28135:EL210 RS06695
gene id: 28135:EL210_RS06695
uniprot id: A0A3S4X767
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

28135:EL210 RS04050
gene id: 28135:EL210_RS04050
uniprot id: A0A3S4V8W2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

28135:EL210 RS07690
gene id: 28135:EL210_RS07690
uniprot id: A0A448L6G7
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS10520
gene id: 28135:EL210_RS10520
uniprot id: A0A3S4TG01
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

28135:EL210 RS03735
gene id: 28135:EL210_RS03735
uniprot id: A0A448L494
names: Similarity
messages: Belongs to the SusD family.

28135:EL210 RS07990
gene id: 28135:EL210_RS07990
uniprot id: A0A3S5EPB6
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

28135:EL210 RS11405
gene id: 28135:EL210_RS11405
uniprot id: A0A3S4VB29
names: Similarity
messages: Belongs to the SusD family.

28135:EL210 RS01835
gene id: 28135:EL210_RS01835
uniprot id: A0A448L375
names: Similarity
messages: Belongs to the SusD family.

28135:EL210 RS00255
gene id: 28135:EL210_RS00255
uniprot id: A0A3S4V7Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

28135:EL210 RS10740
gene id: 28135:EL210_RS10740
uniprot id: A0A448L8H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

28135:EL210 RS02445
gene id: 28135:EL210_RS02445
uniprot id: A0A3S4TDD4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

28135:EL210 RS05410
gene id: 28135:EL210_RS05410
uniprot id: A0A448L563
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

28135:EL210 RS03395
gene id: 28135:EL210_RS03395
uniprot id: A0A448L424
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

28135:EL210 RS10530
gene id: 28135:EL210_RS10530
uniprot id: A0A3S4VAT1
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS12455
gene id: 28135:EL210_RS12455
uniprot id: A0A448L959
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS07475
gene id: 28135:EL210_RS07475
uniprot id: A0A448L6P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

28135:EL210 RS00175
gene id: 28135:EL210_RS00175
uniprot id: A0A448L260
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

28135:EL210 RS08820
gene id: 28135:EL210_RS08820
uniprot id: A0A448L751
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

28135:EL210 RS11865
gene id: 28135:EL210_RS11865
uniprot id: A0A3S5EPG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

28135:EL210 RS08655
gene id: 28135:EL210_RS08655
uniprot id: A0A448L785
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

28135:EL210 RS08665
gene id: 28135:EL210_RS08665
uniprot id: A0A448L748
names: Similarity
messages: Belongs to the asparaginase 1 family.

28135:EL210 RS07295
gene id: 28135:EL210_RS07295
uniprot id: A0A3S4TBI0
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

28135:EL210 RS04940
gene id: 28135:EL210_RS04940
uniprot id: A0A448L4Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS00325
gene id: 28135:EL210_RS00325
uniprot id: A0A3S4T3Q3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

28135:EL210 RS12100
gene id: 28135:EL210_RS12100
uniprot id: A0A448L906
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

28135:EL210 RS02900
gene id: 28135:EL210_RS02900
uniprot id: A0A448L3S3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

28135:EL210 RS07305
gene id: 28135:EL210_RS07305
uniprot id: A0A3S4X2A0
names: Similarity
messages: Belongs to the SusD family.

28135:EL210 RS13140
gene id: 28135:EL210_RS13140
uniprot id: A0A448L9K4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28135:EL210 RS03345
gene id: 28135:EL210_RS03345
uniprot id: A0A448L414
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

28135:EL210 RS03525
gene id: 28135:EL210_RS03525
uniprot id: A0A448L460
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

28135:EL210 RS12330
gene id: 28135:EL210_RS12330
uniprot id: A0A3S4UNF4
names: Similarity
messages: Belongs to the UPF0758 family.

28135:EL210 RS04185
gene id: 28135:EL210_RS04185
uniprot id: A0A448L4G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

28135:EL210 RS12315
gene id: 28135:EL210_RS12315
uniprot id: A0A3S4TD19
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

28135:EL210 RS11560
gene id: 28135:EL210_RS11560
uniprot id: A0A448L8R7
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

28135:EL210 RS00490
gene id: 28135:EL210_RS00490
uniprot id: A0A3S4T3S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS01945
gene id: 28135:EL210_RS01945
uniprot id: A0A3S4X5K5
names: Similarity
messages: Belongs to the peptidase C10 family.

28135:EL210 RS05205
gene id: 28135:EL210_RS05205
uniprot id: A0A448L508
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

28135:EL210 RS13130
gene id: 28135:EL210_RS13130
uniprot id: A0A3S4X965
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

28135:EL210 RS11055
gene id: 28135:EL210_RS11055
uniprot id: A0A3S5EPE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

28135:EL210 RS10610
gene id: 28135:EL210_RS10610
uniprot id: A0A3S4UMX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

28135:EL210 RS06615
gene id: 28135:EL210_RS06615
uniprot id: A0A3S4TXA5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS09285
gene id: 28135:EL210_RS09285
uniprot id: A0A448L7D6
names: Similarity
messages: Belongs to the TrpF family.

28135:EL210 RS09035
gene id: 28135:EL210_RS09035
uniprot id: A0A3S4TXZ8
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS07020
gene id: 28135:EL210_RS07020
uniprot id: A0A3S4TEZ4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

28135:EL210 RS04125
gene id: 28135:EL210_RS04125
uniprot id: A0A448L4H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

28135:EL210 RS07910
gene id: 28135:EL210_RS07910
uniprot id: A0A3S4TBP4
names: Similarity
messages: Belongs to the pyruvate kinase family.

28135:EL210 RS03925
gene id: 28135:EL210_RS03925
uniprot id: A0A448L4C3
names: Similarity
messages: Belongs to the YicC/YloC family.

28135:EL210 RS06830
gene id: 28135:EL210_RS06830
uniprot id: A0A448L601
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

28135:EL210 RS03795
gene id: 28135:EL210_RS03795
uniprot id: A0A3S4X141
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28135:EL210 RS01480
gene id: 28135:EL210_RS01480
uniprot id: A0A448L2Z7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

28135:EL210 RS12735
gene id: 28135:EL210_RS12735
uniprot id: A0A448L9D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

28135:EL210 RS01940
gene id: 28135:EL210_RS01940
uniprot id: A0A448L383
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

28135:EL210 RS04245
gene id: 28135:EL210_RS04245
uniprot id: A0A3S4X190
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

28135:EL210 RS02285
gene id: 28135:EL210_RS02285
uniprot id: A0A448L3D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS10160
gene id: 28135:EL210_RS10160
uniprot id: A0A448L7Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

28135:EL210 RS00260
gene id: 28135:EL210_RS00260
uniprot id: A0A3S4T0A9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

28135:EL210 RS00210
gene id: 28135:EL210_RS00210
uniprot id: A0A3S4T928
names: Similarity
messages: Belongs to the peptidase C1 family.

28135:EL210 RS01560
gene id: 28135:EL210_RS01560
uniprot id: A0A3S4V837
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

28135:EL210 RS03520
gene id: 28135:EL210_RS03520
uniprot id: A0A448L446
names: Similarity
messages: Belongs to the UPF0246 family.

28135:EL210 RS12560
gene id: 28135:EL210_RS12560
uniprot id: A0A3S4TGN7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

28135:EL210 RS04675
gene id: 28135:EL210_RS04675
uniprot id: A0A448L4U0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

28135:EL210 RS09240
gene id: 28135:EL210_RS09240
uniprot id: A0A448L7L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

28135:EL210 RS02135
gene id: 28135:EL210_RS02135
uniprot id: A0A448L3A0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

28135:EL210 RS12250
gene id: 28135:EL210_RS12250
uniprot id: A0A448L939
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

28135:EL210 RS08585
gene id: 28135:EL210_RS08585
uniprot id: A0A448L6Y5
names: Similarity
messages: Belongs to the CarB family.

28135:EL210 RS10870
gene id: 28135:EL210_RS10870
uniprot id: A0A3S4X388
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

28135:EL210 RS01680
gene id: 28135:EL210_RS01680
uniprot id: A0A3S4UKD2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

28135:EL210 RS01145
gene id: 28135:EL210_RS01145
uniprot id: A0A3S4X0C3
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS08890
gene id: 28135:EL210_RS08890
uniprot id: A0A448L761
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

28135:EL210 RS12170
gene id: 28135:EL210_RS12170
uniprot id: A0A448L941
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

28135:EL210 RS04070
gene id: 28135:EL210_RS04070
uniprot id: A0A448L4E9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

28135:EL210 RS11125
gene id: 28135:EL210_RS11125
uniprot id: A0A3S4TCN6
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS07565
gene id: 28135:EL210_RS07565
uniprot id: A0A3S4V9Z6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

28135:EL210 RS02500
gene id: 28135:EL210_RS02500
uniprot id: A0A448L3I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

28135:EL210 RS07615
gene id: 28135:EL210_RS07615
uniprot id: A0A3S4T618
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

28135:EL210 RS07600
gene id: 28135:EL210_RS07600
uniprot id: A0A3S4TBL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

28135:EL210 RS09265
gene id: 28135:EL210_RS09265
uniprot id: A0A3S4VAF8
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS08435
gene id: 28135:EL210_RS08435
uniprot id: A0A3S4T6A9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

28135:EL210 RS04805
gene id: 28135:EL210_RS04805
uniprot id: A0A448L4V9
names: Similarity
messages: Belongs to the disproportionating enzyme family.

28135:EL210 RS05080
gene id: 28135:EL210_RS05080
uniprot id: A0A3S4V976
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

28135:EL210 RS06785
gene id: 28135:EL210_RS06785
uniprot id: A0A3S5EPA2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

28135:EL210 RS06790
gene id: 28135:EL210_RS06790
uniprot id: A0A448L636
names: Similarity
messages: Belongs to the Skp family.

28135:EL210 RS04510
gene id: 28135:EL210_RS04510
uniprot id: A0A448L4P2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS06445
gene id: 28135:EL210_RS06445
uniprot id: A0A3S4TB75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

28135:EL210 RS07645
gene id: 28135:EL210_RS07645
uniprot id: A0A3S4UM33
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

28135:EL210 RS04935
gene id: 28135:EL210_RS04935
uniprot id: A0A3S4UL91
names: Similarity
messages: Belongs to the SusD family.

28135:EL210 RS11620
gene id: 28135:EL210_RS11620
uniprot id: A0A3S4X3G5
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

28135:EL210 RS08285
gene id: 28135:EL210_RS08285
uniprot id: A0A3S4UM94
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

28135:EL210 RS08825
gene id: 28135:EL210_RS08825
uniprot id: A0A448L737
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

28135:EL210 RS07980
gene id: 28135:EL210_RS07980
uniprot id: A0A3S4X7K0
names: Similarity
messages: Belongs to the aldose epimerase family.

28135:EL210 RS07370
gene id: 28135:EL210_RS07370
uniprot id: A0A448L6H2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS07535
gene id: 28135:EL210_RS07535
uniprot id: A0A448L6D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

28135:EL210 RS07805
gene id: 28135:EL210_RS07805
uniprot id: A0A3S4T637
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

28135:EL210 RS02585
gene id: 28135:EL210_RS02585
uniprot id: A0A448L3K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

28135:EL210 RS03990
gene id: 28135:EL210_RS03990
uniprot id: A0A448L4F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

28135:EL210 RS00485
gene id: 28135:EL210_RS00485
uniprot id: A0A3S4T959
names: Similarity
messages: Belongs to the SusD family.

28135:EL210 RS09380
gene id: 28135:EL210_RS09380
uniprot id: A0A3S4T6K5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

28135:EL210 RS08155
gene id: 28135:EL210_RS08155
uniprot id: A0A3S5EPB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

28135:EL210 RS11930
gene id: 28135:EL210_RS11930
uniprot id: A0A448L8X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

28135:EL210 RS11825
gene id: 28135:EL210_RS11825
uniprot id: A0A3S4VB87
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

28135:EL210 RS11250
gene id: 28135:EL210_RS11250
uniprot id: A0A3S4T3M9
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS08315
gene id: 28135:EL210_RS08315
uniprot id: A0A448L6S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

28135:EL210 RS12675
gene id: 28135:EL210_RS12675
uniprot id: A0A3S4X917
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

28135:EL210 RS04315
gene id: 28135:EL210_RS04315
uniprot id: A0A448L4K2
names: Similarity
messages: Belongs to the Skp family.

28135:EL210 RS13160
gene id: 28135:EL210_RS13160
uniprot id: A0A448L9N6
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS12145
gene id: 28135:EL210_RS12145
uniprot id: A0A3S5EPG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

28135:EL210 RS02915
gene id: 28135:EL210_RS02915
uniprot id: A0A3S4T122
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

28135:EL210 RS12695
gene id: 28135:EL210_RS12695
uniprot id: A0A3S4TD63
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS09155
gene id: 28135:EL210_RS09155
uniprot id: A0A448L7I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

28135:EL210 RS05225
gene id: 28135:EL210_RS05225
uniprot id: A0A3S4T1P3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

28135:EL210 RS10535
gene id: 28135:EL210_RS10535
uniprot id: A0A3S4T3F7
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS10830
gene id: 28135:EL210_RS10830
uniprot id: A0A3S4T3I2
names: Similarity
messages: Belongs to the bacteroidetes fimbrillin superfamily. FimB/Mfa2 family.

28135:EL210 RS06655
gene id: 28135:EL210_RS06655
uniprot id: A0A3S4T5Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

28135:EL210 RS09775
gene id: 28135:EL210_RS09775
uniprot id: A0A448L7Q5
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

28135:EL210 RS12810
gene id: 28135:EL210_RS12810
uniprot id: A0A448L9F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

28135:EL210 RS11885
gene id: 28135:EL210_RS11885
uniprot id: A0A3S4T7A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

28135:EL210 RS11050
gene id: 28135:EL210_RS11050
uniprot id: A0A3S4X8H4
names: Similarity
messages: Belongs to the MreC family.

28135:EL210 RS07490
gene id: 28135:EL210_RS07490
uniprot id: A0A3S4X7F3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

28135:EL210 RS08875
gene id: 28135:EL210_RS08875
uniprot id: A0A3S4X7U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

28135:EL210 RS11745
gene id: 28135:EL210_RS11745
uniprot id: A0A3S4TCW2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

28135:EL210 RS04680
gene id: 28135:EL210_RS04680
uniprot id: A0A448L4T8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

28135:EL210 RS02975
gene id: 28135:EL210_RS02975
uniprot id: A0A3S4UKQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

28135:EL210 RS06990
gene id: 28135:EL210_RS06990
uniprot id: A0A448L6B9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

28135:EL210 RS04715
gene id: 28135:EL210_RS04715
uniprot id: A0A3S4T518
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

28135:EL210 RS10885
gene id: 28135:EL210_RS10885
uniprot id: A0A448L8C0
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

28135:EL210 RS06640
gene id: 28135:EL210_RS06640
uniprot id: A0A448L5X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

28135:EL210 RS00950
gene id: 28135:EL210_RS00950
uniprot id: A0A448L2Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS13115
gene id: 28135:EL210_RS13115
uniprot id: A0A3S4T492
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS01350
gene id: 28135:EL210_RS01350
uniprot id: A0A448L2V0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

28135:EL210 RS12380
gene id: 28135:EL210_RS12380
uniprot id: A0A448L9D0
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

28135:EL210 RS01620
gene id: 28135:EL210_RS01620
uniprot id: A0A3S4X0G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

28135:EL210 RS03770
gene id: 28135:EL210_RS03770
uniprot id: A0A3S4X652
names: Similarity
messages: Belongs to the Vsr family.

28135:EL210 RS08920
gene id: 28135:EL210_RS08920
uniprot id: A0A448L7A3
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS12505
gene id: 28135:EL210_RS12505
uniprot id: A0A448L969
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

28135:EL210 RS11015
gene id: 28135:EL210_RS11015
uniprot id: A0A3S4UN14
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS04635
gene id: 28135:EL210_RS04635
uniprot id: A0A3S4UL56
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS09295
gene id: 28135:EL210_RS09295
uniprot id: A0A3S5EPD0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

28135:EL210 RS05840
gene id: 28135:EL210_RS05840
uniprot id: A0A3S4T5E0
names: Similarity
messages: Belongs to the heat shock protein 90 family.

28135:EL210 RS11680
gene id: 28135:EL210_RS11680
uniprot id: A0A448L8Q6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

28135:EL210 RS00995
gene id: 28135:EL210_RS00995
uniprot id: A0A3S4T0I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS02960
gene id: 28135:EL210_RS02960
uniprot id: A0A3S4T4H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

28135:EL210 RS08120
gene id: 28135:EL210_RS08120
uniprot id: A0A3S4TXR0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

28135:EL210 RS04040
gene id: 28135:EL210_RS04040
uniprot id: A0A448L4G4
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

28135:EL210 RS13120
gene id: 28135:EL210_RS13120
uniprot id: A0A448L9Y7
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

28135:EL210 RS11840
gene id: 28135:EL210_RS11840
uniprot id: A0A448L8V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

28135:EL210 RS04020
gene id: 28135:EL210_RS04020
uniprot id: A0A3S4TAB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

28135:EL210 RS02390
gene id: 28135:EL210_RS02390
uniprot id: A0A448L3G3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

28135:EL210 RS03090
gene id: 28135:EL210_RS03090
uniprot id: A0A448L3U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

28135:EL210 RS10500
gene id: 28135:EL210_RS10500
uniprot id: A0A448L841
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

28135:EL210 RS02230
gene id: 28135:EL210_RS02230
uniprot id: A0A448L3E1
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

28135:EL210 RS04720
gene id: 28135:EL210_RS04720
uniprot id: A0A3S4X1E1
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

28135:EL210 RS07640
gene id: 28135:EL210_RS07640
uniprot id: A0A448L6E4
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS12640
gene id: 28135:EL210_RS12640
uniprot id: A0A448L992
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

28135:EL210 RS03180
gene id: 28135:EL210_RS03180
uniprot id: A0A3S4UKS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

28135:EL210 RS07380
gene id: 28135:EL210_RS07380
uniprot id: A0A3S4V9Y1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

28135:EL210 RS09575
gene id: 28135:EL210_RS09575
uniprot id: A0A448L7T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

28135:EL210 RS07075
gene id: 28135:EL210_RS07075
uniprot id: A0A3S4V9U6
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS01475
gene id: 28135:EL210_RS01475
uniprot id: A0A3S4TVT9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

28135:EL210 RS00740
gene id: 28135:EL210_RS00740
uniprot id: A0A3S4T987
names: Similarity
messages: Belongs to the SusD family.

28135:EL210 RS07610
gene id: 28135:EL210_RS07610
uniprot id: A0A448L6M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

28135:EL210 RS12630
gene id: 28135:EL210_RS12630
uniprot id: A0A3S4TGQ4
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

28135:EL210 RS03760
gene id: 28135:EL210_RS03760
uniprot id: A0A448L490
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

28135:EL210 RS04115
gene id: 28135:EL210_RS04115
uniprot id: A0A448L4G3
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.

28135:EL210 RS05070
gene id: 28135:EL210_RS05070
uniprot id: A0A448L514
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

28135:EL210 RS00310
gene id: 28135:EL210_RS00310
uniprot id: A0A448L2E0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

28135:EL210 RS06950
gene id: 28135:EL210_RS06950
uniprot id: A0A448L626
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

28135:EL210 RS09945
gene id: 28135:EL210_RS09945
uniprot id: A0A3S4TCB2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

28135:EL210 RS08145
gene id: 28135:EL210_RS08145
uniprot id: A0A3S4X7M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

28135:EL210 RS07675
gene id: 28135:EL210_RS07675
uniprot id: A0A448L6G2
names: Similarity
messages: Belongs to the FBPase class 3 family.

28135:EL210 RS10930
gene id: 28135:EL210_RS10930
uniprot id: A0A448L8B7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

28135:EL210 RS01915
gene id: 28135:EL210_RS01915
uniprot id: A0A448L350
names: Similarity
messages: Belongs to the peptidase S41A family.

28135:EL210 RS07950
gene id: 28135:EL210_RS07950
uniprot id: A0A3S4T2I1
names: Similarity
messages: Belongs to the threonine synthase family.

28135:EL210 RS04150
gene id: 28135:EL210_RS04150
uniprot id: A0A3S4TDY8
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS11025
gene id: 28135:EL210_RS11025
uniprot id: A0A448L8G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

28135:EL210 RS02580
gene id: 28135:EL210_RS02580
uniprot id: A0A448L3K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

28135:EL210 RS13110
gene id: 28135:EL210_RS13110
uniprot id: A0A3S4VBL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

28135:EL210 RS12430
gene id: 28135:EL210_RS12430
uniprot id: A0A3S4TD29
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

28135:EL210 RS07965
gene id: 28135:EL210_RS07965
uniprot id: A0A448L6N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

28135:EL210 RS06200
gene id: 28135:EL210_RS06200
uniprot id: A0A448L5N2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

28135:EL210 RS10955
gene id: 28135:EL210_RS10955
uniprot id: A0A3S5EPE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

28135:EL210 RS13225
gene id: 28135:EL210_RS13225
uniprot id: A0A3S4T4A2
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

28135:EL210 RS06240
gene id: 28135:EL210_RS06240
uniprot id: A0A3S4T201
names: Cofactor
messages: Binds 1 zinc ion per subunit.

28135:EL210 RS07055
gene id: 28135:EL210_RS07055
uniprot id: A0A3S4TBF1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

28135:EL210 RS06530
gene id: 28135:EL210_RS06530
uniprot id: A0A448L5V0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS13380
gene id: 28135:EL210_RS13380
uniprot id: A0A448L9R0
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

28135:EL210 RS02145
gene id: 28135:EL210_RS02145
uniprot id: A0A448L3C6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

28135:EL210 RS06805
gene id: 28135:EL210_RS06805
uniprot id: A0A3S4X239
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

28135:EL210 RS07210
gene id: 28135:EL210_RS07210
uniprot id: A0A3S4X289
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

28135:EL210 RS08815
gene id: 28135:EL210_RS08815
uniprot id: A0A448L743
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

28135:EL210 RS09085
gene id: 28135:EL210_RS09085
uniprot id: A0A448L7D4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS10790
gene id: 28135:EL210_RS10790
uniprot id: A0A448L8I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

28135:EL210 RS09130
gene id: 28135:EL210_RS09130
uniprot id: A0A3S4TY08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS08135
gene id: 28135:EL210_RS08135
uniprot id: A0A448L6Q6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

28135:EL210 RS05165
gene id: 28135:EL210_RS05165
uniprot id: A0A3S5EP83
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

28135:EL210 RS08310
gene id: 28135:EL210_RS08310
uniprot id: A0A448L6R2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

28135:EL210 RS12475
gene id: 28135:EL210_RS12475
uniprot id: A0A448L9J6
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

28135:EL210 RS11595
gene id: 28135:EL210_RS11595
uniprot id: A0A448L908
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

28135:EL210 RS10625
gene id: 28135:EL210_RS10625
uniprot id: A0A448L874
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

28135:EL210 RS02110
gene id: 28135:EL210_RS02110
uniprot id: A0A3S4TDA5
names: Similarity
messages: Belongs to the LOG family.

28135:EL210 RS10650
gene id: 28135:EL210_RS10650
uniprot id: A0A448L872
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

28135:EL210 RS07265
gene id: 28135:EL210_RS07265
uniprot id: A0A3S4V9W3
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.
messages: Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose.

28135:EL210 RS00205
gene id: 28135:EL210_RS00205
uniprot id: A0A3S5EP31
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS03140
gene id: 28135:EL210_RS03140
uniprot id: A0A3S5EP62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS11130
gene id: 28135:EL210_RS11130
uniprot id: A0A3S4T6Z8
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS05665
gene id: 28135:EL210_RS05665
uniprot id: A0A448L5D2
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS07855
gene id: 28135:EL210_RS07855
uniprot id: A0A3S4VA20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

28135:EL210 RS03425
gene id: 28135:EL210_RS03425
uniprot id: A0A448L423
names: Similarity
messages: Belongs to the SusD family.

28135:EL210 RS06865
gene id: 28135:EL210_RS06865
uniprot id: A0A3S4X246
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

28135:EL210 RS09310
gene id: 28135:EL210_RS09310
uniprot id: A0A448L7I7
names: Similarity
messages: Belongs to the SusD family.

28135:EL210 RS00410
gene id: 28135:EL210_RS00410
uniprot id: A0A448L2G5
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

28135:EL210 RS11790
gene id: 28135:EL210_RS11790
uniprot id: A0A3S4TYY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

28135:EL210 RS08670
gene id: 28135:EL210_RS08670
uniprot id: A0A3S4TBW5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

28135:EL210 RS02375
gene id: 28135:EL210_RS02375
uniprot id: A0A448L3G1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

28135:EL210 RS03370
gene id: 28135:EL210_RS03370
uniprot id: A0A3S4X0Y9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

28135:EL210 RS07655
gene id: 28135:EL210_RS07655
uniprot id: A0A3S4TF64
names: Similarity
messages: Belongs to the aspartokinase family.

28135:EL210 RS00195
gene id: 28135:EL210_RS00195
uniprot id: A0A448L2D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS04310
gene id: 28135:EL210_RS04310
uniprot id: A0A3S4T4X7
names: Similarity
messages: Belongs to the Skp family.

28135:EL210 RS05430
gene id: 28135:EL210_RS05430
uniprot id: A0A448L577
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

28135:EL210 RS04170
gene id: 28135:EL210_RS04170
uniprot id: A0A3S4T1E9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

28135:EL210 RS08650
gene id: 28135:EL210_RS08650
uniprot id: A0A448L715
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

28135:EL210 RS03975
gene id: 28135:EL210_RS03975
uniprot id: A0A448L4C5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS01005
gene id: 28135:EL210_RS01005
uniprot id: A0A448L2S8
names: Similarity
messages: Belongs to the SusD family.

28135:EL210 RS11315
gene id: 28135:EL210_RS11315
uniprot id: A0A448L8J5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

28135:EL210 RS11830
gene id: 28135:EL210_RS11830
uniprot id: A0A448L8V1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

28135:EL210 RS13065
gene id: 28135:EL210_RS13065
uniprot id: A0A3S4TZA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

28135:EL210 RS04880
gene id: 28135:EL210_RS04880
uniprot id: A0A448L4W9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

28135:EL210 RS07940
gene id: 28135:EL210_RS07940
uniprot id: A0A3S4TF94
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

28135:EL210 RS03850
gene id: 28135:EL210_RS03850
uniprot id: A0A448L4B5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

28135:EL210 RS06710
gene id: 28135:EL210_RS06710
uniprot id: A0A3S4TBB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

28135:EL210 RS01315
gene id: 28135:EL210_RS01315
uniprot id: A0A448L2Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

28135:EL210 RS12175
gene id: 28135:EL210_RS12175
uniprot id: A0A3S4X3N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

28135:EL210 RS11905
gene id: 28135:EL210_RS11905
uniprot id: A0A448L8Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

28135:EL210 RS04580
gene id: 28135:EL210_RS04580
uniprot id: A0A448L4P7
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

28135:EL210 RS01260
gene id: 28135:EL210_RS01260
uniprot id: A0A3S4T0L9
names: Similarity
messages: Belongs to the peptidase M24B family.

28135:EL210 RS06460
gene id: 28135:EL210_RS06460
uniprot id: A0A3S4ULQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

28135:EL210 RS08970
gene id: 28135:EL210_RS08970
uniprot id: A0A3S4T6F4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

28135:EL210 RS13190
gene id: 28135:EL210_RS13190
uniprot id: A0A448L9L6
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS09040
gene id: 28135:EL210_RS09040
uniprot id: A0A448L788
names: Similarity
messages: Belongs to the DEAD box helicase family.

28135:EL210 RS01600
gene id: 28135:EL210_RS01600
uniprot id: A0A3S5EP46
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS08560
gene id: 28135:EL210_RS08560
uniprot id: A0A448L702
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

28135:EL210 RS06720
gene id: 28135:EL210_RS06720
uniprot id: A0A3S4T5Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS11965
gene id: 28135:EL210_RS11965
uniprot id: A0A3S4X8U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

28135:EL210 RS11870
gene id: 28135:EL210_RS11870
uniprot id: A0A448L921
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

28135:EL210 RS10630
gene id: 28135:EL210_RS10630
uniprot id: A0A3S4VAU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

28135:EL210 RS08480
gene id: 28135:EL210_RS08480
uniprot id: A0A448L709
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS01490
gene id: 28135:EL210_RS01490
uniprot id: A0A448L2Y8
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

28135:EL210 RS11270
gene id: 28135:EL210_RS11270
uniprot id: A0A3S4TYR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

28135:EL210 RS02890
gene id: 28135:EL210_RS02890
uniprot id: A0A3S4T4G2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28135:EL210 RS05140
gene id: 28135:EL210_RS05140
uniprot id: A0A448L562
names: Similarity
messages: Belongs to the RecJ family.

28135:EL210 RS06645
gene id: 28135:EL210_RS06645
uniprot id: A0A3S4TBA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

28135:EL210 RS09245
gene id: 28135:EL210_RS09245
uniprot id: A0A448L7Q0
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

28135:EL210 RS11380
gene id: 28135:EL210_RS11380
uniprot id: A0A3S4T728
names: Similarity
messages: Belongs to the xylose isomerase family.

28135:EL210 RS04685
gene id: 28135:EL210_RS04685
uniprot id: A0A448L4T1
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS09635
gene id: 28135:EL210_RS09635
uniprot id: A0A3S4TC76
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

28135:EL210 RS06560
gene id: 28135:EL210_RS06560
uniprot id: A0A3S4X748
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS11275
gene id: 28135:EL210_RS11275
uniprot id: A0A448L8L6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

28135:EL210 RS04705
gene id: 28135:EL210_RS04705
uniprot id: A0A448L4T5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS12365
gene id: 28135:EL210_RS12365
uniprot id: A0A448L976
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

28135:EL210 RS01640
gene id: 28135:EL210_RS01640
uniprot id: A0A3S4T0Q1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS07520
gene id: 28135:EL210_RS07520
uniprot id: A0A448L6K2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

28135:EL210 RS02215
gene id: 28135:EL210_RS02215
uniprot id: A0A448L3E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS11950
gene id: 28135:EL210_RS11950
uniprot id: A0A448L8Z4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

28135:EL210 RS02490
gene id: 28135:EL210_RS02490
uniprot id: A0A3S4TW29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

28135:EL210 RS08685
gene id: 28135:EL210_RS08685
uniprot id: A0A448L703
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

28135:EL210 RS10770
gene id: 28135:EL210_RS10770
uniprot id: A0A448L888
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

28135:EL210 RS06815
gene id: 28135:EL210_RS06815
uniprot id: A0A3S4TEY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

28135:EL210 RS01180
gene id: 28135:EL210_RS01180
uniprot id: A0A3S4T0K8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

28135:EL210 RS05870
gene id: 28135:EL210_RS05870
uniprot id: A0A3S4V9F3
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS09150
gene id: 28135:EL210_RS09150
uniprot id: A0A3S4TC17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

28135:EL210 RS06250
gene id: 28135:EL210_RS06250
uniprot id: A0A3S4X704
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS12055
gene id: 28135:EL210_RS12055
uniprot id: A0A3S4T7C3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

28135:EL210 RS12715
gene id: 28135:EL210_RS12715
uniprot id: A0A448L9B4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS11080
gene id: 28135:EL210_RS11080
uniprot id: A0A448L8D8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

28135:EL210 RS05255
gene id: 28135:EL210_RS05255
uniprot id: A0A448L519
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

28135:EL210 RS02750
gene id: 28135:EL210_RS02750
uniprot id: A0A3S4TW53
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

28135:EL210 RS02235
gene id: 28135:EL210_RS02235
uniprot id: A0A3S4V8B0
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

28135:EL210 RS11240
gene id: 28135:EL210_RS11240
uniprot id: A0A448L8K8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

28135:EL210 RS06425
gene id: 28135:EL210_RS06425
uniprot id: A0A3S4X730
names: Similarity
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

28135:EL210 RS06310
gene id: 28135:EL210_RS06310
uniprot id: A0A3S4TEP8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

28135:EL210 RS11985
gene id: 28135:EL210_RS11985
uniprot id: A0A448L918
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

28135:EL210 RS06650
gene id: 28135:EL210_RS06650
uniprot id: A0A448L5V4
names: Similarity
messages: Belongs to the NusB family.

28135:EL210 RS11875
gene id: 28135:EL210_RS11875
uniprot id: A0A448L8Y8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

28135:EL210 RS08530
gene id: 28135:EL210_RS08530
uniprot id: A0A448L718
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

28135:EL210 RS03070
gene id: 28135:EL210_RS03070
uniprot id: A0A3S4T4I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

28135:EL210 RS03935
gene id: 28135:EL210_RS03935
uniprot id: A0A448L4E3
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

28135:EL210 RS01935
gene id: 28135:EL210_RS01935
uniprot id: A0A448L3B1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

28135:EL210 RS01325
gene id: 28135:EL210_RS01325
uniprot id: A0A448L2S0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

28135:EL210 RS06115
gene id: 28135:EL210_RS06115
uniprot id: A0A448L5J9
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS08025
gene id: 28135:EL210_RS08025
uniprot id: A0A448L6P0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

28135:EL210 RS10590
gene id: 28135:EL210_RS10590
uniprot id: A0A448L8E4
names: Similarity
messages: Belongs to the peptidase S8 family.

28135:EL210 RS00775
gene id: 28135:EL210_RS00775
uniprot id: A0A448L2F7
names: Similarity
messages: Belongs to the ParB family.

28135:EL210 RS08520
gene id: 28135:EL210_RS08520
uniprot id: A0A448L749
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS11925
gene id: 28135:EL210_RS11925
uniprot id: A0A3S4VB98
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

28135:EL210 RS07835
gene id: 28135:EL210_RS07835
uniprot id: A0A3S4UM50
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

28135:EL210 RS01485
gene id: 28135:EL210_RS01485
uniprot id: A0A448L307
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

28135:EL210 RS11245
gene id: 28135:EL210_RS11245
uniprot id: A0A3S4VB10
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

28135:EL210 RS00715
gene id: 28135:EL210_RS00715
uniprot id: A0A3S4X588
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

28135:EL210 RS13280
gene id: 28135:EL210_RS13280
uniprot id: A0A3S4UNP6
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

28135:EL210 RS05420
gene id: 28135:EL210_RS05420
uniprot id: A0A448L585
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

28135:EL210 RS13125
gene id: 28135:EL210_RS13125
uniprot id: A0A3S4TZB7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

28135:EL210 RS03470
gene id: 28135:EL210_RS03470
uniprot id: A0A3S4T4M1
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

28135:EL210 RS08840
gene id: 28135:EL210_RS08840
uniprot id: A0A3S4VAB3
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

28135:EL210 RS01425
gene id: 28135:EL210_RS01425
uniprot id: A0A448L2U4
names: Similarity
messages: Belongs to the glycosyltransferase 6 family.

28135:EL210 RS08415
gene id: 28135:EL210_RS08415
uniprot id: A0A3S4X7Q5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

28135:EL210 RS10975
gene id: 28135:EL210_RS10975
uniprot id: A0A448L8E7
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

28135:EL210 RS11500
gene id: 28135:EL210_RS11500
uniprot id: A0A3S4T3Q7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

28135:EL210 RS01115
gene id: 28135:EL210_RS01115
uniprot id: A0A448L2S2
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

28135:EL210 RS02935
gene id: 28135:EL210_RS02935
uniprot id: A0A448L3T5
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS12320
gene id: 28135:EL210_RS12320
uniprot id: A0A3S4T7E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

28135:EL210 RS01605
gene id: 28135:EL210_RS01605
uniprot id: A0A3S4T9G5
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

28135:EL210 RS01310
gene id: 28135:EL210_RS01310
uniprot id: A0A3S4T410
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

28135:EL210 RS11645
gene id: 28135:EL210_RS11645
uniprot id: A0A3S4TYW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

28135:EL210 RS07245
gene id: 28135:EL210_RS07245
uniprot id: A0A448L679
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

28135:EL210 RS08910
gene id: 28135:EL210_RS08910
uniprot id: A0A3S4UME7
names: Similarity
messages: Belongs to the cytochrome c-552 family.

28135:EL210 RS12720
gene id: 28135:EL210_RS12720
uniprot id: A0A448L9Q1
names: Subcellular Location Annotation
messages: Cytoplasm

28135:EL210 RS02415
gene id: 28135:EL210_RS02415
uniprot id: A0A3S4T9T7
names: Similarity
messages: Belongs to the DapB family.

28135:EL210 RS01515
gene id: 28135:EL210_RS01515
uniprot id: A0A3S5EP45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

28135:EL210 RS03455
gene id: 28135:EL210_RS03455
uniprot id: A0A448L419
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

28135:EL210 RS04205
gene id: 28135:EL210_RS04205
uniprot id: A0A448L4I3
names: Similarity
messages: Belongs to the SufE family.

28135:EL210 RS08460
gene id: 28135:EL210_RS08460
uniprot id: A0A448L6X2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

28135:EL210 RS06290
gene id: 28135:EL210_RS06290
uniprot id: A0A448L5N9
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS00450
gene id: 28135:EL210_RS00450
uniprot id: A0A3S4TVJ0
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

28135:EL210 RS05195
gene id: 28135:EL210_RS05195
uniprot id: A0A3S4X1I2
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

28135:EL210 RS03065
gene id: 28135:EL210_RS03065
uniprot id: A0A448L3W8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

28135:EL210 RS11230
gene id: 28135:EL210_RS11230
uniprot id: A0A448L8T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

28135:EL210 RS11235
gene id: 28135:EL210_RS11235
uniprot id: A0A3S4TG80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

28135:EL210 RS10905
gene id: 28135:EL210_RS10905
uniprot id: A0A3S4T3J1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

28135:EL210 RS06285
gene id: 28135:EL210_RS06285
uniprot id: A0A3S4T5J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

28135:EL210 RS10255
gene id: 28135:EL210_RS10255
uniprot id: A0A448L7Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS08715
gene id: 28135:EL210_RS08715
uniprot id: A0A448L758
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

28135:EL210 RS12705
gene id: 28135:EL210_RS12705
uniprot id: A0A448L9C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

28135:EL210 RS13080
gene id: 28135:EL210_RS13080
uniprot id: A0A3S5EPH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

28135:EL210 RS09280
gene id: 28135:EL210_RS09280
uniprot id: A0A3S4X7Z2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

28135:EL210 RS07040
gene id: 28135:EL210_RS07040
uniprot id: A0A3S4TXE5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

28135:EL210 RS07260
gene id: 28135:EL210_RS07260
uniprot id: A0A3S4TF23
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS12825
gene id: 28135:EL210_RS12825
uniprot id: A0A448L9D9
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

28135:EL210 RS00800
gene id: 28135:EL210_RS00800
uniprot id: A0A448L2J4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

28135:EL210 RS07970
gene id: 28135:EL210_RS07970
uniprot id: A0A3S4TXN8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

28135:EL210 RS04390
gene id: 28135:EL210_RS04390
uniprot id: A0A448L4N0
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

28135:EL210 RS11935
gene id: 28135:EL210_RS11935
uniprot id: A0A448L8X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

28135:EL210 RS03420
gene id: 28135:EL210_RS03420
uniprot id: A0A3S4TWB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

28135:EL210 RS06420
gene id: 28135:EL210_RS06420
uniprot id: A0A448L5Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

28135:EL210 RS01280
gene id: 28135:EL210_RS01280
uniprot id: A0A448L2R3
names: Similarity
messages: Belongs to the peptidase S13 family.

28135:EL210 RS01685
gene id: 28135:EL210_RS01685
uniprot id: A0A3S4TD72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

28135:EL210 RS03540
gene id: 28135:EL210_RS03540
uniprot id: A0A448L455
names: Similarity
messages: Belongs to the peptidase M16 family.

28135:EL210 RS07335
gene id: 28135:EL210_RS07335
uniprot id: A0A3S4X7D5
names: Similarity
messages: Belongs to the peptidase M13 family.

28135:EL210 RS00420
gene id: 28135:EL210_RS00420
uniprot id: A0A3S4X049
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

28135:EL210 RS02495
gene id: 28135:EL210_RS02495
uniprot id: A0A3S4X5Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

28135:EL210 RS02785
gene id: 28135:EL210_RS02785
uniprot id: A0A3S4T9Y0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

28135:EL210 RS09045
gene id: 28135:EL210_RS09045
uniprot id: A0A448L7A5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

28135:EL210 RS03860
gene id: 28135:EL210_RS03860
uniprot id: A0A3S5EP70
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

28135:EL210 RS04760
gene id: 28135:EL210_RS04760
uniprot id: A0A448L4S8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

28135:EL210 RS12650
gene id: 28135:EL210_RS12650
uniprot id: A0A448L998
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

28135:EL210 RS08885
gene id: 28135:EL210_RS08885
uniprot id: A0A3S4TBY4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

28135:EL210 RS08555
gene id: 28135:EL210_RS08555
uniprot id: A0A3S4X2M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

28135:EL210 RS11900
gene id: 28135:EL210_RS11900
uniprot id: A0A448L8Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

28135:EL210 RS05075
gene id: 28135:EL210_RS05075
uniprot id: A0A448L505
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

28135:EL210 RS03730
gene id: 28135:EL210_RS03730
uniprot id: A0A3S4UKX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS07540
gene id: 28135:EL210_RS07540
uniprot id: A0A448L6D6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

28135:EL210 RS09880
gene id: 28135:EL210_RS09880
uniprot id: A0A448L7R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS08305
gene id: 28135:EL210_RS08305
uniprot id: A0A3S4VA75
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

28135:EL210 RS02850
gene id: 28135:EL210_RS02850
uniprot id: A0A3S4X5V4
names: Similarity
messages: Belongs to the UPF0246 family.

28135:EL210 RS01635
gene id: 28135:EL210_RS01635
uniprot id: A0A3S4V851
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

28135:EL210 RS02755
gene id: 28135:EL210_RS02755
uniprot id: A0A3S4X5U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

28135:EL210 RS09195
gene id: 28135:EL210_RS09195
uniprot id: A0A3S4TFM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

28135:EL210 RS05315
gene id: 28135:EL210_RS05315
uniprot id: A0A3S4T1Q3
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS00230
gene id: 28135:EL210_RS00230
uniprot id: A0A448L2A2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28135:EL210 RS02950
gene id: 28135:EL210_RS02950
uniprot id: A0A3S5EP60
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS13090
gene id: 28135:EL210_RS13090
uniprot id: A0A3S4T7N7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

28135:EL210 RS10910
gene id: 28135:EL210_RS10910
uniprot id: A0A448L8B9
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS10585
gene id: 28135:EL210_RS10585
uniprot id: A0A3S4X363
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

28135:EL210 RS04435
gene id: 28135:EL210_RS04435
uniprot id: A0A448L4P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

28135:EL210 RS09160
gene id: 28135:EL210_RS09160
uniprot id: A0A448L7M4
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

28135:EL210 RS08600
gene id: 28135:EL210_RS08600
uniprot id: A0A448L773
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

28135:EL210 RS03855
gene id: 28135:EL210_RS03855
uniprot id: A0A448L4B7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

28135:EL210 RS03095
gene id: 28135:EL210_RS03095
uniprot id: A0A3S4UKR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

28135:EL210 RS11845
gene id: 28135:EL210_RS11845
uniprot id: A0A3S4T3V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

28135:EL210 RS10550
gene id: 28135:EL210_RS10550
uniprot id: A0A448L834
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

28135:EL210 RS08590
gene id: 28135:EL210_RS08590
uniprot id: A0A448L713
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

28135:EL210 RS07385
gene id: 28135:EL210_RS07385
uniprot id: A0A3S4T2C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

28135:EL210 RS08835
gene id: 28135:EL210_RS08835
uniprot id: A0A3S4TFI7
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

28135:EL210 RS09875
gene id: 28135:EL210_RS09875
uniprot id: A0A3S4TCA5
names: Similarity
messages: Belongs to the SusD family.

28135:EL210 RS08160
gene id: 28135:EL210_RS08160
uniprot id: A0A3S4TBS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

28135:EL210 RS03775
gene id: 28135:EL210_RS03775
uniprot id: A0A3S5EP69
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS09030
gene id: 28135:EL210_RS09030
uniprot id: A0A448L7C0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS06295
gene id: 28135:EL210_RS06295
uniprot id: A0A3S4X1W7
names: Similarity
messages: Belongs to the serpin family.

28135:EL210 RS06440
gene id: 28135:EL210_RS06440
uniprot id: A0A448L5S7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28135:EL210 RS07510
gene id: 28135:EL210_RS07510
uniprot id: A0A3S4TBK8
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS04860
gene id: 28135:EL210_RS04860
uniprot id: A0A3S4T1L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS08945
gene id: 28135:EL210_RS08945
uniprot id: A0A3S4T2W1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS09825
gene id: 28135:EL210_RS09825
uniprot id: A0A448L7R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

28135:EL210 RS12700
gene id: 28135:EL210_RS12700
uniprot id: A0A3S4T7J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

28135:EL210 RS03905
gene id: 28135:EL210_RS03905
uniprot id: A0A3S4T1C1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

28135:EL210 RS12030
gene id: 28135:EL210_RS12030
uniprot id: A0A3S4T3X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

28135:EL210 RS01440
gene id: 28135:EL210_RS01440
uniprot id: A0A3S4X0F0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

28135:EL210 RS11960
gene id: 28135:EL210_RS11960
uniprot id: A0A448L8X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

28135:EL210 RS04120
gene id: 28135:EL210_RS04120
uniprot id: A0A448L4G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

28135:EL210 RS08580
gene id: 28135:EL210_RS08580
uniprot id: A0A448L6Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

28135:EL210 RS01155
gene id: 28135:EL210_RS01155
uniprot id: A0A448L2V7
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS12285
gene id: 28135:EL210_RS12285
uniprot id: A0A3S4X8X5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

28135:EL210 RS11070
gene id: 28135:EL210_RS11070
uniprot id: A0A3S4X3A5
names: Similarity
messages: Belongs to the thioredoxin family.

28135:EL210 RS00760
gene id: 28135:EL210_RS00760
uniprot id: A0A448L2L4
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

28135:EL210 RS07920
gene id: 28135:EL210_RS07920
uniprot id: A0A448L6T6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

28135:EL210 RS06565
gene id: 28135:EL210_RS06565
uniprot id: A0A3S5EP99
names: Similarity
messages: Belongs to the UxaA family.

28135:EL210 RS08165
gene id: 28135:EL210_RS08165
uniprot id: A0A448L6Y6
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS10805
gene id: 28135:EL210_RS10805
uniprot id: A0A3S4UMZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

28135:EL210 RS04135
gene id: 28135:EL210_RS04135
uniprot id: A0A3S4X177
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS07025
gene id: 28135:EL210_RS07025
uniprot id: A0A3S4V9T6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

28135:EL210 RS11225
gene id: 28135:EL210_RS11225
uniprot id: A0A3S4UN44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

28135:EL210 RS12160
gene id: 28135:EL210_RS12160
uniprot id: A0A3S4TD11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

28135:EL210 RS08985
gene id: 28135:EL210_RS08985
uniprot id: A0A448L793
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

28135:EL210 RS12530
gene id: 28135:EL210_RS12530
uniprot id: A0A3S4X8Z6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

28135:EL210 RS13220
gene id: 28135:EL210_RS13220
uniprot id: A0A448LA10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

28135:EL210 RS02955
gene id: 28135:EL210_RS02955
uniprot id: A0A3S4T9Z7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

28135:EL210 RS02660
gene id: 28135:EL210_RS02660
uniprot id: A0A3S4TW46
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS06760
gene id: 28135:EL210_RS06760
uniprot id: A0A448L5Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

28135:EL210 RS02645
gene id: 28135:EL210_RS02645
uniprot id: A0A448L3M4
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS01740
gene id: 28135:EL210_RS01740
uniprot id: A0A3S4T454
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

28135:EL210 RS04300
gene id: 28135:EL210_RS04300
uniprot id: A0A3S4TAE5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

28135:EL210 RS11065
gene id: 28135:EL210_RS11065
uniprot id: A0A3S4TCM5
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS01000
gene id: 28135:EL210_RS01000
uniprot id: A0A448L2R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS02725
gene id: 28135:EL210_RS02725
uniprot id: A0A448L3N4
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

28135:EL210 RS01165
gene id: 28135:EL210_RS01165
uniprot id: A0A3S4V804
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

28135:EL210 RS11005
gene id: 28135:EL210_RS11005
uniprot id: A0A3S4T6Y9
names: Similarity
messages: Belongs to the UPF0102 family.

28135:EL210 RS09585
gene id: 28135:EL210_RS09585
uniprot id: A0A3S4TY75
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

28135:EL210 RS12255
gene id: 28135:EL210_RS12255
uniprot id: A0A3S4T3Z1
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS00915
gene id: 28135:EL210_RS00915
uniprot id: A0A3S5EP39
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

28135:EL210 RS05470
gene id: 28135:EL210_RS05470
uniprot id: A0A448L596
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

28135:EL210 RS01730
gene id: 28135:EL210_RS01730
uniprot id: A0A448L352
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

28135:EL210 RS02465
gene id: 28135:EL210_RS02465
uniprot id: A0A448L3H8
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

28135:EL210 RS03800
gene id: 28135:EL210_RS03800
uniprot id: A0A448L487
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS06260
gene id: 28135:EL210_RS06260
uniprot id: A0A448L5N0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS12730
gene id: 28135:EL210_RS12730
uniprot id: A0A3S4UNI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

28135:EL210 RS08400
gene id: 28135:EL210_RS08400
uniprot id: A0A448L6U0
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

28135:EL210 RS12835
gene id: 28135:EL210_RS12835
uniprot id: A0A3S4TGS5
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

28135:EL210 RS07905
gene id: 28135:EL210_RS07905
uniprot id: A0A448L6I9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

28135:EL210 RS04075
gene id: 28135:EL210_RS04075
uniprot id: A0A3S4TWH9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

28135:EL210 RS12300
gene id: 28135:EL210_RS12300
uniprot id: A0A448L955
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

28135:EL210 RS09300
gene id: 28135:EL210_RS09300
uniprot id: A0A3S4TC37
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

28135:EL210 RS04865
gene id: 28135:EL210_RS04865
uniprot id: A0A448L4W1
names: Similarity
messages: Belongs to the SusD family.

28135:EL210 RS05125
gene id: 28135:EL210_RS05125
uniprot id: A0A3S4TWT0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS11980
gene id: 28135:EL210_RS11980
uniprot id: A0A3S4TCZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

28135:EL210 RS09785
gene id: 28135:EL210_RS09785
uniprot id: A0A3S4X850
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

28135:EL210 RS08325
gene id: 28135:EL210_RS08325
uniprot id: A0A3S4TXT0
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

28135:EL210 RS02270
gene id: 28135:EL210_RS02270
uniprot id: A0A448L3F9
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

28135:EL210 RS09420
gene id: 28135:EL210_RS09420
uniprot id: A0A448L7H0
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

28135:EL210 RS09220
gene id: 28135:EL210_RS09220
uniprot id: A0A3S5EPC9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

28135:EL210 RS07515
gene id: 28135:EL210_RS07515
uniprot id: A0A448L6E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

28135:EL210 RS07865
gene id: 28135:EL210_RS07865
uniprot id: A0A3S4TXN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

28135:EL210 RS08860
gene id: 28135:EL210_RS08860
uniprot id: A0A448L756
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

28135:EL210 RS01190
gene id: 28135:EL210_RS01190
uniprot id: A0A3S4X5D0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

28135:EL210 RS06535
gene id: 28135:EL210_RS06535
uniprot id: A0A3S4ULR4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS11585
gene id: 28135:EL210_RS11585
uniprot id: A0A3S4TYV8
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

28135:EL210 RS02435
gene id: 28135:EL210_RS02435
uniprot id: A0A3S4X0P5
names: Similarity
messages: Belongs to the DEAD box helicase family.

28135:EL210 RS11135
gene id: 28135:EL210_RS11135
uniprot id: A0A448L8E8
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS05155
gene id: 28135:EL210_RS05155
uniprot id: A0A3S4X6L4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

28135:EL210 RS04225
gene id: 28135:EL210_RS04225
uniprot id: A0A448L4J7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

28135:EL210 RS11440
gene id: 28135:EL210_RS11440
uniprot id: A0A3S4X3E4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm

28135:EL210 RS03100
gene id: 28135:EL210_RS03100
uniprot id: A0A448L3W4
names: Similarity
messages: Belongs to the peptidase S13 family.

28135:EL210 RS05110
gene id: 28135:EL210_RS05110
uniprot id: A0A448L4Z8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS11085
gene id: 28135:EL210_RS11085
uniprot id: A0A3S4TG63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

28135:EL210 RS00445
gene id: 28135:EL210_RS00445
uniprot id: A0A3S4T0C8
names: Similarity
messages: Belongs to the DapA family.

28135:EL210 RS13290
gene id: 28135:EL210_RS13290
uniprot id: A0A448L9P3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

28135:EL210 RS02350
gene id: 28135:EL210_RS02350
uniprot id: A0A448L3G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS01505
gene id: 28135:EL210_RS01505
uniprot id: A0A448L329
names: Cofactor
messages: Binds 1 zinc ion per subunit.

28135:EL210 RS12135
gene id: 28135:EL210_RS12135
uniprot id: A0A3S4X8W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

28135:EL210 RS09760
gene id: 28135:EL210_RS09760
uniprot id: A0A3S4TFU4
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

28135:EL210 RS09385
gene id: 28135:EL210_RS09385
uniprot id: A0A448L7P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

28135:EL210 RS11945
gene id: 28135:EL210_RS11945
uniprot id: A0A3S4T3W5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

28135:EL210 RS00215
gene id: 28135:EL210_RS00215
uniprot id: A0A3S4T3P3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

28135:EL210 RS01320
gene id: 28135:EL210_RS01320
uniprot id: A0A3S4X0E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

28135:EL210 RS12635
gene id: 28135:EL210_RS12635
uniprot id: A0A3S4VBH0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

28135:EL210 RS07760
gene id: 28135:EL210_RS07760
uniprot id: A0A3S4TXM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

28135:EL210 RS10700
gene id: 28135:EL210_RS10700
uniprot id: A0A448L884
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

28135:EL210 RS01765
gene id: 28135:EL210_RS01765
uniprot id: A0A3S4TD84
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

28135:EL210 RS00880
gene id: 28135:EL210_RS00880
uniprot id: A0A3S4V7X3
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

28135:EL210 RS06885
gene id: 28135:EL210_RS06885
uniprot id: A0A448L659
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

28135:EL210 RS06980
gene id: 28135:EL210_RS06980
uniprot id: A0A448L635
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS01510
gene id: 28135:EL210_RS01510
uniprot id: A0A448L300
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28135:EL210 RS12180
gene id: 28135:EL210_RS12180
uniprot id: A0A3S4UNE6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

28135:EL210 RS00305
gene id: 28135:EL210_RS00305
uniprot id: A0A3S5EP32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

28135:EL210 RS03000
gene id: 28135:EL210_RS03000
uniprot id: A0A448L3V5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

28135:EL210 RS02310
gene id: 28135:EL210_RS02310
uniprot id: A0A3S4T9S4
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

28135:EL210 RS03995
gene id: 28135:EL210_RS03995
uniprot id: A0A448L4F5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

28135:EL210 RS00710
gene id: 28135:EL210_RS00710
uniprot id: A0A448L2L8
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

28135:EL210 RS09845
gene id: 28135:EL210_RS09845
uniprot id: A0A3S4T377
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

28135:EL210 RS11940
gene id: 28135:EL210_RS11940
uniprot id: A0A448L909
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

28135:EL210 RS13060
gene id: 28135:EL210_RS13060
uniprot id: A0A3S4T484
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

28135:EL210 RS06920
gene id: 28135:EL210_RS06920
uniprot id: A0A448L620
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

28135:EL210 RS12555
gene id: 28135:EL210_RS12555
uniprot id: A0A3S4UNH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

28135:EL210 RS12620
gene id: 28135:EL210_RS12620
uniprot id: A0A3S4X3S0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

28135:EL210 RS04440
gene id: 28135:EL210_RS04440
uniprot id: A0A3S4X1B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

28135:EL210 RS08040
gene id: 28135:EL210_RS08040
uniprot id: A0A448L6M8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

28135:EL210 RS12680
gene id: 28135:EL210_RS12680
uniprot id: A0A3S5EPG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

28135:EL210 RS07740
gene id: 28135:EL210_RS07740
uniprot id: A0A3S4VA12
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

28135:EL210 RS11285
gene id: 28135:EL210_RS11285
uniprot id: A0A448L8U6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

28135:EL210 RS07895
gene id: 28135:EL210_RS07895
uniprot id: A0A448L6K6
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

28135:EL210 RS07430
gene id: 28135:EL210_RS07430
uniprot id: A0A3S4TBJ9
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

28135:EL210 RS06465
gene id: 28135:EL210_RS06465
uniprot id: A0A448L5R6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

28135:EL210 RS05660
gene id: 28135:EL210_RS05660
uniprot id: A0A3S4T1T7
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS07330
gene id: 28135:EL210_RS07330
uniprot id: A0A3S4TXI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

28135:EL210 RS09515
gene id: 28135:EL210_RS09515
uniprot id: A0A448L7G8
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

28135:EL210 RS12525
gene id: 28135:EL210_RS12525
uniprot id: A0A448L9L0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

28135:EL210 RS03910
gene id: 28135:EL210_RS03910
uniprot id: A0A448L4C8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS12710
gene id: 28135:EL210_RS12710
uniprot id: A0A448L9E1
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS02395
gene id: 28135:EL210_RS02395
uniprot id: A0A3S4X5P5
names: Similarity
messages: Belongs to the DprA/Smf family.

28135:EL210 RS11280
gene id: 28135:EL210_RS11280
uniprot id: A0A3S4X8K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

28135:EL210 RS07480
gene id: 28135:EL210_RS07480
uniprot id: A0A3S4T2E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

28135:EL210 RS11855
gene id: 28135:EL210_RS11855
uniprot id: A0A3S4TYZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

28135:EL210 RS06245
gene id: 28135:EL210_RS06245
uniprot id: A0A3S4TX36
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS01120
gene id: 28135:EL210_RS01120
uniprot id: A0A3S5EP41
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

28135:EL210 RS11515
gene id: 28135:EL210_RS11515
uniprot id: A0A3S4X8N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

28135:EL210 RS02790
gene id: 28135:EL210_RS02790
uniprot id: A0A448L3Q6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

28135:EL210 RS05875
gene id: 28135:EL210_RS05875
uniprot id: A0A3S4T1V8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

28135:EL210 RS03815
gene id: 28135:EL210_RS03815
uniprot id: A0A3S4TDU1
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

28135:EL210 RS02525
gene id: 28135:EL210_RS02525
uniprot id: A0A3S4T4B6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

28135:EL210 RS11710
gene id: 28135:EL210_RS11710
uniprot id: A0A448L8V0
names: Similarity
messages: Belongs to the SusD family.

28135:EL210 RS09305
gene id: 28135:EL210_RS09305
uniprot id: A0A3S4T6J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS03190
gene id: 28135:EL210_RS03190
uniprot id: A0A3S4TDL5
names: Similarity
messages: Belongs to the peptidase S9A family.

28135:EL210 RS10715
gene id: 28135:EL210_RS10715
uniprot id: A0A448L851
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

28135:EL210 RS04455
gene id: 28135:EL210_RS04455
uniprot id: A0A3S4TE23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

28135:EL210 RS06180
gene id: 28135:EL210_RS06180
uniprot id: A0A448L5S2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

28135:EL210 RS02150
gene id: 28135:EL210_RS02150
uniprot id: A0A3S4X5M6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

28135:EL210 RS04690
gene id: 28135:EL210_RS04690
uniprot id: A0A3S4X6H3
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS09345
gene id: 28135:EL210_RS09345
uniprot id: A0A448L7H7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

28135:EL210 RS09275
gene id: 28135:EL210_RS09275
uniprot id: A0A3S4TY27
names: Caution
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS10915
gene id: 28135:EL210_RS10915
uniprot id: A0A448L8L0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

28135:EL210 RS11890
gene id: 28135:EL210_RS11890
uniprot id: A0A3S4X3K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

28135:EL210 RS07285
gene id: 28135:EL210_RS07285
uniprot id: A0A3S4X7C7
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

28135:EL210 RS04590
gene id: 28135:EL210_RS04590
uniprot id: A0A448L4S1
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS09205
gene id: 28135:EL210_RS09205
uniprot id: A0A448L7N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

28135:EL210 RS08050
gene id: 28135:EL210_RS08050
uniprot id: A0A3S4TXP9
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

28135:EL210 RS07255
gene id: 28135:EL210_RS07255
uniprot id: A0A448L6B4
names: Function
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Belongs to the cellobiose 2-epimerase family.
messages: Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).

28135:EL210 RS09020
gene id: 28135:EL210_RS09020
uniprot id: A0A3S4T2X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

28135:EL210 RS04530
gene id: 28135:EL210_RS04530
uniprot id: A0A3S4TAG3
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

28135:EL210 RS04920
gene id: 28135:EL210_RS04920
uniprot id: A0A448L4Z5
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

28135:EL210 RS02625
gene id: 28135:EL210_RS02625
uniprot id: A0A448L3N2
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS10860
gene id: 28135:EL210_RS10860
uniprot id: A0A448L8B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

28135:EL210 RS06935
gene id: 28135:EL210_RS06935
uniprot id: A0A3S4T5T9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

28135:EL210 RS01330
gene id: 28135:EL210_RS01330
uniprot id: A0A448L2S3
names: Similarity
messages: Belongs to the glutathione peroxidase family.

28135:EL210 RS02280
gene id: 28135:EL210_RS02280
uniprot id: A0A3S4TW10
names: Similarity
messages: Belongs to the SusD family.

28135:EL210 RS02530
gene id: 28135:EL210_RS02530
uniprot id: A0A448L3L1
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

28135:EL210 RS04400
gene id: 28135:EL210_RS04400
uniprot id: A0A3S5EP76
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

28135:EL210 RS03940
gene id: 28135:EL210_RS03940
uniprot id: A0A3S5EP71
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

28135:EL210 RS09400
gene id: 28135:EL210_RS09400
uniprot id: A0A448L7G3
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

28135:EL210 RS12820
gene id: 28135:EL210_RS12820
uniprot id: A0A3S4X3U3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

28135:EL210 RS12155
gene id: 28135:EL210_RS12155
uniprot id: A0A448L950
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

28135:EL210 RS06415
gene id: 28135:EL210_RS06415
uniprot id: A0A3S4TX61
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS03365
gene id: 28135:EL210_RS03365
uniprot id: A0A3S4T4L0
names: Similarity
messages: Belongs to the CvfB family.

28135:EL210 RS02745
gene id: 28135:EL210_RS02745
uniprot id: A0A448L3P5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

28135:EL210 RS06635
gene id: 28135:EL210_RS06635
uniprot id: A0A448L5V2
names: Similarity
messages: Belongs to the HSP15 family.

28135:EL210 RS07820
gene id: 28135:EL210_RS07820
uniprot id: A0A3S4X2G1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

28135:EL210 RS09140
gene id: 28135:EL210_RS09140
uniprot id: A0A3S4X7X1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

28135:EL210 RS05160
gene id: 28135:EL210_RS05160
uniprot id: A0A448L509
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

28135:EL210 RS09410
gene id: 28135:EL210_RS09410
uniprot id: A0A3S4VAH4
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

28135:EL210 RS07815
gene id: 28135:EL210_RS07815
uniprot id: A0A448L6R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

28135:EL210 RS05780
gene id: 28135:EL210_RS05780
uniprot id: A0A448L5C5
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

28135:EL210 RS06210
gene id: 28135:EL210_RS06210
uniprot id: A0A448L5L6
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

28135:EL210 RS08880
gene id: 28135:EL210_RS08880
uniprot id: A0A3S5EPC5
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

28135:EL210 RS11810
gene id: 28135:EL210_RS11810
uniprot id: A0A3S4X3J5
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

28135:EL210 RS02985
gene id: 28135:EL210_RS02985
uniprot id: A0A3S4TDJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

28135:EL210 RS08465
gene id: 28135:EL210_RS08465
uniprot id: A0A448L739
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

28135:EL210 RS01235
gene id: 28135:EL210_RS01235
uniprot id: A0A448L2T4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

28135:EL210 RS01775
gene id: 28135:EL210_RS01775
uniprot id: A0A448L326
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

28135:EL210 RS11955
gene id: 28135:EL210_RS11955
uniprot id: A0A3S4TZ07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

28135:EL210 RS02945
gene id: 28135:EL210_RS02945
uniprot id: A0A448L3U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS12580
gene id: 28135:EL210_RS12580
uniprot id: A0A3S4T416
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS06450
gene id: 28135:EL210_RS06450
uniprot id: A0A3S4T5L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

28135:EL210 RS08545
gene id: 28135:EL210_RS08545
uniprot id: A0A448L722
names: Similarity
messages: Belongs to the fabD family.

28135:EL210 RS09805
gene id: 28135:EL210_RS09805
uniprot id: A0A3S4T6Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

28135:EL210 RS02255
gene id: 28135:EL210_RS02255
uniprot id: A0A448L3F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

28135:EL210 RS07630
gene id: 28135:EL210_RS07630
uniprot id: A0A448L6F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

28135:EL210 RS06225
gene id: 28135:EL210_RS06225
uniprot id: A0A3S4V9I9
names: Similarity
messages: Belongs to the CobT family.

28135:EL210 RS01175
gene id: 28135:EL210_RS01175
uniprot id: A0A448L2T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

28135:EL210 RS11765
gene id: 28135:EL210_RS11765
uniprot id: A0A448L8U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

28135:EL210 RS07860
gene id: 28135:EL210_RS07860
uniprot id: A0A3S4T2H1
names: Similarity
messages: Belongs to the aldose epimerase family.

28135:EL210 RS08850
gene id: 28135:EL210_RS08850
uniprot id: A0A448L7F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

28135:EL210 RS02675
gene id: 28135:EL210_RS02675
uniprot id: A0A448L3M7
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS04045
gene id: 28135:EL210_RS04045
uniprot id: A0A3S4TDX4
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

28135:EL210 RS02420
gene id: 28135:EL210_RS02420
uniprot id: A0A448L3H2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28135:EL210 RS02060
gene id: 28135:EL210_RS02060
uniprot id: A0A448L379
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

28135:EL210 RS11675
gene id: 28135:EL210_RS11675
uniprot id: A0A448L8T8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

28135:EL210 RS05000
gene id: 28135:EL210_RS05000
uniprot id: A0A3S4T554
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

28135:EL210 RS09350
gene id: 28135:EL210_RS09350
uniprot id: A0A3S4T318
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28135:EL210 RS10965
gene id: 28135:EL210_RS10965
uniprot id: A0A448L8E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

28135:EL210 RS05365
gene id: 28135:EL210_RS05365
uniprot id: A0A448L555
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS12445
gene id: 28135:EL210_RS12445
uniprot id: A0A3S4UNG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

28135:EL210 RS01735
gene id: 28135:EL210_RS01735
uniprot id: A0A448L365
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

28135:EL210 RS01215
gene id: 28135:EL210_RS01215
uniprot id: A0A3S4UK90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

28135:EL210 RS03790
gene id: 28135:EL210_RS03790
uniprot id: A0A3S4T4R8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

28135:EL210 RS03015
gene id: 28135:EL210_RS03015
uniprot id: A0A3S4TW81
names: Similarity
messages: Belongs to the UPF0597 family.

28135:EL210 RS11910
gene id: 28135:EL210_RS11910
uniprot id: A0A448L8W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

28135:EL210 RS12035
gene id: 28135:EL210_RS12035
uniprot id: A0A3S4TZ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS09080
gene id: 28135:EL210_RS09080
uniprot id: A0A3S4TC06
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

28135:EL210 RS09200
gene id: 28135:EL210_RS09200
uniprot id: A0A3S4VAF0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

28135:EL210 RS10010
gene id: 28135:EL210_RS10010
uniprot id: A0A448L7U7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

28135:EL210 RS02635
gene id: 28135:EL210_RS02635
uniprot id: A0A3S4UKM1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

28135:EL210 RS09580
gene id: 28135:EL210_RS09580
uniprot id: A0A3S4T344
names: Similarity
messages: Belongs to the SusD family.

28135:EL210 RS04790
gene id: 28135:EL210_RS04790
uniprot id: A0A3S4TWP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS10760
gene id: 28135:EL210_RS10760
uniprot id: A0A448L891
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

28135:EL210 RS06665
gene id: 28135:EL210_RS06665
uniprot id: A0A3S4X221
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

28135:EL210 RS01675
gene id: 28135:EL210_RS01675
uniprot id: A0A3S4X0H6
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

28135:EL210 RS00440
gene id: 28135:EL210_RS00440
uniprot id: A0A448L2E5
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS06220
gene id: 28135:EL210_RS06220
uniprot id: A0A3S4TEN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

28135:EL210 RS11975
gene id: 28135:EL210_RS11975
uniprot id: A0A448L901
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

28135:EL210 RS00895
gene id: 28135:EL210_RS00895
uniprot id: A0A3S4X5A0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS00300
gene id: 28135:EL210_RS00300
uniprot id: A0A3S4X531
names: Similarity
messages: Belongs to the peptidase C10 family.

28135:EL210 RS09565
gene id: 28135:EL210_RS09565
uniprot id: A0A3S4TFS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm

28135:EL210 RS06740
gene id: 28135:EL210_RS06740
uniprot id: A0A448L5Y0
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

28135:EL210 RS02220
gene id: 28135:EL210_RS02220
uniprot id: A0A448L3C5
names: Similarity
messages: Belongs to the SusD family.

28135:EL210 RS02505
gene id: 28135:EL210_RS02505
uniprot id: A0A3S5EP55
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

28135:EL210 RS01130
gene id: 28135:EL210_RS01130
uniprot id: A0A3S4T3Z0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

28135:EL210 RS03610
gene id: 28135:EL210_RS03610
uniprot id: A0A448L467
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

28135:EL210 RS00885
gene id: 28135:EL210_RS00885
uniprot id: A0A3S4T0H7
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

28135:EL210 RS12520
gene id: 28135:EL210_RS12520
uniprot id: A0A3S4TZ52
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

28135:EL210 RS02775
gene id: 28135:EL210_RS02775
uniprot id: A0A448L3P9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

28135:EL210 RS02070
gene id: 28135:EL210_RS02070
uniprot id: A0A448L361
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

28135:EL210 RS03105
gene id: 28135:EL210_RS03105
uniprot id: A0A448L3W2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

28135:EL210 RS09960
gene id: 28135:EL210_RS09960
uniprot id: A0A3S4X317
names: Similarity
messages: Belongs to the GARS family.

28135:EL210 RS10680
gene id: 28135:EL210_RS10680
uniprot id: A0A3S4T6X5
names: Similarity
messages: Belongs to the type IA topoisomerase family.

28135:EL210 RS08140
gene id: 28135:EL210_RS08140
uniprot id: A0A448L6U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

28135:EL210 RS04540
gene id: 28135:EL210_RS04540
uniprot id: A0A448L4P6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS04425
gene id: 28135:EL210_RS04425
uniprot id: A0A448L4N6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

28135:EL210 RS04670
gene id: 28135:EL210_RS04670
uniprot id: A0A448L4S5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

28135:EL210 RS03845
gene id: 28135:EL210_RS03845
uniprot id: A0A448L488
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS10150
gene id: 28135:EL210_RS10150
uniprot id: A0A3S4TFY1
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS02680
gene id: 28135:EL210_RS02680
uniprot id: A0A3S5EP57
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28135:EL210 RS12050
gene id: 28135:EL210_RS12050
uniprot id: A0A3S4TD00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

28135:EL210 RS08440
gene id: 28135:EL210_RS08440
uniprot id: A0A3S4X2M0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

28135:EL210 RS04325
gene id: 28135:EL210_RS04325
uniprot id: A0A3S4X1A0
names: Similarity
messages: Belongs to the peptidase C40 family.

28135:EL210 RS12165
gene id: 28135:EL210_RS12165
uniprot id: A0A3S4T7D4
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

28135:EL210 RS04990
gene id: 28135:EL210_RS04990
uniprot id: A0A3S4TAL7
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS04545
gene id: 28135:EL210_RS04545
uniprot id: A0A3S4X1C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

28135:EL210 RS11665
gene id: 28135:EL210_RS11665
uniprot id: A0A3S4T770
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

28135:EL210 RS08320
gene id: 28135:EL210_RS08320
uniprot id: A0A3S4T2L5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

28135:EL210 RS05880
gene id: 28135:EL210_RS05880
uniprot id: A0A448L5L8
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

28135:EL210 RS11970
gene id: 28135:EL210_RS11970
uniprot id: A0A448L940
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

28135:EL210 RS09365
gene id: 28135:EL210_RS09365
uniprot id: A0A3S4X804
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

28135:EL210 RS11220
gene id: 28135:EL210_RS11220
uniprot id: A0A448L8K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

28135:EL210 RS07045
gene id: 28135:EL210_RS07045
uniprot id: A0A448L649
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

28135:EL210 RS08150
gene id: 28135:EL210_RS08150
uniprot id: A0A448L6P6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

28135:EL210 RS04420
gene id: 28135:EL210_RS04420
uniprot id: A0A448L4M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

28135:EL210 RS06270
gene id: 28135:EL210_RS06270
uniprot id: A0A3S4TB45
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

28135:EL210 RS07945
gene id: 28135:EL210_RS07945
uniprot id: A0A3S4VA35
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

28135:EL210 RS04980
gene id: 28135:EL210_RS04980
uniprot id: A0A448L4Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

28135:EL210 RS12815
gene id: 28135:EL210_RS12815
uniprot id: A0A448L9D1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

28135:EL210 RS03460
gene id: 28135:EL210_RS03460
uniprot id: A0A3S4TA49
names: Similarity
messages: Belongs to the asparaginase 1 family.

28135:EL210 RS11770
gene id: 28135:EL210_RS11770
uniprot id: A0A3S4X3I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

28135:EL210 RS04130
gene id: 28135:EL210_RS04130
uniprot id: A0A448L4H9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

28135:EL210 RS07625
gene id: 28135:EL210_RS07625
uniprot id: A0A448L6F2
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS02905
gene id: 28135:EL210_RS02905
uniprot id: A0A3S4TDI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

28135:EL210 RS04785
gene id: 28135:EL210_RS04785
uniprot id: A0A448L4W0
names: Similarity
messages: Belongs to the SusD family.

28135:EL210 RS07465
gene id: 28135:EL210_RS07465
uniprot id: A0A3S4V9Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

28135:EL210 RS01135
gene id: 28135:EL210_RS01135
uniprot id: A0A448L2U3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

28135:EL210 RS09070
gene id: 28135:EL210_RS09070
uniprot id: A0A448L7C6
names: Similarity
messages: Belongs to the IMPACT family.

28135:EL210 RS02650
gene id: 28135:EL210_RS02650
uniprot id: A0A3S4V8F1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

28135:EL210 RS08420
gene id: 28135:EL210_RS08420
uniprot id: A0A3S5EPC1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

28135:EL210 RS12655
gene id: 28135:EL210_RS12655
uniprot id: A0A448L9B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

28135:EL210 RS06130
gene id: 28135:EL210_RS06130
uniprot id: A0A3S4T1Y9
names: Similarity
messages: Belongs to the type IA topoisomerase family.

28135:EL210 RS09110
gene id: 28135:EL210_RS09110
uniprot id: A0A3S4UMG5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

28135:EL210 RS07275
gene id: 28135:EL210_RS07275
uniprot id: A0A3S4TXH1
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

28135:EL210 RS08695
gene id: 28135:EL210_RS08695
uniprot id: A0A3S4X2N6
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS01075
gene id: 28135:EL210_RS01075
uniprot id: A0A448L2M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS04615
gene id: 28135:EL210_RS04615
uniprot id: A0A448L4R2
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

28135:EL210 RS08805
gene id: 28135:EL210_RS08805
uniprot id: A0A448L7E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

28135:EL210 RS09545
gene id: 28135:EL210_RS09545
uniprot id: A0A3S4TC65
names: Subcellular Location Annotation
messages: Cytoplasm

28135:EL210 RS12150
gene id: 28135:EL210_RS12150
uniprot id: A0A448L907
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

28135:EL210 RS10855
gene id: 28135:EL210_RS10855
uniprot id: A0A3S4TCK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS12595
gene id: 28135:EL210_RS12595
uniprot id: A0A3S4TZ63
names: Similarity
messages: Belongs to the SusD family.

28135:EL210 RS07585
gene id: 28135:EL210_RS07585
uniprot id: A0A448L6J0
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

28135:EL210 RS07170
gene id: 28135:EL210_RS07170
uniprot id: A0A3S4TXG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

28135:EL210 RS09395
gene id: 28135:EL210_RS09395
uniprot id: A0A3S4TFQ3
names: Similarity
messages: Belongs to the peptidase S49 family.

28135:EL210 RS02835
gene id: 28135:EL210_RS02835
uniprot id: A0A3S4T114
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

28135:EL210 RS11045
gene id: 28135:EL210_RS11045
uniprot id: A0A448L8G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

28135:EL210 RS08900
gene id: 28135:EL210_RS08900
uniprot id: A0A3S4T6E7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

28135:EL210 RS05450
gene id: 28135:EL210_RS05450
uniprot id: A0A448L595
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

28135:EL210 RS00200
gene id: 28135:EL210_RS00200
uniprot id: A0A448L2A7
names: Similarity
messages: Belongs to the SusD family.

28135:EL210 RS02610
gene id: 28135:EL210_RS02610
uniprot id: A0A3S4X5R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS03895
gene id: 28135:EL210_RS03895
uniprot id: A0A3S4TDV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

28135:EL210 RS10555
gene id: 28135:EL210_RS10555
uniprot id: A0A3S5EPE4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS08505
gene id: 28135:EL210_RS08505
uniprot id: A0A448L6W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

28135:EL210 RS01090
gene id: 28135:EL210_RS01090
uniprot id: A0A448L2S7
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

28135:EL210 RS02930
gene id: 28135:EL210_RS02930
uniprot id: A0A448L3R1
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

28135:EL210 RS10755
gene id: 28135:EL210_RS10755
uniprot id: A0A3S5EPE6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

28135:EL210 RS11640
gene id: 28135:EL210_RS11640
uniprot id: A0A3S4T3S8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

28135:EL210 RS11540
gene id: 28135:EL210_RS11540
uniprot id: A0A448L8P1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

28135:EL210 RS10185
gene id: 28135:EL210_RS10185
uniprot id: A0A3S4TYF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

28135:EL210 RS08525
gene id: 28135:EL210_RS08525
uniprot id: A0A3S5EPC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

28135:EL210 RS08725
gene id: 28135:EL210_RS08725
uniprot id: A0A448L729
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS00900
gene id: 28135:EL210_RS00900
uniprot id: A0A448L2Q8
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS01300
gene id: 28135:EL210_RS01300
uniprot id: A0A3S5EP43
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

28135:EL210 RS04140
gene id: 28135:EL210_RS04140
uniprot id: A0A448L4E8
names: Similarity
messages: Belongs to the Skp family.

28135:EL210 RS02365
gene id: 28135:EL210_RS02365
uniprot id: A0A448L3G7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

28135:EL210 RS08855
gene id: 28135:EL210_RS08855
uniprot id: A0A3S4TXY0
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS08790
gene id: 28135:EL210_RS08790
uniprot id: A0A3S4X2Q2
names: Similarity
messages: Belongs to the peptidase C69 family.

28135:EL210 RS09735
gene id: 28135:EL210_RS09735
uniprot id: A0A448L7W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

28135:EL210 RS07080
gene id: 28135:EL210_RS07080
uniprot id: A0A3S4T298
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

28135:EL210 RS08430
gene id: 28135:EL210_RS08430
uniprot id: A0A448L6Z8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

28135:EL210 RS05585
gene id: 28135:EL210_RS05585
uniprot id: A0A448L5A0
names: Similarity
messages: Belongs to the type IA topoisomerase family.

28135:EL210 RS11915
gene id: 28135:EL210_RS11915
uniprot id: A0A3S4TGH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

28135:EL210 RS07425
gene id: 28135:EL210_RS07425
uniprot id: A0A448L6N3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

28135:EL210 RS00225
gene id: 28135:EL210_RS00225
uniprot id: A0A3S4X030
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

28135:EL210 RS07215
gene id: 28135:EL210_RS07215
uniprot id: A0A448L677
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS07900
gene id: 28135:EL210_RS07900
uniprot id: A0A3S5EPB5
names: Similarity
messages: Belongs to the transketolase family.

28135:EL210 RS01540
gene id: 28135:EL210_RS01540
uniprot id: A0A3S4T426
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

28135:EL210 RS04535
gene id: 28135:EL210_RS04535
uniprot id: A0A3S4T4Z7
names: Similarity
messages: Belongs to the RutC family.

28135:EL210 RS08045
gene id: 28135:EL210_RS08045
uniprot id: A0A3S4T2J0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

28135:EL210 RS00235
gene id: 28135:EL210_RS00235
uniprot id: A0A448L2A5
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS07100
gene id: 28135:EL210_RS07100
uniprot id: A0A3S4X7B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

28135:EL210 RS10580
gene id: 28135:EL210_RS10580
uniprot id: A0A3S4T6W5
names: Similarity
messages: Belongs to the XseB family.

28135:EL210 RS13260
gene id: 28135:EL210_RS13260
uniprot id: A0A3S4TDC0
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

28135:EL210 RS13285
gene id: 28135:EL210_RS13285
uniprot id: A0A3S4TGX7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

28135:EL210 RS01535
gene id: 28135:EL210_RS01535
uniprot id: A0A448L321
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

28135:EL210 RS05135
gene id: 28135:EL210_RS05135
uniprot id: A0A448L527
names: Similarity
messages: Belongs to the peptidase C1 family.

28135:EL210 RS01630
gene id: 28135:EL210_RS01630
uniprot id: A0A3S4TD62
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

28135:EL210 RS11750
gene id: 28135:EL210_RS11750
uniprot id: A0A3S4T781
names: Similarity
messages: Belongs to the bacteroidetes fimbrillin superfamily. FimB/Mfa2 family.

28135:EL210 RS08550
gene id: 28135:EL210_RS08550
uniprot id: A0A3S4T6B8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

28135:EL210 RS02140
gene id: 28135:EL210_RS02140
uniprot id: A0A3S4TW03
names: Caution
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS02800
gene id: 28135:EL210_RS02800
uniprot id: A0A448L3Q3
names: Similarity
messages: Belongs to the sigma-54 factor family.

28135:EL210 RS10675
gene id: 28135:EL210_RS10675
uniprot id: A0A3S4TCI6
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

28135:EL210 RS04155
gene id: 28135:EL210_RS04155
uniprot id: A0A3S4V8X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

28135:EL210 RS11895
gene id: 28135:EL210_RS11895
uniprot id: A0A3S4UNB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

28135:EL210 RS07840
gene id: 28135:EL210_RS07840
uniprot id: A0A448L6J7
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS03505
gene id: 28135:EL210_RS03505
uniprot id: A0A448L431
names: Similarity
messages: Belongs to the SusD family.

28135:EL210 RS10620
gene id: 28135:EL210_RS10620
uniprot id: A0A3S4TG08
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

28135:EL210 RS00730
gene id: 28135:EL210_RS00730
uniprot id: A0A448L2G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

28135:EL210 RS04700
gene id: 28135:EL210_RS04700
uniprot id: A0A448L4W2
names: Subcellular Location Annotation
messages: Membrane

28135:EL210 RS04095
gene id: 28135:EL210_RS04095
uniprot id: A0A448L4E6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

28135:EL210 RS11835
gene id: 28135:EL210_RS11835
uniprot id: A0A448L8Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

28135:EL210 RS04910
gene id: 28135:EL210_RS04910
uniprot id: A0A3S4T541
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS12385
gene id: 28135:EL210_RS12385
uniprot id: A0A448L974
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

28135:EL210 RS06470
gene id: 28135:EL210_RS06470
uniprot id: A0A448L5T2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

28135:EL210 RS09610
gene id: 28135:EL210_RS09610
uniprot id: A0A448L7L0
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

28135:EL210 RS06205
gene id: 28135:EL210_RS06205
uniprot id: A0A448L5N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

28135:EL210 RS02085
gene id: 28135:EL210_RS02085
uniprot id: A0A3S4T474
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS00790
gene id: 28135:EL210_RS00790
uniprot id: A0A448L2K8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

28135:EL210 RS00785
gene id: 28135:EL210_RS00785
uniprot id: A0A3S4V7W0
names: Similarity
messages: Belongs to the transglycosylase Slt family.

28135:EL210 RS08865
gene id: 28135:EL210_RS08865
uniprot id: A0A448L762
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

28135:EL210 RS08735
gene id: 28135:EL210_RS08735
uniprot id: A0A3S4T2R2
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

28135:EL210 RS10960
gene id: 28135:EL210_RS10960
uniprot id: A0A448L8M1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

28135:EL210 RS04875
gene id: 28135:EL210_RS04875
uniprot id: A0A448L4Y1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

28135:EL210 RS00725
gene id: 28135:EL210_RS00725
uniprot id: A0A448L2F8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28135:EL210 RS02050
gene id: 28135:EL210_RS02050
uniprot id: A0A448L3B7
names: Similarity
messages: Belongs to the ribF family.

28135:EL210 RS06455
gene id: 28135:EL210_RS06455
uniprot id: A0A3S4X1Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

28135:EL210 RS12660
gene id: 28135:EL210_RS12660
uniprot id: A0A3S4TZ70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

28135:EL210 RS03155
gene id: 28135:EL210_RS03155
uniprot id: A0A3S4X0X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

28135:EL210 RS09175
gene id: 28135:EL210_RS09175
uniprot id: A0A448L7B5
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

28135:EL210 RS07545
gene id: 28135:EL210_RS07545
uniprot id: A0A3S4T607
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

28135:EL210 RS06965
gene id: 28135:EL210_RS06965
uniprot id: A0A448L630
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

28135:EL210 RS08455
gene id: 28135:EL210_RS08455
uniprot id: A0A448L6Y4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

28135:EL210 RS02615
gene id: 28135:EL210_RS02615
uniprot id: A0A3S5EP56
names: Similarity
messages: Belongs to the SusD family.

28135:EL210 RS10725
gene id: 28135:EL210_RS10725
uniprot id: A0A3S4T3H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

28135:EL210 RS11715
gene id: 28135:EL210_RS11715
uniprot id: A0A3S4T3T5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

28135:EL210 RS02195
gene id: 28135:EL210_RS02195
uniprot id: A0A448L3B5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28135:EL210 RS02920
gene id: 28135:EL210_RS02920
uniprot id: A0A448L3S8
names: Similarity
messages: Belongs to the glutamine synthetase family.

28135:EL210 RS07660
gene id: 28135:EL210_RS07660
uniprot id: A0A3S4VA04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.