot id: A0A2Y9GAV9
uniprot id: A0A8M1MMK9
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

29088:AASDH
gene id: 29088:AASDH
uniprot id: A0A2Y9I083
uniprot id: A0A8M1M4F8
uniprot id: A0A8M1M832
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

29088:LPL
gene id: 29088:LPL
uniprot id: A0A2Y9HZF3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Cell membrane
messages: Homodimer. Interacts with APOC2; the interaction activates LPL activity in the presence of lipids.
messages: Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Tyrosine nitration after lipopolysaccharide (LPS) challenge down-regulates the lipase activity.
messages: extracellular matrix

29088:LOC110590930
gene id: 29088:LOC110590930
uniprot id: A0A8M1MQV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

29088:CRKL
gene id: 29088:CRKL
uniprot id: A0A2Y9GWH3
uniprot id: A0A8M1MSM6
names: Similarity
messages: Belongs to the CRK family.

29088:LOC110586272
gene id: 29088:LOC110586272
uniprot id: A0A8M1MNU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:NUP58
gene id: 29088:NUP58
uniprot id: A0A2Y9G480
uniprot id: A0A8M1M5V9
names: Subcellular Location Annotation
messages: nuclear pore complex

29088:PTCD2
gene id: 29088:PTCD2
uniprot id: A0A2Y9I317
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTCD2 family.
messages: Mitochondrion

29088:ABCB1
gene id: 29088:ABCB1
uniprot id: A0A2Y9H1A3
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110589166
gene id: 29088:LOC110589166
uniprot id: A0A2Y9HUQ4
uniprot id: A0A2Y9HUR0
uniprot id: A0A8M1MDX8
names: Subcellular Location Annotation
messages: Cell junction
messages: Golgi stack
messages: Synapse
messages: cytoskeleton

29088:LOC110573839
gene id: 29088:LOC110573839
uniprot id: A0A2Y9GL62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

29088:FBN1
gene id: 29088:FBN1
uniprot id: A0A2Y9HJ86
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibrillin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:AMER1
gene id: 29088:AMER1
uniprot id: A0A2Y9G838
names: Similarity
messages: Belongs to the Amer family.

29088:ZNF446
gene id: 29088:ZNF446
uniprot id: A0A2Y9H7C2
uniprot id: A0A2Y9HE09
uniprot id: A0A8M1MY63
names: Subcellular Location Annotation
messages: Nucleus

29088:GALK1
gene id: 29088:GALK1
uniprot id: A0A2Y9HDU5
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

29088:OSGEPL1
gene id: 29088:OSGEPL1
uniprot id: A0A2Y9I3V7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Mitochondrion
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

29088:SLC27A2
gene id: 29088:SLC27A2
uniprot id: A0A2Y9HCU9
uniprot id: A0A2Y9HJD6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

29088:RPL35A
gene id: 29088:RPL35A
uniprot id: A0A2Y9H8U9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

29088:LOC110579615
gene id: 29088:LOC110579615
uniprot id: A0A2Y9H0B3
names: Subcellular Location Annotation
messages: Membrane

29088:TAF2
gene id: 29088:TAF2
uniprot id: A0A8M1MH18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF2 family.
messages: Nucleus

29088:L3HYPDH
gene id: 29088:L3HYPDH
uniprot id: A0A2Y9I015
names: Similarity
messages: Belongs to the proline racemase family.

29088:FADD
gene id: 29088:FADD
uniprot id: A0A2Y9GNM4
names: Function
messages: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.

29088:OGG1
gene id: 29088:OGG1
uniprot id: A0A2Y9HLZ5
names: Function
names: Similarity
messages: Belongs to the type-1 OGG1 family.
messages: DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion.

29088:FAM163A
gene id: 29088:FAM163A
uniprot id: A0A2Y9GGJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

29088:LOC110581674
gene id: 29088:LOC110581674
uniprot id: A0A2Y9HDB1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:EML2
gene id: 29088:EML2
uniprot id: A0A8M1M0J3
uniprot id: A0A8M1M0U6
uniprot id: A0A8M1M4M6
uniprot id: A0A8M1M8A9
names: Similarity
messages: Belongs to the WD repeat EMAP family.

29088:IGF2BP2
gene id: 29088:IGF2BP2
uniprot id: A0A2Y9H8H7
uniprot id: A0A2Y9H8L4
uniprot id: A0A2Y9H8R2
uniprot id: A0A2Y9HE91
uniprot id: A0A2Y9HFB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: P-body
messages: Stress granule

29088:MIS12
gene id: 29088:MIS12
uniprot id: A0A2Y9HEW4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mis12 family.
messages: Component of the MIS12 complex composed of MIS12, DSN1, NSL1 and PMF1. Also interacts with KNL1, CBX3, CBX5, NDC80 and ZWINT.
messages: kinetochore

29088:LOC110576141
gene id: 29088:LOC110576141
uniprot id: A0A2Y9GNT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:INPP5A
gene id: 29088:INPP5A
uniprot id: A0A8M1MEC4
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.

29088:ATP5MC3
gene id: 29088:ATP5MC3
uniprot id: A0A2Y9I3M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

29088:ABRAXAS2
gene id: 29088:ABRAXAS2
uniprot id: A0A2Y9I631
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM175 family. Abro1 subfamily.
messages: Nucleus
messages: spindle pole

29088:RPS7
gene id: 29088:RPS7
uniprot id: A0A2Y9HN30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eS7 family.
messages: centrosome

29088:LOC110576159
gene id: 29088:LOC110576159
uniprot id: A0A2Y9GNR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:CDK7
gene id: 29088:CDK7
uniprot id: A0A2Y9I1L2
uniprot id: A0A2Y9I243
uniprot id: A0A2Y9I8M3
uniprot id: A0A8M1MPY6
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

29088:SLC12A7
gene id: 29088:SLC12A7
uniprot id: A0A8M1MGI8
uniprot id: A0A8M1MGJ1
uniprot id: A0A8M1MJY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

29088:SCMH1
gene id: 29088:SCMH1
uniprot id: A0A2Y9GNE5
uniprot id: A0A8M1M7T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

29088:NAV3
gene id: 29088:NAV3
uniprot id: A0A2Y9G5B9
uniprot id: A0A2Y9G8Z1
names: Similarity
messages: Belongs to the Nav/unc-53 family.

29088:MDFIC
gene id: 29088:MDFIC
uniprot id: A0A2Y9I080
names: Similarity
messages: Belongs to the MDFI family.

29088:CACNA1E
gene id: 29088:CACNA1E
uniprot id: A0A2Y9GGH9
uniprot id: A0A2Y9GGK0
uniprot id: A0A2Y9GLI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents.

29088:WASHC3
gene id: 29088:WASHC3
uniprot id: A0A2Y9GVA7
names: Similarity
messages: Belongs to the CCDC53 family.

29088:ORC4
gene id: 29088:ORC4
uniprot id: A0A2Y9I3L8
uniprot id: A0A2Y9I884
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC4 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication.
messages: Nucleus

29088:VOPP1
gene id: 29088:VOPP1
uniprot id: A0A2Y9IDC7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VOPP1/ECOP family.
messages: Cytoplasmic vesicle membrane
messages: Endosome membrane
messages: Interacts with WWOX (via WW domain).
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

29088:KCNAB3
gene id: 29088:KCNAB3
uniprot id: A0A2Y9HFC4
uniprot id: A0A2Y9HLM3
uniprot id: A0A2Y9HLN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cytoplasm

29088:PSMA8
gene id: 29088:PSMA8
uniprot id: A0A2Y9GRS7
uniprot id: A0A2Y9GRV9
uniprot id: A0A2Y9GVQ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

29088:EFEMP1
gene id: 29088:EFEMP1
uniprot id: A0A2Y9HZ30
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:KLC1
gene id: 29088:KLC1
uniprot id: A0A2Y9G955
uniprot id: A0A2Y9G992
uniprot id: A0A2Y9GBT1
uniprot id: A0A2Y9GCX1
uniprot id: A0A2Y9GCX8
uniprot id: A0A8M1MIK7
uniprot id: A0A8M1MIL3
uniprot id: A0A8M1MLY7
uniprot id: A0A8M1MSK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

29088:LOC110578796
gene id: 29088:LOC110578796
uniprot id: A0A2Y9H433
names: Similarity
messages: Belongs to the SNF7 family.

29088:LOC110581754
gene id: 29088:LOC110581754
uniprot id: A0A2Y9HC68
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

29088:ZNF768
gene id: 29088:ZNF768
uniprot id: A0A8M1MCT0
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110585299
gene id: 29088:LOC110585299
uniprot id: A0A2Y9HNJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:AP1S2
gene id: 29088:AP1S2
uniprot id: A0A2Y9GCL2
uniprot id: A0A2Y9GFK7
uniprot id: A0A8M1M2B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: Membrane
messages: clathrin-coated pit

29088:GTF2H4
gene id: 29088:GTF2H4
uniprot id: A0A8M1MI92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Nucleus

29088:EIF3A
gene id: 29088:EIF3A
uniprot id: A0A2Y9HWH9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3L and EIF3K. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with EIF4G1. Also interacts with KRT7 and PIWIL2.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.

29088:MTG1
gene id: 29088:MTG1
uniprot id: A0A2Y9HMI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Mitochondrion inner membrane
messages: Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity. Displays mitochondrial GTPase activity.

29088:MGST1
gene id: 29088:MGST1
uniprot id: A0A2Y9H3G8
uniprot id: A0A2Y9H3I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

29088:SKI
gene id: 29088:SKI
uniprot id: A0A8M1MB31
names: Similarity
messages: Belongs to the SKI family.

29088:TOB2
gene id: 29088:TOB2
uniprot id: A0A2Y9GV85
names: Similarity
messages: Belongs to the BTG family.

29088:TMEM35B
gene id: 29088:TMEM35B
uniprot id: A0A2Y9GJL1
uniprot id: A0A2Y9GJU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

29088:SNTB2
gene id: 29088:SNTB2
uniprot id: A0A2Y9I545
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

29088:MED7
gene id: 29088:MED7
uniprot id: A0A2Y9HMW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

29088:GSTCD
gene id: 29088:GSTCD
uniprot id: A0A2Y9GAM2
uniprot id: A0A2Y9GEI4
names: Similarity
messages: Belongs to the GSTCD family.

29088:SLC25A40
gene id: 29088:SLC25A40
uniprot id: A0A2Y9H1F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter required for glutathione import into mitochondria. Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles. Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis.
messages: Mitochondrion inner membrane

29088:TMEM106B
gene id: 29088:TMEM106B
uniprot id: A0A2Y9H620
names: Similarity
messages: Belongs to the TMEM106 family.

29088:CCHCR1
gene id: 29088:CCHCR1
uniprot id: A0A2Y9HLG8
uniprot id: A0A8M1MIG7
uniprot id: A0A8M1MIH2
uniprot id: A0A8M1MKI9
uniprot id: A0A8M1MLV1
uniprot id: A0A8M1MSG8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a regulator of keratinocyte proliferation or differentiation.
messages: Nucleus

29088:ADCK2
gene id: 29088:ADCK2
uniprot id: A0A2Y9HA54
uniprot id: A0A2Y9HGQ2
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

29088:MOG
gene id: 29088:MOG
uniprot id: A0A2Y9HMG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Homodimer.
messages: Membrane
messages: Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion.

29088:OGFRL1
gene id: 29088:OGFRL1
uniprot id: A0A2Y9H7Q0
uniprot id: A0A2Y9H7Y3
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

29088:ECI1
gene id: 29088:ECI1
uniprot id: A0A2Y9HQ81
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

29088:DYNC1H1
gene id: 29088:DYNC1H1
uniprot id: A0A2Y9G934
uniprot id: A0A2Y9G968
uniprot id: A0A2Y9GBQ8
names: Similarity
messages: Belongs to the dynein heavy chain family.

29088:TARS3
gene id: 29088:TARS3
uniprot id: A0A2Y9GF54
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

29088:SATB1
gene id: 29088:SATB1
uniprot id: A0A2Y9G624
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

29088:AMELX
gene id: 29088:AMELX
uniprot id: A0A2Y9GKQ5
names: Similarity
messages: Belongs to the amelogenin family.

29088:CLDN10
gene id: 29088:CLDN10
uniprot id: A0A2Y9HJ15
uniprot id: A0A2Y9HPP1
uniprot id: A0A2Y9HQB2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

29088:OGDHL
gene id: 29088:OGDHL
uniprot id: A0A2Y9I1A9
uniprot id: A0A8M1MF68
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

29088:TACR2
gene id: 29088:TACR2
uniprot id: A0A2Y9HW04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:YJU2B
gene id: 29088:YJU2B
uniprot id: A0A2Y9IB88
names: Similarity
messages: Belongs to the CWC16 family.

29088:SMAD5
gene id: 29088:SMAD5
uniprot id: A0A2Y9I186
uniprot id: A0A8M1MPN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

29088:LOC110590979
gene id: 29088:LOC110590979
uniprot id: A0A8M1MI83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

29088:CPNE3
gene id: 29088:CPNE3
uniprot id: A0A2Y9H1H3
names: Similarity
messages: Belongs to the copine family.

29088:LOC110570256
gene id: 29088:LOC110570256
uniprot id: A0A2Y9G4F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

29088:COPG2
gene id: 29088:COPG2
uniprot id: A0A2Y9HT89
uniprot id: A0A2Y9HYM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

29088:LOC110589016
gene id: 29088:LOC110589016
uniprot id: A0A8M1MQF1
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

29088:TUBD1
gene id: 29088:TUBD1
uniprot id: A0A2Y9IEM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Nucleus
messages: centriole
messages: cilium

29088:DUOX2
gene id: 29088:DUOX2
uniprot id: A0A8M1MKH2
uniprot id: A0A8M1MNU0
uniprot id: A0A8M1MUK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
messages: In the N-terminal section; belongs to the peroxidase family.
messages: Membrane

29088:LOC110578610
gene id: 29088:LOC110578610
uniprot id: A0A8M1M9T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the S-100 family.
messages: May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative.
messages: Nucleus envelope

29088:TBC1D31
gene id: 29088:TBC1D31
uniprot id: A0A2Y9GYH0
uniprot id: A0A8M1M8M9
uniprot id: A0A8M1M8N3
uniprot id: A0A8M1M8X2
uniprot id: A0A8M1M8X7
uniprot id: A0A8M1MB20
uniprot id: A0A8M1MB25
uniprot id: A0A8M1MCF8
uniprot id: A0A8M1MCG3
uniprot id: A0A8M1MH23
names: Function
names: Subcellular Location Annotation
messages: Molecular adapter which is involved in cilium biogenesis. Part of a functional complex including OFD1 a centriolar protein involved in cilium assembly. Could regulate the cAMP-dependent phosphorylation of OFD1, and its subsequent ubiquitination by PJA2 which ultimately leads to its proteasomal degradation.
messages: centriolar satellite
messages: cilium basal body

29088:RIMKLA
gene id: 29088:RIMKLA
uniprot id: A0A8M1MBK9
names: Similarity
messages: Belongs to the RimK family.

29088:MERTK
gene id: 29088:MERTK
uniprot id: A0A2Y9HUM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cell membrane
messages: Membrane

29088:RAP2A
gene id: 29088:RAP2A
uniprot id: A0A2Y9HJ05
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Palmitoylated.
messages: Recycling endosome membrane
messages: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form.

29088:NADSYN1
gene id: 29088:NADSYN1
uniprot id: A0A8M1MNG8
names: Similarity
names: Subunit
messages: Homohexamer.
messages: In the C-terminal section; belongs to the NAD synthetase family.

29088:LOC110573415
gene id: 29088:LOC110573415
uniprot id: A0A2Y9GEU4
uniprot id: A0A8M1MGI5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:ENTPD4
gene id: 29088:ENTPD4
uniprot id: A0A2Y9HS78
uniprot id: A0A8M1M662
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

29088:ARMT1
gene id: 29088:ARMT1
uniprot id: A0A2Y9HBH9
names: Domain
names: Function
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
messages: Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response.
messages: Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.

29088:LOC110571705
gene id: 29088:LOC110571705
uniprot id: A0A8M1MJD1
names: Similarity
messages: Belongs to the peptidase C12 family.

29088:NMI
gene id: 29088:NMI
uniprot id: A0A2Y9I488
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NMI family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

29088:HSPA4L
gene id: 29088:HSPA4L
uniprot id: A0A2Y9GDQ4
uniprot id: A0A8M1M7U7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

29088:UBA6
gene id: 29088:UBA6
uniprot id: A0A2Y9I2A0
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

29088:CD70
gene id: 29088:CD70
uniprot id: A0A2Y9IAY7
names: Similarity
messages: Belongs to the tumor necrosis factor family.

29088:LRP3
gene id: 29088:LRP3
uniprot id: A0A2Y9I384
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110585771
gene id: 29088:LOC110585771
uniprot id: A0A8M1MDW3
names: Subcellular Location Annotation
messages: Nucleus

29088:STRIP2
gene id: 29088:STRIP2
uniprot id: A0A2Y9HTZ1
names: Similarity
messages: Belongs to the STRIP family.

29088:CFAP418
gene id: 29088:CFAP418
uniprot id: A0A2Y9H1W5
uniprot id: A0A8M1M8J6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in photoreceptor outer segment disk morphogenesis.
messages: Photoreceptor inner segment

29088:GAB2
gene id: 29088:GAB2
uniprot id: A0A8M1MN86
names: Similarity
messages: Belongs to the GAB family.

29088:SLC6A5
gene id: 29088:SLC6A5
uniprot id: A0A8M1MS41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

29088:LOC110588681
gene id: 29088:LOC110588681
uniprot id: A0A8M1MM22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

29088:HOMER3
gene id: 29088:HOMER3
uniprot id: A0A2Y9GI03
uniprot id: A0A8M1MHP0
uniprot id: A0A8M1MJR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

29088:LOC110576478
gene id: 29088:LOC110576478
uniprot id: A0A2Y9GPX1
names: Subcellular Location Annotation
messages: Membrane

29088:MFSD9
gene id: 29088:MFSD9
uniprot id: A0A2Y9GE87
names: Subcellular Location Annotation
messages: Membrane

29088:CCL21
gene id: 29088:CCL21
uniprot id: A0A2Y9H5C0
uniprot id: A0A2Y9H5D3
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

29088:ARFGEF2
gene id: 29088:ARFGEF2
uniprot id: A0A2Y9GQV5
uniprot id: A0A8M1MLY9
uniprot id: A0A8M1MQ88
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: perinuclear region

29088:CCL19
gene id: 29088:CCL19
uniprot id: A0A2Y9HDF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

29088:LOC110573152
gene id: 29088:LOC110573152
uniprot id: A0A2Y9GIF5
names: Subcellular Location Annotation
messages: ruffle membrane

29088:MED18
gene id: 29088:MED18
uniprot id: A0A8M1MA14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 18 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

29088:SEC24C
gene id: 29088:SEC24C
uniprot id: A0A8M1MHC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

29088:PIP4P1
gene id: 29088:PIP4P1
uniprot id: A0A2Y9HI72
uniprot id: A0A2Y9HPG2
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: phagosome membrane

29088:LOC110576442
gene id: 29088:LOC110576442
uniprot id: A0A8M1MR89
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:NXF3
gene id: 29088:NXF3
uniprot id: A0A2Y9HEW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm

29088:CDC25C
gene id: 29088:CDC25C
uniprot id: A0A2Y9I1E4
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

29088:LOC110585408
gene id: 29088:LOC110585408
uniprot id: A0A2Y9HHL1
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110585500
gene id: 29088:LOC110585500
uniprot id: A0A2Y9HI95
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29088:CPQ
gene id: 29088:CPQ
uniprot id: A0A2Y9H3U6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes the hydrolysis of dipeptides with unsubstituted terminals into amino acids. May play a role in the liberation of thyroxine hormone from its thyroglobulin (Tg) precursor.
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. The monomeric form is inactive while the homodimer is active.
messages: Lysosome

29088:LOC110576156
gene id: 29088:LOC110576156
uniprot id: A0A2Y9GNU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110590776
gene id: 29088:LOC110590776
uniprot id: A0A8M1M7D9
uniprot id: A0A8M1MD19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOSR1 family.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
messages: Membrane

29088:ACTG2
gene id: 29088:ACTG2
uniprot id: A0A2Y9HT86
names: Similarity
messages: Belongs to the actin family.

29088:LOC110575138
gene id: 29088:LOC110575138
uniprot id: A0A2Y9GPA7
uniprot id: A0A8M1MBB4
uniprot id: A0A8M1MHC0
names: Similarity
messages: Belongs to the DDI1 family.

29088:INHA
gene id: 29088:INHA
uniprot id: A0A2Y9I4G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.
messages: Secreted

29088:RNASE10
gene id: 29088:RNASE10
uniprot id: A0A2Y9HNW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

29088:CLASP1
gene id: 29088:CLASP1
uniprot id: A0A8M1M6X6
names: Subcellular Location Annotation
messages: kinetochore

29088:EMSY
gene id: 29088:EMSY
uniprot id: A0A2Y9I984
uniprot id: A0A2Y9ID60
uniprot id: A0A2Y9IFY6
uniprot id: A0A8M1MR35
names: Subcellular Location Annotation
messages: Nucleus

29088:SUGT1
gene id: 29088:SUGT1
uniprot id: A0A2Y9HPB1
uniprot id: A0A8M1M9C2
names: Similarity
messages: Belongs to the SGT1 family.

29088:LOC110572171
gene id: 29088:LOC110572171
uniprot id: A0A8M1MNI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

29088:ROS1
gene id: 29088:ROS1
uniprot id: A0A8M1ML29
uniprot id: A0A8M1MRL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

29088:NMNAT3
gene id: 29088:NMNAT3
uniprot id: A0A2Y9G5W6
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

29088:HAO2
gene id: 29088:HAO2
uniprot id: A0A2Y9H9F0
uniprot id: A0A8M1MBY6
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

29088:CD40LG
gene id: 29088:CD40LG
uniprot id: A0A2Y9GR88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effects, such as B-cell activation, NF-kappa-B signaling and anti-apoptotic signaling.
messages: Belongs to the tumor necrosis factor family.
messages: Cell surface
messages: Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
messages: Homotrimer.

29088:ADSL
gene id: 29088:ADSL
uniprot id: A0A2Y9H1T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

29088:FXYD7
gene id: 29088:FXYD7
uniprot id: A0A2Y9HY37
uniprot id: A0A2Y9I305
uniprot id: A0A2Y9I4U4
uniprot id: A0A8M1MWI6
names: Similarity
messages: Belongs to the FXYD family.

29088:LYG2
gene id: 29088:LYG2
uniprot id: A0A2Y9HZH3
names: Similarity
messages: Belongs to the glycosyl hydrolase 23 family.

29088:TMEM45B
gene id: 29088:TMEM45B
uniprot id: A0A2Y9HR72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

29088:VAPA
gene id: 29088:VAPA
uniprot id: A0A2Y9H5H4
uniprot id: A0A8M1MUW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:CHSY3
gene id: 29088:CHSY3
uniprot id: A0A2Y9I151
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

29088:GNMT
gene id: 29088:GNMT
uniprot id: A0A2Y9H7Z3
uniprot id: A0A8M1MKH9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family.

29088:RXRG
gene id: 29088:RXRG
uniprot id: A0A2Y9HW16
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

29088:LOC110586315
gene id: 29088:LOC110586315
uniprot id: A0A2Y9HKK2
names: Similarity
messages: Belongs to the GroES chaperonin family.

29088:PMM1
gene id: 29088:PMM1
uniprot id: A0A2Y9GV54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

29088:STIM2
gene id: 29088:STIM2
uniprot id: A0A2Y9G878
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:KHDC3L
gene id: 29088:KHDC3L
uniprot id: A0A8M1MKH4
names: Similarity
messages: Belongs to the KHDC1 family.

29088:LOC110575523
gene id: 29088:LOC110575523
uniprot id: A0A2Y9GQS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

29088:ADGRF4
gene id: 29088:ADGRF4
uniprot id: A0A2Y9H7I6
uniprot id: A0A2Y9H7K4
uniprot id: A0A2Y9H7R8
uniprot id: A0A2Y9HD62
names: Subcellular Location Annotation
messages: Membrane

29088:CAPN9
gene id: 29088:CAPN9
uniprot id: A0A2Y9HJJ9
names: Similarity
messages: Belongs to the peptidase C2 family.

29088:LOC110576783
gene id: 29088:LOC110576783
uniprot id: A0A2Y9GUY1
uniprot id: A0A2Y9GWK9
names: Similarity
messages: Belongs to the multicopper oxidase family.

29088:LOC110590846
gene id: 29088:LOC110590846
uniprot id: A0A8M1M5K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:PDE4D
gene id: 29088:PDE4D
uniprot id: A0A2Y9I1K7
uniprot id: A0A2Y9I1T6
uniprot id: A0A2Y9I222
uniprot id: A0A2Y9I228
uniprot id: A0A2Y9I6G5
uniprot id: A0A2Y9I8K7
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

29088:PWP2
gene id: 29088:PWP2
uniprot id: A0A2Y9G9U7
uniprot id: A0A2Y9GAV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PWP2 family.
messages: nucleolus

29088:TRAM2
gene id: 29088:TRAM2
uniprot id: A0A2Y9HDC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

29088:HBP1
gene id: 29088:HBP1
uniprot id: A0A2Y9GHK1
uniprot id: A0A2Y9GKW3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

29088:PRKAR2A
gene id: 29088:PRKAR2A
uniprot id: A0A2Y9GTQ0
uniprot id: A0A8M1MUT6
uniprot id: A0A8M1MZ71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

29088:SLC25A14
gene id: 29088:SLC25A14
uniprot id: A0A2Y9GQ11
uniprot id: A0A8M1M596
uniprot id: A0A8M1M908
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:PGD
gene id: 29088:PGD
uniprot id: A0A2Y9GKS4
uniprot id: A0A8M1MCP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

29088:GJC1
gene id: 29088:GJC1
uniprot id: A0A2Y9GE24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins. Interacts with CNST.
messages: Belongs to the connexin family. Gamma-type subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

29088:PACSIN2
gene id: 29088:PACSIN2
uniprot id: A0A2Y9GV02
uniprot id: A0A8M1MK54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PACSIN family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: caveola
messages: cytoskeleton
messages: ruffle membrane

29088:LOC110587327
gene id: 29088:LOC110587327
uniprot id: A0A8M1MP97
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

29088:CRY1
gene id: 29088:CRY1
uniprot id: A0A2Y9GVE5
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

29088:CFDP1
gene id: 29088:CFDP1
uniprot id: A0A2Y9I3T5
names: Function
names: Subcellular Location Annotation
messages: May play a role during embryogenesis.
messages: kinetochore

29088:LOC110582150
gene id: 29088:LOC110582150
uniprot id: A0A8M1MA40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

29088:CACNA1F
gene id: 29088:CACNA1F
uniprot id: A0A2Y9G617
uniprot id: A0A2Y9G6E0
uniprot id: A0A2Y9G6F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.

29088:MOS
gene id: 29088:MOS
uniprot id: A0A2Y9GXQ6
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:ERC2
gene id: 29088:ERC2
uniprot id: A0A8M1M4N5
names: Subcellular Location Annotation
messages: Cytoplasm

29088:LOC110582189
gene id: 29088:LOC110582189
uniprot id: A0A2Y9HDL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with 90S and pre-40S pre-ribosomal particles.
messages: Belongs to the RRP36 family.
messages: Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
messages: nucleolus

29088:IL17RE
gene id: 29088:IL17RE
uniprot id: A0A2Y9HGA0
uniprot id: A0A8M1MWC3
names: Subcellular Location Annotation
messages: Membrane

29088:AATF
gene id: 29088:AATF
uniprot id: A0A2Y9I8A5
uniprot id: A0A2Y9I909
names: Similarity
messages: Belongs to the AATF family.

29088:MARS2
gene id: 29088:MARS2
uniprot id: A0A2Y9I9D0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

29088:BTF3
gene id: 29088:BTF3
uniprot id: A0A2Y9HWC7
uniprot id: A0A2Y9HWD6
uniprot id: A0A8M1MPI0
names: Similarity
messages: Belongs to the NAC-beta family.

29088:GPR180
gene id: 29088:GPR180
uniprot id: A0A2Y9HIR0
names: Subcellular Location Annotation
messages: Membrane

29088:RPS6KA3
gene id: 29088:RPS6KA3
uniprot id: A0A2Y9GFH9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

29088:ATP8B4
gene id: 29088:ATP8B4
uniprot id: A0A2Y9HD35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

29088:NKX2-3
gene id: 29088:NKX2-3
uniprot id: A0A2Y9HW74
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110591064
gene id: 29088:LOC110591064
uniprot id: A0A8M1MJG6
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

29088:LOC110591485
gene id: 29088:LOC110591485
uniprot id: A0A2Y9I2T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

29088:ASTE1
gene id: 29088:ASTE1
uniprot id: A0A2Y9G6C2
names: Similarity
messages: Belongs to the asteroid family.

29088:DNAJC27
gene id: 29088:DNAJC27
uniprot id: A0A2Y9HVA9
names: Function
names: Subunit
messages: GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling.
messages: Interacts directly with MAPK1 (wild-type and kinase-deficient forms). Interacts directly (in GTP-bound form) with MAP2K1 (wild-type and kinase-deficient forms).

29088:ITPKA
gene id: 29088:ITPKA
uniprot id: A0A2Y9HHN4
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

29088:LOC110573176
gene id: 29088:LOC110573176
uniprot id: A0A2Y9GE19
uniprot id: A0A8M1MWZ2
names: Similarity
messages: Belongs to the intermediate filament family.

29088:ETV5
gene id: 29088:ETV5
uniprot id: A0A2Y9H8X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

29088:MGRN1
gene id: 29088:MGRN1
uniprot id: A0A2Y9HQ31
uniprot id: A0A2Y9HQI5
uniprot id: A0A8M1MG29
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

29088:LOXL4
gene id: 29088:LOXL4
uniprot id: A0A2Y9HZK6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

29088:LOC110589151
gene id: 29088:LOC110589151
uniprot id: A0A8M1MGA0
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

29088:LOC110587810
gene id: 29088:LOC110587810
uniprot id: A0A2Y9HPK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:MRPL3
gene id: 29088:MRPL3
uniprot id: A0A2Y9G8G9
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

29088:LOC110570949
gene id: 29088:LOC110570949
uniprot id: A0A8M1M6S3
names: Similarity
messages: Belongs to the LRRFIP family.

29088:IPO5
gene id: 29088:IPO5
uniprot id: A0A2Y9HPX0
uniprot id: A0A2Y9HQK3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:ADCY1
gene id: 29088:ADCY1
uniprot id: A0A8M1MQB5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Membrane

29088:SLC41A2
gene id: 29088:SLC41A2
uniprot id: A0A2Y9GVD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

29088:MVB12B
gene id: 29088:MVB12B
uniprot id: A0A2Y9H679
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

29088:PPFIA1
gene id: 29088:PPFIA1
uniprot id: A0A2Y9GTT1
uniprot id: A0A8M1MPA1
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

29088:AWAT2
gene id: 29088:AWAT2
uniprot id: A0A2Y9GBA4
uniprot id: A0A2Y9GFD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane

29088:STAT2
gene id: 29088:STAT2
uniprot id: A0A2Y9GUM7
uniprot id: A0A2Y9H0E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

29088:TYRO3
gene id: 29088:TYRO3
uniprot id: A0A2Y9HHN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

29088:EIF1
gene id: 29088:EIF1
uniprot id: A0A8M1MUX1
names: Similarity
messages: Belongs to the SUI1 family.

29088:LOC110585304
gene id: 29088:LOC110585304
uniprot id: A0A2Y9HHS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:PCSK6
gene id: 29088:PCSK6
uniprot id: A0A2Y9GE37
uniprot id: A0A2Y9GFM4
names: Similarity
messages: Belongs to the peptidase S8 family.

29088:GALK2
gene id: 29088:GALK2
uniprot id: A0A2Y9HCJ7
uniprot id: A0A8M1MM99
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

29088:SNX32
gene id: 29088:SNX32
uniprot id: A0A2Y9GNK5
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

29088:BICD1
gene id: 29088:BICD1
uniprot id: A0A2Y9H3W8
uniprot id: A0A2Y9H3Z1
uniprot id: A0A8M1MAD2
uniprot id: A0A8M1MCP7
names: Similarity
messages: Belongs to the BicD family.

29088:AQR
gene id: 29088:AQR
uniprot id: A0A2Y9HN94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWF11 family.
messages: Identified in the spliceosome C complex. Component of the XAB2 complex, a multimeric protein complex composed of XAB2, PRPF19, AQR, ZNF830, ISY1, and PPIE.
messages: Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
messages: Nucleus

29088:NDEL1
gene id: 29088:NDEL1
uniprot id: A0A2Y9HES1
uniprot id: A0A2Y9HF52
uniprot id: A0A2Y9HL76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: kinetochore
messages: spindle

29088:FFAR2
gene id: 29088:FFAR2
uniprot id: A0A2Y9HXY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:SEMA4D
gene id: 29088:SEMA4D
uniprot id: A0A2Y9HE47
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the semaphorin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:HOXD13
gene id: 29088:HOXD13
uniprot id: A0A2Y9I582
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

29088:PMS2
gene id: 29088:PMS2
uniprot id: A0A2Y9G9W0
uniprot id: A0A2Y9GCI9
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

29088:NUDT4
gene id: 29088:NUDT4
uniprot id: A0A2Y9GUT6
uniprot id: A0A2Y9GUW0
uniprot id: A0A8M1MBR4
uniprot id: A0A8M1MBW5
names: Similarity
messages: Belongs to the Nudix hydrolase family. DIPP subfamily.

29088:LHB
gene id: 29088:LHB
uniprot id: A0A8M1MZF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

29088:ERLIN1
gene id: 29088:ERLIN1
uniprot id: A0A2Y9HWL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the band 7/mec-2 family.
messages: Endoplasmic reticulum membrane
messages: Mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway.
messages: Membrane

29088:F2RL3
gene id: 29088:F2RL3
uniprot id: A0A2Y9GLN3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:CFL1
gene id: 29088:CFL1
uniprot id: A0A2Y9GN91
uniprot id: A0A8M1MNL4
uniprot id: A0A8M1MRV9
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

29088:RPL27A
gene id: 29088:RPL27A
uniprot id: A0A2Y9GQ55
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

29088:TSSK1B
gene id: 29088:TSSK1B
uniprot id: A0A2Y9H4H1
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:CDC42SE1
gene id: 29088:CDC42SE1
uniprot id: A0A2Y9H188
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Interacts with CDC42 (in GTP-bound form). Interacts weakly with RAC1 and not at all with RHOA.
messages: Membrane
messages: Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.
messages: cytoskeleton

29088:PFKFB3
gene id: 29088:PFKFB3
uniprot id: A0A2Y9HL73
uniprot id: A0A2Y9HLB0
uniprot id: A0A8M1MKV8
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

29088:TSPAN6
gene id: 29088:TSPAN6
uniprot id: A0A2Y9HG28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

29088:LOC110582949
gene id: 29088:LOC110582949
uniprot id: A0A2Y9HGA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:HGD
gene id: 29088:HGD
uniprot id: A0A2Y9H8X1
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

29088:LOC110576458
gene id: 29088:LOC110576458
uniprot id: A0A2Y9GPV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:FAM174A
gene id: 29088:FAM174A
uniprot id: A0A2Y9HSV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

29088:LOC123326495
gene id: 29088:LOC123326495
uniprot id: A0A8M1MYH1
names: Similarity
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Monomer.

29088:ACTA1
gene id: 29088:ACTA1
uniprot id: A0A2Y9HE43
uniprot id: A0A8M1MMD5
names: Similarity
messages: Belongs to the actin family.

29088:PRRX2
gene id: 29088:PRRX2
uniprot id: A0A2Y9H6E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL32 family.
messages: Belongs to the paired homeobox family.
messages: Nucleus

29088:SENP1
gene id: 29088:SENP1
uniprot id: A0A2Y9IDL1
names: Similarity
messages: Belongs to the peptidase C48 family.

29088:NOC2L
gene id: 29088:NOC2L
uniprot id: A0A2Y9GIJ1
uniprot id: A0A2Y9GIU0
uniprot id: A0A2Y9GLZ4
uniprot id: A0A2Y9GNT7
names: Similarity
messages: Belongs to the NOC2 family.

29088:ADGRG2
gene id: 29088:ADGRG2
uniprot id: A0A2Y9GJR6
uniprot id: A0A2Y9GJT1
uniprot id: A0A2Y9GJU7
uniprot id: A0A2Y9GJX6
uniprot id: A0A2Y9GK31
uniprot id: A0A2Y9GN88
uniprot id: A0A2Y9GPZ5
uniprot id: A0A2Y9GQ14
uniprot id: A0A2Y9GQ29
names: Subcellular Location Annotation
messages: Membrane

29088:PHKG1
gene id: 29088:PHKG1
uniprot id: A0A2Y9HWP1
uniprot id: A0A2Y9HWW4
uniprot id: A0A2Y9I1S4
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

29088:FUCA1
gene id: 29088:FUCA1
uniprot id: A0A2Y9GPI2
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

29088:SERPIND1
gene id: 29088:SERPIND1
uniprot id: A0A2Y9GW53
names: Similarity
messages: Belongs to the serpin family.

29088:STIM1
gene id: 29088:STIM1
uniprot id: A0A2Y9IG65
uniprot id: A0A8M1MNQ3
uniprot id: A0A8M1MNQ9
uniprot id: A0A8M1MQN2
uniprot id: A0A8M1MS03
uniprot id: A0A8M1MXJ9
uniprot id: A0A8M1MXK2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:CCT5
gene id: 29088:CCT5
uniprot id: A0A2Y9I9J3
uniprot id: A0A8M1MH04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

29088:PKIB
gene id: 29088:PKIB
uniprot id: A0A2Y9HBZ4
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

29088:LOC110578764
gene id: 29088:LOC110578764
uniprot id: A0A8M1M8K6
uniprot id: A0A8M1MAZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

29088:LIMS2
gene id: 29088:LIMS2
uniprot id: A0A8M1M6M6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors.
messages: Cell membrane
messages: Part of the heterotrimeric IPP complex composed of integrin-linked kinase (ILK), LIMS1 or LIMS2, and PARVA.
messages: focal adhesion

29088:S100A10
gene id: 29088:S100A10
uniprot id: A0A2Y9GWH5
uniprot id: A0A2Y9GWS2
uniprot id: A0A2Y9H0V9
names: Function
messages: Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase.

29088:ISM1
gene id: 29088:ISM1
uniprot id: A0A2Y9I465
names: Similarity
messages: Belongs to the isthmin family.

29088:EGFL6
gene id: 29088:EGFL6
uniprot id: A0A8M1M8V5
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LPAR3
gene id: 29088:LPAR3
uniprot id: A0A2Y9H919
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:CASQ2
gene id: 29088:CASQ2
uniprot id: A0A2Y9H7F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

29088:LMBR1L
gene id: 29088:LMBR1L
uniprot id: A0A2Y9I944
uniprot id: A0A8M1MA93
uniprot id: A0A8M1MAH7
uniprot id: A0A8M1ME00
names: Similarity
messages: Belongs to the LIMR family.

29088:SERPINF2
gene id: 29088:SERPINF2
uniprot id: A0A2Y9IC56
uniprot id: A0A2Y9IEV5
names: Similarity
messages: Belongs to the serpin family.

29088:SNX13
gene id: 29088:SNX13
uniprot id: A0A2Y9H7B6
names: Similarity
messages: Belongs to the sorting nexin family.

29088:EME2
gene id: 29088:EME2
uniprot id: A0A8M1MG02
names: Similarity
messages: Belongs to the EME1/MMS4 family.

29088:SORCS1
gene id: 29088:SORCS1
uniprot id: A0A2Y9HUG7
uniprot id: A0A2Y9HUG8
uniprot id: A0A2Y9HZB4
uniprot id: A0A2Y9I0V2
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

29088:MAP2
gene id: 29088:MAP2
uniprot id: A0A2Y9I3G8
uniprot id: A0A2Y9I3P9
uniprot id: A0A2Y9I8B3
uniprot id: A0A8M1M702
uniprot id: A0A8M1M707
uniprot id: A0A8M1M711
uniprot id: A0A8M1M716
uniprot id: A0A8M1M797
uniprot id: A0A8M1M7A1
uniprot id: A0A8M1M7A6
uniprot id: A0A8M1M7B0
uniprot id: A0A8M1M9E6
uniprot id: A0A8M1M9F1
uniprot id: A0A8M1M9F6
uniprot id: A0A8M1M9G1
uniprot id: A0A8M1MAT9
uniprot id: A0A8M1MAU4
uniprot id: A0A8M1MAU8
uniprot id: A0A8M1MAV2
uniprot id: A0A8M1MFA0
uniprot id: A0A8M1MFA5
uniprot id: A0A8M1MFB0
uniprot id: A0A8M1MFB6
names: Subcellular Location Annotation
messages: cytoskeleton

29088:MINPP1
gene id: 29088:MINPP1
uniprot id: A0A2Y9HQ20
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

29088:GSK3A
gene id: 29088:GSK3A
uniprot id: A0A2Y9H892
uniprot id: A0A8M1MVM9
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

29088:LOC110575026
gene id: 29088:LOC110575026
uniprot id: A0A2Y9GK75
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:TSPAN17
gene id: 29088:TSPAN17
uniprot id: A0A2Y9HRV3
uniprot id: A0A2Y9HRV9
uniprot id: A0A2Y9HYC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

29088:SLC9A8
gene id: 29088:SLC9A8
uniprot id: A0A2Y9GQU9
uniprot id: A0A8M1MMG3
uniprot id: A0A8M1MPF5
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

29088:TXLNA
gene id: 29088:TXLNA
uniprot id: A0A2Y9GKW6
names: Similarity
messages: Belongs to the taxilin family.

29088:VGLL3
gene id: 29088:VGLL3
uniprot id: A0A2Y9H5B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.
messages: Nucleus

29088:AQP11
gene id: 29088:AQP11
uniprot id: A0A2Y9I8Y8
uniprot id: A0A8M1MNN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Cell membrane
messages: Membrane

29088:HIF1A
gene id: 29088:HIF1A
uniprot id: A0A2Y9I6M7
uniprot id: A0A8M1MNW5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:LOC110574785
gene id: 29088:LOC110574785
uniprot id: A0A8M1MFW5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

29088:RNASEH2A
gene id: 29088:RNASEH2A
uniprot id: A0A2Y9IB25
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

29088:LOC123323406
gene id: 29088:LOC123323406
uniprot id: A0A2Y9HDM8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:POMGNT2
gene id: 29088:POMGNT2
uniprot id: A0A2Y9G6J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 61 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:DNAH11
gene id: 29088:DNAH11
uniprot id: A0A2Y9H1U8
names: Similarity
messages: Belongs to the dynein heavy chain family.

29088:LOC110573434
gene id: 29088:LOC110573434
uniprot id: A0A2Y9GJG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110584603
gene id: 29088:LOC110584603
uniprot id: A0A2Y9HLH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAM33 family.
messages: Cell membrane

29088:NFYA
gene id: 29088:NFYA
uniprot id: A0A2Y9H7P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

29088:OPHN1
gene id: 29088:OPHN1
uniprot id: A0A2Y9GC93
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Postsynapse
messages: Presynapse
messages: dendrite

29088:LOC110570050
gene id: 29088:LOC110570050
uniprot id: A0A2Y9G3S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

29088:DGKA
gene id: 29088:DGKA
uniprot id: A0A2Y9GUD4
uniprot id: A0A8M1MKD4
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic diacylglycerol kinase family.
messages: Monomer.

29088:DIAPH1
gene id: 29088:DIAPH1
uniprot id: A0A8M1MJ49
names: Similarity
messages: Belongs to the formin homology family. Diaphanous subfamily.

29088:PAMR1
gene id: 29088:PAMR1
uniprot id: A0A2Y9GME4
uniprot id: A0A2Y9GRF2
uniprot id: A0A2Y9GT44
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:FDXR
gene id: 29088:FDXR
uniprot id: A0A2Y9GC37
uniprot id: A0A8M1MTX4
uniprot id: A0A8M1MTX8
uniprot id: A0A8M1MVQ4
uniprot id: A0A8M1MWW3
uniprot id: A0A8M1MZ07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Mitochondrion
messages: Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.

29088:TFCP2L1
gene id: 29088:TFCP2L1
uniprot id: A0A2Y9HIS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

29088:HOXA3
gene id: 29088:HOXA3
uniprot id: A0A2Y9H148
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

29088:LOC110583080
gene id: 29088:LOC110583080
uniprot id: A0A2Y9HGR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

29088:LOC110592778
gene id: 29088:LOC110592778
uniprot id: A0A2Y9I6R6
uniprot id: A0A8M1ME22
uniprot id: A0A8M1ME66
uniprot id: A0A8M1MG78
uniprot id: A0A8M1MG85
uniprot id: A0A8M1MHM3
uniprot id: A0A8M1MMS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

29088:SELE
gene id: 29088:SELE
uniprot id: A0A2Y9GGS0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selectin/LECAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:RDH10
gene id: 29088:RDH10
uniprot id: A0A2Y9GXB9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29088:AMDHD2
gene id: 29088:AMDHD2
uniprot id: A0A2Y9HQA4
uniprot id: A0A8M1MAU5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.
messages: Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.

29088:LOC123325581
gene id: 29088:LOC123325581
uniprot id: A0A8M1MIK3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:EXOC6
gene id: 29088:EXOC6
uniprot id: A0A2Y9I115
uniprot id: A0A8M1MF58
uniprot id: A0A8M1MF88
uniprot id: A0A8M1MHA4
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

29088:SLC31A2
gene id: 29088:SLC31A2
uniprot id: A0A2Y9H6A1
uniprot id: A0A2Y9HCZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

29088:B3GNT8
gene id: 29088:B3GNT8
uniprot id: A0A2Y9HYF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:LOC110580915
gene id: 29088:LOC110580915
uniprot id: A0A2Y9H3T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:LOC110582408
gene id: 29088:LOC110582408
uniprot id: A0A2Y9HFK3
names: Similarity
messages: Belongs to the HTATSF1 family.

29088:SSTR5
gene id: 29088:SSTR5
uniprot id: A0A2Y9HQC5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:PABPC1
gene id: 29088:PABPC1
uniprot id: A0A2Y9H323
uniprot id: A0A2Y9H512
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

29088:PRIM1
gene id: 29088:PRIM1
uniprot id: A0A2Y9GUG8
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

29088:PAX5
gene id: 29088:PAX5
uniprot id: A0A2Y9H5P9
names: Subcellular Location Annotation
messages: Nucleus

29088:DCTN5
gene id: 29088:DCTN5
uniprot id: A0A2Y9GXJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 5 subfamily.
messages: cytoskeleton

29088:PDE10A
gene id: 29088:PDE10A
uniprot id: A0A2Y9HHL0
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

29088:CES1
gene id: 29088:CES1
uniprot id: A0A2Y9I8Q3
uniprot id: A0A2Y9IFV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

29088:SLC30A9
gene id: 29088:SLC30A9
uniprot id: A0A2Y9I0E2
uniprot id: A0A2Y9I6T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Endoplasmic reticulum
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus

29088:LOC110577916
gene id: 29088:LOC110577916
uniprot id: A0A2Y9GV29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation.
messages: Cajal body
messages: Monomer and homodimer. Interacts with COIL (via C-terminus).
messages: nucleoplasm

29088:GSS
gene id: 29088:GSS
uniprot id: A0A2Y9H0C9
uniprot id: A0A2Y9H549
uniprot id: A0A8M1MMC6
uniprot id: A0A8M1MQM5
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

29088:LOC110571152
gene id: 29088:LOC110571152
uniprot id: A0A8M1M9S0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

29088:FAM13A
gene id: 29088:FAM13A
uniprot id: A0A8M1M5J2
names: Similarity
messages: Belongs to the FAM13 family.

29088:LOC110591477
gene id: 29088:LOC110591477
uniprot id: A0A2Y9I2I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

29088:GBE1
gene id: 29088:GBE1
uniprot id: A0A2Y9H0H9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

29088:MED15
gene id: 29088:MED15
uniprot id: A0A2Y9GW65
uniprot id: A0A8M1MVP5
uniprot id: A0A8M1MYQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 15 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

29088:INHBA
gene id: 29088:INHBA
uniprot id: A0A2Y9I6R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

29088:CHRNB1
gene id: 29088:CHRNB1
uniprot id: A0A2Y9HF72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:CTPS1
gene id: 29088:CTPS1
uniprot id: A0A2Y9GJT0
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

29088:HDHD3
gene id: 29088:HDHD3
uniprot id: A0A2Y9HCX9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

29088:SCAMP2
gene id: 29088:SCAMP2
uniprot id: A0A2Y9HCT3
uniprot id: A0A2Y9HIM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

29088:B4GALT3
gene id: 29088:B4GALT3
uniprot id: A0A2Y9GES4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

29088:ELMO1
gene id: 29088:ELMO1
uniprot id: A0A2Y9HZ11
uniprot id: A0A8M1MQK4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

29088:HDC
gene id: 29088:HDC
uniprot id: A0A2Y9HJB6
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

29088:CASKIN2
gene id: 29088:CASKIN2
uniprot id: A0A2Y9GGR6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

29088:GET4
gene id: 29088:GET4
uniprot id: A0A2Y9GAE1
uniprot id: A0A2Y9GCY6
names: Similarity
messages: Belongs to the GET4 family.

29088:LOC110578251
gene id: 29088:LOC110578251
uniprot id: A0A2Y9GW62
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

29088:TMBIM1
gene id: 29088:TMBIM1
uniprot id: A0A2Y9I520
uniprot id: A0A2Y9I9S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

29088:POLR2M
gene id: 29088:POLR2M
uniprot id: A0A2Y9HDA0
uniprot id: A0A8M1MNE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRINL1 family.
messages: Nucleus

29088:IL1RAPL1
gene id: 29088:IL1RAPL1
uniprot id: A0A2Y9G3I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the interleukin-1 receptor family.
messages: Cell membrane
messages: axon
messages: dendrite

29088:ANK3
gene id: 29088:ANK3
uniprot id: A0A2Y9HZ92
uniprot id: A0A8M1MFV2
names: Subcellular Location Annotation
messages: Membrane

29088:NFRKB
gene id: 29088:NFRKB
uniprot id: A0A2Y9HS35
uniprot id: A0A8M1MP47
names: Subcellular Location Annotation
messages: Nucleus

29088:CLDN7
gene id: 29088:CLDN7
uniprot id: A0A2Y9HLB1
uniprot id: A0A8M1MX47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

29088:MRPL18
gene id: 29088:MRPL18
uniprot id: A0A2Y9HBW1
names: Similarity
messages: Belongs to the universal ribosomal protein uL18 family.

29088:LOC110578664
gene id: 29088:LOC110578664
uniprot id: A0A2Y9GXD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

29088:MAP3K7
gene id: 29088:MAP3K7
uniprot id: A0A2Y9HC88
uniprot id: A0A2Y9HCF3
uniprot id: A0A8M1MIB4
uniprot id: A0A8M1MKD6
uniprot id: A0A8M1MSA3
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by pro-inflammatory cytokines and in response to physical and chemical stresses, including osmotic stress, oxidative stress, arsenic and ultraviolet light irradiation. Activated by 'Lys-63'-linked polyubiquitination and by autophosphorylation.
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cytoplasm

29088:LOC110571154
gene id: 29088:LOC110571154
uniprot id: A0A8M1MMI5
names: Subcellular Location Annotation
messages: Membrane

29088:BANF1
gene id: 29088:BANF1
uniprot id: A0A2Y9GPY7
names: Subcellular Location Annotation
messages: Nucleus

29088:APOE
gene id: 29088:APOE
uniprot id: A0A7F3QY86
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

29088:DRAXIN
gene id: 29088:DRAXIN
uniprot id: A0A2Y9GP66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the draxin family.
messages: Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
messages: Interacts with LRP6.
messages: Secreted

29088:PDGFD
gene id: 29088:PDGFD
uniprot id: A0A8M1MN76
uniprot id: A0A8M1MQ57
names: Caution
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:PARN
gene id: 29088:PARN
uniprot id: A0A2Y9HQF9
uniprot id: A0A8M1MCN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Cytoplasm

29088:RETREG1
gene id: 29088:RETREG1
uniprot id: A0A2Y9I365
uniprot id: A0A2Y9I7K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RETREG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:INTS10
gene id: 29088:INTS10
uniprot id: A0A2Y9GDY2
uniprot id: A0A8M1M377
uniprot id: A0A8M1M3H1
uniprot id: A0A8M1M768
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 10 family.
messages: Nucleus

29088:ZPR1
gene id: 29088:ZPR1
uniprot id: A0A2Y9HJX0
uniprot id: A0A8M1MN60
names: Similarity
messages: Belongs to the ZPR1 family.

29088:LOC110582670
gene id: 29088:LOC110582670
uniprot id: A0A8M1MRG1
names: Similarity
messages: Belongs to the FAM149 family.

29088:TLR1
gene id: 29088:TLR1
uniprot id: A0A2Y9I0H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane
messages: Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.

29088:GOSR1
gene id: 29088:GOSR1
uniprot id: A0A2Y9I709
uniprot id: A0A2Y9IBF8
uniprot id: A0A2Y9IE36
uniprot id: A0A8M1MWY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
messages: Membrane

29088:PLD1
gene id: 29088:PLD1
uniprot id: A0A2Y9I3A3
uniprot id: A0A2Y9I3K1
uniprot id: A0A2Y9I7W3
uniprot id: A0A2Y9IA16
uniprot id: A0A8M1MYA9
names: Similarity
messages: Belongs to the phospholipase D family.

29088:LOC110577482
gene id: 29088:LOC110577482
uniprot id: A0A2Y9GT63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:MOCS1
gene id: 29088:MOCS1
uniprot id: A0A2Y9H7S5
uniprot id: A0A8M1MHG2
names: Similarity
messages: In the C-terminal section; belongs to the MoaC family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. MoaA family.

29088:SLC2A2
gene id: 29088:SLC2A2
uniprot id: A0A2Y9I2S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Membrane

29088:ARAP2
gene id: 29088:ARAP2
uniprot id: A0A8M1M509
names: Subcellular Location Annotation
messages: Cytoplasm

29088:LOC110590162
gene id: 29088:LOC110590162
uniprot id: A0A2Y9HY23
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

29088:LOC110575784
gene id: 29088:LOC110575784
uniprot id: A0A2Y9GTC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LCN15
gene id: 29088:LCN15
uniprot id: A0A8M1MRZ7
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

29088:BARX2
gene id: 29088:BARX2
uniprot id: A0A2Y9HJG8
names: Subcellular Location Annotation
messages: Nucleus

29088:ALDOB
gene id: 29088:ALDOB
uniprot id: A0A2Y9HCW4
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

29088:CNOT1
gene id: 29088:CNOT1
uniprot id: A0A2Y9IBS3
uniprot id: A0A2Y9IBS9
uniprot id: A0A2Y9IBX6
uniprot id: A0A2Y9IBY5
uniprot id: A0A2Y9ICM5
uniprot id: A0A2Y9IG78
uniprot id: A0A2Y9IG83
uniprot id: A0A2Y9IJB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT1 family.
messages: Nucleus

29088:LOC110584080
gene id: 29088:LOC110584080
uniprot id: A0A8M1MDJ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion intermembrane space

29088:PREB
gene id: 29088:PREB
uniprot id: A0A2Y9HN14
uniprot id: A0A2Y9HNH6
uniprot id: A0A8M1MPL8
uniprot id: A0A8M1MVH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat SEC12 family.
messages: Endoplasmic reticulum membrane
messages: Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitment of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore required for the formation of COPII transport vesicles from the ER.
messages: Interacts with SAR1B (GDP-bound form). Interacts with MIA2; recruits PREB to endoplasmic reticulum exit sites.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Was first identified based on its probable role in the regulation of pituitary gene transcription. Binds to the prolactin gene (PRL) promoter and seems to activate transcription.

29088:WAPL
gene id: 29088:WAPL
uniprot id: A0A2Y9HUX4
uniprot id: A0A2Y9HVH6
uniprot id: A0A2Y9I094
names: Similarity
messages: Belongs to the WAPL family.

29088:LOC110593144
gene id: 29088:LOC110593144
uniprot id: A0A8M1MWV4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:HOXD3
gene id: 29088:HOXD3
uniprot id: A0A2Y9I9F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

29088:PCSK2
gene id: 29088:PCSK2
uniprot id: A0A8M1MLA4
uniprot id: A0A8M1MPK8
names: Similarity
messages: Belongs to the peptidase S8 family.

29088:LOC110589222
gene id: 29088:LOC110589222
uniprot id: A0A8M1MS57
names: Similarity
messages: Belongs to the CBF/MAK21 family.

29088:BOLA3
gene id: 29088:BOLA3
uniprot id: A0A2Y9HYA3
names: Similarity
messages: Belongs to the BolA/IbaG family.

29088:ADORA1
gene id: 29088:ADORA1
uniprot id: A0A2Y9GSN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

29088:LOC123325710
gene id: 29088:LOC123325710
uniprot id: A0A8M1MNB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:CNIH1
gene id: 29088:CNIH1
uniprot id: A0A2Y9I621
uniprot id: A0A8M1MIV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

29088:CFAP299
gene id: 29088:CFAP299
uniprot id: A0A2Y9I778
uniprot id: A0A8M1M6I8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in spermatogenesis.
messages: Nucleus

29088:BBOX1
gene id: 29088:BBOX1
uniprot id: A0A2Y9GUS2
names: Function
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.
messages: Catalyzes the formation of L-carnitine from gamma-butyrobetaine.

29088:STK17A
gene id: 29088:STK17A
uniprot id: A0A2Y9IAP5
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:ZBED9
gene id: 29088:ZBED9
uniprot id: A0A2Y9HMC3
names: Subcellular Location Annotation
messages: Nucleus

29088:AMZ1
gene id: 29088:AMZ1
uniprot id: A0A2Y9GCL0
uniprot id: A0A8M1MDI0
names: Function
names: Similarity
messages: Belongs to the peptidase M54 family.
messages: Probable zinc metalloprotease.

29088:GPR107
gene id: 29088:GPR107
uniprot id: A0A2Y9HC46
uniprot id: A0A8M1MYF4
names: Subcellular Location Annotation
messages: Membrane

29088:MED12L
gene id: 29088:MED12L
uniprot id: A0A2Y9GR18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 12 family.
messages: Nucleus

29088:SCN3B
gene id: 29088:SCN3B
uniprot id: A0A2Y9HRZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.
messages: Membrane
messages: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.

29088:LOC110591111
gene id: 29088:LOC110591111
uniprot id: A0A2Y9I170
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:DARS1
gene id: 29088:DARS1
uniprot id: A0A2Y9HI89
uniprot id: A0A2Y9HIN7
uniprot id: A0A2Y9HPC8
names: Function
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.

29088:GABRA1
gene id: 29088:GABRA1
uniprot id: A0A2Y9HWG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:LOC110583352
gene id: 29088:LOC110583352
uniprot id: A0A8M1MHP5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Interacts with PPIF; the interaction is impaired by CsA.
messages: Membrane
messages: Mitochondrion inner membrane

29088:ATP13A2
gene id: 29088:ATP13A2
uniprot id: A0A8M1M7I2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:AHCYL1
gene id: 29088:AHCYL1
uniprot id: A0A2Y9H7U7
uniprot id: A0A2Y9H9G7
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

29088:LOC110582774
gene id: 29088:LOC110582774
uniprot id: A0A2Y9H9Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

29088:ZNF280D
gene id: 29088:ZNF280D
uniprot id: A0A2Y9HCV5
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor.
messages: Nucleus

29088:FGF16
gene id: 29088:FGF16
uniprot id: A0A2Y9GWL2
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

29088:CHAF1B
gene id: 29088:CHAF1B
uniprot id: A0A2Y9G463
names: Subcellular Location Annotation
messages: Nucleus

29088:FAM118A
gene id: 29088:FAM118A
uniprot id: A0A2Y9GW66
uniprot id: A0A2Y9H0B8
names: Similarity
messages: Belongs to the FAM118 family.

29088:APLP2
gene id: 29088:APLP2
uniprot id: A0A2Y9HS01
uniprot id: A0A8M1MQD8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:IKBKB
gene id: 29088:IKBKB
uniprot id: A0A2Y9GDW5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:MMP11
gene id: 29088:MMP11
uniprot id: A0A2Y9GWM4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

29088:LOC110574333
gene id: 29088:LOC110574333
uniprot id: A0A8M1M8N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

29088:GALNT17
gene id: 29088:GALNT17
uniprot id: A0A2Y9HX11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

29088:PUS7
gene id: 29088:PUS7
uniprot id: A0A2Y9GHH7
uniprot id: A0A8M1MRT1
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

29088:LOC110573550
gene id: 29088:LOC110573550
uniprot id: A0A2Y9GFB9
uniprot id: A0A2Y9GK04
uniprot id: A0A8M1MD73
uniprot id: A0A8M1MDC3
uniprot id: A0A8M1MFE0
uniprot id: A0A8M1MGT7
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

29088:LOC110575301
gene id: 29088:LOC110575301
uniprot id: A0A2Y9GQ82
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

29088:HOOK3
gene id: 29088:HOOK3
uniprot id: A0A2Y9GE22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

29088:FABP7
gene id: 29088:FABP7
uniprot id: A0A2Y9HHH6
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Belongs to the calycin superfamily. Lipocalin family.

29088:CCDC22
gene id: 29088:CCDC22
uniprot id: A0A8M1M1E0
uniprot id: A0A8M1M3X2
names: Similarity
messages: Belongs to the CCDC22 family.

29088:PPOX
gene id: 29088:PPOX
uniprot id: A0A2Y9GEM9
uniprot id: A0A2Y9GES6
uniprot id: A0A2Y9GES8
uniprot id: A0A2Y9GHV3
uniprot id: A0A2Y9GJB4
uniprot id: A0A2Y9GJB7
uniprot id: A0A8M1MGK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
messages: Mitochondrion inner membrane

29088:CBLIF
gene id: 29088:CBLIF
uniprot id: A0A8M1MXN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic cobalamin transport proteins family.
messages: Secreted

29088:SH2B1
gene id: 29088:SH2B1
uniprot id: A0A8M1MAY7
uniprot id: A0A8M1MB67
uniprot id: A0A8M1MD97
uniprot id: A0A8M1MJH2
names: Similarity
messages: Belongs to the SH2B adapter family.

29088:FABP4
gene id: 29088:FABP4
uniprot id: A0A2Y9H4Y0
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Belongs to the calycin superfamily. Lipocalin family.

29088:MAPK9
gene id: 29088:MAPK9
uniprot id: A0A8M1MPJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

29088:LOC110572000
gene id: 29088:LOC110572000
uniprot id: A0A8M1MGF7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

29088:S100A4
gene id: 29088:S100A4
uniprot id: A0A2Y9GF60
names: Similarity
messages: Belongs to the S-100 family.

29088:IFT20
gene id: 29088:IFT20
uniprot id: A0A2Y9I8S4
uniprot id: A0A8M1MWQ3
uniprot id: A0A8M1MXI8
names: Subcellular Location Annotation
messages: centriole
messages: cilium
messages: cis-Golgi network

29088:GOLT1A
gene id: 29088:GOLT1A
uniprot id: A0A2Y9GSP6
uniprot id: A0A2Y9GSU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

29088:INPP5J
gene id: 29088:INPP5J
uniprot id: A0A2Y9I566
uniprot id: A0A2Y9I5C3
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.

29088:ATL1
gene id: 29088:ATL1
uniprot id: A0A8M1MMV9
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

29088:HSP90AB1
gene id: 29088:HSP90AB1
uniprot id: A0A2Y9H7F4
uniprot id: A0A8M1MLX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 90 family.
messages: Melanosome

29088:C5AR2
gene id: 29088:C5AR2
uniprot id: A0A2Y9GCY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

29088:LOC110580611
gene id: 29088:LOC110580611
uniprot id: A0A8M1M916
names: Similarity
messages: Belongs to the PDCD5 family.

29088:BLOC1S2
gene id: 29088:BLOC1S2
uniprot id: A0A2Y9HV19
uniprot id: A0A8M1MHD1
names: Similarity
messages: Belongs to the BLOC1S2 family.

29088:PATJ
gene id: 29088:PATJ
uniprot id: A0A8M1MHS2
names: Subcellular Location Annotation
messages: Cell membrane
messages: tight junction

29088:SRRT
gene id: 29088:SRRT
uniprot id: A0A2Y9GA12
uniprot id: A0A2Y9GA38
uniprot id: A0A2Y9GA56
uniprot id: A0A2Y9GDV8
names: Similarity
messages: Belongs to the ARS2 family.

29088:LOC110570269
gene id: 29088:LOC110570269
uniprot id: A0A2Y9G4G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I) and RNA polymerase III (Pol III) complexes consisting of at least 13 and 17 subunits, respectively.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively.

29088:RAB3GAP2
gene id: 29088:RAB3GAP2
uniprot id: A0A8M1MDA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab3-GAP regulatory subunit family.
messages: Cytoplasm

29088:SLC45A4
gene id: 29088:SLC45A4
uniprot id: A0A2Y9GY76
uniprot id: A0A2Y9H4H8
names: Subcellular Location Annotation
messages: Membrane

29088:FER1L5
gene id: 29088:FER1L5
uniprot id: A0A2Y9HYX3
names: Similarity
messages: Belongs to the ferlin family.

29088:CHMP6
gene id: 29088:CHMP6
uniprot id: A0A2Y9GBQ2
uniprot id: A0A2Y9GBX6
names: Similarity
messages: Belongs to the SNF7 family.

29088:SLC25A26
gene id: 29088:SLC25A26
uniprot id: A0A2Y9HFZ9
uniprot id: A0A2Y9HGF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:TRMT112
gene id: 29088:TRMT112
uniprot id: A0A2Y9GPQ0
uniprot id: A0A8M1MPM0
names: Similarity
messages: Belongs to the TRM112 family.

29088:RBM47
gene id: 29088:RBM47
uniprot id: A0A2Y9I4Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM RBM47 family.
messages: Cytoplasm
messages: Nucleus

29088:SEPTIN7
gene id: 29088:SEPTIN7
uniprot id: A0A2Y9HTN9
uniprot id: A0A2Y9HU76
uniprot id: A0A2Y9HU77
uniprot id: A0A2Y9HZ31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Filament-forming cytoskeletal GTPase.
messages: Midbody
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.
messages: cilium axoneme
messages: flagellum
messages: kinetochore
messages: spindle

29088:HOXB5
gene id: 29088:HOXB5
uniprot id: A0A2Y9I6Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

29088:PRDM13
gene id: 29088:PRDM13
uniprot id: A0A2Y9HI27
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110577799
gene id: 29088:LOC110577799
uniprot id: A0A2Y9GUD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:XRCC6
gene id: 29088:XRCC6
uniprot id: A0A2Y9GUZ7
uniprot id: A0A2Y9GV90
uniprot id: A0A2Y9GZ86
uniprot id: A0A8M1MBM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku70 family.
messages: Nucleus

29088:LBH
gene id: 29088:LBH
uniprot id: A0A2Y9HTH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LBH family.
messages: Cytoplasm
messages: Nucleus
messages: Transcriptional activator.

29088:SLC20A2
gene id: 29088:SLC20A2
uniprot id: A0A2Y9GID0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

29088:CNNM3
gene id: 29088:CNNM3
uniprot id: A0A8M1MWG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Cell membrane
messages: Membrane
messages: Metal transporter.

29088:LOC110589700
gene id: 29088:LOC110589700
uniprot id: A0A2Y9I2Y8
names: Similarity
messages: Belongs to the histone H2B family.

29088:XKR7
gene id: 29088:XKR7
uniprot id: A0A2Y9H6J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

29088:SPSB2
gene id: 29088:SPSB2
uniprot id: A0A2Y9H495
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

29088:LOC110590011
gene id: 29088:LOC110590011
uniprot id: A0A8M1MNL1
names: Similarity
messages: Belongs to the ATG8 family.

29088:LOC110583457
gene id: 29088:LOC110583457
uniprot id: A0A2Y9HBW6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:TAS2R4
gene id: 29088:TAS2R4
uniprot id: A0A2Y9HA86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

29088:YPEL4
gene id: 29088:YPEL4
uniprot id: A0A2Y9GTF9
names: Similarity
messages: Belongs to the yippee family.

29088:LRP2
gene id: 29088:LRP2
uniprot id: A0A2Y9IAH7
names: Caution
names: Similarity
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:STX19
gene id: 29088:STX19
uniprot id: A0A2Y9H2V0
names: Similarity
messages: Belongs to the syntaxin family.

29088:RHOT1
gene id: 29088:RHOT1
uniprot id: A0A2Y9I825
uniprot id: A0A2Y9I8C8
uniprot id: A0A2Y9ICS1
uniprot id: A0A2Y9IFI0
uniprot id: A0A8M1MUZ0
uniprot id: A0A8M1MWQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

29088:HSPA2
gene id: 29088:HSPA2
uniprot id: A0A2Y9I432
names: Similarity
messages: Belongs to the heat shock protein 70 family.

29088:TPX2
gene id: 29088:TPX2
uniprot id: A0A8M1ML79
uniprot id: A0A8M1MN85
uniprot id: A0A8M1MVD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPX2 family.
messages: Nucleus
messages: spindle pole

29088:RIDA
gene id: 29088:RIDA
uniprot id: A0A2Y9GXJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RutC family.
messages: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.
messages: Peroxisome

29088:PIGS
gene id: 29088:PIGS
uniprot id: A0A2Y9IBQ6
uniprot id: A0A2Y9IEE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:LOC110585870
gene id: 29088:LOC110585870
uniprot id: A0A8M1MJU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

29088:SLC29A3
gene id: 29088:SLC29A3
uniprot id: A0A8M1MEA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

29088:SSRP1
gene id: 29088:SSRP1
uniprot id: A0A2Y9GTE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Nucleus

29088:MEIG1
gene id: 29088:MEIG1
uniprot id: A0A2Y9HL89
names: Function
names: Similarity
messages: Belongs to the MEIG1 family.
messages: Essential for spermiogenesis.

29088:PRDM6
gene id: 29088:PRDM6
uniprot id: A0A2Y9I614
names: Subcellular Location Annotation
messages: Nucleus

29088:ASXL2
gene id: 29088:ASXL2
uniprot id: A0A2Y9HT96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asx family.
messages: Nucleus

29088:C7
gene id: 29088:C7
uniprot id: A0A2Y9HK94
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:CMKLR2
gene id: 29088:CMKLR2
uniprot id: A0A2Y9I4J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

29088:NSG2
gene id: 29088:NSG2
uniprot id: A0A2Y9HXQ6
names: Similarity
messages: Belongs to the NSG family.

29088:C11H11orf68
gene id: 29088:C11H11orf68
uniprot id: A0A2Y9GP43
names: Similarity
messages: Belongs to the UPF0696 family.

29088:CLUAP1
gene id: 29088:CLUAP1
uniprot id: A0A2Y9HPT0
uniprot id: A0A8M1MCK3
uniprot id: A0A8M1MG20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLUAP1 family.
messages: cilium

29088:SOD2
gene id: 29088:SOD2
uniprot id: A0A2Y9HAS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homotetramer.
messages: Mitochondrion matrix

29088:LOC110581275
gene id: 29088:LOC110581275
uniprot id: A0A8M1MRA1
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

29088:ANO2
gene id: 29088:ANO2
uniprot id: A0A2Y9H3T0
uniprot id: A0A2Y9H912
uniprot id: A0A8M1MEC2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:SUPT3H
gene id: 29088:SUPT3H
uniprot id: A0A2Y9HE68
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110589382
gene id: 29088:LOC110589382
uniprot id: A0A8M1MHQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

29088:LOC110573097
gene id: 29088:LOC110573097
uniprot id: A0A2Y9GDP1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ABCB5
gene id: 29088:ABCB5
uniprot id: A0A2Y9H7Q8
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110575532
gene id: 29088:LOC110575532
uniprot id: A0A2Y9GM50
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110585527
gene id: 29088:LOC110585527
uniprot id: A0A2Y9HIB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110588531
gene id: 29088:LOC110588531
uniprot id: A0A8M1M4I6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).
messages: Nucleus

29088:CCDC103
gene id: 29088:CCDC103
uniprot id: A0A2Y9GDZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC103/PR46b family.
messages: Cytoplasm
messages: Dynein-attachment factor required for cilia motility.
messages: Homodimer.
messages: flagellum

29088:KCNG3
gene id: 29088:KCNG3
uniprot id: A0A2Y9HNP6
uniprot id: A0A2Y9HVC5
names: Subcellular Location Annotation
messages: Membrane

29088:B4GALNT4
gene id: 29088:B4GALNT4
uniprot id: A0A2Y9HEX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

29088:SSR2
gene id: 29088:SSR2
uniprot id: A0A2Y9GEU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-beta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

29088:ABCG8
gene id: 29088:ABCG8
uniprot id: A0A2Y9HYW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

29088:HCFC1
gene id: 29088:HCFC1
uniprot id: A0A8M1M571
uniprot id: A0A8M1M8Y1
names: Subcellular Location Annotation
messages: Nucleus

29088:ACMSD
gene id: 29088:ACMSD
uniprot id: A0A2Y9HIE1
uniprot id: A0A2Y9HPG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
messages: Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
messages: Monomer.

29088:ADAMTS18
gene id: 29088:ADAMTS18
uniprot id: A0A2Y9I3Y2
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:EDEM3
gene id: 29088:EDEM3
uniprot id: A0A2Y9GLK2
uniprot id: A0A8M1MGU5
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

29088:DAND5
gene id: 29088:DAND5
uniprot id: A0A2Y9IFN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

29088:LOC110593295
gene id: 29088:LOC110593295
uniprot id: A0A2Y9I927
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

29088:PDX1
gene id: 29088:PDX1
uniprot id: A0A2Y9G702
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

29088:GNG2
gene id: 29088:GNG2
uniprot id: A0A2Y9HZR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

29088:HEBP2
gene id: 29088:HEBP2
uniprot id: A0A2Y9HHN7
uniprot id: A0A8M1MHU0
names: Similarity
messages: Belongs to the HEBP family.

29088:SLC39A14
gene id: 29088:SLC39A14
uniprot id: A0A2Y9HX41
names: Subcellular Location Annotation
messages: Membrane

29088:TBX18
gene id: 29088:TBX18
uniprot id: A0A2Y9HIE3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

29088:LOC110576459
gene id: 29088:LOC110576459
uniprot id: A0A8M1MPC8
names: Subcellular Location Annotation
messages: Membrane

29088:HTR7
gene id: 29088:HTR7
uniprot id: A0A2Y9I035
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:LOC110578952
gene id: 29088:LOC110578952
uniprot id: A0A2Y9GY62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

29088:KIF1B
gene id: 29088:KIF1B
uniprot id: A0A8M1M955
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: axon

29088:RAP2C
gene id: 29088:RAP2C
uniprot id: A0A2Y9GPZ3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Palmitoylated.
messages: Recycling endosome membrane
messages: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form.

29088:GPT2
gene id: 29088:GPT2
uniprot id: A0A2Y9IJI3
uniprot id: A0A8M1MVY2
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

29088:EMX2
gene id: 29088:EMX2
uniprot id: A0A2Y9HVT6
names: Subcellular Location Annotation
messages: Nucleus

29088:ADCYAP1R1
gene id: 29088:ADCYAP1R1
uniprot id: A0A2Y9H152
uniprot id: A0A2Y9H199
uniprot id: A0A2Y9H1B4
uniprot id: A0A2Y9H7Q1
names: Subcellular Location Annotation
messages: Membrane

29088:GPR137B
gene id: 29088:GPR137B
uniprot id: A0A8M1MDL8
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

29088:CA14
gene id: 29088:CA14
uniprot id: A0A2Y9H121
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

29088:PDCL2
gene id: 29088:PDCL2
uniprot id: A0A2Y9I554
names: Similarity
messages: Belongs to the phosducin family.

29088:KIF12
gene id: 29088:KIF12
uniprot id: A0A2Y9HD38
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:PPP6R2
gene id: 29088:PPP6R2
uniprot id: A0A2Y9GVA5
uniprot id: A0A2Y9H159
uniprot id: A0A8M1MBL1
uniprot id: A0A8M1MDU7
uniprot id: A0A8M1MF85
uniprot id: A0A8M1MK43
names: Similarity
messages: Belongs to the SAPS family.

29088:WEE1
gene id: 29088:WEE1
uniprot id: A0A2Y9GW01
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

29088:MSN
gene id: 29088:MSN
uniprot id: A0A2Y9GB75
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton
messages: microvillus

29088:RALYL
gene id: 29088:RALYL
uniprot id: A0A2Y9H3M2
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

29088:OSTC
gene id: 29088:OSTC
uniprot id: A0A2Y9GLS3
uniprot id: A0A8M1MBX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OSTC family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. May be involved in N-glycosylation of APP (amyloid-beta precursor protein). Can modulate gamma-secretase cleavage of APP by enhancing endoprotelysis of PSEN1.

29088:CDO1
gene id: 29088:CDO1
uniprot id: A0A2Y9I1T5
uniprot id: A0A8M1MK61
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen.

29088:PTGER2
gene id: 29088:PTGER2
uniprot id: A0A2Y9I028
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:CRYAA
gene id: 29088:CRYAA
uniprot id: A0A2Y9G7B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Contributes to the transparency and refractive index of the lens. Acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
messages: Cytoplasm
messages: Heteromer composed of three CRYAA and one CRYAB subunits. Inter-subunit bridging via zinc ions enhances stability, which is crucial as there is no protein turn over in the lens. Can also form homodimers and homotetramers (dimers of dimers) which serve as the building blocks of homooligomers (By similarity). Within homooligomers, the zinc-binding motif is created from residues of 3 different molecules. His-100 and Glu-102 from one molecule are ligands of the zinc ion, and His-107 and His-154 residues from additional molecules complete the site with tetrahedral coordination geometry (By similarity). Part of a complex required for lens intermediate filament formation composed of BFSP1, BFSP2 and CRYAA.
messages: May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
messages: Nucleus

29088:FAM161A
gene id: 29088:FAM161A
uniprot id: A0A2Y9HSY3
uniprot id: A0A2Y9HTF0
names: Similarity
messages: Belongs to the FAM161 family.

29088:DNPH1
gene id: 29088:DNPH1
uniprot id: A0A2Y9HE95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family.
messages: Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer.
messages: Nucleus

29088:LMX1B
gene id: 29088:LMX1B
uniprot id: A0A2Y9H6M9
uniprot id: A0A2Y9H6N1
uniprot id: A0A2Y9H6T0
names: Subcellular Location Annotation
messages: Nucleus

29088:TNFRSF1A
gene id: 29088:TNFRSF1A
uniprot id: A0A2Y9H3L6
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:LOC110590091
gene id: 29088:LOC110590091
uniprot id: A0A2Y9HY33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

29088:AKAP8
gene id: 29088:AKAP8
uniprot id: A0A2Y9GIJ3
uniprot id: A0A2Y9GIR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AKAP95 family.
messages: Nucleus matrix

29088:LOC110582181
gene id: 29088:LOC110582181
uniprot id: A0A8M1MIA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

29088:RDX
gene id: 29088:RDX
uniprot id: A0A2Y9HKR7
uniprot id: A0A8M1MPB2
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton
messages: microvillus

29088:C14H22orf39
gene id: 29088:C14H22orf39
uniprot id: A0A2Y9H4K1
uniprot id: A0A8M1MV70
names: Similarity
messages: Belongs to the UPF0545 family.

29088:CAMSAP3
gene id: 29088:CAMSAP3
uniprot id: A0A8M1M957
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

29088:NLRP3
gene id: 29088:NLRP3
uniprot id: A0A2Y9H6V4
names: Similarity
messages: Belongs to the NLRP family.

29088:ACTL6A
gene id: 29088:ACTL6A
uniprot id: A0A2Y9H8F2
uniprot id: A0A2Y9HE58
uniprot id: A0A2Y9HF79
names: Similarity
messages: Belongs to the actin family.

29088:RPS17
gene id: 29088:RPS17
uniprot id: A0A2Y9GBJ2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

29088:LOC110590216
gene id: 29088:LOC110590216
uniprot id: A0A2Y9HY78
names: Similarity
messages: Belongs to the GAGE family.

29088:NRDE2
gene id: 29088:NRDE2
uniprot id: A0A2Y9G8Z8
names: Similarity
messages: Belongs to the NRDE2 family.

29088:ADGRG7
gene id: 29088:ADGRG7
uniprot id: A0A2Y9HFV8
names: Subcellular Location Annotation
messages: Membrane

29088:KCNE4
gene id: 29088:KCNE4
uniprot id: A0A2Y9IC21
names: Similarity
messages: Belongs to the potassium channel KCNE family.

29088:AMD1
gene id: 29088:AMD1
uniprot id: A0A2Y9HH87
uniprot id: A0A8M1MHK0
uniprot id: A0A8M1MJN0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.
messages: Heterotetramer of two alpha and two beta chains.

29088:LOC110576070
gene id: 29088:LOC110576070
uniprot id: A0A2Y9GNK2
uniprot id: A0A2Y9GNM9
uniprot id: A0A2Y9GNW0
uniprot id: A0A2Y9GSL4
uniprot id: A0A2Y9GUA8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:SCML4
gene id: 29088:SCML4
uniprot id: A0A2Y9HBR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

29088:CD82
gene id: 29088:CD82
uniprot id: A0A2Y9GMG1
uniprot id: A0A2Y9GRH8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:LOC110576676
gene id: 29088:LOC110576676
uniprot id: A0A8M1MXM1
names: Similarity
messages: Belongs to the cyclin family.

29088:LOC110590065
gene id: 29088:LOC110590065
uniprot id: A0A8M1MWL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
messages: Forms a heterodimer with PSMG1.

29088:LOC110581750
gene id: 29088:LOC110581750
uniprot id: A0A2Y9H6M6
uniprot id: A0A2Y9H6S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly.
messages: Mitochondrion inner membrane

29088:PEX5
gene id: 29088:PEX5
uniprot id: A0A2Y9H4E0
uniprot id: A0A2Y9H4F9
uniprot id: A0A2Y9H9S7
uniprot id: A0A2Y9HB35
uniprot id: A0A8M1MAI0
names: Similarity
messages: Belongs to the peroxisomal targeting signal receptor family.

29088:GLRX
gene id: 29088:GLRX
uniprot id: A0A2Y9I0I6
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

29088:SEC61A1
gene id: 29088:SEC61A1
uniprot id: A0A2Y9HM42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:JAK3
gene id: 29088:JAK3
uniprot id: A0A2Y9GN84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system

29088:LOC110583597
gene id: 29088:LOC110583597
uniprot id: A0A2Y9HBY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

29088:TIMM8B
gene id: 29088:TIMM8B
uniprot id: A0A2Y9HS25
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

29088:LOC110592074
gene id: 29088:LOC110592074
uniprot id: A0A2Y9I444
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

29088:SOX21
gene id: 29088:SOX21
uniprot id: A0A2Y9HIN4
uniprot id: A0A8M1M5N9
names: Subcellular Location Annotation
messages: Nucleus

29088:PUS10
gene id: 29088:PUS10
uniprot id: A0A8M1MMZ0
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.

29088:RPL3L
gene id: 29088:RPL3L
uniprot id: A0A2Y9HWE1
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

29088:LOC110575420
gene id: 29088:LOC110575420
uniprot id: A0A8M1MFM5
names: Similarity
messages: Belongs to the TGF-beta family.

29088:PLAU
gene id: 29088:PLAU
uniprot id: A0A2Y9HUG2
uniprot id: A0A8M1MII7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110586371
gene id: 29088:LOC110586371
uniprot id: A0A2Y9HKI0
uniprot id: A0A2Y9HKS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

29088:RBBP4
gene id: 29088:RBBP4
uniprot id: A0A2Y9GJK2
uniprot id: A0A8M1M7P1
names: Subcellular Location Annotation
messages: Nucleus

29088:ADGRL3
gene id: 29088:ADGRL3
uniprot id: A0A8M1M4T0
uniprot id: A0A8M1M4T6
uniprot id: A0A8M1M534
uniprot id: A0A8M1M538
uniprot id: A0A8M1M781
uniprot id: A0A8M1M785
uniprot id: A0A8M1M8Q1
uniprot id: A0A8M1M8Q6
uniprot id: A0A8M1MCV5
uniprot id: A0A8M1MCW1
names: Subcellular Location Annotation
messages: Membrane

29088:HAL
gene id: 29088:HAL
uniprot id: A0A2Y9GUU4
names: Similarity
messages: Belongs to the PAL/histidase family.

29088:MTHFR
gene id: 29088:MTHFR
uniprot id: A0A2Y9GJ70
uniprot id: A0A8M1M9W4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

29088:LOC110573353
gene id: 29088:LOC110573353
uniprot id: A0A2Y9GEK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ADAMTS2
gene id: 29088:ADAMTS2
uniprot id: A0A8M1MFI3
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:HTRA3
gene id: 29088:HTRA3
uniprot id: A0A2Y9G399
names: Similarity
messages: Belongs to the peptidase S1C family.

29088:LOC110576533
gene id: 29088:LOC110576533
uniprot id: A0A2Y9GQ98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ARID1A
gene id: 29088:ARID1A
uniprot id: A0A2Y9GR74
names: Subcellular Location Annotation
messages: Nucleus

29088:LGI2
gene id: 29088:LGI2
uniprot id: A0A2Y9G7T3
names: Subcellular Location Annotation
messages: Secreted

29088:NLGN3
gene id: 29088:NLGN3
uniprot id: A0A2Y9GEZ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:PLA2G3
gene id: 29088:PLA2G3
uniprot id: A0A2Y9IA18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Secreted

29088:NMNAT1
gene id: 29088:NMNAT1
uniprot id: A0A2Y9GMG2
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

29088:HMGCR
gene id: 29088:HMGCR
uniprot id: A0A2Y9I1K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane

29088:TUBAL3
gene id: 29088:TUBAL3
uniprot id: A0A8M1MCB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

29088:FABP5
gene id: 29088:FABP5
uniprot id: A0A2Y9H3L7
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Belongs to the calycin superfamily. Lipocalin family.

29088:UPF2
gene id: 29088:UPF2
uniprot id: A0A2Y9HL29
uniprot id: A0A2Y9HSL9
names: Subcellular Location Annotation
messages: Cytoplasm

29088:ATG4A
gene id: 29088:ATG4A
uniprot id: A0A2Y9G5B7
uniprot id: A0A8M1M9I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

29088:MAPK13
gene id: 29088:MAPK13
uniprot id: A0A2Y9GM67
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Interacts with MAPK8IP2.

29088:ETV1
gene id: 29088:ETV1
uniprot id: A0A2Y9H117
uniprot id: A0A2Y9H170
uniprot id: A0A2Y9H182
uniprot id: A0A2Y9H5W5
uniprot id: A0A8M1MPW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

29088:LYPD2
gene id: 29088:LYPD2
uniprot id: A0A2Y9H3L3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:HNRNPF
gene id: 29088:HNRNPF
uniprot id: A0A2Y9HW08
uniprot id: A0A8M1MHG4
names: Subcellular Location Annotation
messages: nucleoplasm

29088:BRIP1
gene id: 29088:BRIP1
uniprot id: A0A8M1MZ98
names: Similarity
messages: Belongs to the RTRAF family.

29088:CTNNA3
gene id: 29088:CTNNA3
uniprot id: A0A2Y9HVN5
names: Similarity
messages: Belongs to the vinculin/alpha-catenin family.

29088:UBALD1
gene id: 29088:UBALD1
uniprot id: A0A2Y9HVE4
uniprot id: A0A8M1MCL2
names: Similarity
messages: Belongs to the UBALD family.

29088:LOC110592270
gene id: 29088:LOC110592270
uniprot id: A0A8M1M8D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

29088:TRAF5
gene id: 29088:TRAF5
uniprot id: A0A2Y9GJP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

29088:LOC110580887
gene id: 29088:LOC110580887
uniprot id: A0A2Y9H8W1
names: Subcellular Location Annotation
messages: acrosome

29088:ARHGDIG
gene id: 29088:ARHGDIG
uniprot id: A0A2Y9HUT1
names: Similarity
messages: Belongs to the Rho GDI family.

29088:MICAL3
gene id: 29088:MICAL3
uniprot id: A0A2Y9H9I2
uniprot id: A0A8M1MFR3
uniprot id: A0A8M1MKN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

29088:LOC110578919
gene id: 29088:LOC110578919
uniprot id: A0A2Y9GY08
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

29088:RHPN1
gene id: 29088:RHPN1
uniprot id: A0A2Y9GYD7
names: Similarity
messages: Belongs to the RHPN family.

29088:PHOX2A
gene id: 29088:PHOX2A
uniprot id: A0A2Y9I9H8
names: Subcellular Location Annotation
messages: Nucleus

29088:COQ2
gene id: 29088:COQ2
uniprot id: A0A2Y9I2J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
messages: Mitochondrion inner membrane

29088:MYCBP2
gene id: 29088:MYCBP2
uniprot id: A0A8M1M8Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RING-Cys relay (RCR) family.
messages: axon

29088:TECRL
gene id: 29088:TECRL
uniprot id: A0A2Y9I2B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

29088:LOC110586870
gene id: 29088:LOC110586870
uniprot id: A0A2Y9HM82
uniprot id: A0A2Y9HSR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110586760
gene id: 29088:LOC110586760
uniprot id: A0A2Y9HLV6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:CHST8
gene id: 29088:CHST8
uniprot id: A0A2Y9HYP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:LOC110591928
gene id: 29088:LOC110591928
uniprot id: A0A8M1M889
names: Caution
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association.
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Cell membrane
messages: Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer (37LRP) and homodimer (67LR). Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with RPS21. Interacts with several laminins including at least LAMB1. Interacts with MDK. The mature dimeric form interacts with PPP1R16B (via its fourth ankyrin repeat). Interacts with PPP1CA only in the presence of PPP1R16B.
messages: Nucleus
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA.
messages: This protein appears to have acquired a second function as a laminin receptor specifically in the vertebrate lineage.

29088:GTF2H5
gene id: 29088:GTF2H5
uniprot id: A0A2Y9HI78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

29088:LOC110573402
gene id: 29088:LOC110573402
uniprot id: A0A8M1MED5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

29088:POLR3GL
gene id: 29088:POLR3GL
uniprot id: A0A2Y9GX22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

29088:BCL2L1
gene id: 29088:BCL2L1
uniprot id: A0A2Y9GZL9
uniprot id: A0A2Y9H659
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane
messages: Mitochondrion matrix
messages: Nucleus membrane
messages: centrosome
messages: cytosol
messages: synaptic vesicle membrane

29088:ERG28
gene id: 29088:ERG28
uniprot id: A0A2Y9G901
uniprot id: A0A2Y9G948
uniprot id: A0A2Y9GCJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:MDK
gene id: 29088:MDK
uniprot id: A0A2Y9GMH6
names: Similarity
messages: Belongs to the pleiotrophin family.

29088:NOL10
gene id: 29088:NOL10
uniprot id: A0A2Y9HUF6
uniprot id: A0A8M1MKQ0
uniprot id: A0A8M1MKQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat NOL10/ENP2 family.
messages: nucleolus

29088:TMEM216
gene id: 29088:TMEM216
uniprot id: A0A2Y9GPD7
names: Subcellular Location Annotation
messages: Membrane

29088:SERPINA7
gene id: 29088:SERPINA7
uniprot id: A0A2Y9G4F3
names: Similarity
messages: Belongs to the serpin family.

29088:SNX14
gene id: 29088:SNX14
uniprot id: A0A2Y9HC17
uniprot id: A0A2Y9HC91
uniprot id: A0A8M1MI23
uniprot id: A0A8M1MI25
uniprot id: A0A8M1MI27
uniprot id: A0A8M1MI30
uniprot id: A0A8M1MK45
uniprot id: A0A8M1MK49
uniprot id: A0A8M1MLF8
uniprot id: A0A8M1MLG2
uniprot id: A0A8M1MS10
names: Similarity
messages: Belongs to the sorting nexin family.

29088:CDC20
gene id: 29088:CDC20
uniprot id: A0A2Y9GJX0
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

29088:VTI1B
gene id: 29088:VTI1B
uniprot id: A0A2Y9G8U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

29088:FDFT1
gene id: 29088:FDFT1
uniprot id: A0A2Y9HSV4
uniprot id: A0A2Y9HXR5
uniprot id: A0A2Y9HZA4
uniprot id: A0A8M1M4U0
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

29088:AIFM1
gene id: 29088:AIFM1
uniprot id: A0A2Y9GQ33
uniprot id: A0A8M1M1X6
uniprot id: A0A8M1M5P2
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

29088:TMEM178B
gene id: 29088:TMEM178B
uniprot id: A0A2Y9HGY8
names: Similarity
messages: Belongs to the TMEM178 family.

29088:ADPRH
gene id: 29088:ADPRH
uniprot id: A0A2Y9H7N8
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

29088:SLC7A6
gene id: 29088:SLC7A6
uniprot id: A0A2Y9IBN9
names: Subcellular Location Annotation
messages: Membrane

29088:HNRNPA1
gene id: 29088:HNRNPA1
uniprot id: A0A2Y9GT09
uniprot id: A0A2Y9GT67
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:TCTN3
gene id: 29088:TCTN3
uniprot id: A0A8M1MF98
uniprot id: A0A8M1MIP5
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

29088:RGS9
gene id: 29088:RGS9
uniprot id: A0A2Y9G506
uniprot id: A0A2Y9G7I0
names: Subcellular Location Annotation
messages: Membrane

29088:ZNF830
gene id: 29088:ZNF830
uniprot id: A0A2Y9I813
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus speckle

29088:C10H20orf173
gene id: 29088:C10H20orf173
uniprot id: A0A2Y9H0D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

29088:FAM168A
gene id: 29088:FAM168A
uniprot id: A0A8M1MWS8
names: Similarity
messages: Belongs to the FAM168 family.

29088:KCNQ1
gene id: 29088:KCNQ1
uniprot id: A0A8M1MXJ6
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.1/KCNQ1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum
messages: Lateral cell membrane
messages: Membrane
messages: Membrane raft

29088:PRMT3
gene id: 29088:PRMT3
uniprot id: A0A2Y9GUJ5
names: Subcellular Location Annotation
messages: Cytoplasm

29088:ANO6
gene id: 29088:ANO6
uniprot id: A0A2Y9I920
uniprot id: A0A2Y9I957
uniprot id: A0A2Y9I9M9
uniprot id: A0A2Y9IDI9
uniprot id: A0A2Y9IGB9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:HEG1
gene id: 29088:HEG1
uniprot id: A0A8M1MYH6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:SERPINB5
gene id: 29088:SERPINB5
uniprot id: A0A2Y9GX13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family. Ov-serpin subfamily.
messages: extracellular space

29088:LOC110577191
gene id: 29088:LOC110577191
uniprot id: A0A2Y9GSC4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

29088:KCNJ1
gene id: 29088:KCNJ1
uniprot id: A0A2Y9HKL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

29088:ID4
gene id: 29088:ID4
uniprot id: A0A2Y9HS34
names: Subcellular Location Annotation
messages: Nucleus

29088:ACTL10
gene id: 29088:ACTL10
uniprot id: A0A2Y9H4U1
names: Similarity
messages: Belongs to the actin family.

29088:LOC110570685
gene id: 29088:LOC110570685
uniprot id: A0A8M1MK26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

29088:MYB
gene id: 29088:MYB
uniprot id: A0A2Y9HB47
uniprot id: A0A2Y9HBG6
uniprot id: A0A2Y9HH82
uniprot id: A0A2Y9HHV6
uniprot id: A0A8M1MHF2
uniprot id: A0A8M1MJI4
uniprot id: A0A8M1MRC2
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110589149
gene id: 29088:LOC110589149
uniprot id: A0A8M1MHE5
names: Similarity
messages: Belongs to the SKP1 family.

29088:PKP4
gene id: 29088:PKP4
uniprot id: A0A2Y9I5K6
uniprot id: A0A2Y9I9R4
uniprot id: A0A2Y9IC75
uniprot id: A0A8M1M740
names: Similarity
messages: Belongs to the beta-catenin family.

29088:HPS5
gene id: 29088:HPS5
uniprot id: A0A8M1MR60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPS5 family.
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6.
messages: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
messages: cytosol

29088:EIF2S2
gene id: 29088:EIF2S2
uniprot id: A0A2Y9GZL5
uniprot id: A0A8M1MMD3
uniprot id: A0A8M1MMD6
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

29088:EVX2
gene id: 29088:EVX2
uniprot id: A0A2Y9IC04
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110576725
gene id: 29088:LOC110576725
uniprot id: A0A2Y9GUR8
uniprot id: A0A8M1MGE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

29088:LOC110593364
gene id: 29088:LOC110593364
uniprot id: A0A2Y9IFY1
names: Similarity
messages: Belongs to the folate receptor family.

29088:FREM1
gene id: 29088:FREM1
uniprot id: A0A2Y9GG28
names: Similarity
messages: Belongs to the FRAS1 family.

29088:LOC110592784
gene id: 29088:LOC110592784
uniprot id: A0A2Y9I787
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tdpoz family.
messages: Nucleus speckle

29088:TSFM
gene id: 29088:TSFM
uniprot id: A0A2Y9H0J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Mitochondrion

29088:LOC110571297
gene id: 29088:LOC110571297
uniprot id: A0A8M1M877
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

29088:LOC110578902
gene id: 29088:LOC110578902
uniprot id: A0A8M1MAU6
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

29088:LOC110587510
gene id: 29088:LOC110587510
uniprot id: A0A2Y9HVL4
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

29088:LOC110576584
gene id: 29088:LOC110576584
uniprot id: A0A2Y9GW15
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:RAB3C
gene id: 29088:RAB3C
uniprot id: A0A2Y9I1C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

29088:DUOXA1
gene id: 29088:DUOXA1
uniprot id: A0A2Y9HNE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

29088:SEMA5B
gene id: 29088:SEMA5B
uniprot id: A0A8M1M8Y2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:MIOS
gene id: 29088:MIOS
uniprot id: A0A2Y9H0X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat mio family.
messages: Lysosome membrane

29088:ABCG5
gene id: 29088:ABCG5
uniprot id: A0A8M1MQH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

29088:LOC110593478
gene id: 29088:LOC110593478
uniprot id: A0A2Y9I8X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:PTGFR
gene id: 29088:PTGFR
uniprot id: A0A2Y9H2P4
uniprot id: A0A2Y9H2Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:ADCY9
gene id: 29088:ADCY9
uniprot id: A0A2Y9HVW5
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

29088:TRAPPC3
gene id: 29088:TRAPPC3
uniprot id: A0A2Y9GPV7
uniprot id: A0A8M1MA56
uniprot id: A0A8M1MG19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

29088:BCL2L13
gene id: 29088:BCL2L13
uniprot id: A0A2Y9H4D8
uniprot id: A0A8M1MAM0
names: Similarity
messages: Belongs to the Bcl-2 family.

29088:SYNGR2
gene id: 29088:SYNGR2
uniprot id: A0A2Y9GBS5
uniprot id: A0A2Y9GBX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

29088:WASL
gene id: 29088:WASL
uniprot id: A0A2Y9HTQ6
names: Subcellular Location Annotation
messages: Nucleus

29088:BEX5
gene id: 29088:BEX5
uniprot id: A0A2Y9HPJ7
names: Similarity
messages: Belongs to the BEX family.

29088:LOC110573658
gene id: 29088:LOC110573658
uniprot id: A0A2Y9GFS9
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

29088:PPP2CA
gene id: 29088:PPP2CA
uniprot id: A0A2Y9I8Q6
uniprot id: A0A8M1MJ11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

29088:FAS
gene id: 29088:FAS
uniprot id: A0A2Y9HJH1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

29088:LOC110578248
gene id: 29088:LOC110578248
uniprot id: A0A2Y9H072
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

29088:FZD3
gene id: 29088:FZD3
uniprot id: A0A2Y9HSI3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:KCNA7
gene id: 29088:KCNA7
uniprot id: A0A2Y9GFZ7
names: Subcellular Location Annotation
messages: Membrane

29088:GTF2E1
gene id: 29088:GTF2E1
uniprot id: A0A2Y9H949
names: Function
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

29088:MRPL58
gene id: 29088:MRPL58
uniprot id: A0A2Y9GEN1
uniprot id: A0A2Y9GGA2
names: Subcellular Location Annotation
messages: Mitochondrion

29088:EID1
gene id: 29088:EID1
uniprot id: A0A2Y9HDL6
names: Subcellular Location Annotation
messages: Nucleus

29088:SCAI
gene id: 29088:SCAI
uniprot id: A0A2Y9H688
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAI family.
messages: Cytoplasm
messages: Interacts with DIAPH1. Forms a nuclear ternary complex with MRTFA and SRF.
messages: Nucleus
messages: Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity.

29088:CCL26
gene id: 29088:CCL26
uniprot id: A0A2Y9I274
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

29088:MTERF1
gene id: 29088:MTERF1
uniprot id: A0A2Y9H644
names: Similarity
messages: Belongs to the mTERF family.

29088:UBE3D
gene id: 29088:UBE3D
uniprot id: A0A2Y9HAU9
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.

29088:LOC110594205
gene id: 29088:LOC110594205
uniprot id: A0A8M1M054
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

29088:TSPAN33
gene id: 29088:TSPAN33
uniprot id: A0A2Y9HU25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

29088:CUL7
gene id: 29088:CUL7
uniprot id: A0A2Y9HE49
uniprot id: A0A8M1MKK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cullin family.
messages: Cytoplasm

29088:ISCA1
gene id: 29088:ISCA1
uniprot id: A0A2Y9G3I9
uniprot id: A0A2Y9G635
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

29088:IMMP2L
gene id: 29088:IMMP2L
uniprot id: A0A8M1MPQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family. IMP2 subfamily.
messages: Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Membrane
messages: Mitochondrion inner membrane

29088:EHD1
gene id: 29088:EHD1
uniprot id: A0A2Y9GTM3
uniprot id: A0A8M1MS90
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

29088:ATP1B4
gene id: 29088:ATP1B4
uniprot id: A0A2Y9GR57
uniprot id: A0A2Y9GV80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

29088:MAP6D1
gene id: 29088:MAP6D1
uniprot id: A0A2Y9H9A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STOP family.
messages: cytoskeleton

29088:AIF1
gene id: 29088:AIF1
uniprot id: A0A2Y9HSE5
names: Subcellular Location Annotation
messages: ruffle membrane

29088:TRMT61A
gene id: 29088:TRMT61A
uniprot id: A0A2Y9G8W8
uniprot id: A0A8M1MMW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

29088:SYPL1
gene id: 29088:SYPL1
uniprot id: A0A2Y9GMI5
uniprot id: A0A8M1MPQ6
uniprot id: A0A8M1MPQ8
uniprot id: A0A8M1MRL8
uniprot id: A0A8M1MSZ5
uniprot id: A0A8M1MY21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

29088:DNAJC2
gene id: 29088:DNAJC2
uniprot id: A0A2Y9H0Y9
uniprot id: A0A8M1MPT2
uniprot id: A0A8M1MRP1
names: Function
names: Subcellular Location Annotation
messages: Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation.
messages: cytosol

29088:ECHDC1
gene id: 29088:ECHDC1
uniprot id: A0A2Y9HCA7
uniprot id: A0A2Y9HIT1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

29088:ADCY4
gene id: 29088:ADCY4
uniprot id: A0A2Y9HI76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

29088:LOC110589771
gene id: 29088:LOC110589771
uniprot id: A0A2Y9HWS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

29088:ALDH3A2
gene id: 29088:ALDH3A2
uniprot id: A0A2Y9HEY9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

29088:ACTL8
gene id: 29088:ACTL8
uniprot id: A0A2Y9GMP0
names: Similarity
messages: Belongs to the actin family.

29088:LOC110570674
gene id: 29088:LOC110570674
uniprot id: A0A2Y9G5U1
uniprot id: A0A8M1MUV1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

29088:NELL2
gene id: 29088:NELL2
uniprot id: A0A2Y9I9G8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ART5
gene id: 29088:ART5
uniprot id: A0A2Y9I9F0
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

29088:MSX1
gene id: 29088:MSX1
uniprot id: A0A2Y9G2G8
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110593575
gene id: 29088:LOC110593575
uniprot id: A0A2Y9I9X3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:C6H1orf43
gene id: 29088:C6H1orf43
uniprot id: A0A2Y9GEX6
uniprot id: A0A2Y9GF38
uniprot id: A0A2Y9GJR2
uniprot id: A0A8M1MGE7
uniprot id: A0A8M1MN00
names: Function
names: Subcellular Location Annotation
messages: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion

29088:IFNB1
gene id: 29088:IFNB1
uniprot id: A0A2Y9HMJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

29088:MTMR2
gene id: 29088:MTMR2
uniprot id: A0A2Y9G7A0
uniprot id: A0A2Y9GAH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

29088:WAS
gene id: 29088:WAS
uniprot id: A0A8M1M977
names: Subcellular Location Annotation
messages: Nucleus

29088:CPT1C
gene id: 29088:CPT1C
uniprot id: A0A2Y9GHJ6
uniprot id: A0A8M1MVX8
uniprot id: A0A8M1MXA9
uniprot id: A0A8M1MZE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

29088:TMEM150B
gene id: 29088:TMEM150B
uniprot id: A0A8M1MVR2
names: Subcellular Location Annotation
messages: Membrane

29088:LRP8
gene id: 29088:LRP8
uniprot id: A0A2Y9GKA9
uniprot id: A0A2Y9GNW6
uniprot id: A0A8M1M863
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ZNF326
gene id: 29088:ZNF326
uniprot id: A0A2Y9H237
uniprot id: A0A2Y9H254
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AKAP95 family.
messages: Nucleus matrix

29088:ATRAID
gene id: 29088:ATRAID
uniprot id: A0A2Y9HTK1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110588787
gene id: 29088:LOC110588787
uniprot id: A0A2Y9HSW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat fritz family.
messages: Cell membrane
messages: Membrane
messages: cilium axoneme

29088:LOC110584392
gene id: 29088:LOC110584392
uniprot id: A0A8M1MRS4
names: Similarity
messages: Belongs to the PA28 family.

29088:DUSP1
gene id: 29088:DUSP1
uniprot id: A0A2Y9HXF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

29088:PTGER4
gene id: 29088:PTGER4
uniprot id: A0A2Y9HKB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FEM1A.
messages: Membrane
messages: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

29088:PNPLA1
gene id: 29088:PNPLA1
uniprot id: A0A2Y9GM88
uniprot id: A0A2Y9GMD2
uniprot id: A0A2Y9GR82
uniprot id: A0A2Y9GSX9
uniprot id: A0A8M1MHQ5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:NDUFS7
gene id: 29088:NDUFS7
uniprot id: A0A2Y9IAE6
uniprot id: A0A2Y9IB07
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

29088:LOC110579906
gene id: 29088:LOC110579906
uniprot id: A0A2Y9H0U8
names: Similarity
messages: Belongs to the NDK family.

29088:LOC110574723
gene id: 29088:LOC110574723
uniprot id: A0A2Y9GJ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

29088:GIMAP4
gene id: 29088:GIMAP4
uniprot id: A0A8M1MY28
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

29088:EXOC6B
gene id: 29088:EXOC6B
uniprot id: A0A2Y9HTM7
uniprot id: A0A2Y9I016
uniprot id: A0A8M1MLV0
uniprot id: A0A8M1MQ48
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

29088:LOC110585538
gene id: 29088:LOC110585538
uniprot id: A0A8M1MNG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110574471
gene id: 29088:LOC110574471
uniprot id: A0A2Y9GIB5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ENSA
gene id: 29088:ENSA
uniprot id: A0A2Y9H1A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

29088:LOC110573938
gene id: 29088:LOC110573938
uniprot id: A0A8M1MI69
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

29088:LOC110589295
gene id: 29088:LOC110589295
uniprot id: A0A2Y9I040
uniprot id: A0A2Y9I1P1
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:GABRG3
gene id: 29088:GABRG3
uniprot id: A0A8M1MSM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:KHDRBS1
gene id: 29088:KHDRBS1
uniprot id: A0A2Y9GL07
uniprot id: A0A8M1M953
names: Similarity
messages: Belongs to the KHDRBS family.

29088:SCARF1
gene id: 29088:SCARF1
uniprot id: A0A2Y9I8C3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110590388
gene id: 29088:LOC110590388
uniprot id: A0A2Y9I5L6
names: Function
names: Similarity
messages: Belongs to the PET191 family.
messages: Involved in an early step of the mitochondrial complex IV assembly process.

29088:DLST
gene id: 29088:DLST
uniprot id: A0A2Y9G893
uniprot id: A0A2Y9G8D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

29088:GNA12
gene id: 29088:GNA12
uniprot id: A0A2Y9GDR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

29088:STC2
gene id: 29088:STC2
uniprot id: A0A2Y9HQU6
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

29088:CD79A
gene id: 29088:CD79A
uniprot id: A0A2Y9HE00
uniprot id: A0A8M1MZJ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:SLC25A23
gene id: 29088:SLC25A23
uniprot id: A0A8M1MML0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

29088:RNF13
gene id: 29088:RNF13
uniprot id: A0A2Y9GUU0
uniprot id: A0A8M1MQU8
uniprot id: A0A8M1MSQ4
names: Subcellular Location Annotation
messages: Membrane

29088:APPL1
gene id: 29088:APPL1
uniprot id: A0A2Y9HFX1
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: Nucleus
messages: phagosome
messages: ruffle

29088:DPYSL4
gene id: 29088:DPYSL4
uniprot id: A0A2Y9IAZ7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

29088:LAMA3
gene id: 29088:LAMA3
uniprot id: A0A2Y9GV46
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

29088:INTS7
gene id: 29088:INTS7
uniprot id: A0A8M1MEL3
uniprot id: A0A8M1MEQ0
uniprot id: A0A8M1MGR6
uniprot id: A0A8M1MI54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 7 family.
messages: Nucleus

29088:FAM221A
gene id: 29088:FAM221A
uniprot id: A0A2Y9H691
names: Similarity
messages: Belongs to the FAM221 family.

29088:LOC110573999
gene id: 29088:LOC110573999
uniprot id: A0A2Y9GLN5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).
messages: Nucleus

29088:HSPA9
gene id: 29088:HSPA9
uniprot id: A0A2Y9I791
names: Similarity
messages: Belongs to the heat shock protein 70 family.

29088:MRPL9
gene id: 29088:MRPL9
uniprot id: A0A2Y9GWV5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.

29088:NKX2-8
gene id: 29088:NKX2-8
uniprot id: A0A2Y9I6K6
names: Subcellular Location Annotation
messages: Nucleus

29088:SSR3
gene id: 29088:SSR3
uniprot id: A0A2Y9I2V9
uniprot id: A0A8M1MEN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

29088:TMEM65
gene id: 29088:TMEM65
uniprot id: A0A2Y9GXR4
names: Subcellular Location Annotation
messages: Membrane

29088:ITGAL
gene id: 29088:ITGAL
uniprot id: A0A2Y9HXM5
uniprot id: A0A2Y9I415
uniprot id: A0A8M1MB02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

29088:PRDM1
gene id: 29088:PRDM1
uniprot id: A0A2Y9HAN8
uniprot id: A0A2Y9HGR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.
messages: Nucleus
messages: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.

29088:NTNG1
gene id: 29088:NTNG1
uniprot id: A0A8M1MB63
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110577876
gene id: 29088:LOC110577876
uniprot id: A0A2Y9GYW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

29088:FGF17
gene id: 29088:FGF17
uniprot id: A0A2Y9HSA6
uniprot id: A0A2Y9HSS2
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

29088:GOLT1B
gene id: 29088:GOLT1B
uniprot id: A0A2Y9H3R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

29088:MADD
gene id: 29088:MADD
uniprot id: A0A2Y9GPG6
uniprot id: A0A2Y9GPK7
uniprot id: A0A8M1MR61
uniprot id: A0A8M1MSI6
uniprot id: A0A8M1MXV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MADD family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

29088:DCBLD1
gene id: 29088:DCBLD1
uniprot id: A0A8M1MI20
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:GIPR
gene id: 29088:GIPR
uniprot id: A0A2Y9GCN4
names: Subcellular Location Annotation
messages: Membrane

29088:S1PR3
gene id: 29088:S1PR3
uniprot id: A0A2Y9HE72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:ATP4B
gene id: 29088:ATP4B
uniprot id: A0A2Y9HQH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

29088:BIRC2
gene id: 29088:BIRC2
uniprot id: A0A2Y9HR82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IAP family.
messages: Cytoplasm
messages: Nucleus

29088:LOC110576280
gene id: 29088:LOC110576280
uniprot id: A0A8M1MRT3
names: Similarity
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

29088:DNMT3A
gene id: 29088:DNMT3A
uniprot id: A0A2Y9HNR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

29088:LOC110577431
gene id: 29088:LOC110577431
uniprot id: A0A2Y9GX75
names: Similarity
messages: Belongs to the intermediate filament family.

29088:LOC110580601
gene id: 29088:LOC110580601
uniprot id: A0A2Y9H2V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:GRAMD1B
gene id: 29088:GRAMD1B
uniprot id: A0A2Y9HR93
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:ZNF703
gene id: 29088:ZNF703
uniprot id: A0A2Y9GDU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

29088:STARD6
gene id: 29088:STARD6
uniprot id: A0A2Y9GW18
names: Function
messages: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.

29088:SLC35B4
gene id: 29088:SLC35B4
uniprot id: A0A2Y9HG23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

29088:PRPF3
gene id: 29088:PRPF3
uniprot id: A0A2Y9H115
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).

29088:SLC47A1
gene id: 29088:SLC47A1
uniprot id: A0A2Y9HL17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

29088:LOC110580975
gene id: 29088:LOC110580975
uniprot id: A0A8M1MEC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

29088:OVOL1
gene id: 29088:OVOL1
uniprot id: A0A2Y9GPL6
uniprot id: A0A2Y9GVF4
names: Subcellular Location Annotation
messages: Nucleus

29088:USP9X
gene id: 29088:USP9X
uniprot id: A0A2Y9GI97
uniprot id: A0A8M1M9D2
names: Similarity
messages: Belongs to the peptidase C19 family.

29088:NPPC
gene id: 29088:NPPC
uniprot id: A0A2Y9H324
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

29088:SMPD2
gene id: 29088:SMPD2
uniprot id: A0A2Y9HAZ6
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

29088:C9
gene id: 29088:C9
uniprot id: A0A2Y9HRK6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

29088:MFSD6L
gene id: 29088:MFSD6L
uniprot id: A0A2Y9HFM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

29088:VPS26A
gene id: 29088:VPS26A
uniprot id: A0A2Y9HUJ0
uniprot id: A0A2Y9HV31
uniprot id: A0A2Y9I1F9
names: Similarity
messages: Belongs to the VPS26 family.

29088:LOC110587381
gene id: 29088:LOC110587381
uniprot id: A0A2Y9HVC0
names: Similarity
messages: Belongs to the FAM228 family.

29088:RAMP1
gene id: 29088:RAMP1
uniprot id: A0A8M1MEG6
names: Similarity
messages: Belongs to the RAMP family.

29088:VANGL1
gene id: 29088:VANGL1
uniprot id: A0A2Y9H7E7
uniprot id: A0A8M1MD89
uniprot id: A0A8M1MHY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

29088:GSTZ1
gene id: 29088:GSTZ1
uniprot id: A0A2Y9GAY5
uniprot id: A0A2Y9GBX4
uniprot id: A0A8M1MT18
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

29088:SEMA6A
gene id: 29088:SEMA6A
uniprot id: A0A2Y9I7A3
uniprot id: A0A8M1MPD7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:CHRNE
gene id: 29088:CHRNE
uniprot id: A0A2Y9HFD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:DBNL
gene id: 29088:DBNL
uniprot id: A0A2Y9I5S0
uniprot id: A0A2Y9I6K4
uniprot id: A0A8M1MT26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABP1 family.
messages: Early endosome
messages: Golgi apparatus membrane
messages: Perikaryon
messages: Postsynaptic density
messages: cell cortex
messages: clathrin-coated vesicle membrane
messages: dendrite
messages: lamellipodium
messages: neuron projection
messages: podosome
messages: ruffle

29088:PPP1R15A
gene id: 29088:PPP1R15A
uniprot id: A0A2Y9GHF2
uniprot id: A0A8M1MY25
names: Similarity
messages: Belongs to the PPP1R15 family.

29088:CHIA
gene id: 29088:CHIA
uniprot id: A0A2Y9H2R6
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

29088:CLRN2
gene id: 29088:CLRN2
uniprot id: A0A2Y9GBB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

29088:LOC110593170
gene id: 29088:LOC110593170
uniprot id: A0A8M1MV66
names: Similarity
messages: Belongs to the CCDC90 family.

29088:SMG6
gene id: 29088:SMG6
uniprot id: A0A2Y9I8H3
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini.
messages: Plays a role in nonsense-mediated mRNA decay.
messages: The PINc domain confers endonuclease activity and is expected to bind the catalytic metal ion.
messages: cytosol
messages: nucleolus
messages: telomere

29088:SERPINE2
gene id: 29088:SERPINE2
uniprot id: A0A2Y9GHK4
names: Similarity
messages: Belongs to the serpin family.

29088:CORO6
gene id: 29088:CORO6
uniprot id: A0A2Y9I785
uniprot id: A0A2Y9I7I1
uniprot id: A0A2Y9I815
uniprot id: A0A8M1MX92
uniprot id: A0A8M1MZ49
names: Similarity
messages: Belongs to the WD repeat coronin family.

29088:WASHC1
gene id: 29088:WASHC1
uniprot id: A0A2Y9H4C6
uniprot id: A0A2Y9H4E4
uniprot id: A0A8M1MC96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WASH1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Recycling endosome membrane

29088:LOC110592033
gene id: 29088:LOC110592033
uniprot id: A0A8M1M9P8
names: Similarity
messages: Belongs to the DEAD box helicase family.

29088:COPS9
gene id: 29088:COPS9
uniprot id: A0A2Y9G926
names: Similarity
messages: Belongs to the CSN9 family.

29088:RPGRIP1
gene id: 29088:RPGRIP1
uniprot id: A0A2Y9HPH8
names: Similarity
messages: Belongs to the RPGRIP1 family.

29088:RPL24
gene id: 29088:RPL24
uniprot id: A0A2Y9HFG7
uniprot id: A0A8M1MQZ5
uniprot id: A0A8M1MSB5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

29088:TMEM38A
gene id: 29088:TMEM38A
uniprot id: A0A2Y9GI52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

29088:IDNK
gene id: 29088:IDNK
uniprot id: A0A2Y9G413
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

29088:NUDT11
gene id: 29088:NUDT11
uniprot id: A0A2Y9G884
names: Similarity
messages: Belongs to the Nudix hydrolase family. DIPP subfamily.

29088:LOC110585201
gene id: 29088:LOC110585201
uniprot id: A0A8M1MMH8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

29088:LOC110581378
gene id: 29088:LOC110581378
uniprot id: A0A2Y9H5E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SOSS-C family.
messages: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs).
messages: Component of the SOSS complex.
messages: Nucleus

29088:TPD52L2
gene id: 29088:TPD52L2
uniprot id: A0A2Y9G5T6
uniprot id: A0A2Y9G6Z5
uniprot id: A0A8M1ML82
uniprot id: A0A8M1ML84
uniprot id: A0A8M1ML87
uniprot id: A0A8M1ML89
uniprot id: A0A8M1MN90
uniprot id: A0A8M1MPJ5
uniprot id: A0A8M1MVE1
names: Similarity
messages: Belongs to the TPD52 family.

29088:SRRD
gene id: 29088:SRRD
uniprot id: A0A2Y9I637
names: Similarity
messages: Belongs to the SRR1 family.

29088:RTN4IP1
gene id: 29088:RTN4IP1
uniprot id: A0A2Y9HAY0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

29088:CSF1
gene id: 29088:CSF1
uniprot id: A0A2Y9H247
names: Function
names: Subunit
messages: Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.
messages: Homodimer or heterodimer; disulfide-linked. Interacts with CSF1R.

29088:LOC110576135
gene id: 29088:LOC110576135
uniprot id: A0A2Y9GNT0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LY6G5C
gene id: 29088:LY6G5C
uniprot id: A0A2Y9HMD7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Forms oligomers.
messages: May have a role in hematopoietic cell differentiation.
messages: Secreted

29088:ADAM28
gene id: 29088:ADAM28
uniprot id: A0A2Y9HS64
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110572877
gene id: 29088:LOC110572877
uniprot id: A0A2Y9GHI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOSIP family.
messages: Cytoplasm
messages: Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.
messages: Nucleus

29088:LOC123324292
gene id: 29088:LOC123324292
uniprot id: A0A8M1M5F5
uniprot id: A0A8M1MLQ8
names: Similarity
messages: Belongs to the PPDPF family.

29088:CTSO
gene id: 29088:CTSO
uniprot id: A0A2Y9HRY6
uniprot id: A0A2Y9HSE4
uniprot id: A0A2Y9HXB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

29088:PPFIA2
gene id: 29088:PPFIA2
uniprot id: A0A2Y9H1S9
uniprot id: A0A2Y9H1U9
uniprot id: A0A2Y9H1W7
uniprot id: A0A2Y9H8C7
uniprot id: A0A2Y9H8D2
uniprot id: A0A8M1MA71
uniprot id: A0A8M1MDP9
uniprot id: A0A8M1MIF4
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

29088:CD247
gene id: 29088:CD247
uniprot id: A0A8M1MEV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD3Z/FCER1G family.
messages: Cell membrane
messages: Membrane

29088:TSPAN3
gene id: 29088:TSPAN3
uniprot id: A0A2Y9HCT6
uniprot id: A0A8M1MTD5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:SCML2
gene id: 29088:SCML2
uniprot id: A0A2Y9GJM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

29088:PIAS3
gene id: 29088:PIAS3
uniprot id: A0A2Y9GWW1
names: Similarity
messages: Belongs to the PIAS family.

29088:EIF4ENIF1
gene id: 29088:EIF4ENIF1
uniprot id: A0A8M1MYW6
names: Subcellular Location Annotation
messages: Cytoplasm

29088:LRRC7
gene id: 29088:LRRC7
uniprot id: A0A8M1M7Z4
uniprot id: A0A8M1M883
names: Similarity
messages: Belongs to the LAP (LRR and PDZ) protein family.

29088:EIF2B1
gene id: 29088:EIF2B1
uniprot id: A0A2Y9HRR5
uniprot id: A0A8M1MT58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.
messages: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
messages: Complex of five different subunits; alpha, beta, gamma, delta and epsilon.

29088:TET3
gene id: 29088:TET3
uniprot id: A0A2Y9HT42
uniprot id: A0A2Y9HTL3
uniprot id: A0A2Y9I021
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Chromosome
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

29088:INSR
gene id: 29088:INSR
uniprot id: A0A2Y9IA86
uniprot id: A0A2Y9IGT8
uniprot id: A0A8M1MKP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

29088:PXMP2
gene id: 29088:PXMP2
uniprot id: A0A2Y9HF55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

29088:GALNT13
gene id: 29088:GALNT13
uniprot id: A0A2Y9I3X3
uniprot id: A0A2Y9I8I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

29088:TCF7L1
gene id: 29088:TCF7L1
uniprot id: A0A8M1MP18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

29088:LOC110580322
gene id: 29088:LOC110580322
uniprot id: A0A2Y9H251
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

29088:ATP10D
gene id: 29088:ATP10D
uniprot id: A0A2Y9I519
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

29088:KRT7
gene id: 29088:KRT7
uniprot id: A0A2Y9IGR3
names: Similarity
messages: Belongs to the intermediate filament family.

29088:LOC110593176
gene id: 29088:LOC110593176
uniprot id: A0A8M1MWU9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

29088:LOC110589682
gene id: 29088:LOC110589682
uniprot id: A0A8M1MHR6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

29088:HNRNPAB
gene id: 29088:HNRNPAB
uniprot id: A0A2Y9I674
uniprot id: A0A2Y9I890
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:LOC110571798
gene id: 29088:LOC110571798
uniprot id: A0A8M1MGA4
names: Similarity
messages: Belongs to the TCTP family.

29088:TMEM200C
gene id: 29088:TMEM200C
uniprot id: A0A2Y9GX67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

29088:LIPT2
gene id: 29088:LIPT2
uniprot id: A0A2Y9I906
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Mitochondrion

29088:GBA
gene id: 29088:GBA
uniprot id: A0A2Y9GIK7
uniprot id: A0A2Y9GK33
uniprot id: A0A8M1MDA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 30 family.
messages: Lysosome membrane

29088:ABI3
gene id: 29088:ABI3
uniprot id: A0A2Y9IC12
uniprot id: A0A2Y9IER1
names: Similarity
messages: Belongs to the ABI family.

29088:CNTN2
gene id: 29088:CNTN2
uniprot id: A0A2Y9GYC1
names: Similarity
messages: Belongs to the immunoglobulin superfamily. Contactin family.

29088:LOC110571740
gene id: 29088:LOC110571740
uniprot id: A0A8M1MMV5
names: Similarity
messages: Belongs to the TMA7 family.

29088:POLR2I
gene id: 29088:POLR2I
uniprot id: A0A2Y9HY10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

29088:FTL
gene id: 29088:FTL
uniprot id: A0A2Y9GFZ1
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

29088:CCNA2
gene id: 29088:CCNA2
uniprot id: A0A2Y9GDP7
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

29088:SSBP4
gene id: 29088:SSBP4
uniprot id: A0A2Y9GID7
uniprot id: A0A2Y9GIF6
uniprot id: A0A2Y9GIM8
uniprot id: A0A2Y9GNN5
uniprot id: A0A8M1MVH4
uniprot id: A0A8M1MVI5
uniprot id: A0A8M1MVJ0
uniprot id: A0A8M1MX16
uniprot id: A0A8M1MX22
uniprot id: A0A8M1MX31
uniprot id: A0A8M1MXT3
uniprot id: A0A8M1MZB5
uniprot id: A0A8M1MZB9
names: Subcellular Location Annotation
messages: Nucleus

29088:IFNE
gene id: 29088:IFNE
uniprot id: A0A2Y9HAF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

29088:MCL1
gene id: 29088:MCL1
uniprot id: A0A2Y9GWV8
uniprot id: A0A8M1M9K6
uniprot id: A0A8M1MI10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: Membrane
messages: nucleoplasm

29088:ZSCAN29
gene id: 29088:ZSCAN29
uniprot id: A0A2Y9HGW0
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

29088:CLRN3
gene id: 29088:CLRN3
uniprot id: A0A2Y9IDR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

29088:ACLY
gene id: 29088:ACLY
uniprot id: A0A2Y9GEH7
uniprot id: A0A2Y9GEM0
uniprot id: A0A2Y9GJ20
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
messages: In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.

29088:MRPL47
gene id: 29088:MRPL47
uniprot id: A0A2Y9H948
uniprot id: A0A2Y9H996
uniprot id: A0A8M1M9Z3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

29088:FMN1
gene id: 29088:FMN1
uniprot id: A0A2Y9HGY4
uniprot id: A0A2Y9HHA2
names: Similarity
messages: Belongs to the formin homology family. Cappuccino subfamily.

29088:TRAF2
gene id: 29088:TRAF2
uniprot id: A0A2Y9H4V4
uniprot id: A0A8M1MRE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

29088:MARCHF9
gene id: 29088:MARCHF9
uniprot id: A0A2Y9H0J3
names: Subcellular Location Annotation
messages: Membrane

29088:ARHGEF11
gene id: 29088:ARHGEF11
uniprot id: A0A2Y9GF90
uniprot id: A0A2Y9GF98
uniprot id: A0A2Y9GJW9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

29088:PUF60
gene id: 29088:PUF60
uniprot id: A0A2Y9GYS8
uniprot id: A0A2Y9GYT3
uniprot id: A0A2Y9GZ48
uniprot id: A0A2Y9GZ52
uniprot id: A0A2Y9H3F3
uniprot id: A0A2Y9H3F8
uniprot id: A0A2Y9H5F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM half pint family.
messages: Nucleus

29088:JAG2
gene id: 29088:JAG2
uniprot id: A0A8M1MMS6
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

29088:PES1
gene id: 29088:PES1
uniprot id: A0A2Y9ICJ3
uniprot id: A0A8M1MW23
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pescadillo family.
messages: Chromosome
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome. Interacts with IRS1 and UBTF. May interact with MAP1B.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: Sumoylated.
messages: nucleolus
messages: nucleoplasm

29088:ATP6V0C
gene id: 29088:ATP6V0C
uniprot id: A0A2Y9HQH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane
messages: clathrin-coated vesicle membrane
messages: synaptic vesicle membrane

29088:SPTLC3
gene id: 29088:SPTLC3
uniprot id: A0A2Y9HXQ9
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

29088:DNAH17
gene id: 29088:DNAH17
uniprot id: A0A2Y9GGK2
names: Similarity
messages: Belongs to the dynein heavy chain family.

29088:UNC5CL
gene id: 29088:UNC5CL
uniprot id: A0A2Y9H7W4
names: Similarity
messages: Belongs to the unc-5 family.

29088:OPRM1
gene id: 29088:OPRM1
uniprot id: A0A2Y9HIW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: axon
messages: dendrite

29088:LOC110570393
gene id: 29088:LOC110570393
uniprot id: A0A2Y9G8J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
messages: Secreted

29088:UBE2A
gene id: 29088:UBE2A
uniprot id: A0A2Y9GRI0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

29088:MPC2
gene id: 29088:MPC2
uniprot id: A0A8M1MER4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

29088:CPSF3
gene id: 29088:CPSF3
uniprot id: A0A2Y9HP00
uniprot id: A0A2Y9HPE3
uniprot id: A0A2Y9HVS9
uniprot id: A0A8M1MP56
names: Subcellular Location Annotation
messages: Nucleus

29088:NPC1
gene id: 29088:NPC1
uniprot id: A0A2Y9GR83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

29088:IL13RA1
gene id: 29088:IL13RA1
uniprot id: A0A8M1M3A5
names: Subcellular Location Annotation
messages: Membrane

29088:RPS6KA2
gene id: 29088:RPS6KA2
uniprot id: A0A8M1MH63
uniprot id: A0A8M1MH67
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

29088:RIPK3
gene id: 29088:RIPK3
uniprot id: A0A2Y9HNN9
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:LOC110582333
gene id: 29088:LOC110582333
uniprot id: A0A2Y9H8J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:MEX3D
gene id: 29088:MEX3D
uniprot id: A0A8M1M7W0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:HTATSF1
gene id: 29088:HTATSF1
uniprot id: A0A2Y9GME7
names: Similarity
messages: Belongs to the HTATSF1 family.

29088:LOC110584674
gene id: 29088:LOC110584674
uniprot id: A0A8M1MUS4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

29088:UTP15
gene id: 29088:UTP15
uniprot id: A0A8M1MFL4
names: Subcellular Location Annotation
messages: nucleolus

29088:POLR2A
gene id: 29088:POLR2A
uniprot id: A0A2Y9HEK3
uniprot id: A0A8M1MVQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

29088:ZGPAT
gene id: 29088:ZGPAT
uniprot id: A0A2Y9G3J0
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CHD4/Mi-2; the interaction is direct.
messages: Nucleus

29088:FXYD6
gene id: 29088:FXYD6
uniprot id: A0A2Y9HJF5
uniprot id: A0A8M1MY15
names: Similarity
messages: Belongs to the FXYD family.

29088:EML3
gene id: 29088:EML3
uniprot id: A0A2Y9GPM6
uniprot id: A0A2Y9GTH6
names: Similarity
messages: Belongs to the WD repeat EMAP family.

29088:HSPE1
gene id: 29088:HSPE1
uniprot id: A0A2Y9HKK2
names: Similarity
messages: Belongs to the GroES chaperonin family.

29088:ERCC1
gene id: 29088:ERCC1
uniprot id: A0A8M1MVU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERCC1/RAD10/SWI10 family.
messages: Nucleus

29088:TMTC4
gene id: 29088:TMTC4
uniprot id: A0A8M1M8V8
uniprot id: A0A8M1MEM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

29088:MTERF3
gene id: 29088:MTERF3
uniprot id: A0A2Y9GXI7
uniprot id: A0A8M1MCC2
names: Similarity
messages: Belongs to the mTERF family.

29088:ZRANB1
gene id: 29088:ZRANB1
uniprot id: A0A2Y9I641
uniprot id: A0A8M1MHM8
names: Similarity
messages: Belongs to the peptidase C64 family.

29088:CRYBA2
gene id: 29088:CRYBA2
uniprot id: A0A2Y9IBU9
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

29088:RPL10L
gene id: 29088:RPL10L
uniprot id: A0A2Y9HZK4
uniprot id: A0A2Y9I5Z1
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

29088:ACOT6
gene id: 29088:ACOT6
uniprot id: A0A2Y9G8G6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

29088:CDV3
gene id: 29088:CDV3
uniprot id: A0A8M1M3Q7
names: Similarity
messages: Belongs to the CDV3 family.

29088:IDH3A
gene id: 29088:IDH3A
uniprot id: A0A2Y9GBC9
uniprot id: A0A2Y9GBD5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

29088:EXOSC9
gene id: 29088:EXOSC9
uniprot id: A0A2Y9GDS2
names: Subcellular Location Annotation
messages: Cytoplasm

29088:MYF6
gene id: 29088:MYF6
uniprot id: A0A2Y9H6Q9
names: Subcellular Location Annotation
messages: Nucleus

29088:GDPD1
gene id: 29088:GDPD1
uniprot id: A0A2Y9IEV1
uniprot id: A0A8M1MWH4
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

29088:LEPROT
gene id: 29088:LEPROT
uniprot id: A0A2Y9GC44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

29088:LOC110575800
gene id: 29088:LOC110575800
uniprot id: A0A2Y9GMM3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SERPINA3
gene id: 29088:SERPINA3
uniprot id: A0A8M1MMZ7
names: Similarity
messages: Belongs to the serpin family.

29088:LOC110592111
gene id: 29088:LOC110592111
uniprot id: A0A8M1MEZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: cytoskeleton

29088:ALMS1
gene id: 29088:ALMS1
uniprot id: A0A8M1MQ40
names: Subcellular Location Annotation
messages: centrosome

29088:UBE3A
gene id: 29088:UBE3A
uniprot id: A0A2Y9GBE4
uniprot id: A0A2Y9GBG8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
messages: Nucleus

29088:MMAB
gene id: 29088:MMAB
uniprot id: A0A2Y9I662
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

29088:GSTM3
gene id: 29088:GSTM3
uniprot id: A0A2Y9H2D6
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

29088:MAP4K3
gene id: 29088:MAP4K3
uniprot id: A0A2Y9HPD1
uniprot id: A0A2Y9HU95
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

29088:IL24
gene id: 29088:IL24
uniprot id: A0A2Y9GKL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

29088:LOC110589452
gene id: 29088:LOC110589452
uniprot id: A0A8M1MIT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B4 family.
messages: Nucleus

29088:DOK2
gene id: 29088:DOK2
uniprot id: A0A2Y9HS73
uniprot id: A0A2Y9HZ39
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

29088:NEIL1
gene id: 29088:NEIL1
uniprot id: A0A8M1MJD6
names: Similarity
messages: Belongs to the FPG family.

29088:LOC110582374
gene id: 29088:LOC110582374
uniprot id: A0A2Y9HFF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:NME7
gene id: 29088:NME7
uniprot id: A0A8M1MGA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: cilium axoneme

29088:IL1RN
gene id: 29088:IL1RN
uniprot id: A0A2Y9HP05
uniprot id: A0A2Y9HUB5
uniprot id: A0A2Y9HVT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
messages: Belongs to the IL-1 family.
messages: Secreted

29088:CHRM4
gene id: 29088:CHRM4
uniprot id: A0A2Y9GT89
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

29088:LOC110592357
gene id: 29088:LOC110592357
uniprot id: A0A8M1M9B8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

29088:TMEM151A
gene id: 29088:TMEM151A
uniprot id: A0A2Y9GP48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

29088:STK3
gene id: 29088:STK3
uniprot id: A0A2Y9GYF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Nucleus

29088:SYT16
gene id: 29088:SYT16
uniprot id: A0A2Y9I6I2
names: Similarity
messages: Belongs to the synaptotagmin family.

29088:LOC110588536
gene id: 29088:LOC110588536
uniprot id: A0A8M1M445
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

29088:BYSL
gene id: 29088:BYSL
uniprot id: A0A2Y9H7M2
uniprot id: A0A2Y9HD83
names: Similarity
messages: Belongs to the bystin family.

29088:PLBD1
gene id: 29088:PLBD1
uniprot id: A0A2Y9H3S4
uniprot id: A0A2Y9H3T1
uniprot id: A0A2Y9HAG0
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

29088:SAMD4B
gene id: 29088:SAMD4B
uniprot id: A0A8M1M0D4
uniprot id: A0A8M1M2Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

29088:XKR6
gene id: 29088:XKR6
uniprot id: A0A2Y9HYI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

29088:EYA2
gene id: 29088:EYA2
uniprot id: A0A2Y9GZI2
uniprot id: A0A8M1MLA1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

29088:EIF3K
gene id: 29088:EIF3K
uniprot id: A0A2Y9HYM4
uniprot id: A0A2Y9I3J9
uniprot id: A0A8M1M0Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit K family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with CCND3, but not with CCND1 and CCND2.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm
messages: Nucleus

29088:RBL1
gene id: 29088:RBL1
uniprot id: A0A2Y9GZE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

29088:VAMP2
gene id: 29088:VAMP2
uniprot id: A0A8M1MV45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

29088:DGKI
gene id: 29088:DGKI
uniprot id: A0A2Y9H9V6
uniprot id: A0A8M1MT16
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

29088:RUVBL1
gene id: 29088:RUVBL1
uniprot id: A0A2Y9HG92
uniprot id: A0A8M1MMX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

29088:KDM5A
gene id: 29088:KDM5A
uniprot id: A0A2Y9HB07
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

29088:INTS2
gene id: 29088:INTS2
uniprot id: A0A2Y9I937
uniprot id: A0A8M1MVI0
names: Similarity
messages: Belongs to the Integrator subunit 2 family.

29088:LRP12
gene id: 29088:LRP12
uniprot id: A0A2Y9GXQ1
uniprot id: A0A8M1MCD8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:GIPC1
gene id: 29088:GIPC1
uniprot id: A0A2Y9IAG6
uniprot id: A0A2Y9IHN6
names: Similarity
messages: Belongs to the GIPC family.

29088:ZNF394
gene id: 29088:ZNF394
uniprot id: A0A2Y9GA46
uniprot id: A0A2Y9GDY9
names: Subcellular Location Annotation
messages: Nucleus

29088:FOLR2
gene id: 29088:FOLR2
uniprot id: A0A2Y9IG00
names: Similarity
messages: Belongs to the folate receptor family.

29088:ATP6V0E2
gene id: 29088:ATP6V0E2
uniprot id: A0A2Y9HA15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

29088:LOC110569699
gene id: 29088:LOC110569699
uniprot id: A0A2Y9G2N4
names: Similarity
messages: Belongs to the MORF4 family-associated protein family.

29088:HDX
gene id: 29088:HDX
uniprot id: A0A2Y9HAV0
names: Subcellular Location Annotation
messages: Nucleus

29088:LDB1
gene id: 29088:LDB1
uniprot id: A0A2Y9HUM9
uniprot id: A0A2Y9HUN3
uniprot id: A0A2Y9I0Z4
names: Similarity
messages: Belongs to the LDB family.

29088:IZUMO3
gene id: 29088:IZUMO3
uniprot id: A0A2Y9GCJ2
uniprot id: A0A8M1MRY6
names: Similarity
messages: Belongs to the Izumo family.

29088:MRPL17
gene id: 29088:MRPL17
uniprot id: A0A2Y9GQD0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

29088:BICC1
gene id: 29088:BICC1
uniprot id: A0A8M1MF11
names: Similarity
messages: Belongs to the BicC family.

29088:FAR1
gene id: 29088:FAR1
uniprot id: A0A2Y9GP58
uniprot id: A0A2Y9GT16
uniprot id: A0A2Y9GUR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

29088:TBX1
gene id: 29088:TBX1
uniprot id: A0A8M1MYT9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

29088:RPL23
gene id: 29088:RPL23
uniprot id: A0A2Y9I882
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Component of the large ribosomal subunit.

29088:ACADVL
gene id: 29088:ACADVL
uniprot id: A0A2Y9HEH8
uniprot id: A0A2Y9HEX0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

29088:LOC110586536
gene id: 29088:LOC110586536
uniprot id: A0A8M1MAP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

29088:LGR4
gene id: 29088:LGR4
uniprot id: A0A2Y9GP74
uniprot id: A0A8M1MR79
names: Subcellular Location Annotation
messages: Membrane

29088:RBM5
gene id: 29088:RBM5
uniprot id: A0A2Y9GTE2
uniprot id: A0A2Y9GTF3
uniprot id: A0A2Y9GXM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBM5/RBM10 family.
messages: Nucleus

29088:LOC110593302
gene id: 29088:LOC110593302
uniprot id: A0A2Y9I8C5
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

29088:ST8SIA4
gene id: 29088:ST8SIA4
uniprot id: A0A2Y9HTB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

29088:PHTF2
gene id: 29088:PHTF2
uniprot id: A0A8M1MYC7
names: Subcellular Location Annotation
messages: Membrane

29088:PLPPR2
gene id: 29088:PLPPR2
uniprot id: A0A2Y9IA17
uniprot id: A0A2Y9IEJ0
uniprot id: A0A2Y9IHA2
uniprot id: A0A8M1MG97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

29088:NUMB
gene id: 29088:NUMB
uniprot id: A0A2Y9G8V6
uniprot id: A0A2Y9G935
names: Function
messages: Plays a role in the process of neurogenesis.

29088:FOXI3
gene id: 29088:FOXI3
uniprot id: A0A2Y9HU46
names: Subcellular Location Annotation
messages: Nucleus

29088:ATP23
gene id: 29088:ATP23
uniprot id: A0A2Y9GUL3
uniprot id: A0A2Y9GUS0
names: Similarity
messages: Belongs to the peptidase M76 family.

29088:NAPRT
gene id: 29088:NAPRT
uniprot id: A0A2Y9GY78
uniprot id: A0A2Y9GY94
uniprot id: A0A2Y9H2I3
uniprot id: A0A8M1M8Y6
uniprot id: A0A8M1MCH2
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

29088:ACP5
gene id: 29088:ACP5
uniprot id: A0A2Y9IAK1
names: Cofactor
messages: Binds 2 iron ions per subunit.

29088:RPS26
gene id: 29088:RPS26
uniprot id: A0A2Y9H0C6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

29088:LCAT
gene id: 29088:LCAT
uniprot id: A0A2Y9ICI9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

29088:PARP12
gene id: 29088:PARP12
uniprot id: A0A2Y9HA30
names: Similarity
messages: Belongs to the ARTD/PARP family.

29088:TUBB
gene id: 29088:TUBB
uniprot id: A0A2Y9HLQ0
uniprot id: A0A2Y9HLX5
uniprot id: A0A8M1MHN9
uniprot id: A0A8M1MJS1
uniprot id: A0A8M1MRK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

29088:ACADS
gene id: 29088:ACADS
uniprot id: A0A2Y9I5F2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

29088:SAXO1
gene id: 29088:SAXO1
uniprot id: A0A2Y9GG67
names: Similarity
messages: Belongs to the FAM154 family.

29088:LOC110570570
gene id: 29088:LOC110570570
uniprot id: A0A8M1MCC6
names: Similarity
messages: Belongs to the NAC-beta family.

29088:LOC110575902
gene id: 29088:LOC110575902
uniprot id: A0A2Y9GS03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCC3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex. Thereby, plays an important role in ATP production by mitochondria. Cardiolipin-binding protein, it may also control the cardiolipin composition of mitochondria membranes and their morphology.

29088:CTSW
gene id: 29088:CTSW
uniprot id: A0A8M1MRY4
names: Similarity
messages: Belongs to the peptidase C1 family.

29088:LOC110570458
gene id: 29088:LOC110570458
uniprot id: A0A2Y9G8T3
names: Subcellular Location Annotation
messages: Membrane

29088:CCNG1
gene id: 29088:CCNG1
uniprot id: A0A2Y9HUZ5
names: Similarity
messages: Belongs to the cyclin family.

29088:ADRA2A
gene id: 29088:ADRA2A
uniprot id: A0A2Y9I1W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:CASR
gene id: 29088:CASR
uniprot id: A0A2Y9H8W6
uniprot id: A0A2Y9HEQ0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:LOC110574958
gene id: 29088:LOC110574958
uniprot id: A0A2Y9GK51
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110576922
gene id: 29088:LOC110576922
uniprot id: A0A8M1MTI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

29088:ABCB4
gene id: 29088:ABCB4
uniprot id: A0A2Y9H1S3
uniprot id: A0A2Y9H1U0
uniprot id: A0A2Y9H8A1
names: Subcellular Location Annotation
messages: Membrane

29088:UBE2N
gene id: 29088:UBE2N
uniprot id: A0A2Y9GZE9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

29088:LOC110570174
gene id: 29088:LOC110570174
uniprot id: A0A8M1MB58
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS21 family.

29088:PRKCA
gene id: 29088:PRKCA
uniprot id: A0A2Y9G7H4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domain.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus

29088:TTC39B
gene id: 29088:TTC39B
uniprot id: A0A8M1MSR3
names: Similarity
messages: Belongs to the TTC39 family.

29088:SIVA1
gene id: 29088:SIVA1
uniprot id: A0A2Y9G8P6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.
messages: Nucleus

29088:EXOC3L1
gene id: 29088:EXOC3L1
uniprot id: A0A2Y9IB50
names: Similarity
messages: Belongs to the SEC6 family.

29088:FAM131B
gene id: 29088:FAM131B
uniprot id: A0A2Y9HGA3
uniprot id: A0A8M1MQF3
names: Similarity
messages: Belongs to the FAM131 family.

29088:TMEM88B
gene id: 29088:TMEM88B
uniprot id: A0A8M1MFK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM88 family.
messages: Membrane

29088:EFHC1
gene id: 29088:EFHC1
uniprot id: A0A2Y9H7T7
names: Subcellular Location Annotation
messages: cilium axoneme

29088:HRH2
gene id: 29088:HRH2
uniprot id: A0A2Y9HRH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:LOC110577681
gene id: 29088:LOC110577681
uniprot id: A0A2Y9GU58
names: Similarity
messages: Belongs to the TPPP family.

29088:TSEN2
gene id: 29088:TSEN2
uniprot id: A0A2Y9HG19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

29088:PVALEF
gene id: 29088:PVALEF
uniprot id: A0A8M1MWW4
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

29088:LDLRAD4
gene id: 29088:LDLRAD4
uniprot id: A0A2Y9GHV5
uniprot id: A0A2Y9GI00
uniprot id: A0A8M1MUE0
uniprot id: A0A8M1MYR2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:CSK
gene id: 29088:CSK
uniprot id: A0A2Y9HIQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

29088:ETV2
gene id: 29088:ETV2
uniprot id: A0A2Y9HXY6
uniprot id: A0A8M1MWH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

29088:TAF9B
gene id: 29088:TAF9B
uniprot id: A0A2Y9GXX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

29088:PLD2
gene id: 29088:PLD2
uniprot id: A0A2Y9HLH0
uniprot id: A0A8M1MX08
names: Similarity
messages: Belongs to the phospholipase D family.

29088:RBPMS2
gene id: 29088:RBPMS2
uniprot id: A0A2Y9HD18
names: Subcellular Location Annotation
messages: Cytoplasm

29088:CCNL2
gene id: 29088:CCNL2
uniprot id: A0A2Y9GKI5
uniprot id: A0A2Y9GKP2
uniprot id: A0A2Y9GP45
names: Similarity
messages: Belongs to the cyclin family.

29088:PAN2
gene id: 29088:PAN2
uniprot id: A0A2Y9H077
uniprot id: A0A8M1MBU6
uniprot id: A0A8M1ME28
uniprot id: A0A8M1MKC9
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. Also acts as an important regulator of the HIF1A-mediated hypoxic response. Required for HIF1A mRNA stability independent of poly(A) tail length regulation.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts with ZFP36.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: P-body
messages: Positively regulated by the regulatory subunit PAN3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.

29088:DIMT1
gene id: 29088:DIMT1
uniprot id: A0A2Y9I192
uniprot id: A0A2Y9I1N9
uniprot id: A0A2Y9I859
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

29088:LOC110580326
gene id: 29088:LOC110580326
uniprot id: A0A2Y9H8R8
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

29088:FLOT2
gene id: 29088:FLOT2
uniprot id: A0A2Y9I6G9
uniprot id: A0A2Y9I7B0
uniprot id: A0A2Y9IDX4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Cell membrane
messages: Endosome
messages: Heterooligomeric complex of flotillin-1 and flotillin-2 and caveolin-1 and caveolin-2. Interacts with ECPAS.
messages: Heterooligomeric complex.
messages: Membrane
messages: caveola

29088:LOC110591501
gene id: 29088:LOC110591501
uniprot id: A0A8M1M6H4
names: Similarity
messages: Belongs to the ENTR1 family.

29088:RAB14
gene id: 29088:RAB14
uniprot id: A0A2Y9HB18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Recycling endosome
messages: phagosome
messages: trans-Golgi network membrane

29088:OLR1
gene id: 29088:OLR1
uniprot id: A0A2Y9H3Y5
names: Subcellular Location Annotation
messages: Membrane

29088:PARP1
gene id: 29088:PARP1
uniprot id: A0A2Y9GAQ1
uniprot id: A0A2Y9GBN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARTD/PARP family.
messages: Chromosome
messages: Interacts (when auto-poly-ADP-ribosylated) with AIFM1.
messages: Nucleus
messages: Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair.
messages: This cleavage form irreversibly binds to DNA breaks and interferes with DNA repair, promoting DNA damage-induced apoptosis.

29088:HRK
gene id: 29088:HRK
uniprot id: A0A2Y9HRX6
names: Function
names: Subcellular Location Annotation
messages: Mitochondrion
messages: Promotes apoptosis.

29088:PADI2
gene id: 29088:PADI2
uniprot id: A0A2Y9GLG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

29088:TRIM3
gene id: 29088:TRIM3
uniprot id: A0A2Y9GVV0
uniprot id: A0A8M1MPG2
uniprot id: A0A8M1MPH3
uniprot id: A0A8M1MRC8
names: Similarity
messages: Belongs to the TRIM/RBCC family.

29088:YARS1
gene id: 29088:YARS1
uniprot id: A0A2Y9GJJ2
uniprot id: A0A2Y9GN42
uniprot id: A0A2Y9GPR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Nucleus

29088:MEIS3
gene id: 29088:MEIS3
uniprot id: A0A2Y9GHA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

29088:LOC110588696
gene id: 29088:LOC110588696
uniprot id: A0A8M1MPF4
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

29088:DNAAF1
gene id: 29088:DNAAF1
uniprot id: A0A2Y9I336
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAAF1 family.
messages: Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli.
messages: cilium

29088:FOLH1B
gene id: 29088:FOLH1B
uniprot id: A0A8M1MSL2
uniprot id: A0A8M1MXW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

29088:SHROOM4
gene id: 29088:SHROOM4
uniprot id: A0A2Y9G5U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

29088:UBAP2L
gene id: 29088:UBAP2L
uniprot id: A0A2Y9GFD5
uniprot id: A0A2Y9GFE0
uniprot id: A0A2Y9GFI0
uniprot id: A0A2Y9GFJ6
uniprot id: A0A2Y9GFK1
uniprot id: A0A2Y9GFK4
uniprot id: A0A2Y9GIQ6
uniprot id: A0A2Y9GK76
uniprot id: A0A8M1MD98
uniprot id: A0A8M1MFC0
uniprot id: A0A8M1MGR3
names: Subcellular Location Annotation
messages: Cytoplasm

29088:EPHB2
gene id: 29088:EPHB2
uniprot id: A0A2Y9GMS1
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110574521
gene id: 29088:LOC110574521
uniprot id: A0A2Y9GLP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:CD8B
gene id: 29088:CD8B
uniprot id: A0A2Y9HNH9
names: Subcellular Location Annotation
messages: Membrane

29088:TAAR1
gene id: 29088:TAAR1
uniprot id: A0A2Y9HH60
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:FOXR2
gene id: 29088:FOXR2
uniprot id: A0A2Y9HYK3
names: Subcellular Location Annotation
messages: Nucleus

29088:PPP1R2C
gene id: 29088:PPP1R2C
uniprot id: A0A2Y9GER3
uniprot id: A0A2Y9GJ78
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 2 family.

29088:ABLIM1
gene id: 29088:ABLIM1
uniprot id: A0A2Y9HVS2
uniprot id: A0A2Y9HW97
uniprot id: A0A8M1MHL5
names: Subcellular Location Annotation
messages: Cytoplasm

29088:DEFB125
gene id: 29088:DEFB125
uniprot id: A0A2Y9H6L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

29088:B3GALNT1
gene id: 29088:B3GALNT1
uniprot id: A0A2Y9I9R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:VKORC1L1
gene id: 29088:VKORC1L1
uniprot id: A0A2Y9HWM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:FAT2
gene id: 29088:FAT2
uniprot id: A0A2Y9HYC2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:FKTN
gene id: 29088:FKTN
uniprot id: A0A2Y9H6A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LicD transferase family.
messages: Golgi apparatus membrane

29088:SETD6
gene id: 29088:SETD6
uniprot id: A0A2Y9IBT4
uniprot id: A0A2Y9IBZ6
uniprot id: A0A2Y9ICN0
uniprot id: A0A2Y9IJC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
messages: Nucleus
messages: Protein-lysine N-methyltransferase.

29088:UHRF2
gene id: 29088:UHRF2
uniprot id: A0A2Y9GG40
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Multi domain E3 ubiquitin ligase that also plays a role in DNA methylation and histone modifications.
messages: Nucleus
messages: The YDG domain mediates the interaction with histone H3.
messages: The tudor-like regions specifically recognize and bind histone H3 unmethylated at 'Arg-2' (H3R2me0), while the PHD-type zinc finger specifically recognizes and binds histone H3 trimethylated at 'Lys-9' (H3K9me3).

29088:PCK2
gene id: 29088:PCK2
uniprot id: A0A2Y9HH21
uniprot id: A0A8M1MIS1
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

29088:LIPE
gene id: 29088:LIPE
uniprot id: A0A2Y9HKV5
uniprot id: A0A2Y9HSD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'GDXG' lipolytic enzyme family.
messages: Cell membrane
messages: Lipid droplet
messages: caveola
messages: cytosol

29088:FABP6
gene id: 29088:FABP6
uniprot id: A0A2Y9HW42
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

29088:MCOLN1
gene id: 29088:MCOLN1
uniprot id: A0A2Y9I9N1
uniprot id: A0A2Y9I9N5
uniprot id: A0A2Y9I9Q9
uniprot id: A0A2Y9IAB7
uniprot id: A0A2Y9IE65
uniprot id: A0A2Y9IGW7
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

29088:IMPACT
gene id: 29088:IMPACT
uniprot id: A0A2Y9GRS2
uniprot id: A0A2Y9GVP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

29088:LOC110577414
gene id: 29088:LOC110577414
uniprot id: A0A2Y9GT24
names: Similarity
messages: Belongs to the PP3/GlyCAM-1 family.

29088:BDKRB2
gene id: 29088:BDKRB2
uniprot id: A0A2Y9GC61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.
messages: Membrane
messages: Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

29088:LOC110584339
gene id: 29088:LOC110584339
uniprot id: A0A2Y9HEH6
names: Similarity
messages: Belongs to the SPATA31 family.

29088:AP2A1
gene id: 29088:AP2A1
uniprot id: A0A2Y9GDF7
uniprot id: A0A8M1M383
uniprot id: A0A8M1M8F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif.
messages: coated pit

29088:LOC110585442
gene id: 29088:LOC110585442
uniprot id: A0A2Y9HI31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:MTMR4
gene id: 29088:MTMR4
uniprot id: A0A2Y9I917
uniprot id: A0A2Y9ICZ2
uniprot id: A0A8M1MVD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm
messages: Membrane

29088:CRAT
gene id: 29088:CRAT
uniprot id: A0A2Y9H647
uniprot id: A0A2Y9H650
uniprot id: A0A2Y9H689
uniprot id: A0A2Y9HBL3
uniprot id: A0A8M1MRU3
uniprot id: A0A8M1MV18
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

29088:CCNT2
gene id: 29088:CCNT2
uniprot id: A0A2Y9HIM8
uniprot id: A0A2Y9HIP2
names: Similarity
messages: Belongs to the cyclin family.

29088:IPO4
gene id: 29088:IPO4
uniprot id: A0A2Y9HPD3
names: Subcellular Location Annotation
messages: Cytoplasm

29088:ADAMTS8
gene id: 29088:ADAMTS8
uniprot id: A0A2Y9HK81
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:SLC35F1
gene id: 29088:SLC35F1
uniprot id: A0A2Y9HHR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

29088:SEMA5A
gene id: 29088:SEMA5A
uniprot id: A0A2Y9I7D3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:GPC5
gene id: 29088:GPC5
uniprot id: A0A2Y9HIS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

29088:GCAT
gene id: 29088:GCAT
uniprot id: A0A2Y9GZW6
uniprot id: A0A8M1MD05
uniprot id: A0A8M1MD57
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

29088:LOC110582225
gene id: 29088:LOC110582225
uniprot id: A0A2Y9H836
uniprot id: A0A2Y9HDS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tollip family.
messages: Cytoplasm

29088:IL13
gene id: 29088:IL13
uniprot id: A0A2Y9I1L4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-4/IL-13 family.
messages: Interacts with IL13RA2.
messages: Secreted

29088:SF3B4
gene id: 29088:SF3B4
uniprot id: A0A2Y9GX12
uniprot id: A0A8M1MC04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B4 family.
messages: Nucleus

29088:FBXO34
gene id: 29088:FBXO34
uniprot id: A0A2Y9I6D5
uniprot id: A0A8M1MLB3
names: Function
messages: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

29088:ABCC6
gene id: 29088:ABCC6
uniprot id: A0A2Y9HQE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

29088:MAGI1
gene id: 29088:MAGI1
uniprot id: A0A8M1MTK3
uniprot id: A0A8M1MVD9
uniprot id: A0A8M1MWP0
uniprot id: A0A8M1MWP3
uniprot id: A0A8M1MYY2
names: Subcellular Location Annotation
messages: Membrane

29088:PICALM
gene id: 29088:PICALM
uniprot id: A0A2Y9GS45
uniprot id: A0A2Y9GS50
uniprot id: A0A2Y9GS97
uniprot id: A0A2Y9GSD7
uniprot id: A0A2Y9GW97
uniprot id: A0A2Y9GWA2
uniprot id: A0A2Y9GXU5
uniprot id: A0A8M1MQT3
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

29088:HVCN1
gene id: 29088:HVCN1
uniprot id: A0A2Y9HRZ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hydrogen channel family.
messages: Homodimer.
messages: Membrane

29088:LOC110584884
gene id: 29088:LOC110584884
uniprot id: A0A8M1MN42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

29088:ADIPOR1
gene id: 29088:ADIPOR1
uniprot id: A0A8M1MEM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

29088:FNBP1L
gene id: 29088:FNBP1L
uniprot id: A0A2Y9H273
uniprot id: A0A2Y9H745
uniprot id: A0A8M1MHV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNBP1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Membrane
messages: Vesicle
messages: cell cortex
messages: cytoskeleton

29088:ACTN4
gene id: 29088:ACTN4
uniprot id: A0A2Y9I5E5
uniprot id: A0A8M1M0M6
uniprot id: A0A8M1M370
uniprot id: A0A8M1M8E5
names: Similarity
messages: Belongs to the alpha-actinin family.

29088:LOC110569925
gene id: 29088:LOC110569925
uniprot id: A0A2Y9G3G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

29088:LOC110585349
gene id: 29088:LOC110585349
uniprot id: A0A2Y9HP46
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110587153
gene id: 29088:LOC110587153
uniprot id: A0A8M1MG71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

29088:PVALB
gene id: 29088:PVALB
uniprot id: A0A2Y9GVG5
uniprot id: A0A2Y9GZT7
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

29088:FLI1
gene id: 29088:FLI1
uniprot id: A0A2Y9HJI8
uniprot id: A0A2Y9HJW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

29088:MLN
gene id: 29088:MLN
uniprot id: A0A2Y9GM06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the motilin family.
messages: Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.
messages: Secreted

29088:AMZ2
gene id: 29088:AMZ2
uniprot id: A0A2Y9G4Z4
uniprot id: A0A2Y9G4Z9
uniprot id: A0A2Y9G5H0
uniprot id: A0A2Y9G7J0
names: Function
names: Similarity
messages: Belongs to the peptidase M54 family.
messages: Probable zinc metalloprotease.

29088:SPACA4
gene id: 29088:SPACA4
uniprot id: A0A2Y9GD24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPACA4/bouncer family.
messages: Cell membrane
messages: Membrane

29088:NDUFB7
gene id: 29088:NDUFB7
uniprot id: A0A2Y9IHD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

29088:APOC2
gene id: 29088:APOC2
uniprot id: A0A2Y9GG70
uniprot id: A0A7F3QY95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C2 family.
messages: Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase.
messages: Secreted

29088:SRPX
gene id: 29088:SRPX
uniprot id: A0A2Y9GED2
uniprot id: A0A2Y9GH91
uniprot id: A0A2Y9GIQ7
uniprot id: A0A8M1M5B6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:SLC25A39
gene id: 29088:SLC25A39
uniprot id: A0A2Y9GDZ8
uniprot id: A0A2Y9GH29
uniprot id: A0A8M1MXT0
uniprot id: A0A8M1MZB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrial transporter required for glutathione import into mitochondria. Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles. Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis.
messages: Mitochondrion inner membrane

29088:LOC110590237
gene id: 29088:LOC110590237
uniprot id: A0A2Y9HYE4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

29088:SPOCK3
gene id: 29088:SPOCK3
uniprot id: A0A2Y9HRZ3
uniprot id: A0A2Y9HSE1
uniprot id: A0A2Y9HSF0
uniprot id: A0A2Y9HYW0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:EPHA4
gene id: 29088:EPHA4
uniprot id: A0A2Y9I5B4
uniprot id: A0A8M1M7E7
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome
messages: Membrane

29088:PHACTR3
gene id: 29088:PHACTR3
uniprot id: A0A2Y9G5S2
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

29088:CDH2
gene id: 29088:CDH2
uniprot id: A0A2Y9GRM9
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

29088:LOC110580765
gene id: 29088:LOC110580765
uniprot id: A0A2Y9H9Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Mitochondrion inner membrane

29088:SLC37A4
gene id: 29088:SLC37A4
uniprot id: A0A2Y9HJY4
uniprot id: A0A8M1MN61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

29088:PGAP6
gene id: 29088:PGAP6
uniprot id: A0A8M1MKX3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:GPR155
gene id: 29088:GPR155
uniprot id: A0A2Y9I428
names: Subcellular Location Annotation
messages: Membrane

29088:TTYH2
gene id: 29088:TTYH2
uniprot id: A0A2Y9G8Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

29088:PROKR2
gene id: 29088:PROKR2
uniprot id: A0A2Y9H050
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:TATDN1
gene id: 29088:TATDN1
uniprot id: A0A2Y9GYZ0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

29088:LOC110591119
gene id: 29088:LOC110591119
uniprot id: A0A2Y9I1M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

29088:ZIC3
gene id: 29088:ZIC3
uniprot id: A0A2Y9GM60
uniprot id: A0A2Y9GM97
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

29088:GRID2
gene id: 29088:GRID2
uniprot id: A0A8M1M8L8
uniprot id: A0A8M1MCR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

29088:MAGOH
gene id: 29088:MAGOH
uniprot id: A0A2Y9GQJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

29088:RELT
gene id: 29088:RELT
uniprot id: A0A2Y9IDB0
names: Similarity
messages: Belongs to the RELT family.

29088:EPS8L2
gene id: 29088:EPS8L2
uniprot id: A0A2Y9H8C9
uniprot id: A0A8M1MPI8
names: Similarity
messages: Belongs to the EPS8 family.

29088:CER1
gene id: 29088:CER1
uniprot id: A0A2Y9GG82
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:CKAP5
gene id: 29088:CKAP5
uniprot id: A0A2Y9GP85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOG/XMAP215 family.
messages: kinetochore

29088:LOC110581805
gene id: 29088:LOC110581805
uniprot id: A0A2Y9HCC7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:BBS2
gene id: 29088:BBS2
uniprot id: A0A2Y9IGB6
names: Subcellular Location Annotation
messages: centriolar satellite
messages: cilium membrane

29088:KCNS2
gene id: 29088:KCNS2
uniprot id: A0A2Y9GYP1
names: Subcellular Location Annotation
messages: Membrane

29088:RIPPLY1
gene id: 29088:RIPPLY1
uniprot id: A0A2Y9G5D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

29088:HSD17B12
gene id: 29088:HSD17B12
uniprot id: A0A2Y9GT88
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29088:CENPT
gene id: 29088:CENPT
uniprot id: A0A2Y9I5W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-T/CNN1 family.
messages: Nucleus
messages: kinetochore

29088:NTN4
gene id: 29088:NTN4
uniprot id: A0A2Y9GVH5
uniprot id: A0A2Y9GZF9
uniprot id: A0A2Y9H193
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:TFE3
gene id: 29088:TFE3
uniprot id: A0A8M1M4K3
uniprot id: A0A8M1M9X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

29088:ADAM15
gene id: 29088:ADAM15
uniprot id: A0A2Y9GF99
uniprot id: A0A2Y9GFA5
uniprot id: A0A2Y9GFF3
uniprot id: A0A2Y9GFF8
uniprot id: A0A2Y9GFG8
uniprot id: A0A2Y9GIK9
uniprot id: A0A2Y9GIM6
uniprot id: A0A2Y9GIN2
uniprot id: A0A2Y9GK43
uniprot id: A0A2Y9GK49
uniprot id: A0A8M1MLT6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:KRT23
gene id: 29088:KRT23
uniprot id: A0A2Y9IBH1
uniprot id: A0A8M1MX18
names: Similarity
messages: Belongs to the intermediate filament family.

29088:KBTBD8
gene id: 29088:KBTBD8
uniprot id: A0A2Y9HGN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KBTBD8 family.
messages: Golgi apparatus
messages: spindle

29088:CC2D1B
gene id: 29088:CC2D1B
uniprot id: A0A2Y9GRQ4
names: Similarity
messages: Belongs to the CC2D1 family.

29088:PTPN11
gene id: 29088:PTPN11
uniprot id: A0A2Y9HW85
uniprot id: A0A2Y9HXT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

29088:HSD3B2
gene id: 29088:HSD3B2
uniprot id: A0A2Y9H7N6
names: Similarity
messages: Belongs to the 3-beta-HSD family.

29088:NOTCH1
gene id: 29088:NOTCH1
uniprot id: A0A2Y9H548
uniprot id: A0A2Y9H551
uniprot id: A0A2Y9HAI0
uniprot id: A0A2Y9HBV2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

29088:SS18L1
gene id: 29088:SS18L1
uniprot id: A0A2Y9G6X2
names: Similarity
messages: Belongs to the SS18 family.

29088:TTC3
gene id: 29088:TTC3
uniprot id: A0A2Y9G3Z2
uniprot id: A0A2Y9G4F0
uniprot id: A0A2Y9G6F9
uniprot id: A0A8M1MXA5
names: Subcellular Location Annotation
messages: Cytoplasm

29088:S100A16
gene id: 29088:S100A16
uniprot id: A0A2Y9GFG9
names: Similarity
messages: Belongs to the S-100 family.

29088:B3GNT3
gene id: 29088:B3GNT3
uniprot id: A0A2Y9GNH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:PSMB10
gene id: 29088:PSMB10
uniprot id: A0A2Y9I5F1
uniprot id: A0A2Y9IA92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

29088:TMEM47
gene id: 29088:TMEM47
uniprot id: A0A2Y9GDS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

29088:LOC110584713
gene id: 29088:LOC110584713
uniprot id: A0A2Y9HFJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

29088:ATP5F1A
gene id: 29088:ATP5F1A
uniprot id: A0A2Y9GVX5
uniprot id: A0A8M1MSJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

29088:KCNQ2
gene id: 29088:KCNQ2
uniprot id: A0A8M1MWK8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:KMT2B
gene id: 29088:KMT2B
uniprot id: A0A2Y9HXS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
messages: Nucleus

29088:LRRC8C
gene id: 29088:LRRC8C
uniprot id: A0A2Y9H2H3
uniprot id: A0A2Y9H2L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

29088:HMX1
gene id: 29088:HMX1
uniprot id: A0A2Y9G2P1
names: Subcellular Location Annotation
messages: Nucleus

29088:CCN5
gene id: 29088:CCN5
uniprot id: A0A2Y9H6C2
names: Similarity
messages: Belongs to the CCN family.

29088:ACOX3
gene id: 29088:ACOX3
uniprot id: A0A2Y9G2R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

29088:SNX18
gene id: 29088:SNX18
uniprot id: A0A2Y9HRZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

29088:POU2F3
gene id: 29088:POU2F3
uniprot id: A0A2Y9HJY9
uniprot id: A0A2Y9HRC6
uniprot id: A0A8M1MPZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus

29088:DENND6A
gene id: 29088:DENND6A
uniprot id: A0A2Y9HMH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Recycling endosome

29088:LOC110587676
gene id: 29088:LOC110587676
uniprot id: A0A8M1M6H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL42 family.
messages: Mitochondrion

29088:ITIH4
gene id: 29088:ITIH4
uniprot id: A0A2Y9HMW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

29088:LOC110580946
gene id: 29088:LOC110580946
uniprot id: A0A2Y9H3W7
names: Subcellular Location Annotation
messages: Membrane

29088:RPL34
gene id: 29088:RPL34
uniprot id: A0A2Y9GSB1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

29088:DHH
gene id: 29088:DHH
uniprot id: A0A2Y9IDV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

29088:RARRES1
gene id: 29088:RARRES1
uniprot id: A0A2Y9I9V9
uniprot id: A0A8M1MB14
names: Similarity
messages: Belongs to the protease inhibitor I47 (latexin) family.

29088:KCNAB2
gene id: 29088:KCNAB2
uniprot id: A0A8M1M7E6
uniprot id: A0A8M1M7N8
uniprot id: A0A8M1MB84
uniprot id: A0A8M1MFQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: axon
messages: cytoskeleton
messages: synaptosome

29088:NAPEPLD
gene id: 29088:NAPEPLD
uniprot id: A0A2Y9H824
uniprot id: A0A8M1MTM5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPE-PLD family.
messages: Binds 2 zinc divalent cations per subunit.
messages: Homodimer. Bile acids promote the assembly of inactive monomers into an active dimer and enable catalysis.
messages: Nucleus envelope

29088:SPCS2
gene id: 29088:SPCS2
uniprot id: A0A2Y9I8S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS2 family.
messages: Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:LOC110587566
gene id: 29088:LOC110587566
uniprot id: A0A2Y9HUA0
names: Similarity
messages: Belongs to the SNF7 family.

29088:MAST4
gene id: 29088:MAST4
uniprot id: A0A2Y9I826
uniprot id: A0A8M1MG27
uniprot id: A0A8M1MG31
uniprot id: A0A8M1MI58
uniprot id: A0A8M1MPW2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

29088:KRT84
gene id: 29088:KRT84
uniprot id: A0A2Y9GYK4
names: Similarity
messages: Belongs to the intermediate filament family.

29088:LOC110590886
gene id: 29088:LOC110590886
uniprot id: A0A8M1M6L8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

29088:DDX1
gene id: 29088:DDX1
uniprot id: A0A2Y9HUF0
uniprot id: A0A8M1MW15
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX1 subfamily.
messages: Cytoplasmic granule
messages: RNA helicase.
messages: The helicase domain is involved in the stimulation of RELA transcriptional activity.

29088:LOC110581176
gene id: 29088:LOC110581176
uniprot id: A0A2Y9H4Q4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:BOP1
gene id: 29088:BOP1
uniprot id: A0A8M1M9U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat BOP1/ERB1 family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

29088:ACAD11
gene id: 29088:ACAD11
uniprot id: A0A8M1MG56
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

29088:AZIN2
gene id: 29088:AZIN2
uniprot id: A0A2Y9GJL2
uniprot id: A0A8M1M7Q1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

29088:SOX3
gene id: 29088:SOX3
uniprot id: A0A2Y9GLX0
uniprot id: A0A2Y9GM76
names: Subcellular Location Annotation
messages: Nucleus

29088:PADI4
gene id: 29088:PADI4
uniprot id: A0A2Y9GJ29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

29088:SLC30A10
gene id: 29088:SLC30A10
uniprot id: A0A2Y9HQV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

29088:SCD5
gene id: 29088:SCD5
uniprot id: A0A2Y9I723
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

29088:ARL2
gene id: 29088:ARL2
uniprot id: A0A2Y9GN60
uniprot id: A0A8M1MX98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

29088:SLC39A5
gene id: 29088:SLC39A5
uniprot id: A0A2Y9H068
names: Subcellular Location Annotation
messages: Membrane

29088:RECQL4
gene id: 29088:RECQL4
uniprot id: A0A2Y9H2M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

29088:DAD1
gene id: 29088:DAD1
uniprot id: A0A2Y9HGX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

29088:LOC110570367
gene id: 29088:LOC110570367
uniprot id: A0A8M1MV95
names: Subcellular Location Annotation
messages: Membrane

29088:HTR2B
gene id: 29088:HTR2B
uniprot id: A0A2Y9H343
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: synaptosome

29088:LOC110574245
gene id: 29088:LOC110574245
uniprot id: A0A8M1MTP8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

29088:MOCOS
gene id: 29088:MOCOS
uniprot id: A0A2Y9GRD1
uniprot id: A0A2Y9GRF9
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
messages: Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.

29088:DCAF13
gene id: 29088:DCAF13
uniprot id: A0A2Y9H3Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

29088:TAF11
gene id: 29088:TAF11
uniprot id: A0A2Y9GM16
uniprot id: A0A2Y9GMA9
names: Similarity
messages: Belongs to the TAF11 family.

29088:EBPL
gene id: 29088:EBPL
uniprot id: A0A2Y9H765
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:TSHZ1
gene id: 29088:TSHZ1
uniprot id: A0A2Y9GVP3
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

29088:CACNB1
gene id: 29088:CACNB1
uniprot id: A0A2Y9I7N2
uniprot id: A0A2Y9I8G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Membrane
messages: sarcolemma

29088:PTGIS
gene id: 29088:PTGIS
uniprot id: A0A2Y9GQM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

29088:FANCC
gene id: 29088:FANCC
uniprot id: A0A8M1MRR0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. This complex may also include HSP70.
messages: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
messages: Nucleus

29088:KIF13B
gene id: 29088:KIF13B
uniprot id: A0A8M1M6Z5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:TPRKB
gene id: 29088:TPRKB
uniprot id: A0A2Y9HZT6
uniprot id: A0A8M1MLG0
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

29088:AGO2
gene id: 29088:AGO2
uniprot id: A0A2Y9H5D8
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argonaute family. Ago subfamily.
messages: Hydroxylated. 4-hydroxylation appears to enhance protein stability but is not required for miRNA-binding or endonuclease activity.
messages: Interacts with DICER1 through its Piwi domain and with TARBP2 during assembly of the RNA-induced silencing complex (RISC). Together, DICER1, AGO2 and TARBP2 constitute the trimeric RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC). Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. Note however that the term RISC has also been used to describe the trimeric RLC/miRLC. The formation of RISC complexes containing siRNAs rather than miRNAs appears to occur independently of DICER1. Interacts with AGO1. Also interacts with DDB1, DDX5, DDX6, DDX20, DHX30, DHX36, DDX47, DHX9, ELAVL, FXR1, GEMIN4, HNRNPF, IGF2BP1, ILF3, IMP8, MATR3, PABPC1, PRMT5, P4HA1, P4HB, RBM4, SART3, TNRC6A, TNRC6B, UPF1 and YBX1. Interacts with the P-body components DCP1A and XRN1. Associates with polysomes and messenger ribonucleoproteins (mNRPs). Interacts with RBM4; the interaction is modulated under stress-induced conditions, occurs under both cell proliferation and differentiation conditions and in an RNA-and phosphorylation-independent manner. Interacts with LIMD1, WTIP and AJUBA. Interacts with TRIM71. Interacts with APOBEC3G in an RNA-dependent manner. Interacts with APOBEC3A, APOBEC3C, APOBEC3F and APOBEC3H. Interacts with DICER1, TARBP2, EIF6, MOV10 and RPL7A (60S ribosome subunit); they form a large RNA-induced silencing complex (RISC). Interacts with FMR1. Interacts with ZFP36.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the mRNA specifically by AGO2. Binding of RISC to a partially complementary mRNA results in silencing through inhibition of translation, and this is independent of endonuclease activity. May inhibit translation initiation by binding to the 7-methylguanosine cap, thereby preventing the recruitment of the translation initiation factor eIF4-E. May also inhibit translation initiation via interaction with EIF6, which itself binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit. The inhibition of translational initiation leads to the accumulation of the affected mRNA in cytoplasmic processing bodies (P-bodies), where mRNA degradation may subsequently occur. In some cases RISC-mediated translational repression is also observed for miRNAs that perfectly match the 3' untranslated region (3'-UTR). Can also up-regulate the translation of specific mRNAs under certain growth conditions. Binds to the AU element of the 3'-UTR of the TNF (TNF-alpha) mRNA and up-regulates translation under conditions of serum starvation. Also required for transcriptional gene silencing (TGS), in which short RNAs known as antigene RNAs or agRNAs direct the transcriptional repression of complementary promoter regions.
messages: The Piwi domain may perform RNA cleavage by a mechanism similar to that of RNase H. However, while RNase H utilizes a triad of Asp-Asp-Glu (DDE) for metal ion coordination, this protein appears to utilize a triad of Asp-Asp-His (DDH).

29088:LOC110583428
gene id: 29088:LOC110583428
uniprot id: A0A8M1MRS7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

29088:LOC110577726
gene id: 29088:LOC110577726
uniprot id: A0A8M1MJ63
names: Similarity
messages: Belongs to the SELO family.

29088:LYRM9
gene id: 29088:LYRM9
uniprot id: A0A2Y9IF49
names: Similarity
messages: Belongs to the complex I LYR family. LYRM9 subfamily.

29088:DAG1
gene id: 29088:DAG1
uniprot id: A0A2Y9GTG4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
messages: Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
messages: cytoskeleton
messages: extracellular space
messages: nucleoplasm
messages: sarcolemma

29088:PGLYRP1
gene id: 29088:PGLYRP1
uniprot id: A0A2Y9GH77
names: Function
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
messages: Innate immunity protein that plays several important functions in antimicrobial and antitumor defense systems.

29088:LOC110587929
gene id: 29088:LOC110587929
uniprot id: A0A2Y9HVA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion
messages: Mitochondrion inner membrane

29088:DNAJB14
gene id: 29088:DNAJB14
uniprot id: A0A2Y9GAN7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:PDE7B
gene id: 29088:PDE7B
uniprot id: A0A2Y9HBI9
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

29088:TADA2A
gene id: 29088:TADA2A
uniprot id: A0A2Y9I7H0
uniprot id: A0A2Y9I7S4
names: Subcellular Location Annotation
messages: Nucleus

29088:LYN
gene id: 29088:LYN
uniprot id: A0A2Y9GY53
uniprot id: A0A8M1M9V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

29088:NR4A2
gene id: 29088:NR4A2
uniprot id: A0A2Y9I8K9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Interacts with SFPQ, NCOR2, SIN3A and HADC1. The interaction with NCOR2 increases in the absence of PITX3. Interacts with PER2.
messages: Nucleus

29088:LOC110583444
gene id: 29088:LOC110583444
uniprot id: A0A2Y9GS66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Inhibitor of PPP1CA.
messages: Membrane

29088:TIMM9
gene id: 29088:TIMM9
uniprot id: A0A2Y9HZT7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

29088:KLC4
gene id: 29088:KLC4
uniprot id: A0A2Y9H7A6
uniprot id: A0A8M1MK53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

29088:LOC110593661
gene id: 29088:LOC110593661
uniprot id: A0A8M1MAJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRB/QCR7 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

29088:BABAM2
gene id: 29088:BABAM2
uniprot id: A0A2Y9HMP3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BABAM2 family.
messages: Component of the ARISC complex. Component of the BRCA1-A complex. Component of the BRISC complex. Binds polyubiquitin.
messages: Contains 2 ubiquitin-conjugating enzyme family-like (UEV-like) regions. These regions lack the critical Cys residues required for ubiquitination but retain the ability to bind ubiquitin.
messages: Cytoplasm
messages: May play a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins. May also act as a death receptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway.
messages: Nucleus

29088:CHD6
gene id: 29088:CHD6
uniprot id: A0A2Y9H3Q4
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

29088:NEFH
gene id: 29088:NEFH
uniprot id: A0A2Y9I6D3
names: Similarity
messages: Belongs to the intermediate filament family.

29088:LOC110584951
gene id: 29088:LOC110584951
uniprot id: A0A8M1MHT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

29088:IL7
gene id: 29088:IL7
uniprot id: A0A2Y9GY68
uniprot id: A0A2Y9H2R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-7/IL-9 family.
messages: Hematopoietic cytokine that plays an essential role in the development, expansion, and survival of naive and memory T-cells and B-cells thereby regulating the number of mature lymphocytes and maintaining lymphoid homeostasis.
messages: Secreted

29088:CA7
gene id: 29088:CA7
uniprot id: A0A2Y9IBR8
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

29088:MARCKSL1
gene id: 29088:MARCKSL1
uniprot id: A0A2Y9GL12
names: Similarity
messages: Belongs to the MARCKS family.

29088:LOC110575596
gene id: 29088:LOC110575596
uniprot id: A0A2Y9GQY4
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

29088:MEAF6
gene id: 29088:MEAF6
uniprot id: A0A2Y9GJN3
uniprot id: A0A8M1M7R5
uniprot id: A0A8M1MA61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF6 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
messages: Component of the NuA4 histone acetyltransferase complex. Component of the hbo1 complex. Component of the moz/morf complex.
messages: kinetochore
messages: nucleolus

29088:KIF1A
gene id: 29088:KIF1A
uniprot id: A0A2Y9G6M2
uniprot id: A0A2Y9G6Z8
uniprot id: A0A2Y9G931
uniprot id: A0A2Y9G936
uniprot id: A0A2Y9GA64
uniprot id: A0A8M1M6B3
uniprot id: A0A8M1M6B8
uniprot id: A0A8M1M6L6
uniprot id: A0A8M1M6M1
uniprot id: A0A8M1M8R1
uniprot id: A0A8M1M8R6
uniprot id: A0A8M1MA50
uniprot id: A0A8M1MA55
uniprot id: A0A8M1MA60
uniprot id: A0A8M1MEH8
uniprot id: A0A8M1MEI4
uniprot id: A0A8M1MEJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: axon

29088:CDCA8
gene id: 29088:CDCA8
uniprot id: A0A2Y9GJY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the borealin family.
messages: centromere

29088:SDHAF2
gene id: 29088:SDHAF2
uniprot id: A0A2Y9GMU9
uniprot id: A0A2Y9GTJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with SDHA within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.

29088:TIMP2
gene id: 29088:TIMP2
uniprot id: A0A2Y9GC89
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

29088:REEP1
gene id: 29088:REEP1
uniprot id: A0A8M1MQ35
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:PABPC4
gene id: 29088:PABPC4
uniprot id: A0A8M1MBK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

29088:ETV3L
gene id: 29088:ETV3L
uniprot id: A0A2Y9GEX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

29088:LOC110578447
gene id: 29088:LOC110578447
uniprot id: A0A2Y9H0S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:OSBPL2
gene id: 29088:OSBPL2
uniprot id: A0A2Y9G3D4
names: Similarity
messages: Belongs to the OSBP family.

29088:EEF2KMT
gene id: 29088:EEF2KMT
uniprot id: A0A2Y9HQ49
uniprot id: A0A2Y9HWM1
uniprot id: A0A8M1MCG6
uniprot id: A0A8M1MCL7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EEF2KMT family.

29088:AMIGO2
gene id: 29088:AMIGO2
uniprot id: A0A2Y9I9D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. AMIGO family.
messages: Cell membrane
messages: Membrane

29088:SOX12
gene id: 29088:SOX12
uniprot id: A0A2Y9GZK8
names: Subcellular Location Annotation
messages: Nucleus

29088:CCS
gene id: 29088:CCS
uniprot id: A0A2Y9GSG3
uniprot id: A0A2Y9GU42
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.

29088:DACT2
gene id: 29088:DACT2
uniprot id: A0A2Y9HBD0
names: Similarity
messages: Belongs to the dapper family.

29088:HLCS
gene id: 29088:HLCS
uniprot id: A0A8M1MEC6
names: Similarity
messages: Belongs to the biotin--protein ligase family.

29088:IP6K3
gene id: 29088:IP6K3
uniprot id: A0A2Y9GSM1
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

29088:FAM118B
gene id: 29088:FAM118B
uniprot id: A0A2Y9HKL7
names: Similarity
messages: Belongs to the FAM118 family.

29088:CTBP2
gene id: 29088:CTBP2
uniprot id: A0A2Y9I715
uniprot id: A0A2Y9IDM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

29088:LIN7C
gene id: 29088:LIN7C
uniprot id: A0A2Y9GPB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the lin-7 family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.
messages: Postsynaptic density membrane
messages: tight junction

29088:DHX29
gene id: 29088:DHX29
uniprot id: A0A2Y9I1R3
uniprot id: A0A8M1MJ89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity.
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Cytoplasm
messages: Part of the 43S pre-initiation complex (PIC) that contains at least Met-tRNA, EIF1, EIF1A (EIF1AX or EIF1AY), EIF2S1, EIF2S2, EIF2S3, EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L, EIF3M, DHX29 and the 40S ribosomal subunit.

29088:MC2R
gene id: 29088:MC2R
uniprot id: A0A2Y9GHR4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MRAP; increasing ligand-sensitivity and generation of cAMP. Interacts with MRAP2; competing with MRAP for binding to MC2R and impairing the binding of corticotropin (ACTH).
messages: Membrane

29088:NFIB
gene id: 29088:NFIB
uniprot id: A0A2Y9GG52
uniprot id: A0A2Y9GJF4
uniprot id: A0A2Y9GL43
uniprot id: A0A8M1MRE8
uniprot id: A0A8M1MRF9
uniprot id: A0A8M1MTA9
uniprot id: A0A8M1MUN6
uniprot id: A0A8M1MYI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

29088:C14H18orf32
gene id: 29088:C14H18orf32
uniprot id: A0A2Y9GRE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UPF0729 family.
messages: Interacts with DERL1 and AMFR.
messages: Lipid droplet
messages: May activate the NF-kappa-B signaling pathway.

29088:MYO1F
gene id: 29088:MYO1F
uniprot id: A0A2Y9IGV3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

29088:ARAP1
gene id: 29088:ARAP1
uniprot id: A0A2Y9IDG5
uniprot id: A0A2Y9IG95
names: Subcellular Location Annotation
messages: Cytoplasm

29088:PYGB
gene id: 29088:PYGB
uniprot id: A0A2Y9HXE2
uniprot id: A0A2Y9HXP1
uniprot id: A0A8M1MPI3
uniprot id: A0A8M1MQU2
uniprot id: A0A8M1MWR2
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

29088:CDK5
gene id: 29088:CDK5
uniprot id: A0A2Y9HGG3
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:PHF20L1
gene id: 29088:PHF20L1
uniprot id: A0A8M1MC41
uniprot id: A0A8M1MI75
names: Subcellular Location Annotation
messages: Nucleus

29088:CAMTA2
gene id: 29088:CAMTA2
uniprot id: A0A2Y9HFX0
uniprot id: A0A8M1MWX7
uniprot id: A0A8M1MZA4
names: Similarity
names: Subunit
messages: Belongs to the CAMTA family.
messages: May interact with calmodulin.

29088:CSGALNACT1
gene id: 29088:CSGALNACT1
uniprot id: A0A2Y9GIH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

29088:CALY
gene id: 29088:CALY
uniprot id: A0A8M1MIV7
names: Similarity
messages: Belongs to the NSG family.

29088:LOC110569916
gene id: 29088:LOC110569916
uniprot id: A0A2Y9H9N9
uniprot id: A0A8M1M5U3
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

29088:LOC110585078
gene id: 29088:LOC110585078
uniprot id: A0A2Y9HH05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

29088:RUNDC3B
gene id: 29088:RUNDC3B
uniprot id: A0A2Y9H1A5
uniprot id: A0A2Y9H1E1
uniprot id: A0A2Y9H1F8
uniprot id: A0A8M1MQ75
uniprot id: A0A8M1MTF9
uniprot id: A0A8M1MY89
names: Similarity
names: Subunit
messages: Belongs to the RUNDC3 family.
messages: Interacts with RAP2A.

29088:SPIRE2
gene id: 29088:SPIRE2
uniprot id: A0A2Y9IFV4
uniprot id: A0A2Y9IIY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

29088:GAS6
gene id: 29088:GAS6
uniprot id: A0A2Y9HJA0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:SLC30A7
gene id: 29088:SLC30A7
uniprot id: A0A2Y9H2X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Homooligomer.
messages: Membrane
messages: trans-Golgi network membrane

29088:LOC123325527
gene id: 29088:LOC123325527
uniprot id: A0A8M1MKE3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:PSME2
gene id: 29088:PSME2
uniprot id: A0A2Y9HPP5
uniprot id: A0A8M1MUI8
names: Similarity
messages: Belongs to the PA28 family.

29088:ATP12A
gene id: 29088:ATP12A
uniprot id: A0A2Y9G4A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Membrane

29088:TRPV6
gene id: 29088:TRPV6
uniprot id: A0A2Y9HG69
uniprot id: A0A8M1MSA7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:TRMT11
gene id: 29088:TRMT11
uniprot id: A0A2Y9HAW3
uniprot id: A0A2Y9HB80
uniprot id: A0A8M1MHG1
uniprot id: A0A8M1MHG8
names: Function
names: Subunit
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.
messages: Interacts with TRMT112.

29088:GDPGP1
gene id: 29088:GDPGP1
uniprot id: A0A2Y9GB21
uniprot id: A0A2Y9GFB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDPGP1 family.
messages: Cytoplasm
messages: Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.

29088:XPR1
gene id: 29088:XPR1
uniprot id: A0A2Y9GH14
uniprot id: A0A2Y9GH46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

29088:NUP210
gene id: 29088:NUP210
uniprot id: A0A8M1MGF1
names: Similarity
messages: Belongs to the NUP210 family.

29088:GPR158
gene id: 29088:GPR158
uniprot id: A0A2Y9H043
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:HMGCS2
gene id: 29088:HMGCS2
uniprot id: A0A2Y9H8T1
uniprot id: A0A8M1MAK4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

29088:SDR42E1
gene id: 29088:SDR42E1
uniprot id: A0A8M1MZE7
names: Similarity
messages: Belongs to the 3-beta-HSD family.

29088:TRH
gene id: 29088:TRH
uniprot id: A0A2Y9HGD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRH family.
messages: Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
messages: Secreted

29088:SETD1B
gene id: 29088:SETD1B
uniprot id: A0A2Y9HRD0
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus speckle

29088:NDUFAF4
gene id: 29088:NDUFAF4
uniprot id: A0A2Y9HI70
names: Similarity
names: Subunit
messages: Belongs to the NDUFAF4 family.
messages: Binds calmodulin. Interacts with NDUFAF3.

29088:SCRIB
gene id: 29088:SCRIB
uniprot id: A0A8M1M934
names: Similarity
messages: Belongs to the LAP (LRR and PDZ) protein family.

29088:PHOSPHO2
gene id: 29088:PHOSPHO2
uniprot id: A0A2Y9I512
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

29088:SH3BGRL3
gene id: 29088:SH3BGRL3
uniprot id: A0A2Y9GJJ3
names: Similarity
messages: Belongs to the SH3BGR family.

29088:LIPA
gene id: 29088:LIPA
uniprot id: A0A2Y9HQM8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

29088:PFN4
gene id: 29088:PFN4
uniprot id: A0A2Y9HVP0
names: Similarity
messages: Belongs to the profilin family.

29088:SEZ6L2
gene id: 29088:SEZ6L2
uniprot id: A0A2Y9HWT0
uniprot id: A0A2Y9HX00
uniprot id: A0A2Y9HX73
uniprot id: A0A2Y9I1V9
uniprot id: A0A2Y9I1W4
uniprot id: A0A2Y9I3K8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110585544
gene id: 29088:LOC110585544
uniprot id: A0A2Y9HPK5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110589053
gene id: 29088:LOC110589053
uniprot id: A0A2Y9HU67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

29088:TLE6
gene id: 29088:TLE6
uniprot id: A0A2Y9IB79
names: Similarity
messages: Belongs to the WD repeat Groucho/TLE family.

29088:RBP4
gene id: 29088:RBP4
uniprot id: A0A2Y9I013
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Interacts with TTR.
messages: Retinol-binding protein that mediates retinol transport in blood plasma.
messages: Secreted

29088:UBLCP1
gene id: 29088:UBLCP1
uniprot id: A0A2Y9HPM2
names: Subcellular Location Annotation
messages: Nucleus

29088:CD4
gene id: 29088:CD4
uniprot id: A0A2Y9H3X9
names: Subcellular Location Annotation
messages: Cell membrane

29088:FAM102A
gene id: 29088:FAM102A
uniprot id: A0A2Y9H693
uniprot id: A0A8M1MRT8
names: Similarity
messages: Belongs to the EEIG family.

29088:WASF2
gene id: 29088:WASF2
uniprot id: A0A2Y9GKU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

29088:NEU2
gene id: 29088:NEU2
uniprot id: A0A2Y9HCX5
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

29088:LOC110591123
gene id: 29088:LOC110591123
uniprot id: A0A2Y9I849
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

29088:TNNT1
gene id: 29088:TNNT1
uniprot id: A0A8M1MVR7
uniprot id: A0A8M1MVR9
uniprot id: A0A8M1MX73
uniprot id: A0A8M1MXW9
uniprot id: A0A8M1MXX0
uniprot id: A0A8M1MZD6
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

29088:INTS8
gene id: 29088:INTS8
uniprot id: A0A2Y9GYD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 8 family.
messages: Nucleus

29088:GPBP1
gene id: 29088:GPBP1
uniprot id: A0A2Y9I0M3
uniprot id: A0A2Y9I141
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

29088:USP28
gene id: 29088:USP28
uniprot id: A0A2Y9HKG8
uniprot id: A0A2Y9HR98
uniprot id: A0A8M1MP96
uniprot id: A0A8M1MPA4
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

29088:DCST2
gene id: 29088:DCST2
uniprot id: A0A2Y9GJP5
names: Subcellular Location Annotation
messages: Membrane

29088:RECQL5
gene id: 29088:RECQL5
uniprot id: A0A2Y9GF78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

29088:ABCA4
gene id: 29088:ABCA4
uniprot id: A0A2Y9H2U1
names: Subcellular Location Annotation
messages: Membrane

29088:RUNX3
gene id: 29088:RUNX3
uniprot id: A0A8M1M9Z4
names: Function
names: Subcellular Location Annotation
messages: Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
messages: Nucleus

29088:NPY5R
gene id: 29088:NPY5R
uniprot id: A0A2Y9HSS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.

29088:TAS2R1
gene id: 29088:TAS2R1
uniprot id: A0A2Y9I2X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

29088:LOC110579916
gene id: 29088:LOC110579916
uniprot id: A0A2Y9H0V5
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

29088:LOC110581175
gene id: 29088:LOC110581175
uniprot id: A0A2Y9H4R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ALG9
gene id: 29088:ALG9
uniprot id: A0A2Y9HJF9
uniprot id: A0A8M1MY10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:C3H2orf88
gene id: 29088:C3H2orf88
uniprot id: A0A2Y9I5A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small membrane AKAP family.
messages: Cell membrane
messages: Membrane

29088:GTPBP10
gene id: 29088:GTPBP10
uniprot id: A0A2Y9H663
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

29088:ARR3
gene id: 29088:ARR3
uniprot id: A0A2Y9GAG7
names: Similarity
messages: Belongs to the arrestin family.

29088:LDLRAD3
gene id: 29088:LDLRAD3
uniprot id: A0A2Y9GMZ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:KLC3
gene id: 29088:KLC3
uniprot id: A0A2Y9GD63
uniprot id: A0A2Y9GG76
uniprot id: A0A2Y9GHN8
uniprot id: A0A8M1M486
uniprot id: A0A8M1M7U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

29088:LOC110572239
gene id: 29088:LOC110572239
uniprot id: A0A2Y9GAZ6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

29088:GAP43
gene id: 29088:GAP43
uniprot id: A0A2Y9HET9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neuromodulin family.
messages: Cell membrane
messages: Cytoplasm
messages: Identified in a complex containing FGFR4, NCAM1, CDH2, PLCG1, FRS2, SRC, SHC1, GAP43 and CTTN. Interacts (via IQ domain) with calmodulin. Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence.
messages: Membrane
messages: Palmitoylated. Palmitoylation is essential for plasma membrane association.
messages: Perikaryon
messages: Synapse
messages: This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
messages: axon
messages: dendrite
messages: filopodium membrane
messages: growth cone membrane

29088:NDUFAF1
gene id: 29088:NDUFAF1
uniprot id: A0A2Y9HI15
names: Function
names: Similarity
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the CIA30 family.

29088:RPL7
gene id: 29088:RPL7
uniprot id: A0A2Y9H3K6
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

29088:POP4
gene id: 29088:POP4
uniprot id: A0A2Y9HY41
uniprot id: A0A2Y9HY74
uniprot id: A0A2Y9HYG5
uniprot id: A0A2Y9I4X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Component of nuclear RNase P and RNase MRP.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

29088:LOC110578911
gene id: 29088:LOC110578911
uniprot id: A0A8M1M8T6
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110573118
gene id: 29088:LOC110573118
uniprot id: A0A8M1M138
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

29088:SLC18B1
gene id: 29088:SLC18B1
uniprot id: A0A2Y9HB36
names: Subcellular Location Annotation
messages: Membrane

29088:HMGA1
gene id: 29088:HMGA1
uniprot id: A0A2Y9GM64
uniprot id: A0A2Y9GSV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGA family.
messages: Nucleus

29088:GCK
gene id: 29088:GCK
uniprot id: A0A2Y9I688
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hexokinase family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: cytosol

29088:DLL1
gene id: 29088:DLL1
uniprot id: A0A2Y9HB84
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

29088:TMEM201
gene id: 29088:TMEM201
uniprot id: A0A2Y9GP44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM201 family.
messages: Membrane
messages: Nucleus inner membrane

29088:ZACN
gene id: 29088:ZACN
uniprot id: A0A2Y9GBU4
names: Subcellular Location Annotation
messages: Membrane

29088:CUL1
gene id: 29088:CUL1
uniprot id: A0A2Y9HAC5
uniprot id: A0A2Y9HH41
names: Similarity
messages: Belongs to the cullin family.

29088:TCP11L1
gene id: 29088:TCP11L1
uniprot id: A0A2Y9GMD5
names: Similarity
messages: Belongs to the TCP11 family.

29088:LOC110570778
gene id: 29088:LOC110570778
uniprot id: A0A2Y9G636
uniprot id: A0A2Y9G637
names: Subcellular Location Annotation
messages: Peroxisome

29088:TMEM255A
gene id: 29088:TMEM255A
uniprot id: A0A2Y9GR80
uniprot id: A0A2Y9GWY0
uniprot id: A0A2Y9GWZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

29088:ANO8
gene id: 29088:ANO8
uniprot id: A0A2Y9GI93
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:LOC110591613
gene id: 29088:LOC110591613
uniprot id: A0A8M1MPB9
names: Subcellular Location Annotation
messages: Membrane

29088:IMP3
gene id: 29088:IMP3
uniprot id: A0A2Y9HD32
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

29088:LOC110581512
gene id: 29088:LOC110581512
uniprot id: A0A2Y9H5Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ABRAXAS1
gene id: 29088:ABRAXAS1
uniprot id: A0A2Y9I6Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM175 family. Abraxas subfamily.
messages: Nucleus

29088:LOC110580231
gene id: 29088:LOC110580231
uniprot id: A0A2Y9H6U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:POU3F4
gene id: 29088:POU3F4
uniprot id: A0A2Y9HB81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

29088:ELOA
gene id: 29088:ELOA
uniprot id: A0A8M1M9R0
names: Subcellular Location Annotation
messages: Nucleus

29088:SOSTDC1
gene id: 29088:SOSTDC1
uniprot id: A0A2Y9H1D2
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ZFP36L1
gene id: 29088:ZFP36L1
uniprot id: A0A2Y9GCB8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

29088:GMPR2
gene id: 29088:GMPR2
uniprot id: A0A2Y9HHI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

29088:PAFAH1B1
gene id: 29088:PAFAH1B1
uniprot id: A0A2Y9I8T3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Can self-associate. Interacts with DCX, dynein, dynactin, IQGAP1, KATNB1, NDE1, NDEL1, NUDC and RSN. Interacts with DISC1, and this interaction is enhanced by NDEL1. Interacts with DAB1 when DAB1 is phosphorylated in response to RELN/reelin signaling. Component of cytosolic PAF-AH IB, which is composed of PAFAH1B1 (alpha), PAFAH1B2 (beta) and PAFAH1B3 (gamma) subunits. Trimer formation is not essential for the catalytic activity of the enzyme which is contributed solely by the PAFAH1B2 (beta) and PAFAH1B3 (gamma) subunits.
messages: Dimerization mediated by the LisH domain may be required to activate dynein.
messages: Nucleus membrane
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Neuronal migration involves a process called nucleokinesis, whereby migrating cells extend an anterior process into which the nucleus subsequently translocates. During nucleokinesis dynein at the nuclear surface may translocate the nucleus towards the centrosome by exerting force on centrosomal microtubules. Also required for proper activation of Rho GTPases and actin polymerization at the leading edge of locomoting cerebellar neurons and postmigratory hippocampal neurons in response to calcium influx triggered via NMDA receptors. May also play a role in other forms of cell locomotion including the migration of fibroblasts during wound healing. Non-catalytic subunit of an acetylhydrolase complex which inactivates platelet-activating factor (PAF) by removing the acetyl group at the SN-2 position.
messages: centrosome
messages: cytoskeleton
messages: spindle

29088:ATP6V0A4
gene id: 29088:ATP6V0A4
uniprot id: A0A2Y9HA77
uniprot id: A0A8M1MQQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

29088:KCNS3
gene id: 29088:KCNS3
uniprot id: A0A2Y9HTG3
names: Subcellular Location Annotation
messages: Membrane

29088:ZSCAN26
gene id: 29088:ZSCAN26
uniprot id: A0A8M1MHR5
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110573351
gene id: 29088:LOC110573351
uniprot id: A0A2Y9GJ62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:PTPRK
gene id: 29088:PTPRK
uniprot id: A0A8M1MHY0
uniprot id: A0A8M1MK08
uniprot id: A0A8M1MLB5
uniprot id: A0A8M1MRW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

29088:LOC110585327
gene id: 29088:LOC110585327
uniprot id: A0A2Y9HHU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:TTC27
gene id: 29088:TTC27
uniprot id: A0A2Y9HTD2
names: Similarity
messages: Belongs to the TTC27 family.

29088:NMT1
gene id: 29088:NMT1
uniprot id: A0A2Y9GEC0
uniprot id: A0A2Y9GHG2
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

29088:PABIR2
gene id: 29088:PABIR2
uniprot id: A0A2Y9GLE5
uniprot id: A0A2Y9GRW7
uniprot id: A0A8M1M0S8
uniprot id: A0A8M1M0T3
uniprot id: A0A8M1M136
uniprot id: A0A8M1M141
uniprot id: A0A8M1M3C0
uniprot id: A0A8M1M3C5
uniprot id: A0A8M1M4W0
uniprot id: A0A8M1M4W5
uniprot id: A0A8M1M8K0
uniprot id: A0A8M1M8K5
uniprot id: A0A8M1M8K9
names: Similarity
messages: Belongs to the FAM122 family.

29088:NKAIN1
gene id: 29088:NKAIN1
uniprot id: A0A2Y9GPP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

29088:KCNJ10
gene id: 29088:KCNJ10
uniprot id: A0A2Y9GEQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

29088:TNNT2
gene id: 29088:TNNT2
uniprot id: A0A2Y9GK89
uniprot id: A0A2Y9GLX9
uniprot id: A0A8M1MGY0
uniprot id: A0A8M1MM08
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

29088:LOC110582425
gene id: 29088:LOC110582425
uniprot id: A0A2Y9HEL5
uniprot id: A0A8M1MP02
uniprot id: A0A8M1MP12
uniprot id: A0A8M1MQX2
uniprot id: A0A8M1MSA0
uniprot id: A0A8M1MXQ6
uniprot id: A0A8M1MXQ8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with UHRF2/NIRF.
messages: May be involved in cell cycle regulation.
messages: Nucleus

29088:PAQR3
gene id: 29088:PAQR3
uniprot id: A0A2Y9I9D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

29088:LOC110580904
gene id: 29088:LOC110580904
uniprot id: A0A8M1MAN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

29088:ANKS1B
gene id: 29088:ANKS1B
uniprot id: A0A2Y9GUP1
uniprot id: A0A2Y9GUP6
uniprot id: A0A2Y9GUQ1
uniprot id: A0A2Y9GUV3
uniprot id: A0A2Y9GUX9
uniprot id: A0A2Y9GUY6
uniprot id: A0A2Y9GYY9
uniprot id: A0A2Y9GYZ4
uniprot id: A0A2Y9H0P2
uniprot id: A0A2Y9H0P8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

29088:LOC110580499
gene id: 29088:LOC110580499
uniprot id: A0A2Y9H7Q2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

29088:TMEM214
gene id: 29088:TMEM214
uniprot id: A0A2Y9HMR5
uniprot id: A0A8M1MN04
uniprot id: A0A8M1MPA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TMEM214 family.
messages: Constitutively interacts with CASP4; required for the localization of procaspase 4 to the ER.
messages: Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:SHMT1
gene id: 29088:SHMT1
uniprot id: A0A2Y9HEG8
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

29088:SLC27A6
gene id: 29088:SLC27A6
uniprot id: A0A2Y9I1D5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

29088:RNF20
gene id: 29088:RNF20
uniprot id: A0A2Y9H6V0
uniprot id: A0A2Y9H714
uniprot id: A0A8M1MU21
uniprot id: A0A8M1MYN7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BRE1 family.
messages: Component of the RNF20/40 complex (also known as BRE1 complex) probably composed of 2 copies of RNF20/BRE1A and 2 copies of RNF40/BRE1B. Interacts with UBE2E1/UBCH6.
messages: Nucleus

29088:IDH3B
gene id: 29088:IDH3B
uniprot id: A0A2Y9GZP9
uniprot id: A0A2Y9GZW3
uniprot id: A0A8M1MNY9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

29088:CHM
gene id: 29088:CHM
uniprot id: A0A2Y9HCP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.

29088:LOC110589792
gene id: 29088:LOC110589792
uniprot id: A0A2Y9I1P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

29088:NEK6
gene id: 29088:NEK6
uniprot id: A0A8M1MSE0
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:CHD1L
gene id: 29088:CHD1L
uniprot id: A0A8M1M867
uniprot id: A0A8M1M8F4
uniprot id: A0A8M1MAK9
uniprot id: A0A8M1MBY9
uniprot id: A0A8M1MGI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

29088:GCG
gene id: 29088:GCG
uniprot id: A0A2Y9I4H7
uniprot id: A0A2Y9I553
names: Similarity
messages: Belongs to the glucagon family.

29088:SENP8
gene id: 29088:SENP8
uniprot id: A0A2Y9HD73
names: Similarity
messages: Belongs to the peptidase C48 family.

29088:AK5
gene id: 29088:AK5
uniprot id: A0A2Y9G6M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylate kinase family.
messages: Cytoplasm

29088:TMEM184B
gene id: 29088:TMEM184B
uniprot id: A0A8M1MDX5
names: Subcellular Location Annotation
messages: Membrane

29088:SLC44A1
gene id: 29088:SLC44A1
uniprot id: A0A2Y9H573
uniprot id: A0A2Y9HAK9
uniprot id: A0A2Y9HBX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

29088:CCL20
gene id: 29088:CCL20
uniprot id: A0A2Y9GHL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

29088:RGS2
gene id: 29088:RGS2
uniprot id: A0A2Y9GSN1
uniprot id: A0A2Y9GSZ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: nucleolus

29088:CAD
gene id: 29088:CAD
uniprot id: A0A2Y9HV10
uniprot id: A0A8M1MNK4
names: Similarity
messages: In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.

29088:IL1B
gene id: 29088:IL1B
uniprot id: A0A2Y9HMN5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-1 family.
messages: IL1B production occurs in 2 steps, each being controlled by different stimuli. First, inflammatory signals, such as LPS, stimulate the synthesis and promote the accumulation of cytosolic stores of pro-IL1B (priming). Then additional signals are required for inflammasome assembly, leading to CASP1 activation, pro-IL1B processing and eventually secretion of the active cytokine. IL1B processing and secretion are temporarily associated.
messages: Lysosome
messages: Monomer. Interacts with MEFV.
messages: Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
messages: Secreted
messages: cytosol
messages: extracellular exosome

29088:KRTCAP2
gene id: 29088:KRTCAP2
uniprot id: A0A2Y9GF17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRTCAP2 family.
messages: Membrane

29088:BLOC1S6
gene id: 29088:BLOC1S6
uniprot id: A0A2Y9HH29
names: Function
names: Similarity
messages: Belongs to the BLOC1S6 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process.

29088:SEPSECS
gene id: 29088:SEPSECS
uniprot id: A0A2Y9GAD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepSecS family.
messages: Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homotetramer formed by a catalytic dimer and a non-catalytic dimer serving as a binding platform that orients tRNASec for catalysis. Each tetramer binds the CCA ends of two tRNAs which point to the active sites of the catalytic dimer.

29088:PPP1R11
gene id: 29088:PPP1R11
uniprot id: A0A2Y9HSD5
names: Subunit
messages: Interacts with TLR2 and UBE2D2.

29088:SLC25A45
gene id: 29088:SLC25A45
uniprot id: A0A2Y9GNB6
uniprot id: A0A8M1MNL7
uniprot id: A0A8M1MQJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:JAKMIP1
gene id: 29088:JAKMIP1
uniprot id: A0A2Y9G2H3
uniprot id: A0A2Y9G2M7
uniprot id: A0A2Y9G538
uniprot id: A0A2Y9G674
names: Similarity
messages: Belongs to the JAKMIP family.

29088:RSPO3
gene id: 29088:RSPO3
uniprot id: A0A2Y9HID2
names: Similarity
messages: Belongs to the R-spondin family.

29088:PRIM2
gene id: 29088:PRIM2
uniprot id: A0A2Y9H7H4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.

29088:CNOT2
gene id: 29088:CNOT2
uniprot id: A0A2Y9G5N0
uniprot id: A0A2Y9G5N2
uniprot id: A0A2Y9G846
uniprot id: A0A2Y9G991
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

29088:LOC110585751
gene id: 29088:LOC110585751
uniprot id: A0A8M1M5P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

29088:GUCY1B1
gene id: 29088:GUCY1B1
uniprot id: A0A8M1M691
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

29088:TNFRSF1B
gene id: 29088:TNFRSF1B
uniprot id: A0A2Y9GIY2
uniprot id: A0A2Y9GJ81
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:KIF27
gene id: 29088:KIF27
uniprot id: A0A2Y9G3J3
uniprot id: A0A8M1MR54
uniprot id: A0A8M1MR62
uniprot id: A0A8M1MUD9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:LOC110570105
gene id: 29088:LOC110570105
uniprot id: A0A2Y9G3Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGP family.
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

29088:DLX4
gene id: 29088:DLX4
uniprot id: A0A2Y9I7X4
uniprot id: A0A8M1MUT4
names: Subcellular Location Annotation
messages: Nucleus

29088:DOP1A
gene id: 29088:DOP1A
uniprot id: A0A8M1MI85
uniprot id: A0A8M1MI86
uniprot id: A0A8M1MKA6
uniprot id: A0A8M1MLM0
uniprot id: A0A8M1MS76
names: Similarity
messages: Belongs to the dopey family.

29088:PTPN2
gene id: 29088:PTPN2
uniprot id: A0A2Y9GHQ9
uniprot id: A0A2Y9GHT3
uniprot id: A0A2Y9GHW7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

29088:AGT
gene id: 29088:AGT
uniprot id: A0A2Y9HJK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family.
messages: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.
messages: Secreted
messages: Stimulates aldosterone release.

29088:CAPN11
gene id: 29088:CAPN11
uniprot id: A0A2Y9H7Z4
names: Similarity
messages: Belongs to the peptidase C2 family.

29088:SEC62
gene id: 29088:SEC62
uniprot id: A0A2Y9I2Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC62 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:CDR2
gene id: 29088:CDR2
uniprot id: A0A2Y9GTG5
names: Similarity
messages: Belongs to the CDR2 family.

29088:LOC110589307
gene id: 29088:LOC110589307
uniprot id: A0A2Y9HUV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

29088:GALNT15
gene id: 29088:GALNT15
uniprot id: A0A2Y9G618
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

29088:PDP1
gene id: 29088:PDP1
uniprot id: A0A2Y9GXF6
uniprot id: A0A8M1MCB7
names: Similarity
messages: Belongs to the PP2C family.

29088:FAM151B
gene id: 29088:FAM151B
uniprot id: A0A2Y9I1G1
names: Similarity
messages: Belongs to the FAM151 family.

29088:MTMR10
gene id: 29088:MTMR10
uniprot id: A0A8M1MK64
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

29088:MED19
gene id: 29088:MED19
uniprot id: A0A2Y9GMU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

29088:TRAPPC13
gene id: 29088:TRAPPC13
uniprot id: A0A2Y9I0I5
uniprot id: A0A2Y9I0U4
uniprot id: A0A2Y9I0U9
uniprot id: A0A2Y9I105
uniprot id: A0A2Y9I5H4
uniprot id: A0A2Y9I5I0
uniprot id: A0A2Y9I7G8
names: Similarity
names: Subunit
messages: Belongs to the TRAPPC13 family.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.

29088:FAM114A1
gene id: 29088:FAM114A1
uniprot id: A0A2Y9I095
uniprot id: A0A2Y9I4X8
uniprot id: A0A8M1M488
names: Similarity
messages: Belongs to the FAM114 family.

29088:DLC1
gene id: 29088:DLC1
uniprot id: A0A2Y9HK42
uniprot id: A0A2Y9HKE7
uniprot id: A0A8M1M4R6
names: Subcellular Location Annotation
messages: Cytoplasm

29088:CUL9
gene id: 29088:CUL9
uniprot id: A0A8M1MJF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cullin family.
messages: Cytoplasm

29088:SEMA6B
gene id: 29088:SEMA6B
uniprot id: A0A8M1MIY4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ZNF408
gene id: 29088:ZNF408
uniprot id: A0A2Y9GT94
names: Subcellular Location Annotation
messages: Nucleus

29088:TDGF1
gene id: 29088:TDGF1
uniprot id: A0A2Y9GZW7
names: Caution
names: Similarity
messages: Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:TAF5L
gene id: 29088:TAF5L
uniprot id: A0A2Y9HQR1
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

29088:GPSM1
gene id: 29088:GPSM1
uniprot id: A0A2Y9H4T2
uniprot id: A0A2Y9H4U3
uniprot id: A0A2Y9H4U8
uniprot id: A0A8M1MYE4
names: Similarity
messages: Belongs to the GPSM family.

29088:CTSA
gene id: 29088:CTSA
uniprot id: A0A2Y9GZC4
uniprot id: A0A8M1MP95
names: Similarity
messages: Belongs to the peptidase S10 family.

29088:NCBP3
gene id: 29088:NCBP3
uniprot id: A0A2Y9IEJ3
names: Similarity
messages: Belongs to the NCBP3 family.

29088:TNRC6C
gene id: 29088:TNRC6C
uniprot id: A0A8M1MU04
names: Similarity
messages: Belongs to the GW182 family.

29088:NPLOC4
gene id: 29088:NPLOC4
uniprot id: A0A2Y9GBH0
names: Similarity
messages: Belongs to the NPL4 family.

29088:DCLK2
gene id: 29088:DCLK2
uniprot id: A0A2Y9HXF7
uniprot id: A0A2Y9HZ01
uniprot id: A0A8M1M450
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

29088:IL12A
gene id: 29088:IL12A
uniprot id: A0A2Y9I7V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-6 superfamily.
messages: Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Heterodimerizes with IL12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine. IL-12 is primarily produced by professional antigen-presenting cells (APCs) such as B-cells and dendritic cells (DCs) as well as macrophages and granulocytes and regulates T-cell and natural killer-cell responses, induces the production of interferon-gamma (IFN-gamma), favors the differentiation of T-helper 1 (Th1) cells and is an important link between innate resistance and adaptive immunity. Mechanistically, exerts its biological effects through a receptor composed of IL12R1 and IL12R2 subunits. Binding to the receptor results in the rapid tyrosine phosphorylation of a number of cellular substrates including the JAK family kinases TYK2 and JAK2. In turn, recruited STAT4 gets phosphorylated and translocates to the nucleus where it regulates cytokine/growth factor responsive genes. As part of IL-35, plays essential roles in maintaining the immune homeostasis of the liver microenvironment and functions also as an immune-suppressive cytokine. Mediates biological events through unconventional receptors composed of IL12RB2 and gp130/IL6ST heterodimers or homodimers. Signaling requires the transcription factors STAT1 and STAT4, which form a unique heterodimer that binds to distinct DNA sites.
messages: Secreted

29088:LOC110575283
gene id: 29088:LOC110575283
uniprot id: A0A8M1MD07
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

29088:GRPR
gene id: 29088:GRPR
uniprot id: A0A2Y9GEM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:SCG3
gene id: 29088:SCG3
uniprot id: A0A2Y9HCU5
names: Subcellular Location Annotation
messages: Membrane
messages: Secreted
messages: secretory vesicle membrane

29088:LOC110582755
gene id: 29088:LOC110582755
uniprot id: A0A2Y9H9P0
names: Similarity
names: Subunit
messages: Belongs to the PIP family.
messages: Monomer. Interacts with AZGP1.

29088:MTIF2
gene id: 29088:MTIF2
uniprot id: A0A8M1MNC0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

29088:B3GNT9
gene id: 29088:B3GNT9
uniprot id: A0A2Y9IG68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:CFAP36
gene id: 29088:CFAP36
uniprot id: A0A2Y9HYS9
names: Similarity
messages: Belongs to the CFAP36 family.

29088:TFAP2E
gene id: 29088:TFAP2E
uniprot id: A0A8M1MG14
names: Similarity
messages: Belongs to the AP-2 family.

29088:LOC110589767
gene id: 29088:LOC110589767
uniprot id: A0A2Y9I383
uniprot id: A0A8M1MB17
names: Function
names: Similarity
messages: Belongs to the TYW1 family.
messages: Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis.

29088:DMRT3
gene id: 29088:DMRT3
uniprot id: A0A8M1MS43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

29088:GPKOW
gene id: 29088:GPKOW
uniprot id: A0A8M1M5C1
uniprot id: A0A8M1M935
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOS2 family.
messages: Nucleus
messages: RNA-binding protein involved in pre-mRNA splicing.

29088:CIAO2A
gene id: 29088:CIAO2A
uniprot id: A0A2Y9HD25
names: Similarity
messages: Belongs to the MIP18 family.

29088:FAM98C
gene id: 29088:FAM98C
uniprot id: A0A2Y9HXP7
names: Similarity
messages: Belongs to the FAM98 family.

29088:TNFAIP3
gene id: 29088:TNFAIP3
uniprot id: A0A2Y9HAQ7
uniprot id: A0A2Y9HB21
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:CACNB3
gene id: 29088:CACNB3
uniprot id: A0A2Y9IA42
uniprot id: A0A2Y9IGP9
uniprot id: A0A8M1MA98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Cytoplasm

29088:SFXN4
gene id: 29088:SFXN4
uniprot id: A0A2Y9HTR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane

29088:ISYNA1
gene id: 29088:ISYNA1
uniprot id: A0A2Y9GIF2
uniprot id: A0A2Y9GNN0
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

29088:MRPS33
gene id: 29088:MRPS33
uniprot id: A0A2Y9HG13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

29088:LOC110571320
gene id: 29088:LOC110571320
uniprot id: A0A8M1M5A2
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

29088:JAG1
gene id: 29088:JAG1
uniprot id: A0A2Y9GZW5
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

29088:ARID3B
gene id: 29088:ARID3B
uniprot id: A0A8M1MJN4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Nucleus
messages: Transcription factor.

29088:ASIC1
gene id: 29088:ASIC1
uniprot id: A0A2Y9I9B5
names: Subcellular Location Annotation
messages: Membrane

29088:CTNNA2
gene id: 29088:CTNNA2
uniprot id: A0A8M1MMH4
uniprot id: A0A8M1MMH5
uniprot id: A0A8M1MPG4
uniprot id: A0A8M1MQS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction

29088:UNC50
gene id: 29088:UNC50
uniprot id: A0A2Y9HYZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane
messages: Nucleus inner membrane

29088:IRX1
gene id: 29088:IRX1
uniprot id: A0A2Y9GU12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

29088:LOC110585519
gene id: 29088:LOC110585519
uniprot id: A0A2Y9HPI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:CHAT
gene id: 29088:CHAT
uniprot id: A0A2Y9I0D3
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

29088:POLR2G
gene id: 29088:POLR2G
uniprot id: A0A2Y9GS15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. RPB4 and RPB7 form a subcomplex that protrudes from the 10-subunit Pol II core complex.
messages: DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

29088:ACTRT3
gene id: 29088:ACTRT3
uniprot id: A0A2Y9I393
names: Similarity
messages: Belongs to the actin family.

29088:CCR6
gene id: 29088:CCR6
uniprot id: A0A2Y9HII4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:ITPRIPL2
gene id: 29088:ITPRIPL2
uniprot id: A0A2Y9HX18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

29088:LOC110573438
gene id: 29088:LOC110573438
uniprot id: A0A2Y9GJH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:TXNRD2
gene id: 29088:TXNRD2
uniprot id: A0A8M1MWS4
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

29088:PGAM1
gene id: 29088:PGAM1
uniprot id: A0A2Y9I132
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

29088:LOC110581192
gene id: 29088:LOC110581192
uniprot id: A0A2Y9HA45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:PAX1
gene id: 29088:PAX1
uniprot id: A0A2Y9HXX1
names: Subcellular Location Annotation
messages: Nucleus

29088:LTB
gene id: 29088:LTB
uniprot id: A0A2Y9HLN2
names: Similarity
messages: Belongs to the tumor necrosis factor family.

29088:RRAGB
gene id: 29088:RRAGB
uniprot id: A0A2Y9HZM8
uniprot id: A0A2Y9I3S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

29088:JPT2
gene id: 29088:JPT2
uniprot id: A0A2Y9HQC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

29088:GBA2
gene id: 29088:GBA2
uniprot id: A0A2Y9HB71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the non-lysosomal glucosylceramidase family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.

29088:PRR5
gene id: 29088:PRR5
uniprot id: A0A2Y9H762
names: Similarity
messages: Belongs to the PROTOR family.

29088:LOC110576215
gene id: 29088:LOC110576215
uniprot id: A0A8M1MNP8
names: Similarity
messages: Belongs to the actin family.

29088:DYNC2LI1
gene id: 29088:DYNC2LI1
uniprot id: A0A2Y9I3Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light intermediate chain family.
messages: centrosome
messages: cilium
messages: cilium axoneme
messages: cilium basal body

29088:SLC5A3
gene id: 29088:SLC5A3
uniprot id: A0A2Y9G673
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

29088:LMNA
gene id: 29088:LMNA
uniprot id: A0A8M1MD68
uniprot id: A0A8M1MDB8
uniprot id: A0A8M1MGT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: Nucleus lamina

29088:RABEP1
gene id: 29088:RABEP1
uniprot id: A0A2Y9HES8
uniprot id: A0A2Y9HEU0
uniprot id: A0A2Y9HF62
uniprot id: A0A2Y9HL37
uniprot id: A0A2Y9HL42
uniprot id: A0A2Y9HL83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rabaptin family.
messages: Cytoplasm
messages: Early endosome
messages: Endosome

29088:ODAD4
gene id: 29088:ODAD4
uniprot id: A0A2Y9GIS9
names: Subcellular Location Annotation
messages: cilium axoneme

29088:ST14
gene id: 29088:ST14
uniprot id: A0A2Y9HRE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S1 family.
messages: Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site.
messages: Interacts with CDCP1. May interact with TMEFF1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:AMHR2
gene id: 29088:AMHR2
uniprot id: A0A2Y9GT15
uniprot id: A0A2Y9GTA6
uniprot id: A0A8M1MCI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane
messages: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.

29088:LOC110594163
gene id: 29088:LOC110594163
uniprot id: A0A8M1MVV7
names: Similarity
messages: Belongs to the RPGRIP1 family.

29088:GRIK3
gene id: 29088:GRIK3
uniprot id: A0A8M1MB54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Membrane

29088:RRAGA
gene id: 29088:RRAGA
uniprot id: A0A2Y9GL14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

29088:CPNE1
gene id: 29088:CPNE1
uniprot id: A0A2Y9GZD2
uniprot id: A0A2Y9H5X3
names: Similarity
messages: Belongs to the copine family.

29088:MYO1H
gene id: 29088:MYO1H
uniprot id: A0A2Y9IA67
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

29088:PRDM14
gene id: 29088:PRDM14
uniprot id: A0A2Y9GYB1
names: Subcellular Location Annotation
messages: Nucleus

29088:DCN
gene id: 29088:DCN
uniprot id: A0A2Y9GYX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: Binds to type I and type II collagen, fibronectin and TGF-beta. Forms a ternary complex with MFAP2 and ELN.
messages: May affect the rate of fibrils formation.
messages: extracellular matrix

29088:EIF5
gene id: 29088:EIF5
uniprot id: A0A2Y9G979
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

29088:PIAS2
gene id: 29088:PIAS2
uniprot id: A0A8M1MTM8
uniprot id: A0A8M1MVF9
names: Similarity
messages: Belongs to the PIAS family.

29088:KRT1
gene id: 29088:KRT1
uniprot id: A0A2Y9GT18
uniprot id: A0A8M1MBV8
uniprot id: A0A8M1MC06
uniprot id: A0A8M1ME40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

29088:MINDY3
gene id: 29088:MINDY3
uniprot id: A0A2Y9HKT3
uniprot id: A0A2Y9HL07
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

29088:MMP28
gene id: 29088:MMP28
uniprot id: A0A2Y9I7Q9
uniprot id: A0A2Y9IC66
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

29088:TGS1
gene id: 29088:TGS1
uniprot id: A0A8M1M8N7
uniprot id: A0A8M1MC71
names: Similarity
messages: Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.

29088:SEZ6
gene id: 29088:SEZ6
uniprot id: A0A2Y9I805
uniprot id: A0A2Y9IEM3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:CEP170
gene id: 29088:CEP170
uniprot id: A0A2Y9GGY2
names: Similarity
messages: Belongs to the CEP170 family.

29088:BDH1
gene id: 29088:BDH1
uniprot id: A0A2Y9HFG5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29088:C13H9orf64
gene id: 29088:C13H9orf64
uniprot id: A0A2Y9G606
names: Function
names: Similarity
messages: Belongs to the QNG1 protein family.
messages: Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly.

29088:LOC110571920
gene id: 29088:LOC110571920
uniprot id: A0A2Y9G9Y1
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

29088:CHMP4C
gene id: 29088:CHMP4C
uniprot id: A0A2Y9H1F3
uniprot id: A0A8M1M8R7
names: Similarity
messages: Belongs to the SNF7 family.

29088:MAP7D2
gene id: 29088:MAP7D2
uniprot id: A0A8M1M1A0
uniprot id: A0A8M1M1L2
uniprot id: A0A8M1M5C6
names: Similarity
messages: Belongs to the MAP7 family.

29088:SKOR2
gene id: 29088:SKOR2
uniprot id: A0A2Y9GXK3
names: Similarity
messages: Belongs to the SKI family.

29088:CLCA4
gene id: 29088:CLCA4
uniprot id: A0A2Y9H308
names: Similarity
messages: Belongs to the CLCR family.

29088:ABCA12
gene id: 29088:ABCA12
uniprot id: A0A8M1MFC1
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110574752
gene id: 29088:LOC110574752
uniprot id: A0A2Y9GJG3
names: Similarity
messages: Belongs to the centrin family.

29088:STK39
gene id: 29088:STK39
uniprot id: A0A2Y9I864
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

29088:POP5
gene id: 29088:POP5
uniprot id: A0A2Y9ICS9
uniprot id: A0A8M1MYV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

29088:LOC110577862
gene id: 29088:LOC110577862
uniprot id: A0A2Y9GUK8
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:PROK2
gene id: 29088:PROK2
uniprot id: A0A2Y9HMI9
uniprot id: A0A2Y9HMR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

29088:LOC110570070
gene id: 29088:LOC110570070
uniprot id: A0A2Y9HKK2
names: Similarity
messages: Belongs to the GroES chaperonin family.

29088:MEMO1
gene id: 29088:MEMO1
uniprot id: A0A2Y9HUH1
uniprot id: A0A8M1MMI0
uniprot id: A0A8M1MQT0
uniprot id: A0A8M1MWQ5
names: Similarity
messages: Belongs to the MEMO1 family.

29088:LOC110580098
gene id: 29088:LOC110580098
uniprot id: A0A8M1MTN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

29088:RHOT2
gene id: 29088:RHOT2
uniprot id: A0A2Y9HPH9
uniprot id: A0A2Y9HPY0
uniprot id: A0A8M1MAT0
uniprot id: A0A8M1MB10
uniprot id: A0A8M1MD41
uniprot id: A0A8M1MEH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

29088:ITM2C
gene id: 29088:ITM2C
uniprot id: A0A2Y9H313
uniprot id: A0A2Y9H9P1
uniprot id: A0A8M1M687
uniprot id: A0A8M1M8N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

29088:RPRD1A
gene id: 29088:RPRD1A
uniprot id: A0A2Y9GRF5
uniprot id: A0A8M1MYV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the RNA polymerase II complex.
messages: Belongs to the UPF0400 (RTT103) family.
messages: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.
messages: Nucleus

29088:LOC110580257
gene id: 29088:LOC110580257
uniprot id: A0A2Y9H6W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:GASK1B
gene id: 29088:GASK1B
uniprot id: A0A2Y9HYX0
names: Similarity
messages: Belongs to the GASK family.

29088:RNF141
gene id: 29088:RNF141
uniprot id: A0A2Y9GQ75
names: Function
messages: May be involved in spermatogenesis.

29088:LOC110576146
gene id: 29088:LOC110576146
uniprot id: A0A2Y9GNQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:TCL1B
gene id: 29088:TCL1B
uniprot id: A0A2Y9GD27
names: Similarity
messages: Belongs to the TCL1 family.

29088:ZDHHC1
gene id: 29088:ZDHHC1
uniprot id: A0A2Y9IBQ9
uniprot id: A0A2Y9IBR4
uniprot id: A0A2Y9IBW1
uniprot id: A0A2Y9ICJ9
uniprot id: A0A2Y9ICK6
uniprot id: A0A2Y9IG63
uniprot id: A0A2Y9IJA0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

29088:LOC110581348
gene id: 29088:LOC110581348
uniprot id: A0A8M1MSV2
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110592480
gene id: 29088:LOC110592480
uniprot id: A0A2Y9ICQ4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

29088:EZR
gene id: 29088:EZR
uniprot id: A0A2Y9HC45
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton
messages: microvillus

29088:METTL3
gene id: 29088:METTL3
uniprot id: A0A2Y9HP91
names: Similarity
messages: Belongs to the MT-A70-like family.

29088:NOP58
gene id: 29088:NOP58
uniprot id: A0A2Y9I518
uniprot id: A0A2Y9I568
uniprot id: A0A8M1M8G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

29088:CHRNA2
gene id: 29088:CHRNA2
uniprot id: A0A2Y9HXG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:LOC110579713
gene id: 29088:LOC110579713
uniprot id: A0A8M1MYG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA3 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Membrane
messages: Mitochondrion inner membrane

29088:IFI6
gene id: 29088:IFI6
uniprot id: A0A2Y9GJD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane

29088:CNDP2
gene id: 29088:CNDP2
uniprot id: A0A2Y9GS32
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

29088:FRZB
gene id: 29088:FRZB
uniprot id: A0A2Y9I513
names: Caution
names: Function
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.

29088:CA6
gene id: 29088:CA6
uniprot id: A0A2Y9GIU3
uniprot id: A0A2Y9GIU6
uniprot id: A0A8M1M9V9
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

29088:LOC110590260
gene id: 29088:LOC110590260
uniprot id: A0A2Y9HYQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

29088:CASP3
gene id: 29088:CASP3
uniprot id: A0A2Y9HDH4
uniprot id: A0A2Y9HDV2
names: Similarity
messages: Belongs to the peptidase C14A family.

29088:ARPIN
gene id: 29088:ARPIN
uniprot id: A0A2Y9GBH8
uniprot id: A0A2Y9GBJ9
uniprot id: A0A2Y9GE65
names: Similarity
messages: Belongs to the Arpin family.

29088:PIK3C2G
gene id: 29088:PIK3C2G
uniprot id: A0A2Y9H372
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

29088:LOC110575508
gene id: 29088:LOC110575508
uniprot id: A0A8M1M9E3
names: Function
names: Similarity
messages: Belongs to the RNase H family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

29088:SPSB3
gene id: 29088:SPSB3
uniprot id: A0A2Y9HPT9
uniprot id: A0A2Y9HV32
names: Function
names: Similarity
messages: Belongs to the SPSB family.
messages: May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

29088:ESF1
gene id: 29088:ESF1
uniprot id: A0A2Y9HXD4
uniprot id: A0A2Y9I2E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF1 family.
messages: nucleolus

29088:CERS5
gene id: 29088:CERS5
uniprot id: A0A2Y9I946
uniprot id: A0A8M1MDY5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

29088:KCNQ3
gene id: 29088:KCNQ3
uniprot id: A0A2Y9H2B1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:CLK2
gene id: 29088:CLK2
uniprot id: A0A2Y9GEU8
uniprot id: A0A2Y9GI55
uniprot id: A0A8M1MEB3
uniprot id: A0A8M1MGG5
uniprot id: A0A8M1MN21
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:GPR137C
gene id: 29088:GPR137C
uniprot id: A0A2Y9I4N0
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

29088:GJD4
gene id: 29088:GJD4
uniprot id: A0A2Y9GQY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

29088:ITFG1
gene id: 29088:ITFG1
uniprot id: A0A2Y9IC49
names: Similarity
messages: Belongs to the TIP family.

29088:LOC110574962
gene id: 29088:LOC110574962
uniprot id: A0A2Y9GNH8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:OSBPL7
gene id: 29088:OSBPL7
uniprot id: A0A8M1MUD2
names: Similarity
messages: Belongs to the OSBP family.

29088:LOC110589741
gene id: 29088:LOC110589741
uniprot id: A0A8M1MCW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

29088:CENPM
gene id: 29088:CENPM
uniprot id: A0A2Y9GVS6
uniprot id: A0A2Y9GW02
uniprot id: A0A2Y9GW46
uniprot id: A0A2Y9H052
uniprot id: A0A2Y9H1Z6
names: Subcellular Location Annotation
messages: Nucleus

29088:CLDN23
gene id: 29088:CLDN23
uniprot id: A0A2Y9HKA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

29088:ADRB3
gene id: 29088:ADRB3
uniprot id: A0A2Y9GDR8
uniprot id: A0A2Y9GDU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
messages: Cell membrane
messages: Interacts with ARRDC3.
messages: Membrane

29088:ZC3HC1
gene id: 29088:ZC3HC1
uniprot id: A0A2Y9HTU7
uniprot id: A0A8M1MTA3
names: Subcellular Location Annotation
messages: Nucleus

29088:SEPTIN14
gene id: 29088:SEPTIN14
uniprot id: A0A2Y9I3I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

29088:HMGN3
gene id: 29088:HMGN3
uniprot id: A0A2Y9HB08
uniprot id: A0A2Y9HBA3
uniprot id: A0A2Y9HH46
uniprot id: A0A2Y9HHS4
uniprot id: A0A8M1MHI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

29088:LOC123325301
gene id: 29088:LOC123325301
uniprot id: A0A8M1MK05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:MYH9
gene id: 29088:MYH9
uniprot id: A0A2Y9GV38
uniprot id: A0A8M1MDY0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

29088:RPL13
gene id: 29088:RPL13
uniprot id: A0A2Y9I210
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

29088:MASP2
gene id: 29088:MASP2
uniprot id: A0A2Y9GKT3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110586900
gene id: 29088:LOC110586900
uniprot id: A0A2Y9HU37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

29088:LOC110591967
gene id: 29088:LOC110591967
uniprot id: A0A8M1M8A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:TM7SF3
gene id: 29088:TM7SF3
uniprot id: A0A2Y9H3Q6
names: Subcellular Location Annotation
messages: Membrane

29088:MRPL11
gene id: 29088:MRPL11
uniprot id: A0A2Y9GNG0
uniprot id: A0A2Y9GSF6
uniprot id: A0A8M1MXI6
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

29088:PPFIA4
gene id: 29088:PPFIA4
uniprot id: A0A8M1MEH7
uniprot id: A0A8M1MEI2
uniprot id: A0A8M1MEL5
uniprot id: A0A8M1MEM0
uniprot id: A0A8M1MGN0
uniprot id: A0A8M1MGN6
uniprot id: A0A8M1MI19
uniprot id: A0A8M1MI24
uniprot id: A0A8M1MN89
uniprot id: A0A8M1MN94
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

29088:ATG16L2
gene id: 29088:ATG16L2
uniprot id: A0A2Y9I9B7
uniprot id: A0A2Y9ID84
uniprot id: A0A2Y9IG10
names: Similarity
messages: Belongs to the WD repeat ATG16 family.

29088:GABRA3
gene id: 29088:GABRA3
uniprot id: A0A2Y9GJ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:CDKL4
gene id: 29088:CDKL4
uniprot id: A0A2Y9HNM2
uniprot id: A0A2Y9HV99
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:PSMB3
gene id: 29088:PSMB3
uniprot id: A0A2Y9ICV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

29088:MFSD4A
gene id: 29088:MFSD4A
uniprot id: A0A8M1MDQ5
names: Subcellular Location Annotation
messages: Membrane

29088:ITGAX
gene id: 29088:ITGAX
uniprot id: A0A2Y9I360
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

29088:AASS
gene id: 29088:AASS
uniprot id: A0A2Y9HYP7
names: Similarity
messages: In the C-terminal section; belongs to the saccharopine dehydrogenase family.
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

29088:HNF4A
gene id: 29088:HNF4A
uniprot id: A0A2Y9GZH8
uniprot id: A0A2Y9GZN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

29088:SCNM1
gene id: 29088:SCNM1
uniprot id: A0A2Y9GWJ6
names: Subcellular Location Annotation
messages: Nucleus speckle
messages: nucleoplasm

29088:LOC110572783
gene id: 29088:LOC110572783
uniprot id: A0A2Y9GHA9
names: Similarity
names: Subunit
messages: Belongs to the TRAPPC13 family.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.

29088:ENTPD1
gene id: 29088:ENTPD1
uniprot id: A0A2Y9HZZ8
uniprot id: A0A2Y9I1K2
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

29088:LOC110591787
gene id: 29088:LOC110591787
uniprot id: A0A2Y9I331
uniprot id: A0A2Y9I3D0
uniprot id: A0A2Y9I3M6
uniprot id: A0A2Y9IA41
uniprot id: A0A8M1M689
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

29088:FASN
gene id: 29088:FASN
uniprot id: A0A2Y9GC56
names: Function
messages: Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain.

29088:ANAPC16
gene id: 29088:ANAPC16
uniprot id: A0A2Y9HU78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC16 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: Cytoplasm
messages: Nucleus
messages: kinetochore

29088:LOC110589688
gene id: 29088:LOC110589688
uniprot id: A0A2Y9HWK2
uniprot id: A0A2Y9I2W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCMBP family.
messages: Nucleus

29088:HDDC2
gene id: 29088:HDDC2
uniprot id: A0A2Y9HAP4
uniprot id: A0A2Y9HGS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

29088:VPS13C
gene id: 29088:VPS13C
uniprot id: A0A8M1MN07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS13 family.
messages: Lipid droplet

29088:PPP3R2
gene id: 29088:PPP3R2
uniprot id: A0A2Y9H5Y2
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

29088:EFS
gene id: 29088:EFS
uniprot id: A0A2Y9HHK2
uniprot id: A0A2Y9HHZ8
names: Similarity
messages: Belongs to the CAS family.

29088:ATG4D
gene id: 29088:ATG4D
uniprot id: A0A2Y9IEA7
uniprot id: A0A8M1MAZ3
uniprot id: A0A8M1MB29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

29088:ADAMTS16
gene id: 29088:ADAMTS16
uniprot id: A0A2Y9I2M5
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:RRP12
gene id: 29088:RRP12
uniprot id: A0A2Y9I184
uniprot id: A0A8M1MFA2
uniprot id: A0A8M1MIQ0
names: Similarity
messages: Belongs to the RRP12 family.

29088:APH1B
gene id: 29088:APH1B
uniprot id: A0A2Y9HCZ1
uniprot id: A0A2Y9HDC0
uniprot id: A0A2Y9HJ63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

29088:HACD1
gene id: 29088:HACD1
uniprot id: A0A8M1MDN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:POMT1
gene id: 29088:POMT1
uniprot id: A0A2Y9HCK0
uniprot id: A0A2Y9HDT5
uniprot id: A0A8M1MRZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

29088:LOC123324062
gene id: 29088:LOC123324062
uniprot id: A0A8M1M8L2
names: Similarity
messages: Belongs to the PPDPF family.

29088:RPA4
gene id: 29088:RPA4
uniprot id: A0A2Y9HH75
names: Similarity
messages: Belongs to the replication factor A protein 2 family.

29088:DPH3
gene id: 29088:DPH3
uniprot id: A0A2Y9G6F0
uniprot id: A0A8M1MEX6
names: Similarity
messages: Belongs to the DPH3 family.

29088:COQ8A
gene id: 29088:COQ8A
uniprot id: A0A2Y9H8F7
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

29088:LOC110579002
gene id: 29088:LOC110579002
uniprot id: A0A8M1MPP1
names: Similarity
messages: Belongs to the CD200R family.

29088:MTIF3
gene id: 29088:MTIF3
uniprot id: A0A2Y9G4P6
names: Similarity
messages: Belongs to the IF-3 family.

29088:NLE1
gene id: 29088:NLE1
uniprot id: A0A2Y9IBV5
uniprot id: A0A8M1MUJ0
names: Subcellular Location Annotation
messages: nucleolus

29088:STK11
gene id: 29088:STK11
uniprot id: A0A2Y9IAX9
uniprot id: A0A2Y9IB14
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. LKB1 subfamily.

29088:LOC110576122
gene id: 29088:LOC110576122
uniprot id: A0A2Y9GNN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110576598
gene id: 29088:LOC110576598
uniprot id: A0A8M1MQ66
uniprot id: A0A8M1MX88
names: Similarity
messages: Belongs to the calcitonin family.

29088:PSMB6
gene id: 29088:PSMB6
uniprot id: A0A2Y9HF50
uniprot id: A0A8M1MXC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

29088:LOC110573129
gene id: 29088:LOC110573129
uniprot id: A0A8M1M4P0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer or homodimer.

29088:RBKS
gene id: 29088:RBKS
uniprot id: A0A2Y9HNP7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

29088:TLCD3A
gene id: 29088:TLCD3A
uniprot id: A0A2Y9I7B4
uniprot id: A0A8M1MUE1
names: Subcellular Location Annotation
messages: Membrane

29088:LITAF
gene id: 29088:LITAF
uniprot id: A0A2Y9HPR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

29088:ZNF174
gene id: 29088:ZNF174
uniprot id: A0A2Y9HQJ0
uniprot id: A0A8M1MCF1
names: Subcellular Location Annotation
messages: Nucleus

29088:BICD2
gene id: 29088:BICD2
uniprot id: A0A2Y9HK95
uniprot id: A0A2Y9HKH9
names: Similarity
messages: Belongs to the BicD family.

29088:CDK15
gene id: 29088:CDK15
uniprot id: A0A2Y9I4M8
uniprot id: A0A2Y9I9E7
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:CAMSAP2
gene id: 29088:CAMSAP2
uniprot id: A0A2Y9GGX2
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

29088:DNMT3L
gene id: 29088:DNMT3L
uniprot id: A0A2Y9G9N8
names: Subcellular Location Annotation
messages: Nucleus

29088:VPS53
gene id: 29088:VPS53
uniprot id: A0A2Y9IFC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

29088:CERS4
gene id: 29088:CERS4
uniprot id: A0A2Y9I9Z3
uniprot id: A0A8M1MM44
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

29088:PRDM15
gene id: 29088:PRDM15
uniprot id: A0A8M1ME72
names: Subcellular Location Annotation
messages: Nucleus

29088:KCNU1
gene id: 29088:KCNU1
uniprot id: A0A8M1M8B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa1.1/KCNMA1 sub-subfamily.
messages: Membrane

29088:GRIK4
gene id: 29088:GRIK4
uniprot id: A0A2Y9HK52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

29088:DEGS2
gene id: 29088:DEGS2
uniprot id: A0A2Y9GBP9
uniprot id: A0A2Y9GCP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:MAP1LC3A
gene id: 29088:MAP1LC3A
uniprot id: A0A2Y9GZK7
names: Similarity
messages: Belongs to the ATG8 family.

29088:ETV4
gene id: 29088:ETV4
uniprot id: A0A2Y9GE78
uniprot id: A0A2Y9GIM0
uniprot id: A0A8M1MU29
uniprot id: A0A8M1MVV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

29088:CHAC2
gene id: 29088:CHAC2
uniprot id: A0A8M1MW38
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

29088:OVCA2
gene id: 29088:OVCA2
uniprot id: A0A2Y9I6N2
names: Similarity
messages: Belongs to the LovG family.

29088:ACTR3
gene id: 29088:ACTR3
uniprot id: A0A2Y9HIX3
names: Similarity
messages: Belongs to the actin family.

29088:KCNE1
gene id: 29088:KCNE1
uniprot id: A0A2Y9G3M9
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the potassium channel KCNE family.
messages: Cell membrane
messages: Membrane

29088:PTCH2
gene id: 29088:PTCH2
uniprot id: A0A2Y9GK06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

29088:LOC110589223
gene id: 29088:LOC110589223
uniprot id: A0A2Y9HV11
uniprot id: A0A8M1MF24
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9.
messages: Membrane
messages: basement membrane

29088:LOC110591947
gene id: 29088:LOC110591947
uniprot id: A0A2Y9I405
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

29088:LOC110581669
gene id: 29088:LOC110581669
uniprot id: A0A2Y9H6K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:FOXP4
gene id: 29088:FOXP4
uniprot id: A0A8M1MIF5
uniprot id: A0A8M1MIF7
names: Subcellular Location Annotation
messages: Nucleus

29088:CD36
gene id: 29088:CD36
uniprot id: A0A2Y9H0W2
names: Similarity
messages: Belongs to the CD36 family.

29088:LOC110577481
gene id: 29088:LOC110577481
uniprot id: A0A2Y9GTE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:NHSL2
gene id: 29088:NHSL2
uniprot id: A0A8M1M9C6
names: Similarity
messages: Belongs to the NHS family.

29088:GALNT8
gene id: 29088:GALNT8
uniprot id: A0A2Y9H9X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

29088:CPEB3
gene id: 29088:CPEB3
uniprot id: A0A2Y9HV79
uniprot id: A0A2Y9HV83
uniprot id: A0A8M1MIN2
names: Similarity
messages: Belongs to the RRM CPEB family.

29088:HIGD1A
gene id: 29088:HIGD1A
uniprot id: A0A2Y9G6F6
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

29088:LOC110587395
gene id: 29088:LOC110587395
uniprot id: A0A8M1MLT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.

29088:RNF175
gene id: 29088:RNF175
uniprot id: A0A2Y9HS31
names: Subcellular Location Annotation
messages: Membrane

29088:B3GNT7
gene id: 29088:B3GNT7
uniprot id: A0A2Y9H331
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:LOC110575131
gene id: 29088:LOC110575131
uniprot id: A0A2Y9GQW8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:LIN9
gene id: 29088:LIN9
uniprot id: A0A2Y9G7X8
uniprot id: A0A8M1MEU2
uniprot id: A0A8M1MEX7
names: Similarity
messages: Belongs to the lin-9 family.

29088:LOC110584476
gene id: 29088:LOC110584476
uniprot id: A0A8M1MXL7
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:DEFB116
gene id: 29088:DEFB116
uniprot id: A0A2Y9H079
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

29088:LOC110581272
gene id: 29088:LOC110581272
uniprot id: A0A8M1MT49
names: Similarity
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Monomer.

29088:CACNA1C
gene id: 29088:CACNA1C
uniprot id: A0A2Y9H429
uniprot id: A0A2Y9H435
uniprot id: A0A2Y9H436
uniprot id: A0A2Y9H440
uniprot id: A0A2Y9H457
uniprot id: A0A2Y9H462
uniprot id: A0A2Y9H9C3
uniprot id: A0A2Y9H9D0
uniprot id: A0A2Y9H9D8
uniprot id: A0A2Y9HAR9
uniprot id: A0A2Y9HAS5
uniprot id: A0A2Y9HAT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1C subfamily.
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic density membrane
messages: T-tubule
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.
messages: dendrite
messages: sarcolemma

29088:GINS1
gene id: 29088:GINS1
uniprot id: A0A2Y9HXI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Chromosome
messages: Component of the GINS complex which is a heterotetramer of GINS1, GINS2, GINS3 and GINS4. Forms a stable subcomplex with GINS4. GINS complex interacts with DNA primase in vitro. Component of the CMG helicase complex, a hexameric ring of related MCM2-7 subunits stabilized by CDC45 and the tetrameric GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.

29088:LOC110581127
gene id: 29088:LOC110581127
uniprot id: A0A2Y9H4I6
uniprot id: A0A2Y9H4J5
uniprot id: A0A2Y9H9W8
uniprot id: A0A2Y9HB76
uniprot id: A0A8M1MYX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

29088:PDE4B
gene id: 29088:PDE4B
uniprot id: A0A2Y9G9M3
uniprot id: A0A2Y9GC76
uniprot id: A0A2Y9GDC0
uniprot id: A0A8M1M9C1
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

29088:SLC7A3
gene id: 29088:SLC7A3
uniprot id: A0A2Y9GAS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

29088:LOC110586434
gene id: 29088:LOC110586434
uniprot id: A0A2Y9HKP6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ARHGAP26
gene id: 29088:ARHGAP26
uniprot id: A0A2Y9I279
uniprot id: A0A2Y9I8P9
names: Subcellular Location Annotation
messages: cytoskeleton
messages: focal adhesion

29088:HSD3B7
gene id: 29088:HSD3B7
uniprot id: A0A2Y9HXA1
uniprot id: A0A2Y9I3N7
names: Similarity
messages: Belongs to the 3-beta-HSD family.

29088:LOC110592684
gene id: 29088:LOC110592684
uniprot id: A0A8M1MSE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:ROCK1
gene id: 29088:ROCK1
uniprot id: A0A8M1MYY0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by RHOA binding. Inhibited by Y-27632.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Homodimer.
messages: Membrane
messages: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.

29088:MST1
gene id: 29088:MST1
uniprot id: A0A2Y9GTJ0
names: Caution
names: Similarity
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:RPRD1B
gene id: 29088:RPRD1B
uniprot id: A0A2Y9GZD6
uniprot id: A0A2Y9H3Z7
uniprot id: A0A8M1ML48
names: Function
names: Similarity
names: Subunit
messages: Associates with the RNA polymerase II complex.
messages: Belongs to the UPF0400 (RTT103) family.
messages: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD.

29088:IER5
gene id: 29088:IER5
uniprot id: A0A2Y9GGG7
names: Similarity
messages: Belongs to the IER family.

29088:PPEF1
gene id: 29088:PPEF1
uniprot id: A0A2Y9GNR9
names: Similarity
messages: Belongs to the PPP phosphatase family.

29088:SDC3
gene id: 29088:SDC3
uniprot id: A0A2Y9GLI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

29088:MTFR1L
gene id: 29088:MTFR1L
uniprot id: A0A8M1M7T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

29088:BUD13
gene id: 29088:BUD13
uniprot id: A0A2Y9HK44
uniprot id: A0A2Y9HK59
uniprot id: A0A8M1MQ42
uniprot id: A0A8M1MX70
names: Similarity
messages: Belongs to the CWC26 family.

29088:NOX3
gene id: 29088:NOX3
uniprot id: A0A2Y9HC24
names: Subcellular Location Annotation
messages: Membrane

29088:HAPLN1
gene id: 29088:HAPLN1
uniprot id: A0A2Y9HUJ8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:TBK1
gene id: 29088:TBK1
uniprot id: A0A2Y9G5J8
uniprot id: A0A8M1MA90
names: Subcellular Location Annotation
messages: Cytoplasm

29088:NR1H3
gene id: 29088:NR1H3
uniprot id: A0A2Y9GMN7
uniprot id: A0A2Y9GRL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

29088:NIPAL3
gene id: 29088:NIPAL3
uniprot id: A0A2Y9GJ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

29088:MIF
gene id: 29088:MIF
uniprot id: A0A2Y9GWL6
names: Similarity
messages: Belongs to the MIF family.

29088:NPSR1
gene id: 29088:NPSR1
uniprot id: A0A2Y9I0F3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:OAF
gene id: 29088:OAF
uniprot id: A0A2Y9HKU1
names: Similarity
messages: Belongs to the OAF family.

29088:TRAPPC3L
gene id: 29088:TRAPPC3L
uniprot id: A0A2Y9HBE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

29088:LOC110571700
gene id: 29088:LOC110571700
uniprot id: A0A2Y9GCZ3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

29088:ARG1
gene id: 29088:ARG1
uniprot id: A0A2Y9HC35
uniprot id: A0A8M1MLN0
uniprot id: A0A8M1MS88
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

29088:LOC110591054
gene id: 29088:LOC110591054
uniprot id: A0A2Y9I1F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:IST1
gene id: 29088:IST1
uniprot id: A0A2Y9IBL9
uniprot id: A0A2Y9ICF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IST1 family.
messages: Cytoplasmic vesicle
messages: Nucleus envelope

29088:SBNO2
gene id: 29088:SBNO2
uniprot id: A0A2Y9IAK6
uniprot id: A0A2Y9IBA2
names: Similarity
messages: Belongs to the SBNO family.

29088:VHL
gene id: 29088:VHL
uniprot id: A0A2Y9HFW0
uniprot id: A0A8M1MH11
names: Similarity
messages: Belongs to the VHL family.

29088:RAB19
gene id: 29088:RAB19
uniprot id: A0A2Y9HAH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane

29088:P2RX7
gene id: 29088:P2RX7
uniprot id: A0A2Y9HWJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P2X receptor family.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

29088:BECN2
gene id: 29088:BECN2
uniprot id: A0A2Y9GHD9
names: Similarity
messages: Belongs to the beclin family.

29088:MYOZ3
gene id: 29088:MYOZ3
uniprot id: A0A2Y9HM11
names: Similarity
messages: Belongs to the myozenin family.

29088:BASP1
gene id: 29088:BASP1
uniprot id: A0A2Y9I2U3
names: Similarity
messages: Belongs to the BASP1 family.

29088:RAD54L2
gene id: 29088:RAD54L2
uniprot id: A0A2Y9HMU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

29088:CELF5
gene id: 29088:CELF5
uniprot id: A0A8M1MKY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

29088:GBX2
gene id: 29088:GBX2
uniprot id: A0A2Y9G6V9
uniprot id: A0A2Y9GA22
names: Subcellular Location Annotation
messages: Nucleus

29088:ABCC3
gene id: 29088:ABCC3
uniprot id: A0A2Y9IEA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

29088:FITM1
gene id: 29088:FITM1
uniprot id: A0A2Y9HHV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIT family. FIT1 subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays an important role in the formation of lipid droplets (LDs), which are storage organelles at the center of lipid and energy homeostasis. Directly binds to diacylglycerol (DAGs) and triacylglycerol.

29088:AP2S1
gene id: 29088:AP2S1
uniprot id: A0A2Y9GCW8
uniprot id: A0A8M1MZF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cell membrane
messages: coated pit

29088:SLC1A3
gene id: 29088:SLC1A3
uniprot id: A0A2Y9HJT9
uniprot id: A0A8M1MGC1
uniprot id: A0A8M1MGC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

29088:CRHR1
gene id: 29088:CRHR1
uniprot id: A0A2Y9G595
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.
messages: Membrane

29088:PAPPA
gene id: 29088:PAPPA
uniprot id: A0A8M1MR72
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:FAM120A
gene id: 29088:FAM120A
uniprot id: A0A8M1MS42
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

29088:SLC7A11
gene id: 29088:SLC7A11
uniprot id: A0A2Y9G7X0
uniprot id: A0A8M1M461
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Cell membrane
messages: Membrane

29088:EPB41
gene id: 29088:EPB41
uniprot id: A0A2Y9GKV0
uniprot id: A0A2Y9GKV3
uniprot id: A0A2Y9GKZ0
uniprot id: A0A2Y9GKZ8
uniprot id: A0A2Y9GL53
uniprot id: A0A2Y9GL58
uniprot id: A0A2Y9GPS1
uniprot id: A0A2Y9GPS5
uniprot id: A0A2Y9GR96
uniprot id: A0A2Y9GRA0
names: Subcellular Location Annotation
messages: Nucleus
messages: cell cortex
messages: cytoskeleton

29088:DNAAF4
gene id: 29088:DNAAF4
uniprot id: A0A2Y9HD46
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Dynein axonemal particle
messages: neuron projection

29088:P4HA2
gene id: 29088:P4HA2
uniprot id: A0A2Y9I0R2
uniprot id: A0A2Y9I0R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

29088:KRT74
gene id: 29088:KRT74
uniprot id: A0A2Y9GT34
names: Similarity
messages: Belongs to the intermediate filament family.

29088:FOXH1
gene id: 29088:FOXH1
uniprot id: A0A2Y9GY74
names: Subcellular Location Annotation
messages: Nucleus

29088:UBA2
gene id: 29088:UBA2
uniprot id: A0A2Y9I552
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer of SAE1 and UBA2/SAE2. The heterodimer corresponds to the two domains that are encoded on a single polypeptide chain in ubiquitin-activating enzyme E1. Interacts with UBE2I.
messages: Nucleus
messages: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

29088:STRIP1
gene id: 29088:STRIP1
uniprot id: A0A2Y9H2C4
uniprot id: A0A8M1M9P6
names: Similarity
messages: Belongs to the STRIP family.

29088:SIAH3
gene id: 29088:SIAH3
uniprot id: A0A2Y9HPF0
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

29088:PTGES3
gene id: 29088:PTGES3
uniprot id: A0A2Y9H0E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p23/wos2 family.
messages: Cytoplasm
messages: Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation.
messages: Forms a complex with HSP70, HSP90 and other chaperones.

29088:IDE
gene id: 29088:IDE
uniprot id: A0A2Y9HW55
uniprot id: A0A2Y9HW78
uniprot id: A0A2Y9I0X0
uniprot id: A0A8M1ME06
names: Similarity
messages: Belongs to the peptidase M16 family.

29088:LOC110570676
gene id: 29088:LOC110570676
uniprot id: A0A2Y9G9F2
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

29088:ABCG1
gene id: 29088:ABCG1
uniprot id: A0A2Y9G7G9
uniprot id: A0A2Y9G7P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

29088:LBR
gene id: 29088:LBR
uniprot id: A0A2Y9GAJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus inner membrane

29088:NTRK3
gene id: 29088:NTRK3
uniprot id: A0A2Y9GAZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

29088:ITGA11
gene id: 29088:ITGA11
uniprot id: A0A2Y9HIF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

29088:RPL23A
gene id: 29088:RPL23A
uniprot id: A0A2Y9HIH4
uniprot id: A0A8M1MV35
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

29088:TASOR
gene id: 29088:TASOR
uniprot id: A0A2Y9HG60
uniprot id: A0A2Y9HGL2
uniprot id: A0A2Y9HMI4
uniprot id: A0A2Y9HMQ6
uniprot id: A0A8M1MU20
uniprot id: A0A8M1MVU7
uniprot id: A0A8M1MWZ6
names: Similarity
messages: Belongs to the TASOR family.

29088:ANTXR1
gene id: 29088:ANTXR1
uniprot id: A0A2Y9HYJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

29088:LOC110583425
gene id: 29088:LOC110583425
uniprot id: A0A8M1MCJ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

29088:EDNRB
gene id: 29088:EDNRB
uniprot id: A0A2Y9HUI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:PTGS1
gene id: 29088:PTGS1
uniprot id: A0A2Y9H5B9
uniprot id: A0A2Y9HC16
uniprot id: A0A8M1MSZ6
names: Caution
names: Similarity
messages: Belongs to the prostaglandin G/H synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:RPL21
gene id: 29088:RPL21
uniprot id: A0A2Y9G782
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

29088:TRIM67
gene id: 29088:TRIM67
uniprot id: A0A2Y9HJN5
names: Subcellular Location Annotation
messages: cytoskeleton

29088:B3GALT6
gene id: 29088:B3GALT6
uniprot id: A0A8M1MB27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:CCBE1
gene id: 29088:CCBE1
uniprot id: A0A2Y9GS06
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:CKB
gene id: 29088:CKB
uniprot id: A0A2Y9G8R9
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

29088:CASS4
gene id: 29088:CASS4
uniprot id: A0A2Y9G6Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

29088:RPIA
gene id: 29088:RPIA
uniprot id: A0A2Y9HNE7
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

29088:VEPH1
gene id: 29088:VEPH1
uniprot id: A0A2Y9I7N8
uniprot id: A0A2Y9I9T6
names: Similarity
messages: Belongs to the MELT/VEPH family.

29088:ACTL7B
gene id: 29088:ACTL7B
uniprot id: A0A2Y9H6N5
names: Similarity
messages: Belongs to the actin family.

29088:GAL3ST4
gene id: 29088:GAL3ST4
uniprot id: A0A2Y9GCG8
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

29088:MYCL
gene id: 29088:MYCL
uniprot id: A0A2Y9GPX0
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

29088:LIG4
gene id: 29088:LIG4
uniprot id: A0A2Y9HIT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

29088:FAM221B
gene id: 29088:FAM221B
uniprot id: A0A2Y9HAL4
names: Similarity
messages: Belongs to the FAM221 family.

29088:BRINP1
gene id: 29088:BRINP1
uniprot id: A0A2Y9H6D6
names: Similarity
messages: Belongs to the BRINP family.

29088:LOC110588693
gene id: 29088:LOC110588693
uniprot id: A0A8M1MFW6
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

29088:CNTNAP5
gene id: 29088:CNTNAP5
uniprot id: A0A2Y9HIL7
uniprot id: A0A8M1M845
names: Caution
names: Similarity
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:CAVIN2
gene id: 29088:CAVIN2
uniprot id: A0A2Y9I900
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

29088:SCGN
gene id: 29088:SCGN
uniprot id: A0A2Y9HLY6
names: Subcellular Location Annotation
messages: secretory vesicle membrane

29088:LOC110583235
gene id: 29088:LOC110583235
uniprot id: A0A2Y9HBB6
names: Similarity
messages: Belongs to the AAA ATPase family.

29088:SBK3
gene id: 29088:SBK3
uniprot id: A0A2Y9GFW4
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:DYRK2
gene id: 29088:DYRK2
uniprot id: A0A2Y9G5P6
uniprot id: A0A2Y9G643
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

29088:ADD3
gene id: 29088:ADD3
uniprot id: A0A2Y9HVU2
uniprot id: A0A2Y9HVU7
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

29088:LOC110580537
gene id: 29088:LOC110580537
uniprot id: A0A8M1MBV9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

29088:CAV3
gene id: 29088:CAV3
uniprot id: A0A2Y9HMC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

29088:STX1B
gene id: 29088:STX1B
uniprot id: A0A2Y9HXE7
names: Similarity
messages: Belongs to the syntaxin family.

29088:ZHX1
gene id: 29088:ZHX1
uniprot id: A0A2Y9GYX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

29088:LOC123323599
gene id: 29088:LOC123323599
uniprot id: A0A8M1M7B6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:APTX
gene id: 29088:APTX
uniprot id: A0A2Y9H5R8
uniprot id: A0A2Y9HCG6
names: Subcellular Location Annotation
messages: nucleolus
messages: nucleoplasm

29088:AP1G2
gene id: 29088:AP1G2
uniprot id: A0A2Y9HH48
uniprot id: A0A2Y9HNA9
uniprot id: A0A2Y9HNP4
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

29088:MAPK3
gene id: 29088:MAPK3
uniprot id: A0A2Y9HX44
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
messages: caveola
messages: focal adhesion

29088:LOC123323424
gene id: 29088:LOC123323424
uniprot id: A0A8M1M5Y0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC123324562
gene id: 29088:LOC123324562
uniprot id: A0A8M1MAL9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:DUS3L
gene id: 29088:DUS3L
uniprot id: A0A2Y9IHR2
uniprot id: A0A8M1MKN4
uniprot id: A0A8M1MP01
names: Similarity
messages: Belongs to the dus family. Dus3 subfamily.

29088:OIP5
gene id: 29088:OIP5
uniprot id: A0A2Y9HHU0
uniprot id: A0A8M1MJU8
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

29088:GLUD1
gene id: 29088:GLUD1
uniprot id: A0A2Y9I2T7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

29088:FAM199X
gene id: 29088:FAM199X
uniprot id: A0A2Y9G6D4
names: Similarity
messages: Belongs to the FAM199 family.

29088:YME1L1
gene id: 29088:YME1L1
uniprot id: A0A2Y9GU91
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

29088:LOC123324335
gene id: 29088:LOC123324335
uniprot id: A0A8M1M717
names: Function
names: Subunit
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

29088:PDPR
gene id: 29088:PDPR
uniprot id: A0A2Y9ICF2
names: Similarity
messages: Belongs to the GcvT family.

29088:TUBGCP5
gene id: 29088:TUBGCP5
uniprot id: A0A2Y9GF29
uniprot id: A0A8M1MML9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

29088:ARVCF
gene id: 29088:ARVCF
uniprot id: A0A2Y9H4I9
uniprot id: A0A2Y9H4K2
uniprot id: A0A2Y9H4L0
uniprot id: A0A8M1MYZ1
names: Similarity
messages: Belongs to the beta-catenin family.

29088:URM1
gene id: 29088:URM1
uniprot id: A0A2Y9HCF6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.
messages: Component of a complex at least composed of URM1, CTU2/NCS2 and CTU1/ATPBD3.
messages: Cytoplasm

29088:OSBPL10
gene id: 29088:OSBPL10
uniprot id: A0A2Y9G8L8
uniprot id: A0A2Y9G9P0
names: Similarity
messages: Belongs to the OSBP family.

29088:PTP4A2
gene id: 29088:PTP4A2
uniprot id: A0A2Y9GPS7
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

29088:LOC110574604
gene id: 29088:LOC110574604
uniprot id: A0A2Y9GIN5
uniprot id: A0A2Y9GIN7
uniprot id: A0A2Y9GM81
uniprot id: A0A2Y9GNX9
uniprot id: A0A8M1MFP0
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

29088:FUT4
gene id: 29088:FUT4
uniprot id: A0A2Y9G9D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

29088:SLC1A1
gene id: 29088:SLC1A1
uniprot id: A0A2Y9HKB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

29088:MARCHF4
gene id: 29088:MARCHF4
uniprot id: A0A8M1M9Y1
names: Subcellular Location Annotation
messages: Membrane

29088:ANTKMT
gene id: 29088:ANTKMT
uniprot id: A0A8M1MDP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

29088:SPDYA
gene id: 29088:SPDYA
uniprot id: A0A2Y9HN65
uniprot id: A0A2Y9HUU3
names: Similarity
messages: Belongs to the Speedy/Ringo family.

29088:ARRB2
gene id: 29088:ARRB2
uniprot id: A0A2Y9HL08
names: Similarity
messages: Belongs to the arrestin family.

29088:LOC110577479
gene id: 29088:LOC110577479
uniprot id: A0A2Y9GXD9
uniprot id: A0A2Y9GZ27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:FLVCR1
gene id: 29088:FLVCR1
uniprot id: A0A2Y9GGF4
names: Subcellular Location Annotation
messages: Membrane

29088:PRPS2
gene id: 29088:PRPS2
uniprot id: A0A8M1M2B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

29088:CLDN14
gene id: 29088:CLDN14
uniprot id: A0A2Y9G3P7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

29088:LOC110573517
gene id: 29088:LOC110573517
uniprot id: A0A2Y9GF63
names: Similarity
messages: Belongs to the S-100 family.

29088:PCNX2
gene id: 29088:PCNX2
uniprot id: A0A2Y9HQ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

29088:LOC110575025
gene id: 29088:LOC110575025
uniprot id: A0A8M1MG82
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:GRIK2
gene id: 29088:GRIK2
uniprot id: A0A2Y9HBZ8
uniprot id: A0A2Y9HIN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

29088:TNFSF11
gene id: 29088:TNFSF11
uniprot id: A0A2Y9HW80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

29088:PEX1
gene id: 29088:PEX1
uniprot id: A0A8M1MPS7
uniprot id: A0A8M1MRN6
uniprot id: A0A8M1MY30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: cytosol

29088:KIF25
gene id: 29088:KIF25
uniprot id: A0A2Y9HHK0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:BOC
gene id: 29088:BOC
uniprot id: A0A2Y9HEU4
names: Subcellular Location Annotation
messages: Cell membrane

29088:LOC110588857
gene id: 29088:LOC110588857
uniprot id: A0A8M1MPQ5
names: Similarity
messages: Belongs to the GroES chaperonin family.

29088:LOC110578045
gene id: 29088:LOC110578045
uniprot id: A0A8M1M9W5
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

29088:EXOC3L2
gene id: 29088:EXOC3L2
uniprot id: A0A8M1M0A9
names: Similarity
messages: Belongs to the SEC6 family.

29088:RSBN1L
gene id: 29088:RSBN1L
uniprot id: A0A2Y9H654
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the round spermatid basic protein 1 family.
messages: Nucleus

29088:TLR5
gene id: 29088:TLR5
uniprot id: A0A2Y9G7V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

29088:LOC110577063
gene id: 29088:LOC110577063
uniprot id: A0A8M1MVR0
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

29088:TAGLN3
gene id: 29088:TAGLN3
uniprot id: A0A2Y9H8W5
names: Similarity
messages: Belongs to the calponin family.

29088:BMP15
gene id: 29088:BMP15
uniprot id: A0A2Y9G675
names: Similarity
messages: Belongs to the TGF-beta family.

29088:RPS21
gene id: 29088:RPS21
uniprot id: A0A2Y9G6S2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the 40S small ribosomal subunit.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: cytosol

29088:SPSB4
gene id: 29088:SPSB4
uniprot id: A0A2Y9G9H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

29088:LOC110575554
gene id: 29088:LOC110575554
uniprot id: A0A8M1M5I7
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

29088:FOXC2
gene id: 29088:FOXC2
uniprot id: A0A2Y9I2H8
names: Subcellular Location Annotation
messages: Nucleus

29088:SDC1
gene id: 29088:SDC1
uniprot id: A0A2Y9HNZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

29088:TYMS
gene id: 29088:TYMS
uniprot id: A0A2Y9GRT1
uniprot id: A0A8M1MWN7
names: Similarity
messages: Belongs to the thymidylate synthase family.

29088:PKD2L2
gene id: 29088:PKD2L2
uniprot id: A0A2Y9I0Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Membrane

29088:GDF7
gene id: 29088:GDF7
uniprot id: A0A2Y9HVH5
names: Similarity
messages: Belongs to the TGF-beta family.

29088:LOC110586311
gene id: 29088:LOC110586311
uniprot id: A0A8M1MQ45
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

29088:ZDHHC16
gene id: 29088:ZDHHC16
uniprot id: A0A2Y9HUF5
uniprot id: A0A2Y9HZA5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

29088:SPO11
gene id: 29088:SPO11
uniprot id: A0A2Y9G332
uniprot id: A0A8M1MVA1
names: Similarity
messages: Belongs to the TOP6A family.

29088:PIK3C2A
gene id: 29088:PIK3C2A
uniprot id: A0A2Y9GNY5
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

29088:LOC110577359
gene id: 29088:LOC110577359
uniprot id: A0A2Y9GST9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRE11/RAD32 family.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
messages: Nucleus

29088:TMED5
gene id: 29088:TMED5
uniprot id: A0A2Y9H8S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

29088:CHMP7
gene id: 29088:CHMP7
uniprot id: A0A2Y9HS97
uniprot id: A0A8M1M3P7
names: Similarity
messages: Belongs to the SNF7 family.

29088:SMC4
gene id: 29088:SMC4
uniprot id: A0A2Y9I7W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family.
messages: Chromosome
messages: Nucleus

29088:CYRIA
gene id: 29088:CYRIA
uniprot id: A0A2Y9HNV1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CYRI family.
messages: Interacts with RAC1 (GTP-bound form preferentially).
messages: Membrane

29088:TARBP2
gene id: 29088:TARBP2
uniprot id: A0A2Y9GYY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TARBP2 family.
messages: Cytoplasm
messages: Nucleus
messages: Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1.
messages: Self-associates. Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Note that the trimeric RLC/miRLC is also referred to as RISC. Interacts with EIF2AK2/PKR and inhibits its protein kinase activity. Interacts with DHX9 and PRKRA. Interacts with DICER1, AGO2, MOV10, EIF6 and RPL7A (60S ribosome subunit); they form a large RNA-induced silencing complex (RISC).
messages: perinuclear region

29088:NADK2
gene id: 29088:NADK2
uniprot id: A0A2Y9HQD2
uniprot id: A0A8M1MIG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD kinase family.
messages: Homodimer.
messages: Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.
messages: Mitochondrion

29088:GDF6
gene id: 29088:GDF6
uniprot id: A0A2Y9H4Z6
names: Similarity
messages: Belongs to the TGF-beta family.

29088:NRDC
gene id: 29088:NRDC
uniprot id: A0A2Y9GQ52
names: Similarity
messages: Belongs to the peptidase M16 family.

29088:KRT19
gene id: 29088:KRT19
uniprot id: A0A2Y9GEM8
names: Similarity
messages: Belongs to the intermediate filament family.

29088:OTULINL
gene id: 29088:OTULINL
uniprot id: A0A2Y9I2L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

29088:RORB
gene id: 29088:RORB
uniprot id: A0A2Y9HKQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

29088:KCNK10
gene id: 29088:KCNK10
uniprot id: A0A8M1MMG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

29088:RUVBL2
gene id: 29088:RUVBL2
uniprot id: A0A2Y9GD51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

29088:LOC110589418
gene id: 29088:LOC110589418
uniprot id: A0A2Y9I229
names: Subcellular Location Annotation
messages: Nucleus

29088:ANKRD13B
gene id: 29088:ANKRD13B
uniprot id: A0A2Y9I8F1
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

29088:PYGM
gene id: 29088:PYGM
uniprot id: A0A2Y9GN55
uniprot id: A0A2Y9GN94
uniprot id: A0A2Y9GNG8
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

29088:RAB27A
gene id: 29088:RAB27A
uniprot id: A0A2Y9HCQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

29088:MARF1
gene id: 29088:MARF1
uniprot id: A0A8M1MG51
uniprot id: A0A8M1ML43
names: Subcellular Location Annotation
messages: Peroxisome

29088:TALDO1
gene id: 29088:TALDO1
uniprot id: A0A2Y9HEZ7
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

29088:HCN1
gene id: 29088:HCN1
uniprot id: A0A2Y9HH92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

29088:MS4A4A
gene id: 29088:MS4A4A
uniprot id: A0A2Y9GUI8
names: Similarity
messages: Belongs to the MS4A family.

29088:LOC110591629
gene id: 29088:LOC110591629
uniprot id: A0A2Y9I2P0
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor.
messages: Nucleus

29088:DAZAP2
gene id: 29088:DAZAP2
uniprot id: A0A2Y9I9H9
uniprot id: A0A2Y9I9K1
uniprot id: A0A8M1MBW8
uniprot id: A0A8M1MC17
uniprot id: A0A8M1MFJ1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus speckle
messages: nuclear body

29088:LOC110576431
gene id: 29088:LOC110576431
uniprot id: A0A2Y9GPT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110578665
gene id: 29088:LOC110578665
uniprot id: A0A8M1M0Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

29088:TMC4
gene id: 29088:TMC4
uniprot id: A0A8M1M080
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:ST8SIA5
gene id: 29088:ST8SIA5
uniprot id: A0A2Y9GRU9
uniprot id: A0A2Y9GRZ5
uniprot id: A0A2Y9GVY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

29088:CDH20
gene id: 29088:CDH20
uniprot id: A0A2Y9GS46
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

29088:NONO
gene id: 29088:NONO
uniprot id: A0A2Y9GB76
uniprot id: A0A2Y9GFH8
names: Subcellular Location Annotation
messages: Nucleus speckle

29088:SNRPN
gene id: 29088:SNRPN
uniprot id: A0A8M1MNM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP SmB/SmN family.
messages: Nucleus

29088:BAZ2A
gene id: 29088:BAZ2A
uniprot id: A0A8M1MFG7
names: Similarity
messages: Belongs to the WAL family.

29088:NAA40
gene id: 29088:NAA40
uniprot id: A0A2Y9GTS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

29088:EIF3D
gene id: 29088:EIF3D
uniprot id: A0A2Y9H0V6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit D family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Cytoplasm
messages: Phosphorylated upon DNA damage, probably by ATM or ATR.
messages: The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. In the eIF-3 complex, EIF3D specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

29088:ATP6V1B1
gene id: 29088:ATP6V1B1
uniprot id: A0A2Y9HTD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

29088:SEPTIN5
gene id: 29088:SEPTIN5
uniprot id: A0A2Y9H4J4
uniprot id: A0A2Y9H4K7
uniprot id: A0A2Y9H4L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

29088:PEBP1
gene id: 29088:PEBP1
uniprot id: A0A2Y9ICJ8
uniprot id: A0A8M1MW81
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

29088:NUP133
gene id: 29088:NUP133
uniprot id: A0A2Y9HPZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin Nup133 family.
messages: nuclear pore complex

29088:GREB1L
gene id: 29088:GREB1L
uniprot id: A0A2Y9GRT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GREB1 family.
messages: Membrane

29088:LOC110593638
gene id: 29088:LOC110593638
uniprot id: A0A2Y9IGP4
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110583928
gene id: 29088:LOC110583928
uniprot id: A0A2Y9HDD8
uniprot id: A0A2Y9HJM6
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:GPAT4
gene id: 29088:GPAT4
uniprot id: A0A2Y9GDZ6
uniprot id: A0A2Y9GE17
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

29088:LOC110577406
gene id: 29088:LOC110577406
uniprot id: A0A2Y9GX52
names: Similarity
messages: Belongs to the intermediate filament family.

29088:METAP1
gene id: 29088:METAP1
uniprot id: A0A2Y9GAR2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

29088:SCRN1
gene id: 29088:SCRN1
uniprot id: A0A2Y9H7X7
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

29088:RPL4
gene id: 29088:RPL4
uniprot id: A0A2Y9HCM6
uniprot id: A0A8M1MIU2
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

29088:SQLE
gene id: 29088:SQLE
uniprot id: A0A2Y9GYZ6
uniprot id: A0A2Y9GZ13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane

29088:LOC110579865
gene id: 29088:LOC110579865
uniprot id: A0A2Y9H0Z7
uniprot id: A0A8M1MY48
names: Similarity
messages: Belongs to the nucleoplasmin family.

29088:FYTTD1
gene id: 29088:FYTTD1
uniprot id: A0A2Y9H8I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UIF family.
messages: Nucleus speckle
messages: nucleoplasm

29088:HSD17B4
gene id: 29088:HSD17B4
uniprot id: A0A2Y9I0B9
uniprot id: A0A2Y9I0N7
uniprot id: A0A2Y9I5C4
uniprot id: A0A8M1MIX2
uniprot id: A0A8M1MP81
names: Subcellular Location Annotation
messages: Peroxisome

29088:LOC110577213
gene id: 29088:LOC110577213
uniprot id: A0A8M1MPE3
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

29088:THNSL2
gene id: 29088:THNSL2
uniprot id: A0A2Y9HV41
uniprot id: A0A8M1MVQ8
names: Similarity
messages: Belongs to the threonine synthase family.

29088:P2RY2
gene id: 29088:P2RY2
uniprot id: A0A2Y9I9F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:BHLHB9
gene id: 29088:BHLHB9
uniprot id: A0A2Y9H881
names: Similarity
messages: Belongs to the GPRASP family.

29088:CLDN2
gene id: 29088:CLDN2
uniprot id: A0A2Y9G476
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

29088:KRT32
gene id: 29088:KRT32
uniprot id: A0A2Y9GEH5
names: Similarity
messages: Belongs to the intermediate filament family.

29088:KRT82
gene id: 29088:KRT82
uniprot id: A0A2Y9GT13
names: Similarity
messages: Belongs to the intermediate filament family.

29088:CPLX1
gene id: 29088:CPLX1
uniprot id: A0A2Y9G5C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

29088:NDOR1
gene id: 29088:NDOR1
uniprot id: A0A2Y9H4T6
uniprot id: A0A2Y9H4V2
uniprot id: A0A2Y9HA71
uniprot id: A0A8M1MST6
uniprot id: A0A8M1MYE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Interacts with CIAPIN1; as part of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of CIAPIN1, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. It can also reduce the [2Fe-2S] cluster of CISD1 and activate this protein implicated in Fe/S cluster repair.
messages: perinuclear region

29088:LOC110585529
gene id: 29088:LOC110585529
uniprot id: A0A2Y9HP17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ALG6
gene id: 29088:ALG6
uniprot id: A0A2Y9G9K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:SGCD
gene id: 29088:SGCD
uniprot id: A0A2Y9HMQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

29088:ARSF
gene id: 29088:ARSF
uniprot id: A0A2Y9HNS5
names: Similarity
messages: Belongs to the sulfatase family.

29088:OLFML1
gene id: 29088:OLFML1
uniprot id: A0A2Y9GU66
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:KIF3C
gene id: 29088:KIF3C
uniprot id: A0A2Y9HN56
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:GAL3ST1
gene id: 29088:GAL3ST1
uniprot id: A0A2Y9I5H9
uniprot id: A0A2Y9I5R7
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

29088:TBXAS1
gene id: 29088:TBXAS1
uniprot id: A0A2Y9HA28
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:RETN
gene id: 29088:RETN
uniprot id: A0A2Y9IAX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistin/FIZZ family.
messages: Secreted

29088:DCTN2
gene id: 29088:DCTN2
uniprot id: A0A2Y9GUB0
uniprot id: A0A8M1ME23
uniprot id: A0A8M1MKC4
names: Similarity
messages: Belongs to the dynactin subunit 2 family.

29088:MMP2
gene id: 29088:MMP2
uniprot id: A0A2Y9I980
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: extracellular matrix

29088:MFSD14B
gene id: 29088:MFSD14B
uniprot id: A0A2Y9HKP1
uniprot id: A0A2Y9HKV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

29088:ZNF500
gene id: 29088:ZNF500
uniprot id: A0A8M1MJY9
names: Subcellular Location Annotation
messages: Nucleus

29088:OTOP2
gene id: 29088:OTOP2
uniprot id: A0A2Y9GC13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

29088:EFNB2
gene id: 29088:EFNB2
uniprot id: A0A2Y9HQA2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:ERMN
gene id: 29088:ERMN
uniprot id: A0A2Y9I9I0
uniprot id: A0A2Y9IBX8
names: Function
names: Subunit
messages: Binds actin.
messages: Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS.

29088:OSBPL5
gene id: 29088:OSBPL5
uniprot id: A0A8M1MQM7
names: Similarity
messages: Belongs to the OSBP family.

29088:TMEM132E
gene id: 29088:TMEM132E
uniprot id: A0A8M1MV65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

29088:ACTN3
gene id: 29088:ACTN3
uniprot id: A0A2Y9GNG5
names: Similarity
messages: Belongs to the alpha-actinin family.

29088:LOC110585369
gene id: 29088:LOC110585369
uniprot id: A0A8M1MN52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110592234
gene id: 29088:LOC110592234
uniprot id: A0A2Y9I4K0
uniprot id: A0A2Y9I577
names: Similarity
messages: Belongs to the SEN15 family.

29088:LOC110570839
gene id: 29088:LOC110570839
uniprot id: A0A2Y9G6B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP receptor beta subunit family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:LOC110570538
gene id: 29088:LOC110570538
uniprot id: A0A2Y9G7W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:NPPA
gene id: 29088:NPPA
uniprot id: A0A2Y9GP71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the natriuretic peptide family.
messages: Cell projection
messages: Homodimer; disulfide-linked antiparallel dimer.
messages: Hormone produced in the kidneys that appears to be important for maintaining cardio-renal homeostasis. Mediates vasodilation, natriuresis and diuresis primarily in the renal system, in order to maintain the extracellular fluid volume and control the fluid-electrolyte balance. Specifically binds and stimulates cGMP production by renal transmembrane receptors, likely NPR1. Urodilatin not ANP, may be the natriuretic peptide responsible for the regulation of sodium and water homeostasis in the kidney.
messages: May have a role in cardio-renal homeostasis through regulation of diuresis and inhibiting aldosterone synthesis. In vitro, promotes the production of cGMP and induces vasodilation. May promote natriuresis, at least in part, by enhancing prostaglandin E2 synthesis resulting in the inhibition of renal Na+-K+-ATPase. May have a role in potassium excretion but not sodium excretion (natriuresis). Possibly enhances protein excretion in urine by decreasing proximal tubular protein reabsorption.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis and vasodilation. In vivo promotes natriuresis and in vitro, vasodilates renal artery strips.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis and vasodilation. In vivo promotes natriuresis. In vitro, selectively vasodilates intestinal and vascular smooth muscle strips.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis and vasodilation. In vivo promotes natriuresis. In vitro, selectively vasodilates intestinal smooth muscle but not vascular smooth muscle strips.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis, diuresis, and vasodilation. In vitro, promotes the production of cGMP and induces vasodilation. May promote natriuresis, at least in part, by enhancing prostaglandin E2 synthesis resulting in the inhibition of renal Na+-K+-ATPase. However reports on the involvement of this peptide in mammal blood volume and blood pressure homeostasis are conflicting; according to a report it is not sufficient to activate cGMP and does not inhibit collecting duct transport nor effect diuresis and natriuresis. Appears to bind to specific receptors that are distinct from the receptors bound by the atrial natriuretic and long-acting natriuretic peptides. Possibly functions in protein excretion in urine by maintaining the integrity of the proximal tubules and enhancing protein excretion by decreasing proximal tubular protein reabsorption.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis, diuresis, vasodilation, and inhibiting aldosterone synthesis. In vitro, promotes the production of cGMP and induces vasodilation. May promote natriuresis, at least in part, by enhancing prostaglandin E2 synthesis resulting in the inhibition of renal Na+-K+-ATPase (By similarity). However reports on the involvement of this peptide in mammal blood volume and blood pressure homeostasis are conflicting; according to a report, in vivo it is not sufficient to activate cGMP and does not inhibit collecting duct transport nor effect diuresis and natriuresis (By similarity). Appears to bind to specific receptors that are distinct from the receptors bound by atrial natriuretic peptide and vessel dilator. Possibly enhances protein excretion in urine by decreasing proximal tubular protein reabsorption.
messages: May have a role in cardio-renal homeostasis through regulation of regulation of natriuresis and vasodilation. In vivo promotes natriuresis. In vitro, vasodilates intestinal smooth muscle but not smooth muscle strips.
messages: Secreted

29088:CETN1
gene id: 29088:CETN1
uniprot id: A0A2Y9GRJ1
names: Similarity
messages: Belongs to the centrin family.

29088:LOC110583809
gene id: 29088:LOC110583809
uniprot id: A0A8M1M8Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

29088:TM9SF4
gene id: 29088:TM9SF4
uniprot id: A0A2Y9H490
uniprot id: A0A8M1MKT4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:LOC110588821
gene id: 29088:LOC110588821
uniprot id: A0A8M1MQ04
uniprot id: A0A8M1MVX1
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

29088:TEKT1
gene id: 29088:TEKT1
uniprot id: A0A2Y9HFR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

29088:HCRTR1
gene id: 29088:HCRTR1
uniprot id: A0A2Y9GN16
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:ERH
gene id: 29088:ERH
uniprot id: A0A2Y9GAR6
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

29088:TMEM86B
gene id: 29088:TMEM86B
uniprot id: A0A2Y9GFJ7
uniprot id: A0A2Y9GFQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

29088:LOC110592553
gene id: 29088:LOC110592553
uniprot id: A0A8M1MTE4
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

29088:TMX2
gene id: 29088:TMX2
uniprot id: A0A2Y9GN18
uniprot id: A0A8M1MMU1
uniprot id: A0A8M1MPS6
uniprot id: A0A8M1MR50
uniprot id: A0A8M1MWZ1
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum and mitochondria-associated protein that probably functions as a regulator of cellular redox state and thereby regulates protein post-translational modification, protein folding and mitochondrial activity. Indirectly regulates neuronal proliferation, migration, and organization in the developing brain.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

29088:LOC110586384
gene id: 29088:LOC110586384
uniprot id: A0A2Y9HKR4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

29088:B3GAT1
gene id: 29088:B3GAT1
uniprot id: A0A2Y9HK74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:POLR2D
gene id: 29088:POLR2D
uniprot id: A0A2Y9HIQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

29088:LOC110572167
gene id: 29088:LOC110572167
uniprot id: A0A8M1MMR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

29088:HGF
gene id: 29088:HGF
uniprot id: A0A2Y9H1Q2
uniprot id: A0A2Y9H6M8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Dimer of an alpha chain and a beta chain linked by a disulfide bond. Interacts with SRPX2; the interaction increases HGF mitogenic activity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.

29088:LOC110583429
gene id: 29088:LOC110583429
uniprot id: A0A2Y9HBU4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

29088:SAMD4A
gene id: 29088:SAMD4A
uniprot id: A0A2Y9HZI5
uniprot id: A0A2Y9HZT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

29088:P2RX5
gene id: 29088:P2RX5
uniprot id: A0A2Y9I6V5
uniprot id: A0A2Y9IBM6
uniprot id: A0A2Y9IEB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

29088:ARL11
gene id: 29088:ARL11
uniprot id: A0A2Y9H0S7
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

29088:AGBL5
gene id: 29088:AGBL5
uniprot id: A0A2Y9HUI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Midbody
messages: Nucleus
messages: cytosol
messages: spindle

29088:SLX9
gene id: 29088:SLX9
uniprot id: A0A2Y9G708
uniprot id: A0A2Y9G7C7
uniprot id: A0A8M1M618
uniprot id: A0A8M1M860
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLX9 family.
messages: nucleolus

29088:TCL1A
gene id: 29088:TCL1A
uniprot id: A0A2Y9GBZ5
names: Similarity
messages: Belongs to the TCL1 family.

29088:ERCC4
gene id: 29088:ERCC4
uniprot id: A0A2Y9HQ83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPF family.
messages: Nucleus

29088:KRT38
gene id: 29088:KRT38
uniprot id: A0A2Y9GE92
names: Similarity
messages: Belongs to the intermediate filament family.

29088:G6PC2
gene id: 29088:G6PC2
uniprot id: A0A2Y9I4T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

29088:ITPR3
gene id: 29088:ITPR3
uniprot id: A0A8M1MIA0
uniprot id: A0A8M1MLN4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

29088:RCAN2
gene id: 29088:RCAN2
uniprot id: A0A2Y9HDH2
uniprot id: A0A2Y9HEN3
names: Function
names: Similarity
messages: Belongs to the RCAN family.
messages: Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.

29088:ARRB1
gene id: 29088:ARRB1
uniprot id: A0A2Y9I8Q5
names: Similarity
messages: Belongs to the arrestin family.

29088:MRPL22
gene id: 29088:MRPL22
uniprot id: A0A2Y9HML5
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

29088:GNG7
gene id: 29088:GNG7
uniprot id: A0A8M1MPE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

29088:FA2H
gene id: 29088:FA2H
uniprot id: A0A2Y9I8S3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis. Involved in the synthesis of sphingolipids of plasma membrane rafts, controlling lipid raft mobility and trafficking of raft-associated proteins.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:ELF3
gene id: 29088:ELF3
uniprot id: A0A2Y9GJI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

29088:PLXNA3
gene id: 29088:PLXNA3
uniprot id: A0A8M1M1T4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:PPP3CC
gene id: 29088:PPP3CC
uniprot id: A0A2Y9HSH1
uniprot id: A0A2Y9HXV8
uniprot id: A0A2Y9HZE9
uniprot id: A0A8M1M6Y4
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

29088:LOC110578153
gene id: 29088:LOC110578153
uniprot id: A0A8M1MD01
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

29088:B4GALT1
gene id: 29088:B4GALT1
uniprot id: A0A2Y9H5V8
uniprot id: A0A8M1MRL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

29088:LOC110584580
gene id: 29088:LOC110584580
uniprot id: A0A2Y9HF09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCO1/2 family.
messages: Mitochondrion inner membrane

29088:LOC110580807
gene id: 29088:LOC110580807
uniprot id: A0A8M1MBA6
names: Subcellular Location Annotation
messages: Membrane

29088:TAS1R1
gene id: 29088:TAS1R1
uniprot id: A0A2Y9GLI5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:LOC110574960
gene id: 29088:LOC110574960
uniprot id: A0A2Y9GJW0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110577821
gene id: 29088:LOC110577821
uniprot id: A0A2Y9GUN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

29088:NMD3
gene id: 29088:NMD3
uniprot id: A0A2Y9I316
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

29088:GLS2
gene id: 29088:GLS2
uniprot id: A0A2Y9GYQ4
names: Similarity
messages: Belongs to the glutaminase family.

29088:OCLN
gene id: 29088:OCLN
uniprot id: A0A2Y9HWF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
messages: Membrane
messages: tight junction

29088:LOC110585952
gene id: 29088:LOC110585952
uniprot id: A0A8M1MGE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

29088:MFN1
gene id: 29088:MFN1
uniprot id: A0A8M1MTK1
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

29088:LOC110583433
gene id: 29088:LOC110583433
uniprot id: A0A8M1MHV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL27 family.
messages: Endoplasmic reticulum

29088:LOC110586215
gene id: 29088:LOC110586215
uniprot id: A0A2Y9HRN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:INTS12
gene id: 29088:INTS12
uniprot id: A0A2Y9GD96
names: Similarity
names: Subunit
messages: Belongs to the Integrator subunit 12 family.
messages: Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, INTS11/CPSF3L and INTS12.

29088:RECQL
gene id: 29088:RECQL
uniprot id: A0A2Y9H8L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

29088:OLFM3
gene id: 29088:OLFM3
uniprot id: A0A2Y9H2F8
uniprot id: A0A2Y9H7F6
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

29088:SEC22C
gene id: 29088:SEC22C
uniprot id: A0A8M1MLW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

29088:TM4SF18
gene id: 29088:TM4SF18
uniprot id: A0A2Y9GQY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

29088:YEATS2
gene id: 29088:YEATS2
uniprot id: A0A2Y9H8V4
names: Subcellular Location Annotation
messages: Nucleus

29088:REM1
gene id: 29088:REM1
uniprot id: A0A2Y9H6H3
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

29088:HSCB
gene id: 29088:HSCB
uniprot id: A0A2Y9I676
names: Similarity
messages: Belongs to the HscB family.

29088:SEC23B
gene id: 29088:SEC23B
uniprot id: A0A2Y9HXN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

29088:ATG12
gene id: 29088:ATG12
uniprot id: A0A2Y9I1I7
uniprot id: A0A2Y9I205
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATG12 family.
messages: Forms a conjugate with ATG5.
messages: Ubiquitin-like protein involved in autophagic vesicle formation.

29088:FLT4
gene id: 29088:FLT4
uniprot id: A0A2Y9H8L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

29088:ATP6V0E1
gene id: 29088:ATP6V0E1
uniprot id: A0A2Y9HVY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

29088:MALL
gene id: 29088:MALL
uniprot id: A0A2Y9HNL9
names: Subcellular Location Annotation
messages: Membrane

29088:AIMP2
gene id: 29088:AIMP2
uniprot id: A0A2Y9GA08
uniprot id: A0A2Y9GDP8
uniprot id: A0A8M1MBD7
uniprot id: A0A8M1MEV5
uniprot id: A0A8M1MJQ0
names: Subcellular Location Annotation
messages: Nucleus
messages: cytosol

29088:ST3GAL2
gene id: 29088:ST3GAL2
uniprot id: A0A2Y9IBF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

29088:LOC110591984
gene id: 29088:LOC110591984
uniprot id: A0A8M1M627
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion membrane

29088:NPEPL1
gene id: 29088:NPEPL1
uniprot id: A0A2Y9G6T3
uniprot id: A0A8M1MLK2
names: Similarity
messages: Belongs to the peptidase M17 family.

29088:RPL22
gene id: 29088:RPL22
uniprot id: A0A2Y9GP08
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

29088:LOC110571204
gene id: 29088:LOC110571204
uniprot id: A0A2Y9GB37
names: Caution
names: Similarity
messages: Belongs to the HHIP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:APOC1
gene id: 29088:APOC1
uniprot id: A0A2Y9GD53
uniprot id: A0A2Y9GG65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C1 family.
messages: Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.
messages: Secreted

29088:GPC4
gene id: 29088:GPC4
uniprot id: A0A2Y9GQ42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

29088:FZD4
gene id: 29088:FZD4
uniprot id: A0A2Y9GSD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Membrane

29088:SMG5
gene id: 29088:SMG5
uniprot id: A0A2Y9GF42
uniprot id: A0A8M1MD78
uniprot id: A0A8M1MDC7
uniprot id: A0A8M1MFE5
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays a role in nonsense-mediated mRNA decay.

29088:TRAPPC4
gene id: 29088:TRAPPC4
uniprot id: A0A2Y9HJW0
uniprot id: A0A8M1MN35
uniprot id: A0A8M1MN39
uniprot id: A0A8M1MQ16
uniprot id: A0A8M1MX53
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

29088:LOC110593924
gene id: 29088:LOC110593924
uniprot id: A0A2Y9II09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:TBCE
gene id: 29088:TBCE
uniprot id: A0A2Y9HJL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCE family.
messages: Cytoplasm

29088:TGFB1I1
gene id: 29088:TGFB1I1
uniprot id: A0A2Y9I400
uniprot id: A0A8M1MEX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paxillin family.
messages: cytoskeleton
messages: focal adhesion

29088:KRT36
gene id: 29088:KRT36
uniprot id: A0A2Y9GIU2
names: Similarity
messages: Belongs to the intermediate filament family.

29088:IL17C
gene id: 29088:IL17C
uniprot id: A0A2Y9IAP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

29088:RPP30
gene id: 29088:RPP30
uniprot id: A0A2Y9HZW2
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

29088:PCYOX1
gene id: 29088:PCYOX1
uniprot id: A0A2Y9HTD1
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

29088:VANGL2
gene id: 29088:VANGL2
uniprot id: A0A2Y9GEP7
uniprot id: A0A2Y9GET7
uniprot id: A0A8M1MN48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

29088:EXTL3
gene id: 29088:EXTL3
uniprot id: A0A2Y9HSQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:LOC110593571
gene id: 29088:LOC110593571
uniprot id: A0A8M1MB96
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:HYAL3
gene id: 29088:HYAL3
uniprot id: A0A2Y9GTR8
uniprot id: A0A2Y9GTX9
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

29088:RUNX2
gene id: 29088:RUNX2
uniprot id: A0A2Y9H7B2
uniprot id: A0A2Y9H7B8
uniprot id: A0A2Y9H7I7
uniprot id: A0A2Y9HCY2
uniprot id: A0A2Y9HE63
uniprot id: A0A8M1MHH4
names: Function
names: Subcellular Location Annotation
messages: Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
messages: Nucleus

29088:STARD13
gene id: 29088:STARD13
uniprot id: A0A2Y9G503
names: Subcellular Location Annotation
messages: Cytoplasm

29088:PRDX6
gene id: 29088:PRDX6
uniprot id: A0A2Y9GGK9
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

29088:LOC110582951
gene id: 29088:LOC110582951
uniprot id: A0A2Y9HAH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:RAB33A
gene id: 29088:RAB33A
uniprot id: A0A2Y9GVV9
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

29088:OPRK1
gene id: 29088:OPRK1
uniprot id: A0A2Y9GXJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.
messages: Interacts with NHERF1. Interacts with GABARAPL1.
messages: Membrane

29088:MANEA
gene id: 29088:MANEA
uniprot id: A0A2Y9HHE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:CALHM6
gene id: 29088:CALHM6
uniprot id: A0A2Y9HCD3
uniprot id: A0A8M1MS19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

29088:GPRC5D
gene id: 29088:GPRC5D
uniprot id: A0A2Y9H487
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:LOC110580102
gene id: 29088:LOC110580102
uniprot id: A0A2Y9H1J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

29088:CTNNB1
gene id: 29088:CTNNB1
uniprot id: A0A2Y9G4Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: adherens junction

29088:RPL36AL
gene id: 29088:RPL36AL
uniprot id: A0A2Y9I4I3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

29088:APOOL
gene id: 29088:APOOL
uniprot id: A0A2Y9HC28
uniprot id: A0A2Y9HD84
uniprot id: A0A8M1M914
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

29088:LOC123325521
gene id: 29088:LOC123325521
uniprot id: A0A2Y9H3T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:BMPR1B
gene id: 29088:BMPR1B
uniprot id: A0A2Y9GDC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

29088:ALKBH1
gene id: 29088:ALKBH1
uniprot id: A0A2Y9G8C6
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

29088:LOC110582501
gene id: 29088:LOC110582501
uniprot id: A0A2Y9H922
uniprot id: A0A2Y9H957
uniprot id: A0A2Y9H9A7
names: Subcellular Location Annotation
messages: Cell membrane

29088:ATXN1
gene id: 29088:ATXN1
uniprot id: A0A2Y9HSI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

29088:IL1R2
gene id: 29088:IL1R2
uniprot id: A0A2Y9GAC7
uniprot id: A0A2Y9GAH0
uniprot id: A0A2Y9GD18
names: Subcellular Location Annotation
messages: Cell membrane

29088:XCL1
gene id: 29088:XCL1
uniprot id: A0A2Y9GHG3
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Belongs to the intercrine gamma family.

29088:AGL
gene id: 29088:AGL
uniprot id: A0A2Y9H7T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

29088:VKORC1
gene id: 29088:VKORC1
uniprot id: A0A2Y9HX69
uniprot id: A0A2Y9I278
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:DPYD
gene id: 29088:DPYD
uniprot id: A0A2Y9H2S6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.
messages: Binds 4 [4Fe-4S] clusters. Contains approximately 16 iron atoms per subunit.
messages: Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine.

29088:SFRP1
gene id: 29088:SFRP1
uniprot id: A0A2Y9GDP6
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:DKK3
gene id: 29088:DKK3
uniprot id: A0A2Y9GP47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

29088:POPDC3
gene id: 29088:POPDC3
uniprot id: A0A2Y9HBJ1
names: Similarity
messages: Belongs to the popeye family.

29088:TMA7
gene id: 29088:TMA7
uniprot id: A0A2Y9IJE9
names: Similarity
messages: Belongs to the TMA7 family.

29088:CTTNBP2
gene id: 29088:CTTNBP2
uniprot id: A0A2Y9HTB8
names: Subcellular Location Annotation
messages: cell cortex
messages: dendritic spine

29088:ABT1
gene id: 29088:ABT1
uniprot id: A0A2Y9HRX3
uniprot id: A0A2Y9HT06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: nucleolus

29088:TMEM126A
gene id: 29088:TMEM126A
uniprot id: A0A2Y9GSE4
names: Subcellular Location Annotation
messages: Membrane

29088:MPPED1
gene id: 29088:MPPED1
uniprot id: A0A2Y9H249
names: Similarity
messages: Belongs to the UPF0046 family.

29088:SNPH
gene id: 29088:SNPH
uniprot id: A0A2Y9H6R8
names: Subcellular Location Annotation
messages: Membrane

29088:VPS4A
gene id: 29088:VPS4A
uniprot id: A0A2Y9I5M4
uniprot id: A0A2Y9I9T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

29088:MRPL33
gene id: 29088:MRPL33
uniprot id: A0A2Y9HN03
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

29088:SEC31B
gene id: 29088:SEC31B
uniprot id: A0A2Y9HZS1
uniprot id: A0A8M1MHI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: Endoplasmic reticulum membrane

29088:HCRT
gene id: 29088:HCRT
uniprot id: A0A2Y9GH97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the orexin family.
messages: Endoplasmic reticulum
messages: Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested.
messages: Rough endoplasmic reticulum
messages: Synapse
messages: Vesicle

29088:AP4S1
gene id: 29088:AP4S1
uniprot id: A0A2Y9HI34
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

29088:GPNMB
gene id: 29088:GPNMB
uniprot id: A0A2Y9H640
uniprot id: A0A8M1MQA8
names: Similarity
messages: Belongs to the PMEL/NMB family.

29088:MFGE8
gene id: 29088:MFGE8
uniprot id: A0A2Y9GF97
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:SMCO2
gene id: 29088:SMCO2
uniprot id: A0A2Y9H8H2
names: Subcellular Location Annotation
messages: Membrane

29088:PPP6C
gene id: 29088:PPP6C
uniprot id: A0A2Y9H766
uniprot id: A0A2Y9HDV4
uniprot id: A0A8M1MYP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

29088:LOC110576094
gene id: 29088:LOC110576094
uniprot id: A0A2Y9GNY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:TRIP12
gene id: 29088:TRIP12
uniprot id: A0A2Y9GL27
uniprot id: A0A8M1MFG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPL family. K-HECT subfamily.
messages: E3 ubiquitin-protein ligase involved in ubiquitin fusion degradation (UFD) pathway and regulation of DNA repair. Part of the ubiquitin fusion degradation (UFD) pathway, a process that mediates ubiquitination of protein at their N-terminus, regardless of the presence of lysine residues in target proteins.
messages: nucleoplasm

29088:BLM
gene id: 29088:BLM
uniprot id: A0A8M1MK72
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

29088:TSR1
gene id: 29088:TSR1
uniprot id: A0A2Y9I754
names: Subcellular Location Annotation
messages: nucleolus

29088:SERPINB7
gene id: 29088:SERPINB7
uniprot id: A0A2Y9GRA9
names: Similarity
messages: Belongs to the serpin family.

29088:LOC110593471
gene id: 29088:LOC110593471
uniprot id: A0A2Y9IG84
names: Subcellular Location Annotation
messages: Nucleus

29088:CFL2
gene id: 29088:CFL2
uniprot id: A0A2Y9HNL0
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

29088:GCNT1
gene id: 29088:GCNT1
uniprot id: A0A2Y9H578
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

29088:PFN3
gene id: 29088:PFN3
uniprot id: A0A2Y9HYQ9
names: Similarity
messages: Belongs to the profilin family.

29088:GLP2R
gene id: 29088:GLP2R
uniprot id: A0A2Y9HKX7
names: Subcellular Location Annotation
messages: Membrane

29088:AMIGO1
gene id: 29088:AMIGO1
uniprot id: A0A2Y9H2S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. AMIGO family.
messages: Membrane

29088:ZDHHC22
gene id: 29088:ZDHHC22
uniprot id: A0A2Y9GAY0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

29088:LOC110587118
gene id: 29088:LOC110587118
uniprot id: A0A2Y9HMV9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with chaperones HSP70 and HSP90; this interaction is required for initial targeting to mitochondria.
messages: Membrane
messages: Microsome membrane
messages: Mitochondrion inner membrane
messages: The omega-1 hydroxylase activity is stimulated by cytochrome b5.

29088:CDK2
gene id: 29088:CDK2
uniprot id: A0A2Y9GUJ7
uniprot id: A0A8M1MA38
uniprot id: A0A8M1MDU3
uniprot id: A0A8M1MIK0
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:LOC110582141
gene id: 29088:LOC110582141
uniprot id: A0A8M1MHX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

29088:CSTF3
gene id: 29088:CSTF3
uniprot id: A0A2Y9GP12
names: Subcellular Location Annotation
messages: Nucleus

29088:ELOVL6
gene id: 29088:ELOVL6
uniprot id: A0A2Y9GQT4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL6 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.

29088:CENPV
gene id: 29088:CENPV
uniprot id: A0A8M1MV51
names: Similarity
messages: Belongs to the Gfa family.

29088:PDGFRL
gene id: 29088:PDGFRL
uniprot id: A0A2Y9HJU6
names: Subunit
messages: Forms a complex composed of PDGFRL, TNK2 and GRB2.

29088:WRNIP1
gene id: 29088:WRNIP1
uniprot id: A0A2Y9HLI7
uniprot id: A0A8M1MI68
uniprot id: A0A8M1MS55
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

29088:LOC123326636
gene id: 29088:LOC123326636
uniprot id: A0A8M1MTH1
names: Subcellular Location Annotation
messages: Nucleus

29088:CPD
gene id: 29088:CPD
uniprot id: A0A2Y9I8M4
names: Similarity
messages: Belongs to the peptidase M14 family.

29088:RPS24
gene id: 29088:RPS24
uniprot id: A0A2Y9HUR8
uniprot id: A0A2Y9I133
uniprot id: A0A8M1MF10
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

29088:ENO1
gene id: 29088:ENO1
uniprot id: A0A2Y9GP72
uniprot id: A0A8M1MHB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

29088:ANXA11
gene id: 29088:ANXA11
uniprot id: A0A2Y9I178
uniprot id: A0A8M1MDU4
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

29088:LOC110576807
gene id: 29088:LOC110576807
uniprot id: A0A8M1M4I4
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

29088:LOC110576049
gene id: 29088:LOC110576049
uniprot id: A0A2Y9GNT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GST superfamily. Pi family.
messages: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
messages: Cytoplasm
messages: Homodimer.
messages: Mitochondrion
messages: Nucleus

29088:PIK3R1
gene id: 29088:PIK3R1
uniprot id: A0A2Y9I1U1
uniprot id: A0A2Y9I6H0
uniprot id: A0A2Y9I8L3
uniprot id: A0A8M1MPX6
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

29088:MRPS15
gene id: 29088:MRPS15
uniprot id: A0A2Y9GJW6
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

29088:UBR1
gene id: 29088:UBR1
uniprot id: A0A2Y9HI55
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

29088:PKIG
gene id: 29088:PKIG
uniprot id: A0A2Y9GZB1
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

29088:LXN
gene id: 29088:LXN
uniprot id: A0A2Y9I3B1
names: Similarity
messages: Belongs to the protease inhibitor I47 (latexin) family.

29088:NOTO
gene id: 29088:NOTO
uniprot id: A0A2Y9HT97
names: Subcellular Location Annotation
messages: Nucleus

29088:SMOC1
gene id: 29088:SMOC1
uniprot id: A0A2Y9G832
uniprot id: A0A2Y9GAS1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:RBP5
gene id: 29088:RBP5
uniprot id: A0A2Y9HAN9
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Belongs to the calycin superfamily. Lipocalin family.

29088:NEFL
gene id: 29088:NEFL
uniprot id: A0A2Y9HS86
names: Similarity
messages: Belongs to the intermediate filament family.

29088:PPM1L
gene id: 29088:PPM1L
uniprot id: A0A8M1MTR8
names: Similarity
messages: Belongs to the PP2C family.

29088:TOMM40
gene id: 29088:TOMM40
uniprot id: A0A2Y9GD92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

29088:CNOT8
gene id: 29088:CNOT8
uniprot id: A0A2Y9HMQ0
uniprot id: A0A2Y9HN12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

29088:OGT
gene id: 29088:OGT
uniprot id: A0A2Y9GBG9
uniprot id: A0A8M1M1P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.
messages: Cell projection
messages: Mitochondrion membrane

29088:NRG4
gene id: 29088:NRG4
uniprot id: A0A8M1MK59
names: Caution
names: Similarity
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:PYY
gene id: 29088:PYY
uniprot id: A0A2Y9GH40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

29088:LOC110571313
gene id: 29088:LOC110571313
uniprot id: A0A8M1M962
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

29088:TTC19
gene id: 29088:TTC19
uniprot id: A0A8M1MTX9
names: Similarity
messages: Belongs to the TTC19 family.

29088:PPP1R21
gene id: 29088:PPP1R21
uniprot id: A0A8M1MP51
uniprot id: A0A8M1MQF6
uniprot id: A0A8M1MWE0
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

29088:SLC35C1
gene id: 29088:SLC35C1
uniprot id: A0A2Y9GMK9
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110591261
gene id: 29088:LOC110591261
uniprot id: A0A2Y9I1Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

29088:MRPL4
gene id: 29088:MRPL4
uniprot id: A0A2Y9IHE1
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

29088:HTR6
gene id: 29088:HTR6
uniprot id: A0A2Y9GJ60
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:SLC7A8
gene id: 29088:SLC7A8
uniprot id: A0A2Y9HHE2
uniprot id: A0A2Y9HNN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Cell membrane
messages: Membrane

29088:LOC110590331
gene id: 29088:LOC110590331
uniprot id: A0A2Y9HYQ4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

29088:CLCN4
gene id: 29088:CLCN4
uniprot id: A0A2Y9GR53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

29088:LOC110592612
gene id: 29088:LOC110592612
uniprot id: A0A2Y9IAP2
uniprot id: A0A8M1MSF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

29088:LOC110585923
gene id: 29088:LOC110585923
uniprot id: A0A8M1M5P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRB/QCR7 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

29088:ACBD5
gene id: 29088:ACBD5
uniprot id: A0A2Y9GU36
uniprot id: A0A2Y9GU98
uniprot id: A0A2Y9H013
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.
messages: Belongs to the ATG37 family.
messages: Membrane
messages: Peroxisome membrane

29088:GKAP1
gene id: 29088:GKAP1
uniprot id: A0A8M1MT87
names: Similarity
messages: Belongs to the GKAP1 family.

29088:ITGAE
gene id: 29088:ITGAE
uniprot id: A0A8M1MZ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

29088:EIF4A3
gene id: 29088:EIF4A3
uniprot id: A0A2Y9GBY0
names: Similarity
messages: Belongs to the DEAD box helicase family.

29088:GIMAP7
gene id: 29088:GIMAP7
uniprot id: A0A2Y9HAC7
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

29088:PLA2G4D
gene id: 29088:PLA2G4D
uniprot id: A0A2Y9HI40
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

29088:LOC110569914
gene id: 29088:LOC110569914
uniprot id: A0A2Y9G3B6
uniprot id: A0A2Y9G3E6
uniprot id: A0A2Y9G3F1
uniprot id: A0A2Y9G3W6
uniprot id: A0A2Y9G5W1
uniprot id: A0A2Y9G722
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

29088:BTN1A1
gene id: 29088:BTN1A1
uniprot id: A0A2Y9HLH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

29088:RNASEH2B
gene id: 29088:RNASEH2B
uniprot id: A0A2Y9H0L1
uniprot id: A0A2Y9H5E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H2 subunit B family.
messages: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Nucleus
messages: The RNase H2 complex is a heterotrimer composed of the catalytic subunit RNASEH2A and the non-catalytic subunits RNASEH2B and RNASEH2C.

29088:UTP25
gene id: 29088:UTP25
uniprot id: A0A2Y9GGE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP25 family.
messages: nucleolus

29088:CAMK2A
gene id: 29088:CAMK2A
uniprot id: A0A2Y9HLY1
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

29088:FHIP2A
gene id: 29088:FHIP2A
uniprot id: A0A2Y9I1S5
names: Similarity
messages: Belongs to the FHIP family.

29088:BCL2
gene id: 29088:BCL2
uniprot id: A0A2Y9GS51
uniprot id: A0A2Y9GS89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: Nucleus membrane

29088:CTU2
gene id: 29088:CTU2
uniprot id: A0A2Y9ICB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTU2/NCS2 family.
messages: Component of a complex at least composed of URM1, CTU2/NCS2 and CTU1/ATPBD3.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

29088:PKM
gene id: 29088:PKM
uniprot id: A0A2Y9HD86
uniprot id: A0A8M1MJM7
uniprot id: A0A8M1MJM9
names: Similarity
messages: Belongs to the pyruvate kinase family.

29088:NDUFS5
gene id: 29088:NDUFS5
uniprot id: A0A2Y9GJR0
uniprot id: A0A2Y9GNC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Membrane
messages: Mitochondrion inner membrane

29088:ARAP3
gene id: 29088:ARAP3
uniprot id: A0A2Y9I0X1
names: Subcellular Location Annotation
messages: Cytoplasm

29088:FAM162B
gene id: 29088:FAM162B
uniprot id: A0A2Y9HHY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0389 family.
messages: Membrane

29088:PIGN
gene id: 29088:PIGN
uniprot id: A0A2Y9GS10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
messages: Membrane

29088:LOC110582558
gene id: 29088:LOC110582558
uniprot id: A0A2Y9H979
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

29088:NEUROD1
gene id: 29088:NEUROD1
uniprot id: A0A2Y9I4I6
names: Subcellular Location Annotation
messages: Nucleus

29088:HDHD2
gene id: 29088:HDHD2
uniprot id: A0A8M1MSM5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

29088:CLN8
gene id: 29088:CLN8
uniprot id: A0A2Y9HDQ5
names: Subcellular Location Annotation
messages: Membrane

29088:TSR3
gene id: 29088:TSR3
uniprot id: A0A2Y9HQM1
uniprot id: A0A2Y9HVW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1248 (Psi1248) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110581820
gene id: 29088:LOC110581820
uniprot id: A0A2Y9H6T7
uniprot id: A0A2Y9HCE2
names: Similarity
messages: Belongs to the AAA ATPase family.

29088:XNDC1N
gene id: 29088:XNDC1N
uniprot id: A0A2Y9IG20
names: Subcellular Location Annotation
messages: Membrane

29088:DONSON
gene id: 29088:DONSON
uniprot id: A0A2Y9G6G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DONSON family.
messages: Nucleus

29088:LOC110593569
gene id: 29088:LOC110593569
uniprot id: A0A8M1MAA3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110590311
gene id: 29088:LOC110590311
uniprot id: A0A8M1MXN4
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

29088:SLC24A2
gene id: 29088:SLC24A2
uniprot id: A0A2Y9GG54
uniprot id: A0A2Y9GG74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

29088:IRAK4
gene id: 29088:IRAK4
uniprot id: A0A2Y9I997
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with MYD88 and IRAK2 to form a ternary complex called the Myddosome.
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Cytoplasm
messages: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens.

29088:GJA10
gene id: 29088:GJA10
uniprot id: A0A2Y9HIK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

29088:FAM72A
gene id: 29088:FAM72A
uniprot id: A0A2Y9GSK3
uniprot id: A0A2Y9GWL8
uniprot id: A0A2Y9GY56
names: Similarity
messages: Belongs to the FAM72 family.

29088:LOC110587626
gene id: 29088:LOC110587626
uniprot id: A0A8M1M613
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

29088:LOC110576532
gene id: 29088:LOC110576532
uniprot id: A0A2Y9GU54
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:GNPAT
gene id: 29088:GNPAT
uniprot id: A0A2Y9HJ31
uniprot id: A0A2Y9HJG6
uniprot id: A0A2Y9HJH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Peroxisome membrane

29088:YES1
gene id: 29088:YES1
uniprot id: A0A2Y9GWR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

29088:SLC29A4
gene id: 29088:SLC29A4
uniprot id: A0A2Y9G9S3
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

29088:RNF152
gene id: 29088:RNF152
uniprot id: A0A2Y9GR98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF152 family.
messages: Lysosome membrane
messages: Membrane

29088:LOC110575837
gene id: 29088:LOC110575837
uniprot id: A0A2Y9GTG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:FGF11
gene id: 29088:FGF11
uniprot id: A0A2Y9HEZ9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

29088:EMC3
gene id: 29088:EMC3
uniprot id: A0A2Y9HM50
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

29088:SAMD8
gene id: 29088:SAMD8
uniprot id: A0A2Y9HVV4
uniprot id: A0A2Y9HWC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

29088:PJVK
gene id: 29088:PJVK
uniprot id: A0A2Y9I5D2
names: Similarity
messages: Belongs to the gasdermin family.

29088:HOMER1
gene id: 29088:HOMER1
uniprot id: A0A2Y9HVF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

29088:VEZT
gene id: 29088:VEZT
uniprot id: A0A2Y9GZF6
uniprot id: A0A8M1M9X5
uniprot id: A0A8M1MA57
uniprot id: A0A8M1MDN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vezatin family.
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: adherens junction

29088:GPR179
gene id: 29088:GPR179
uniprot id: A0A2Y9ICU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:ITGA9
gene id: 29088:ITGA9
uniprot id: A0A2Y9G633
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

29088:LOC110588497
gene id: 29088:LOC110588497
uniprot id: A0A8M1M7Q7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

29088:CTNNAL1
gene id: 29088:CTNNAL1
uniprot id: A0A8M1MQX8
names: Similarity
messages: Belongs to the vinculin/alpha-catenin family.

29088:LONP1
gene id: 29088:LONP1
uniprot id: A0A2Y9IA40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters.
messages: Belongs to the peptidase S16 family.
messages: Homohexamer. Organized in a ring with a central cavity. The ATP-binding and proteolytic domains (AP-domain) form a hexameric chamber, while the N-terminal domain is arranged as a trimer of dimers. DNA and RNA binding is stimulated by substrate and inhibited by ATP binding. Interacts with TWNK and mitochondrial DNA polymerase subunit POLG.
messages: Mitochondrion matrix

29088:SERPINB2
gene id: 29088:SERPINB2
uniprot id: A0A2Y9GW57
names: Similarity
messages: Belongs to the serpin family.

29088:PRRT1B
gene id: 29088:PRRT1B
uniprot id: A0A2Y9H6E3
names: Similarity
messages: Belongs to the CD225/Dispanin family.

29088:MPV17L
gene id: 29088:MPV17L
uniprot id: A0A2Y9HVN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

29088:LOC123323427
gene id: 29088:LOC123323427
uniprot id: A0A2Y9HWD6
uniprot id: A0A8M1M2C9
names: Similarity
messages: Belongs to the NAC-beta family.

29088:SRC
gene id: 29088:SRC
uniprot id: A0A2Y9H031
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

29088:GART
gene id: 29088:GART
uniprot id: A0A2Y9G408
names: Similarity
messages: In the C-terminal section; belongs to the GART family.
messages: In the N-terminal section; belongs to the GARS family.
messages: In the central section; belongs to the AIR synthase family.

29088:LOC110580164
gene id: 29088:LOC110580164
uniprot id: A0A8M1MSM9
uniprot id: A0A8M1MYD7
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

29088:MIS18A
gene id: 29088:MIS18A
uniprot id: A0A2Y9G3T9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

29088:MLH3
gene id: 29088:MLH3
uniprot id: A0A2Y9G8I8
uniprot id: A0A8M1MJ75
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

29088:ACAD9
gene id: 29088:ACAD9
uniprot id: A0A2Y9HFZ2
uniprot id: A0A2Y9HGE4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

29088:PIEZO1
gene id: 29088:PIEZO1
uniprot id: A0A8M1MXA7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIEZO (TC 1.A.75) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:RPL3
gene id: 29088:RPL3
uniprot id: A0A2Y9GV67
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

29088:TMCO5A
gene id: 29088:TMCO5A
uniprot id: A0A2Y9HHY2
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110593592
gene id: 29088:LOC110593592
uniprot id: A0A2Y9IDT8
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Belongs to the calycin superfamily. Lipocalin family.

29088:LOC110573212
gene id: 29088:LOC110573212
uniprot id: A0A2Y9GE59
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.

29088:CFAP206
gene id: 29088:CFAP206
uniprot id: A0A2Y9HBQ6
uniprot id: A0A2Y9HIE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP206 family.
messages: cilium axoneme

29088:PARP3
gene id: 29088:PARP3
uniprot id: A0A2Y9HN46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

29088:DOK1
gene id: 29088:DOK1
uniprot id: A0A2Y9HZW6
uniprot id: A0A8M1MNM0
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

29088:LOC110580520
gene id: 29088:LOC110580520
uniprot id: A0A2Y9H2Q5
names: Similarity
messages: Belongs to the BEX family.

29088:LOC110585509
gene id: 29088:LOC110585509
uniprot id: A0A2Y9HHU7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ANXA5
gene id: 29088:ANXA5
uniprot id: A0A2Y9GI46
names: Domain
names: Function
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.

29088:SMUG1
gene id: 29088:SMUG1
uniprot id: A0A2Y9GT66
uniprot id: A0A8M1MAE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. SMUG1 family.
messages: Nucleus

29088:LOC110572014
gene id: 29088:LOC110572014
uniprot id: A0A2Y9GE68
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:CNOT6L
gene id: 29088:CNOT6L
uniprot id: A0A8M1M4R8
uniprot id: A0A8M1M771
uniprot id: A0A8M1MCT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

29088:TMEM135
gene id: 29088:TMEM135
uniprot id: A0A8M1MMR4
uniprot id: A0A8M1MMR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM135 family.
messages: Membrane

29088:CDK18
gene id: 29088:CDK18
uniprot id: A0A2Y9GSW5
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:PIGB
gene id: 29088:PIGB
uniprot id: A0A2Y9HD96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:HCK
gene id: 29088:HCK
uniprot id: A0A2Y9GZD3
uniprot id: A0A2Y9H5R2
uniprot id: A0A8M1MV12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

29088:ZFYVE26
gene id: 29088:ZFYVE26
uniprot id: A0A2Y9G8Z0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with AP5Z1, AP5B1, AP5S1 and SPG11. Interacts with TTC19 and KIF13A.
messages: Midbody
messages: Phosphatidylinositol 3-phosphate-binding protein required for the abcission step in cytokinesis: recruited to the midbody during cytokinesis and acts as a regulator of abcission. May also be required for efficient homologous recombination DNA double-strand break repair.

29088:AP1M2
gene id: 29088:AP1M2
uniprot id: A0A2Y9I9Y3
uniprot id: A0A2Y9IAL5
uniprot id: A0A8M1MTB2
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

29088:AEBP1
gene id: 29088:AEBP1
uniprot id: A0A8M1MTU2
names: Similarity
messages: Belongs to the peptidase M14 family.

29088:LOC110593304
gene id: 29088:LOC110593304
uniprot id: A0A8M1M5G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

29088:LOC110589322
gene id: 29088:LOC110589322
uniprot id: A0A2Y9HVG1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

29088:GPR18
gene id: 29088:GPR18
uniprot id: A0A2Y9HJ10
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:KPNA7
gene id: 29088:KPNA7
uniprot id: A0A2Y9G9Q9
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

29088:PRPF38B
gene id: 29088:PRPF38B
uniprot id: A0A2Y9H8N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: May be required for pre-mRNA splicing.
messages: Nucleus

29088:CCDC181
gene id: 29088:CCDC181
uniprot id: A0A2Y9GGS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC181 family.
messages: Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids.
messages: cytoskeleton
messages: flagellum

29088:SRPX2
gene id: 29088:SRPX2
uniprot id: A0A2Y9HMH9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110586961
gene id: 29088:LOC110586961
uniprot id: A0A8M1MKK1
names: Subcellular Location Annotation
messages: Nucleus

29088:CEBPG
gene id: 29088:CEBPG
uniprot id: A0A8M1MXE6
names: Similarity
messages: Belongs to the bZIP family. C/EBP subfamily.

29088:PPARGC1B
gene id: 29088:PPARGC1B
uniprot id: A0A2Y9HHB9
uniprot id: A0A8M1MQ13
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110593819
gene id: 29088:LOC110593819
uniprot id: A0A2Y9IAY5
names: Similarity
messages: Belongs to the peptidase S14 family.

29088:SLC37A1
gene id: 29088:SLC37A1
uniprot id: A0A2Y9GAM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucose levels.
messages: Membrane

29088:MDGA2
gene id: 29088:MDGA2
uniprot id: A0A2Y9HZI2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:APPL2
gene id: 29088:APPL2
uniprot id: A0A2Y9GUS1
uniprot id: A0A2Y9GUX6
uniprot id: A0A8M1MDY9
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: Nucleus
messages: phagosome
messages: ruffle

29088:LOC123324338
gene id: 29088:LOC123324338
uniprot id: A0A8M1MAM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

29088:INSL6
gene id: 29088:INSL6
uniprot id: A0A2Y9HEE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

29088:LHX9
gene id: 29088:LHX9
uniprot id: A0A2Y9GGB7
uniprot id: A0A2Y9GGE2
uniprot id: A0A8M1MI40
names: Subcellular Location Annotation
messages: Nucleus

29088:HTRA1
gene id: 29088:HTRA1
uniprot id: A0A2Y9IB17
names: Similarity
messages: Belongs to the peptidase S1C family.

29088:MAN2C1
gene id: 29088:MAN2C1
uniprot id: A0A2Y9HCQ1
uniprot id: A0A2Y9HII6
uniprot id: A0A2Y9HJ03
uniprot id: A0A8M1MKM9
uniprot id: A0A8M1MMN9
uniprot id: A0A8M1MNZ6
uniprot id: A0A8M1MUS2
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

29088:TERF2
gene id: 29088:TERF2
uniprot id: A0A2Y9I4S9
names: Subcellular Location Annotation
messages: telomere

29088:TNKS
gene id: 29088:TNKS
uniprot id: A0A2Y9HDS6
names: Function
names: Similarity
messages: Belongs to the ARTD/PARP family.
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

29088:CD3E
gene id: 29088:CD3E
uniprot id: A0A2Y9HK47
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:PPP6R3
gene id: 29088:PPP6R3
uniprot id: A0A2Y9GPP4
uniprot id: A0A2Y9GPX2
uniprot id: A0A2Y9GQ13
uniprot id: A0A2Y9GTR7
uniprot id: A0A8M1MNH9
uniprot id: A0A8M1MRS3
uniprot id: A0A8M1MXF1
names: Similarity
messages: Belongs to the SAPS family.

29088:LOC110573940
gene id: 29088:LOC110573940
uniprot id: A0A8M1MNE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

29088:THOC6
gene id: 29088:THOC6
uniprot id: A0A2Y9HVV5
uniprot id: A0A8M1MD61
names: Similarity
messages: Belongs to the WD repeat THOC6 family.

29088:PTK7
gene id: 29088:PTK7
uniprot id: A0A2Y9H7Z0
names: Subcellular Location Annotation
messages: Membrane

29088:CASP7
gene id: 29088:CASP7
uniprot id: A0A2Y9HV05
uniprot id: A0A2Y9I1C8
uniprot id: A0A8M1MFA9
names: Similarity
messages: Belongs to the peptidase C14A family.

29088:EOMES
gene id: 29088:EOMES
uniprot id: A0A2Y9G650
uniprot id: A0A2Y9G653
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

29088:ARPC5L
gene id: 29088:ARPC5L
uniprot id: A0A2Y9H724
uniprot id: A0A8M1MSD8
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

29088:ZDHHC19
gene id: 29088:ZDHHC19
uniprot id: A0A8M1MTQ9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

29088:IL11RA
gene id: 29088:IL11RA
uniprot id: A0A2Y9H5E4
uniprot id: A0A2Y9HAS0
uniprot id: A0A8M1MYF9
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 3 subfamily.

29088:LOC110578480
gene id: 29088:LOC110578480
uniprot id: A0A8M1M920
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

29088:IP6K2
gene id: 29088:IP6K2
uniprot id: A0A2Y9GTN5
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

29088:MPDZ
gene id: 29088:MPDZ
uniprot id: A0A2Y9GJC6
names: Subcellular Location Annotation
messages: Cell membrane
messages: tight junction

29088:STARD3NL
gene id: 29088:STARD3NL
uniprot id: A0A2Y9GKU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Membrane

29088:TEX10
gene id: 29088:TEX10
uniprot id: A0A2Y9H576
names: Similarity
messages: Belongs to the IPI1/TEX10 family.

29088:TOP3A
gene id: 29088:TOP3A
uniprot id: A0A2Y9HEV5
uniprot id: A0A8M1MZ33
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

29088:CFTR
gene id: 29088:CFTR
uniprot id: A0A2Y9HTW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
messages: Membrane
messages: Monomer; does not require oligomerization for channel activity. May form oligomers in the membrane (By similarity). Interacts with SLC26A3, SLC26A6 and NHERF1 (By similarity). Interacts with SHANK2 (By similarity). Interacts with MYO6 (By similarity). Interacts (via C-terminus) with GOPC (via PDZ domain); this promotes CFTR internalization and thereby decreases channel activity. Interacts with SLC4A7 through NHERF1. Found in a complex with MYO5B and RAB11A. Interacts with ANO1. Interacts with SLC26A8 (By similarity). Interacts with AHCYL1; the interaction increases CFTR activity (By similarity). Interacts with CSE1L (By similarity). The core-glycosylated form interacts with GORASP2 (via PDZ GRASP-type 1 domain) in respone to ER stress (By similarity). Interacts with MARCHF2; the interaction leads to CFTR ubiqtuitination and degradation.
messages: Recycling endosome membrane

29088:OGDH
gene id: 29088:OGDH
uniprot id: A0A2Y9IDG8
uniprot id: A0A8M1MPY9
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

29088:HEXB
gene id: 29088:HEXB
uniprot id: A0A2Y9I629
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

29088:LOC110571842
gene id: 29088:LOC110571842
uniprot id: A0A2Y9G9I7
uniprot id: A0A2Y9G9Q7
uniprot id: A0A8M1M9K3
uniprot id: A0A8M1MD30
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

29088:DCPS
gene id: 29088:DCPS
uniprot id: A0A2Y9HRN4
uniprot id: A0A8M1MND7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HIT family.
messages: Cytoplasm
messages: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway.
messages: Homodimer. Associates with components of the exosome multienzyme ribonuclease complex, such as EXOSC3 and EXOSC4. Interacts with NDOR1.
messages: Nucleus

29088:LOC110594174
gene id: 29088:LOC110594174
uniprot id: A0A2Y9IBE8
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Homotetramer.

29088:MAPK6
gene id: 29088:MAPK6
uniprot id: A0A2Y9HIR2
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

29088:AVPI1
gene id: 29088:AVPI1
uniprot id: A0A2Y9HU10
uniprot id: A0A8M1MDW9
names: Function
messages: May be involved in MAP kinase activation, epithelial sodium channel (ENaC) down-regulation and cell cycling.

29088:EVC
gene id: 29088:EVC
uniprot id: A0A2Y9G6D5
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

29088:LOC110574955
gene id: 29088:LOC110574955
uniprot id: A0A2Y9GQ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVBP family.
messages: Secreted
messages: cytoskeleton

29088:BARX1
gene id: 29088:BARX1
uniprot id: A0A2Y9HEQ5
names: Subcellular Location Annotation
messages: Nucleus

29088:SMARCA1
gene id: 29088:SMARCA1
uniprot id: A0A2Y9GQH4
uniprot id: A0A2Y9GQM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

29088:TNXB
gene id: 29088:TNXB
uniprot id: A0A8M1MH48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: extracellular matrix

29088:SEH1L
gene id: 29088:SEH1L
uniprot id: A0A2Y9GHR2
uniprot id: A0A2Y9GMX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore.
messages: Lysosome membrane
messages: kinetochore

29088:LOC110579682
gene id: 29088:LOC110579682
uniprot id: A0A2Y9H4X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GnRH family.
messages: Secreted
messages: Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.

29088:LRRC51
gene id: 29088:LRRC51
uniprot id: A0A8M1MS80
uniprot id: A0A8M1MXP8
names: Subcellular Location Annotation
messages: Cytoplasm

29088:TAFAZZIN
gene id: 29088:TAFAZZIN
uniprot id: A0A2Y9GHE6
uniprot id: A0A2Y9GHG1
uniprot id: A0A2Y9GHI2
uniprot id: A0A2Y9GHJ0
uniprot id: A0A2Y9GKQ2
uniprot id: A0A2Y9GKR4
uniprot id: A0A2Y9GMJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acyltransferase which is required to remodel newly synthesized phospholipid cardiolipin, a key component of the mitochondrial inner membrane. Required for the initiation of mitophagy. Required to ensure progression of spermatocytes through meiosis.
messages: Associates with multiple protein complexes.
messages: Belongs to the taffazin family.
messages: Mitochondrion inner membrane
messages: Mitochondrion outer membrane

29088:TANGO6
gene id: 29088:TANGO6
uniprot id: A0A2Y9IBB4
names: Similarity
messages: Belongs to the Tango6 family.

29088:LOC110572327
gene id: 29088:LOC110572327
uniprot id: A0A2Y9GB59
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

29088:LOC110590129
gene id: 29088:LOC110590129
uniprot id: A0A2Y9HY95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:SULT1C2
gene id: 29088:SULT1C2
uniprot id: A0A2Y9GD02
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

29088:LOC110576171
gene id: 29088:LOC110576171
uniprot id: A0A2Y9GUJ2
names: Similarity
messages: Belongs to the MS4A family.

29088:CTSF
gene id: 29088:CTSF
uniprot id: A0A8M1MR04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

29088:NKIRAS2
gene id: 29088:NKIRAS2
uniprot id: A0A2Y9GHA7
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

29088:ARPC4
gene id: 29088:ARPC4
uniprot id: A0A2Y9HGM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Cell projection
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: cytoskeleton

29088:LOC110576486
gene id: 29088:LOC110576486
uniprot id: A0A2Y9GU07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:CMAS
gene id: 29088:CMAS
uniprot id: A0A2Y9H3E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN).
messages: Homotetramer; the active enzyme is formed by a dimer of dimers.

29088:LOC110577597
gene id: 29088:LOC110577597
uniprot id: A0A8M1MZ81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SCAP family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

29088:LOC110571721
gene id: 29088:LOC110571721
uniprot id: A0A2Y9G9F6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:PLXNA1
gene id: 29088:PLXNA1
uniprot id: A0A2Y9HG37
uniprot id: A0A8M1MSI4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:MCTP2
gene id: 29088:MCTP2
uniprot id: A0A2Y9GBB9
uniprot id: A0A2Y9GE48
uniprot id: A0A2Y9GFN6
names: Subcellular Location Annotation
messages: Membrane

29088:CEP44
gene id: 29088:CEP44
uniprot id: A0A2Y9HS15
uniprot id: A0A2Y9HS22
uniprot id: A0A2Y9HWY4
names: Subcellular Location Annotation
messages: Midbody
messages: centriole
messages: spindle pole

29088:HFE
gene id: 29088:HFE
uniprot id: A0A2Y9HLE3
uniprot id: A0A2Y9HRW9
uniprot id: A0A2Y9HSZ9
uniprot id: A0A8M1MI47
uniprot id: A0A8M1MK68
names: Similarity
messages: Belongs to the MHC class I family.

29088:AMPD2
gene id: 29088:AMPD2
uniprot id: A0A2Y9H2T5
uniprot id: A0A2Y9H2V1
uniprot id: A0A2Y9H2W7
uniprot id: A0A2Y9H7V2
uniprot id: A0A8M1MBW1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

29088:LOC110576110
gene id: 29088:LOC110576110
uniprot id: A0A2Y9GNR5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110570003
gene id: 29088:LOC110570003
uniprot id: A0A2Y9G469
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Monomer.

29088:DNASE1L2
gene id: 29088:DNASE1L2
uniprot id: A0A2Y9HWX9
names: Similarity
messages: Belongs to the DNase I family.

29088:TMEM19
gene id: 29088:TMEM19
uniprot id: A0A2Y9G841
uniprot id: A0A2Y9G986
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

29088:LOC110593846
gene id: 29088:LOC110593846
uniprot id: A0A8M1MXA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

29088:NANOS2
gene id: 29088:NANOS2
uniprot id: A0A2Y9GCW6
names: Similarity
messages: Belongs to the nanos family.

29088:SULT4A1
gene id: 29088:SULT4A1
uniprot id: A0A8M1MLI8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

29088:HSD17B13
gene id: 29088:HSD17B13
uniprot id: A0A2Y9I6U8
uniprot id: A0A2Y9I8X8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29088:HEBP1
gene id: 29088:HEBP1
uniprot id: A0A2Y9HAF4
names: Similarity
messages: Belongs to the HEBP family.

29088:CAT
gene id: 29088:CAT
uniprot id: A0A2Y9GUU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Peroxisome

29088:LOC110570935
gene id: 29088:LOC110570935
uniprot id: A0A2Y9G720
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:SLC28A1
gene id: 29088:SLC28A1
uniprot id: A0A8M1MLC9
uniprot id: A0A8M1MTC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

29088:NCK2
gene id: 29088:NCK2
uniprot id: A0A2Y9GAJ7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

29088:LOC110580309
gene id: 29088:LOC110580309
uniprot id: A0A8M1MBT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGP family.
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

29088:KDM1B
gene id: 29088:KDM1B
uniprot id: A0A2Y9HS24
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

29088:NOL11
gene id: 29088:NOL11
uniprot id: A0A2Y9G8K4
names: Subcellular Location Annotation
messages: nucleolus

29088:FZD5
gene id: 29088:FZD5
uniprot id: A0A2Y9IBV4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:SLC6A1
gene id: 29088:SLC6A1
uniprot id: A0A2Y9HMA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

29088:CEPT1
gene id: 29088:CEPT1
uniprot id: A0A2Y9H7K3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

29088:SENP2
gene id: 29088:SENP2
uniprot id: A0A2Y9HFH3
uniprot id: A0A2Y9HGB9
names: Similarity
messages: Belongs to the peptidase C48 family.

29088:DNA2
gene id: 29088:DNA2
uniprot id: A0A2Y9HVE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.
messages: Mitochondrion
messages: Nucleus

29088:C4H8orf33
gene id: 29088:C4H8orf33
uniprot id: A0A2Y9GYE4
uniprot id: A0A2Y9H4P3
names: Similarity
messages: Belongs to the UPF0488 family.

29088:CEP162
gene id: 29088:CEP162
uniprot id: A0A2Y9HB98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP162 family.
messages: centriole

29088:MPZ
gene id: 29088:MPZ
uniprot id: A0A2Y9GHU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the myelin P0 protein family.
messages: Cell membrane
messages: Homodimer and homotetramer.
messages: Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction.
messages: Membrane

29088:PYGL
gene id: 29088:PYGL
uniprot id: A0A2Y9HZ81
uniprot id: A0A2Y9HZF1
uniprot id: A0A8M1MJ50
uniprot id: A0A8M1MMH3
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

29088:LOC110577103
gene id: 29088:LOC110577103
uniprot id: A0A8M1M8Z2
names: Similarity
messages: Belongs to the intermediate filament family.

29088:NANOS3
gene id: 29088:NANOS3
uniprot id: A0A2Y9IB04
names: Similarity
messages: Belongs to the nanos family.

29088:LOC110575869
gene id: 29088:LOC110575869
uniprot id: A0A2Y9GRW0
names: Similarity
messages: Belongs to the MS4A family.

29088:MYOZ1
gene id: 29088:MYOZ1
uniprot id: A0A8M1MH49
names: Similarity
messages: Belongs to the myozenin family.

29088:SIGIRR
gene id: 29088:SIGIRR
uniprot id: A0A2Y9H859
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

29088:GPBP1L1
gene id: 29088:GPBP1L1
uniprot id: A0A2Y9GL44
uniprot id: A0A2Y9GL88
uniprot id: A0A8M1M9H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

29088:AJAP1
gene id: 29088:AJAP1
uniprot id: A0A8M1MFK5
names: Subcellular Location Annotation
messages: Membrane

29088:CCDC124
gene id: 29088:CCDC124
uniprot id: A0A2Y9GLF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC124 family.
messages: Midbody

29088:KPNA2
gene id: 29088:KPNA2
uniprot id: A0A2Y9G4Z0
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

29088:LOC110591860
gene id: 29088:LOC110591860
uniprot id: A0A8M1M731
names: Similarity
messages: Belongs to the NAC-beta family.

29088:C7H5orf22
gene id: 29088:C7H5orf22
uniprot id: A0A2Y9HQ91
names: Similarity
messages: Belongs to the UPF0489 family.

29088:EML1
gene id: 29088:EML1
uniprot id: A0A8M1MNN2
uniprot id: A0A8M1MUE8
names: Similarity
messages: Belongs to the WD repeat EMAP family.

29088:BTC
gene id: 29088:BTC
uniprot id: A0A2Y9I2N2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:VAPB
gene id: 29088:VAPB
uniprot id: A0A2Y9G6Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:PIP4P2
gene id: 29088:PIP4P2
uniprot id: A0A2Y9H3Q5
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: phagosome membrane

29088:CD53
gene id: 29088:CD53
uniprot id: A0A2Y9H914
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

29088:SLC8B1
gene id: 29088:SLC8B1
uniprot id: A0A2Y9HR34
uniprot id: A0A2Y9HWC1
uniprot id: A0A8M1MYS0
names: Subcellular Location Annotation
messages: Membrane

29088:LIN28A
gene id: 29088:LIN28A
uniprot id: A0A2Y9GJB9
names: Similarity
messages: Belongs to the lin-28 family.

29088:LOC110590332
gene id: 29088:LOC110590332
uniprot id: A0A2Y9I3I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Membrane
messages: Microsome membrane

29088:PRKAR1B
gene id: 29088:PRKAR1B
uniprot id: A0A2Y9GA06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

29088:MTX1
gene id: 29088:MTX1
uniprot id: A0A8M1MH65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

29088:MOSPD1
gene id: 29088:MOSPD1
uniprot id: A0A2Y9GQD6
names: Subcellular Location Annotation
messages: Membrane

29088:PTPRA
gene id: 29088:PTPRA
uniprot id: A0A2Y9GZV8
uniprot id: A0A2Y9GZW8
uniprot id: A0A2Y9H6A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.
messages: Cell membrane
messages: Membrane

29088:DDX50
gene id: 29088:DDX50
uniprot id: A0A2Y9HTQ0
uniprot id: A0A2Y9HU87
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.

29088:PAN3
gene id: 29088:PAN3
uniprot id: A0A2Y9G4Q1
uniprot id: A0A2Y9G4S1
uniprot id: A0A2Y9G8B8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PABPC1 (via PABC domain), conferring substrate specificity of the enzyme complex. Interacts with the GW182 family proteins TNRC6A, TNRC6B and TNRC6C.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: P-body
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and PABP, and to miRNA targets via its interaction with GW182 family proteins.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

29088:SMO
gene id: 29088:SMO
uniprot id: A0A2Y9HYQ2
uniprot id: A0A2Y9I091
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: cilium

29088:PHF20
gene id: 29088:PHF20
uniprot id: A0A2Y9H444
names: Subcellular Location Annotation
messages: Nucleus

29088:NUP50
gene id: 29088:NUP50
uniprot id: A0A2Y9GVY3
uniprot id: A0A2Y9H0B4
names: Subcellular Location Annotation
messages: nuclear pore complex

29088:CPPED1
gene id: 29088:CPPED1
uniprot id: A0A2Y9HWU8
names: Function
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. CPPED1 family.
messages: Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.

29088:LOC110581759
gene id: 29088:LOC110581759
uniprot id: A0A8M1MRV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

29088:ELP3
gene id: 29088:ELP3
uniprot id: A0A2Y9HSA7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

29088:RAD23A
gene id: 29088:RAD23A
uniprot id: A0A2Y9I9P9
uniprot id: A0A2Y9IAD5
uniprot id: A0A8M1MIT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

29088:ANXA2
gene id: 29088:ANXA2
uniprot id: A0A2Y9HCI5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9.
messages: Membrane
messages: basement membrane

29088:RSAD1
gene id: 29088:RSAD1
uniprot id: A0A2Y9ICE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen-III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Mitochondrion

29088:NOL8
gene id: 29088:NOL8
uniprot id: A0A2Y9HED5
names: Subcellular Location Annotation
messages: nucleolus

29088:LOC110573684
gene id: 29088:LOC110573684
uniprot id: A0A8M1MVS1
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

29088:NPFFR1
gene id: 29088:NPFFR1
uniprot id: A0A2Y9HV35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

29088:NEMF
gene id: 29088:NEMF
uniprot id: A0A8M1MJW0
uniprot id: A0A8M1MN83
names: Similarity
messages: Belongs to the NEMF family.

29088:LOC110589844
gene id: 29088:LOC110589844
uniprot id: A0A2Y9HX09
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

29088:FLCN
gene id: 29088:FLCN
uniprot id: A0A2Y9HER9
uniprot id: A0A2Y9HL16
uniprot id: A0A2Y9HL21
uniprot id: A0A2Y9HL62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the folliculin family.
messages: Lysosome membrane
messages: Membrane
messages: Nucleus
messages: centrosome
messages: cilium
messages: cytosol
messages: spindle

29088:LOC110577149
gene id: 29088:LOC110577149
uniprot id: A0A8M1MYX1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

29088:XPO5
gene id: 29088:XPO5
uniprot id: A0A8M1MKL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm

29088:AMER2
gene id: 29088:AMER2
uniprot id: A0A2Y9G4D2
uniprot id: A0A2Y9G6Y1
names: Similarity
messages: Belongs to the Amer family.

29088:LOC110573324
gene id: 29088:LOC110573324
uniprot id: A0A2Y9GEI7
uniprot id: A0A8M1MUW5
uniprot id: A0A8M1MXH0
names: Similarity
messages: Belongs to the intermediate filament family.

29088:GLDC
gene id: 29088:GLDC
uniprot id: A0A2Y9GL02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

29088:MRS2
gene id: 29088:MRS2
uniprot id: A0A2Y9HSA5
uniprot id: A0A8M1MHL4
uniprot id: A0A8M1MKZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane

29088:TMEM17
gene id: 29088:TMEM17
uniprot id: A0A2Y9HSZ7
names: Subcellular Location Annotation
messages: Membrane

29088:ADD1
gene id: 29088:ADD1
uniprot id: A0A8M1M532
uniprot id: A0A8M1M7H4
uniprot id: A0A8M1M8Z0
uniprot id: A0A8M1MD59
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

29088:TMEM192
gene id: 29088:TMEM192
uniprot id: A0A2Y9HX98
uniprot id: A0A2Y9HYU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM192 family.
messages: Late endosome
messages: Lysosome membrane
messages: Membrane

29088:KCNK16
gene id: 29088:KCNK16
uniprot id: A0A2Y9GM83
uniprot id: A0A2Y9GME2
uniprot id: A0A2Y9GR26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

29088:ACSS3
gene id: 29088:ACSS3
uniprot id: A0A2Y9H1S0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

29088:CSAD
gene id: 29088:CSAD
uniprot id: A0A2Y9GX00
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

29088:TIPIN
gene id: 29088:TIPIN
uniprot id: A0A2Y9HD09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSM3 family.
messages: Nucleus
messages: Plays an important role in the control of DNA replication and the maintenance of replication fork stability.

29088:LOXL2
gene id: 29088:LOXL2
uniprot id: A0A2Y9HS67
uniprot id: A0A8M1M7N6
uniprot id: A0A8M1MBN7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

29088:NGF
gene id: 29088:NGF
uniprot id: A0A2Y9H2Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted

29088:LOC110589872
gene id: 29088:LOC110589872
uniprot id: A0A2Y9HX36
uniprot id: A0A2Y9I200
uniprot id: A0A8M1MCP5
uniprot id: A0A8M1MCU5
uniprot id: A0A8M1MGB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
messages: Nucleus

29088:TNS3
gene id: 29088:TNS3
uniprot id: A0A2Y9I5Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

29088:P2RY13
gene id: 29088:P2RY13
uniprot id: A0A2Y9GQR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:POLR1E
gene id: 29088:POLR1E
uniprot id: A0A2Y9H5N1
uniprot id: A0A2Y9HCC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
messages: nucleolus

29088:EAF1
gene id: 29088:EAF1
uniprot id: A0A2Y9G9W7
names: Similarity
messages: Belongs to the EAF family.

29088:LOC110572922
gene id: 29088:LOC110572922
uniprot id: A0A2Y9GG94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LicD transferase family.
messages: Golgi apparatus membrane

29088:CPNE5
gene id: 29088:CPNE5
uniprot id: A0A2Y9GSQ4
uniprot id: A0A8M1MHP8
names: Similarity
messages: Belongs to the copine family.

29088:CITED2
gene id: 29088:CITED2
uniprot id: A0A2Y9HB52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

29088:HPS6
gene id: 29088:HPS6
uniprot id: A0A2Y9I0F0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6. Interacts with HPS5 and HPS3. Interacts with biogenesis of lysosome-related organelles complex-1 (BLOC1). Interacts with AP-3 complex.
messages: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
messages: Microsome membrane

29088:PSMD7
gene id: 29088:PSMD7
uniprot id: A0A2Y9I4P6
names: Similarity
messages: Belongs to the peptidase M67A family.

29088:ODC1
gene id: 29088:ODC1
uniprot id: A0A2Y9HPH5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

29088:CDSN
gene id: 29088:CDSN
uniprot id: A0A2Y9HLU1
names: Function
names: Subcellular Location Annotation
messages: Important for the epidermal barrier integrity.
messages: Secreted

29088:LOC110575662
gene id: 29088:LOC110575662
uniprot id: A0A2Y9GMB1
uniprot id: A0A8M1MLR8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

29088:MYMK
gene id: 29088:MYMK
uniprot id: A0A2Y9H6R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

29088:MDH1B
gene id: 29088:MDH1B
uniprot id: A0A2Y9I4K3
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

29088:SKAP1
gene id: 29088:SKAP1
uniprot id: A0A2Y9IF21
names: Similarity
messages: Belongs to the SKAP family.

29088:C14H18orf21
gene id: 29088:C14H18orf21
uniprot id: A0A2Y9GRR9
uniprot id: A0A2Y9GXH0
names: Similarity
messages: Belongs to the UPF0711 family.

29088:PDLIM3
gene id: 29088:PDLIM3
uniprot id: A0A2Y9HJN4
uniprot id: A0A2Y9HK13
names: Subcellular Location Annotation
messages: Z line

29088:SPSB1
gene id: 29088:SPSB1
uniprot id: A0A2Y9GJ49
names: Similarity
messages: Belongs to the SPSB family.

29088:LOC110593419
gene id: 29088:LOC110593419
uniprot id: A0A8M1MPD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

29088:SLC10A2
gene id: 29088:SLC10A2
uniprot id: A0A2Y9HJ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

29088:LOC110570615
gene id: 29088:LOC110570615
uniprot id: A0A2Y9G5Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GST superfamily. Pi family.
messages: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
messages: Cytoplasm
messages: Homodimer.
messages: Mitochondrion
messages: Nucleus

29088:TRPM8
gene id: 29088:TRPM8
uniprot id: A0A2Y9GA16
names: Subcellular Location Annotation
messages: Membrane

29088:CAPN12
gene id: 29088:CAPN12
uniprot id: A0A2Y9HZ03
names: Similarity
messages: Belongs to the peptidase C2 family.

29088:TNFRSF21
gene id: 29088:TNFRSF21
uniprot id: A0A2Y9HEK4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110575808
gene id: 29088:LOC110575808
uniprot id: A0A2Y9GTE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110593257
gene id: 29088:LOC110593257
uniprot id: A0A8M1MVA0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.