28091:EL309 RS09770
gene id: 28091:EL309_RS09770
uniprot id: A0A448VQG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

28091:EL309 RS07075
gene id: 28091:EL309_RS07075
uniprot id: A0A3S5AB59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

28091:EL309 RS09225
gene id: 28091:EL309_RS09225
uniprot id: A0A3S5C4J5
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

28091:EL309 RS05935
gene id: 28091:EL309_RS05935
uniprot id: A0A448VNP8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

28091:EL309 RS03700
gene id: 28091:EL309_RS03700
uniprot id: A0A3S5C3M9
names: Similarity
messages: Belongs to the PrpF family.

28091:EL309 RS03160
gene id: 28091:EL309_RS03160
uniprot id: A0A3S4Z2Z9
names: Similarity
messages: Belongs to the YciI family.

28091:EL309 RS04985
gene id: 28091:EL309_RS04985
uniprot id: A0A3S5AA60
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

28091:EL309 RS08495
gene id: 28091:EL309_RS08495
uniprot id: A0A3S4YSQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

28091:EL309 RS03760
gene id: 28091:EL309_RS03760
uniprot id: A0A3S4Z817
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

28091:EL309 RS06130
gene id: 28091:EL309_RS06130
uniprot id: A0A448VNK9
names: Similarity
messages: Belongs to the BolA/IbaG family.

28091:EL309 RS06555
gene id: 28091:EL309_RS06555
uniprot id: A0A3S5F9S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

28091:EL309 RS07755
gene id: 28091:EL309_RS07755
uniprot id: A0A3S4YSF7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

28091:EL309 RS04215
gene id: 28091:EL309_RS04215
uniprot id: A0A3S5C3S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

28091:EL309 RS01275
gene id: 28091:EL309_RS01275
uniprot id: A0A448VIF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

28091:EL309 RS00395
gene id: 28091:EL309_RS00395
uniprot id: A0A448VHD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

28091:EL309 RS01040
gene id: 28091:EL309_RS01040
uniprot id: A0A3S4Z1K0
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

28091:EL309 RS06510
gene id: 28091:EL309_RS06510
uniprot id: A0A448VNS1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

28091:EL309 RS04000
gene id: 28091:EL309_RS04000
uniprot id: A0A3S4Z3G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

28091:EL309 RS09290
gene id: 28091:EL309_RS09290
uniprot id: A0A448VQ67
names: Similarity
messages: Belongs to the GppA/Ppx family.

28091:EL309 RS08080
gene id: 28091:EL309_RS08080
uniprot id: A0A448VPH2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

28091:EL309 RS04945
gene id: 28091:EL309_RS04945
uniprot id: A0A448VMI7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

28091:EL309 RS00945
gene id: 28091:EL309_RS00945
uniprot id: A0A448VI11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

28091:EL309 RS06490
gene id: 28091:EL309_RS06490
uniprot id: A0A448VNN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

28091:EL309 RS05725
gene id: 28091:EL309_RS05725
uniprot id: A0A448VNB8
names: Similarity
messages: Belongs to the GARS family.

28091:EL309 RS10285
gene id: 28091:EL309_RS10285
uniprot id: A0A448VQQ9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

28091:EL309 RS06750
gene id: 28091:EL309_RS06750
uniprot id: A0A3S5C495
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

28091:EL309 RS08250
gene id: 28091:EL309_RS08250
uniprot id: A0A3S5B5Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

28091:EL309 RS08785
gene id: 28091:EL309_RS08785
uniprot id: A0A448VQ42
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS04560
gene id: 28091:EL309_RS04560
uniprot id: A0A448VM51
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

28091:EL309 RS04675
gene id: 28091:EL309_RS04675
uniprot id: A0A448VMF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

28091:EL309 RS04075
gene id: 28091:EL309_RS04075
uniprot id: A0A448VLM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

28091:EL309 RS08400
gene id: 28091:EL309_RS08400
uniprot id: A0A448VPQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

28091:EL309 RS05480
gene id: 28091:EL309_RS05480
uniprot id: A0A448VN15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

28091:EL309 RS08190
gene id: 28091:EL309_RS08190
uniprot id: A0A448VPJ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

28091:EL309 RS10355
gene id: 28091:EL309_RS10355
uniprot id: A0A3S5B6B3
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

28091:EL309 RS04835
gene id: 28091:EL309_RS04835
uniprot id: A0A448VMF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

28091:EL309 RS05580
gene id: 28091:EL309_RS05580
uniprot id: A0A3S4Z994
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

28091:EL309 RS08355
gene id: 28091:EL309_RS08355
uniprot id: A0A448VPN0
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS07350
gene id: 28091:EL309_RS07350
uniprot id: A0A3S5CAP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

28091:EL309 RS10180
gene id: 28091:EL309_RS10180
uniprot id: A0A3S4ZEP5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

28091:EL309 RS08415
gene id: 28091:EL309_RS08415
uniprot id: A0A3S4ZA91
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

28091:EL309 RS07015
gene id: 28091:EL309_RS07015
uniprot id: A0A3S4ZDQ4
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

28091:EL309 RS02980
gene id: 28091:EL309_RS02980
uniprot id: A0A3S5C9U1
names: Similarity
messages: Belongs to the LOG family.

28091:EL309 RS08320
gene id: 28091:EL309_RS08320
uniprot id: A0A448VPQ6
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

28091:EL309 RS01295
gene id: 28091:EL309_RS01295
uniprot id: A0A3S5B261
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

28091:EL309 RS02760
gene id: 28091:EL309_RS02760
uniprot id: A0A3S4ZBS3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

28091:EL309 RS04765
gene id: 28091:EL309_RS04765
uniprot id: A0A3S5CA90
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

28091:EL309 RS02230
gene id: 28091:EL309_RS02230
uniprot id: A0A3S5A878
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

28091:EL309 RS04860
gene id: 28091:EL309_RS04860
uniprot id: A0A3S5CAA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

28091:EL309 RS01270
gene id: 28091:EL309_RS01270
uniprot id: A0A448VIF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

28091:EL309 RS03275
gene id: 28091:EL309_RS03275
uniprot id: A0A448VKS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

28091:EL309 RS03455
gene id: 28091:EL309_RS03455
uniprot id: A0A448VKW9
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS07665
gene id: 28091:EL309_RS07665
uniprot id: A0A448VP97
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

28091:EL309 RS01490
gene id: 28091:EL309_RS01490
uniprot id: A0A3S4Z6J3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

28091:EL309 RS07145
gene id: 28091:EL309_RS07145
uniprot id: A0A448VP16
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

28091:EL309 RS02270
gene id: 28091:EL309_RS02270
uniprot id: A0A448VJK9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

28091:EL309 RS04990
gene id: 28091:EL309_RS04990
uniprot id: A0A3S4ZCY5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.

28091:EL309 RS04680
gene id: 28091:EL309_RS04680
uniprot id: A0A3S4ZCT4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

28091:EL309 RS04580
gene id: 28091:EL309_RS04580
uniprot id: A0A448VM46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

28091:EL309 RS06395
gene id: 28091:EL309_RS06395
uniprot id: A0A3S5CAK0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

28091:EL309 RS04355
gene id: 28091:EL309_RS04355
uniprot id: A0A448VLW4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

28091:EL309 RS00385
gene id: 28091:EL309_RS00385
uniprot id: A0A448VHC3
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

28091:EL309 RS08930
gene id: 28091:EL309_RS08930
uniprot id: A0A3S5C4I5
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

28091:EL309 RS08730
gene id: 28091:EL309_RS08730
uniprot id: A0A3S4YSR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

28091:EL309 RS01485
gene id: 28091:EL309_RS01485
uniprot id: A0A3S5F9H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

28091:EL309 RS06300
gene id: 28091:EL309_RS06300
uniprot id: A0A448VNW7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

28091:EL309 RS02815
gene id: 28091:EL309_RS02815
uniprot id: A0A3S5B389
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

28091:EL309 RS09230
gene id: 28091:EL309_RS09230
uniprot id: A0A3S5ABW7
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

28091:EL309 RS06330
gene id: 28091:EL309_RS06330
uniprot id: A0A448VNP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.

28091:EL309 RS01565
gene id: 28091:EL309_RS01565
uniprot id: A0A3S5C9F8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

28091:EL309 RS01875
gene id: 28091:EL309_RS01875
uniprot id: A0A3S5C373
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

28091:EL309 RS03845
gene id: 28091:EL309_RS03845
uniprot id: A0A3S5F9N2
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

28091:EL309 RS09085
gene id: 28091:EL309_RS09085
uniprot id: A0A3S5B5Y6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

28091:EL309 RS04325
gene id: 28091:EL309_RS04325
uniprot id: A0A3S5CA53
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

28091:EL309 RS02620
gene id: 28091:EL309_RS02620
uniprot id: A0A3S5B348
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

28091:EL309 RS09845
gene id: 28091:EL309_RS09845
uniprot id: A0A3S4ZAM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

28091:EL309 RS08240
gene id: 28091:EL309_RS08240
uniprot id: A0A3S5ABL1
names: Similarity
messages: Belongs to the fabD family.

28091:EL309 RS01405
gene id: 28091:EL309_RS01405
uniprot id: A0A448VIK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

28091:EL309 RS08425
gene id: 28091:EL309_RS08425
uniprot id: A0A448VPS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters.

28091:EL309 RS06200
gene id: 28091:EL309_RS06200
uniprot id: A0A448VNF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

28091:EL309 RS07435
gene id: 28091:EL309_RS07435
uniprot id: A0A3S5F9T7
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

28091:EL309 RS10585
gene id: 28091:EL309_RS10585
uniprot id: A0A448VQU7
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

28091:EL309 RS05300
gene id: 28091:EL309_RS05300
uniprot id: A0A3S5CAE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

28091:EL309 RS09200
gene id: 28091:EL309_RS09200
uniprot id: A0A3S5F9V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

28091:EL309 RS04165
gene id: 28091:EL309_RS04165
uniprot id: A0A3S5CA39
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

28091:EL309 RS09250
gene id: 28091:EL309_RS09250
uniprot id: A0A3S5B606
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

28091:EL309 RS10570
gene id: 28091:EL309_RS10570
uniprot id: A0A3S4ZN32
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

28091:EL309 RS10450
gene id: 28091:EL309_RS10450
uniprot id: A0A448VQV7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

28091:EL309 RS00550
gene id: 28091:EL309_RS00550
uniprot id: A0A3S4Z5U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

28091:EL309 RS05715
gene id: 28091:EL309_RS05715
uniprot id: A0A448VND7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

28091:EL309 RS09415
gene id: 28091:EL309_RS09415
uniprot id: A0A448VQC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

28091:EL309 RS04565
gene id: 28091:EL309_RS04565
uniprot id: A0A3S4Z3S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

28091:EL309 RS07495
gene id: 28091:EL309_RS07495
uniprot id: A0A448VP63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

28091:EL309 RS05825
gene id: 28091:EL309_RS05825
uniprot id: A0A3S5CAH7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

28091:EL309 RS05735
gene id: 28091:EL309_RS05735
uniprot id: A0A448VN67
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

28091:EL309 RS08775
gene id: 28091:EL309_RS08775
uniprot id: A0A3S5ABR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

28091:EL309 RS06220
gene id: 28091:EL309_RS06220
uniprot id: A0A3S5C473
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

28091:EL309 RS05365
gene id: 28091:EL309_RS05365
uniprot id: A0A3S4ZD68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Slam family.
messages: Cell outer membrane
messages: Membrane

28091:EL309 RS06650
gene id: 28091:EL309_RS06650
uniprot id: A0A3S4Z9L2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

28091:EL309 RS05900
gene id: 28091:EL309_RS05900
uniprot id: A0A3S4ZDD5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

28091:EL309 RS04815
gene id: 28091:EL309_RS04815
uniprot id: A0A3S4Z8Q7
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

28091:EL309 RS09160
gene id: 28091:EL309_RS09160
uniprot id: A0A3S4ZEE5
names: Similarity
messages: Belongs to the YfgM family.

28091:EL309 RS09450
gene id: 28091:EL309_RS09450
uniprot id: A0A3S4ZAJ1
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS09285
gene id: 28091:EL309_RS09285
uniprot id: A0A448VQ58
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

28091:EL309 RS01720
gene id: 28091:EL309_RS01720
uniprot id: A0A448VIY8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

28091:EL309 RS03890
gene id: 28091:EL309_RS03890
uniprot id: A0A3S5C3P9
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

28091:EL309 RS07950
gene id: 28091:EL309_RS07950
uniprot id: A0A3S5B5K5
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS04305
gene id: 28091:EL309_RS04305
uniprot id: A0A3S4YQX5
names: Similarity
messages: Belongs to the catalase family.

28091:EL309 RS06755
gene id: 28091:EL309_RS06755
uniprot id: A0A448VNW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

28091:EL309 RS08095
gene id: 28091:EL309_RS08095
uniprot id: A0A3S4ZE29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

28091:EL309 RS04220
gene id: 28091:EL309_RS04220
uniprot id: A0A3S5A9L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

28091:EL309 RS06645
gene id: 28091:EL309_RS06645
uniprot id: A0A3S4Z4N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

28091:EL309 RS06580
gene id: 28091:EL309_RS06580
uniprot id: A0A3S5C484
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

28091:EL309 RS10015
gene id: 28091:EL309_RS10015
uniprot id: A0A448VQI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

28091:EL309 RS04790
gene id: 28091:EL309_RS04790
uniprot id: A0A448VMC5
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

28091:EL309 RS07540
gene id: 28091:EL309_RS07540
uniprot id: A0A448VP58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

28091:EL309 RS00820
gene id: 28091:EL309_RS00820
uniprot id: A0A3S4ZAG1
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

28091:EL309 RS06730
gene id: 28091:EL309_RS06730
uniprot id: A0A448VNT4
names: Similarity
messages: Belongs to the GSP E family.

28091:EL309 RS09775
gene id: 28091:EL309_RS09775
uniprot id: A0A3S5C4L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

28091:EL309 RS09350
gene id: 28091:EL309_RS09350
uniprot id: A0A3S5C4J8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS10260
gene id: 28091:EL309_RS10260
uniprot id: A0A448VQK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

28091:EL309 RS00525
gene id: 28091:EL309_RS00525
uniprot id: A0A3S4YNA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

28091:EL309 RS06710
gene id: 28091:EL309_RS06710
uniprot id: A0A3S4ZLZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

28091:EL309 RS02335
gene id: 28091:EL309_RS02335
uniprot id: A0A3S4YPN3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

28091:EL309 RS04900
gene id: 28091:EL309_RS04900
uniprot id: A0A3S5B4F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

28091:EL309 RS06135
gene id: 28091:EL309_RS06135
uniprot id: A0A448VNN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

28091:EL309 RS03195
gene id: 28091:EL309_RS03195
uniprot id: A0A3S4Z310
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

28091:EL309 RS10245
gene id: 28091:EL309_RS10245
uniprot id: A0A3S4ZEQ7
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

28091:EL309 RS01945
gene id: 28091:EL309_RS01945
uniprot id: A0A448VJ70
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

28091:EL309 RS03445
gene id: 28091:EL309_RS03445
uniprot id: A0A3S4YQE6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

28091:EL309 RS02930
gene id: 28091:EL309_RS02930
uniprot id: A0A448VKA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

28091:EL309 RS04080
gene id: 28091:EL309_RS04080
uniprot id: A0A3S5A9G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

28091:EL309 RS06250
gene id: 28091:EL309_RS06250
uniprot id: A0A3S4YRY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

28091:EL309 RS00145
gene id: 28091:EL309_RS00145
uniprot id: A0A3S5C908
names: Similarity
messages: Belongs to the barstar family.

28091:EL309 RS02275
gene id: 28091:EL309_RS02275
uniprot id: A0A3S5F9J6
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

28091:EL309 RS06810
gene id: 28091:EL309_RS06810
uniprot id: A0A3S4Z4Q1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

28091:EL309 RS05055
gene id: 28091:EL309_RS05055
uniprot id: A0A3S4ZD05
names: Similarity
messages: Belongs to the RecJ family.

28091:EL309 RS09405
gene id: 28091:EL309_RS09405
uniprot id: A0A3S4YSX9
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

28091:EL309 RS05310
gene id: 28091:EL309_RS05310
uniprot id: A0A448VMY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

28091:EL309 RS06035
gene id: 28091:EL309_RS06035
uniprot id: A0A3S4YRW4
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS01850
gene id: 28091:EL309_RS01850
uniprot id: A0A3S4YPA5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

28091:EL309 RS08075
gene id: 28091:EL309_RS08075
uniprot id: A0A3S4ZA44
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

28091:EL309 RS03250
gene id: 28091:EL309_RS03250
uniprot id: A0A448VKR0
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

28091:EL309 RS04255
gene id: 28091:EL309_RS04255
uniprot id: A0A3S4ZKU6
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

28091:EL309 RS05855
gene id: 28091:EL309_RS05855
uniprot id: A0A3S4Z9C9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

28091:EL309 RS08215
gene id: 28091:EL309_RS08215
uniprot id: A0A3S5F9U6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

28091:EL309 RS05785
gene id: 28091:EL309_RS05785
uniprot id: A0A448VN81
names: Similarity
messages: Belongs to the YjdM family.

28091:EL309 RS07485
gene id: 28091:EL309_RS07485
uniprot id: A0A448VPA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

28091:EL309 RS07945
gene id: 28091:EL309_RS07945
uniprot id: A0A448VPN6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

28091:EL309 RS08790
gene id: 28091:EL309_RS08790
uniprot id: A0A3S5B5W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

28091:EL309 RS03165
gene id: 28091:EL309_RS03165
uniprot id: A0A3S5C3I5
names: Similarity
messages: Belongs to the BolA/IbaG family.

28091:EL309 RS08405
gene id: 28091:EL309_RS08405
uniprot id: A0A3S4Z5A2
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

28091:EL309 RS09480
gene id: 28091:EL309_RS09480
uniprot id: A0A3S4ZEH4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

28091:EL309 RS04490
gene id: 28091:EL309_RS04490
uniprot id: A0A448VM07
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

28091:EL309 RS06695
gene id: 28091:EL309_RS06695
uniprot id: A0A3S5B558
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

28091:EL309 RS06445
gene id: 28091:EL309_RS06445
uniprot id: A0A3S4ZEI5
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS07550
gene id: 28091:EL309_RS07550
uniprot id: A0A3S4Z4Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

28091:EL309 RS01760
gene id: 28091:EL309_RS01760
uniprot id: A0A448VJ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

28091:EL309 RS09275
gene id: 28091:EL309_RS09275
uniprot id: A0A3S4ZMS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

28091:EL309 RS00495
gene id: 28091:EL309_RS00495
uniprot id: A0A448VHI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

28091:EL309 RS06015
gene id: 28091:EL309_RS06015
uniprot id: A0A3S5B4Y4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

28091:EL309 RS01210
gene id: 28091:EL309_RS01210
uniprot id: A0A3S5C9B5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

28091:EL309 RS05105
gene id: 28091:EL309_RS05105
uniprot id: A0A3S4YRG0
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

28091:EL309 RS07835
gene id: 28091:EL309_RS07835
uniprot id: A0A448VPG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

28091:EL309 RS04410
gene id: 28091:EL309_RS04410
uniprot id: A0A448VLY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

28091:EL309 RS00470
gene id: 28091:EL309_RS00470
uniprot id: A0A448VHH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

28091:EL309 RS06195
gene id: 28091:EL309_RS06195
uniprot id: A0A3S4Z4I9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

28091:EL309 RS04935
gene id: 28091:EL309_RS04935
uniprot id: A0A3S5B4G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

28091:EL309 RS02080
gene id: 28091:EL309_RS02080
uniprot id: A0A3S4YPG8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS01360
gene id: 28091:EL309_RS01360
uniprot id: A0A3S4Z6F5
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

28091:EL309 RS05870
gene id: 28091:EL309_RS05870
uniprot id: A0A448VNG7
names: Similarity
messages: Belongs to the ArsC family.

28091:EL309 RS04345
gene id: 28091:EL309_RS04345
uniprot id: A0A448VLV0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

28091:EL309 RS08990
gene id: 28091:EL309_RS08990
uniprot id: A0A448VQ80
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

28091:EL309 RS03045
gene id: 28091:EL309_RS03045
uniprot id: A0A448VKF4
names: Similarity
messages: Belongs to the RutC family.

28091:EL309 RS03820
gene id: 28091:EL309_RS03820
uniprot id: A0A3S5B3T6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

28091:EL309 RS03345
gene id: 28091:EL309_RS03345
uniprot id: A0A448VKT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

28091:EL309 RS01305
gene id: 28091:EL309_RS01305
uniprot id: A0A448VIE9
names: Similarity
messages: Belongs to the UPF0250 family.

28091:EL309 RS08935
gene id: 28091:EL309_RS08935
uniprot id: A0A3S5ABT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

28091:EL309 RS04820
gene id: 28091:EL309_RS04820
uniprot id: A0A3S5C3X3
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family. HpaC subfamily.

28091:EL309 RS08900
gene id: 28091:EL309_RS08900
uniprot id: A0A3S4YST5
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

28091:EL309 RS00510
gene id: 28091:EL309_RS00510
uniprot id: A0A448VHH2
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

28091:EL309 RS08560
gene id: 28091:EL309_RS08560
uniprot id: A0A448VPR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

28091:EL309 RS01585
gene id: 28091:EL309_RS01585
uniprot id: A0A448VIU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28091:EL309 RS04800
gene id: 28091:EL309_RS04800
uniprot id: A0A448VMC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

28091:EL309 RS08735
gene id: 28091:EL309_RS08735
uniprot id: A0A3S4ZMM3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

28091:EL309 RS02665
gene id: 28091:EL309_RS02665
uniprot id: A0A3S4YPV5
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.

28091:EL309 RS08440
gene id: 28091:EL309_RS08440
uniprot id: A0A448VPN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

28091:EL309 RS07260
gene id: 28091:EL309_RS07260
uniprot id: A0A448VP18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

28091:EL309 RS03085
gene id: 28091:EL309_RS03085
uniprot id: A0A3S4ZBY9
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS07760
gene id: 28091:EL309_RS07760
uniprot id: A0A448VPA6
names: Subcellular Location Annotation
messages: Secreted

28091:EL309 RS05330
gene id: 28091:EL309_RS05330
uniprot id: A0A3S4YRM0
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

28091:EL309 RS08460
gene id: 28091:EL309_RS08460
uniprot id: A0A448VPP8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

28091:EL309 RS02985
gene id: 28091:EL309_RS02985
uniprot id: A0A3S4Z2W2
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

28091:EL309 RS08010
gene id: 28091:EL309_RS08010
uniprot id: A0A3S5C4E9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

28091:EL309 RS07405
gene id: 28091:EL309_RS07405
uniprot id: A0A448VP66
names: Similarity
messages: Belongs to the ABC transporter superfamily.

28091:EL309 RS03370
gene id: 28091:EL309_RS03370
uniprot id: A0A3S4Z346
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

28091:EL309 RS07785
gene id: 28091:EL309_RS07785
uniprot id: A0A448VPQ3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the trans-sulfuration enzymes family.

28091:EL309 RS04470
gene id: 28091:EL309_RS04470
uniprot id: A0A448VM29
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

28091:EL309 RS08845
gene id: 28091:EL309_RS08845
uniprot id: A0A3S5F9V2
names: Similarity
messages: Belongs to the UDPGP type 2 family.

28091:EL309 RS10590
gene id: 28091:EL309_RS10590
uniprot id: A0A3S5F9X0
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

28091:EL309 RS06885
gene id: 28091:EL309_RS06885
uniprot id: A0A448VNX7
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS01985
gene id: 28091:EL309_RS01985
uniprot id: A0A3S4YPE2
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

28091:EL309 RS07320
gene id: 28091:EL309_RS07320
uniprot id: A0A448VP72
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS08035
gene id: 28091:EL309_RS08035
uniprot id: A0A448VPG7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

28091:EL309 RS04665
gene id: 28091:EL309_RS04665
uniprot id: A0A448VM82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

28091:EL309 RS04605
gene id: 28091:EL309_RS04605
uniprot id: A0A448VM57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

28091:EL309 RS08305
gene id: 28091:EL309_RS08305
uniprot id: A0A3S4Z594
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

28091:EL309 RS03735
gene id: 28091:EL309_RS03735
uniprot id: A0A448VL84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

28091:EL309 RS05600
gene id: 28091:EL309_RS05600
uniprot id: A0A3S5AAM4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS05290
gene id: 28091:EL309_RS05290
uniprot id: A0A3S5B4P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

28091:EL309 RS00480
gene id: 28091:EL309_RS00480
uniprot id: A0A448VHH6
names: Similarity
messages: Belongs to the thioredoxin family.

28091:EL309 RS10085
gene id: 28091:EL309_RS10085
uniprot id: A0A3S4YT45
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS10010
gene id: 28091:EL309_RS10010
uniprot id: A0A3S4ZMY5
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

28091:EL309 RS07440
gene id: 28091:EL309_RS07440
uniprot id: A0A448VP35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28091:EL309 RS07960
gene id: 28091:EL309_RS07960
uniprot id: A0A448VPD6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

28091:EL309 RS04070
gene id: 28091:EL309_RS04070
uniprot id: A0A3S5C3R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

28091:EL309 RS05645
gene id: 28091:EL309_RS05645
uniprot id: A0A448VN90
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

28091:EL309 RS08975
gene id: 28091:EL309_RS08975
uniprot id: A0A448VPZ8
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

28091:EL309 RS05665
gene id: 28091:EL309_RS05665
uniprot id: A0A3S5AAP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

28091:EL309 RS06635
gene id: 28091:EL309_RS06635
uniprot id: A0A3S5F9S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

28091:EL309 RS04595
gene id: 28091:EL309_RS04595
uniprot id: A0A448VM65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

28091:EL309 RS10205
gene id: 28091:EL309_RS10205
uniprot id: A0A448VQZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

28091:EL309 RS05770
gene id: 28091:EL309_RS05770
uniprot id: A0A3S4Z9B9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

28091:EL309 RS01645
gene id: 28091:EL309_RS01645
uniprot id: A0A448VIV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

28091:EL309 RS09645
gene id: 28091:EL309_RS09645
uniprot id: A0A448VQB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28091:EL309 RS01045
gene id: 28091:EL309_RS01045
uniprot id: A0A3S5A7A1
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

28091:EL309 RS09150
gene id: 28091:EL309_RS09150
uniprot id: A0A448VQB0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

28091:EL309 RS08140
gene id: 28091:EL309_RS08140
uniprot id: A0A448VPM0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

28091:EL309 RS03765
gene id: 28091:EL309_RS03765
uniprot id: A0A448VL89
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

28091:EL309 RS00275
gene id: 28091:EL309_RS00275
uniprot id: A0A448VH92
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS08155
gene id: 28091:EL309_RS08155
uniprot id: A0A448VPW9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

28091:EL309 RS10560
gene id: 28091:EL309_RS10560
uniprot id: A0A448VR27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

28091:EL309 RS10315
gene id: 28091:EL309_RS10315
uniprot id: A0A448VQT3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

28091:EL309 RS10025
gene id: 28091:EL309_RS10025
uniprot id: A0A448VQJ9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS07180
gene id: 28091:EL309_RS07180
uniprot id: A0A448VPC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

28091:EL309 RS07115
gene id: 28091:EL309_RS07115
uniprot id: A0A3S4ZDR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

28091:EL309 RS05155
gene id: 28091:EL309_RS05155
uniprot id: A0A448VMU2
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

28091:EL309 RS04540
gene id: 28091:EL309_RS04540
uniprot id: A0A448VM30
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

28091:EL309 RS09685
gene id: 28091:EL309_RS09685
uniprot id: A0A448VQJ0
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

28091:EL309 RS07330
gene id: 28091:EL309_RS07330
uniprot id: A0A3S4YSA3
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS08485
gene id: 28091:EL309_RS08485
uniprot id: A0A3S4ZE78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

28091:EL309 RS08915
gene id: 28091:EL309_RS08915
uniprot id: A0A3S5F9V3
names: Similarity
messages: Belongs to the peptidase S66 family.

28091:EL309 RS08820
gene id: 28091:EL309_RS08820
uniprot id: A0A3S5CAW0
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

28091:EL309 RS02020
gene id: 28091:EL309_RS02020
uniprot id: A0A3S5A832
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

28091:EL309 RS02680
gene id: 28091:EL309_RS02680
uniprot id: A0A3S4Z2Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

28091:EL309 RS03895
gene id: 28091:EL309_RS03895
uniprot id: A0A3S5A9D3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

28091:EL309 RS05395
gene id: 28091:EL309_RS05395
uniprot id: A0A3S4Z496
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

28091:EL309 RS05535
gene id: 28091:EL309_RS05535
uniprot id: A0A3S4ZLK9
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

28091:EL309 RS03930
gene id: 28091:EL309_RS03930
uniprot id: A0A448VLF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

28091:EL309 RS08025
gene id: 28091:EL309_RS08025
uniprot id: A0A3S5B5L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

28091:EL309 RS10470
gene id: 28091:EL309_RS10470
uniprot id: A0A448VQP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

28091:EL309 RS06120
gene id: 28091:EL309_RS06120
uniprot id: A0A448VNF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

28091:EL309 RS01845
gene id: 28091:EL309_RS01845
uniprot id: A0A3S4ZB57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

28091:EL309 RS07660
gene id: 28091:EL309_RS07660
uniprot id: A0A448VP84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

28091:EL309 RS03860
gene id: 28091:EL309_RS03860
uniprot id: A0A3S5A9C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS01125
gene id: 28091:EL309_RS01125
uniprot id: A0A3S5C305
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

28091:EL309 RS03940
gene id: 28091:EL309_RS03940
uniprot id: A0A448VLG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

28091:EL309 RS04285
gene id: 28091:EL309_RS04285
uniprot id: A0A3S4ZCL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

28091:EL309 RS09700
gene id: 28091:EL309_RS09700
uniprot id: A0A448VQC1
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

28091:EL309 RS06235
gene id: 28091:EL309_RS06235
uniprot id: A0A448VNQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

28091:EL309 RS04205
gene id: 28091:EL309_RS04205
uniprot id: A0A448VLR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

28091:EL309 RS05200
gene id: 28091:EL309_RS05200
uniprot id: A0A448VMR4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

28091:EL309 RS04950
gene id: 28091:EL309_RS04950
uniprot id: A0A3S4ZL83
names: Subcellular Location Annotation
messages: Mitochondrion

28091:EL309 RS09665
gene id: 28091:EL309_RS09665
uniprot id: A0A3S5C4K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

28091:EL309 RS07195
gene id: 28091:EL309_RS07195
uniprot id: A0A3S5B5C2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

28091:EL309 RS10480
gene id: 28091:EL309_RS10480
uniprot id: A0A448VQW4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS09880
gene id: 28091:EL309_RS09880
uniprot id: A0A448VQH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

28091:EL309 RS09890
gene id: 28091:EL309_RS09890
uniprot id: A0A3S4YT28
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

28091:EL309 RS08505
gene id: 28091:EL309_RS08505
uniprot id: A0A448VPS7
names: Similarity
messages: Belongs to the ArsC family.

28091:EL309 RS01055
gene id: 28091:EL309_RS01055
uniprot id: A0A3S4YNQ4
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

28091:EL309 RS08150
gene id: 28091:EL309_RS08150
uniprot id: A0A3S5ABK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

28091:EL309 RS05610
gene id: 28091:EL309_RS05610
uniprot id: A0A3S5B4U2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

28091:EL309 RS09660
gene id: 28091:EL309_RS09660
uniprot id: A0A448VQD9
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

28091:EL309 RS00565
gene id: 28091:EL309_RS00565
uniprot id: A0A448VHJ3
names: Similarity
messages: Belongs to the asparaginase 1 family.

28091:EL309 RS09485
gene id: 28091:EL309_RS09485
uniprot id: A0A3S5B621
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

28091:EL309 RS09900
gene id: 28091:EL309_RS09900
uniprot id: A0A448VQU2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

28091:EL309 RS03265
gene id: 28091:EL309_RS03265
uniprot id: A0A3S5C9W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

28091:EL309 RS06190
gene id: 28091:EL309_RS06190
uniprot id: A0A3S5F9S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

28091:EL309 RS08835
gene id: 28091:EL309_RS08835
uniprot id: A0A448VQ54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

28091:EL309 RS08115
gene id: 28091:EL309_RS08115
uniprot id: A0A3S4ZMG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

28091:EL309 RS08920
gene id: 28091:EL309_RS08920
uniprot id: A0A3S4Z5E5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

28091:EL309 RS02075
gene id: 28091:EL309_RS02075
uniprot id: A0A3S4ZBB1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

28091:EL309 RS09940
gene id: 28091:EL309_RS09940
uniprot id: A0A3S4ZAN5
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

28091:EL309 RS06630
gene id: 28091:EL309_RS06630
uniprot id: A0A3S5CAK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

28091:EL309 RS07545
gene id: 28091:EL309_RS07545
uniprot id: A0A448VP73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

28091:EL309 RS06340
gene id: 28091:EL309_RS06340
uniprot id: A0A3S4Z9H7
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

28091:EL309 RS05835
gene id: 28091:EL309_RS05835
uniprot id: A0A3S5F9S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

28091:EL309 RS06285
gene id: 28091:EL309_RS06285
uniprot id: A0A448VNN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Membrane

28091:EL309 RS06515
gene id: 28091:EL309_RS06515
uniprot id: A0A3S4ZDJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

28091:EL309 RS03360
gene id: 28091:EL309_RS03360
uniprot id: A0A3S5C9X4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

28091:EL309 RS06410
gene id: 28091:EL309_RS06410
uniprot id: A0A3S4Z4L2
names: Similarity
messages: Belongs to the DprA/Smf family.

28091:EL309 RS09115
gene id: 28091:EL309_RS09115
uniprot id: A0A3S5F9V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

28091:EL309 RS04920
gene id: 28091:EL309_RS04920
uniprot id: A0A3S4Z8T3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS04315
gene id: 28091:EL309_RS04315
uniprot id: A0A448VLU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

28091:EL309 RS02195
gene id: 28091:EL309_RS02195
uniprot id: A0A448VJI3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

28091:EL309 RS03790
gene id: 28091:EL309_RS03790
uniprot id: A0A3S4ZKJ3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

28091:EL309 RS06965
gene id: 28091:EL309_RS06965
uniprot id: A0A3S5F9T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

28091:EL309 RS03825
gene id: 28091:EL309_RS03825
uniprot id: A0A3S4YQM2
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS06000
gene id: 28091:EL309_RS06000
uniprot id: A0A3S4ZDE7
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

28091:EL309 RS10495
gene id: 28091:EL309_RS10495
uniprot id: A0A3S5F9W9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS04905
gene id: 28091:EL309_RS04905
uniprot id: A0A3S5CAA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

28091:EL309 RS03340
gene id: 28091:EL309_RS03340
uniprot id: A0A3S4ZC31
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

28091:EL309 RS05085
gene id: 28091:EL309_RS05085
uniprot id: A0A3S5AA92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

28091:EL309 RS10080
gene id: 28091:EL309_RS10080
uniprot id: A0A3S5B685
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS01970
gene id: 28091:EL309_RS01970
uniprot id: A0A448VJ93
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS07280
gene id: 28091:EL309_RS07280
uniprot id: A0A3S5C4B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

28091:EL309 RS08330
gene id: 28091:EL309_RS08330
uniprot id: A0A3S5C4G7
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS00575
gene id: 28091:EL309_RS00575
uniprot id: A0A3S4YNB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

28091:EL309 RS09745
gene id: 28091:EL309_RS09745
uniprot id: A0A448VQD1
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

28091:EL309 RS07640
gene id: 28091:EL309_RS07640
uniprot id: A0A3S5ABD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

28091:EL309 RS04810
gene id: 28091:EL309_RS04810
uniprot id: A0A3S5F9Q2
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

28091:EL309 RS01975
gene id: 28091:EL309_RS01975
uniprot id: A0A448VJ96
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

28091:EL309 RS06625
gene id: 28091:EL309_RS06625
uniprot id: A0A3S4ZLY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

28091:EL309 RS06725
gene id: 28091:EL309_RS06725
uniprot id: A0A448VNQ4
names: Similarity
messages: Belongs to the GSP E family.

28091:EL309 RS08610
gene id: 28091:EL309_RS08610
uniprot id: A0A448VPT1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

28091:EL309 RS06720
gene id: 28091:EL309_RS06720
uniprot id: A0A3S5F9S9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

28091:EL309 RS09545
gene id: 28091:EL309_RS09545
uniprot id: A0A3S4Z5J8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

28091:EL309 RS09630
gene id: 28091:EL309_RS09630
uniprot id: A0A448VQH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

28091:EL309 RS00900
gene id: 28091:EL309_RS00900
uniprot id: A0A3S4Z1G6
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

28091:EL309 RS08585
gene id: 28091:EL309_RS08585
uniprot id: A0A448VQ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

28091:EL309 RS10445
gene id: 28091:EL309_RS10445
uniprot id: A0A3S5ACD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

28091:EL309 RS00410
gene id: 28091:EL309_RS00410
uniprot id: A0A448VHD1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

28091:EL309 RS08780
gene id: 28091:EL309_RS08780
uniprot id: A0A3S4ZEB0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

28091:EL309 RS08860
gene id: 28091:EL309_RS08860
uniprot id: A0A448VQ00
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

28091:EL309 RS01700
gene id: 28091:EL309_RS01700
uniprot id: A0A3S5A7U0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

28091:EL309 RS08690
gene id: 28091:EL309_RS08690
uniprot id: A0A448VPS5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

28091:EL309 RS03405
gene id: 28091:EL309_RS03405
uniprot id: A0A3S5F9M3
names: Similarity
messages: Belongs to the peptidase M1 family.

28091:EL309 RS04425
gene id: 28091:EL309_RS04425
uniprot id: A0A3S4Z3P1
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

28091:EL309 RS03075
gene id: 28091:EL309_RS03075
uniprot id: A0A3S5A8S2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS09205
gene id: 28091:EL309_RS09205
uniprot id: A0A448VQ84
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

28091:EL309 RS09830
gene id: 28091:EL309_RS09830
uniprot id: A0A3S5F9W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Slam family.
messages: Cell outer membrane
messages: Membrane

28091:EL309 RS01805
gene id: 28091:EL309_RS01805
uniprot id: A0A3S5B2L4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

28091:EL309 RS01060
gene id: 28091:EL309_RS01060
uniprot id: A0A3S4ZIU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

28091:EL309 RS01610
gene id: 28091:EL309_RS01610
uniprot id: A0A448VIU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

28091:EL309 RS01570
gene id: 28091:EL309_RS01570
uniprot id: A0A3S5F9I2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

28091:EL309 RS04415
gene id: 28091:EL309_RS04415
uniprot id: A0A448VLX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

28091:EL309 RS04095
gene id: 28091:EL309_RS04095
uniprot id: A0A448VLH6
names: Similarity
messages: Belongs to the peptidase M24B family.

28091:EL309 RS10035
gene id: 28091:EL309_RS10035
uniprot id: A0A3S5CB05
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

28091:EL309 RS08535
gene id: 28091:EL309_RS08535
uniprot id: A0A3S4Z5B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

28091:EL309 RS08890
gene id: 28091:EL309_RS08890
uniprot id: A0A3S4ZEB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

28091:EL309 RS06520
gene id: 28091:EL309_RS06520
uniprot id: A0A448VNL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

28091:EL309 RS09865
gene id: 28091:EL309_RS09865
uniprot id: A0A3S5AC33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

28091:EL309 RS07130
gene id: 28091:EL309_RS07130
uniprot id: A0A3S4ZM46
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

28091:EL309 RS00360
gene id: 28091:EL309_RS00360
uniprot id: A0A448VHB1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

28091:EL309 RS06795
gene id: 28091:EL309_RS06795
uniprot id: A0A3S4ZM08
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS07940
gene id: 28091:EL309_RS07940
uniprot id: A0A3S4ZE09
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

28091:EL309 RS07855
gene id: 28091:EL309_RS07855
uniprot id: A0A3S5B5J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

28091:EL309 RS08985
gene id: 28091:EL309_RS08985
uniprot id: A0A3S4ZMP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

28091:EL309 RS04550
gene id: 28091:EL309_RS04550
uniprot id: A0A3S4ZL03
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

28091:EL309 RS05060
gene id: 28091:EL309_RS05060
uniprot id: A0A3S4YRE8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

28091:EL309 RS09635
gene id: 28091:EL309_RS09635
uniprot id: A0A3S4Z5K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Slam family.
messages: Cell outer membrane
messages: Membrane

28091:EL309 RS08230
gene id: 28091:EL309_RS08230
uniprot id: A0A448VPM8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

28091:EL309 RS04640
gene id: 28091:EL309_RS04640
uniprot id: A0A3S4YR51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

28091:EL309 RS00580
gene id: 28091:EL309_RS00580
uniprot id: A0A3S4ZIH4
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

28091:EL309 RS01500
gene id: 28091:EL309_RS01500
uniprot id: A0A448VIR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

28091:EL309 RS04200
gene id: 28091:EL309_RS04200
uniprot id: A0A3S5F9P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

28091:EL309 RS00400
gene id: 28091:EL309_RS00400
uniprot id: A0A3S4ZA77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

28091:EL309 RS10070
gene id: 28091:EL309_RS10070
uniprot id: A0A448VQN4
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

28091:EL309 RS09025
gene id: 28091:EL309_RS09025
uniprot id: A0A448VQ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28091:EL309 RS02860
gene id: 28091:EL309_RS02860
uniprot id: A0A3S5B398
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

28091:EL309 RS08905
gene id: 28091:EL309_RS08905
uniprot id: A0A3S4ZMP1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

28091:EL309 RS09345
gene id: 28091:EL309_RS09345
uniprot id: A0A448VQ78
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS03110
gene id: 28091:EL309_RS03110
uniprot id: A0A448VKE2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

28091:EL309 RS02870
gene id: 28091:EL309_RS02870
uniprot id: A0A3S5C9T4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

28091:EL309 RS10485
gene id: 28091:EL309_RS10485
uniprot id: A0A3S4ZN26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

28091:EL309 RS10055
gene id: 28091:EL309_RS10055
uniprot id: A0A3S4ZAP6
names: Similarity
messages: Belongs to the opacity porin family.

28091:EL309 RS05325
gene id: 28091:EL309_RS05325
uniprot id: A0A3S4ZD60
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS07890
gene id: 28091:EL309_RS07890
uniprot id: A0A448VPM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

28091:EL309 RS07895
gene id: 28091:EL309_RS07895
uniprot id: A0A3S4Z531
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS10040
gene id: 28091:EL309_RS10040
uniprot id: A0A3S5F9W4
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

28091:EL309 RS03955
gene id: 28091:EL309_RS03955
uniprot id: A0A448VLE9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

28091:EL309 RS05130
gene id: 28091:EL309_RS05130
uniprot id: A0A3S5B4L8
names: Similarity
messages: Belongs to the pyruvate kinase family.

28091:EL309 RS07915
gene id: 28091:EL309_RS07915
uniprot id: A0A448VPE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

28091:EL309 RS06570
gene id: 28091:EL309_RS06570
uniprot id: A0A448VNM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

28091:EL309 RS01160
gene id: 28091:EL309_RS01160
uniprot id: A0A448VIC8
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS06230
gene id: 28091:EL309_RS06230
uniprot id: A0A3S5AAV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

28091:EL309 RS05705
gene id: 28091:EL309_RS05705
uniprot id: A0A3S4YRS8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

28091:EL309 RS01330
gene id: 28091:EL309_RS01330
uniprot id: A0A448VIF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

28091:EL309 RS10500
gene id: 28091:EL309_RS10500
uniprot id: A0A3S4Z5U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

28091:EL309 RS09910
gene id: 28091:EL309_RS09910
uniprot id: A0A3S5CB02
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

28091:EL309 RS05660
gene id: 28091:EL309_RS05660
uniprot id: A0A3S5C450
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

28091:EL309 RS08950
gene id: 28091:EL309_RS08950
uniprot id: A0A448VQB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

28091:EL309 RS01940
gene id: 28091:EL309_RS01940
uniprot id: A0A448VJ88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

28091:EL309 RS01095
gene id: 28091:EL309_RS01095
uniprot id: A0A3S4ZAN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

28091:EL309 RS00700
gene id: 28091:EL309_RS00700
uniprot id: A0A3S4YNE9
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

28091:EL309 RS06545
gene id: 28091:EL309_RS06545
uniprot id: A0A3S4ZLW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

28091:EL309 RS01860
gene id: 28091:EL309_RS01860
uniprot id: A0A3S5F9I8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

28091:EL309 RS08125
gene id: 28091:EL309_RS08125
uniprot id: A0A3S5F9U5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

28091:EL309 RS03830
gene id: 28091:EL309_RS03830
uniprot id: A0A448VLC7
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS09165
gene id: 28091:EL309_RS09165
uniprot id: A0A448VQ16
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

28091:EL309 RS06775
gene id: 28091:EL309_RS06775
uniprot id: A0A3S5B571
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS07970
gene id: 28091:EL309_RS07970
uniprot id: A0A3S4ZME6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

28091:EL309 RS05910
gene id: 28091:EL309_RS05910
uniprot id: A0A3S4YRV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

28091:EL309 RS01310
gene id: 28091:EL309_RS01310
uniprot id: A0A3S5F9H5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

28091:EL309 RS01635
gene id: 28091:EL309_RS01635
uniprot id: A0A3S5C9G2
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS03680
gene id: 28091:EL309_RS03680
uniprot id: A0A3S4YQI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

28091:EL309 RS04965
gene id: 28091:EL309_RS04965
uniprot id: A0A3S5CAA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

28091:EL309 RS00585
gene id: 28091:EL309_RS00585
uniprot id: A0A448VHL7
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

28091:EL309 RS06875
gene id: 28091:EL309_RS06875
uniprot id: A0A3S4Z4R2
names: Similarity
messages: Belongs to the HIBADH-related family.

28091:EL309 RS06170
gene id: 28091:EL309_RS06170
uniprot id: A0A448VNG1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family. EfeB subfamily.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

28091:EL309 RS05205
gene id: 28091:EL309_RS05205
uniprot id: A0A448VMU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

28091:EL309 RS09950
gene id: 28091:EL309_RS09950
uniprot id: A0A3S5AC43
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

28091:EL309 RS00320
gene id: 28091:EL309_RS00320
uniprot id: A0A448VH91
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS04120
gene id: 28091:EL309_RS04120
uniprot id: A0A3S5A9H9
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

28091:EL309 RS05405
gene id: 28091:EL309_RS05405
uniprot id: A0A3S5C432
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

28091:EL309 RS04170
gene id: 28091:EL309_RS04170
uniprot id: A0A448VLP8
names: Similarity
messages: Belongs to the TrpC family.

28091:EL309 RS02745
gene id: 28091:EL309_RS02745
uniprot id: A0A3S5F9K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

28091:EL309 RS10595
gene id: 28091:EL309_RS10595
uniprot id: A0A3S4Z5V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

28091:EL309 RS03815
gene id: 28091:EL309_RS03815
uniprot id: A0A3S5A9B1
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

28091:EL309 RS06280
gene id: 28091:EL309_RS06280
uniprot id: A0A448VNK4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

28091:EL309 RS08555
gene id: 28091:EL309_RS08555
uniprot id: A0A448VPT5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

28091:EL309 RS05915
gene id: 28091:EL309_RS05915
uniprot id: A0A448VND1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

28091:EL309 RS05095
gene id: 28091:EL309_RS05095
uniprot id: A0A3S4ZD17
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

28091:EL309 RS06265
gene id: 28091:EL309_RS06265
uniprot id: A0A448VNJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

28091:EL309 RS08565
gene id: 28091:EL309_RS08565
uniprot id: A0A448VPS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

28091:EL309 RS04660
gene id: 28091:EL309_RS04660
uniprot id: A0A3S4Z8M2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

28091:EL309 RS08105
gene id: 28091:EL309_RS08105
uniprot id: A0A448VPV9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

28091:EL309 RS06390
gene id: 28091:EL309_RS06390
uniprot id: A0A3S4ZLV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

28091:EL309 RS08270
gene id: 28091:EL309_RS08270
uniprot id: A0A3S4ZMI4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

28091:EL309 RS06735
gene id: 28091:EL309_RS06735
uniprot id: A0A3S4Z4P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

28091:EL309 RS07275
gene id: 28091:EL309_RS07275
uniprot id: A0A3S4Z9U2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

28091:EL309 RS09715
gene id: 28091:EL309_RS09715
uniprot id: A0A448VQF3
names: Similarity
messages: Belongs to the threonine synthase family.

28091:EL309 RS04555
gene id: 28091:EL309_RS04555
uniprot id: A0A448VM12
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

28091:EL309 RS07510
gene id: 28091:EL309_RS07510
uniprot id: A0A448VP54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

28091:EL309 RS04065
gene id: 28091:EL309_RS04065
uniprot id: A0A448VLK6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

28091:EL309 RS09000
gene id: 28091:EL309_RS09000
uniprot id: A0A448VQC7
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS07610
gene id: 28091:EL309_RS07610
uniprot id: A0A3S5F9T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

28091:EL309 RS01865
gene id: 28091:EL309_RS01865
uniprot id: A0A3S4Z262
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

28091:EL309 RS03705
gene id: 28091:EL309_RS03705
uniprot id: A0A448VL07
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

28091:EL309 RS02965
gene id: 28091:EL309_RS02965
uniprot id: A0A3S4ZBW4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

28091:EL309 RS04995
gene id: 28091:EL309_RS04995
uniprot id: A0A3S5B4H7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

28091:EL309 RS06160
gene id: 28091:EL309_RS06160
uniprot id: A0A448VNJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

28091:EL309 RS00620
gene id: 28091:EL309_RS00620
uniprot id: A0A448VHM2
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

28091:EL309 RS02305
gene id: 28091:EL309_RS02305
uniprot id: A0A448VJL7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

28091:EL309 RS00340
gene id: 28091:EL309_RS00340
uniprot id: A0A448VHA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

28091:EL309 RS05305
gene id: 28091:EL309_RS05305
uniprot id: A0A3S4Z475
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

28091:EL309 RS00290
gene id: 28091:EL309_RS00290
uniprot id: A0A448VH86
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS04445
gene id: 28091:EL309_RS04445
uniprot id: A0A3S5B460
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

28091:EL309 RS10565
gene id: 28091:EL309_RS10565
uniprot id: A0A448VR74
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

28091:EL309 RS07475
gene id: 28091:EL309_RS07475
uniprot id: A0A3S4ZDV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

28091:EL309 RS03990
gene id: 28091:EL309_RS03990
uniprot id: A0A448VLD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

28091:EL309 RS04880
gene id: 28091:EL309_RS04880
uniprot id: A0A3S5C3X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

28091:EL309 RS06605
gene id: 28091:EL309_RS06605
uniprot id: A0A448VNY3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

28091:EL309 RS00445
gene id: 28091:EL309_RS00445
uniprot id: A0A448VHG1
names: Similarity
messages: Belongs to the peptidase C40 family.

28091:EL309 RS08580
gene id: 28091:EL309_RS08580
uniprot id: A0A3S5ABP8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

28091:EL309 RS08310
gene id: 28091:EL309_RS08310
uniprot id: A0A3S4ZA86
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

28091:EL309 RS04975
gene id: 28091:EL309_RS04975
uniprot id: A0A448VMN2
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

28091:EL309 RS07285
gene id: 28091:EL309_RS07285
uniprot id: A0A448VPF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

28091:EL309 RS07225
gene id: 28091:EL309_RS07225
uniprot id: A0A3S4ZM58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

28091:EL309 RS01035
gene id: 28091:EL309_RS01035
uniprot id: A0A3S4YNP0
names: Similarity
messages: Belongs to the citrate synthase family.

28091:EL309 RS06640
gene id: 28091:EL309_RS06640
uniprot id: A0A448VNP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

28091:EL309 RS09235
gene id: 28091:EL309_RS09235
uniprot id: A0A3S4ZEF5
names: Similarity
messages: Belongs to the NAD synthetase family.

28091:EL309 RS09360
gene id: 28091:EL309_RS09360
uniprot id: A0A3S5ABY1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

28091:EL309 RS09220
gene id: 28091:EL309_RS09220
uniprot id: A0A448VQ38
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS06070
gene id: 28091:EL309_RS06070
uniprot id: A0A448VND8
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

28091:EL309 RS01855
gene id: 28091:EL309_RS01855
uniprot id: A0A448VJ35
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

28091:EL309 RS03840
gene id: 28091:EL309_RS03840
uniprot id: A0A3S4ZKK4
names: Similarity
messages: Belongs to the peptidase C40 family.

28091:EL309 RS04545
gene id: 28091:EL309_RS04545
uniprot id: A0A3S5B483
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

28091:EL309 RS03220
gene id: 28091:EL309_RS03220
uniprot id: A0A3S4ZK83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

28091:EL309 RS05375
gene id: 28091:EL309_RS05375
uniprot id: A0A3S5B4Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28091:EL309 RS06355
gene id: 28091:EL309_RS06355
uniprot id: A0A3S5B524
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

28091:EL309 RS07645
gene id: 28091:EL309_RS07645
uniprot id: A0A448VP93
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

28091:EL309 RS06740
gene id: 28091:EL309_RS06740
uniprot id: A0A448VNT9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

28091:EL309 RS04185
gene id: 28091:EL309_RS04185
uniprot id: A0A3S4ZCJ8
names: Similarity
messages: Belongs to the UPF0307 family.

28091:EL309 RS03325
gene id: 28091:EL309_RS03325
uniprot id: A0A448VKU3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

28091:EL309 RS06320
gene id: 28091:EL309_RS06320
uniprot id: A0A448VNK7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

28091:EL309 RS07265
gene id: 28091:EL309_RS07265
uniprot id: A0A448VP59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

28091:EL309 RS09585
gene id: 28091:EL309_RS09585
uniprot id: A0A3S5C331
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

28091:EL309 RS01155
gene id: 28091:EL309_RS01155
uniprot id: A0A448VI95
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

28091:EL309 RS04655
gene id: 28091:EL309_RS04655
uniprot id: A0A3S4Z3U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

28091:EL309 RS07515
gene id: 28091:EL309_RS07515
uniprot id: A0A3S4YSC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

28091:EL309 RS06615
gene id: 28091:EL309_RS06615
uniprot id: A0A448VP26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

28091:EL309 RS03375
gene id: 28091:EL309_RS03375
uniprot id: A0A3S5C3K1
names: Similarity
messages: Belongs to the citrate synthase family.

28091:EL309 RS10510
gene id: 28091:EL309_RS10510
uniprot id: A0A448VR16
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS10515
gene id: 28091:EL309_RS10515
uniprot id: A0A448VR61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

28091:EL309 RS09725
gene id: 28091:EL309_RS09725
uniprot id: A0A3S5CAZ3
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

28091:EL309 RS06095
gene id: 28091:EL309_RS06095
uniprot id: A0A448VNS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

28091:EL309 RS05840
gene id: 28091:EL309_RS05840
uniprot id: A0A3S4Z4F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

28091:EL309 RS07250
gene id: 28091:EL309_RS07250
uniprot id: A0A448VP43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

28091:EL309 RS06590
gene id: 28091:EL309_RS06590
uniprot id: A0A3S5AAZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

28091:EL309 RS08175
gene id: 28091:EL309_RS08175
uniprot id: A0A3S4YSK7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

28091:EL309 RS07400
gene id: 28091:EL309_RS07400
uniprot id: A0A3S4ZDU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

28091:EL309 RS06700
gene id: 28091:EL309_RS06700
uniprot id: A0A3S4YS28
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

28091:EL309 RS00805
gene id: 28091:EL309_RS00805
uniprot id: A0A448VHV8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

28091:EL309 RS03935
gene id: 28091:EL309_RS03935
uniprot id: A0A3S5F9N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

28091:EL309 RS01030
gene id: 28091:EL309_RS01030
uniprot id: A0A3S5C2Y7
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

28091:EL309 RS01325
gene id: 28091:EL309_RS01325
uniprot id: A0A448VIH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

28091:EL309 RS10255
gene id: 28091:EL309_RS10255
uniprot id: A0A448VR09
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

28091:EL309 RS01525
gene id: 28091:EL309_RS01525
uniprot id: A0A3S5B2D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

28091:EL309 RS07040
gene id: 28091:EL309_RS07040
uniprot id: A0A3S4ZM39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

28091:EL309 RS03270
gene id: 28091:EL309_RS03270
uniprot id: A0A448VKN3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

28091:EL309 RS03920
gene id: 28091:EL309_RS03920
uniprot id: A0A448VLD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

28091:EL309 RS01770
gene id: 28091:EL309_RS01770
uniprot id: A0A3S4ZJB2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

28091:EL309 RS04850
gene id: 28091:EL309_RS04850
uniprot id: A0A3S4YR91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

28091:EL309 RS09470
gene id: 28091:EL309_RS09470
uniprot id: A0A448VQG8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

28091:EL309 RS07780
gene id: 28091:EL309_RS07780
uniprot id: A0A3S5F9U1
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

28091:EL309 RS00605
gene id: 28091:EL309_RS00605
uniprot id: A0A3S4YNC1
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

28091:EL309 RS07005
gene id: 28091:EL309_RS07005
uniprot id: A0A3S5C4A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

28091:EL309 RS07770
gene id: 28091:EL309_RS07770
uniprot id: A0A3S5CAR6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

28091:EL309 RS09460
gene id: 28091:EL309_RS09460
uniprot id: A0A3S5ABZ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS05160
gene id: 28091:EL309_RS05160
uniprot id: A0A3S4Z900
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

28091:EL309 RS05410
gene id: 28091:EL309_RS05410
uniprot id: A0A3S5AAI6
names: Similarity
messages: Belongs to the peptidase S51 family.

28091:EL309 RS07220
gene id: 28091:EL309_RS07220
uniprot id: A0A3S4YS91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

28091:EL309 RS06665
gene id: 28091:EL309_RS06665
uniprot id: A0A448VP39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

28091:EL309 RS00645
gene id: 28091:EL309_RS00645
uniprot id: A0A3S4ZAC1
names: Similarity
messages: Belongs to the DEAD box helicase family.

28091:EL309 RS04295
gene id: 28091:EL309_RS04295
uniprot id: A0A448VLT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

28091:EL309 RS10460
gene id: 28091:EL309_RS10460
uniprot id: A0A448VR03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

28091:EL309 RS07210
gene id: 28091:EL309_RS07210
uniprot id: A0A448VP08
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

28091:EL309 RS08135
gene id: 28091:EL309_RS08135
uniprot id: A0A3S4ZA54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

28091:EL309 RS00990
gene id: 28091:EL309_RS00990
uniprot id: A0A448VI45
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

28091:EL309 RS04650
gene id: 28091:EL309_RS04650
uniprot id: A0A3S5F9P9
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS01085
gene id: 28091:EL309_RS01085
uniprot id: A0A448VI99
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

28091:EL309 RS09605
gene id: 28091:EL309_RS09605
uniprot id: A0A3S5CAY9
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

28091:EL309 RS01900
gene id: 28091:EL309_RS01900
uniprot id: A0A3S5F9I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Membrane

28091:EL309 RS07310
gene id: 28091:EL309_RS07310
uniprot id: A0A3S5B5E0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

28091:EL309 RS04455
gene id: 28091:EL309_RS04455
uniprot id: A0A448VLX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

28091:EL309 RS07675
gene id: 28091:EL309_RS07675
uniprot id: A0A448VPH7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

28091:EL309 RS07680
gene id: 28091:EL309_RS07680
uniprot id: A0A448VPD5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.

28091:EL309 RS05140
gene id: 28091:EL309_RS05140
uniprot id: A0A3S4ZLC7
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

28091:EL309 RS00975
gene id: 28091:EL309_RS00975
uniprot id: A0A3S5C988
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

28091:EL309 RS10580
gene id: 28091:EL309_RS10580
uniprot id: A0A3S5CB32
names: Similarity
messages: Belongs to the GSP E family.

28091:EL309 RS05110
gene id: 28091:EL309_RS05110
uniprot id: A0A3S4ZLB8
names: Similarity
messages: Belongs to the SlyX family.

28091:EL309 RS05225
gene id: 28091:EL309_RS05225
uniprot id: A0A448VMX8
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

28091:EL309 RS05080
gene id: 28091:EL309_RS05080
uniprot id: A0A3S5C3Z8
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

28091:EL309 RS06685
gene id: 28091:EL309_RS06685
uniprot id: A0A3S4ZDL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

28091:EL309 RS07790
gene id: 28091:EL309_RS07790
uniprot id: A0A3S4Z515
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

28091:EL309 RS04210
gene id: 28091:EL309_RS04210
uniprot id: A0A448VLV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

28091:EL309 RS05755
gene id: 28091:EL309_RS05755
uniprot id: A0A3S4Z4E9
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

28091:EL309 RS06975
gene id: 28091:EL309_RS06975
uniprot id: A0A3S4Z4S1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

28091:EL309 RS04050
gene id: 28091:EL309_RS04050
uniprot id: A0A448VLK9
names: Similarity
messages: Belongs to the YkuD family.

28091:EL309 RS05780
gene id: 28091:EL309_RS05780
uniprot id: A0A3S5AAQ4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

28091:EL309 RS00380
gene id: 28091:EL309_RS00380
uniprot id: A0A3S4Z5R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

28091:EL309 RS06225
gene id: 28091:EL309_RS06225
uniprot id: A0A448VNJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

28091:EL309 RS02670
gene id: 28091:EL309_RS02670
uniprot id: A0A3S5C9R7
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

28091:EL309 RS02090
gene id: 28091:EL309_RS02090
uniprot id: A0A3S5F9J3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

28091:EL309 RS00450
gene id: 28091:EL309_RS00450
uniprot id: A0A3S5A6T0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

28091:EL309 RS06065
gene id: 28091:EL309_RS06065
uniprot id: A0A3S4Z4H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

28091:EL309 RS09255
gene id: 28091:EL309_RS09255
uniprot id: A0A448VQ96
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

28091:EL309 RS00335
gene id: 28091:EL309_RS00335
uniprot id: A0A448VHA0
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

28091:EL309 RS08490
gene id: 28091:EL309_RS08490
uniprot id: A0A3S5B5T9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

28091:EL309 RS08170
gene id: 28091:EL309_RS08170
uniprot id: A0A3S5B5P4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS04060
gene id: 28091:EL309_RS04060
uniprot id: A0A3S4Z883
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

28091:EL309 RS02170
gene id: 28091:EL309_RS02170
uniprot id: A0A448VJH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

28091:EL309 RS07470
gene id: 28091:EL309_RS07470
uniprot id: A0A3S5ABA1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

28091:EL309 RS06205
gene id: 28091:EL309_RS06205
uniprot id: A0A448VNI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

28091:EL309 RS07110
gene id: 28091:EL309_RS07110
uniprot id: A0A448VP24
names: Similarity
messages: Belongs to the peptidase U62 family.

28091:EL309 RS02070
gene id: 28091:EL309_RS02070
uniprot id: A0A3S5C394
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS00285
gene id: 28091:EL309_RS00285
uniprot id: A0A3S5C920
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

28091:EL309 RS09500
gene id: 28091:EL309_RS09500
uniprot id: A0A448VQA2
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Homodimer.

28091:EL309 RS10195
gene id: 28091:EL309_RS10195
uniprot id: A0A3S4ZN02
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

28091:EL309 RS08640
gene id: 28091:EL309_RS08640
uniprot id: A0A3S5F9V0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

28091:EL309 RS08045
gene id: 28091:EL309_RS08045
uniprot id: A0A3S4YSI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

28091:EL309 RS01145
gene id: 28091:EL309_RS01145
uniprot id: A0A3S5C9B0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

28091:EL309 RS01235
gene id: 28091:EL309_RS01235
uniprot id: A0A3S5A7E9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

28091:EL309 RS07765
gene id: 28091:EL309_RS07765
uniprot id: A0A3S4ZMC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

28091:EL309 RS08635
gene id: 28091:EL309_RS08635
uniprot id: A0A3S5CAV4
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

28091:EL309 RS04725
gene id: 28091:EL309_RS04725
uniprot id: A0A448VMB5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

28091:EL309 RS07050
gene id: 28091:EL309_RS07050
uniprot id: A0A448VP71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

28091:EL309 RS08390
gene id: 28091:EL309_RS08390
uniprot id: A0A3S5F9U8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

28091:EL309 RS10185
gene id: 28091:EL309_RS10185
uniprot id: A0A3S5B695
names: Cofactor
names: Similarity
messages: Belongs to the Nudix hydrolase family.
messages: Binds 1 Mg(2+) ion per subunit.

28091:EL309 RS03395
gene id: 28091:EL309_RS03395
uniprot id: A0A3S4ZKB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

28091:EL309 RS00345
gene id: 28091:EL309_RS00345
uniprot id: A0A448VHA3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

28091:EL309 RS01050
gene id: 28091:EL309_RS01050
uniprot id: A0A448VI80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

28091:EL309 RS09615
gene id: 28091:EL309_RS09615
uniprot id: A0A448VQD0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

28091:EL309 RS05115
gene id: 28091:EL309_RS05115
uniprot id: A0A3S5F9Q9
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS07630
gene id: 28091:EL309_RS07630
uniprot id: A0A3S5C4D4
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

28091:EL309 RS04890
gene id: 28091:EL309_RS04890
uniprot id: A0A3S4ZCW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

28091:EL309 RS04805
gene id: 28091:EL309_RS04805
uniprot id: A0A3S5CA96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

28091:EL309 RS06215
gene id: 28091:EL309_RS06215
uniprot id: A0A448VNI0
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

28091:EL309 RS03155
gene id: 28091:EL309_RS03155
uniprot id: A0A448VKL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

28091:EL309 RS09835
gene id: 28091:EL309_RS09835
uniprot id: A0A3S4Z5N4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

28091:EL309 RS08595
gene id: 28091:EL309_RS08595
uniprot id: A0A448VPR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

28091:EL309 RS04885
gene id: 28091:EL309_RS04885
uniprot id: A0A3S5AA22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

28091:EL309 RS07295
gene id: 28091:EL309_RS07295
uniprot id: A0A3S5AB79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

28091:EL309 RS01665
gene id: 28091:EL309_RS01665
uniprot id: A0A3S5B2H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

28091:EL309 RS07735
gene id: 28091:EL309_RS07735
uniprot id: A0A3S4ZDY8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

28091:EL309 RS05175
gene id: 28091:EL309_RS05175
uniprot id: A0A3S4ZLD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

28091:EL309 RS10600
gene id: 28091:EL309_RS10600
uniprot id: A0A3S4ZAV9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

28091:EL309 RS08225
gene id: 28091:EL309_RS08225
uniprot id: A0A3S4ZA67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

28091:EL309 RS10130
gene id: 28091:EL309_RS10130
uniprot id: A0A448VQQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

28091:EL309 RS10030
gene id: 28091:EL309_RS10030
uniprot id: A0A448VQM0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

28091:EL309 RS02625
gene id: 28091:EL309_RS02625
uniprot id: A0A448VJX8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

28091:EL309 RS01070
gene id: 28091:EL309_RS01070
uniprot id: A0A3S4Z1L1
names: Similarity
messages: Belongs to the glutamate synthase family.

28091:EL309 RS05215
gene id: 28091:EL309_RS05215
uniprot id: A0A448VMY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

28091:EL309 RS10250
gene id: 28091:EL309_RS10250
uniprot id: A0A448VQV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

28091:EL309 RS01930
gene id: 28091:EL309_RS01930
uniprot id: A0A448VJ68
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

28091:EL309 RS00375
gene id: 28091:EL309_RS00375
uniprot id: A0A3S4Z168
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

28091:EL309 RS09020
gene id: 28091:EL309_RS09020
uniprot id: A0A3S5F9V4
names: Similarity
messages: Belongs to the UPF0246 family.

28091:EL309 RS05620
gene id: 28091:EL309_RS05620
uniprot id: A0A448VNB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

28091:EL309 RS05740
gene id: 28091:EL309_RS05740
uniprot id: A0A3S4ZLN4
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

28091:EL309 RS07345
gene id: 28091:EL309_RS07345
uniprot id: A0A448VP27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS07245
gene id: 28091:EL309_RS07245
uniprot id: A0A3S5F9T5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

28091:EL309 RS09105
gene id: 28091:EL309_RS09105
uniprot id: A0A3S5CAX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

28091:EL309 RS10375
gene id: 28091:EL309_RS10375
uniprot id: A0A3S4YT74
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

28091:EL309 RS01630
gene id: 28091:EL309_RS01630
uniprot id: A0A448VIV0
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS08620
gene id: 28091:EL309_RS08620
uniprot id: A0A3S4YSQ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

28091:EL309 RS07985
gene id: 28091:EL309_RS07985
uniprot id: A0A448VPF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

28091:EL309 RS02890
gene id: 28091:EL309_RS02890
uniprot id: A0A448VKB3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

28091:EL309 RS09320
gene id: 28091:EL309_RS09320
uniprot id: A0A3S4Z5I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

28091:EL309 RS04625
gene id: 28091:EL309_RS04625
uniprot id: A0A448VMD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

28091:EL309 RS09100
gene id: 28091:EL309_RS09100
uniprot id: A0A3S4ZMQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

28091:EL309 RS07725
gene id: 28091:EL309_RS07725
uniprot id: A0A3S5C4E0
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS07425
gene id: 28091:EL309_RS07425
uniprot id: A0A3S5CAP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

28091:EL309 RS04090
gene id: 28091:EL309_RS04090
uniprot id: A0A448VLL6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

28091:EL309 RS07530
gene id: 28091:EL309_RS07530
uniprot id: A0A448VPB1
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS06995
gene id: 28091:EL309_RS06995
uniprot id: A0A3S4Z9Q7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

28091:EL309 RS02820
gene id: 28091:EL309_RS02820
uniprot id: A0A448VK79
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

28091:EL309 RS07125
gene id: 28091:EL309_RS07125
uniprot id: A0A3S4YS83
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

28091:EL309 RS09610
gene id: 28091:EL309_RS09610
uniprot id: A0A448VQC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

28091:EL309 RS05830
gene id: 28091:EL309_RS05830
uniprot id: A0A448VNM3
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

28091:EL309 RS03065
gene id: 28091:EL309_RS03065
uniprot id: A0A3S4Z7L6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

28091:EL309 RS07560
gene id: 28091:EL309_RS07560
uniprot id: A0A3S5C4D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

28091:EL309 RS06970
gene id: 28091:EL309_RS06970
uniprot id: A0A448VNU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

28091:EL309 RS01010
gene id: 28091:EL309_RS01010
uniprot id: A0A3S4ZAK3
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

28091:EL309 RS09875
gene id: 28091:EL309_RS09875
uniprot id: A0A3S4ZEL4
names: Similarity
messages: Belongs to the HSP15 family.

28091:EL309 RS02005
gene id: 28091:EL309_RS02005
uniprot id: A0A448VJA5
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

28091:EL309 RS04480
gene id: 28091:EL309_RS04480
uniprot id: A0A3S5C3U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

28091:EL309 RS09870
gene id: 28091:EL309_RS09870
uniprot id: A0A448VQG7
names: Function
names: Similarity
messages: Belongs to the ClpA/ClpB family.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

28091:EL309 RS06420
gene id: 28091:EL309_RS06420
uniprot id: A0A448VNN1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

28091:EL309 RS06240
gene id: 28091:EL309_RS06240
uniprot id: A0A3S4ZDH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

28091:EL309 RS07140
gene id: 28091:EL309_RS07140
uniprot id: A0A3S5F9T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

28091:EL309 RS02180
gene id: 28091:EL309_RS02180
uniprot id: A0A3S5A866
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

28091:EL309 RS01530
gene id: 28091:EL309_RS01530
uniprot id: A0A448VIQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

28091:EL309 RS06125
gene id: 28091:EL309_RS06125
uniprot id: A0A448VNH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

28091:EL309 RS10370
gene id: 28091:EL309_RS10370
uniprot id: A0A448VQQ5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

28091:EL309 RS10020
gene id: 28091:EL309_RS10020
uniprot id: A0A448VQM2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

28091:EL309 RS08550
gene id: 28091:EL309_RS08550
uniprot id: A0A3S4ZAA3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

28091:EL309 RS03300
gene id: 28091:EL309_RS03300
uniprot id: A0A3S5F9M1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

28091:EL309 RS04055
gene id: 28091:EL309_RS04055
uniprot id: A0A448VLI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

28091:EL309 RS06565
gene id: 28091:EL309_RS06565
uniprot id: A0A448VP14
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

28091:EL309 RS07620
gene id: 28091:EL309_RS07620
uniprot id: A0A3S4Z4Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
messages: Periplasm

28091:EL309 RS04670
gene id: 28091:EL309_RS04670
uniprot id: A0A3S5A9X7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS06245
gene id: 28091:EL309_RS06245
uniprot id: A0A3S5B509
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS07930
gene id: 28091:EL309_RS07930
uniprot id: A0A3S5C4E7
names: Similarity
messages: Belongs to the YicC/YloC family.

28091:EL309 RS02480
gene id: 28091:EL309_RS02480
uniprot id: A0A448VJT7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

28091:EL309 RS09465
gene id: 28091:EL309_RS09465
uniprot id: A0A448VQB2
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

28091:EL309 RS05710
gene id: 28091:EL309_RS05710
uniprot id: A0A448VN85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

28091:EL309 RS03900
gene id: 28091:EL309_RS03900
uniprot id: A0A3S4ZCD8
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

28091:EL309 RS00515
gene id: 28091:EL309_RS00515
uniprot id: A0A3S5B1P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

28091:EL309 RS07990
gene id: 28091:EL309_RS07990
uniprot id: A0A3S4Z541
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Homodimer.

28091:EL309 RS10430
gene id: 28091:EL309_RS10430
uniprot id: A0A3S5C4M5
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

28091:EL309 RS03000
gene id: 28091:EL309_RS03000
uniprot id: A0A448VKE5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Binds 1 Cu(+) ion.
messages: Cell outer membrane
messages: Homotrimer.
messages: Membrane

28091:EL309 RS07815
gene id: 28091:EL309_RS07815
uniprot id: A0A448VPC0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

28091:EL309 RS02140
gene id: 28091:EL309_RS02140
uniprot id: A0A448VJG0
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

28091:EL309 RS09455
gene id: 28091:EL309_RS09455
uniprot id: A0A3S5C4K2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

28091:EL309 RS02045
gene id: 28091:EL309_RS02045
uniprot id: A0A448VJB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS07045
gene id: 28091:EL309_RS07045
uniprot id: A0A3S5CAN0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

28091:EL309 RS09420
gene id: 28091:EL309_RS09420
uniprot id: A0A3S5CAY3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS06985
gene id: 28091:EL309_RS06985
uniprot id: A0A448VP07
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

28091:EL309 RS00415
gene id: 28091:EL309_RS00415
uniprot id: A0A3S5C929
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

28091:EL309 RS04155
gene id: 28091:EL309_RS04155
uniprot id: A0A448VLK5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

28091:EL309 RS04750
gene id: 28091:EL309_RS04750
uniprot id: A0A3S4ZCU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

28091:EL309 RS08945
gene id: 28091:EL309_RS08945
uniprot id: A0A448VQ34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

28091:EL309 RS09305
gene id: 28091:EL309_RS09305
uniprot id: A0A3S5F9V7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

28091:EL309 RS03120
gene id: 28091:EL309_RS03120
uniprot id: A0A448VKJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

28091:EL309 RS06715
gene id: 28091:EL309_RS06715
uniprot id: A0A3S5CAL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

28091:EL309 RS07185
gene id: 28091:EL309_RS07185
uniprot id: A0A3S5AB70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

28091:EL309 RS02825
gene id: 28091:EL309_RS02825
uniprot id: A0A3S4ZK00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

28091:EL309 RS08325
gene id: 28091:EL309_RS08325
uniprot id: A0A448VQ01
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

28091:EL309 RS08360
gene id: 28091:EL309_RS08360
uniprot id: A0A448VPM7
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS07920
gene id: 28091:EL309_RS07920
uniprot id: A0A448VPG6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

28091:EL309 RS09655
gene id: 28091:EL309_RS09655
uniprot id: A0A3S4ZAK7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

28091:EL309 RS06505
gene id: 28091:EL309_RS06505
uniprot id: A0A448VNW0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

28091:EL309 RS05250
gene id: 28091:EL309_RS05250
uniprot id: A0A3S4Z922
names: Similarity
names: Subunit
messages: Belongs to the N-Me-Phe pilin family.
messages: The pili are polar flexible filaments of about 5.4 nanometers diameter and 2.5 micrometers average length; they consist of only a single polypeptide chain arranged in a helical configuration of five subunits per turn in the assembled pilus.

28091:EL309 RS04130
gene id: 28091:EL309_RS04130
uniprot id: A0A3S5B3Y9
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS07450
gene id: 28091:EL309_RS07450
uniprot id: A0A3S4Z4X3
names: Similarity
messages: Belongs to the PhoH family.

28091:EL309 RS06610
gene id: 28091:EL309_RS06610
uniprot id: A0A3S5B547
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

28091:EL309 RS10225
gene id: 28091:EL309_RS10225
uniprot id: A0A3S4ZAR7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

28091:EL309 RS05520
gene id: 28091:EL309_RS05520
uniprot id: A0A3S4ZD92
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

28091:EL309 RS00950
gene id: 28091:EL309_RS00950
uniprot id: A0A3S4ZAJ3
names: Similarity
messages: Belongs to the UPF0758 family.

28091:EL309 RS03965
gene id: 28091:EL309_RS03965
uniprot id: A0A448VLC2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

28091:EL309 RS09985
gene id: 28091:EL309_RS09985
uniprot id: A0A448VQM6
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

28091:EL309 RS02785
gene id: 28091:EL309_RS02785
uniprot id: A0A448VK45
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

28091:EL309 RS00960
gene id: 28091:EL309_RS00960
uniprot id: A0A448VI19
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

28091:EL309 RS06345
gene id: 28091:EL309_RS06345
uniprot id: A0A3S5C477
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

28091:EL309 RS01535
gene id: 28091:EL309_RS01535
uniprot id: A0A3S5C9F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

28091:EL309 RS00370
gene id: 28091:EL309_RS00370
uniprot id: A0A448VHB6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

28091:EL309 RS00245
gene id: 28091:EL309_RS00245
uniprot id: A0A3S5F9F2
names: Similarity
messages: Belongs to the pirin family.

28091:EL309 RS04630
gene id: 28091:EL309_RS04630
uniprot id: A0A448VM70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

28091:EL309 RS08300
gene id: 28091:EL309_RS08300
uniprot id: A0A448VPL4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

28091:EL309 RS07730
gene id: 28091:EL309_RS07730
uniprot id: A0A3S5ABE7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

28091:EL309 RS03915
gene id: 28091:EL309_RS03915
uniprot id: A0A448VLE3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28091:EL309 RS03410
gene id: 28091:EL309_RS03410
uniprot id: A0A3S4Z353
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS10160
gene id: 28091:EL309_RS10160
uniprot id: A0A3S4ZAQ7
names: Similarity
messages: Belongs to the CutA family.

28091:EL309 RS04045
gene id: 28091:EL309_RS04045
uniprot id: A0A3S5F9N6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

28091:EL309 RS01640
gene id: 28091:EL309_RS01640
uniprot id: A0A3S4Z209
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

28091:EL309 RS08715
gene id: 28091:EL309_RS08715
uniprot id: A0A448VPV3
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

28091:EL309 RS01110
gene id: 28091:EL309_RS01110
uniprot id: A0A448VIB1
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 copper ion per subunit.
messages: Cell outer membrane
messages: Membrane
messages: Periplasm

28091:EL309 RS06655
gene id: 28091:EL309_RS06655
uniprot id: A0A448VP00
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

28091:EL309 RS10090
gene id: 28091:EL309_RS10090
uniprot id: A0A448VQV1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

28091:EL309 RS01320
gene id: 28091:EL309_RS01320
uniprot id: A0A448VIH6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

28091:EL309 RS08520
gene id: 28091:EL309_RS08520
uniprot id: A0A3S5F9U9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

28091:EL309 RS07255
gene id: 28091:EL309_RS07255
uniprot id: A0A3S4Z4V4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS03050
gene id: 28091:EL309_RS03050
uniprot id: A0A3S5C9U8
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

28091:EL309 RS07655
gene id: 28091:EL309_RS07655
uniprot id: A0A3S4ZDX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

28091:EL309 RS10265
gene id: 28091:EL309_RS10265
uniprot id: A0A3S5B6A4
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

28091:EL309 RS10555
gene id: 28091:EL309_RS10555
uniprot id: A0A3S4YT95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

28091:EL309 RS04615
gene id: 28091:EL309_RS04615
uniprot id: A0A3S5CA79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

28091:EL309 RS00935
gene id: 28091:EL309_RS00935
uniprot id: A0A3S5F9G6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

28091:EL309 RS07700
gene id: 28091:EL309_RS07700
uniprot id: A0A3S4ZMB6
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

28091:EL309 RS09505
gene id: 28091:EL309_RS09505
uniprot id: A0A3S4ZMT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

28091:EL309 RS03335
gene id: 28091:EL309_RS03335
uniprot id: A0A3S5A8Y8
names: Similarity
messages: Belongs to the aspartokinase family.

28091:EL309 RS04690
gene id: 28091:EL309_RS04690
uniprot id: A0A448VM91
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

28091:EL309 RS08255
gene id: 28091:EL309_RS08255
uniprot id: A0A3S4YSM2
names: PTM
messages: Binds 1 heme group per subunit.

28091:EL309 RS05605
gene id: 28091:EL309_RS05605
uniprot id: A0A3S4ZDA2
names: Similarity
messages: Belongs to the VapB family.

28091:EL309 RS01475
gene id: 28091:EL309_RS01475
uniprot id: A0A448VIP8
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS08005
gene id: 28091:EL309_RS08005
uniprot id: A0A3S4ZA30
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

28091:EL309 RS03425
gene id: 28091:EL309_RS03425
uniprot id: A0A3S5A916
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

28091:EL309 RS04190
gene id: 28091:EL309_RS04190
uniprot id: A0A3S4YQV4
names: Similarity
messages: Belongs to the peptidase U62 family.

28091:EL309 RS00915
gene id: 28091:EL309_RS00915
uniprot id: A0A3S4ZAI1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS04740
gene id: 28091:EL309_RS04740
uniprot id: A0A448VMA1
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

28091:EL309 RS06255
gene id: 28091:EL309_RS06255
uniprot id: A0A448VNK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

28091:EL309 RS01495
gene id: 28091:EL309_RS01495
uniprot id: A0A3S5A7M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

28091:EL309 RS04795
gene id: 28091:EL309_RS04795
uniprot id: A0A3S5B4D8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

28091:EL309 RS01810
gene id: 28091:EL309_RS01810
uniprot id: A0A448VJ21
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

28091:EL309 RS10305
gene id: 28091:EL309_RS10305
uniprot id: A0A3S5F9W7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

28091:EL309 RS05675
gene id: 28091:EL309_RS05675
uniprot id: A0A448VNA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

28091:EL309 RS02950
gene id: 28091:EL309_RS02950
uniprot id: A0A3S4Z2V4
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

28091:EL309 RS00835
gene id: 28091:EL309_RS00835
uniprot id: A0A448VHV9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

28091:EL309 RS08260
gene id: 28091:EL309_RS08260
uniprot id: A0A448VPP3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

28091:EL309 RS08850
gene id: 28091:EL309_RS08850
uniprot id: A0A3S4Z5D5
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

28091:EL309 RS01020
gene id: 28091:EL309_RS01020
uniprot id: A0A3S5C992
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

28091:EL309 RS04465
gene id: 28091:EL309_RS04465
uniprot id: A0A448VLZ6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

28091:EL309 RS06055
gene id: 28091:EL309_RS06055
uniprot id: A0A3S5F9S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

28091:EL309 RS01345
gene id: 28091:EL309_RS01345
uniprot id: A0A448VII9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

28091:EL309 RS05285
gene id: 28091:EL309_RS05285
uniprot id: A0A3S4ZD48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

28091:EL309 RS02105
gene id: 28091:EL309_RS02105
uniprot id: A0A448VJE3
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

28091:EL309 RS02740
gene id: 28091:EL309_RS02740
uniprot id: A0A3S4ZJY6
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the trans-sulfuration enzymes family.

28091:EL309 RS05890
gene id: 28091:EL309_RS05890
uniprot id: A0A448VN99
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

28091:EL309 RS05125
gene id: 28091:EL309_RS05125
uniprot id: A0A3S5C402
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

28091:EL309 RS01065
gene id: 28091:EL309_RS01065
uniprot id: A0A448VI65
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

28091:EL309 RS05045
gene id: 28091:EL309_RS05045
uniprot id: A0A3S5C3Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

28091:EL309 RS02685
gene id: 28091:EL309_RS02685
uniprot id: A0A448VK12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

28091:EL309 RS04140
gene id: 28091:EL309_RS04140
uniprot id: A0A448VLN7
names: Cofactor
messages: Can also use Mn(2+) ion.

28091:EL309 RS01025
gene id: 28091:EL309_RS01025
uniprot id: A0A448VI25
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

28091:EL309 RS01815
gene id: 28091:EL309_RS01815
uniprot id: A0A448VJ33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

28091:EL309 RS09095
gene id: 28091:EL309_RS09095
uniprot id: A0A3S4YSV0
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS04110
gene id: 28091:EL309_RS04110
uniprot id: A0A3S5F9N7
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS08500
gene id: 28091:EL309_RS08500
uniprot id: A0A448VPT2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

28091:EL309 RS08885
gene id: 28091:EL309_RS08885
uniprot id: A0A3S5ABS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

28091:EL309 RS10545
gene id: 28091:EL309_RS10545
uniprot id: A0A3S5B6D0
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS02130
gene id: 28091:EL309_RS02130
uniprot id: A0A448VJF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

28091:EL309 RS00405
gene id: 28091:EL309_RS00405
uniprot id: A0A3S4YN78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

28091:EL309 RS09970
gene id: 28091:EL309_RS09970
uniprot id: A0A448VQJ1
names: Similarity
messages: Belongs to the HesB/IscA family.

28091:EL309 RS05500
gene id: 28091:EL309_RS05500
uniprot id: A0A448VN79
names: Similarity
messages: Belongs to the MlaA family.

28091:EL309 RS02215
gene id: 28091:EL309_RS02215
uniprot id: A0A3S4Z731
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

28091:EL309 RS05030
gene id: 28091:EL309_RS05030
uniprot id: A0A3S5B4I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

28091:EL309 RS01880
gene id: 28091:EL309_RS01880
uniprot id: A0A448VJ48
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

28091:EL309 RS05930
gene id: 28091:EL309_RS05930
uniprot id: A0A448VNF7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

28091:EL309 RS04340
gene id: 28091:EL309_RS04340
uniprot id: A0A3S5A9N1
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

28091:EL309 RS10335
gene id: 28091:EL309_RS10335
uniprot id: A0A448VQT7
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

28091:EL309 RS02730
gene id: 28091:EL309_RS02730
uniprot id: A0A448VK50
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

28091:EL309 RS08165
gene id: 28091:EL309_RS08165
uniprot id: A0A3S4ZE40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

28091:EL309 RS04730
gene id: 28091:EL309_RS04730
uniprot id: A0A448VMH3
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS07340
gene id: 28091:EL309_RS07340
uniprot id: A0A448VP10
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

28091:EL309 RS05470
gene id: 28091:EL309_RS05470
uniprot id: A0A448VN87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

28091:EL309 RS05800
gene id: 28091:EL309_RS05800
uniprot id: A0A3S5B4W3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

28091:EL309 RS04870
gene id: 28091:EL309_RS04870
uniprot id: A0A448VMJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

28091:EL309 RS09385
gene id: 28091:EL309_RS09385
uniprot id: A0A448VQ82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

28091:EL309 RS10575
gene id: 28091:EL309_RS10575
uniprot id: A0A448VQT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

28091:EL309 RS06550
gene id: 28091:EL309_RS06550
uniprot id: A0A3S5CAK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

28091:EL309 RS00795
gene id: 28091:EL309_RS00795
uniprot id: A0A3S5F9G3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

28091:EL309 RS02220
gene id: 28091:EL309_RS02220
uniprot id: A0A448VJJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

28091:EL309 RS09550
gene id: 28091:EL309_RS09550
uniprot id: A0A3S4ZAJ9
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

28091:EL309 RS06165
gene id: 28091:EL309_RS06165
uniprot id: A0A448VNH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EfeM/EfeO family.
messages: Cell outer membrane
messages: Membrane

28091:EL309 RS05220
gene id: 28091:EL309_RS05220
uniprot id: A0A3S5B4N9
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

28091:EL309 RS10045
gene id: 28091:EL309_RS10045
uniprot id: A0A3S4Z5Q1
names: Subcellular Location Annotation
messages: Secreted

28091:EL309 RS09555
gene id: 28091:EL309_RS09555
uniprot id: A0A3S5C4K6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

28091:EL309 RS10115
gene id: 28091:EL309_RS10115
uniprot id: A0A448VQL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Slam family.
messages: Cell outer membrane
messages: Membrane

28091:EL309 RS04030
gene id: 28091:EL309_RS04030
uniprot id: A0A3S4YQR6
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

28091:EL309 RS07925
gene id: 28091:EL309_RS07925
uniprot id: A0A448VPH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

28091:EL309 RS01765
gene id: 28091:EL309_RS01765
uniprot id: A0A3S4YP85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

28091:EL309 RS08470
gene id: 28091:EL309_RS08470
uniprot id: A0A448VPS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

28091:EL309 RS00860
gene id: 28091:EL309_RS00860
uniprot id: A0A448VHX3
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

28091:EL309 RS06800
gene id: 28091:EL309_RS06800
uniprot id: A0A3S5CAL6
names: Similarity
messages: Belongs to the PhzF family.

28091:EL309 RS09945
gene id: 28091:EL309_RS09945
uniprot id: A0A3S5C4L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

28091:EL309 RS00595
gene id: 28091:EL309_RS00595
uniprot id: A0A3S5C2V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

28091:EL309 RS10215
gene id: 28091:EL309_RS10215
uniprot id: A0A3S5F9W6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

28091:EL309 RS05760
gene id: 28091:EL309_RS05760
uniprot id: A0A448VN96
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

28091:EL309 RS06525
gene id: 28091:EL309_RS06525
uniprot id: A0A3S5B537
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

28091:EL309 RS04125
gene id: 28091:EL309_RS04125
uniprot id: A0A448VLP0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

28091:EL309 RS10155
gene id: 28091:EL309_RS10155
uniprot id: A0A448VQL8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

28091:EL309 RS01280
gene id: 28091:EL309_RS01280
uniprot id: A0A3S4Z6D4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28091:EL309 RS06535
gene id: 28091:EL309_RS06535
uniprot id: A0A3S4YS06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

28091:EL309 RS03010
gene id: 28091:EL309_RS03010
uniprot id: A0A448VKA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

28091:EL309 RS03805
gene id: 28091:EL309_RS03805
uniprot id: A0A448VLB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

28091:EL309 RS01425
gene id: 28091:EL309_RS01425
uniprot id: A0A3S4YNZ1
names: Similarity
messages: Belongs to the pirin family.

28091:EL309 RS02835
gene id: 28091:EL309_RS02835
uniprot id: A0A448VK68
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
messages: Homodimer.

28091:EL309 RS06690
gene id: 28091:EL309_RS06690
uniprot id: A0A448VNS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

28091:EL309 RS08955
gene id: 28091:EL309_RS08955
uniprot id: A0A448VPX6
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

28091:EL309 RS09155
gene id: 28091:EL309_RS09155
uniprot id: A0A3S5ABV4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

28091:EL309 RS05295
gene id: 28091:EL309_RS05295
uniprot id: A0A3S4YRK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

28091:EL309 RS09135
gene id: 28091:EL309_RS09135
uniprot id: A0A448VQ32
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

28091:EL309 RS05165
gene id: 28091:EL309_RS05165
uniprot id: A0A3S5AAB5
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS09410
gene id: 28091:EL309_RS09410
uniprot id: A0A3S4ZMS9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

28091:EL309 RS00920
gene id: 28091:EL309_RS00920
uniprot id: A0A3S4YNK9
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS04505
gene id: 28091:EL309_RS04505
uniprot id: A0A3S4YR19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

28091:EL309 RS04770
gene id: 28091:EL309_RS04770
uniprot id: A0A448VMF4
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

28091:EL309 RS07820
gene id: 28091:EL309_RS07820
uniprot id: A0A448VPC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

28091:EL309 RS05020
gene id: 28091:EL309_RS05020
uniprot id: A0A3S4Z411
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

28091:EL309 RS09580
gene id: 28091:EL309_RS09580
uniprot id: A0A3S4ZEI5
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS06440
gene id: 28091:EL309_RS06440
uniprot id: A0A448VNQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

28091:EL309 RS01170
gene id: 28091:EL309_RS01170
uniprot id: A0A3S4Z6B3
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

28091:EL309 RS01520
gene id: 28091:EL309_RS01520
uniprot id: A0A3S4ZAY6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS07870
gene id: 28091:EL309_RS07870
uniprot id: A0A3S5CAS0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

28091:EL309 RS03380
gene id: 28091:EL309_RS03380
uniprot id: A0A3S4ZC33
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

28091:EL309 RS01955
gene id: 28091:EL309_RS01955
uniprot id: A0A448VJ84
names: Similarity
messages: Belongs to the peptidase S41A family.

28091:EL309 RS08370
gene id: 28091:EL309_RS08370
uniprot id: A0A448VPW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Membrane

28091:EL309 RS08205
gene id: 28091:EL309_RS08205
uniprot id: A0A448VPT4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

28091:EL309 RS00270
gene id: 28091:EL309_RS00270
uniprot id: A0A3S5B1K0
names: Similarity
messages: Belongs to the pirin family.

28091:EL309 RS01680
gene id: 28091:EL309_RS01680
uniprot id: A0A448VIW6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

28091:EL309 RS01175
gene id: 28091:EL309_RS01175
uniprot id: A0A448VIA4
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

28091:EL309 RS06140
gene id: 28091:EL309_RS06140
uniprot id: A0A3S4YRX6
names: Similarity
messages: Belongs to the peptidase M16 family.

28091:EL309 RS01285
gene id: 28091:EL309_RS01285
uniprot id: A0A448VIE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

28091:EL309 RS04930
gene id: 28091:EL309_RS04930
uniprot id: A0A3S4ZCX6
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

28091:EL309 RS08660
gene id: 28091:EL309_RS08660
uniprot id: A0A3S4ZAB3
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

28091:EL309 RS02160
gene id: 28091:EL309_RS02160
uniprot id: A0A3S4Z722
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

28091:EL309 RS01415
gene id: 28091:EL309_RS01415
uniprot id: A0A3S5A7K4
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

28091:EL309 RS00970
gene id: 28091:EL309_RS00970
uniprot id: A0A3S4ZIR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

28091:EL309 RS03495
gene id: 28091:EL309_RS03495
uniprot id: A0A3S5B3M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

28091:EL309 RS09995
gene id: 28091:EL309_RS09995
uniprot id: A0A3S5B676
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

28091:EL309 RS05630
gene id: 28091:EL309_RS05630
uniprot id: A0A3S4ZLM3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

28091:EL309 RS06530
gene id: 28091:EL309_RS06530
uniprot id: A0A448VNQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

28091:EL309 RS07880
gene id: 28091:EL309_RS07880
uniprot id: A0A448VPD4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

28091:EL309 RS09515
gene id: 28091:EL309_RS09515
uniprot id: A0A3S5F9V9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

28091:EL309 RS02310
gene id: 28091:EL309_RS02310
uniprot id: A0A3S5C9N1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

28091:EL309 RS06105
gene id: 28091:EL309_RS06105
uniprot id: A0A3S4ZDG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

28091:EL309 RS06540
gene id: 28091:EL309_RS06540
uniprot id: A0A448VNM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

28091:EL309 RS01260
gene id: 28091:EL309_RS01260
uniprot id: A0A3S5F9H4
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

28091:EL309 RS01140
gene id: 28091:EL309_RS01140
uniprot id: A0A3S4YNR9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

28091:EL309 RS10210
gene id: 28091:EL309_RS10210
uniprot id: A0A3S5CB14
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

28091:EL309 RS04175
gene id: 28091:EL309_RS04175
uniprot id: A0A3S4Z8B2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

28091:EL309 RS01960
gene id: 28091:EL309_RS01960
uniprot id: A0A3S5C383
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

28091:EL309 RS01545
gene id: 28091:EL309_RS01545
uniprot id: A0A3S5C344
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

28091:EL309 RS06920
gene id: 28091:EL309_RS06920
uniprot id: A0A3S4YS60
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS03415
gene id: 28091:EL309_RS03415
uniprot id: A0A3S4Z7U6
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

28091:EL309 RS05950
gene id: 28091:EL309_RS05950
uniprot id: A0A3S4Z4G7
names: Similarity
messages: Belongs to the LOG family.

28091:EL309 RS01385
gene id: 28091:EL309_RS01385
uniprot id: A0A3S4YNX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

28091:EL309 RS01615
gene id: 28091:EL309_RS01615
uniprot id: A0A3S5B2G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

28091:EL309 RS07650
gene id: 28091:EL309_RS07650
uniprot id: A0A448VPB3
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

28091:EL309 RS01150
gene id: 28091:EL309_RS01150
uniprot id: A0A3S5F9H2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

28091:EL309 RS06670
gene id: 28091:EL309_RS06670
uniprot id: A0A3S5AB10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

28091:EL309 RS06620
gene id: 28091:EL309_RS06620
uniprot id: A0A3S4YS19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

28091:EL309 RS01455
gene id: 28091:EL309_RS01455
uniprot id: A0A3S5C331
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

28091:EL309 RS03145
gene id: 28091:EL309_RS03145
uniprot id: A0A448VKL0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS04440
gene id: 28091:EL309_RS04440
uniprot id: A0A448VLY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

28091:EL309 RS02800
gene id: 28091:EL309_RS02800
uniprot id: A0A3S4Z2S6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

28091:EL309 RS07215
gene id: 28091:EL309_RS07215
uniprot id: A0A448VP46
names: Similarity
messages: Belongs to the UPF0102 family.

28091:EL309 RS06595
gene id: 28091:EL309_RS06595
uniprot id: A0A448VNR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

28091:EL309 RS01920
gene id: 28091:EL309_RS01920
uniprot id: A0A3S5B2P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

28091:EL309 RS08650
gene id: 28091:EL309_RS08650
uniprot id: A0A448VPW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

28091:EL309 RS01725
gene id: 28091:EL309_RS01725
uniprot id: A0A3S4ZJA2
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

28091:EL309 RS08450
gene id: 28091:EL309_RS08450
uniprot id: A0A3S5C4H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

28091:EL309 RS10140
gene id: 28091:EL309_RS10140
uniprot id: A0A448VQU0
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

28091:EL309 RS07055
gene id: 28091:EL309_RS07055
uniprot id: A0A3S5F9T3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

28091:EL309 RS06210
gene id: 28091:EL309_RS06210
uniprot id: A0A3S4Z9G5
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

28091:EL309 RS10425
gene id: 28091:EL309_RS10425
uniprot id: A0A448VQR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

28091:EL309 RS00435
gene id: 28091:EL309_RS00435
uniprot id: A0A448VHE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

28091:EL309 RS02030
gene id: 28091:EL309_RS02030
uniprot id: A0A3S4YPF4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

28091:EL309 RS04280
gene id: 28091:EL309_RS04280
uniprot id: A0A448VLR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

28091:EL309 RS09720
gene id: 28091:EL309_RS09720
uniprot id: A0A3S4ZMW1
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS03950
gene id: 28091:EL309_RS03950
uniprot id: A0A448VLF2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS03030
gene id: 28091:EL309_RS03030
uniprot id: A0A448VKF7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

28091:EL309 RS05685
gene id: 28091:EL309_RS05685
uniprot id: A0A448VN56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

28091:EL309 RS05850
gene id: 28091:EL309_RS05850
uniprot id: A0A448VNA8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

28091:EL309 RS10270
gene id: 28091:EL309_RS10270
uniprot id: A0A448VQS2
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

28091:EL309 RS08825
gene id: 28091:EL309_RS08825
uniprot id: A0A448VPX3
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

28091:EL309 RS02165
gene id: 28091:EL309_RS02165
uniprot id: A0A448VJH2
names: Similarity
messages: Belongs to the UPF0237 family.

28091:EL309 RS05230
gene id: 28091:EL309_RS05230
uniprot id: A0A3S5CAE0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

28091:EL309 RS02635
gene id: 28091:EL309_RS02635
uniprot id: A0A448VK01
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

28091:EL309 RS05955
gene id: 28091:EL309_RS05955
uniprot id: A0A448VND2
names: Caution
names: Similarity
messages: Belongs to the UPF0391 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS06290
gene id: 28091:EL309_RS06290
uniprot id: A0A448VNR2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

28091:EL309 RS07455
gene id: 28091:EL309_RS07455
uniprot id: A0A3S4Z9W3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

28091:EL309 RS03235
gene id: 28091:EL309_RS03235
uniprot id: A0A448VKM2
names: Similarity
messages: Belongs to the peptidase S13 family.

28091:EL309 RS01780
gene id: 28091:EL309_RS01780
uniprot id: A0A448VJ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

28091:EL309 RS10170
gene id: 28091:EL309_RS10170
uniprot id: A0A3S5AC68
names: Similarity
messages: Belongs to the P(II) protein family.

28091:EL309 RS02040
gene id: 28091:EL309_RS02040
uniprot id: A0A3S5C9K5
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

28091:EL309 RS01230
gene id: 28091:EL309_RS01230
uniprot id: A0A3S4Z6C2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

28091:EL309 RS02015
gene id: 28091:EL309_RS02015
uniprot id: A0A3S4Z6Z1
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

28091:EL309 RS02430
gene id: 28091:EL309_RS02430
uniprot id: A0A3S5A8C5
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

28091:EL309 RS09885
gene id: 28091:EL309_RS09885
uniprot id: A0A3S5B666
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

28091:EL309 RS03910
gene id: 28091:EL309_RS03910
uniprot id: A0A3S4YQP7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

28091:EL309 RS01820
gene id: 28091:EL309_RS01820
uniprot id: A0A3S5F9I7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

28091:EL309 RS01075
gene id: 28091:EL309_RS01075
uniprot id: A0A448VI64
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

28091:EL309 RS06400
gene id: 28091:EL309_RS06400
uniprot id: A0A448VNM8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

28091:EL309 RS09960
gene id: 28091:EL309_RS09960
uniprot id: A0A448VQI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

28091:EL309 RS01335
gene id: 28091:EL309_RS01335
uniprot id: A0A448VIG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

28091:EL309 RS02200
gene id: 28091:EL309_RS02200
uniprot id: A0A3S5C9M0
names: Similarity
messages: Belongs to the SCO1/2 family.

28091:EL309 RS05960
gene id: 28091:EL309_RS05960
uniprot id: A0A448VNB5
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

28091:EL309 RS06415
gene id: 28091:EL309_RS06415
uniprot id: A0A448VNK8
names: Similarity
messages: Belongs to the Smg family.

28091:EL309 RS07825
gene id: 28091:EL309_RS07825
uniprot id: A0A448VPF5
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.

28091:EL309 RS04105
gene id: 28091:EL309_RS04105
uniprot id: A0A3S5CA31
names: Similarity
messages: Belongs to the UPF0053 family.

28091:EL309 RS07995
gene id: 28091:EL309_RS07995
uniprot id: A0A448VPP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

28091:EL309 RS02770
gene id: 28091:EL309_RS02770
uniprot id: A0A3S4YPZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

28091:EL309 RS04485
gene id: 28091:EL309_RS04485
uniprot id: A0A448VM19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

28091:EL309 RS08940
gene id: 28091:EL309_RS08940
uniprot id: A0A3S4ZEC7
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

28091:EL309 RS03305
gene id: 28091:EL309_RS03305
uniprot id: A0A448VKR2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

28091:EL309 RS01315
gene id: 28091:EL309_RS01315
uniprot id: A0A3S4Z1S0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

28091:EL309 RS00440
gene id: 28091:EL309_RS00440
uniprot id: A0A448VHE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

28091:EL309 RS06680
gene id: 28091:EL309_RS06680
uniprot id: A0A448VNS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

28091:EL309 RS06090
gene id: 28091:EL309_RS06090
uniprot id: A0A3S5C468
names: PTM
messages: Binds 1 heme group per subunit.

28091:EL309 RS07100
gene id: 28091:EL309_RS07100
uniprot id: A0A448VNX5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS08540
gene id: 28091:EL309_RS08540
uniprot id: A0A448VPP6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

28091:EL309 RS08365
gene id: 28091:EL309_RS08365
uniprot id: A0A3S4YSN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

28091:EL309 RS02720
gene id: 28091:EL309_RS02720
uniprot id: A0A3S4Z2R1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

28091:EL309 RS10330
gene id: 28091:EL309_RS10330
uniprot id: A0A3S5C4M3
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

28091:EL309 RS08615
gene id: 28091:EL309_RS08615
uniprot id: A0A448VPS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

28091:EL309 RS05695
gene id: 28091:EL309_RS05695
uniprot id: A0A3S5B4V2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

28091:EL309 RS10535
gene id: 28091:EL309_RS10535
uniprot id: A0A3S5ACE2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

28091:EL309 RS03960
gene id: 28091:EL309_RS03960
uniprot id: A0A3S5C3Q4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

28091:EL309 RS01895
gene id: 28091:EL309_RS01895
uniprot id: A0A3S4ZJE3
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS05820
gene id: 28091:EL309_RS05820
uniprot id: A0A448VNF4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

28091:EL309 RS03855
gene id: 28091:EL309_RS03855
uniprot id: A0A448VLD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

28091:EL309 RS06585
gene id: 28091:EL309_RS06585
uniprot id: A0A448VNQ7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

28091:EL309 RS03720
gene id: 28091:EL309_RS03720
uniprot id: A0A448VL65
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

28091:EL309 RS03685
gene id: 28091:EL309_RS03685
uniprot id: A0A3S5C9Z8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28091:EL309 RS04865
gene id: 28091:EL309_RS04865
uniprot id: A0A448VMF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

28091:EL309 RS08840
gene id: 28091:EL309_RS08840
uniprot id: A0A448VQ13
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS01195
gene id: 28091:EL309_RS01195
uniprot id: A0A448VIC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

28091:EL309 RS06660
gene id: 28091:EL309_RS06660
uniprot id: A0A3S5C488
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

28091:EL309 RS09570
gene id: 28091:EL309_RS09570
uniprot id: A0A448VQD5
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS04620
gene id: 28091:EL309_RS04620
uniprot id: A0A3S4Z3T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

28091:EL309 RS09560
gene id: 28091:EL309_RS09560
uniprot id: A0A448VQB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

28091:EL309 RS03985
gene id: 28091:EL309_RS03985
uniprot id: A0A448VLH5
names: Subcellular Location Annotation
messages: Cytoplasm

28091:EL309 RS09315
gene id: 28091:EL309_RS09315
uniprot id: A0A448VQI0
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS00530
gene id: 28091:EL309_RS00530
uniprot id: A0A3S4ZIG5
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS00390
gene id: 28091:EL309_RS00390
uniprot id: A0A3S5A6R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

28091:EL309 RS01400
gene id: 28091:EL309_RS01400
uniprot id: A0A3S4Z6H0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

28091:EL309 RS04435
gene id: 28091:EL309_RS04435
uniprot id: A0A3S5C3U1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

28091:EL309 RS08410
gene id: 28091:EL309_RS08410
uniprot id: A0A448VPN9
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

28091:EL309 RS06155
gene id: 28091:EL309_RS06155
uniprot id: A0A3S4ZLT1
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS06560
gene id: 28091:EL309_RS06560
uniprot id: A0A3S4Z4M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

28091:EL309 RS00455
gene id: 28091:EL309_RS00455
uniprot id: A0A448VHG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

28091:EL309 RS01675
gene id: 28091:EL309_RS01675
uniprot id: A0A448VIU6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS08625
gene id: 28091:EL309_RS08625
uniprot id: A0A3S4ZML4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

28091:EL309 RS09335
gene id: 28091:EL309_RS09335
uniprot id: A0A448VQ69
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

28091:EL309 RS08090
gene id: 28091:EL309_RS08090
uniprot id: A0A3S5ABJ8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

28091:EL309 RS10125
gene id: 28091:EL309_RS10125
uniprot id: A0A448VQM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

28091:EL309 RS08385
gene id: 28091:EL309_RS08385
uniprot id: A0A3S5CAU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

28091:EL309 RS03260
gene id: 28091:EL309_RS03260
uniprot id: A0A3S4YQA1
names: Similarity
messages: Belongs to the UPF0434 family.

28091:EL309 RS06295
gene id: 28091:EL309_RS06295
uniprot id: A0A3S5F9S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

28091:EL309 RS02945
gene id: 28091:EL309_RS02945
uniprot id: A0A448VKD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

28091:EL309 RS09130
gene id: 28091:EL309_RS09130
uniprot id: A0A3S4ZAG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

28091:EL309 RS00610
gene id: 28091:EL309_RS00610
uniprot id: A0A448VHM8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

28091:EL309 RS01180
gene id: 28091:EL309_RS01180
uniprot id: A0A3S5A7D8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

28091:EL309 RS09170
gene id: 28091:EL309_RS09170
uniprot id: A0A3S5B5Z4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

28091:EL309 RS00420
gene id: 28091:EL309_RS00420
uniprot id: A0A448VHE7
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

28091:EL309 RS08570
gene id: 28091:EL309_RS08570
uniprot id: A0A448VPU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

28091:EL309 RS05570
gene id: 28091:EL309_RS05570
uniprot id: A0A3S5F9R8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

28091:EL309 RS04575
gene id: 28091:EL309_RS04575
uniprot id: A0A3S4Z8K0
names: Similarity
messages: Belongs to the WrbA family.

28091:EL309 RS10490
gene id: 28091:EL309_RS10490
uniprot id: A0A3S5CB28
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

28091:EL309 RS00555
gene id: 28091:EL309_RS00555
uniprot id: A0A3S5C2U8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

28091:EL309 RS02830
gene id: 28091:EL309_RS02830
uniprot id: A0A448VK88
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

28091:EL309 RS03015
gene id: 28091:EL309_RS03015
uniprot id: A0A3S4ZK38
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

28091:EL309 RS08710
gene id: 28091:EL309_RS08710
uniprot id: A0A448VPV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

28091:EL309 RS09370
gene id: 28091:EL309_RS09370
uniprot id: A0A448VQ62
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

28091:EL309 RS02645
gene id: 28091:EL309_RS02645
uniprot id: A0A3S4Z2P2
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

28091:EL309 RS03035
gene id: 28091:EL309_RS03035
uniprot id: A0A3S5A8R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

28091:EL309 RS08015
gene id: 28091:EL309_RS08015
uniprot id: A0A3S5ABI7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

28091:EL309 RS09120
gene id: 28091:EL309_RS09120
uniprot id: A0A3S4Z5G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

28091:EL309 RS09740
gene id: 28091:EL309_RS09740
uniprot id: A0A3S4Z5L8
names: Similarity
messages: Belongs to the RutC family.

28091:EL309 RS03190
gene id: 28091:EL309_RS03190
uniprot id: A0A448VKN6
names: Similarity
messages: Belongs to the DEAD box helicase family.

28091:EL309 RS06045
gene id: 28091:EL309_RS06045
uniprot id: A0A3S4ZLR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS00355
gene id: 28091:EL309_RS00355
uniprot id: A0A448VHA8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

28091:EL309 RS01560
gene id: 28091:EL309_RS01560
uniprot id: A0A3S4YP40
names: Subcellular Location Annotation
messages: Membrane

28091:EL309 RS04310
gene id: 28091:EL309_RS04310
uniprot id: A0A448VLT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

28091:EL309 RS09005
gene id: 28091:EL309_RS09005
uniprot id: A0A3S5CAW7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

28091:EL309 RS03280
gene id: 28091:EL309_RS03280
uniprot id: A0A3S5C3J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

28091:EL309 RS08110
gene id: 28091:EL309_RS08110
uniprot id: A0A3S4YSJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

28091:EL309 RS06110
gene id: 28091:EL309_RS06110
uniprot id: A0A3S5B4Z9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28091:EL309 RS02175
gene id: 28091:EL309_RS02175
uniprot id: A0A448VJF9
names: Similarity
messages: Belongs to the TrpF family.

28091:EL309 RS04855
gene id: 28091:EL309_RS04855
uniprot id: A0A3S4ZL63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

28091:EL309 RS08605
gene id: 28091:EL309_RS08605
uniprot id: A0A448VPU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

28091:EL309 RS03100
gene id: 28091:EL309_RS03100
uniprot id: A0A3S4YQ63
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

28091:EL309 RS07800
gene id: 28091:EL309_RS07800
uniprot id: A0A3S4ZA09
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

28091:EL309 RS04520
gene id: 28091:EL309_RS04520
uniprot id: A0A448VM52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

28091:EL309 RS02025
gene id: 28091:EL309_RS02025
uniprot id: A0A3S5B2R4
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

28091:EL309 RS04735
gene id: 28091:EL309_RS04735
uniprot id: A0A3S5F9Q0
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

28091:EL309 RS05315
gene id: 28091:EL309_RS05315
uniprot id: A0A448VN14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28091:EL309 RS05350
gene id: 28091:EL309_RS05350
uniprot id: A0A3S4Z945
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

28091:EL309 RS10230
gene id: 28091:EL309_RS10230
uniprot id: A0A448VQQ6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

28091:EL309 RS09600
gene id: 28091:EL309_RS09600
uniprot id: A0A448VQE1
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

28091:EL309 RS01730
gene id: 28091:EL309_RS01730
uniprot id: A0A448VIZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane