290315:CLIM RS01770
gene id: 290315:CLIM_RS01770
uniprot id: B3EFF1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

290315:CLIM RS07615
gene id: 290315:CLIM_RS07615
uniprot id: B3EDE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

290315:CLIM RS03055
gene id: 290315:CLIM_RS03055
uniprot id: B3EH07
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

290315:CLIM RS11870
gene id: 290315:CLIM_RS11870
uniprot id: B3EHX8
names: Similarity
messages: Belongs to the arsA ATPase family.

290315:CLIM RS04830
gene id: 290315:CLIM_RS04830
uniprot id: B3EIU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

290315:CLIM RS05575
gene id: 290315:CLIM_RS05575
uniprot id: B3ECB1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

290315:CLIM RS07035
gene id: 290315:CLIM_RS07035
uniprot id: B3ED43
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

290315:CLIM RS03045
gene id: 290315:CLIM_RS03045
uniprot id: B3EH05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

290315:CLIM RS10900
gene id: 290315:CLIM_RS10900
uniprot id: B3EGT0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

290315:CLIM RS03525
gene id: 290315:CLIM_RS03525
uniprot id: B3EHK3
names: Similarity
messages: Belongs to the DsrF/TusC family.

290315:CLIM RS09785
gene id: 290315:CLIM_RS09785
uniprot id: B3EFL6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

290315:CLIM RS08535
gene id: 290315:CLIM_RS08535
uniprot id: B3EE34
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

290315:CLIM RS02220
gene id: 290315:CLIM_RS02220
uniprot id: B3EFZ2
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS01795
gene id: 290315:CLIM_RS01795
uniprot id: B3EFF6
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

290315:CLIM RS11895
gene id: 290315:CLIM_RS11895
uniprot id: B3EHY3
names: Similarity
messages: Belongs to the LOG family.

290315:CLIM RS11170
gene id: 290315:CLIM_RS11170
uniprot id: B3EGY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

290315:CLIM RS11070
gene id: 290315:CLIM_RS11070
uniprot id: B3EGW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

290315:CLIM RS11735
gene id: 290315:CLIM_RS11735
uniprot id: B3EHV1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

290315:CLIM RS02700
gene id: 290315:CLIM_RS02700
uniprot id: B3EGI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

290315:CLIM RS04755
gene id: 290315:CLIM_RS04755
uniprot id: B3EIT0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS08200
gene id: 290315:CLIM_RS08200
uniprot id: B3EDX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

290315:CLIM RS04930
gene id: 290315:CLIM_RS04930
uniprot id: B3EIW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

290315:CLIM RS02460
gene id: 290315:CLIM_RS02460
uniprot id: B3EGD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

290315:CLIM RS04955
gene id: 290315:CLIM_RS04955
uniprot id: B3EIX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

290315:CLIM RS11690
gene id: 290315:CLIM_RS11690
uniprot id: B3EHI9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

290315:CLIM RS11540
gene id: 290315:CLIM_RS11540
uniprot id: B3EHF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

290315:CLIM RS04810
gene id: 290315:CLIM_RS04810
uniprot id: B3EIU2
names: Similarity
messages: Belongs to the CFA/CMAS family.

290315:CLIM RS07130
gene id: 290315:CLIM_RS07130
uniprot id: B3ED62
names: Similarity
messages: Belongs to the UPF0251 family.

290315:CLIM RS04240
gene id: 290315:CLIM_RS04240
uniprot id: B3EI93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

290315:CLIM RS06365
gene id: 290315:CLIM_RS06365
uniprot id: B3ECR4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

290315:CLIM RS05855
gene id: 290315:CLIM_RS05855
uniprot id: B3ECG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

290315:CLIM RS04900
gene id: 290315:CLIM_RS04900
uniprot id: B3EIW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

290315:CLIM RS06245
gene id: 290315:CLIM_RS06245
uniprot id: B3ECP0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS06805
gene id: 290315:CLIM_RS06805
uniprot id: B3ECZ9
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

290315:CLIM RS11945
gene id: 290315:CLIM_RS11945
uniprot id: B3EHZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

290315:CLIM RS10765
gene id: 290315:CLIM_RS10765
uniprot id: B3EGQ4
names: Similarity
messages: Belongs to the arsA ATPase family.

290315:CLIM RS05760
gene id: 290315:CLIM_RS05760
uniprot id: B3ECE7
names: Similarity
messages: Belongs to the LOG family.

290315:CLIM RS07065
gene id: 290315:CLIM_RS07065
uniprot id: B3ED49
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

290315:CLIM RS01910
gene id: 290315:CLIM_RS01910
uniprot id: B3EFH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

290315:CLIM RS12010
gene id: 290315:CLIM_RS12010
uniprot id: B3EI07
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

290315:CLIM RS03475
gene id: 290315:CLIM_RS03475
uniprot id: B3EHJ3
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

290315:CLIM RS04275
gene id: 290315:CLIM_RS04275
uniprot id: B3EIA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

290315:CLIM RS08480
gene id: 290315:CLIM_RS08480
uniprot id: B3EE23
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS10015
gene id: 290315:CLIM_RS10015
uniprot id: B3EFR0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

290315:CLIM RS08625
gene id: 290315:CLIM_RS08625
uniprot id: B3EEE4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

290315:CLIM RS11215
gene id: 290315:CLIM_RS11215
uniprot id: B3EH94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

290315:CLIM RS02635
gene id: 290315:CLIM_RS02635
uniprot id: B3EGH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

290315:CLIM RS11800
gene id: 290315:CLIM_RS11800
uniprot id: B3EHW4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

290315:CLIM RS11620
gene id: 290315:CLIM_RS11620
uniprot id: B3EHH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

290315:CLIM RS07075
gene id: 290315:CLIM_RS07075
uniprot id: B3ED51
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

290315:CLIM RS02115
gene id: 290315:CLIM_RS02115
uniprot id: B3EFX1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

290315:CLIM RS11880
gene id: 290315:CLIM_RS11880
uniprot id: B3EHY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

290315:CLIM RS07640
gene id: 290315:CLIM_RS07640
uniprot id: B3EDE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

290315:CLIM RS04920
gene id: 290315:CLIM_RS04920
uniprot id: B3EIW4
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS03805
gene id: 290315:CLIM_RS03805
uniprot id: B3EHQ8
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

290315:CLIM RS01935
gene id: 290315:CLIM_RS01935
uniprot id: B3EFI5
names: Similarity
messages: Belongs to the NadC/ModD family.

290315:CLIM RS11090
gene id: 290315:CLIM_RS11090
uniprot id: B3EGW9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

290315:CLIM RS11105
gene id: 290315:CLIM_RS11105
uniprot id: B3EGX2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

290315:CLIM RS01065
gene id: 290315:CLIM_RS01065
uniprot id: B3EER4
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

290315:CLIM RS00655
gene id: 290315:CLIM_RS00655
uniprot id: B3EE94
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

290315:CLIM RS01400
gene id: 290315:CLIM_RS01400
uniprot id: B3EEX9
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS06545
gene id: 290315:CLIM_RS06545
uniprot id: B3ECU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

290315:CLIM RS00860
gene id: 290315:CLIM_RS00860
uniprot id: B3EEC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

290315:CLIM RS00865
gene id: 290315:CLIM_RS00865
uniprot id: B3EED0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

290315:CLIM RS06265
gene id: 290315:CLIM_RS06265
uniprot id: B3ECP4
names: Similarity
messages: Belongs to the peptidase S41A family.

290315:CLIM RS05595
gene id: 290315:CLIM_RS05595
uniprot id: B3ECB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

290315:CLIM RS07495
gene id: 290315:CLIM_RS07495
uniprot id: B3EDC5
names: Similarity
messages: Belongs to the peptidase S9A family.

290315:CLIM RS05030
gene id: 290315:CLIM_RS05030
uniprot id: B3EC02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

290315:CLIM RS11165
gene id: 290315:CLIM_RS11165
uniprot id: B3EGY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

290315:CLIM RS01555
gene id: 290315:CLIM_RS01555
uniprot id: B3EFB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

290315:CLIM RS12795
gene id: 290315:CLIM_RS12795
uniprot id: B3EG98
names: Subcellular Location Annotation
messages: Cell inner membrane

290315:CLIM RS00205
gene id: 290315:CLIM_RS00205
uniprot id: B3EDR9
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

290315:CLIM RS01060
gene id: 290315:CLIM_RS01060
uniprot id: B3EER3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

290315:CLIM RS04905
gene id: 290315:CLIM_RS04905
uniprot id: B3EIW1
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

290315:CLIM RS02875
gene id: 290315:CLIM_RS02875
uniprot id: B3EGL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

290315:CLIM RS03110
gene id: 290315:CLIM_RS03110
uniprot id: B3EH18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

290315:CLIM RS04430
gene id: 290315:CLIM_RS04430
uniprot id: B3EIC9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

290315:CLIM RS12430
gene id: 290315:CLIM_RS12430
uniprot id: B3EII7
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

290315:CLIM RS11175
gene id: 290315:CLIM_RS11175
uniprot id: B3EGY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

290315:CLIM RS09145
gene id: 290315:CLIM_RS09145
uniprot id: B3EEZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

290315:CLIM RS10920
gene id: 290315:CLIM_RS10920
uniprot id: B3EGT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

290315:CLIM RS08455
gene id: 290315:CLIM_RS08455
uniprot id: B3EE17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

290315:CLIM RS11250
gene id: 290315:CLIM_RS11250
uniprot id: B3EHA1
names: Similarity
messages: Belongs to the YjdM family.

290315:CLIM RS08595
gene id: 290315:CLIM_RS08595
uniprot id: B3EE46
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS04280
gene id: 290315:CLIM_RS04280
uniprot id: B3EIA1
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS10500
gene id: 290315:CLIM_RS10500
uniprot id: B3EGA6
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS12585
gene id: 290315:CLIM_RS12585
uniprot id: B3EIL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

290315:CLIM RS02315
gene id: 290315:CLIM_RS02315
uniprot id: B3EG12
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS00345
gene id: 290315:CLIM_RS00345
uniprot id: B3EDU5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

290315:CLIM RS08945
gene id: 290315:CLIM_RS08945
uniprot id: B3EEK4
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

290315:CLIM RS08410
gene id: 290315:CLIM_RS08410
uniprot id: B3EE08
names: Similarity
messages: Belongs to the PucC family.

290315:CLIM RS12130
gene id: 290315:CLIM_RS12130
uniprot id: B3EI31
names: Similarity
messages: Belongs to the aspartokinase family.

290315:CLIM RS07650
gene id: 290315:CLIM_RS07650
uniprot id: B3EDF1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

290315:CLIM RS11130
gene id: 290315:CLIM_RS11130
uniprot id: B3EGX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

290315:CLIM RS11030
gene id: 290315:CLIM_RS11030
uniprot id: B3EGV6
names: Similarity
messages: Belongs to the UPF0045 family.

290315:CLIM RS01980
gene id: 290315:CLIM_RS01980
uniprot id: B3EFU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

290315:CLIM RS08890
gene id: 290315:CLIM_RS08890
uniprot id: B3EEJ4
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS08500
gene id: 290315:CLIM_RS08500
uniprot id: B3EE27
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

290315:CLIM RS08910
gene id: 290315:CLIM_RS08910
uniprot id: B3EEJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

290315:CLIM RS03335
gene id: 290315:CLIM_RS03335
uniprot id: B3EH65
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS10845
gene id: 290315:CLIM_RS10845
uniprot id: B3EGS0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

290315:CLIM RS04820
gene id: 290315:CLIM_RS04820
uniprot id: B3EIU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

290315:CLIM RS07080
gene id: 290315:CLIM_RS07080
uniprot id: B3ED52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

290315:CLIM RS04785
gene id: 290315:CLIM_RS04785
uniprot id: B3EIT6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

290315:CLIM RS08725
gene id: 290315:CLIM_RS08725
uniprot id: B3EEG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

290315:CLIM RS01810
gene id: 290315:CLIM_RS01810
uniprot id: B3EFF9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

290315:CLIM RS02785
gene id: 290315:CLIM_RS02785
uniprot id: B3EGJ9
names: Similarity
messages: Belongs to the DEAD box helicase family.

290315:CLIM RS08740
gene id: 290315:CLIM_RS08740
uniprot id: B3EEG5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

290315:CLIM RS12570
gene id: 290315:CLIM_RS12570
uniprot id: B3EIL3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS03765
gene id: 290315:CLIM_RS03765
uniprot id: B3EHQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

290315:CLIM RS00415
gene id: 290315:CLIM_RS00415
uniprot id: B3EE55
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

290315:CLIM RS02835
gene id: 290315:CLIM_RS02835
uniprot id: B3EGL0
names: Similarity
messages: Belongs to the pirin family.

290315:CLIM RS12445
gene id: 290315:CLIM_RS12445
uniprot id: B3EIJ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

290315:CLIM RS11180
gene id: 290315:CLIM_RS11180
uniprot id: B3EGY6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

290315:CLIM RS05135
gene id: 290315:CLIM_RS05135
uniprot id: B3EC21
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

290315:CLIM RS02815
gene id: 290315:CLIM_RS02815
uniprot id: B3EGK6
names: Similarity
messages: Belongs to the arsA ATPase family.

290315:CLIM RS10355
gene id: 290315:CLIM_RS10355
uniprot id: B3EG78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

290315:CLIM RS09055
gene id: 290315:CLIM_RS09055
uniprot id: B3EEM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

290315:CLIM RS12755
gene id: 290315:CLIM_RS12755
uniprot id: B3EDI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

290315:CLIM RS12230
gene id: 290315:CLIM_RS12230
uniprot id: B3EIE8
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS08660
gene id: 290315:CLIM_RS08660
uniprot id: B3EEF0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

290315:CLIM RS12190
gene id: 290315:CLIM_RS12190
uniprot id: B3EI43
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

290315:CLIM RS09530
gene id: 290315:CLIM_RS09530
uniprot id: B3EF68
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

290315:CLIM RS00425
gene id: 290315:CLIM_RS00425
uniprot id: B3EE57
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

290315:CLIM RS06655
gene id: 290315:CLIM_RS06655
uniprot id: B3ECW9
names: Similarity
messages: Belongs to the peptidase M1 family.

290315:CLIM RS02170
gene id: 290315:CLIM_RS02170
uniprot id: B3EFY3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

290315:CLIM RS01830
gene id: 290315:CLIM_RS01830
uniprot id: B3EFG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

290315:CLIM RS12165
gene id: 290315:CLIM_RS12165
uniprot id: B3EI38
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS01640
gene id: 290315:CLIM_RS01640
uniprot id: B3EFC9
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS09080
gene id: 290315:CLIM_RS09080
uniprot id: B3EEN1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

290315:CLIM RS05160
gene id: 290315:CLIM_RS05160
uniprot id: B3EC25
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

290315:CLIM RS04510
gene id: 290315:CLIM_RS04510
uniprot id: B3EIN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

290315:CLIM RS11195
gene id: 290315:CLIM_RS11195
uniprot id: B3EGY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

290315:CLIM RS08695
gene id: 290315:CLIM_RS08695
uniprot id: B3EEF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

290315:CLIM RS01745
gene id: 290315:CLIM_RS01745
uniprot id: B3EFE6
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS00855
gene id: 290315:CLIM_RS00855
uniprot id: B3EEC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

290315:CLIM RS04260
gene id: 290315:CLIM_RS04260
uniprot id: B3EI97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

290315:CLIM RS00520
gene id: 290315:CLIM_RS00520
uniprot id: B3EE75
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

290315:CLIM RS08985
gene id: 290315:CLIM_RS08985
uniprot id: B3EEL2
names: Similarity
messages: Belongs to the HypD family.

290315:CLIM RS04190
gene id: 290315:CLIM_RS04190
uniprot id: B3EI85
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

290315:CLIM RS04850
gene id: 290315:CLIM_RS04850
uniprot id: B3EIV0
names: Similarity
messages: Belongs to the transglycosylase Slt family.

290315:CLIM RS05755
gene id: 290315:CLIM_RS05755
uniprot id: B3ECE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell inner membrane
messages: Mediates zinc uptake. May also transport other divalent cations.

290315:CLIM RS12185
gene id: 290315:CLIM_RS12185
uniprot id: B3EI42
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

290315:CLIM RS03685
gene id: 290315:CLIM_RS03685
uniprot id: B3EHN5
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

290315:CLIM RS09100
gene id: 290315:CLIM_RS09100
uniprot id: B3EEN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

290315:CLIM RS11125
gene id: 290315:CLIM_RS11125
uniprot id: B3EGX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

290315:CLIM RS06030
gene id: 290315:CLIM_RS06030
uniprot id: B3ECJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

290315:CLIM RS00315
gene id: 290315:CLIM_RS00315
uniprot id: B3EDT8
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS06585
gene id: 290315:CLIM_RS06585
uniprot id: B3ECV7
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

290315:CLIM RS01565
gene id: 290315:CLIM_RS01565
uniprot id: B3EFB4
names: Similarity
messages: Belongs to the ribF family.

290315:CLIM RS02510
gene id: 290315:CLIM_RS02510
uniprot id: B3EGE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

290315:CLIM RS05750
gene id: 290315:CLIM_RS05750
uniprot id: B3ECE5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell inner membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

290315:CLIM RS12080
gene id: 290315:CLIM_RS12080
uniprot id: B3EI21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

290315:CLIM RS03220
gene id: 290315:CLIM_RS03220
uniprot id: B3EH40
names: Similarity
messages: Belongs to the CutA family.

290315:CLIM RS08680
gene id: 290315:CLIM_RS08680
uniprot id: B3EEF3
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS11715
gene id: 290315:CLIM_RS11715
uniprot id: B3EHU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

290315:CLIM RS10005
gene id: 290315:CLIM_RS10005
uniprot id: B3EFQ8
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

290315:CLIM RS00885
gene id: 290315:CLIM_RS00885
uniprot id: B3EED4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

290315:CLIM RS08925
gene id: 290315:CLIM_RS08925
uniprot id: B3EEK0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

290315:CLIM RS04375
gene id: 290315:CLIM_RS04375
uniprot id: B3EIC0
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

290315:CLIM RS00440
gene id: 290315:CLIM_RS00440
uniprot id: B3EE59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

290315:CLIM RS04330
gene id: 290315:CLIM_RS04330
uniprot id: B3EIB1
names: Similarity
messages: Belongs to the thioredoxin family.

290315:CLIM RS04425
gene id: 290315:CLIM_RS04425
uniprot id: B3EIC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

290315:CLIM RS02155
gene id: 290315:CLIM_RS02155
uniprot id: B3EFY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

290315:CLIM RS00785
gene id: 290315:CLIM_RS00785
uniprot id: B3EEB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

290315:CLIM RS03715
gene id: 290315:CLIM_RS03715
uniprot id: B3EHP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

290315:CLIM RS00030
gene id: 290315:CLIM_RS00030
uniprot id: B3EDN4
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

290315:CLIM RS09160
gene id: 290315:CLIM_RS09160
uniprot id: B3EEZ6
names: Subcellular Location Annotation
messages: Cytoplasm

290315:CLIM RS10050
gene id: 290315:CLIM_RS10050
uniprot id: B3EFR7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

290315:CLIM RS03995
gene id: 290315:CLIM_RS03995
uniprot id: B3EI46
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

290315:CLIM RS05550
gene id: 290315:CLIM_RS05550
uniprot id: B3ECA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

290315:CLIM RS07560
gene id: 290315:CLIM_RS07560
uniprot id: B3EDD6
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

290315:CLIM RS10715
gene id: 290315:CLIM_RS10715
uniprot id: B3EGP3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

290315:CLIM RS06250
gene id: 290315:CLIM_RS06250
uniprot id: B3ECP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

290315:CLIM RS10390
gene id: 290315:CLIM_RS10390
uniprot id: B3EG85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

290315:CLIM RS06835
gene id: 290315:CLIM_RS06835
uniprot id: B3ED05
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

290315:CLIM RS02560
gene id: 290315:CLIM_RS02560
uniprot id: B3EGF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

290315:CLIM RS12340
gene id: 290315:CLIM_RS12340
uniprot id: B3EIG9
names: Similarity
messages: Belongs to the HsdR family.

290315:CLIM RS00475
gene id: 290315:CLIM_RS00475
uniprot id: B3EE66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

290315:CLIM RS08630
gene id: 290315:CLIM_RS08630
uniprot id: B3EEE5
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

290315:CLIM RS00190
gene id: 290315:CLIM_RS00190
uniprot id: B3EDR6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

290315:CLIM RS06170
gene id: 290315:CLIM_RS06170
uniprot id: B3ECM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

290315:CLIM RS02690
gene id: 290315:CLIM_RS02690
uniprot id: B3EGI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

290315:CLIM RS00810
gene id: 290315:CLIM_RS00810
uniprot id: B3EEB9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

290315:CLIM RS01260
gene id: 290315:CLIM_RS01260
uniprot id: B3EEV3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

290315:CLIM RS09990
gene id: 290315:CLIM_RS09990
uniprot id: B3EFQ5
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

290315:CLIM RS11740
gene id: 290315:CLIM_RS11740
uniprot id: B3EHV2
names: Similarity
messages: Belongs to the universal stress protein A family.

290315:CLIM RS02105
gene id: 290315:CLIM_RS02105
uniprot id: B3EFW9
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS02820
gene id: 290315:CLIM_RS02820
uniprot id: B3EGK7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

290315:CLIM RS11115
gene id: 290315:CLIM_RS11115
uniprot id: B3EGX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

290315:CLIM RS02545
gene id: 290315:CLIM_RS02545
uniprot id: B3EGF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

290315:CLIM RS04860
gene id: 290315:CLIM_RS04860
uniprot id: B3EIV2
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

290315:CLIM RS02585
gene id: 290315:CLIM_RS02585
uniprot id: B3EGG2
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS08485
gene id: 290315:CLIM_RS08485
uniprot id: B3EE24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

290315:CLIM RS01560
gene id: 290315:CLIM_RS01560
uniprot id: B3EFB3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

290315:CLIM RS09010
gene id: 290315:CLIM_RS09010
uniprot id: B3EEL7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

290315:CLIM RS02160
gene id: 290315:CLIM_RS02160
uniprot id: B3EFY1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

290315:CLIM RS11200
gene id: 290315:CLIM_RS11200
uniprot id: B3EGZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

290315:CLIM RS12200
gene id: 290315:CLIM_RS12200
uniprot id: B3EIE2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

290315:CLIM RS04515
gene id: 290315:CLIM_RS04515
uniprot id: B3EIN5
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

290315:CLIM RS11245
gene id: 290315:CLIM_RS11245
uniprot id: B3EHA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

290315:CLIM RS01035
gene id: 290315:CLIM_RS01035
uniprot id: B3EEQ8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

290315:CLIM RS11080
gene id: 290315:CLIM_RS11080
uniprot id: B3EGW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

290315:CLIM RS11000
gene id: 290315:CLIM_RS11000
uniprot id: B3EGV0
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

290315:CLIM RS04500
gene id: 290315:CLIM_RS04500
uniprot id: B3EIN2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

290315:CLIM RS01570
gene id: 290315:CLIM_RS01570
uniprot id: B3EFB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

290315:CLIM RS07095
gene id: 290315:CLIM_RS07095
uniprot id: B3ED55
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS09720
gene id: 290315:CLIM_RS09720
uniprot id: B3EFK4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

290315:CLIM RS02195
gene id: 290315:CLIM_RS02195
uniprot id: B3EFY8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

290315:CLIM RS02610
gene id: 290315:CLIM_RS02610
uniprot id: B3EGG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

290315:CLIM RS11255
gene id: 290315:CLIM_RS11255
uniprot id: B3EHA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

290315:CLIM RS10785
gene id: 290315:CLIM_RS10785
uniprot id: B3EGQ8
names: Similarity
messages: Belongs to the arsA ATPase family.

290315:CLIM RS10990
gene id: 290315:CLIM_RS10990
uniprot id: B3EGU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

290315:CLIM RS02860
gene id: 290315:CLIM_RS02860
uniprot id: B3EGL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

290315:CLIM RS10170
gene id: 290315:CLIM_RS10170
uniprot id: B3EG44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

290315:CLIM RS07785
gene id: 290315:CLIM_RS07785
uniprot id: B3EDH8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

290315:CLIM RS04065
gene id: 290315:CLIM_RS04065
uniprot id: B3EI61
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

290315:CLIM RS03400
gene id: 290315:CLIM_RS03400
uniprot id: B3EH78
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

290315:CLIM RS02140
gene id: 290315:CLIM_RS02140
uniprot id: B3EFX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

290315:CLIM RS06300
gene id: 290315:CLIM_RS06300
uniprot id: B3ECQ1
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

290315:CLIM RS12115
gene id: 290315:CLIM_RS12115
uniprot id: B3EI28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

290315:CLIM RS01040
gene id: 290315:CLIM_RS01040
uniprot id: B3EEQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

290315:CLIM RS11040
gene id: 290315:CLIM_RS11040
uniprot id: B3EGV8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

290315:CLIM RS01575
gene id: 290315:CLIM_RS01575
uniprot id: B3EFB6
names: Similarity
messages: Belongs to the YicC/YloC family.

290315:CLIM RS01820
gene id: 290315:CLIM_RS01820
uniprot id: B3EFG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

290315:CLIM RS03970
gene id: 290315:CLIM_RS03970
uniprot id: B3EHU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

290315:CLIM RS08795
gene id: 290315:CLIM_RS08795
uniprot id: B3EEH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

290315:CLIM RS04460
gene id: 290315:CLIM_RS04460
uniprot id: B3EID5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

290315:CLIM RS07630
gene id: 290315:CLIM_RS07630
uniprot id: B3EDE7
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS03170
gene id: 290315:CLIM_RS03170
uniprot id: B3EH30
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

290315:CLIM RS06060
gene id: 290315:CLIM_RS06060
uniprot id: B3ECK5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

290315:CLIM RS02855
gene id: 290315:CLIM_RS02855
uniprot id: B3EGL3
names: Similarity
messages: Belongs to the RecJ family.

290315:CLIM RS00955
gene id: 290315:CLIM_RS00955
uniprot id: B3EEP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS10795
gene id: 290315:CLIM_RS10795
uniprot id: B3EGR0
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS03085
gene id: 290315:CLIM_RS03085
uniprot id: B3EH13
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

290315:CLIM RS06280
gene id: 290315:CLIM_RS06280
uniprot id: B3ECP7
names: Similarity
messages: Belongs to the peptidase S24 family.

290315:CLIM RS07680
gene id: 290315:CLIM_RS07680
uniprot id: B3EDF7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

290315:CLIM RS02595
gene id: 290315:CLIM_RS02595
uniprot id: B3EGG4
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS00155
gene id: 290315:CLIM_RS00155
uniprot id: B3EDQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

290315:CLIM RS10540
gene id: 290315:CLIM_RS10540
uniprot id: B3EGB4
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

290315:CLIM RS06010
gene id: 290315:CLIM_RS06010
uniprot id: B3ECJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

290315:CLIM RS07645
gene id: 290315:CLIM_RS07645
uniprot id: B3EDF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

290315:CLIM RS08960
gene id: 290315:CLIM_RS08960
uniprot id: B3EEK7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

290315:CLIM RS08275
gene id: 290315:CLIM_RS08275
uniprot id: B3EDY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

290315:CLIM RS00355
gene id: 290315:CLIM_RS00355
uniprot id: B3EDU7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

290315:CLIM RS11465
gene id: 290315:CLIM_RS11465
uniprot id: B3EHE4
names: Subcellular Location Annotation
messages: Cytoplasm

290315:CLIM RS09815
gene id: 290315:CLIM_RS09815
uniprot id: B3EFM2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

290315:CLIM RS08995
gene id: 290315:CLIM_RS08995
uniprot id: B3EEL4
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

290315:CLIM RS00385
gene id: 290315:CLIM_RS00385
uniprot id: B3EE49
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

290315:CLIM RS04760
gene id: 290315:CLIM_RS04760
uniprot id: B3EIT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

290315:CLIM RS09870
gene id: 290315:CLIM_RS09870
uniprot id: B3EFN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

290315:CLIM RS11205
gene id: 290315:CLIM_RS11205
uniprot id: B3EH92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

290315:CLIM RS01650
gene id: 290315:CLIM_RS01650
uniprot id: B3EFD1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

290315:CLIM RS09680
gene id: 290315:CLIM_RS09680
uniprot id: B3EFJ7
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

290315:CLIM RS02550
gene id: 290315:CLIM_RS02550
uniprot id: B3EGF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

290315:CLIM RS03155
gene id: 290315:CLIM_RS03155
uniprot id: B3EH27
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

290315:CLIM RS08510
gene id: 290315:CLIM_RS08510
uniprot id: B3EE29
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

290315:CLIM RS03450
gene id: 290315:CLIM_RS03450
uniprot id: B3EH88
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

290315:CLIM RS09040
gene id: 290315:CLIM_RS09040
uniprot id: B3EEM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

290315:CLIM RS11705
gene id: 290315:CLIM_RS11705
uniprot id: B3EHU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

290315:CLIM RS10980
gene id: 290315:CLIM_RS10980
uniprot id: B3EGU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

290315:CLIM RS11420
gene id: 290315:CLIM_RS11420
uniprot id: B3EHD5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

290315:CLIM RS05045
gene id: 290315:CLIM_RS05045
uniprot id: B3EC05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

290315:CLIM RS12425
gene id: 290315:CLIM_RS12425
uniprot id: B3EII6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

290315:CLIM RS08365
gene id: 290315:CLIM_RS08365
uniprot id: B3EE00
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS06980
gene id: 290315:CLIM_RS06980
uniprot id: B3ED32
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

290315:CLIM RS02725
gene id: 290315:CLIM_RS02725
uniprot id: B3EGI8
names: Similarity
messages: Belongs to the MreC family.

290315:CLIM RS12065
gene id: 290315:CLIM_RS12065
uniprot id: B3EI18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

290315:CLIM RS06150
gene id: 290315:CLIM_RS06150
uniprot id: B3ECM1
names: Similarity
messages: Belongs to the glutamate synthase family.

290315:CLIM RS00420
gene id: 290315:CLIM_RS00420
uniprot id: B3EE56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

290315:CLIM RS04765
gene id: 290315:CLIM_RS04765
uniprot id: B3EIT2
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

290315:CLIM RS01205
gene id: 290315:CLIM_RS01205
uniprot id: B3EEU3
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

290315:CLIM RS03210
gene id: 290315:CLIM_RS03210
uniprot id: B3EH38
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

290315:CLIM RS07170
gene id: 290315:CLIM_RS07170
uniprot id: B3ED70
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

290315:CLIM RS01800
gene id: 290315:CLIM_RS01800
uniprot id: B3EFF7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

290315:CLIM RS08970
gene id: 290315:CLIM_RS08970
uniprot id: B3EEK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

290315:CLIM RS12435
gene id: 290315:CLIM_RS12435
uniprot id: B3EII9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

290315:CLIM RS08580
gene id: 290315:CLIM_RS08580
uniprot id: B3EE43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

290315:CLIM RS03120
gene id: 290315:CLIM_RS03120
uniprot id: B3EH20
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

290315:CLIM RS06210
gene id: 290315:CLIM_RS06210
uniprot id: B3ECN3
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS12610
gene id: 290315:CLIM_RS12610
uniprot id: B3EIM1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

290315:CLIM RS01850
gene id: 290315:CLIM_RS01850
uniprot id: B3EFG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

290315:CLIM RS01175
gene id: 290315:CLIM_RS01175
uniprot id: B3EET7
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

290315:CLIM RS05315
gene id: 290315:CLIM_RS05315
uniprot id: B3EC60
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

290315:CLIM RS09830
gene id: 290315:CLIM_RS09830
uniprot id: B3EFM5
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

290315:CLIM RS12120
gene id: 290315:CLIM_RS12120
uniprot id: B3EI29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

290315:CLIM RS11695
gene id: 290315:CLIM_RS11695
uniprot id: B3EHJ0
names: Similarity
messages: Belongs to the CinA family.

290315:CLIM RS10065
gene id: 290315:CLIM_RS10065
uniprot id: B3EFS0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

290315:CLIM RS05295
gene id: 290315:CLIM_RS05295
uniprot id: B3EC56
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS11675
gene id: 290315:CLIM_RS11675
uniprot id: B3EHI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

290315:CLIM RS05945
gene id: 290315:CLIM_RS05945
uniprot id: B3ECI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

290315:CLIM RS11060
gene id: 290315:CLIM_RS11060
uniprot id: B3EGW2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

290315:CLIM RS09090
gene id: 290315:CLIM_RS09090
uniprot id: B3EEN3
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

290315:CLIM RS04960
gene id: 290315:CLIM_RS04960
uniprot id: B3EIX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

290315:CLIM RS06345
gene id: 290315:CLIM_RS06345
uniprot id: B3ECR0
names: Similarity
messages: Belongs to the BMP lipoprotein family.

290315:CLIM RS02850
gene id: 290315:CLIM_RS02850
uniprot id: B3EGL2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

290315:CLIM RS00880
gene id: 290315:CLIM_RS00880
uniprot id: B3EED3
names: Similarity
messages: Belongs to the fabD family.

290315:CLIM RS05970
gene id: 290315:CLIM_RS05970
uniprot id: B3ECI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS00780
gene id: 290315:CLIM_RS00780
uniprot id: B3EEB3
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS12160
gene id: 290315:CLIM_RS12160
uniprot id: B3EI37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

290315:CLIM RS10270
gene id: 290315:CLIM_RS10270
uniprot id: B3EG62
names: Similarity
messages: Belongs to the citrate synthase family.

290315:CLIM RS00340
gene id: 290315:CLIM_RS00340
uniprot id: B3EDU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

290315:CLIM RS11990
gene id: 290315:CLIM_RS11990
uniprot id: B3EI03
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

290315:CLIM RS01545
gene id: 290315:CLIM_RS01545
uniprot id: B3EFB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

290315:CLIM RS10125
gene id: 290315:CLIM_RS10125
uniprot id: B3EFT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

290315:CLIM RS02085
gene id: 290315:CLIM_RS02085
uniprot id: B3EFW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

290315:CLIM RS08110
gene id: 290315:CLIM_RS08110
uniprot id: B3EDV6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

290315:CLIM RS09865
gene id: 290315:CLIM_RS09865
uniprot id: B3EFN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

290315:CLIM RS02180
gene id: 290315:CLIM_RS02180
uniprot id: B3EFY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

290315:CLIM RS08215
gene id: 290315:CLIM_RS08215
uniprot id: B3EDX7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

290315:CLIM RS00775
gene id: 290315:CLIM_RS00775
uniprot id: B3EEB2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

290315:CLIM RS03725
gene id: 290315:CLIM_RS03725
uniprot id: B3EHP3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

290315:CLIM RS04345
gene id: 290315:CLIM_RS04345
uniprot id: B3EIB4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

290315:CLIM RS00530
gene id: 290315:CLIM_RS00530
uniprot id: B3EE77
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

290315:CLIM RS03520
gene id: 290315:CLIM_RS03520
uniprot id: B3EHK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

290315:CLIM RS12615
gene id: 290315:CLIM_RS12615
uniprot id: B3EIM2
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS08185
gene id: 290315:CLIM_RS08185
uniprot id: B3EDX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

290315:CLIM RS04090
gene id: 290315:CLIM_RS04090
uniprot id: B3EI67
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS04805
gene id: 290315:CLIM_RS04805
uniprot id: B3EIU1
names: Similarity
messages: Belongs to the CFA/CMAS family.

290315:CLIM RS04285
gene id: 290315:CLIM_RS04285
uniprot id: B3EIA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

290315:CLIM RS10040
gene id: 290315:CLIM_RS10040
uniprot id: B3EFR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

290315:CLIM RS00805
gene id: 290315:CLIM_RS00805
uniprot id: B3EEB8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

290315:CLIM RS09570
gene id: 290315:CLIM_RS09570
uniprot id: B3EF75
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS11035
gene id: 290315:CLIM_RS11035
uniprot id: B3EGV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

290315:CLIM RS00995
gene id: 290315:CLIM_RS00995
uniprot id: B3EEQ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

290315:CLIM RS12650
gene id: 290315:CLIM_RS12650
uniprot id: B3EIM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

290315:CLIM RS03980
gene id: 290315:CLIM_RS03980
uniprot id: B3EHU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

290315:CLIM RS04845
gene id: 290315:CLIM_RS04845
uniprot id: B3EIU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

290315:CLIM RS00390
gene id: 290315:CLIM_RS00390
uniprot id: B3EE50
names: Similarity
messages: Belongs to the arsA ATPase family.

290315:CLIM RS11075
gene id: 290315:CLIM_RS11075
uniprot id: B3EGW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

290315:CLIM RS01845
gene id: 290315:CLIM_RS01845
uniprot id: B3EFG6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

290315:CLIM RS09880
gene id: 290315:CLIM_RS09880
uniprot id: B3EFN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

290315:CLIM RS09905
gene id: 290315:CLIM_RS09905
uniprot id: B3EFP0
names: Similarity
messages: Belongs to the RuBisCO large chain family.

290315:CLIM RS04490
gene id: 290315:CLIM_RS04490
uniprot id: B3EIE1
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

290315:CLIM RS01805
gene id: 290315:CLIM_RS01805
uniprot id: B3EFF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

290315:CLIM RS02415
gene id: 290315:CLIM_RS02415
uniprot id: B3EG33
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

290315:CLIM RS07010
gene id: 290315:CLIM_RS07010
uniprot id: B3ED38
names: Similarity
messages: Belongs to the peptidase S41A family.

290315:CLIM RS06165
gene id: 290315:CLIM_RS06165
uniprot id: B3ECM4
names: Similarity
messages: In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
messages: In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.

290315:CLIM RS08550
gene id: 290315:CLIM_RS08550
uniprot id: B3EE37
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

290315:CLIM RS08140
gene id: 290315:CLIM_RS08140
uniprot id: B3EDW2
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

290315:CLIM RS04480
gene id: 290315:CLIM_RS04480
uniprot id: B3EID9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

290315:CLIM RS02705
gene id: 290315:CLIM_RS02705
uniprot id: B3EGI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

290315:CLIM RS09130
gene id: 290315:CLIM_RS09130
uniprot id: B3EEZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

290315:CLIM RS10365
gene id: 290315:CLIM_RS10365
uniprot id: B3EG80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS12530
gene id: 290315:CLIM_RS12530
uniprot id: B3EIK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

290315:CLIM RS03080
gene id: 290315:CLIM_RS03080
uniprot id: B3EH12
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

290315:CLIM RS01085
gene id: 290315:CLIM_RS01085
uniprot id: B3EER8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

290315:CLIM RS11755
gene id: 290315:CLIM_RS11755
uniprot id: B3EHV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

290315:CLIM RS11700
gene id: 290315:CLIM_RS11700
uniprot id: B3EHJ1
names: Similarity
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

290315:CLIM RS09735
gene id: 290315:CLIM_RS09735
uniprot id: B3EFK7
names: Similarity
messages: Belongs to the glutamate synthase family.

290315:CLIM RS08385
gene id: 290315:CLIM_RS08385
uniprot id: B3EE03
names: Subcellular Location Annotation
messages: Secreted

290315:CLIM RS12520
gene id: 290315:CLIM_RS12520
uniprot id: B3EIK3
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

290315:CLIM RS01050
gene id: 290315:CLIM_RS01050
uniprot id: B3EER1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

290315:CLIM RS09765
gene id: 290315:CLIM_RS09765
uniprot id: B3EFL3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

290315:CLIM RS12030
gene id: 290315:CLIM_RS12030
uniprot id: B3EI10
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

290315:CLIM RS08565
gene id: 290315:CLIM_RS08565
uniprot id: B3EE40
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

290315:CLIM RS09855
gene id: 290315:CLIM_RS09855
uniprot id: B3EFN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

290315:CLIM RS01045
gene id: 290315:CLIM_RS01045
uniprot id: B3EER0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

290315:CLIM RS12480
gene id: 290315:CLIM_RS12480
uniprot id: B3EIJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has four main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains (By similarity).

290315:CLIM RS02075
gene id: 290315:CLIM_RS02075
uniprot id: B3EFW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

290315:CLIM RS03130
gene id: 290315:CLIM_RS03130
uniprot id: B3EH22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

290315:CLIM RS03135
gene id: 290315:CLIM_RS03135
uniprot id: B3EH23
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

290315:CLIM RS07715
gene id: 290315:CLIM_RS07715
uniprot id: B3EDG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

290315:CLIM RS11045
gene id: 290315:CLIM_RS11045
uniprot id: B3EGV9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

290315:CLIM RS05375
gene id: 290315:CLIM_RS05375
uniprot id: B3EC72
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

290315:CLIM RS03440
gene id: 290315:CLIM_RS03440
uniprot id: B3EH86
names: Similarity
messages: Belongs to the P(II) protein family.

290315:CLIM RS08990
gene id: 290315:CLIM_RS08990
uniprot id: B3EEL3
names: Similarity
messages: Belongs to the HupF/HypC family.

290315:CLIM RS13135
gene id: 290315:CLIM_RS13135
uniprot id: B3EGW7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

290315:CLIM RS11190
gene id: 290315:CLIM_RS11190
uniprot id: B3EGY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

290315:CLIM RS02055
gene id: 290315:CLIM_RS02055
uniprot id: B3EFV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

290315:CLIM RS09360
gene id: 290315:CLIM_RS09360
uniprot id: B3EF37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

290315:CLIM RS11545
gene id: 290315:CLIM_RS11545
uniprot id: B3EHG0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

290315:CLIM RS02270
gene id: 290315:CLIM_RS02270
uniprot id: B3EG02
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

290315:CLIM RS05615
gene id: 290315:CLIM_RS05615
uniprot id: B3ECB9
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

290315:CLIM RS01985
gene id: 290315:CLIM_RS01985
uniprot id: B3EFU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

290315:CLIM RS12050
gene id: 290315:CLIM_RS12050
uniprot id: B3EI14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

290315:CLIM RS11120
gene id: 290315:CLIM_RS11120
uniprot id: B3EGX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

290315:CLIM RS13170
gene id: 290315:CLIM_RS13170
uniprot id: B3EIN0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

290315:CLIM RS08320
gene id: 290315:CLIM_RS08320
uniprot id: B3EDZ1
names: Similarity
messages: Belongs to the ArsC family.

290315:CLIM RS10815
gene id: 290315:CLIM_RS10815
uniprot id: B3EGR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

290315:CLIM RS06175
gene id: 290315:CLIM_RS06175
uniprot id: B3ECM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

290315:CLIM RS03760
gene id: 290315:CLIM_RS03760
uniprot id: B3EHP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

290315:CLIM RS08745
gene id: 290315:CLIM_RS08745
uniprot id: B3EEG6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

290315:CLIM RS10120
gene id: 290315:CLIM_RS10120
uniprot id: B3EFT1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

290315:CLIM RS10445
gene id: 290315:CLIM_RS10445
uniprot id: B3EG95
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

290315:CLIM RS12525
gene id: 290315:CLIM_RS12525
uniprot id: B3EIK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS03720
gene id: 290315:CLIM_RS03720
uniprot id: B3EHP2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

290315:CLIM RS09985
gene id: 290315:CLIM_RS09985
uniprot id: B3EFQ4
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS11025
gene id: 290315:CLIM_RS11025
uniprot id: B3EGV5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BchN/ChlN family.
messages: Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
messages: Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits.

290315:CLIM RS06600
gene id: 290315:CLIM_RS06600
uniprot id: B3ECW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

290315:CLIM RS12270
gene id: 290315:CLIM_RS12270
uniprot id: B3EIF6
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

290315:CLIM RS00815
gene id: 290315:CLIM_RS00815
uniprot id: B3EEC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

290315:CLIM RS04630
gene id: 290315:CLIM_RS04630
uniprot id: B3EIQ8
names: Similarity
messages: Belongs to the UPF0047 family.

290315:CLIM RS04945
gene id: 290315:CLIM_RS04945
uniprot id: B3EIW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

290315:CLIM RS01070
gene id: 290315:CLIM_RS01070
uniprot id: B3EER5
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

290315:CLIM RS08520
gene id: 290315:CLIM_RS08520
uniprot id: B3EE31
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

290315:CLIM RS08820
gene id: 290315:CLIM_RS08820
uniprot id: B3EEI1
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

290315:CLIM RS11015
gene id: 290315:CLIM_RS11015
uniprot id: B3EGV3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
messages: Homodimer. Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB.

290315:CLIM RS00025
gene id: 290315:CLIM_RS00025
uniprot id: B3EDN3
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

290315:CLIM RS11020
gene id: 290315:CLIM_RS11020
uniprot id: B3EGV4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ChlB/BchB/BchZ family.
messages: Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
messages: Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits.

290315:CLIM RS04150
gene id: 290315:CLIM_RS04150
uniprot id: B3EI78
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

290315:CLIM RS05080
gene id: 290315:CLIM_RS05080
uniprot id: B3EC12
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

290315:CLIM RS04885
gene id: 290315:CLIM_RS04885
uniprot id: B3EIV7
names: Similarity
messages: Belongs to the P(II) protein family.

290315:CLIM RS02090
gene id: 290315:CLIM_RS02090
uniprot id: B3EFW6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

290315:CLIM RS00060
gene id: 290315:CLIM_RS00060
uniprot id: B3EDP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

290315:CLIM RS06230
gene id: 290315:CLIM_RS06230
uniprot id: B3ECN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

290315:CLIM RS03990
gene id: 290315:CLIM_RS03990
uniprot id: B3EI45
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

290315:CLIM RS09175
gene id: 290315:CLIM_RS09175
uniprot id: B3EF00
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

290315:CLIM RS08340
gene id: 290315:CLIM_RS08340
uniprot id: B3EDZ5
names: Similarity
messages: Belongs to the AlaDH/PNT family.

290315:CLIM RS09060
gene id: 290315:CLIM_RS09060
uniprot id: B3EEM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

290315:CLIM RS09270
gene id: 290315:CLIM_RS09270
uniprot id: B3EF18
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

290315:CLIM RS04980
gene id: 290315:CLIM_RS04980
uniprot id: B3EIX6
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

290315:CLIM RS08130
gene id: 290315:CLIM_RS08130
uniprot id: B3EDW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

290315:CLIM RS03540
gene id: 290315:CLIM_RS03540
uniprot id: B3EHK6
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS01920
gene id: 290315:CLIM_RS01920
uniprot id: B3EFI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

290315:CLIM RS06880
gene id: 290315:CLIM_RS06880
uniprot id: B3ED13
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

290315:CLIM RS08050
gene id: 290315:CLIM_RS08050
uniprot id: B3EDM2
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS10080
gene id: 290315:CLIM_RS10080
uniprot id: B3EFS3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

290315:CLIM RS05025
gene id: 290315:CLIM_RS05025
uniprot id: B3EC01
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

290315:CLIM RS04295
gene id: 290315:CLIM_RS04295
uniprot id: B3EIA4
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

290315:CLIM RS08655
gene id: 290315:CLIM_RS08655
uniprot id: B3EEE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

290315:CLIM RS08270
gene id: 290315:CLIM_RS08270
uniprot id: B3EDY2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

290315:CLIM RS11055
gene id: 290315:CLIM_RS11055
uniprot id: B3EGW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

290315:CLIM RS03185
gene id: 290315:CLIM_RS03185
uniprot id: B3EH33
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

290315:CLIM RS05130
gene id: 290315:CLIM_RS05130
uniprot id: B3EC20
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

290315:CLIM RS05485
gene id: 290315:CLIM_RS05485
uniprot id: B3EC94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

290315:CLIM RS01000
gene id: 290315:CLIM_RS01000
uniprot id: B3EEQ5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

290315:CLIM RS11845
gene id: 290315:CLIM_RS11845
uniprot id: B3EHX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BChl C/E-binding protein family.
messages: Component of the photosynthetic apparatus.
messages: chlorosome envelope

290315:CLIM RS12475
gene id: 290315:CLIM_RS12475
uniprot id: B3EIJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

290315:CLIM RS03145
gene id: 290315:CLIM_RS03145
uniprot id: B3EH25
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

290315:CLIM RS02425
gene id: 290315:CLIM_RS02425
uniprot id: B3EG35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

290315:CLIM RS04055
gene id: 290315:CLIM_RS04055
uniprot id: B3EI59
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

290315:CLIM RS06595
gene id: 290315:CLIM_RS06595
uniprot id: B3ECV9
names: Similarity
messages: Belongs to the peptidase S1 family.

290315:CLIM RS08430
gene id: 290315:CLIM_RS08430
uniprot id: B3EE12
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

290315:CLIM RS12545
gene id: 290315:CLIM_RS12545
uniprot id: B3EIK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

290315:CLIM RS03370
gene id: 290315:CLIM_RS03370
uniprot id: B3EH71
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

290315:CLIM RS09180
gene id: 290315:CLIM_RS09180
uniprot id: B3EF01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

290315:CLIM RS06020
gene id: 290315:CLIM_RS06020
uniprot id: B3ECJ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS03665
gene id: 290315:CLIM_RS03665
uniprot id: B3EHN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

290315:CLIM RS07570
gene id: 290315:CLIM_RS07570
uniprot id: B3EDD8
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

290315:CLIM RS08950
gene id: 290315:CLIM_RS08950
uniprot id: B3EEK5
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

290315:CLIM RS08195
gene id: 290315:CLIM_RS08195
uniprot id: B3EDX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

290315:CLIM RS03855
gene id: 290315:CLIM_RS03855
uniprot id: B3EHR7
names: Similarity
messages: Belongs to the AlaDH/PNT family.

290315:CLIM RS00515
gene id: 290315:CLIM_RS00515
uniprot id: B3EE74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

290315:CLIM RS05115
gene id: 290315:CLIM_RS05115
uniprot id: B3EC17
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

290315:CLIM RS01790
gene id: 290315:CLIM_RS01790
uniprot id: B3EFF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

290315:CLIM RS05560
gene id: 290315:CLIM_RS05560
uniprot id: B3ECA8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS08675
gene id: 290315:CLIM_RS08675
uniprot id: B3EEF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

290315:CLIM RS12605
gene id: 290315:CLIM_RS12605
uniprot id: B3EIM0
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

290315:CLIM RS02665
gene id: 290315:CLIM_RS02665
uniprot id: B3EGH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

290315:CLIM RS05925
gene id: 290315:CLIM_RS05925
uniprot id: B3ECH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

290315:CLIM RS01635
gene id: 290315:CLIM_RS01635
uniprot id: B3EFC8
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS09005
gene id: 290315:CLIM_RS09005
uniprot id: B3EEL6
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

290315:CLIM RS09405
gene id: 290315:CLIM_RS09405
uniprot id: B3EF43
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

290315:CLIM RS03215
gene id: 290315:CLIM_RS03215
uniprot id: B3EH39
names: Similarity
messages: Belongs to the peptidase M24B family.

290315:CLIM RS09045
gene id: 290315:CLIM_RS09045
uniprot id: B3EEM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

290315:CLIM RS04545
gene id: 290315:CLIM_RS04545
uniprot id: B3EIP1
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

290315:CLIM RS04750
gene id: 290315:CLIM_RS04750
uniprot id: B3EIS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

290315:CLIM RS11940
gene id: 290315:CLIM_RS11940
uniprot id: B3EHZ2
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

290315:CLIM RS05570
gene id: 290315:CLIM_RS05570
uniprot id: B3ECB0
names: Similarity
messages: Belongs to the sigma-54 factor family.

290315:CLIM RS10145
gene id: 290315:CLIM_RS10145
uniprot id: B3EFT6
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

290315:CLIM RS10965
gene id: 290315:CLIM_RS10965
uniprot id: B3EGU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

290315:CLIM RS10730
gene id: 290315:CLIM_RS10730
uniprot id: B3EGP7
names: Similarity
messages: Belongs to the peptidase M16 family.

290315:CLIM RS07690
gene id: 290315:CLIM_RS07690
uniprot id: B3EDF9
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS12720
gene id: 290315:CLIM_RS12720
uniprot id: B3ECQ2
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

290315:CLIM RS01700
gene id: 290315:CLIM_RS01700
uniprot id: B3EFD7
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

290315:CLIM RS00770
gene id: 290315:CLIM_RS00770
uniprot id: B3EEB1
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

290315:CLIM RS04985
gene id: 290315:CLIM_RS04985
uniprot id: B3EIX7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

290315:CLIM RS03250
gene id: 290315:CLIM_RS03250
uniprot id: B3EH46
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

290315:CLIM RS01620
gene id: 290315:CLIM_RS01620
uniprot id: B3EFC5
names: Similarity
messages: Belongs to the DprA/Smf family.

290315:CLIM RS08715
gene id: 290315:CLIM_RS08715
uniprot id: B3EEG0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

290315:CLIM RS07550
gene id: 290315:CLIM_RS07550
uniprot id: B3EDD4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

290315:CLIM RS01025
gene id: 290315:CLIM_RS01025
uniprot id: B3EEQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

290315:CLIM RS10955
gene id: 290315:CLIM_RS10955
uniprot id: B3EGU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

290315:CLIM RS03355
gene id: 290315:CLIM_RS03355
uniprot id: B3EH68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

290315:CLIM RS10450
gene id: 290315:CLIM_RS10450
uniprot id: B3EG96
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS04965
gene id: 290315:CLIM_RS04965
uniprot id: B3EIX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

290315:CLIM RS06095
gene id: 290315:CLIM_RS06095
uniprot id: B3ECL0
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS02615
gene id: 290315:CLIM_RS02615
uniprot id: B3EGG8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

290315:CLIM RS02395
gene id: 290315:CLIM_RS02395
uniprot id: B3EG29
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS03650
gene id: 290315:CLIM_RS03650
uniprot id: B3EHM8
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

290315:CLIM RS01630
gene id: 290315:CLIM_RS01630
uniprot id: B3EFC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).

290315:CLIM RS11225
gene id: 290315:CLIM_RS11225
uniprot id: B3EH96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

290315:CLIM RS08170
gene id: 290315:CLIM_RS08170
uniprot id: B3EDW8
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS06920
gene id: 290315:CLIM_RS06920
uniprot id: B3ED20
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

290315:CLIM RS00010
gene id: 290315:CLIM_RS00010
uniprot id: B3EDN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

290315:CLIM RS06785
gene id: 290315:CLIM_RS06785
uniprot id: B3ECZ5
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

290315:CLIM RS02390
gene id: 290315:CLIM_RS02390
uniprot id: B3EG28
names: Similarity
messages: Belongs to the TrpC family.

290315:CLIM RS05905
gene id: 290315:CLIM_RS05905
uniprot id: B3ECH5
names: Similarity
messages: Belongs to the SAICAR synthetase family.

290315:CLIM RS06375
gene id: 290315:CLIM_RS06375
uniprot id: B3ECR6
names: Similarity
messages: Belongs to the peptidase C40 family.

290315:CLIM RS08730
gene id: 290315:CLIM_RS08730
uniprot id: B3EEG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

290315:CLIM RS05580
gene id: 290315:CLIM_RS05580
uniprot id: B3ECB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

290315:CLIM RS00080
gene id: 290315:CLIM_RS00080
uniprot id: B3EDP4
names: Similarity
messages: Belongs to the UPF0102 family.

290315:CLIM RS06780
gene id: 290315:CLIM_RS06780
uniprot id: B3ECZ4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

290315:CLIM RS12560
gene id: 290315:CLIM_RS12560
uniprot id: B3EIL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

290315:CLIM RS03645
gene id: 290315:CLIM_RS03645
uniprot id: B3EHM7
names: Similarity
messages: Belongs to the YoeB family.

290315:CLIM RS12240
gene id: 290315:CLIM_RS12240
uniprot id: B3EIF0
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

290315:CLIM RS03965
gene id: 290315:CLIM_RS03965
uniprot id: B3EHU0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

290315:CLIM RS01515
gene id: 290315:CLIM_RS01515
uniprot id: B3EFA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

290315:CLIM RS08420
gene id: 290315:CLIM_RS08420
uniprot id: B3EE10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

290315:CLIM RS11580
gene id: 290315:CLIM_RS11580
uniprot id: B3EHG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

290315:CLIM RS08610
gene id: 290315:CLIM_RS08610
uniprot id: B3EEE1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

290315:CLIM RS09775
gene id: 290315:CLIM_RS09775
uniprot id: B3EFL4
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS09020
gene id: 290315:CLIM_RS09020
uniprot id: B3EEL9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

290315:CLIM RS11065
gene id: 290315:CLIM_RS11065
uniprot id: B3EGW3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

290315:CLIM RS01385
gene id: 290315:CLIM_RS01385
uniprot id: B3EEX6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

290315:CLIM RS10930
gene id: 290315:CLIM_RS10930
uniprot id: B3EGT6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

290315:CLIM RS04075
gene id: 290315:CLIM_RS04075
uniprot id: B3EI63
names: Similarity
messages: Belongs to the thioredoxin family.

290315:CLIM RS12025
gene id: 290315:CLIM_RS12025
uniprot id: B3EI09
names: Similarity
messages: Belongs to the UPF0166 family.

290315:CLIM RS06985
gene id: 290315:CLIM_RS06985
uniprot id: B3ED33
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

290315:CLIM RS08815
gene id: 290315:CLIM_RS08815
uniprot id: B3EEI0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

290315:CLIM RS02290
gene id: 290315:CLIM_RS02290
uniprot id: B3EG06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

290315:CLIM RS02685
gene id: 290315:CLIM_RS02685
uniprot id: B3EGI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

290315:CLIM RS00800
gene id: 290315:CLIM_RS00800
uniprot id: B3EEB7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

290315:CLIM RS08980
gene id: 290315:CLIM_RS08980
uniprot id: B3EEL1
names: Similarity
messages: Belongs to the HypE family.

290315:CLIM RS06270
gene id: 290315:CLIM_RS06270
uniprot id: B3ECP5
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

290315:CLIM RS00110
gene id: 290315:CLIM_RS00110
uniprot id: B3EDQ0
names: Similarity
messages: Belongs to the geranylgeranyl reductase family. ChlP subfamily.

290315:CLIM RS02740
gene id: 290315:CLIM_RS02740
uniprot id: B3EGJ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

290315:CLIM RS09860
gene id: 290315:CLIM_RS09860
uniprot id: B3EFN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

290315:CLIM RS00115
gene id: 290315:CLIM_RS00115
uniprot id: B3EDQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

290315:CLIM RS11535
gene id: 290315:CLIM_RS11535
uniprot id: B3EHF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

290315:CLIM RS06960
gene id: 290315:CLIM_RS06960
uniprot id: B3ED28
names: Similarity
messages: Belongs to the Nth/MutY family.

290315:CLIM RS08175
gene id: 290315:CLIM_RS08175
uniprot id: B3EDW9
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS05500
gene id: 290315:CLIM_RS05500
uniprot id: B3EC97
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

290315:CLIM RS11770
gene id: 290315:CLIM_RS11770
uniprot id: B3EHV8
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

290315:CLIM RS07025
gene id: 290315:CLIM_RS07025
uniprot id: B3ED41
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

290315:CLIM RS00435
gene id: 290315:CLIM_RS00435
uniprot id: B3EE58
names: Similarity
messages: Belongs to the acylphosphatase family.

290315:CLIM RS03825
gene id: 290315:CLIM_RS03825
uniprot id: B3EHR1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

290315:CLIM RS12170
gene id: 290315:CLIM_RS12170
uniprot id: B3EI39
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

290315:CLIM RS00450
gene id: 290315:CLIM_RS00450
uniprot id: B3EE61
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

290315:CLIM RS03435
gene id: 290315:CLIM_RS03435
uniprot id: B3EH85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

290315:CLIM RS02790
gene id: 290315:CLIM_RS02790
uniprot id: B3EGK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

290315:CLIM RS08460
gene id: 290315:CLIM_RS08460
uniprot id: B3EE18
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

290315:CLIM RS07995
gene id: 290315:CLIM_RS07995
uniprot id: B3EDL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

290315:CLIM RS03570
gene id: 290315:CLIM_RS03570
uniprot id: B3EHL2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

290315:CLIM RS02870
gene id: 290315:CLIM_RS02870
uniprot id: B3EGL6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

290315:CLIM RS03740
gene id: 290315:CLIM_RS03740
uniprot id: B3EHP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

290315:CLIM RS07575
gene id: 290315:CLIM_RS07575
uniprot id: B3EDD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

290315:CLIM RS04935
gene id: 290315:CLIM_RS04935
uniprot id: B3EIW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

290315:CLIM RS11720
gene id: 290315:CLIM_RS11720
uniprot id: B3EHU8
names: Similarity
messages: Belongs to the threonine synthase family.

290315:CLIM RS01730
gene id: 290315:CLIM_RS01730
uniprot id: B3EFE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

290315:CLIM RS03490
gene id: 290315:CLIM_RS03490
uniprot id: B3EHJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

290315:CLIM RS03905
gene id: 290315:CLIM_RS03905
uniprot id: B3EHS7
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

290315:CLIM RS04080
gene id: 290315:CLIM_RS04080
uniprot id: B3EI64
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

290315:CLIM RS02185
gene id: 290315:CLIM_RS02185
uniprot id: B3EFY6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS05335
gene id: 290315:CLIM_RS05335
uniprot id: B3EC64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

290315:CLIM RS02825
gene id: 290315:CLIM_RS02825
uniprot id: B3EGK8
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

290315:CLIM RS07335
gene id: 290315:CLIM_RS07335
uniprot id: B3EDA1
names: Similarity
messages: Belongs to the HepT RNase toxin family.

290315:CLIM RS02430
gene id: 290315:CLIM_RS02430
uniprot id: B3EG36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

290315:CLIM RS04435
gene id: 290315:CLIM_RS04435
uniprot id: B3EID0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

290315:CLIM RS05545
gene id: 290315:CLIM_RS05545
uniprot id: B3ECA5
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

290315:CLIM RS02540
gene id: 290315:CLIM_RS02540
uniprot id: B3EGF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

290315:CLIM RS07775
gene id: 290315:CLIM_RS07775
uniprot id: B3EDH6
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

290315:CLIM RS00180
gene id: 290315:CLIM_RS00180
uniprot id: B3EDR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

290315:CLIM RS04020
gene id: 290315:CLIM_RS04020
uniprot id: B3EI51
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS11475
gene id: 290315:CLIM_RS11475
uniprot id: B3EHE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

290315:CLIM RS07965
gene id: 290315:CLIM_RS07965
uniprot id: B3EDK6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

290315:CLIM RS03425
gene id: 290315:CLIM_RS03425
uniprot id: B3EH83
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

290315:CLIM RS08400
gene id: 290315:CLIM_RS08400
uniprot id: B3EE06
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

290315:CLIM RS11885
gene id: 290315:CLIM_RS11885
uniprot id: B3EHY1
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

290315:CLIM RS05240
gene id: 290315:CLIM_RS05240
uniprot id: B3EC46
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

290315:CLIM RS09290
gene id: 290315:CLIM_RS09290
uniprot id: B3EF22
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

290315:CLIM RS05180
gene id: 290315:CLIM_RS05180
uniprot id: B3EC29
names: Similarity
messages: Belongs to the heat shock protein 70 family.

290315:CLIM RS03165
gene id: 290315:CLIM_RS03165
uniprot id: B3EH29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

290315:CLIM RS07090
gene id: 290315:CLIM_RS07090
uniprot id: B3ED54
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

290315:CLIM RS05320
gene id: 290315:CLIM_RS05320
uniprot id: B3EC61
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

290315:CLIM RS07470
gene id: 290315:CLIM_RS07470
uniprot id: B3EDC1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

290315:CLIM RS07460
gene id: 290315:CLIM_RS07460
uniprot id: B3EDB9
names: Function
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.
messages: Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.

290315:CLIM RS00820
gene id: 290315:CLIM_RS00820
uniprot id: B3EEC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

290315:CLIM RS11710
gene id: 290315:CLIM_RS11710
uniprot id: B3EHU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a, b, b' and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

290315:CLIM RS01725
gene id: 290315:CLIM_RS01725
uniprot id: B3EFE2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

290315:CLIM RS04665
gene id: 290315:CLIM_RS04665
uniprot id: B3EIR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

290315:CLIM RS03395
gene id: 290315:CLIM_RS03395
uniprot id: B3EH77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

290315:CLIM RS10710
gene id: 290315:CLIM_RS10710
uniprot id: B3EGP2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS06630
gene id: 290315:CLIM_RS06630
uniprot id: B3ECW5
names: Similarity
messages: Belongs to the XFP family.

290315:CLIM RS03830
gene id: 290315:CLIM_RS03830
uniprot id: B3EHR2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

290315:CLIM RS07465
gene id: 290315:CLIM_RS07465
uniprot id: B3EDC0
names: Function
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.
messages: Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.

290315:CLIM RS04195
gene id: 290315:CLIM_RS04195
uniprot id: B3EI86
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

290315:CLIM RS03710
gene id: 290315:CLIM_RS03710
uniprot id: B3EHP0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

290315:CLIM RS01625
gene id: 290315:CLIM_RS01625
uniprot id: B3EFC6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

290315:CLIM RS03225
gene id: 290315:CLIM_RS03225
uniprot id: B3EH41
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS05890
gene id: 290315:CLIM_RS05890
uniprot id: B3ECH2
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS06295
gene id: 290315:CLIM_RS06295
uniprot id: B3ECQ0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

290315:CLIM RS03180
gene id: 290315:CLIM_RS03180
uniprot id: B3EH32
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

290315:CLIM RS03755
gene id: 290315:CLIM_RS03755
uniprot id: B3EHP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TolB family.
messages: Periplasm

290315:CLIM RS08545
gene id: 290315:CLIM_RS08545
uniprot id: B3EE36
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

290315:CLIM RS08000
gene id: 290315:CLIM_RS08000
uniprot id: B3EDL3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

290315:CLIM RS07050
gene id: 290315:CLIM_RS07050
uniprot id: B3ED46
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

290315:CLIM RS00825
gene id: 290315:CLIM_RS00825
uniprot id: B3EEC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ChlB/BchB/BchZ family.
messages: Chlorophyllide reductase is composed of three subunits; BchX, BchY and BchZ. Forms a heterodimer of one BchY and one BchZ subunit.
messages: Converts chlorophylls (Chl) into bacteriochlorophylls (BChl) by reducing ring B of the tetrapyrrole.

290315:CLIM RS01765
gene id: 290315:CLIM_RS01765
uniprot id: B3EFF0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

290315:CLIM RS05585
gene id: 290315:CLIM_RS05585
uniprot id: B3ECB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

290315:CLIM RS11095
gene id: 290315:CLIM_RS11095
uniprot id: B3EGX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

290315:CLIM RS11590
gene id: 290315:CLIM_RS11590
uniprot id: B3EHG9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

290315:CLIM RS06190
gene id: 290315:CLIM_RS06190
uniprot id: B3ECM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

290315:CLIM RS11220
gene id: 290315:CLIM_RS11220
uniprot id: B3EH95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

290315:CLIM RS05840
gene id: 290315:CLIM_RS05840
uniprot id: B3ECG2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

290315:CLIM RS00350
gene id: 290315:CLIM_RS00350
uniprot id: B3EDU6
names: Similarity
messages: Belongs to the universal stress protein A family.

290315:CLIM RS10830
gene id: 290315:CLIM_RS10830
uniprot id: B3EGR7
names: Similarity
messages: Belongs to the Mg-chelatase subunit H family.

290315:CLIM RS09740
gene id: 290315:CLIM_RS09740
uniprot id: B3EFK8
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

290315:CLIM RS05725
gene id: 290315:CLIM_RS05725
uniprot id: B3ECE0
names: Similarity
messages: Belongs to the UPF0251 family.

290315:CLIM RS10625
gene id: 290315:CLIM_RS10625
uniprot id: B3EGC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

290315:CLIM RS00275
gene id: 290315:CLIM_RS00275
uniprot id: B3EDT1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

290315:CLIM RS09805
gene id: 290315:CLIM_RS09805
uniprot id: B3EFM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

290315:CLIM RS10490
gene id: 290315:CLIM_RS10490
uniprot id: B3EGA4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS00950
gene id: 290315:CLIM_RS00950
uniprot id: B3EEP6
names: Similarity
messages: Belongs to the MEMO1 family.

290315:CLIM RS01945
gene id: 290315:CLIM_RS01945
uniprot id: B3EFI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

290315:CLIM RS00075
gene id: 290315:CLIM_RS00075
uniprot id: B3EDP3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

290315:CLIM RS03245
gene id: 290315:CLIM_RS03245
uniprot id: B3EH45
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

290315:CLIM RS08785
gene id: 290315:CLIM_RS08785
uniprot id: B3EEH4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

290315:CLIM RS11595
gene id: 290315:CLIM_RS11595
uniprot id: B3EHH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

290315:CLIM RS07730
gene id: 290315:CLIM_RS07730
uniprot id: B3EDG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

290315:CLIM RS02600
gene id: 290315:CLIM_RS02600
uniprot id: B3EGG5
names: Similarity
messages: Belongs to the AdoMet synthetase 2 family.

290315:CLIM RS03430
gene id: 290315:CLIM_RS03430
uniprot id: B3EH84
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

290315:CLIM RS02810
gene id: 290315:CLIM_RS02810
uniprot id: B3EGK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

290315:CLIM RS06205
gene id: 290315:CLIM_RS06205
uniprot id: B3ECN2
names: Similarity
messages: Belongs to the rubredoxin family.

290315:CLIM RS11640
gene id: 290315:CLIM_RS11640
uniprot id: B3EHI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

290315:CLIM RS09620
gene id: 290315:CLIM_RS09620
uniprot id: B3EF85
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS00375
gene id: 290315:CLIM_RS00375
uniprot id: B3EDV1
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

290315:CLIM RS10225
gene id: 290315:CLIM_RS10225
uniprot id: B3EG53
names: Similarity
messages: Belongs to the RelE toxin family.

290315:CLIM RS03160
gene id: 290315:CLIM_RS03160
uniprot id: B3EH28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

290315:CLIM RS10750
gene id: 290315:CLIM_RS10750
uniprot id: B3EGQ1
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

290315:CLIM RS00140
gene id: 290315:CLIM_RS00140
uniprot id: B3EDQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

290315:CLIM RS00135
gene id: 290315:CLIM_RS00135
uniprot id: B3EDQ6
names: Similarity
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

290315:CLIM RS10515
gene id: 290315:CLIM_RS10515
uniprot id: B3EGA9
names: Similarity
messages: Belongs to the universal stress protein A family.

290315:CLIM RS01105
gene id: 290315:CLIM_RS01105
uniprot id: B3EES2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

290315:CLIM RS07225
gene id: 290315:CLIM_RS07225
uniprot id: B3ED81
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane

290315:CLIM RS01340
gene id: 290315:CLIM_RS01340
uniprot id: B3EEW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

290315:CLIM RS10375
gene id: 290315:CLIM_RS10375
uniprot id: B3EG82
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

290315:CLIM RS03865
gene id: 290315:CLIM_RS03865
uniprot id: B3EHR9
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

290315:CLIM RS00685
gene id: 290315:CLIM_RS00685
uniprot id: B3EEA0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

290315:CLIM RS04250
gene id: 290315:CLIM_RS04250
uniprot id: B3EI95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

290315:CLIM RS07695
gene id: 290315:CLIM_RS07695
uniprot id: B3EDG0
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS02000
gene id: 290315:CLIM_RS02000
uniprot id: B3EFU8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

290315:CLIM RS12095
gene id: 290315:CLIM_RS12095
uniprot id: B3EI24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

290315:CLIM RS07315
gene id: 290315:CLIM_RS07315
uniprot id: B3ED98
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

290315:CLIM RS09885
gene id: 290315:CLIM_RS09885
uniprot id: B3EFN6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

290315:CLIM RS05865
gene id: 290315:CLIM_RS05865
uniprot id: B3ECG7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

290315:CLIM RS12620
gene id: 290315:CLIM_RS12620
uniprot id: B3EIM3
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS09075
gene id: 290315:CLIM_RS09075
uniprot id: B3EEN0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

290315:CLIM RS01995
gene id: 290315:CLIM_RS01995
uniprot id: B3EFU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

290315:CLIM RS08465
gene id: 290315:CLIM_RS08465
uniprot id: B3EE19
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

290315:CLIM RS01860
gene id: 290315:CLIM_RS01860
uniprot id: B3EFG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

290315:CLIM RS04970
gene id: 290315:CLIM_RS04970
uniprot id: B3EIX4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

290315:CLIM RS01420
gene id: 290315:CLIM_RS01420
uniprot id: B3EEY4
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS10995
gene id: 290315:CLIM_RS10995
uniprot id: B3EGU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

290315:CLIM RS06080
gene id: 290315:CLIM_RS06080
uniprot id: B3ECK8
names: Similarity
messages: Belongs to the arsA ATPase family.

290315:CLIM RS04855
gene id: 290315:CLIM_RS04855
uniprot id: B3EIV1
names: Similarity
messages: Belongs to the arsA ATPase family.

290315:CLIM RS06910
gene id: 290315:CLIM_RS06910
uniprot id: B3ED19
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

290315:CLIM RS08470
gene id: 290315:CLIM_RS08470
uniprot id: B3EE20
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

290315:CLIM RS10110
gene id: 290315:CLIM_RS10110
uniprot id: B3EFS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

290315:CLIM RS10740
gene id: 290315:CLIM_RS10740
uniprot id: B3EGP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

290315:CLIM RS07780
gene id: 290315:CLIM_RS07780
uniprot id: B3EDH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

290315:CLIM RS08935
gene id: 290315:CLIM_RS08935
uniprot id: B3EEK2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

290315:CLIM RS04290
gene id: 290315:CLIM_RS04290
uniprot id: B3EIA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

290315:CLIM RS09155
gene id: 290315:CLIM_RS09155
uniprot id: B3EEZ5
names: Similarity
messages: Belongs to the UPF0758 family.

290315:CLIM RS11485
gene id: 290315:CLIM_RS11485
uniprot id: B3EHE8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

290315:CLIM RS08555
gene id: 290315:CLIM_RS08555
uniprot id: B3EE38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

290315:CLIM RS02205
gene id: 290315:CLIM_RS02205
uniprot id: B3EFZ0
names: Similarity
messages: Belongs to the alkaline phosphatase family.

290315:CLIM RS03815
gene id: 290315:CLIM_RS03815
uniprot id: B3EHR0
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

290315:CLIM RS10130
gene id: 290315:CLIM_RS10130
uniprot id: B3EFT3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

290315:CLIM RS03275
gene id: 290315:CLIM_RS03275
uniprot id: B3EH53
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

290315:CLIM RS11915
gene id: 290315:CLIM_RS11915
uniprot id: B3EHY7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS02335
gene id: 290315:CLIM_RS02335
uniprot id: B3EG17
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

290315:CLIM RS01550
gene id: 290315:CLIM_RS01550
uniprot id: B3EFB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

290315:CLIM RS00095
gene id: 290315:CLIM_RS00095
uniprot id: B3EDP7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

290315:CLIM RS04270
gene id: 290315:CLIM_RS04270
uniprot id: B3EI99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

290315:CLIM RS02190
gene id: 290315:CLIM_RS02190
uniprot id: B3EFY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

290315:CLIM RS04865
gene id: 290315:CLIM_RS04865
uniprot id: B3EIV3
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

290315:CLIM RS11085
gene id: 290315:CLIM_RS11085
uniprot id: B3EGW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

290315:CLIM RS04995
gene id: 290315:CLIM_RS04995
uniprot id: B3EIX9
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS00715
gene id: 290315:CLIM_RS00715
uniprot id: B3EEA6
names: Similarity
messages: Belongs to the FGGY kinase family.

290315:CLIM RS02795
gene id: 290315:CLIM_RS02795
uniprot id: B3EGK2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

290315:CLIM RS06215
gene id: 290315:CLIM_RS06215
uniprot id: B3ECN4
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS00005
gene id: 290315:CLIM_RS00005
uniprot id: B3EDM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

290315:CLIM RS10675
gene id: 290315:CLIM_RS10675
uniprot id: B3EGN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

290315:CLIM RS10695
gene id: 290315:CLIM_RS10695
uniprot id: B3EGN9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

290315:CLIM RS03175
gene id: 290315:CLIM_RS03175
uniprot id: B3EH31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

290315:CLIM RS03560
gene id: 290315:CLIM_RS03560
uniprot id: B3EHL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

290315:CLIM RS07845
gene id: 290315:CLIM_RS07845
uniprot id: B3EDI8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

290315:CLIM RS11765
gene id: 290315:CLIM_RS11765
uniprot id: B3EHV7
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

290315:CLIM RS04950
gene id: 290315:CLIM_RS04950
uniprot id: B3EIX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

290315:CLIM RS03070
gene id: 290315:CLIM_RS03070
uniprot id: B3EH10
names: Similarity
messages: Belongs to the peptidase S49 family.

290315:CLIM RS01950
gene id: 290315:CLIM_RS01950
uniprot id: B3EFI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

290315:CLIM RS00170
gene id: 290315:CLIM_RS00170
uniprot id: B3EDR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

290315:CLIM RS11160
gene id: 290315:CLIM_RS11160
uniprot id: B3EGY2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

290315:CLIM RS01380
gene id: 290315:CLIM_RS01380
uniprot id: B3EEX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

290315:CLIM RS02065
gene id: 290315:CLIM_RS02065
uniprot id: B3EFW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

290315:CLIM RS00890
gene id: 290315:CLIM_RS00890
uniprot id: B3EED5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

290315:CLIM RS11155
gene id: 290315:CLIM_RS11155
uniprot id: B3EGY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

290315:CLIM RS10745
gene id: 290315:CLIM_RS10745
uniprot id: B3EGQ0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

290315:CLIM RS05425
gene id: 290315:CLIM_RS05425
uniprot id: B3EC82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

290315:CLIM RS01580
gene id: 290315:CLIM_RS01580
uniprot id: B3EFB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

290315:CLIM RS09150
gene id: 290315:CLIM_RS09150
uniprot id: B3EEZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

290315:CLIM RS02050
gene id: 290315:CLIM_RS02050
uniprot id: B3EFV8
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS11210
gene id: 290315:CLIM_RS11210
uniprot id: B3EH93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

290315:CLIM RS10095
gene id: 290315:CLIM_RS10095
uniprot id: B3EFS6
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS07950
gene id: 290315:CLIM_RS07950
uniprot id: B3EDK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

290315:CLIM RS01030
gene id: 290315:CLIM_RS01030
uniprot id: B3EEQ7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

290315:CLIM RS10360
gene id: 290315:CLIM_RS10360
uniprot id: B3EG79
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

290315:CLIM RS12140
gene id: 290315:CLIM_RS12140
uniprot id: B3EI33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

290315:CLIM RS03735
gene id: 290315:CLIM_RS03735
uniprot id: B3EHP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

290315:CLIM RS08310
gene id: 290315:CLIM_RS08310
uniprot id: B3EDY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

290315:CLIM RS03845
gene id: 290315:CLIM_RS03845
uniprot id: B3EHR5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

290315:CLIM RS12590
gene id: 290315:CLIM_RS12590
uniprot id: B3EIL7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

290315:CLIM RS02620
gene id: 290315:CLIM_RS02620
uniprot id: B3EGG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

290315:CLIM RS07725
gene id: 290315:CLIM_RS07725
uniprot id: B3EDG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

290315:CLIM RS10550
gene id: 290315:CLIM_RS10550
uniprot id: B3EGB6
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

290315:CLIM RS11615
gene id: 290315:CLIM_RS11615
uniprot id: B3EHH5
names: Similarity
messages: Belongs to the universal stress protein A family.

290315:CLIM RS01370
gene id: 290315:CLIM_RS01370
uniprot id: B3EEX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

290315:CLIM RS07155
gene id: 290315:CLIM_RS07155
uniprot id: B3ED67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

290315:CLIM RS01785
gene id: 290315:CLIM_RS01785
uniprot id: B3EFF4
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

290315:CLIM RS11150
gene id: 290315:CLIM_RS11150
uniprot id: B3EGY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

290315:CLIM RS02735
gene id: 290315:CLIM_RS02735
uniprot id: B3EGI9
names: Similarity
messages: Belongs to the GroES chaperonin family.

290315:CLIM RS00790
gene id: 290315:CLIM_RS00790
uniprot id: B3EEB5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

290315:CLIM RS03205
gene id: 290315:CLIM_RS03205
uniprot id: B3EH37
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS10820
gene id: 290315:CLIM_RS10820
uniprot id: B3EGR5
names: Similarity
messages: Belongs to the Mg-chelatase subunit H family.

290315:CLIM RS01075
gene id: 290315:CLIM_RS01075
uniprot id: B3EER6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

290315:CLIM RS12555
gene id: 290315:CLIM_RS12555
uniprot id: B3EIL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

290315:CLIM RS00870
gene id: 290315:CLIM_RS00870
uniprot id: B3EED1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

290315:CLIM RS03060
gene id: 290315:CLIM_RS03060
uniprot id: B3EH08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

290315:CLIM RS10070
gene id: 290315:CLIM_RS10070
uniprot id: B3EFS1
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

290315:CLIM RS02175
gene id: 290315:CLIM_RS02175
uniprot id: B3EFY4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

290315:CLIM RS02720
gene id: 290315:CLIM_RS02720
uniprot id: B3EGI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

290315:CLIM RS03200
gene id: 290315:CLIM_RS03200
uniprot id: B3EH36
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

290315:CLIM RS00875
gene id: 290315:CLIM_RS00875
uniprot id: B3EED2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

290315:CLIM RS07955
gene id: 290315:CLIM_RS07955
uniprot id: B3EDK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

290315:CLIM RS10680
gene id: 290315:CLIM_RS10680
uniprot id: B3EGN5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

290315:CLIM RS04320
gene id: 290315:CLIM_RS04320
uniprot id: B3EIA9
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

290315:CLIM RS01390
gene id: 290315:CLIM_RS01390
uniprot id: B3EEX7
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

290315:CLIM RS08045
gene id: 290315:CLIM_RS08045
uniprot id: B3EDM1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS09245
gene id: 290315:CLIM_RS09245
uniprot id: B3EF13
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

290315:CLIM RS11730
gene id: 290315:CLIM_RS11730
uniprot id: B3EHV0
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

290315:CLIM RS04310
gene id: 290315:CLIM_RS04310
uniprot id: B3EIA7
names: Similarity
messages: Belongs to the peptidase A31 family.

290315:CLIM RS10510
gene id: 290315:CLIM_RS10510
uniprot id: B3EGA8
names: Similarity
messages: Belongs to the peptidase S16 family.

290315:CLIM RS11110
gene id: 290315:CLIM_RS11110
uniprot id: B3EGX3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

290315:CLIM RS02625
gene id: 290315:CLIM_RS02625
uniprot id: B3EGH0
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

290315:CLIM RS11100
gene id: 290315:CLIM_RS11100
uniprot id: B3EGX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

290315:CLIM RS09095
gene id: 290315:CLIM_RS09095
uniprot id: B3EEN4
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

290315:CLIM RS10250
gene id: 290315:CLIM_RS10250
uniprot id: B3EG58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

290315:CLIM RS04350
gene id: 290315:CLIM_RS04350
uniprot id: B3EIB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

290315:CLIM RS04670
gene id: 290315:CLIM_RS04670
uniprot id: B3EIR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

290315:CLIM RS06635
gene id: 290315:CLIM_RS06635
uniprot id: B3ECW6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

290315:CLIM RS06730
gene id: 290315:CLIM_RS06730
uniprot id: B3ECY5
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

290315:CLIM RS09820
gene id: 290315:CLIM_RS09820
uniprot id: B3EFM3
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

290315:CLIM RS00835
gene id: 290315:CLIM_RS00835
uniprot id: B3EEC4
names: Similarity
messages: Belongs to the asparaginase 1 family.

290315:CLIM RS05930
gene id: 290315:CLIM_RS05930
uniprot id: B3ECI0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

290315:CLIM RS09955
gene id: 290315:CLIM_RS09955
uniprot id: B3EFP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

290315:CLIM RS12450
gene id: 290315:CLIM_RS12450
uniprot id: B3EIJ2
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

290315:CLIM RS06315
gene id: 290315:CLIM_RS06315
uniprot id: B3ECQ4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS09185
gene id: 290315:CLIM_RS09185
uniprot id: B3EF02
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

290315:CLIM RS04440
gene id: 290315:CLIM_RS04440
uniprot id: B3EID1
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

290315:CLIM RS02035
gene id: 290315:CLIM_RS02035
uniprot id: B3EFV5
names: Similarity
messages: Belongs to the LOG family.

290315:CLIM RS09000
gene id: 290315:CLIM_RS09000
uniprot id: B3EEL5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

290315:CLIM RS11440
gene id: 290315:CLIM_RS11440
uniprot id: B3EHD9
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS10305
gene id: 290315:CLIM_RS10305
uniprot id: B3EG68
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

290315:CLIM RS02060
gene id: 290315:CLIM_RS02060
uniprot id: B3EFW0
names: Similarity
messages: Belongs to the BshC family.

290315:CLIM RS01455
gene id: 290315:CLIM_RS01455
uniprot id: B3EF91
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

290315:CLIM RS08905
gene id: 290315:CLIM_RS08905
uniprot id: B3EEJ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

290315:CLIM RS10310
gene id: 290315:CLIM_RS10310
uniprot id: B3EG69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

290315:CLIM RS00940
gene id: 290315:CLIM_RS00940
uniprot id: B3EEP4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

290315:CLIM RS09900
gene id: 290315:CLIM_RS09900
uniprot id: B3EFN9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

290315:CLIM RS06410
gene id: 290315:CLIM_RS06410
uniprot id: B3ECS3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

290315:CLIM RS06090
gene id: 290315:CLIM_RS06090
uniprot id: B3ECK9
names: Similarity
messages: Belongs to the peptidase S41A family.

290315:CLIM RS02295
gene id: 290315:CLIM_RS02295
uniprot id: B3EG07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

290315:CLIM RS00460
gene id: 290315:CLIM_RS00460
uniprot id: B3EE63
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

290315:CLIM RS08415
gene id: 290315:CLIM_RS08415
uniprot id: B3EE09
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

290315:CLIM RS04355
gene id: 290315:CLIM_RS04355
uniprot id: B3EIB6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

290315:CLIM RS02445
gene id: 290315:CLIM_RS02445
uniprot id: B3EG39
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

290315:CLIM RS03365
gene id: 290315:CLIM_RS03365
uniprot id: B3EH70
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

290315:CLIM RS12540
gene id: 290315:CLIM_RS12540
uniprot id: B3EIK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

290315:CLIM RS04305
gene id: 290315:CLIM_RS04305
uniprot id: B3EIA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

290315:CLIM RS12005
gene id: 290315:CLIM_RS12005
uniprot id: B3EI06
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

290315:CLIM RS11135
gene id: 290315:CLIM_RS11135
uniprot id: B3EGX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

290315:CLIM RS07770
gene id: 290315:CLIM_RS07770
uniprot id: B3EDH5
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS09890
gene id: 290315:CLIM_RS09890
uniprot id: B3EFN7
names: Similarity
messages: Belongs to the CarB family.

290315:CLIM RS06240
gene id: 290315:CLIM_RS06240
uniprot id: B3ECN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

290315:CLIM RS00985
gene id: 290315:CLIM_RS00985
uniprot id: B3EEQ2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

290315:CLIM RS11480
gene id: 290315:CLIM_RS11480
uniprot id: B3EHE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

290315:CLIM RS01655
gene id: 290315:CLIM_RS01655
uniprot id: B3EFD2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

290315:CLIM RS06255
gene id: 290315:CLIM_RS06255
uniprot id: B3ECP2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

290315:CLIM RS06970
gene id: 290315:CLIM_RS06970
uniprot id: B3ED30
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

290315:CLIM RS04385
gene id: 290315:CLIM_RS04385
uniprot id: B3EIC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

290315:CLIM RS02165
gene id: 290315:CLIM_RS02165
uniprot id: B3EFY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

290315:CLIM RS08120
gene id: 290315:CLIM_RS08120
uniprot id: B3EDV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

290315:CLIM RS05830
gene id: 290315:CLIM_RS05830
uniprot id: B3ECG0
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS11840
gene id: 290315:CLIM_RS11840
uniprot id: B3EHX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

290315:CLIM RS01355
gene id: 290315:CLIM_RS01355
uniprot id: B3EEX0
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

290315:CLIM RS03195
gene id: 290315:CLIM_RS03195
uniprot id: B3EH35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

290315:CLIM RS06000
gene id: 290315:CLIM_RS06000
uniprot id: B3ECJ2
names: Similarity
messages: Belongs to the HdrA family.

290315:CLIM RS04495
gene id: 290315:CLIM_RS04495
uniprot id: B3EIN1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

290315:CLIM RS01150
gene id: 290315:CLIM_RS01150
uniprot id: B3EET2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

290315:CLIM RS10875
gene id: 290315:CLIM_RS10875
uniprot id: B3EGS5
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

290315:CLIM RS01775
gene id: 290315:CLIM_RS01775
uniprot id: B3EFF2
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

290315:CLIM RS04140
gene id: 290315:CLIM_RS04140
uniprot id: B3EI76
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

290315:CLIM RS12485
gene id: 290315:CLIM_RS12485
uniprot id: B3EIJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has four main subunits: a(1), b(1), b'(1) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta, b and b' chains.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

290315:CLIM RS10775
gene id: 290315:CLIM_RS10775
uniprot id: B3EGQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BChl C/E-binding protein family.
messages: Component of the photosynthetic apparatus.
messages: chlorosome envelope

290315:CLIM RS03390
gene id: 290315:CLIM_RS03390
uniprot id: B3EH76
names: Similarity
messages: Belongs to the ModE family.

290315:CLIM RS05475
gene id: 290315:CLIM_RS05475
uniprot id: B3EC92
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

290315:CLIM RS12640
gene id: 290315:CLIM_RS12640
uniprot id: B3EIM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

290315:CLIM RS00065
gene id: 290315:CLIM_RS00065
uniprot id: B3EDP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

290315:CLIM RS01360
gene id: 290315:CLIM_RS01360
uniprot id: B3EEX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

290315:CLIM RS02100
gene id: 290315:CLIM_RS02100
uniprot id: B3EFW8
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

290315:CLIM RS09840
gene id: 290315:CLIM_RS09840
uniprot id: B3EFM7
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

290315:CLIM RS10335
gene id: 290315:CLIM_RS10335
uniprot id: B3EG74
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

290315:CLIM RS07135
gene id: 290315:CLIM_RS07135
uniprot id: B3ED63
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS01990
gene id: 290315:CLIM_RS01990
uniprot id: B3EFU6
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

290315:CLIM RS04035
gene id: 290315:CLIM_RS04035
uniprot id: B3EI54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

290315:CLIM RS05455
gene id: 290315:CLIM_RS05455
uniprot id: B3EC88
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

290315:CLIM RS01525
gene id: 290315:CLIM_RS01525
uniprot id: B3EFA6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

290315:CLIM RS07440
gene id: 290315:CLIM_RS07440
uniprot id: B3EDB6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

290315:CLIM RS03420
gene id: 290315:CLIM_RS03420
uniprot id: B3EH82
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

290315:CLIM RS04395
gene id: 290315:CLIM_RS04395
uniprot id: B3EIC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

290315:CLIM RS09350
gene id: 290315:CLIM_RS09350
uniprot id: B3EF34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

290315:CLIM RS10735
gene id: 290315:CLIM_RS10735
uniprot id: B3EGP8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

290315:CLIM RS09995
gene id: 290315:CLIM_RS09995
uniprot id: B3EFQ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

290315:CLIM RS08710
gene id: 290315:CLIM_RS08710
uniprot id: B3EEF9
names: Similarity
messages: Belongs to the UPF0047 family.

290315:CLIM RS02120
gene id: 290315:CLIM_RS02120
uniprot id: B3EFX2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

290315:CLIM RS12565
gene id: 290315:CLIM_RS12565
uniprot id: B3EIL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

290315:CLIM RS00100
gene id: 290315:CLIM_RS00100
uniprot id: B3EDP8
names: Similarity
messages: Belongs to the peptidase S41A family.

290315:CLIM RS04370
gene id: 290315:CLIM_RS04370
uniprot id: B3EIB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

290315:CLIM RS06990
gene id: 290315:CLIM_RS06990
uniprot id: B3ED34
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

290315:CLIM RS05005
gene id: 290315:CLIM_RS05005
uniprot id: B3EBZ7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

290315:CLIM RS10255
gene id: 290315:CLIM_RS10255
uniprot id: B3EG59
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

290315:CLIM RS06775
gene id: 290315:CLIM_RS06775
uniprot id: B3ECZ3
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

290315:CLIM RS08895
gene id: 290315:CLIM_RS08895
uniprot id: B3EEJ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS01600
gene id: 290315:CLIM_RS01600
uniprot id: B3EFC1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

290315:CLIM RS03235
gene id: 290315:CLIM_RS03235
uniprot id: B3EH43
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS01880
gene id: 290315:CLIM_RS01880
uniprot id: B3EFH2
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS09240
gene id: 290315:CLIM_RS09240
uniprot id: B3EF12
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

290315:CLIM RS05095
gene id: 290315:CLIM_RS05095
uniprot id: B3EC15
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

290315:CLIM RS08440
gene id: 290315:CLIM_RS08440
uniprot id: B3EE14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

290315:CLIM RS00035
gene id: 290315:CLIM_RS00035
uniprot id: B3EDN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

290315:CLIM RS04400
gene id: 290315:CLIM_RS04400
uniprot id: B3EIC5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

290315:CLIM RS07665
gene id: 290315:CLIM_RS07665
uniprot id: B3EDF4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

290315:CLIM RS02695
gene id: 290315:CLIM_RS02695
uniprot id: B3EGI2
names: Cofactor
names: Similarity
messages: Belongs to the PdaD family.
messages: Binds 1 pyruvoyl group covalently per subunit.

290315:CLIM RS09760
gene id: 290315:CLIM_RS09760
uniprot id: B3EFL2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

290315:CLIM RS03975
gene id: 290315:CLIM_RS03975
uniprot id: B3EHU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

290315:CLIM RS04915
gene id: 290315:CLIM_RS04915
uniprot id: B3EIW3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

290315:CLIM RS08390
gene id: 290315:CLIM_RS08390
uniprot id: B3EE04
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

290315:CLIM RS11725
gene id: 290315:CLIM_RS11725
uniprot id: B3EHU9
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

290315:CLIM RS08330
gene id: 290315:CLIM_RS08330
uniprot id: B3EDZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

290315:CLIM RS01055
gene id: 290315:CLIM_RS01055
uniprot id: B3EER2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

290315:CLIM RS10915
gene id: 290315:CLIM_RS10915
uniprot id: B3EGT3
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS08530
gene id: 290315:CLIM_RS08530
uniprot id: B3EE33
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

290315:CLIM RS09255
gene id: 290315:CLIM_RS09255
uniprot id: B3EF15
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

290315:CLIM RS07150
gene id: 290315:CLIM_RS07150
uniprot id: B3ED66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

290315:CLIM RS00690
gene id: 290315:CLIM_RS00690
uniprot id: B3EEA1
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

290315:CLIM RS04300
gene id: 290315:CLIM_RS04300
uniprot id: B3EIA5
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

290315:CLIM RS08975
gene id: 290315:CLIM_RS08975
uniprot id: B3EEL0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

290315:CLIM RS05305
gene id: 290315:CLIM_RS05305
uniprot id: B3EC58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

290315:CLIM RS05860
gene id: 290315:CLIM_RS05860
uniprot id: B3ECG6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

290315:CLIM RS10315
gene id: 290315:CLIM_RS10315
uniprot id: B3EG70
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS07835
gene id: 290315:CLIM_RS07835
uniprot id: B3EDI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

290315:CLIM RS07540
gene id: 290315:CLIM_RS07540
uniprot id: B3EDD2
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

290315:CLIM RS04245
gene id: 290315:CLIM_RS04245
uniprot id: B3EI94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

290315:CLIM RS05300
gene id: 290315:CLIM_RS05300
uniprot id: B3EC57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

290315:CLIM RS02355
gene id: 290315:CLIM_RS02355
uniprot id: B3EG21
names: Subcellular Location Annotation
messages: Membrane

290315:CLIM RS03040
gene id: 290315:CLIM_RS03040
uniprot id: B3EH04
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290315:CLIM RS10320
gene id: 290315:CLIM_RS10320
uniprot id: B3EG71
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

290315:CLIM RS10265
gene id: 290315:CLIM_RS10265
uniprot id: B3EG61
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

290315:CLIM RS00930
gene id: 290315:CLIM_RS00930
uniprot id: B3EEP3
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

290315:CLIM RS06075
gene id: 290315:CLIM_RS06075
uniprot id: B3ECK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

290315:CLIM RS01855
gene id: 290315:CLIM_RS01855
uniprot id: B3EFG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

290315:CLIM RS02285
gene id: 290315:CLIM_RS02285
uniprot id: B3EG05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

290315:CLIM RS10620
gene id: 290315:CLIM_RS10620
uniprot id: B3EGC8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

290315:CLIM RS02365
gene id: 290315:CLIM_RS02365
uniprot id: B3EG23
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

290315:CLIM RS01815
gene id: 290315:CLIM_RS01815
uniprot id: B3EFG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

290315:CLIM RS12125
gene id: 290315:CLIM_RS12125
uniprot id: B3EI30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

290315:CLIM RS05150
gene id: 290315:CLIM_RS05150
uniprot id: B3EC23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

290315:CLIM RS09665
gene id: 290315:CLIM_RS09665
uniprot id: B3EFJ4
names: Similarity
messages: Belongs to the peptidase S8 family.