290317:CPHA266 RS02010
gene id: 290317:CPHA266_RS02010
uniprot id: A1BDH2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

290317:CPHA266 RS00620
gene id: 290317:CPHA266_RS00620
uniprot id: A1BCR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

290317:CPHA266 RS02310
gene id: 290317:CPHA266_RS02310
uniprot id: A1BDM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

290317:CPHA266 RS01900
gene id: 290317:CPHA266_RS01900
uniprot id: A1BDF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

290317:CPHA266 RS10830
gene id: 290317:CPHA266_RS10830
uniprot id: A1BI67
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

290317:CPHA266 RS10050
gene id: 290317:CPHA266_RS10050
uniprot id: A1BHS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

290317:CPHA266 RS05185
gene id: 290317:CPHA266_RS05185
uniprot id: A1BF68
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

290317:CPHA266 RS05860
gene id: 290317:CPHA266_RS05860
uniprot id: A1BCG8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

290317:CPHA266 RS01155
gene id: 290317:CPHA266_RS01155
uniprot id: A1BD15
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

290317:CPHA266 RS05025
gene id: 290317:CPHA266_RS05025
uniprot id: A1BF35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

290317:CPHA266 RS13980
gene id: 290317:CPHA266_RS13980
uniprot id: A1BJV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

290317:CPHA266 RS01740
gene id: 290317:CPHA266_RS01740
uniprot id: A1BDC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

290317:CPHA266 RS09545
gene id: 290317:CPHA266_RS09545
uniprot id: A1BHI2
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS12435
gene id: 290317:CPHA266_RS12435
uniprot id: A1BJ13
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

290317:CPHA266 RS01220
gene id: 290317:CPHA266_RS01220
uniprot id: A1BD24
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

290317:CPHA266 RS01760
gene id: 290317:CPHA266_RS01760
uniprot id: A1BDC5
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

290317:CPHA266 RS14065
gene id: 290317:CPHA266_RS14065
uniprot id: A1BJW9
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

290317:CPHA266 RS12965
gene id: 290317:CPHA266_RS12965
uniprot id: A1BJB4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

290317:CPHA266 RS09670
gene id: 290317:CPHA266_RS09670
uniprot id: A1BHK7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

290317:CPHA266 RS02080
gene id: 290317:CPHA266_RS02080
uniprot id: A1BDI1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

290317:CPHA266 RS02510
gene id: 290317:CPHA266_RS02510
uniprot id: A1BDR1
names: Similarity
messages: Belongs to the ferrochelatase family.

290317:CPHA266 RS06520
gene id: 290317:CPHA266_RS06520
uniprot id: A1BFX2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

290317:CPHA266 RS01190
gene id: 290317:CPHA266_RS01190
uniprot id: A1BD18
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

290317:CPHA266 RS00015
gene id: 290317:CPHA266_RS00015
uniprot id: A1BCH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

290317:CPHA266 RS01950
gene id: 290317:CPHA266_RS01950
uniprot id: A1BDG1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

290317:CPHA266 RS12930
gene id: 290317:CPHA266_RS12930
uniprot id: A1BJA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

290317:CPHA266 RS09890
gene id: 290317:CPHA266_RS09890
uniprot id: A1BHP7
names: Function
names: Similarity
messages: A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-CTCGAG-3' and cleaves after C-1.
messages: Belongs to the XhoI type II restriction endonuclease family.

290317:CPHA266 RS06295
gene id: 290317:CPHA266_RS06295
uniprot id: A1BFS5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

290317:CPHA266 RS06930
gene id: 290317:CPHA266_RS06930
uniprot id: A1BCG8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

290317:CPHA266 RS08580
gene id: 290317:CPHA266_RS08580
uniprot id: A1BGZ9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

290317:CPHA266 RS12945
gene id: 290317:CPHA266_RS12945
uniprot id: A1BJB0
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

290317:CPHA266 RS04720
gene id: 290317:CPHA266_RS04720
uniprot id: A1BEY2
names: Similarity
messages: Belongs to the ArsC family.

290317:CPHA266 RS12400
gene id: 290317:CPHA266_RS12400
uniprot id: A1BJ05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

290317:CPHA266 RS02885
gene id: 290317:CPHA266_RS02885
uniprot id: A1BDY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

290317:CPHA266 RS04455
gene id: 290317:CPHA266_RS04455
uniprot id: A1BET1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

290317:CPHA266 RS09350
gene id: 290317:CPHA266_RS09350
uniprot id: A1BHE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

290317:CPHA266 RS01240
gene id: 290317:CPHA266_RS01240
uniprot id: A1BD28
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

290317:CPHA266 RS01605
gene id: 290317:CPHA266_RS01605
uniprot id: A1BD97
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

290317:CPHA266 RS03000
gene id: 290317:CPHA266_RS03000
uniprot id: A1BE06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

290317:CPHA266 RS05275
gene id: 290317:CPHA266_RS05275
uniprot id: A1BF85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

290317:CPHA266 RS02005
gene id: 290317:CPHA266_RS02005
uniprot id: A1BDH1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

290317:CPHA266 RS05115
gene id: 290317:CPHA266_RS05115
uniprot id: A1BF53
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

290317:CPHA266 RS07540
gene id: 290317:CPHA266_RS07540
uniprot id: A1BGG4
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

290317:CPHA266 RS06135
gene id: 290317:CPHA266_RS06135
uniprot id: A1BFP5
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

290317:CPHA266 RS02910
gene id: 290317:CPHA266_RS02910
uniprot id: A1BDY8
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

290317:CPHA266 RS03985
gene id: 290317:CPHA266_RS03985
uniprot id: A1BEJ2
names: Similarity
messages: Belongs to the HepT RNase toxin family.

290317:CPHA266 RS10555
gene id: 290317:CPHA266_RS10555
uniprot id: A1BI19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

290317:CPHA266 RS05550
gene id: 290317:CPHA266_RS05550
uniprot id: A1BFD7
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

290317:CPHA266 RS08905
gene id: 290317:CPHA266_RS08905
uniprot id: A1BH62
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS09145
gene id: 290317:CPHA266_RS09145
uniprot id: A1BHA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusB family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

290317:CPHA266 RS03045
gene id: 290317:CPHA266_RS03045
uniprot id: A1BE15
names: Similarity
messages: Belongs to the CutA family.

290317:CPHA266 RS06400
gene id: 290317:CPHA266_RS06400
uniprot id: A1BFU8
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS12465
gene id: 290317:CPHA266_RS12465
uniprot id: A1BJ19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

290317:CPHA266 RS08565
gene id: 290317:CPHA266_RS08565
uniprot id: A1BGZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

290317:CPHA266 RS09345
gene id: 290317:CPHA266_RS09345
uniprot id: A1BHE7
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS08155
gene id: 290317:CPHA266_RS08155
uniprot id: A1BGS5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane

290317:CPHA266 RS06440
gene id: 290317:CPHA266_RS06440
uniprot id: A1BFV7
names: Similarity
messages: Belongs to the DEAD box helicase family.

290317:CPHA266 RS06815
gene id: 290317:CPHA266_RS06815
uniprot id: A1BG29
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

290317:CPHA266 RS06850
gene id: 290317:CPHA266_RS06850
uniprot id: A1BG36
names: Similarity
messages: Belongs to the LacAB/RpiB family.

290317:CPHA266 RS08570
gene id: 290317:CPHA266_RS08570
uniprot id: A1BGZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell inner membrane

290317:CPHA266 RS08670
gene id: 290317:CPHA266_RS08670
uniprot id: A1BH17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

290317:CPHA266 RS09720
gene id: 290317:CPHA266_RS09720
uniprot id: A1BHL7
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

290317:CPHA266 RS10335
gene id: 290317:CPHA266_RS10335
uniprot id: A1BHX5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

290317:CPHA266 RS05045
gene id: 290317:CPHA266_RS05045
uniprot id: A1BF39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

290317:CPHA266 RS00040
gene id: 290317:CPHA266_RS00040
uniprot id: A1BCG8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

290317:CPHA266 RS00575
gene id: 290317:CPHA266_RS00575
uniprot id: A1BCQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

290317:CPHA266 RS10515
gene id: 290317:CPHA266_RS10515
uniprot id: A1BI11
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS00175
gene id: 290317:CPHA266_RS00175
uniprot id: A1BCI0
names: Similarity
messages: Belongs to the UPF0102 family.

290317:CPHA266 RS02160
gene id: 290317:CPHA266_RS02160
uniprot id: A1BDJ7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

290317:CPHA266 RS09410
gene id: 290317:CPHA266_RS09410
uniprot id: A1BHF9
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS05790
gene id: 290317:CPHA266_RS05790
uniprot id: A1BFI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

290317:CPHA266 RS03860
gene id: 290317:CPHA266_RS03860
uniprot id: A1BEG8
names: Similarity
messages: Belongs to the P(II) protein family.

290317:CPHA266 RS10900
gene id: 290317:CPHA266_RS10900
uniprot id: A1BI80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

290317:CPHA266 RS13885
gene id: 290317:CPHA266_RS13885
uniprot id: A1BJT5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

290317:CPHA266 RS06425
gene id: 290317:CPHA266_RS06425
uniprot id: A1BFV4
names: Similarity
messages: Belongs to the arsA ATPase family.

290317:CPHA266 RS03735
gene id: 290317:CPHA266_RS03735
uniprot id: A1BEE4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

290317:CPHA266 RS13250
gene id: 290317:CPHA266_RS13250
uniprot id: A1BJG7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

290317:CPHA266 RS08555
gene id: 290317:CPHA266_RS08555
uniprot id: A1BGZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

290317:CPHA266 RS03680
gene id: 290317:CPHA266_RS03680
uniprot id: A1BED5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

290317:CPHA266 RS09460
gene id: 290317:CPHA266_RS09460
uniprot id: A1BHG9
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

290317:CPHA266 RS04140
gene id: 290317:CPHA266_RS04140
uniprot id: A1BEM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

290317:CPHA266 RS07950
gene id: 290317:CPHA266_RS07950
uniprot id: A1BGN8
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS07845
gene id: 290317:CPHA266_RS07845
uniprot id: A1BGL7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

290317:CPHA266 RS07765
gene id: 290317:CPHA266_RS07765
uniprot id: A1BGK2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

290317:CPHA266 RS06800
gene id: 290317:CPHA266_RS06800
uniprot id: A1BG26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

290317:CPHA266 RS02070
gene id: 290317:CPHA266_RS02070
uniprot id: A1BDI0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

290317:CPHA266 RS07940
gene id: 290317:CPHA266_RS07940
uniprot id: A1BGN6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

290317:CPHA266 RS02100
gene id: 290317:CPHA266_RS02100
uniprot id: A1BDI5
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS00910
gene id: 290317:CPHA266_RS00910
uniprot id: A1BCW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

290317:CPHA266 RS03080
gene id: 290317:CPHA266_RS03080
uniprot id: A1BE22
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

290317:CPHA266 RS01920
gene id: 290317:CPHA266_RS01920
uniprot id: A1BDF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

290317:CPHA266 RS09940
gene id: 290317:CPHA266_RS09940
uniprot id: A1BHQ7
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

290317:CPHA266 RS02200
gene id: 290317:CPHA266_RS02200
uniprot id: A1BDK5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

290317:CPHA266 RS05400
gene id: 290317:CPHA266_RS05400
uniprot id: A1BFB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

290317:CPHA266 RS14000
gene id: 290317:CPHA266_RS14000
uniprot id: A1BJV7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

290317:CPHA266 RS04915
gene id: 290317:CPHA266_RS04915
uniprot id: A1BF15
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

290317:CPHA266 RS07265
gene id: 290317:CPHA266_RS07265
uniprot id: A1BGB4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

290317:CPHA266 RS05465
gene id: 290317:CPHA266_RS05465
uniprot id: A1BFC3
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

290317:CPHA266 RS02990
gene id: 290317:CPHA266_RS02990
uniprot id: A1BE04
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

290317:CPHA266 RS09050
gene id: 290317:CPHA266_RS09050
uniprot id: A1BH89
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS02620
gene id: 290317:CPHA266_RS02620
uniprot id: A1BDT2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

290317:CPHA266 RS03745
gene id: 290317:CPHA266_RS03745
uniprot id: A1BEE6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

290317:CPHA266 RS12370
gene id: 290317:CPHA266_RS12370
uniprot id: A1BIZ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BchN/ChlN family.
messages: Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
messages: Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits.

290317:CPHA266 RS11865
gene id: 290317:CPHA266_RS11865
uniprot id: A1BIQ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

290317:CPHA266 RS13985
gene id: 290317:CPHA266_RS13985
uniprot id: A1BJV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

290317:CPHA266 RS03070
gene id: 290317:CPHA266_RS03070
uniprot id: A1BE20
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

290317:CPHA266 RS09690
gene id: 290317:CPHA266_RS09690
uniprot id: A1BHL1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

290317:CPHA266 RS07895
gene id: 290317:CPHA266_RS07895
uniprot id: A1BGM7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

290317:CPHA266 RS00535
gene id: 290317:CPHA266_RS00535
uniprot id: A1BCP3
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

290317:CPHA266 RS08715
gene id: 290317:CPHA266_RS08715
uniprot id: A1BH26
names: Similarity
messages: Belongs to the leucine-binding protein family.

290317:CPHA266 RS15955
gene id: 290317:CPHA266_RS15955
uniprot id: A1BGA0
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

290317:CPHA266 RS07245
gene id: 290317:CPHA266_RS07245
uniprot id: A1BGB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

290317:CPHA266 RS03760
gene id: 290317:CPHA266_RS03760
uniprot id: A1BEE9
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

290317:CPHA266 RS03765
gene id: 290317:CPHA266_RS03765
uniprot id: A1BEF0
names: Similarity
messages: Belongs to the HupF/HypC family.

290317:CPHA266 RS03190
gene id: 290317:CPHA266_RS03190
uniprot id: A1BE42
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

290317:CPHA266 RS12305
gene id: 290317:CPHA266_RS12305
uniprot id: A1BIY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

290317:CPHA266 RS05355
gene id: 290317:CPHA266_RS05355
uniprot id: A1BFA1
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

290317:CPHA266 RS12730
gene id: 290317:CPHA266_RS12730
uniprot id: A1BJ68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

290317:CPHA266 RS13185
gene id: 290317:CPHA266_RS13185
uniprot id: A1BJF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

290317:CPHA266 RS02795
gene id: 290317:CPHA266_RS02795
uniprot id: A1BDW6
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

290317:CPHA266 RS04590
gene id: 290317:CPHA266_RS04590
uniprot id: A1BEV6
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

290317:CPHA266 RS13255
gene id: 290317:CPHA266_RS13255
uniprot id: A1BJG8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

290317:CPHA266 RS04415
gene id: 290317:CPHA266_RS04415
uniprot id: A1BES3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

290317:CPHA266 RS14120
gene id: 290317:CPHA266_RS14120
uniprot id: A1BJY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

290317:CPHA266 RS06190
gene id: 290317:CPHA266_RS06190
uniprot id: A1BFQ6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

290317:CPHA266 RS07045
gene id: 290317:CPHA266_RS07045
uniprot id: A1BG70
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS03195
gene id: 290317:CPHA266_RS03195
uniprot id: A1BE43
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

290317:CPHA266 RS10865
gene id: 290317:CPHA266_RS10865
uniprot id: A1BI73
names: Function
names: Similarity
messages: Belongs to the isochorismate synthase family.
messages: Catalyzes the conversion of chorismate to isochorismate.

290317:CPHA266 RS04730
gene id: 290317:CPHA266_RS04730
uniprot id: A1BEY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

290317:CPHA266 RS12190
gene id: 290317:CPHA266_RS12190
uniprot id: A1BIW3
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

290317:CPHA266 RS04285
gene id: 290317:CPHA266_RS04285
uniprot id: A1BEP9
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

290317:CPHA266 RS07780
gene id: 290317:CPHA266_RS07780
uniprot id: A1BGK5
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS12515
gene id: 290317:CPHA266_RS12515
uniprot id: A1BJ28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

290317:CPHA266 RS00215
gene id: 290317:CPHA266_RS00215
uniprot id: A1BCI7
names: Similarity
messages: Belongs to the geranylgeranyl reductase family. ChlP subfamily.

290317:CPHA266 RS12310
gene id: 290317:CPHA266_RS12310
uniprot id: A1BIY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

290317:CPHA266 RS12460
gene id: 290317:CPHA266_RS12460
uniprot id: A1BJ18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

290317:CPHA266 RS06150
gene id: 290317:CPHA266_RS06150
uniprot id: A1BFP8
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS09575
gene id: 290317:CPHA266_RS09575
uniprot id: A1BHI8
names: Similarity
messages: Belongs to the PucC family.

290317:CPHA266 RS12735
gene id: 290317:CPHA266_RS12735
uniprot id: A1BJ69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

290317:CPHA266 RS06835
gene id: 290317:CPHA266_RS06835
uniprot id: A1BG33
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

290317:CPHA266 RS08100
gene id: 290317:CPHA266_RS08100
uniprot id: A1BGR5
names: Similarity
messages: Belongs to the glutamate synthase family.

290317:CPHA266 RS06750
gene id: 290317:CPHA266_RS06750
uniprot id: A1BG16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

290317:CPHA266 RS02565
gene id: 290317:CPHA266_RS02565
uniprot id: A1BDS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

290317:CPHA266 RS10920
gene id: 290317:CPHA266_RS10920
uniprot id: A1BI84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

290317:CPHA266 RS10275
gene id: 290317:CPHA266_RS10275
uniprot id: A1BHW4
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS00805
gene id: 290317:CPHA266_RS00805
uniprot id: A1BCU5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

290317:CPHA266 RS05070
gene id: 290317:CPHA266_RS05070
uniprot id: A1BF44
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

290317:CPHA266 RS05125
gene id: 290317:CPHA266_RS05125
uniprot id: A1BF55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

290317:CPHA266 RS12270
gene id: 290317:CPHA266_RS12270
uniprot id: A1BIX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

290317:CPHA266 RS09035
gene id: 290317:CPHA266_RS09035
uniprot id: A1BH86
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

290317:CPHA266 RS01985
gene id: 290317:CPHA266_RS01985
uniprot id: A1BDG8
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS10560
gene id: 290317:CPHA266_RS10560
uniprot id: A1BI20
names: Similarity
messages: Belongs to the BshC family.

290317:CPHA266 RS06175
gene id: 290317:CPHA266_RS06175
uniprot id: A1BFQ3
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

290317:CPHA266 RS09830
gene id: 290317:CPHA266_RS09830
uniprot id: A1BHN5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

290317:CPHA266 RS12835
gene id: 290317:CPHA266_RS12835
uniprot id: A1BJ89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

290317:CPHA266 RS03635
gene id: 290317:CPHA266_RS03635
uniprot id: A1BEC6
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS09700
gene id: 290317:CPHA266_RS09700
uniprot id: A1BHL3
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

290317:CPHA266 RS00635
gene id: 290317:CPHA266_RS00635
uniprot id: A1BCR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

290317:CPHA266 RS06125
gene id: 290317:CPHA266_RS06125
uniprot id: A1BFP4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

290317:CPHA266 RS08910
gene id: 290317:CPHA266_RS08910
uniprot id: A1BH63
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

290317:CPHA266 RS10635
gene id: 290317:CPHA266_RS10635
uniprot id: A1BI35
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

290317:CPHA266 RS01665
gene id: 290317:CPHA266_RS01665
uniprot id: A1BDA9
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

290317:CPHA266 RS01715
gene id: 290317:CPHA266_RS01715
uniprot id: A1BDB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

290317:CPHA266 RS03535
gene id: 290317:CPHA266_RS03535
uniprot id: A1BEA7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

290317:CPHA266 RS13050
gene id: 290317:CPHA266_RS13050
uniprot id: A1BJD1
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

290317:CPHA266 RS02315
gene id: 290317:CPHA266_RS02315
uniprot id: A1BDM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

290317:CPHA266 RS03610
gene id: 290317:CPHA266_RS03610
uniprot id: A1BEC1
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS06830
gene id: 290317:CPHA266_RS06830
uniprot id: A1BG32
names: Similarity
messages: Belongs to the peptidase S41A family.

290317:CPHA266 RS07630
gene id: 290317:CPHA266_RS07630
uniprot id: A1BGI0
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

290317:CPHA266 RS03480
gene id: 290317:CPHA266_RS03480
uniprot id: A1BE96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

290317:CPHA266 RS05295
gene id: 290317:CPHA266_RS05295
uniprot id: A1BF89
names: Similarity
messages: Belongs to the SAICAR synthetase family.

290317:CPHA266 RS08780
gene id: 290317:CPHA266_RS08780
uniprot id: A1BH38
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

290317:CPHA266 RS02355
gene id: 290317:CPHA266_RS02355
uniprot id: A1BDN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

290317:CPHA266 RS10440
gene id: 290317:CPHA266_RS10440
uniprot id: A1BHZ5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

290317:CPHA266 RS12295
gene id: 290317:CPHA266_RS12295
uniprot id: A1BIY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

290317:CPHA266 RS10250
gene id: 290317:CPHA266_RS10250
uniprot id: A1BHV9
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

290317:CPHA266 RS04835
gene id: 290317:CPHA266_RS04835
uniprot id: A1BEZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

290317:CPHA266 RS03990
gene id: 290317:CPHA266_RS03990
uniprot id: A1BEJ2
names: Similarity
messages: Belongs to the HepT RNase toxin family.

290317:CPHA266 RS02955
gene id: 290317:CPHA266_RS02955
uniprot id: A1BDZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

290317:CPHA266 RS05075
gene id: 290317:CPHA266_RS05075
uniprot id: A1BF45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

290317:CPHA266 RS06160
gene id: 290317:CPHA266_RS06160
uniprot id: A1BFQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

290317:CPHA266 RS12275
gene id: 290317:CPHA266_RS12275
uniprot id: A1BIY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

290317:CPHA266 RS03500
gene id: 290317:CPHA266_RS03500
uniprot id: A1BEA0
names: Similarity
messages: Belongs to the UPF0047 family.

290317:CPHA266 RS02155
gene id: 290317:CPHA266_RS02155
uniprot id: A1BDJ6
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

290317:CPHA266 RS05730
gene id: 290317:CPHA266_RS05730
uniprot id: A1BFH3
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

290317:CPHA266 RS13730
gene id: 290317:CPHA266_RS13730
uniprot id: A1BCG8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

290317:CPHA266 RS01120
gene id: 290317:CPHA266_RS01120
uniprot id: A1BD08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS01910
gene id: 290317:CPHA266_RS01910
uniprot id: A1BDF3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

290317:CPHA266 RS02820
gene id: 290317:CPHA266_RS02820
uniprot id: A1BDX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

290317:CPHA266 RS07840
gene id: 290317:CPHA266_RS07840
uniprot id: A1BGL6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

290317:CPHA266 RS06965
gene id: 290317:CPHA266_RS06965
uniprot id: A1BG57
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

290317:CPHA266 RS09130
gene id: 290317:CPHA266_RS09130
uniprot id: A1BHA5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

290317:CPHA266 RS10995
gene id: 290317:CPHA266_RS10995
uniprot id: A1BCG8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

290317:CPHA266 RS10810
gene id: 290317:CPHA266_RS10810
uniprot id: A1BI63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

290317:CPHA266 RS03020
gene id: 290317:CPHA266_RS03020
uniprot id: A1BE10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

290317:CPHA266 RS03825
gene id: 290317:CPHA266_RS03825
uniprot id: A1BEG2
names: Similarity
messages: Belongs to the ModE family.

290317:CPHA266 RS01615
gene id: 290317:CPHA266_RS01615
uniprot id: A1BD99
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

290317:CPHA266 RS10460
gene id: 290317:CPHA266_RS10460
uniprot id: A1BHZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

290317:CPHA266 RS08825
gene id: 290317:CPHA266_RS08825
uniprot id: A1BH46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

290317:CPHA266 RS14510
gene id: 290317:CPHA266_RS14510
uniprot id: A1BJU4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

290317:CPHA266 RS13200
gene id: 290317:CPHA266_RS13200
uniprot id: A1BJF7
names: Similarity
messages: Belongs to the threonine synthase family.

290317:CPHA266 RS05985
gene id: 290317:CPHA266_RS05985
uniprot id: A1BFM1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

290317:CPHA266 RS02615
gene id: 290317:CPHA266_RS02615
uniprot id: A1BDT1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

290317:CPHA266 RS12315
gene id: 290317:CPHA266_RS12315
uniprot id: A1BIY8
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

290317:CPHA266 RS12560
gene id: 290317:CPHA266_RS12560
uniprot id: A1BJ37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

290317:CPHA266 RS07930
gene id: 290317:CPHA266_RS07930
uniprot id: A1BGN4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

290317:CPHA266 RS07500
gene id: 290317:CPHA266_RS07500
uniprot id: A1BGF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell inner membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

290317:CPHA266 RS07965
gene id: 290317:CPHA266_RS07965
uniprot id: A1BGP1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

290317:CPHA266 RS10045
gene id: 290317:CPHA266_RS10045
uniprot id: A1BHS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

290317:CPHA266 RS07970
gene id: 290317:CPHA266_RS07970
uniprot id: A1BGP2
names: Similarity
messages: Belongs to the sigma-54 factor family.

290317:CPHA266 RS11900
gene id: 290317:CPHA266_RS11900
uniprot id: A1BIR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BChl C/E-binding protein family.
messages: Component of the photosynthetic apparatus.
messages: chlorosome envelope

290317:CPHA266 RS03055
gene id: 290317:CPHA266_RS03055
uniprot id: A1BE17
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

290317:CPHA266 RS12975
gene id: 290317:CPHA266_RS12975
uniprot id: A1BJB6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

290317:CPHA266 RS12960
gene id: 290317:CPHA266_RS12960
uniprot id: A1BJB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

290317:CPHA266 RS10665
gene id: 290317:CPHA266_RS10665
uniprot id: A1BI40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

290317:CPHA266 RS02130
gene id: 290317:CPHA266_RS02130
uniprot id: A1BDJ1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

290317:CPHA266 RS06485
gene id: 290317:CPHA266_RS06485
uniprot id: A1BFW6
names: Similarity
messages: Belongs to the HdrA family.

290317:CPHA266 RS14190
gene id: 290317:CPHA266_RS14190
uniprot id: A1BJZ4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

290317:CPHA266 RS12345
gene id: 290317:CPHA266_RS12345
uniprot id: A1BCG8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

290317:CPHA266 RS03345
gene id: 290317:CPHA266_RS03345
uniprot id: A1BCG8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

290317:CPHA266 RS11245
gene id: 290317:CPHA266_RS11245
uniprot id: A1BID7
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS14180
gene id: 290317:CPHA266_RS14180
uniprot id: A1BJZ2
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS03245
gene id: 290317:CPHA266_RS03245
uniprot id: A1BE52
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

290317:CPHA266 RS13365
gene id: 290317:CPHA266_RS13365
uniprot id: A1BJJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

290317:CPHA266 RS05725
gene id: 290317:CPHA266_RS05725
uniprot id: A1BFH2
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

290317:CPHA266 RS09910
gene id: 290317:CPHA266_RS09910
uniprot id: A1BHQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

290317:CPHA266 RS06775
gene id: 290317:CPHA266_RS06775
uniprot id: A1BG21
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS10120
gene id: 290317:CPHA266_RS10120
uniprot id: A1BHT8
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

290317:CPHA266 RS09805
gene id: 290317:CPHA266_RS09805
uniprot id: A1BHN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

290317:CPHA266 RS12200
gene id: 290317:CPHA266_RS12200
uniprot id: A1BIW5
names: Subcellular Location Annotation
messages: Cytoplasm

290317:CPHA266 RS10620
gene id: 290317:CPHA266_RS10620
uniprot id: A1BI32
names: Similarity
messages: Belongs to the CRISPR-associated Csm4 family.

290317:CPHA266 RS07905
gene id: 290317:CPHA266_RS07905
uniprot id: A1BGM9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

290317:CPHA266 RS05180
gene id: 290317:CPHA266_RS05180
uniprot id: A1BF67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

290317:CPHA266 RS02775
gene id: 290317:CPHA266_RS02775
uniprot id: A1BDW2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS04910
gene id: 290317:CPHA266_RS04910
uniprot id: A1BF14
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

290317:CPHA266 RS10785
gene id: 290317:CPHA266_RS10785
uniprot id: A1BI58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

290317:CPHA266 RS02150
gene id: 290317:CPHA266_RS02150
uniprot id: A1BDJ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

290317:CPHA266 RS04400
gene id: 290317:CPHA266_RS04400
uniprot id: A1BES0
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

290317:CPHA266 RS10505
gene id: 290317:CPHA266_RS10505
uniprot id: A1BI09
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

290317:CPHA266 RS10380
gene id: 290317:CPHA266_RS10380
uniprot id: A1BHY4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

290317:CPHA266 RS00160
gene id: 290317:CPHA266_RS00160
uniprot id: A1BCH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

290317:CPHA266 RS04425
gene id: 290317:CPHA266_RS04425
uniprot id: A1BES5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

290317:CPHA266 RS01895
gene id: 290317:CPHA266_RS01895
uniprot id: A1BDF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

290317:CPHA266 RS05040
gene id: 290317:CPHA266_RS05040
uniprot id: A1BF38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

290317:CPHA266 RS02435
gene id: 290317:CPHA266_RS02435
uniprot id: A1BDP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

290317:CPHA266 RS12450
gene id: 290317:CPHA266_RS12450
uniprot id: A1BJ16
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

290317:CPHA266 RS00985
gene id: 290317:CPHA266_RS00985
uniprot id: A1BCX9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

290317:CPHA266 RS04540
gene id: 290317:CPHA266_RS04540
uniprot id: A1BEU6
names: Similarity
messages: Belongs to the AlaDH/PNT family.

290317:CPHA266 RS11890
gene id: 290317:CPHA266_RS11890
uniprot id: A1BIR2
names: Similarity
messages: Belongs to the arsA ATPase family.

290317:CPHA266 RS10820
gene id: 290317:CPHA266_RS10820
uniprot id: A1BI65
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

290317:CPHA266 RS06185
gene id: 290317:CPHA266_RS06185
uniprot id: A1BFQ5
names: Similarity
messages: Belongs to the thioredoxin family.

290317:CPHA266 RS03655
gene id: 290317:CPHA266_RS03655
uniprot id: A1BED0
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

290317:CPHA266 RS09600
gene id: 290317:CPHA266_RS09600
uniprot id: A1BHJ3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

290317:CPHA266 RS02635
gene id: 290317:CPHA266_RS02635
uniprot id: A1BDT5
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

290317:CPHA266 RS06855
gene id: 290317:CPHA266_RS06855
uniprot id: A1BG37
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

290317:CPHA266 RS03630
gene id: 290317:CPHA266_RS03630
uniprot id: A1BEC5
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS08575
gene id: 290317:CPHA266_RS08575
uniprot id: A1BGZ8
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS01230
gene id: 290317:CPHA266_RS01230
uniprot id: A1BD26
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

290317:CPHA266 RS05030
gene id: 290317:CPHA266_RS05030
uniprot id: A1BF36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

290317:CPHA266 RS08070
gene id: 290317:CPHA266_RS08070
uniprot id: A1BGR0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

290317:CPHA266 RS02905
gene id: 290317:CPHA266_RS02905
uniprot id: A1BDY7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

290317:CPHA266 RS12900
gene id: 290317:CPHA266_RS12900
uniprot id: A1BJA1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

290317:CPHA266 RS12405
gene id: 290317:CPHA266_RS12405
uniprot id: A1BJ06
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

290317:CPHA266 RS01930
gene id: 290317:CPHA266_RS01930
uniprot id: A1BDF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

290317:CPHA266 RS11195
gene id: 290317:CPHA266_RS11195
uniprot id: A1BIC7
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

290317:CPHA266 RS01995
gene id: 290317:CPHA266_RS01995
uniprot id: A1BDH0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

290317:CPHA266 RS04895
gene id: 290317:CPHA266_RS04895
uniprot id: A1BF11
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS12430
gene id: 290317:CPHA266_RS12430
uniprot id: A1BJ12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

290317:CPHA266 RS01105
gene id: 290317:CPHA266_RS01105
uniprot id: A1BD05
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

290317:CPHA266 RS01970
gene id: 290317:CPHA266_RS01970
uniprot id: A1BDG5
names: Similarity
messages: Belongs to the DprA/Smf family.

290317:CPHA266 RS14010
gene id: 290317:CPHA266_RS14010
uniprot id: A1BJV9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

290317:CPHA266 RS12580
gene id: 290317:CPHA266_RS12580
uniprot id: A1BJ41
names: Similarity
messages: Belongs to the YjdM family.

290317:CPHA266 RS02165
gene id: 290317:CPHA266_RS02165
uniprot id: A1BDJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

290317:CPHA266 RS07375
gene id: 290317:CPHA266_RS07375
uniprot id: A1BGD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

290317:CPHA266 RS13145
gene id: 290317:CPHA266_RS13145
uniprot id: A1BJE7
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

290317:CPHA266 RS06080
gene id: 290317:CPHA266_RS06080
uniprot id: A1BFN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

290317:CPHA266 RS14085
gene id: 290317:CPHA266_RS14085
uniprot id: A1BJX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS12525
gene id: 290317:CPHA266_RS12525
uniprot id: A1BJ30
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

290317:CPHA266 RS03875
gene id: 290317:CPHA266_RS03875
uniprot id: A1BEH1
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS04235
gene id: 290317:CPHA266_RS04235
uniprot id: A1BEN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

290317:CPHA266 RS01185
gene id: 290317:CPHA266_RS01185
uniprot id: A1BD17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

290317:CPHA266 RS12380
gene id: 290317:CPHA266_RS12380
uniprot id: A1BJ01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

290317:CPHA266 RS12890
gene id: 290317:CPHA266_RS12890
uniprot id: A1BJ99
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

290317:CPHA266 RS02500
gene id: 290317:CPHA266_RS02500
uniprot id: A1BDQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

290317:CPHA266 RS13910
gene id: 290317:CPHA266_RS13910
uniprot id: A1BJT9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

290317:CPHA266 RS14205
gene id: 290317:CPHA266_RS14205
uniprot id: A1BJZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

290317:CPHA266 RS12475
gene id: 290317:CPHA266_RS12475
uniprot id: A1BJ21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

290317:CPHA266 RS09555
gene id: 290317:CPHA266_RS09555
uniprot id: A1BHI4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

290317:CPHA266 RS00240
gene id: 290317:CPHA266_RS00240
uniprot id: A1BCJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

290317:CPHA266 RS13315
gene id: 290317:CPHA266_RS13315
uniprot id: A1BJI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

290317:CPHA266 RS05055
gene id: 290317:CPHA266_RS05055
uniprot id: A1BF41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

290317:CPHA266 RS04350
gene id: 290317:CPHA266_RS04350
uniprot id: A1BER0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS01750
gene id: 290317:CPHA266_RS01750
uniprot id: A1BDC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

290317:CPHA266 RS02970
gene id: 290317:CPHA266_RS02970
uniprot id: A1BE00
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

290317:CPHA266 RS00410
gene id: 290317:CPHA266_RS00410
uniprot id: A1BCG8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

290317:CPHA266 RS03855
gene id: 290317:CPHA266_RS03855
uniprot id: A1BEG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

290317:CPHA266 RS12385
gene id: 290317:CPHA266_RS12385
uniprot id: A1BJ02
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

290317:CPHA266 RS04030
gene id: 290317:CPHA266_RS04030
uniprot id: A1BEK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

290317:CPHA266 RS06765
gene id: 290317:CPHA266_RS06765
uniprot id: A1BG19
names: Similarity
messages: Belongs to the rubredoxin family.

290317:CPHA266 RS02505
gene id: 290317:CPHA266_RS02505
uniprot id: A1BDR0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

290317:CPHA266 RS04025
gene id: 290317:CPHA266_RS04025
uniprot id: A1BEK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

290317:CPHA266 RS14035
gene id: 290317:CPHA266_RS14035
uniprot id: A1BJW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

290317:CPHA266 RS11840
gene id: 290317:CPHA266_RS11840
uniprot id: A1BIQ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS12915
gene id: 290317:CPHA266_RS12915
uniprot id: A1BJA4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

290317:CPHA266 RS10870
gene id: 290317:CPHA266_RS10870
uniprot id: A1BI74
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

290317:CPHA266 RS04375
gene id: 290317:CPHA266_RS04375
uniprot id: A1BER5
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS07770
gene id: 290317:CPHA266_RS07770
uniprot id: A1BGK3
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS00595
gene id: 290317:CPHA266_RS00595
uniprot id: A1BCQ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

290317:CPHA266 RS10330
gene id: 290317:CPHA266_RS10330
uniprot id: A1BHX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

290317:CPHA266 RS05050
gene id: 290317:CPHA266_RS05050
uniprot id: A1BF40
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS02815
gene id: 290317:CPHA266_RS02815
uniprot id: A1BDX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

290317:CPHA266 RS08920
gene id: 290317:CPHA266_RS08920
uniprot id: A1BH65
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

290317:CPHA266 RS01725
gene id: 290317:CPHA266_RS01725
uniprot id: A1BDB8
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

290317:CPHA266 RS05815
gene id: 290317:CPHA266_RS05815
uniprot id: A1BFJ0
names: Similarity
messages: Belongs to the DprA/Smf family.

290317:CPHA266 RS03040
gene id: 290317:CPHA266_RS03040
uniprot id: A1BE14
names: Similarity
messages: Belongs to the peptidase M24B family.

290317:CPHA266 RS11920
gene id: 290317:CPHA266_RS11920
uniprot id: A1BIR8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS09305
gene id: 290317:CPHA266_RS09305
uniprot id: A1BHD9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

290317:CPHA266 RS09215
gene id: 290317:CPHA266_RS09215
uniprot id: A1BHC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

290317:CPHA266 RS11870
gene id: 290317:CPHA266_RS11870
uniprot id: A1BIQ8
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

290317:CPHA266 RS09665
gene id: 290317:CPHA266_RS09665
uniprot id: A1BHK6
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS12950
gene id: 290317:CPHA266_RS12950
uniprot id: A1BJB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ChlB/BchB/BchZ family.
messages: Chlorophyllide reductase is composed of three subunits; BchX, BchY and BchZ. Forms a heterodimer of one BchY and one BchZ subunit.
messages: Converts chlorophylls (Chl) into bacteriochlorophylls (BChl) by reducing ring B of the tetrapyrrole.

290317:CPHA266 RS08500
gene id: 290317:CPHA266_RS08500
uniprot id: A1BGY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

290317:CPHA266 RS10545
gene id: 290317:CPHA266_RS10545
uniprot id: A1BI17
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

290317:CPHA266 RS08120
gene id: 290317:CPHA266_RS08120
uniprot id: A1BGR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

290317:CPHA266 RS13810
gene id: 290317:CPHA266_RS13810
uniprot id: A1BJS0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

290317:CPHA266 RS14130
gene id: 290317:CPHA266_RS14130
uniprot id: A1BJY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

290317:CPHA266 RS03305
gene id: 290317:CPHA266_RS03305
uniprot id: A1BE63
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

290317:CPHA266 RS01205
gene id: 290317:CPHA266_RS01205
uniprot id: A1BD21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

290317:CPHA266 RS10435
gene id: 290317:CPHA266_RS10435
uniprot id: A1BHZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

290317:CPHA266 RS13500
gene id: 290317:CPHA266_RS13500
uniprot id: A1BJL6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

290317:CPHA266 RS12830
gene id: 290317:CPHA266_RS12830
uniprot id: A1BJ88
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

290317:CPHA266 RS04210
gene id: 290317:CPHA266_RS04210
uniprot id: A1BEN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

290317:CPHA266 RS02995
gene id: 290317:CPHA266_RS02995
uniprot id: A1BE05
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

290317:CPHA266 RS13375
gene id: 290317:CPHA266_RS13375
uniprot id: A1BJJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

290317:CPHA266 RS08645
gene id: 290317:CPHA266_RS08645
uniprot id: A1BH12
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS11295
gene id: 290317:CPHA266_RS11295
uniprot id: A1BIE7
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

290317:CPHA266 RS06910
gene id: 290317:CPHA266_RS06910
uniprot id: A1BG48
names: Similarity
messages: Belongs to the peptidase C40 family.

290317:CPHA266 RS03235
gene id: 290317:CPHA266_RS03235
uniprot id: A1BE50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
messages: Cell inner membrane
messages: Homodimer.
messages: Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.

290317:CPHA266 RS00615
gene id: 290317:CPHA266_RS00615
uniprot id: A1BCQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS10180
gene id: 290317:CPHA266_RS10180
uniprot id: A1BHU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

290317:CPHA266 RS13390
gene id: 290317:CPHA266_RS13390
uniprot id: A1BJJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

290317:CPHA266 RS13440
gene id: 290317:CPHA266_RS13440
uniprot id: A1BJK6
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

290317:CPHA266 RS04945
gene id: 290317:CPHA266_RS04945
uniprot id: A1BF21
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

290317:CPHA266 RS10950
gene id: 290317:CPHA266_RS10950
uniprot id: A1BI90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

290317:CPHA266 RS06705
gene id: 290317:CPHA266_RS06705
uniprot id: A1BG08
names: Similarity
messages: Belongs to the peptidase S41A family.

290317:CPHA266 RS00810
gene id: 290317:CPHA266_RS00810
uniprot id: A1BCU6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

290317:CPHA266 RS11790
gene id: 290317:CPHA266_RS11790
uniprot id: A1BIP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

290317:CPHA266 RS02290
gene id: 290317:CPHA266_RS02290
uniprot id: A1BDM1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

290317:CPHA266 RS06755
gene id: 290317:CPHA266_RS06755
uniprot id: A1BG17
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

290317:CPHA266 RS02585
gene id: 290317:CPHA266_RS02585
uniprot id: A1BDS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

290317:CPHA266 RS03880
gene id: 290317:CPHA266_RS03880
uniprot id: A1BEH2
names: Similarity
messages: Belongs to the AdoMet synthetase 2 family.

290317:CPHA266 RS14115
gene id: 290317:CPHA266_RS14115
uniprot id: A1BJX9
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS05410
gene id: 290317:CPHA266_RS05410
uniprot id: A1BFB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

290317:CPHA266 RS05100
gene id: 290317:CPHA266_RS05100
uniprot id: A1BF50
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

290317:CPHA266 RS03150
gene id: 290317:CPHA266_RS03150
uniprot id: A1BE34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

290317:CPHA266 RS02555
gene id: 290317:CPHA266_RS02555
uniprot id: A1BDS0
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

290317:CPHA266 RS02530
gene id: 290317:CPHA266_RS02530
uniprot id: A1BDR5
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS09105
gene id: 290317:CPHA266_RS09105
uniprot id: A1BHA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

290317:CPHA266 RS02680
gene id: 290317:CPHA266_RS02680
uniprot id: A1BDU4
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS04900
gene id: 290317:CPHA266_RS04900
uniprot id: A1BF12
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

290317:CPHA266 RS03580
gene id: 290317:CPHA266_RS03580
uniprot id: A1BEB5
names: Similarity
messages: Belongs to the RecJ family.

290317:CPHA266 RS00580
gene id: 290317:CPHA266_RS00580
uniprot id: A1BCQ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

290317:CPHA266 RS11060
gene id: 290317:CPHA266_RS11060
uniprot id: A1BIA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

290317:CPHA266 RS09040
gene id: 290317:CPHA266_RS09040
uniprot id: A1BH87
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

290317:CPHA266 RS03575
gene id: 290317:CPHA266_RS03575
uniprot id: A1BEB4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

290317:CPHA266 RS09140
gene id: 290317:CPHA266_RS09140
uniprot id: A1BHA7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

290317:CPHA266 RS11980
gene id: 290317:CPHA266_RS11980
uniprot id: A1BIS7
names: Similarity
messages: Belongs to the Mg-chelatase subunit H family.

290317:CPHA266 RS03240
gene id: 290317:CPHA266_RS03240
uniprot id: A1BE51
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

290317:CPHA266 RS09180
gene id: 290317:CPHA266_RS09180
uniprot id: A1BHB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

290317:CPHA266 RS05360
gene id: 290317:CPHA266_RS05360
uniprot id: A1BFA2
names: Similarity
messages: Belongs to the peptidase S24 family.

290317:CPHA266 RS04490
gene id: 290317:CPHA266_RS04490
uniprot id: A1BET8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

290317:CPHA266 RS12920
gene id: 290317:CPHA266_RS12920
uniprot id: A1BJA5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

290317:CPHA266 RS10520
gene id: 290317:CPHA266_RS10520
uniprot id: A1BI12
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

290317:CPHA266 RS01905
gene id: 290317:CPHA266_RS01905
uniprot id: A1BDF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

290317:CPHA266 RS08990
gene id: 290317:CPHA266_RS08990
uniprot id: A1BH77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

290317:CPHA266 RS01980
gene id: 290317:CPHA266_RS01980
uniprot id: A1BDG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).

290317:CPHA266 RS03645
gene id: 290317:CPHA266_RS03645
uniprot id: A1BEC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

290317:CPHA266 RS00610
gene id: 290317:CPHA266_RS00610
uniprot id: A1BCQ8
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

290317:CPHA266 RS03705
gene id: 290317:CPHA266_RS03705
uniprot id: A1BEE0
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS13645
gene id: 290317:CPHA266_RS13645
uniprot id: A1BJP2
names: Similarity
messages: Belongs to the polysaccharide synthase family.

290317:CPHA266 RS05140
gene id: 290317:CPHA266_RS05140
uniprot id: A1BF58
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

290317:CPHA266 RS06590
gene id: 290317:CPHA266_RS06590
uniprot id: A1BCG8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

290317:CPHA266 RS05385
gene id: 290317:CPHA266_RS05385
uniprot id: A1BFA7
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

290317:CPHA266 RS12925
gene id: 290317:CPHA266_RS12925
uniprot id: A1BJA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

290317:CPHA266 RS11690
gene id: 290317:CPHA266_RS11690
uniprot id: A1BIM6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

290317:CPHA266 RS14155
gene id: 290317:CPHA266_RS14155
uniprot id: A1BJY7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

290317:CPHA266 RS09445
gene id: 290317:CPHA266_RS09445
uniprot id: A1BHG6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

290317:CPHA266 RS13415
gene id: 290317:CPHA266_RS13415
uniprot id: A1BJK1
names: Similarity
messages: Belongs to the FGGY kinase family.

290317:CPHA266 RS05010
gene id: 290317:CPHA266_RS05010
uniprot id: A1BF32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

290317:CPHA266 RS01245
gene id: 290317:CPHA266_RS01245
uniprot id: A1BD29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

290317:CPHA266 RS09220
gene id: 290317:CPHA266_RS09220
uniprot id: A1BHC2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

290317:CPHA266 RS10500
gene id: 290317:CPHA266_RS10500
uniprot id: A1BI08
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

290317:CPHA266 RS02215
gene id: 290317:CPHA266_RS02215
uniprot id: A1BDK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

290317:CPHA266 RS03615
gene id: 290317:CPHA266_RS03615
uniprot id: A1BEC2
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

290317:CPHA266 RS10280
gene id: 290317:CPHA266_RS10280
uniprot id: A1BHW5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS01215
gene id: 290317:CPHA266_RS01215
uniprot id: A1BD23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

290317:CPHA266 RS08460
gene id: 290317:CPHA266_RS08460
uniprot id: A1BGX7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

290317:CPHA266 RS10030
gene id: 290317:CPHA266_RS10030
uniprot id: A1BHS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

290317:CPHA266 RS03870
gene id: 290317:CPHA266_RS03870
uniprot id: A1BEH0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

290317:CPHA266 RS09100
gene id: 290317:CPHA266_RS09100
uniprot id: A1BH99
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS02830
gene id: 290317:CPHA266_RS02830
uniprot id: A1BDX3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

290317:CPHA266 RS02675
gene id: 290317:CPHA266_RS02675
uniprot id: A1BDU3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

290317:CPHA266 RS13905
gene id: 290317:CPHA266_RS13905
uniprot id: A1BJT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

290317:CPHA266 RS13010
gene id: 290317:CPHA266_RS13010
uniprot id: A1BJC3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

290317:CPHA266 RS04380
gene id: 290317:CPHA266_RS04380
uniprot id: A1BER6
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS06015
gene id: 290317:CPHA266_RS06015
uniprot id: A1BFM7
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

290317:CPHA266 RS03640
gene id: 290317:CPHA266_RS03640
uniprot id: A1BEC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

290317:CPHA266 RS10630
gene id: 290317:CPHA266_RS10630
uniprot id: A1BI34
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm2 family.
messages: This subunit may be involved in monitoring complementarity of crRNA and target RNA.

290317:CPHA266 RS13265
gene id: 290317:CPHA266_RS13265
uniprot id: A1BJH0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

290317:CPHA266 RS09565
gene id: 290317:CPHA266_RS09565
uniprot id: A1BHI6
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

290317:CPHA266 RS10875
gene id: 290317:CPHA266_RS10875
uniprot id: A1BI75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

290317:CPHA266 RS06035
gene id: 290317:CPHA266_RS06035
uniprot id: A1BFN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

290317:CPHA266 RS00700
gene id: 290317:CPHA266_RS00700
uniprot id: A1BCS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

290317:CPHA266 RS00670
gene id: 290317:CPHA266_RS00670
uniprot id: A1BCR9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

290317:CPHA266 RS06145
gene id: 290317:CPHA266_RS06145
uniprot id: A1BFP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

290317:CPHA266 RS03470
gene id: 290317:CPHA266_RS03470
uniprot id: A1BE94
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

290317:CPHA266 RS00755
gene id: 290317:CPHA266_RS00755
uniprot id: A1BCT5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

290317:CPHA266 RS09885
gene id: 290317:CPHA266_RS09885
uniprot id: A1BHP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

290317:CPHA266 RS08615
gene id: 290317:CPHA266_RS08615
uniprot id: A1BH06
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

290317:CPHA266 RS13065
gene id: 290317:CPHA266_RS13065
uniprot id: A1BJD5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

290317:CPHA266 RS13815
gene id: 290317:CPHA266_RS13815
uniprot id: A1BJS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

290317:CPHA266 RS12570
gene id: 290317:CPHA266_RS12570
uniprot id: A1BJ39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

290317:CPHA266 RS12130
gene id: 290317:CPHA266_RS12130
uniprot id: A1BIV5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

290317:CPHA266 RS02985
gene id: 290317:CPHA266_RS02985
uniprot id: A1BE03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

290317:CPHA266 RS08635
gene id: 290317:CPHA266_RS08635
uniprot id: A1BH10
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

290317:CPHA266 RS04965
gene id: 290317:CPHA266_RS04965
uniprot id: A1BF25
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

290317:CPHA266 RS05395
gene id: 290317:CPHA266_RS05395
uniprot id: A1BFA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

290317:CPHA266 RS04815
gene id: 290317:CPHA266_RS04815
uniprot id: A1BEZ6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

290317:CPHA266 RS10530
gene id: 290317:CPHA266_RS10530
uniprot id: A1BI14
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

290317:CPHA266 RS06410
gene id: 290317:CPHA266_RS06410
uniprot id: A1BFV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

290317:CPHA266 RS00705
gene id: 290317:CPHA266_RS00705
uniprot id: A1BCS6
names: Similarity
messages: Belongs to the DsrF/TusC family.

290317:CPHA266 RS13855
gene id: 290317:CPHA266_RS13855
uniprot id: A1BJS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

290317:CPHA266 RS11875
gene id: 290317:CPHA266_RS11875
uniprot id: A1BIQ9
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

290317:CPHA266 RS09875
gene id: 290317:CPHA266_RS09875
uniprot id: A1BHP4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

290317:CPHA266 RS09000
gene id: 290317:CPHA266_RS09000
uniprot id: A1BH79
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

290317:CPHA266 RS05995
gene id: 290317:CPHA266_RS05995
uniprot id: A1BFM3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

290317:CPHA266 RS05780
gene id: 290317:CPHA266_RS05780
uniprot id: A1BFI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

290317:CPHA266 RS00470
gene id: 290317:CPHA266_RS00470
uniprot id: A1BCN0
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS11240
gene id: 290317:CPHA266_RS11240
uniprot id: A1BID6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

290317:CPHA266 RS12480
gene id: 290317:CPHA266_RS12480
uniprot id: A1BJ22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

290317:CPHA266 RS12505
gene id: 290317:CPHA266_RS12505
uniprot id: A1BJ26
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

290317:CPHA266 RS09335
gene id: 290317:CPHA266_RS09335
uniprot id: A1BHE5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

290317:CPHA266 RS08450
gene id: 290317:CPHA266_RS08450
uniprot id: A1BGX5
names: Function
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.
messages: Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.

290317:CPHA266 RS12360
gene id: 290317:CPHA266_RS12360
uniprot id: A1BIZ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
messages: Homodimer. Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB.

290317:CPHA266 RS05135
gene id: 290317:CPHA266_RS05135
uniprot id: A1BF57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

290317:CPHA266 RS11190
gene id: 290317:CPHA266_RS11190
uniprot id: A1BIC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

290317:CPHA266 RS08680
gene id: 290317:CPHA266_RS08680
uniprot id: A1BH19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

290317:CPHA266 RS02360
gene id: 290317:CPHA266_RS02360
uniprot id: A1BDN5
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

290317:CPHA266 RS09750
gene id: 290317:CPHA266_RS09750
uniprot id: A1BHM3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

290317:CPHA266 RS01915
gene id: 290317:CPHA266_RS01915
uniprot id: A1BDF4
names: Similarity
messages: Belongs to the ribF family.

290317:CPHA266 RS10595
gene id: 290317:CPHA266_RS10595
uniprot id: A1BCG8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

290317:CPHA266 RS02865
gene id: 290317:CPHA266_RS02865
uniprot id: A1BDX9
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS01990
gene id: 290317:CPHA266_RS01990
uniprot id: A1BDG9
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS11135
gene id: 290317:CPHA266_RS11135
uniprot id: A1BIB5
names: Similarity
messages: Belongs to the MT-A70-like family.

290317:CPHA266 RS03530
gene id: 290317:CPHA266_RS03530
uniprot id: A1BEA6
names: Similarity
messages: Belongs to the arsA ATPase family.

290317:CPHA266 RS11285
gene id: 290317:CPHA266_RS11285
uniprot id: A1BIE5
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

290317:CPHA266 RS00675
gene id: 290317:CPHA266_RS00675
uniprot id: A1BCS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

290317:CPHA266 RS03280
gene id: 290317:CPHA266_RS03280
uniprot id: A1BE59
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

290317:CPHA266 RS07475
gene id: 290317:CPHA266_RS07475
uniprot id: A1BCG8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

290317:CPHA266 RS09045
gene id: 290317:CPHA266_RS09045
uniprot id: A1BH88
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS03205
gene id: 290317:CPHA266_RS03205
uniprot id: A1BE45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

290317:CPHA266 RS06515
gene id: 290317:CPHA266_RS06515
uniprot id: A1BFX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

290317:CPHA266 RS13180
gene id: 290317:CPHA266_RS13180
uniprot id: A1BJF3
names: Similarity
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

290317:CPHA266 RS03465
gene id: 290317:CPHA266_RS03465
uniprot id: A1BE93
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

290317:CPHA266 RS12235
gene id: 290317:CPHA266_RS12235
uniprot id: A1BIX2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

290317:CPHA266 RS03925
gene id: 290317:CPHA266_RS03925
uniprot id: A1BEI1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

290317:CPHA266 RS03180
gene id: 290317:CPHA266_RS03180
uniprot id: A1BE40
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

290317:CPHA266 RS12390
gene id: 290317:CPHA266_RS12390
uniprot id: A1BJ03
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

290317:CPHA266 RS02295
gene id: 290317:CPHA266_RS02295
uniprot id: A1BDM2
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

290317:CPHA266 RS12565
gene id: 290317:CPHA266_RS12565
uniprot id: A1BJ38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

290317:CPHA266 RS09295
gene id: 290317:CPHA266_RS09295
uniprot id: A1BHD7
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

290317:CPHA266 RS04420
gene id: 290317:CPHA266_RS04420
uniprot id: A1BES4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

290317:CPHA266 RS06495
gene id: 290317:CPHA266_RS06495
uniprot id: A1BFW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

290317:CPHA266 RS06810
gene id: 290317:CPHA266_RS06810
uniprot id: A1BG28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

290317:CPHA266 RS05990
gene id: 290317:CPHA266_RS05990
uniprot id: A1BFM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

290317:CPHA266 RS11470
gene id: 290317:CPHA266_RS11470
uniprot id: A1BCG8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

290317:CPHA266 RS12215
gene id: 290317:CPHA266_RS12215
uniprot id: A1BIW8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

290317:CPHA266 RS07250
gene id: 290317:CPHA266_RS07250
uniprot id: A1BGB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

290317:CPHA266 RS05760
gene id: 290317:CPHA266_RS05760
uniprot id: A1BFH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

290317:CPHA266 RS02945
gene id: 290317:CPHA266_RS02945
uniprot id: A1BDZ5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

290317:CPHA266 RS09635
gene id: 290317:CPHA266_RS09635
uniprot id: A1BHK0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

290317:CPHA266 RS00665
gene id: 290317:CPHA266_RS00665
uniprot id: A1BCR8
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

290317:CPHA266 RS13965
gene id: 290317:CPHA266_RS13965
uniprot id: A1BJV0
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

290317:CPHA266 RS00855
gene id: 290317:CPHA266_RS00855
uniprot id: A1BCV4
names: Similarity
messages: Belongs to the UPF0677 family.

290317:CPHA266 RS01160
gene id: 290317:CPHA266_RS01160
uniprot id: A1BD16
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

290317:CPHA266 RS06040
gene id: 290317:CPHA266_RS06040
uniprot id: A1BFN2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

290317:CPHA266 RS14080
gene id: 290317:CPHA266_RS14080
uniprot id: A1BJX2
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

290317:CPHA266 RS00155
gene id: 290317:CPHA266_RS00155
uniprot id: A1BCH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

290317:CPHA266 RS02915
gene id: 290317:CPHA266_RS02915
uniprot id: A1BDY9
names: PTM
messages: Binds 1 heme group per subunit.

290317:CPHA266 RS12670
gene id: 290317:CPHA266_RS12670
uniprot id: A1BJ57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

290317:CPHA266 RS05470
gene id: 290317:CPHA266_RS05470
uniprot id: A1BFC4
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

290317:CPHA266 RS01770
gene id: 290317:CPHA266_RS01770
uniprot id: A1BDC7
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS04610
gene id: 290317:CPHA266_RS04610
uniprot id: A1BEW0
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS14485
gene id: 290317:CPHA266_RS14485
uniprot id: A1BJD2
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

290317:CPHA266 RS00925
gene id: 290317:CPHA266_RS00925
uniprot id: A1BCW7
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

290317:CPHA266 RS10040
gene id: 290317:CPHA266_RS10040
uniprot id: A1BHS4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

290317:CPHA266 RS06725
gene id: 290317:CPHA266_RS06725
uniprot id: A1BG11
names: Similarity
messages: In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
messages: In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.

290317:CPHA266 RS07275
gene id: 290317:CPHA266_RS07275
uniprot id: A1BGB6
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS00770
gene id: 290317:CPHA266_RS00770
uniprot id: A1BCT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

290317:CPHA266 RS11845
gene id: 290317:CPHA266_RS11845
uniprot id: A1BIQ3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

290317:CPHA266 RS05190
gene id: 290317:CPHA266_RS05190
uniprot id: A1BF69
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

290317:CPHA266 RS13300
gene id: 290317:CPHA266_RS13300
uniprot id: A1BCG8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

290317:CPHA266 RS05590
gene id: 290317:CPHA266_RS05590
uniprot id: A1BFE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

290317:CPHA266 RS07370
gene id: 290317:CPHA266_RS07370
uniprot id: A1BGD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

290317:CPHA266 RS01195
gene id: 290317:CPHA266_RS01195
uniprot id: A1BD19
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

290317:CPHA266 RS04330
gene id: 290317:CPHA266_RS04330
uniprot id: A1BEQ6
names: Similarity
messages: Belongs to the glutamine synthetase family.

290317:CPHA266 RS05755
gene id: 290317:CPHA266_RS05755
uniprot id: A1BFH7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

290317:CPHA266 RS11995
gene id: 290317:CPHA266_RS11995
uniprot id: A1BIT0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

290317:CPHA266 RS06730
gene id: 290317:CPHA266_RS06730
uniprot id: A1BG12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

290317:CPHA266 RS07705
gene id: 290317:CPHA266_RS07705
uniprot id: A1BGJ2
names: Similarity
messages: Belongs to the HsdR family.

290317:CPHA266 RS06860
gene id: 290317:CPHA266_RS06860
uniprot id: A1BG38
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

290317:CPHA266 RS06825
gene id: 290317:CPHA266_RS06825
uniprot id: A1BG31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

290317:CPHA266 RS01210
gene id: 290317:CPHA266_RS01210
uniprot id: A1BD22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

290317:CPHA266 RS04345
gene id: 290317:CPHA266_RS04345
uniprot id: A1BEQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

290317:CPHA266 RS14945
gene id: 290317:CPHA266_RS14945
uniprot id: A1BJ11
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

290317:CPHA266 RS04450
gene id: 290317:CPHA266_RS04450
uniprot id: A1BET0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

290317:CPHA266 RS01300
gene id: 290317:CPHA266_RS01300
uniprot id: A1BD40
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

290317:CPHA266 RS13845
gene id: 290317:CPHA266_RS13845
uniprot id: A1BJS7
names: Similarity
messages: Belongs to the peptidase C1 family.

290317:CPHA266 RS06770
gene id: 290317:CPHA266_RS06770
uniprot id: A1BG20
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS01815
gene id: 290317:CPHA266_RS01815
uniprot id: A1BDD5
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS12545
gene id: 290317:CPHA266_RS12545
uniprot id: A1BJ34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

290317:CPHA266 RS07380
gene id: 290317:CPHA266_RS07380
uniprot id: A1BGD3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

290317:CPHA266 RS08895
gene id: 290317:CPHA266_RS08895
uniprot id: A1BH60
names: Similarity
messages: Belongs to the thioredoxin family.

290317:CPHA266 RS12455
gene id: 290317:CPHA266_RS12455
uniprot id: A1BJ17
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

290317:CPHA266 RS03525
gene id: 290317:CPHA266_RS03525
uniprot id: A1BEA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

290317:CPHA266 RS07850
gene id: 290317:CPHA266_RS07850
uniprot id: A1BGL8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

290317:CPHA266 RS00740
gene id: 290317:CPHA266_RS00740
uniprot id: A1BCT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

290317:CPHA266 RS05675
gene id: 290317:CPHA266_RS05675
uniprot id: A1BFG2
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS09115
gene id: 290317:CPHA266_RS09115
uniprot id: A1BHA2
names: Subcellular Location Annotation
messages: Cytoplasm

290317:CPHA266 RS12445
gene id: 290317:CPHA266_RS12445
uniprot id: A1BJ15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

290317:CPHA266 RS12375
gene id: 290317:CPHA266_RS12375
uniprot id: A1BJ00
names: Similarity
messages: Belongs to the UPF0045 family.

290317:CPHA266 RS12495
gene id: 290317:CPHA266_RS12495
uniprot id: A1BJ24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

290317:CPHA266 RS09135
gene id: 290317:CPHA266_RS09135
uniprot id: A1BHA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

290317:CPHA266 RS03685
gene id: 290317:CPHA266_RS03685
uniprot id: A1BED6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

290317:CPHA266 RS03085
gene id: 290317:CPHA266_RS03085
uniprot id: A1BE23
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

290317:CPHA266 RS09120
gene id: 290317:CPHA266_RS09120
uniprot id: A1BHA3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

290317:CPHA266 RS03260
gene id: 290317:CPHA266_RS03260
uniprot id: A1BE55
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

290317:CPHA266 RS04150
gene id: 290317:CPHA266_RS04150
uniprot id: A1BEM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

290317:CPHA266 RS01095
gene id: 290317:CPHA266_RS01095
uniprot id: A1BD03
names: Similarity
messages: Belongs to the arsA ATPase family.

290317:CPHA266 RS03095
gene id: 290317:CPHA266_RS03095
uniprot id: A1BE25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

290317:CPHA266 RS11200
gene id: 290317:CPHA266_RS11200
uniprot id: A1BIC8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS07690
gene id: 290317:CPHA266_RS07690
uniprot id: A1BGI9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

290317:CPHA266 RS14045
gene id: 290317:CPHA266_RS14045
uniprot id: A1BJW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has four main subunits: a(1), b(1), b'(1) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta, b and b' chains.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

290317:CPHA266 RS14175
gene id: 290317:CPHA266_RS14175
uniprot id: A1BJZ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

290317:CPHA266 RS08590
gene id: 290317:CPHA266_RS08590
uniprot id: A1BH01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

290317:CPHA266 RS12555
gene id: 290317:CPHA266_RS12555
uniprot id: A1BJ36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

290317:CPHA266 RS07945
gene id: 290317:CPHA266_RS07945
uniprot id: A1BGN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

290317:CPHA266 RS00510
gene id: 290317:CPHA266_RS00510
uniprot id: A1BCN8
names: Similarity
messages: Belongs to the universal stress protein A family.

290317:CPHA266 RS10475
gene id: 290317:CPHA266_RS10475
uniprot id: A1BI02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

290317:CPHA266 RS12255
gene id: 290317:CPHA266_RS12255
uniprot id: A1BIX6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

290317:CPHA266 RS10925
gene id: 290317:CPHA266_RS10925
uniprot id: A1BI85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

290317:CPHA266 RS04850
gene id: 290317:CPHA266_RS04850
uniprot id: A1BF02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

290317:CPHA266 RS03420
gene id: 290317:CPHA266_RS03420
uniprot id: A1BE85
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

290317:CPHA266 RS01755
gene id: 290317:CPHA266_RS01755
uniprot id: A1BDC4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

290317:CPHA266 RS10430
gene id: 290317:CPHA266_RS10430
uniprot id: A1BHZ3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.

290317:CPHA266 RS05630
gene id: 290317:CPHA266_RS05630
uniprot id: A1BFF3
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

290317:CPHA266 RS09650
gene id: 290317:CPHA266_RS09650
uniprot id: A1BHK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS09620
gene id: 290317:CPHA266_RS09620
uniprot id: A1BHJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

290317:CPHA266 RS03970
gene id: 290317:CPHA266_RS03970
uniprot id: A1BEI9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

290317:CPHA266 RS09285
gene id: 290317:CPHA266_RS09285
uniprot id: A1BHD5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

290317:CPHA266 RS07880
gene id: 290317:CPHA266_RS07880
uniprot id: A1BGM4
names: Similarity
messages: Belongs to the peptidase S41A family.

290317:CPHA266 RS07395
gene id: 290317:CPHA266_RS07395
uniprot id: A1BGD6
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

290317:CPHA266 RS03605
gene id: 290317:CPHA266_RS03605
uniprot id: A1BEC0
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

290317:CPHA266 RS09680
gene id: 290317:CPHA266_RS09680
uniprot id: A1BHK9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

290317:CPHA266 RS02745
gene id: 290317:CPHA266_RS02745
uniprot id: A1BDV6
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

290317:CPHA266 RS06545
gene id: 290317:CPHA266_RS06545
uniprot id: A1BFX7
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

290317:CPHA266 RS03755
gene id: 290317:CPHA266_RS03755
uniprot id: A1BEE8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

290317:CPHA266 RS04440
gene id: 290317:CPHA266_RS04440
uniprot id: A1BES8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

290317:CPHA266 RS12815
gene id: 290317:CPHA266_RS12815
uniprot id: A1BJ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

290317:CPHA266 RS00955
gene id: 290317:CPHA266_RS00955
uniprot id: A1BCX3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

290317:CPHA266 RS00440
gene id: 290317:CPHA266_RS00440
uniprot id: A1BCM6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

290317:CPHA266 RS04775
gene id: 290317:CPHA266_RS04775
uniprot id: A1BEZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

290317:CPHA266 RS02205
gene id: 290317:CPHA266_RS02205
uniprot id: A1BDK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

290317:CPHA266 RS12520
gene id: 290317:CPHA266_RS12520
uniprot id: A1BJ29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

290317:CPHA266 RS12910
gene id: 290317:CPHA266_RS12910
uniprot id: A1BJA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

290317:CPHA266 RS02805
gene id: 290317:CPHA266_RS02805
uniprot id: A1BDW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

290317:CPHA266 RS07860
gene id: 290317:CPHA266_RS07860
uniprot id: A1BGM0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

290317:CPHA266 RS10450
gene id: 290317:CPHA266_RS10450
uniprot id: A1BHZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

290317:CPHA266 RS02630
gene id: 290317:CPHA266_RS02630
uniprot id: A1BDT4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

290317:CPHA266 RS02195
gene id: 290317:CPHA266_RS02195
uniprot id: A1BDK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

290317:CPHA266 RS13670
gene id: 290317:CPHA266_RS13670
uniprot id: A1BJP7
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

290317:CPHA266 RS12470
gene id: 290317:CPHA266_RS12470
uniprot id: A1BJ20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

290317:CPHA266 RS06460
gene id: 290317:CPHA266_RS06460
uniprot id: A1BFW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS10455
gene id: 290317:CPHA266_RS10455
uniprot id: A1BHZ8
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

290317:CPHA266 RS02705
gene id: 290317:CPHA266_RS02705
uniprot id: A1BDU9
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS02175
gene id: 290317:CPHA266_RS02175
uniprot id: A1BDK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

290317:CPHA266 RS05700
gene id: 290317:CPHA266_RS05700
uniprot id: A1BFG7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

290317:CPHA266 RS05460
gene id: 290317:CPHA266_RS05460
uniprot id: A1BFC2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS02480
gene id: 290317:CPHA266_RS02480
uniprot id: A1BDQ5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

290317:CPHA266 RS14170
gene id: 290317:CPHA266_RS14170
uniprot id: A1BJZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

290317:CPHA266 RS13225
gene id: 290317:CPHA266_RS13225
uniprot id: A1BJG2
names: Similarity
messages: Belongs to the universal stress protein A family.

290317:CPHA266 RS10625
gene id: 290317:CPHA266_RS10625
uniprot id: A1BI33
names: Similarity
messages: Belongs to the CRISPR-associated Csm3 family.

290317:CPHA266 RS08945
gene id: 290317:CPHA266_RS08945
uniprot id: A1BH69
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

290317:CPHA266 RS10390
gene id: 290317:CPHA266_RS10390
uniprot id: A1BHY6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

290317:CPHA266 RS12995
gene id: 290317:CPHA266_RS12995
uniprot id: A1BJC0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

290317:CPHA266 RS03850
gene id: 290317:CPHA266_RS03850
uniprot id: A1BEG6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

290317:CPHA266 RS10880
gene id: 290317:CPHA266_RS10880
uniprot id: A1BI76
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS09705
gene id: 290317:CPHA266_RS09705
uniprot id: A1BHL4
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

290317:CPHA266 RS10355
gene id: 290317:CPHA266_RS10355
uniprot id: A1BHX9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

290317:CPHA266 RS11375
gene id: 290317:CPHA266_RS11375
uniprot id: A1BIG3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

290317:CPHA266 RS13345
gene id: 290317:CPHA266_RS13345
uniprot id: A1BJI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

290317:CPHA266 RS04640
gene id: 290317:CPHA266_RS04640
uniprot id: A1BEW6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

290317:CPHA266 RS14105
gene id: 290317:CPHA266_RS14105
uniprot id: A1BJX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

290317:CPHA266 RS03695
gene id: 290317:CPHA266_RS03695
uniprot id: A1BED8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

290317:CPHA266 RS08495
gene id: 290317:CPHA266_RS08495
uniprot id: A1BGY4
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

290317:CPHA266 RS04260
gene id: 290317:CPHA266_RS04260
uniprot id: A1BEP4
names: Similarity
messages: Belongs to the GroES chaperonin family.

290317:CPHA266 RS10790
gene id: 290317:CPHA266_RS10790
uniprot id: A1BI59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

290317:CPHA266 RS12440
gene id: 290317:CPHA266_RS12440
uniprot id: A1BJ14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

290317:CPHA266 RS09290
gene id: 290317:CPHA266_RS09290
uniprot id: A1BHD6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

290317:CPHA266 RS04355
gene id: 290317:CPHA266_RS04355
uniprot id: A1BER1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

290317:CPHA266 RS02180
gene id: 290317:CPHA266_RS02180
uniprot id: A1BDK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

290317:CPHA266 RS09270
gene id: 290317:CPHA266_RS09270
uniprot id: A1BHD2
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

290317:CPHA266 RS12365
gene id: 290317:CPHA266_RS12365
uniprot id: A1BIZ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ChlB/BchB/BchZ family.
messages: Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
messages: Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits.

290317:CPHA266 RS10605
gene id: 290317:CPHA266_RS10605
uniprot id: A1BI29
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

290317:CPHA266 RS09195
gene id: 290317:CPHA266_RS09195
uniprot id: A1BHB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

290317:CPHA266 RS05345
gene id: 290317:CPHA266_RS05345
uniprot id: A1BF99
names: Cofactor
names: Similarity
messages: Belongs to the PdaD family.
messages: Belongs to the pyruvoyl-dependent arginine decarboxylase family.
messages: Binds 1 pyruvoyl group covalently per subunit.

290317:CPHA266 RS05255
gene id: 290317:CPHA266_RS05255
uniprot id: A1BF81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

290317:CPHA266 RS11850
gene id: 290317:CPHA266_RS11850
uniprot id: A1BIQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

290317:CPHA266 RS06805
gene id: 290317:CPHA266_RS06805
uniprot id: A1BG27
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS01225
gene id: 290317:CPHA266_RS01225
uniprot id: A1BD25
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

290317:CPHA266 RS03960
gene id: 290317:CPHA266_RS03960
uniprot id: A1BEI7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

290317:CPHA266 RS04385
gene id: 290317:CPHA266_RS04385
uniprot id: A1BER7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

290317:CPHA266 RS02015
gene id: 290317:CPHA266_RS02015
uniprot id: A1BDH3
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

290317:CPHA266 RS12135
gene id: 290317:CPHA266_RS12135
uniprot id: A1BIV6
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS03540
gene id: 290317:CPHA266_RS03540
uniprot id: A1BEA8
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

290317:CPHA266 RS02575
gene id: 290317:CPHA266_RS02575
uniprot id: A1BDS4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

290317:CPHA266 RS02670
gene id: 290317:CPHA266_RS02670
uniprot id: A1BDU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

290317:CPHA266 RS10815
gene id: 290317:CPHA266_RS10815
uniprot id: A1BI64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

290317:CPHA266 RS09330
gene id: 290317:CPHA266_RS09330
uniprot id: A1BHE4
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

290317:CPHA266 RS07060
gene id: 290317:CPHA266_RS07060
uniprot id: A1BG73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

290317:CPHA266 RS03065
gene id: 290317:CPHA266_RS03065
uniprot id: A1BE19
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS07215
gene id: 290317:CPHA266_RS07215
uniprot id: A1BGA4
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

290317:CPHA266 RS09625
gene id: 290317:CPHA266_RS09625
uniprot id: A1BHJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

290317:CPHA266 RS07825
gene id: 290317:CPHA266_RS07825
uniprot id: A1BGL3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

290317:CPHA266 RS04230
gene id: 290317:CPHA266_RS04230
uniprot id: A1BEN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

290317:CPHA266 RS02895
gene id: 290317:CPHA266_RS02895
uniprot id: A1BDY5
names: Similarity
messages: Belongs to the peptidase S49 family.

290317:CPHA266 RS06010
gene id: 290317:CPHA266_RS06010
uniprot id: A1BFM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

290317:CPHA266 RS03840
gene id: 290317:CPHA266_RS03840
uniprot id: A1BEG5
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

290317:CPHA266 RS00285
gene id: 290317:CPHA266_RS00285
uniprot id: A1BCJ9
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS05015
gene id: 290317:CPHA266_RS05015
uniprot id: A1BF33
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

290317:CPHA266 RS10225
gene id: 290317:CPHA266_RS10225
uniprot id: A1BHV4
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

290317:CPHA266 RS13370
gene id: 290317:CPHA266_RS13370
uniprot id: A1BJJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

290317:CPHA266 RS04225
gene id: 290317:CPHA266_RS04225
uniprot id: A1BEN7
names: Cofactor
names: Similarity
messages: Belongs to the PdaD family.
messages: Belongs to the pyruvoyl-dependent arginine decarboxylase family.
messages: Binds 1 pyruvoyl group covalently per subunit.

290317:CPHA266 RS06085
gene id: 290317:CPHA266_RS06085
uniprot id: A1BFN8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

290317:CPHA266 RS00720
gene id: 290317:CPHA266_RS00720
uniprot id: A1BCS9
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS02135
gene id: 290317:CPHA266_RS02135
uniprot id: A1BDJ2
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

290317:CPHA266 RS02980
gene id: 290317:CPHA266_RS02980
uniprot id: A1BE02
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

290317:CPHA266 RS04335
gene id: 290317:CPHA266_RS04335
uniprot id: A1BEQ7
names: Similarity
messages: Belongs to the UPF0047 family.

290317:CPHA266 RS12535
gene id: 290317:CPHA266_RS12535
uniprot id: A1BJ32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

290317:CPHA266 RS03710
gene id: 290317:CPHA266_RS03710
uniprot id: A1BEE1
names: Similarity
messages: Belongs to the universal stress protein A family.

290317:CPHA266 RS05565
gene id: 290317:CPHA266_RS05565
uniprot id: A1BFE0
names: Similarity
messages: Belongs to the CFA/CMAS family.

290317:CPHA266 RS12905
gene id: 290317:CPHA266_RS12905
uniprot id: A1BJA2
names: Similarity
messages: Belongs to the fabD family.

290317:CPHA266 RS13320
gene id: 290317:CPHA266_RS13320
uniprot id: A1BJI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

290317:CPHA266 RS11310
gene id: 290317:CPHA266_RS11310
uniprot id: A1BCG8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

290317:CPHA266 RS12230
gene id: 290317:CPHA266_RS12230
uniprot id: A1BIX1
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS06870
gene id: 290317:CPHA266_RS06870
uniprot id: A1BG40
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS03835
gene id: 290317:CPHA266_RS03835
uniprot id: A1BEG4
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

290317:CPHA266 RS04430
gene id: 290317:CPHA266_RS04430
uniprot id: A1BES6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

290317:CPHA266 RS01145
gene id: 290317:CPHA266_RS01145
uniprot id: A1BD13
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

290317:CPHA266 RS06105
gene id: 290317:CPHA266_RS06105
uniprot id: A1BFP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

290317:CPHA266 RS04510
gene id: 290317:CPHA266_RS04510
uniprot id: A1BEU2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

290317:CPHA266 RS13870
gene id: 290317:CPHA266_RS13870
uniprot id: A1BJT2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

290317:CPHA266 RS06245
gene id: 290317:CPHA266_RS06245
uniprot id: A1BFR5
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS04495
gene id: 290317:CPHA266_RS04495
uniprot id: A1BET9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

290317:CPHA266 RS02085
gene id: 290317:CPHA266_RS02085
uniprot id: A1BDI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

290317:CPHA266 RS12410
gene id: 290317:CPHA266_RS12410
uniprot id: A1BJ07
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

290317:CPHA266 RS00565
gene id: 290317:CPHA266_RS00565
uniprot id: A1BCP9
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

290317:CPHA266 RS02835
gene id: 290317:CPHA266_RS02835
uniprot id: A1BDX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

290317:CPHA266 RS03565
gene id: 290317:CPHA266_RS03565
uniprot id: A1BEB2
names: Similarity
messages: Belongs to the pirin family.

290317:CPHA266 RS10825
gene id: 290317:CPHA266_RS10825
uniprot id: A1BI66
names: Similarity
messages: Belongs to the UPF0235 family.

290317:CPHA266 RS10835
gene id: 290317:CPHA266_RS10835
uniprot id: A1BI68
names: Similarity
messages: Belongs to the citrate synthase family.

290317:CPHA266 RS09150
gene id: 290317:CPHA266_RS09150
uniprot id: A1BHA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

290317:CPHA266 RS00765
gene id: 290317:CPHA266_RS00765
uniprot id: A1BCT7
names: Similarity
messages: Belongs to the CmpA/NrtA family.

290317:CPHA266 RS14015
gene id: 290317:CPHA266_RS14015
uniprot id: A1BJW0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

290317:CPHA266 RS13190
gene id: 290317:CPHA266_RS13190
uniprot id: A1BJF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12) (By similarity).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

290317:CPHA266 RS12630
gene id: 290317:CPHA266_RS12630
uniprot id: A1BJ49
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS12540
gene id: 290317:CPHA266_RS12540
uniprot id: A1BJ33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

290317:CPHA266 RS11910
gene id: 290317:CPHA266_RS11910
uniprot id: A1BIR6
names: Similarity
messages: Belongs to the arsA ATPase family.

290317:CPHA266 RS03975
gene id: 290317:CPHA266_RS03975
uniprot id: A1BEJ0
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

290317:CPHA266 RS12415
gene id: 290317:CPHA266_RS12415
uniprot id: A1BJ08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

290317:CPHA266 RS08245
gene id: 290317:CPHA266_RS08245
uniprot id: A1BGU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

290317:CPHA266 RS01975
gene id: 290317:CPHA266_RS01975
uniprot id: A1BDG6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

290317:CPHA266 RS06415
gene id: 290317:CPHA266_RS06415
uniprot id: A1BFV2
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS05600
gene id: 290317:CPHA266_RS05600
uniprot id: A1BFE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

290317:CPHA266 RS00590
gene id: 290317:CPHA266_RS00590
uniprot id: A1BCQ4
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

290317:CPHA266 RS04195
gene id: 290317:CPHA266_RS04195
uniprot id: A1BEN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

290317:CPHA266 RS12665
gene id: 290317:CPHA266_RS12665
uniprot id: A1BJ56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

290317:CPHA266 RS02870
gene id: 290317:CPHA266_RS02870
uniprot id: A1BDY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

290317:CPHA266 RS02425
gene id: 290317:CPHA266_RS02425
uniprot id: A1BDP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

290317:CPHA266 RS06575
gene id: 290317:CPHA266_RS06575
uniprot id: A1BFY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

290317:CPHA266 RS04445
gene id: 290317:CPHA266_RS04445
uniprot id: A1BES9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

290317:CPHA266 RS03475
gene id: 290317:CPHA266_RS03475
uniprot id: A1BE95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

290317:CPHA266 RS02880
gene id: 290317:CPHA266_RS02880
uniprot id: A1BDY2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

290317:CPHA266 RS13330
gene id: 290317:CPHA266_RS13330
uniprot id: A1BJI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

290317:CPHA266 RS13825
gene id: 290317:CPHA266_RS13825
uniprot id: A1BJS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

290317:CPHA266 RS04960
gene id: 290317:CPHA266_RS04960
uniprot id: A1BF24
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

290317:CPHA266 RS11205
gene id: 290317:CPHA266_RS11205
uniprot id: A1BIC9
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

290317:CPHA266 RS10080
gene id: 290317:CPHA266_RS10080
uniprot id: A1BHT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

290317:CPHA266 RS12020
gene id: 290317:CPHA266_RS12020
uniprot id: A1BCG8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

290317:CPHA266 RS04175
gene id: 290317:CPHA266_RS04175
uniprot id: A1BEN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

290317:CPHA266 RS05065
gene id: 290317:CPHA266_RS05065
uniprot id: A1BF43
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

290317:CPHA266 RS06510
gene id: 290317:CPHA266_RS06510
uniprot id: A1BFX0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS12970
gene id: 290317:CPHA266_RS12970
uniprot id: A1BJB5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

290317:CPHA266 RS02935
gene id: 290317:CPHA266_RS02935
uniprot id: A1BDZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

290317:CPHA266 RS04780
gene id: 290317:CPHA266_RS04780
uniprot id: A1BEZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

290317:CPHA266 RS13175
gene id: 290317:CPHA266_RS13175
uniprot id: A1BJF2
names: Similarity
messages: Belongs to the CinA family.

290317:CPHA266 RS02235
gene id: 290317:CPHA266_RS02235
uniprot id: A1BDL1
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS03800
gene id: 290317:CPHA266_RS03800
uniprot id: A1BEF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

290317:CPHA266 RS09935
gene id: 290317:CPHA266_RS09935
uniprot id: A1BHQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

290317:CPHA266 RS05770
gene id: 290317:CPHA266_RS05770
uniprot id: A1BFI0
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

290317:CPHA266 RS09630
gene id: 290317:CPHA266_RS09630
uniprot id: A1BHJ9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

290317:CPHA266 RS00200
gene id: 290317:CPHA266_RS00200
uniprot id: A1BCI4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

290317:CPHA266 RS03770
gene id: 290317:CPHA266_RS03770
uniprot id: A1BEF1
names: Similarity
messages: Belongs to the HypD family.

290317:CPHA266 RS01200
gene id: 290317:CPHA266_RS01200
uniprot id: A1BD20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

290317:CPHA266 RS03005
gene id: 290317:CPHA266_RS03005
uniprot id: A1BE07
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

290317:CPHA266 RS07205
gene id: 290317:CPHA266_RS07205
uniprot id: A1BGA2
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

290317:CPHA266 RS01690
gene id: 290317:CPHA266_RS01690
uniprot id: A1BCG8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

290317:CPHA266 RS01890
gene id: 290317:CPHA266_RS01890
uniprot id: A1BDE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

290317:CPHA266 RS08720
gene id: 290317:CPHA266_RS08720
uniprot id: A1BH27
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS03265
gene id: 290317:CPHA266_RS03265
uniprot id: A1BE56
names: Similarity
messages: Belongs to the glutamate synthase family.

290317:CPHA266 RS11255
gene id: 290317:CPHA266_RS11255
uniprot id: A1BID9
names: Similarity
messages: Belongs to the universal stress protein A family.

290317:CPHA266 RS04155
gene id: 290317:CPHA266_RS04155
uniprot id: A1BEM7
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

290317:CPHA266 RS02755
gene id: 290317:CPHA266_RS02755
uniprot id: A1BDV8
names: Similarity
messages: Belongs to the GARS family.

290317:CPHA266 RS14150
gene id: 290317:CPHA266_RS14150
uniprot id: A1BJY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

290317:CPHA266 RS02365
gene id: 290317:CPHA266_RS02365
uniprot id: A1BDN6
names: Similarity
messages: Belongs to the NadC/ModD family.

290317:CPHA266 RS02210
gene id: 290317:CPHA266_RS02210
uniprot id: A1BDK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

290317:CPHA266 RS07425
gene id: 290317:CPHA266_RS07425
uniprot id: A1BGE2
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

290317:CPHA266 RS16025
gene id: 290317:CPHA266_RS16025
uniprot id: A1BHH9
names: Similarity
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.

290317:CPHA266 RS00170
gene id: 290317:CPHA266_RS00170
uniprot id: A1BCH9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

290317:CPHA266 RS02875
gene id: 290317:CPHA266_RS02875
uniprot id: A1BDY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

290317:CPHA266 RS01265
gene id: 290317:CPHA266_RS01265
uniprot id: A1BD33
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

290317:CPHA266 RS05955
gene id: 290317:CPHA266_RS05955
uniprot id: A1BFL6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

290317:CPHA266 RS10535
gene id: 290317:CPHA266_RS10535
uniprot id: A1BI15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

290317:CPHA266 RS04215
gene id: 290317:CPHA266_RS04215
uniprot id: A1BEN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

290317:CPHA266 RS01415
gene id: 290317:CPHA266_RS01415
uniprot id: A1BCG8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

290317:CPHA266 RS07795
gene id: 290317:CPHA266_RS07795
uniprot id: A1BGK7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

290317:CPHA266 RS05210
gene id: 290317:CPHA266_RS05210
uniprot id: A1BF73
names: Similarity
messages: Belongs to the UPF0251 family.

290317:CPHA266 RS11795
gene id: 290317:CPHA266_RS11795
uniprot id: A1BIP3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

290317:CPHA266 RS03510
gene id: 290317:CPHA266_RS03510
uniprot id: A1BEA2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

290317:CPHA266 RS14110
gene id: 290317:CPHA266_RS14110
uniprot id: A1BJX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

290317:CPHA266 RS05660
gene id: 290317:CPHA266_RS05660
uniprot id: A1BFF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

290317:CPHA266 RS09850
gene id: 290317:CPHA266_RS09850
uniprot id: A1BHN9
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

290317:CPHA266 RS03140
gene id: 290317:CPHA266_RS03140
uniprot id: A1BE32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

290317:CPHA266 RS04145
gene id: 290317:CPHA266_RS04145
uniprot id: A1BEM5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

290317:CPHA266 RS13900
gene id: 290317:CPHA266_RS13900
uniprot id: A1BJT7
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

290317:CPHA266 RS07490
gene id: 290317:CPHA266_RS07490
uniprot id: A1BGF5
names: Similarity
messages: Belongs to the LOG family.

290317:CPHA266 RS00130
gene id: 290317:CPHA266_RS00130
uniprot id: A1BCG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

290317:CPHA266 RS09715
gene id: 290317:CPHA266_RS09715
uniprot id: A1BHL6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

290317:CPHA266 RS08445
gene id: 290317:CPHA266_RS08445
uniprot id: A1BGX4
names: Function
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.
messages: Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.

290317:CPHA266 RS12245
gene id: 290317:CPHA266_RS12245
uniprot id: A1BIX4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

290317:CPHA266 RS12425
gene id: 290317:CPHA266_RS12425
uniprot id: A1BJ10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

290317:CPHA266 RS03025
gene id: 290317:CPHA266_RS03025
uniprot id: A1BE11
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

290317:CPHA266 RS04360
gene id: 290317:CPHA266_RS04360
uniprot id: A1BER2
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

290317:CPHA266 RS10775
gene id: 290317:CPHA266_RS10775
uniprot id: A1BI56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

290317:CPHA266 RS08055
gene id: 290317:CPHA266_RS08055
uniprot id: A1BGQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

290317:CPHA266 RS14125
gene id: 290317:CPHA266_RS14125
uniprot id: A1BJY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

290317:CPHA266 RS05625
gene id: 290317:CPHA266_RS05625
uniprot id: A1BFF2
names: Similarity
messages: Belongs to the arsA ATPase family.

290317:CPHA266 RS00505
gene id: 290317:CPHA266_RS00505
uniprot id: A1BCN7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

290317:CPHA266 RS08585
gene id: 290317:CPHA266_RS08585
uniprot id: A1BH00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

290317:CPHA266 RS03130
gene id: 290317:CPHA266_RS03130
uniprot id: A1BE30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

290317:CPHA266 RS03660
gene id: 290317:CPHA266_RS03660
uniprot id: A1BED1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

290317:CPHA266 RS00255
gene id: 290317:CPHA266_RS00255
uniprot id: A1BCJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

290317:CPHA266 RS10290
gene id: 290317:CPHA266_RS10290
uniprot id: A1BHW7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

290317:CPHA266 RS05060
gene id: 290317:CPHA266_RS05060
uniprot id: A1BF42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

290317:CPHA266 RS12420
gene id: 290317:CPHA266_RS12420
uniprot id: A1BJ09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

290317:CPHA266 RS11950
gene id: 290317:CPHA266_RS11950
uniprot id: A1BCG8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

290317:CPHA266 RS02770
gene id: 290317:CPHA266_RS02770
uniprot id: A1BDW1
names: Similarity
messages: Belongs to the TrpC family.

290317:CPHA266 RS03350
gene id: 290317:CPHA266_RS03350
uniprot id: A1BE72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

290317:CPHA266 RS01650
gene id: 290317:CPHA266_RS01650
uniprot id: A1BDA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

290317:CPHA266 RS10780
gene id: 290317:CPHA266_RS10780
uniprot id: A1BI57
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

290317:CPHA266 RS09275
gene id: 290317:CPHA266_RS09275
uniprot id: A1BHD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

290317:CPHA266 RS09110
gene id: 290317:CPHA266_RS09110
uniprot id: A1BHA1
names: Similarity
messages: Belongs to the UPF0758 family.

290317:CPHA266 RS02810
gene id: 290317:CPHA266_RS02810
uniprot id: A1BDW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

290317:CPHA266 RS13005
gene id: 290317:CPHA266_RS13005
uniprot id: A1BJC2
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS01070
gene id: 290317:CPHA266_RS01070
uniprot id: A1BCZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

290317:CPHA266 RS12675
gene id: 290317:CPHA266_RS12675
uniprot id: A1BJ58
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

290317:CPHA266 RS01540
gene id: 290317:CPHA266_RS01540
uniprot id: A1BD85
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

290317:CPHA266 RS03225
gene id: 290317:CPHA266_RS03225
uniprot id: A1BE48
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

290317:CPHA266 RS02125
gene id: 290317:CPHA266_RS02125
uniprot id: A1BDJ0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

290317:CPHA266 RS13380
gene id: 290317:CPHA266_RS13380
uniprot id: A1BJJ4
names: Similarity
messages: Belongs to the aspartokinase family.

290317:CPHA266 RS10375
gene id: 290317:CPHA266_RS10375
uniprot id: A1BHY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

290317:CPHA266 RS04920
gene id: 290317:CPHA266_RS04920
uniprot id: A1BF16
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS10370
gene id: 290317:CPHA266_RS10370
uniprot id: A1BHY2
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

290317:CPHA266 RS14185
gene id: 290317:CPHA266_RS14185
uniprot id: A1BJZ3
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS10200
gene id: 290317:CPHA266_RS10200
uniprot id: A1BHV1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

290317:CPHA266 RS00125
gene id: 290317:CPHA266_RS00125
uniprot id: A1BCF4
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

290317:CPHA266 RS13800
gene id: 290317:CPHA266_RS13800
uniprot id: A1BJR8
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

290317:CPHA266 RS10915
gene id: 290317:CPHA266_RS10915
uniprot id: A1BI83
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

290317:CPHA266 RS12775
gene id: 290317:CPHA266_RS12775
uniprot id: A1BJ77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

290317:CPHA266 RS03650
gene id: 290317:CPHA266_RS03650
uniprot id: A1BEC9
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

290317:CPHA266 RS03595
gene id: 290317:CPHA266_RS03595
uniprot id: A1BEB8
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS01730
gene id: 290317:CPHA266_RS01730
uniprot id: A1BDB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

290317:CPHA266 RS10215
gene id: 290317:CPHA266_RS10215
uniprot id: A1BHV2
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

290317:CPHA266 RS09900
gene id: 290317:CPHA266_RS09900
uniprot id: A1BHP9
names: Similarity
messages: Belongs to the CIA30 family.

290317:CPHA266 RS10495
gene id: 290317:CPHA266_RS10495
uniprot id: A1BI07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

290317:CPHA266 RS09800
gene id: 290317:CPHA266_RS09800
uniprot id: A1BHM9
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS09590
gene id: 290317:CPHA266_RS09590
uniprot id: A1BHJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

290317:CPHA266 RS13000
gene id: 290317:CPHA266_RS13000
uniprot id: A1BJC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

290317:CPHA266 RS07510
gene id: 290317:CPHA266_RS07510
uniprot id: A1BGF9
names: Similarity
messages: Belongs to the UPF0251 family.

290317:CPHA266 RS02535
gene id: 290317:CPHA266_RS02535
uniprot id: A1BDR6
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS02920
gene id: 290317:CPHA266_RS02920
uniprot id: A1BDZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

290317:CPHA266 RS02960
gene id: 290317:CPHA266_RS02960
uniprot id: A1BDZ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

290317:CPHA266 RS07920
gene id: 290317:CPHA266_RS07920
uniprot id: A1BGN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

290317:CPHA266 RS04470
gene id: 290317:CPHA266_RS04470
uniprot id: A1BET4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

290317:CPHA266 RS05635
gene id: 290317:CPHA266_RS05635
uniprot id: A1BFF4
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

290317:CPHA266 RS09655
gene id: 290317:CPHA266_RS09655
uniprot id: A1BHK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

290317:CPHA266 RS09065
gene id: 290317:CPHA266_RS09065
uniprot id: A1BCG8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

290317:CPHA266 RS06395
gene id: 290317:CPHA266_RS06395
uniprot id: A1BFU7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

290317:CPHA266 RS03365
gene id: 290317:CPHA266_RS03365
uniprot id: A1BE75
names: Similarity
messages: Belongs to the UPF0175 family.

290317:CPHA266 RS12550
gene id: 290317:CPHA266_RS12550
uniprot id: A1BJ35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

290317:CPHA266 RS00935
gene id: 290317:CPHA266_RS00935
uniprot id: A1BCW9
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

290317:CPHA266 RS04840
gene id: 290317:CPHA266_RS04840
uniprot id: A1BF00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

290317:CPHA266 RS06905
gene id: 290317:CPHA266_RS06905
uniprot id: A1BG47
names: Caution
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS12895
gene id: 290317:CPHA266_RS12895
uniprot id: A1BJA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

290317:CPHA266 RS03495
gene id: 290317:CPHA266_RS03495
uniprot id: A1BE99
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

290317:CPHA266 RS08435
gene id: 290317:CPHA266_RS08435
uniprot id: A1BGX2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

290317:CPHA266 RS00235
gene id: 290317:CPHA266_RS00235
uniprot id: A1BCJ1
names: Similarity
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

290317:CPHA266 RS04255
gene id: 290317:CPHA266_RS04255
uniprot id: A1BEP3
names: Similarity
messages: Belongs to the MreC family.

290317:CPHA266 RS10365
gene id: 290317:CPHA266_RS10365
uniprot id: A1BHY1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

290317:CPHA266 RS00900
gene id: 290317:CPHA266_RS00900
uniprot id: A1BCW2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

290317:CPHA266 RS13765
gene id: 290317:CPHA266_RS13765
uniprot id: A1BCG8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

290317:CPHA266 RS01115
gene id: 290317:CPHA266_RS01115
uniprot id: A1BD07
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

290317:CPHA266 RS10295
gene id: 290317:CPHA266_RS10295
uniprot id: A1BHW8
names: Similarity
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.

290317:CPHA266 RS11720
gene id: 290317:CPHA266_RS11720
uniprot id: A1BIN1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

290317:CPHA266 RS03665
gene id: 290317:CPHA266_RS03665
uniprot id: A1BED2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

290317:CPHA266 RS12510
gene id: 290317:CPHA266_RS12510
uniprot id: A1BJ27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

290317:CPHA266 RS00425
gene id: 290317:CPHA266_RS00425
uniprot id: A1BCM3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

290317:CPHA266 RS12280
gene id: 290317:CPHA266_RS12280
uniprot id: A1BIY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

290317:CPHA266 RS05205
gene id: 290317:CPHA266_RS05205
uniprot id: A1BF72
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS02545
gene id: 290317:CPHA266_RS02545
uniprot id: A1BDR8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

290317:CPHA266 RS09960
gene id: 290317:CPHA266_RS09960
uniprot id: A1BHR1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell inner membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

290317:CPHA266 RS13210
gene id: 290317:CPHA266_RS13210
uniprot id: A1BJF9
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

290317:CPHA266 RS00515
gene id: 290317:CPHA266_RS00515
uniprot id: A1BCN9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

290317:CPHA266 RS00120
gene id: 290317:CPHA266_RS00120
uniprot id: A1BCF3
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

290317:CPHA266 RS10445
gene id: 290317:CPHA266_RS10445
uniprot id: A1BHZ6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

290317:CPHA266 RS00180
gene id: 290317:CPHA266_RS00180
uniprot id: A1BCI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

290317:CPHA266 RS07855
gene id: 290317:CPHA266_RS07855
uniprot id: A1BGL9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

290317:CPHA266 RS13530
gene id: 290317:CPHA266_RS13530
uniprot id: A1BJM1
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

290317:CPHA266 RS08485
gene id: 290317:CPHA266_RS08485
uniprot id: A1BGY2
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

290317:CPHA266 RS05835
gene id: 290317:CPHA266_RS05835
uniprot id: A1BFJ4
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

290317:CPHA266 RS05820
gene id: 290317:CPHA266_RS05820
uniprot id: A1BFJ1
names: Similarity
messages: Belongs to the HsdR family.

290317:CPHA266 RS12740
gene id: 290317:CPHA266_RS12740
uniprot id: A1BJ70
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

290317:CPHA266 RS13015
gene id: 290317:CPHA266_RS13015
uniprot id: A1BJC4
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

290317:CPHA266 RS03145
gene id: 290317:CPHA266_RS03145
uniprot id: A1BE33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

290317:CPHA266 RS07210
gene id: 290317:CPHA266_RS07210
uniprot id: A1BGA3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

290317:CPHA266 RS03775
gene id: 290317:CPHA266_RS03775
uniprot id: A1BEF2
names: Similarity
messages: Belongs to the HypE family.

290317:CPHA266 RS01235
gene id: 290317:CPHA266_RS01235
uniprot id: A1BD27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

290317:CPHA266 RS14210
gene id: 290317:CPHA266_RS14210
uniprot id: A1BJZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

290317:CPHA266 RS01765
gene id: 290317:CPHA266_RS01765
uniprot id: A1BDC6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS07105
gene id: 290317:CPHA266_RS07105
uniprot id: A1BG82
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

290317:CPHA266 RS13205
gene id: 290317:CPHA266_RS13205
uniprot id: A1BJF8
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

290317:CPHA266 RS01555
gene id: 290317:CPHA266_RS01555
uniprot id: A1BD88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

290317:CPHA266 RS10345
gene id: 290317:CPHA266_RS10345
uniprot id: A1BHX7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

290317:CPHA266 RS06025
gene id: 290317:CPHA266_RS06025
uniprot id: A1BFM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

290317:CPHA266 RS04695
gene id: 290317:CPHA266_RS04695
uniprot id: A1BEX7
names: Similarity
messages: Belongs to the AlaDH/PNT family.

290317:CPHA266 RS09845
gene id: 290317:CPHA266_RS09845
uniprot id: A1BHN8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

290317:CPHA266 RS08060
gene id: 290317:CPHA266_RS08060
uniprot id: A1BGQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

290317:CPHA266 RS13385
gene id: 290317:CPHA266_RS13385
uniprot id: A1BJJ5
names: Similarity
messages: Belongs to the peptidase C40 family.

290317:CPHA266 RS04435
gene id: 290317:CPHA266_RS04435
uniprot id: A1BES7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

290317:CPHA266 RS08020
gene id: 290317:CPHA266_RS08020
uniprot id: A1BCG8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

290317:CPHA266 RS09740
gene id: 290317:CPHA266_RS09740
uniprot id: A1BHM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

290317:CPHA266 RS14040
gene id: 290317:CPHA266_RS14040
uniprot id: A1BJW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has four main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains (By similarity).

290317:CPHA266 RS11235
gene id: 290317:CPHA266_RS11235
uniprot id: A1BID5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS11825
gene id: 290317:CPHA266_RS11825
uniprot id: A1BIP9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

290317:CPHA266 RS13195
gene id: 290317:CPHA266_RS13195
uniprot id: A1BJF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

290317:CPHA266 RS12595
gene id: 290317:CPHA266_RS12595
uniprot id: A1BJ44
names: Similarity
messages: Belongs to the peptidase S1 family.

290317:CPHA266 RS05980
gene id: 290317:CPHA266_RS05980
uniprot id: A1BFM0
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS05175
gene id: 290317:CPHA266_RS05175
uniprot id: A1BF66
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

290317:CPHA266 RS02560
gene id: 290317:CPHA266_RS02560
uniprot id: A1BDS1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

290317:CPHA266 RS03035
gene id: 290317:CPHA266_RS03035
uniprot id: A1BE13
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

290317:CPHA266 RS08595
gene id: 290317:CPHA266_RS08595
uniprot id: A1BH02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

290317:CPHA266 RS01875
gene id: 290317:CPHA266_RS01875
uniprot id: A1BDE6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

290317:CPHA266 RS13720
gene id: 290317:CPHA266_RS13720
uniprot id: A1BJQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

290317:CPHA266 RS04765
gene id: 290317:CPHA266_RS04765
uniprot id: A1BEZ1
names: Similarity
messages: Belongs to the TrpF family.

290317:CPHA266 RS01075
gene id: 290317:CPHA266_RS01075
uniprot id: A1BCZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BChl C/E-binding protein family.
messages: Component of the photosynthetic apparatus.
messages: chlorosome envelope

290317:CPHA266 RS13215
gene id: 290317:CPHA266_RS13215
uniprot id: A1BJG0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

290317:CPHA266 RS13520
gene id: 290317:CPHA266_RS13520
uniprot id: A1BJL9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290317:CPHA266 RS11965
gene id: 290317:CPHA266_RS11965
uniprot id: A1BIS5
names: Similarity
messages: Belongs to the Mg-chelatase subunit H family.

290317:CPHA266 RS00220
gene id: 290317:CPHA266_RS00220
uniprot id: A1BCI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

290317:CPHA266 RS10935
gene id: 290317:CPHA266_RS10935
uniprot id: A1BI87
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

290317:CPHA266 RS11730
gene id: 290317:CPHA266_RS11730
uniprot id: A1BIN2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

290317:CPHA266 RS03585
gene id: 290317:CPHA266_RS03585
uniprot id: A1BEB6
names: Subcellular Location Annotation
messages: Membrane

290317:CPHA266 RS14050
gene id: 290317:CPHA266_RS14050
uniprot id: A1BJW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a, b, b' and c.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

290317:CPHA266 RS05155
gene id: 290317:CPHA266_RS05155
uniprot id: A1BF62
names: Subcellular Location Annotation
messages: Membrane