279238:SARO RS11530
gene id: 279238:SARO_RS11530
uniprot id: Q2G5Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

279238:SARO RS09205
gene id: 279238:SARO_RS09205
uniprot id: Q2G794
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

279238:SARO RS08500
gene id: 279238:SARO_RS08500
uniprot id: Q2G7N7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

279238:SARO RS15485
gene id: 279238:SARO_RS15485
uniprot id: Q2G3T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

279238:SARO RS10575
gene id: 279238:SARO_RS10575
uniprot id: Q2G6I1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

279238:SARO RS00120
gene id: 279238:SARO_RS00120
uniprot id: Q2GCD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

279238:SARO RS10695
gene id: 279238:SARO_RS10695
uniprot id: Q2G6F7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

279238:SARO RS05460
gene id: 279238:SARO_RS05460
uniprot id: Q2G9D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

279238:SARO RS11305
gene id: 279238:SARO_RS11305
uniprot id: Q2G639
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

279238:SARO RS06710
gene id: 279238:SARO_RS06710
uniprot id: Q2G8N8
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

279238:SARO RS09125
gene id: 279238:SARO_RS09125
uniprot id: Q2G7B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS11550
gene id: 279238:SARO_RS11550
uniprot id: Q2G5Z2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

279238:SARO RS17160
gene id: 279238:SARO_RS17160
uniprot id: A4XDV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS18155
gene id: 279238:SARO_RS18155
uniprot id: A4XEF5
names: Similarity
messages: Belongs to the Gfa family.

279238:SARO RS05105
gene id: 279238:SARO_RS05105
uniprot id: Q2G9K6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

279238:SARO RS02425
gene id: 279238:SARO_RS02425
uniprot id: Q2GB42
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

279238:SARO RS08660
gene id: 279238:SARO_RS08660
uniprot id: Q2G7K3
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

279238:SARO RS01700
gene id: 279238:SARO_RS01700
uniprot id: Q2GBI6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

279238:SARO RS14885
gene id: 279238:SARO_RS14885
uniprot id: Q2G452
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

279238:SARO RS09840
gene id: 279238:SARO_RS09840
uniprot id: Q2G6X2
names: Similarity
messages: Belongs to the YkuD family.

279238:SARO RS07705
gene id: 279238:SARO_RS07705
uniprot id: Q2G844
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

279238:SARO RS09115
gene id: 279238:SARO_RS09115
uniprot id: Q2G7B2
names: Similarity
messages: Belongs to the cytochrome P450 family.

279238:SARO RS11055
gene id: 279238:SARO_RS11055
uniprot id: Q2G687
names: Similarity
messages: Belongs to the ParB family.

279238:SARO RS05640
gene id: 279238:SARO_RS05640
uniprot id: Q2G997
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

279238:SARO RS16570
gene id: 279238:SARO_RS16570
uniprot id: Q2G373
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

279238:SARO RS14125
gene id: 279238:SARO_RS14125
uniprot id: Q2G4K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

279238:SARO RS09485
gene id: 279238:SARO_RS09485
uniprot id: Q2G739
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

279238:SARO RS01925
gene id: 279238:SARO_RS01925
uniprot id: Q2GBE0
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

279238:SARO RS08930
gene id: 279238:SARO_RS08930
uniprot id: Q2G7E9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

279238:SARO RS05065
gene id: 279238:SARO_RS05065
uniprot id: Q2G9L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

279238:SARO RS13155
gene id: 279238:SARO_RS13155
uniprot id: Q2G528
names: Similarity
messages: Belongs to the glutamine synthetase family.

279238:SARO RS19980
gene id: 279238:SARO_RS19980
uniprot id: A4XFG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aromatic amine dehydrogenase light chain family.
messages: Heterotetramer of two light and two heavy chains.
messages: Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin.
messages: Periplasm

279238:SARO RS11505
gene id: 279238:SARO_RS11505
uniprot id: Q2G601
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

279238:SARO RS13570
gene id: 279238:SARO_RS13570
uniprot id: Q2G4W4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

279238:SARO RS05850
gene id: 279238:SARO_RS05850
uniprot id: Q2G955
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

279238:SARO RS09085
gene id: 279238:SARO_RS09085
uniprot id: Q2G7B8
names: Similarity
messages: Belongs to the LOG family.

279238:SARO RS13460
gene id: 279238:SARO_RS13460
uniprot id: Q2G4Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

279238:SARO RS06510
gene id: 279238:SARO_RS06510
uniprot id: Q2G8S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

279238:SARO RS18765
gene id: 279238:SARO_RS18765
uniprot id: A4XES7
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

279238:SARO RS11515
gene id: 279238:SARO_RS11515
uniprot id: Q2G5Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

279238:SARO RS15740
gene id: 279238:SARO_RS15740
uniprot id: Q2G3N9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

279238:SARO RS05700
gene id: 279238:SARO_RS05700
uniprot id: Q2G985
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

279238:SARO RS00985
gene id: 279238:SARO_RS00985
uniprot id: Q2GBX7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

279238:SARO RS11485
gene id: 279238:SARO_RS11485
uniprot id: Q2G605
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

279238:SARO RS06910
gene id: 279238:SARO_RS06910
uniprot id: Q2G8K1
names: Similarity
messages: Belongs to the Skp family.

279238:SARO RS10535
gene id: 279238:SARO_RS10535
uniprot id: Q2G6J0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

279238:SARO RS18500
gene id: 279238:SARO_RS18500
uniprot id: A4XEM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS08390
gene id: 279238:SARO_RS08390
uniprot id: Q2G7Q9
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS10210
gene id: 279238:SARO_RS10210
uniprot id: Q2G6Q4
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS08070
gene id: 279238:SARO_RS08070
uniprot id: Q2G7X3
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS16430
gene id: 279238:SARO_RS16430
uniprot id: Q2G3A2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

279238:SARO RS03500
gene id: 279238:SARO_RS03500
uniprot id: Q2GAH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

279238:SARO RS18475
gene id: 279238:SARO_RS18475
uniprot id: A4XEL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS03705
gene id: 279238:SARO_RS03705
uniprot id: Q2GAD5
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

279238:SARO RS15750
gene id: 279238:SARO_RS15750
uniprot id: Q2G3N7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

279238:SARO RS10875
gene id: 279238:SARO_RS10875
uniprot id: Q2G6C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

279238:SARO RS07045
gene id: 279238:SARO_RS07045
uniprot id: Q2G8H4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

279238:SARO RS03715
gene id: 279238:SARO_RS03715
uniprot id: Q2GAD3
names: Cofactor
messages: Binds 1 zinc ion per subunit.

279238:SARO RS11980
gene id: 279238:SARO_RS11980
uniprot id: Q2G5Q6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

279238:SARO RS00975
gene id: 279238:SARO_RS00975
uniprot id: Q2GBX9
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

279238:SARO RS13430
gene id: 279238:SARO_RS13430
uniprot id: Q2G4Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

279238:SARO RS03515
gene id: 279238:SARO_RS03515
uniprot id: Q2GAH3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

279238:SARO RS00655
gene id: 279238:SARO_RS00655
uniprot id: Q2GC42
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

279238:SARO RS01940
gene id: 279238:SARO_RS01940
uniprot id: Q2GBD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

279238:SARO RS09320
gene id: 279238:SARO_RS09320
uniprot id: Q2G772
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

279238:SARO RS04475
gene id: 279238:SARO_RS04475
uniprot id: Q2G9Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS14590
gene id: 279238:SARO_RS14590
uniprot id: Q2G4B0
names: Similarity
messages: Belongs to the UPF0311 family.

279238:SARO RS16390
gene id: 279238:SARO_RS16390
uniprot id: Q2G3B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

279238:SARO RS05220
gene id: 279238:SARO_RS05220
uniprot id: Q2G9I1
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

279238:SARO RS08835
gene id: 279238:SARO_RS08835
uniprot id: Q2G7G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

279238:SARO RS14130
gene id: 279238:SARO_RS14130
uniprot id: Q2G4K2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

279238:SARO RS18990
gene id: 279238:SARO_RS18990
uniprot id: A4XEX1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

279238:SARO RS06380
gene id: 279238:SARO_RS06380
uniprot id: Q2G8V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

279238:SARO RS18240
gene id: 279238:SARO_RS18240
uniprot id: A4XEH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS18660
gene id: 279238:SARO_RS18660
uniprot id: A4XEQ6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

279238:SARO RS06345
gene id: 279238:SARO_RS06345
uniprot id: Q2G8W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

279238:SARO RS17015
gene id: 279238:SARO_RS17015
uniprot id: A4XDS7
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

279238:SARO RS01395
gene id: 279238:SARO_RS01395
uniprot id: Q2GBP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

279238:SARO RS18710
gene id: 279238:SARO_RS18710
uniprot id: A4XER6
names: Similarity
messages: Belongs to the RelE toxin family.

279238:SARO RS11150
gene id: 279238:SARO_RS11150
uniprot id: Q2G669
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

279238:SARO RS10020
gene id: 279238:SARO_RS10020
uniprot id: Q2G6U1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

279238:SARO RS07770
gene id: 279238:SARO_RS07770
uniprot id: Q2G832
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

279238:SARO RS16440
gene id: 279238:SARO_RS16440
uniprot id: Q2G3A0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

279238:SARO RS09930
gene id: 279238:SARO_RS09930
uniprot id: Q2G6V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

279238:SARO RS01670
gene id: 279238:SARO_RS01670
uniprot id: Q2GBJ2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

279238:SARO RS03100
gene id: 279238:SARO_RS03100
uniprot id: Q2GAQ6
names: Similarity
messages: Belongs to the MT-A70-like family.

279238:SARO RS06285
gene id: 279238:SARO_RS06285
uniprot id: Q2G8X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

279238:SARO RS08980
gene id: 279238:SARO_RS08980
uniprot id: Q2G7D9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

279238:SARO RS12145
gene id: 279238:SARO_RS12145
uniprot id: Q2G5M3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

279238:SARO RS06135
gene id: 279238:SARO_RS06135
uniprot id: Q2G901
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

279238:SARO RS00585
gene id: 279238:SARO_RS00585
uniprot id: Q2GC57
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

279238:SARO RS19835
gene id: 279238:SARO_RS19835
uniprot id: A4XFE0
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS06620
gene id: 279238:SARO_RS06620
uniprot id: Q2G8Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

279238:SARO RS02700
gene id: 279238:SARO_RS02700
uniprot id: Q2GAY4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

279238:SARO RS06780
gene id: 279238:SARO_RS06780
uniprot id: Q2G8M6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

279238:SARO RS05655
gene id: 279238:SARO_RS05655
uniprot id: Q2G994
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

279238:SARO RS09010
gene id: 279238:SARO_RS09010
uniprot id: Q2G7D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

279238:SARO RS05650
gene id: 279238:SARO_RS05650
uniprot id: Q2G995
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

279238:SARO RS04415
gene id: 279238:SARO_RS04415
uniprot id: Q2G9Z6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

279238:SARO RS12560
gene id: 279238:SARO_RS12560
uniprot id: Q2G5E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

279238:SARO RS01345
gene id: 279238:SARO_RS01345
uniprot id: Q2GBQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

279238:SARO RS16810
gene id: 279238:SARO_RS16810
uniprot id: Q2G328
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

279238:SARO RS14170
gene id: 279238:SARO_RS14170
uniprot id: Q2G4J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

279238:SARO RS14370
gene id: 279238:SARO_RS14370
uniprot id: Q2G4F4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

279238:SARO RS02275
gene id: 279238:SARO_RS02275
uniprot id: Q2GB71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS12370
gene id: 279238:SARO_RS12370
uniprot id: Q2G5H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS12285
gene id: 279238:SARO_RS12285
uniprot id: Q2G5J6
names: Similarity
messages: Belongs to the FGGY kinase family.

279238:SARO RS03435
gene id: 279238:SARO_RS03435
uniprot id: Q2GAI8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

279238:SARO RS16565
gene id: 279238:SARO_RS16565
uniprot id: Q2G374
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

279238:SARO RS04595
gene id: 279238:SARO_RS04595
uniprot id: Q2G9V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

279238:SARO RS10255
gene id: 279238:SARO_RS10255
uniprot id: Q2G6P5
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

279238:SARO RS04155
gene id: 279238:SARO_RS04155
uniprot id: Q2GA47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

279238:SARO RS05060
gene id: 279238:SARO_RS05060
uniprot id: Q2G9L5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

279238:SARO RS06480
gene id: 279238:SARO_RS06480
uniprot id: Q2G8T4
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS18985
gene id: 279238:SARO_RS18985
uniprot id: A4XEX0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

279238:SARO RS05665
gene id: 279238:SARO_RS05665
uniprot id: Q2G992
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

279238:SARO RS06920
gene id: 279238:SARO_RS06920
uniprot id: Q2G8J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

279238:SARO RS01470
gene id: 279238:SARO_RS01470
uniprot id: Q2GBN2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

279238:SARO RS14875
gene id: 279238:SARO_RS14875
uniprot id: Q2G454
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

279238:SARO RS06580
gene id: 279238:SARO_RS06580
uniprot id: Q2G8R4
names: Function
names: Similarity
messages: A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
messages: Belongs to the bacterial AtpI family.

279238:SARO RS00265
gene id: 279238:SARO_RS00265
uniprot id: Q2GCC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

279238:SARO RS02900
gene id: 279238:SARO_RS02900
uniprot id: Q2GAU5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

279238:SARO RS06950
gene id: 279238:SARO_RS06950
uniprot id: Q2G8J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

279238:SARO RS05675
gene id: 279238:SARO_RS05675
uniprot id: Q2G990
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

279238:SARO RS03060
gene id: 279238:SARO_RS03060
uniprot id: Q2GAR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS06225
gene id: 279238:SARO_RS06225
uniprot id: Q2G8Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

279238:SARO RS11325
gene id: 279238:SARO_RS11325
uniprot id: Q2G635
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

279238:SARO RS01630
gene id: 279238:SARO_RS01630
uniprot id: Q2GBK0
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

279238:SARO RS16350
gene id: 279238:SARO_RS16350
uniprot id: Q2G3B8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

279238:SARO RS07635
gene id: 279238:SARO_RS07635
uniprot id: Q2G859
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS01665
gene id: 279238:SARO_RS01665
uniprot id: Q2GBJ3
names: Function
messages: Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A.

279238:SARO RS05490
gene id: 279238:SARO_RS05490
uniprot id: Q2G9C8
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

279238:SARO RS04555
gene id: 279238:SARO_RS04555
uniprot id: Q2G9W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

279238:SARO RS10610
gene id: 279238:SARO_RS10610
uniprot id: Q2G6H4
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

279238:SARO RS08450
gene id: 279238:SARO_RS08450
uniprot id: Q2G7P7
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

279238:SARO RS00080
gene id: 279238:SARO_RS00080
uniprot id: Q2GCE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

279238:SARO RS19830
gene id: 279238:SARO_RS19830
uniprot id: A4XFD9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

279238:SARO RS14310
gene id: 279238:SARO_RS14310
uniprot id: Q2G4G6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

279238:SARO RS15460
gene id: 279238:SARO_RS15460
uniprot id: Q2G3U1
names: Similarity
messages: Belongs to the OprB family.

279238:SARO RS19090
gene id: 279238:SARO_RS19090
uniprot id: A4XEZ1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

279238:SARO RS02850
gene id: 279238:SARO_RS02850
uniprot id: Q2GAV5
names: Similarity
messages: Belongs to the universal stress protein A family.

279238:SARO RS19310
gene id: 279238:SARO_RS19310
uniprot id: A4XF36
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

279238:SARO RS17130
gene id: 279238:SARO_RS17130
uniprot id: A4XDU9
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

279238:SARO RS05145
gene id: 279238:SARO_RS05145
uniprot id: Q2G9J6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

279238:SARO RS04455
gene id: 279238:SARO_RS04455
uniprot id: Q2G9Y8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

279238:SARO RS01800
gene id: 279238:SARO_RS01800
uniprot id: Q2GBG5
names: Similarity
messages: Belongs to the virb1 family.

279238:SARO RS20260
gene id: 279238:SARO_RS20260
uniprot id: Q2G5G1
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS18675
gene id: 279238:SARO_RS18675
uniprot id: A4XEQ9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

279238:SARO RS05970
gene id: 279238:SARO_RS05970
uniprot id: Q2G933
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

279238:SARO RS03630
gene id: 279238:SARO_RS03630
uniprot id: Q2GAF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

279238:SARO RS04260
gene id: 279238:SARO_RS04260
uniprot id: Q2GA26
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

279238:SARO RS01540
gene id: 279238:SARO_RS01540
uniprot id: Q2GBL8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

279238:SARO RS13030
gene id: 279238:SARO_RS13030
uniprot id: Q2G552
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

279238:SARO RS11580
gene id: 279238:SARO_RS11580
uniprot id: Q2G5Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

279238:SARO RS05470
gene id: 279238:SARO_RS05470
uniprot id: Q2G9D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

279238:SARO RS12040
gene id: 279238:SARO_RS12040
uniprot id: Q2G5P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

279238:SARO RS05370
gene id: 279238:SARO_RS05370
uniprot id: Q2G9F2
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS06240
gene id: 279238:SARO_RS06240
uniprot id: Q2G8Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

279238:SARO RS03385
gene id: 279238:SARO_RS03385
uniprot id: Q2GAJ8
names: Cofactor
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

279238:SARO RS10705
gene id: 279238:SARO_RS10705
uniprot id: Q2G6F5
names: Similarity
messages: Belongs to the MreC family.

279238:SARO RS04340
gene id: 279238:SARO_RS04340
uniprot id: Q2GA11
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

279238:SARO RS00470
gene id: 279238:SARO_RS00470
uniprot id: Q2GC80
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

279238:SARO RS13120
gene id: 279238:SARO_RS13120
uniprot id: Q2G535
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

279238:SARO RS13625
gene id: 279238:SARO_RS13625
uniprot id: Q2G4V3
names: Similarity
messages: Belongs to the YkuD family.

279238:SARO RS18515
gene id: 279238:SARO_RS18515
uniprot id: A4XEM7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

279238:SARO RS12335
gene id: 279238:SARO_RS12335
uniprot id: Q2G5I6
names: Similarity
messages: Belongs to the cytochrome P450 family.

279238:SARO RS02840
gene id: 279238:SARO_RS02840
uniprot id: Q2GAV7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

279238:SARO RS07100
gene id: 279238:SARO_RS07100
uniprot id: Q2G8G3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

279238:SARO RS04640
gene id: 279238:SARO_RS04640
uniprot id: Q2G9U9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

279238:SARO RS08855
gene id: 279238:SARO_RS08855
uniprot id: Q2G7G4
names: Similarity
messages: Belongs to the glutathione peroxidase family.

279238:SARO RS10425
gene id: 279238:SARO_RS10425
uniprot id: Q2G6L1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

279238:SARO RS01625
gene id: 279238:SARO_RS01625
uniprot id: Q2GBK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

279238:SARO RS01425
gene id: 279238:SARO_RS01425
uniprot id: Q2GBP1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

279238:SARO RS04850
gene id: 279238:SARO_RS04850
uniprot id: Q2G9Q7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

279238:SARO RS08600
gene id: 279238:SARO_RS08600
uniprot id: Q2G7L5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

279238:SARO RS16695
gene id: 279238:SARO_RS16695
uniprot id: Q2G350
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 2 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.

279238:SARO RS05925
gene id: 279238:SARO_RS05925
uniprot id: Q2G940
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

279238:SARO RS02435
gene id: 279238:SARO_RS02435
uniprot id: Q2GB40
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

279238:SARO RS13240
gene id: 279238:SARO_RS13240
uniprot id: Q2G512
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

279238:SARO RS09915
gene id: 279238:SARO_RS09915
uniprot id: Q2G6V9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

279238:SARO RS06945
gene id: 279238:SARO_RS06945
uniprot id: Q2G8J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

279238:SARO RS13005
gene id: 279238:SARO_RS13005
uniprot id: Q2G557
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS06585
gene id: 279238:SARO_RS06585
uniprot id: Q2G8R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

279238:SARO RS04400
gene id: 279238:SARO_RS04400
uniprot id: Q2G9Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

279238:SARO RS16655
gene id: 279238:SARO_RS16655
uniprot id: Q2G358
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS09855
gene id: 279238:SARO_RS09855
uniprot id: Q2G6W9
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

279238:SARO RS00150
gene id: 279238:SARO_RS00150
uniprot id: Q2GCD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

279238:SARO RS00885
gene id: 279238:SARO_RS00885
uniprot id: Q2GBZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS03470
gene id: 279238:SARO_RS03470
uniprot id: Q2GAI1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

279238:SARO RS02660
gene id: 279238:SARO_RS02660
uniprot id: Q2GAZ2
names: Similarity
messages: Belongs to the sulfatase family.

279238:SARO RS10325
gene id: 279238:SARO_RS10325
uniprot id: Q2G6N1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

279238:SARO RS00095
gene id: 279238:SARO_RS00095
uniprot id: Q2GCE2
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

279238:SARO RS01120
gene id: 279238:SARO_RS01120
uniprot id: Q2GBV1
names: Similarity
messages: Belongs to the RNase T2 family.

279238:SARO RS18060
gene id: 279238:SARO_RS18060
uniprot id: A4XED6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS06615
gene id: 279238:SARO_RS06615
uniprot id: Q2G8Q7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

279238:SARO RS06300
gene id: 279238:SARO_RS06300
uniprot id: Q2G8X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

279238:SARO RS05280
gene id: 279238:SARO_RS05280
uniprot id: Q2G9H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

279238:SARO RS14195
gene id: 279238:SARO_RS14195
uniprot id: Q2G4I9
names: Function
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

279238:SARO RS04900
gene id: 279238:SARO_RS04900
uniprot id: Q2G9P7
names: Similarity
messages: Belongs to the PhoH family.

279238:SARO RS09065
gene id: 279238:SARO_RS09065
uniprot id: Q2G7C2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

279238:SARO RS00230
gene id: 279238:SARO_RS00230
uniprot id: Q2G2Y8
names: Similarity
messages: Belongs to the PhzF family.

279238:SARO RS10615
gene id: 279238:SARO_RS10615
uniprot id: Q2G6H3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

279238:SARO RS11905
gene id: 279238:SARO_RS11905
uniprot id: Q2G5S1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

279238:SARO RS08830
gene id: 279238:SARO_RS08830
uniprot id: Q2G7G9
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS02685
gene id: 279238:SARO_RS02685
uniprot id: Q2GAY7
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

279238:SARO RS13435
gene id: 279238:SARO_RS13435
uniprot id: Q2G4Z1
names: Similarity
messages: Belongs to the Dps family.

279238:SARO RS06245
gene id: 279238:SARO_RS06245
uniprot id: Q2G8Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

279238:SARO RS09845
gene id: 279238:SARO_RS09845
uniprot id: Q2G6X1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

279238:SARO RS15710
gene id: 279238:SARO_RS15710
uniprot id: Q2G3P5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

279238:SARO RS11670
gene id: 279238:SARO_RS11670
uniprot id: Q2G5W8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

279238:SARO RS14085
gene id: 279238:SARO_RS14085
uniprot id: Q2G4L1
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

279238:SARO RS18780
gene id: 279238:SARO_RS18780
uniprot id: A4XET0
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

279238:SARO RS09165
gene id: 279238:SARO_RS09165
uniprot id: Q2G7A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

279238:SARO RS02495
gene id: 279238:SARO_RS02495
uniprot id: Q2GB27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

279238:SARO RS16940
gene id: 279238:SARO_RS16940
uniprot id: Q2G302
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

279238:SARO RS07825
gene id: 279238:SARO_RS07825
uniprot id: Q2G821
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

279238:SARO RS13515
gene id: 279238:SARO_RS13515
uniprot id: Q2G4X5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

279238:SARO RS09615
gene id: 279238:SARO_RS09615
uniprot id: Q2G715
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

279238:SARO RS09550
gene id: 279238:SARO_RS09550
uniprot id: Q2G726
names: Similarity
messages: Belongs to the Nudix hydrolase family.

279238:SARO RS10780
gene id: 279238:SARO_RS10780
uniprot id: Q2G6E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

279238:SARO RS15495
gene id: 279238:SARO_RS15495
uniprot id: Q2G3T4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

279238:SARO RS16710
gene id: 279238:SARO_RS16710
uniprot id: Q2G347
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

279238:SARO RS04040
gene id: 279238:SARO_RS04040
uniprot id: Q2GA69
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

279238:SARO RS00175
gene id: 279238:SARO_RS00175
uniprot id: Q2G2Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

279238:SARO RS14650
gene id: 279238:SARO_RS14650
uniprot id: Q2G498
names: Similarity
messages: Belongs to the GST superfamily.

279238:SARO RS11910
gene id: 279238:SARO_RS11910
uniprot id: Q2G5S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

279238:SARO RS19595
gene id: 279238:SARO_RS19595
uniprot id: A4XF92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS05635
gene id: 279238:SARO_RS05635
uniprot id: Q2G998
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

279238:SARO RS10215
gene id: 279238:SARO_RS10215
uniprot id: Q2G6Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

279238:SARO RS12555
gene id: 279238:SARO_RS12555
uniprot id: Q2G5E2
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS19490
gene id: 279238:SARO_RS19490
uniprot id: A4XF71
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

279238:SARO RS06410
gene id: 279238:SARO_RS06410
uniprot id: Q2G8U7
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

279238:SARO RS11060
gene id: 279238:SARO_RS11060
uniprot id: Q2G686
names: Similarity
messages: Belongs to the DprA/Smf family.

279238:SARO RS09730
gene id: 279238:SARO_RS09730
uniprot id: Q2G6Z2
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

279238:SARO RS00880
gene id: 279238:SARO_RS00880
uniprot id: Q2GBZ7
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

279238:SARO RS20345
gene id: 279238:SARO_RS20345
uniprot id: Q2G3M3
names: Similarity
messages: Belongs to the MipA/OmpV family.

279238:SARO RS13485
gene id: 279238:SARO_RS13485
uniprot id: Q2G4Y1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

279238:SARO RS08430
gene id: 279238:SARO_RS08430
uniprot id: Q2G7Q1
names: Similarity
messages: Belongs to the AlaDH/PNT family.

279238:SARO RS00255
gene id: 279238:SARO_RS00255
uniprot id: Q2GCC3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

279238:SARO RS06880
gene id: 279238:SARO_RS06880
uniprot id: Q2G8K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

279238:SARO RS06085
gene id: 279238:SARO_RS06085
uniprot id: Q2G911
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

279238:SARO RS16525
gene id: 279238:SARO_RS16525
uniprot id: Q2G382
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

279238:SARO RS04995
gene id: 279238:SARO_RS04995
uniprot id: Q2G9M8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

279238:SARO RS03585
gene id: 279238:SARO_RS03585
uniprot id: Q2GAF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.

279238:SARO RS14785
gene id: 279238:SARO_RS14785
uniprot id: Q2G472
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

279238:SARO RS18800
gene id: 279238:SARO_RS18800
uniprot id: A4XET4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

279238:SARO RS14745
gene id: 279238:SARO_RS14745
uniprot id: Q2G480
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

279238:SARO RS08480
gene id: 279238:SARO_RS08480
uniprot id: Q2G7P1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

279238:SARO RS05980
gene id: 279238:SARO_RS05980
uniprot id: Q2G931
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

279238:SARO RS10800
gene id: 279238:SARO_RS10800
uniprot id: Q2G6D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

279238:SARO RS01020
gene id: 279238:SARO_RS01020
uniprot id: Q2GBX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

279238:SARO RS07570
gene id: 279238:SARO_RS07570
uniprot id: Q2G871
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS17890
gene id: 279238:SARO_RS17890
uniprot id: A4XEA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS10670
gene id: 279238:SARO_RS10670
uniprot id: Q2G6G2
names: Function
messages: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.

279238:SARO RS14315
gene id: 279238:SARO_RS14315
uniprot id: Q2G4G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

279238:SARO RS08915
gene id: 279238:SARO_RS08915
uniprot id: Q2G7F2
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

279238:SARO RS10175
gene id: 279238:SARO_RS10175
uniprot id: Q2G6R1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

279238:SARO RS00240
gene id: 279238:SARO_RS00240
uniprot id: Q2GCC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

279238:SARO RS09135
gene id: 279238:SARO_RS09135
uniprot id: Q2G7A8
names: Similarity
messages: Belongs to the Gfa family.

279238:SARO RS06870
gene id: 279238:SARO_RS06870
uniprot id: Q2G8K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

279238:SARO RS02105
gene id: 279238:SARO_RS02105
uniprot id: Q2GBA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

279238:SARO RS06310
gene id: 279238:SARO_RS06310
uniprot id: Q2G8W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

279238:SARO RS17280
gene id: 279238:SARO_RS17280
uniprot id: A4XDX7
names: Function
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Has multiple catalytic activities. Apart from catalyzing the oxidation of (+)-tartrate to oxaloglycolate, also converts meso-tartrate to D-glycerate and catalyzes the oxidative decarboxylation of D-malate to pyruvate.

279238:SARO RS16205
gene id: 279238:SARO_RS16205
uniprot id: Q2G3E7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

279238:SARO RS12725
gene id: 279238:SARO_RS12725
uniprot id: Q2G5B0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

279238:SARO RS08035
gene id: 279238:SARO_RS08035
uniprot id: Q2G7Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS00420
gene id: 279238:SARO_RS00420
uniprot id: Q2GC90
names: Similarity
messages: Belongs to the FGGY kinase family.

279238:SARO RS07405
gene id: 279238:SARO_RS07405
uniprot id: Q2G8A4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

279238:SARO RS03925
gene id: 279238:SARO_RS03925
uniprot id: Q2GA91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS19675
gene id: 279238:SARO_RS19675
uniprot id: A4XFA8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

279238:SARO RS12220
gene id: 279238:SARO_RS12220
uniprot id: Q2G5K9
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS13375
gene id: 279238:SARO_RS13375
uniprot id: Q2G503
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

279238:SARO RS14475
gene id: 279238:SARO_RS14475
uniprot id: Q2G4D3
names: Similarity
messages: Belongs to the UPF0260 family.

279238:SARO RS08475
gene id: 279238:SARO_RS08475
uniprot id: Q2G7P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS20025
gene id: 279238:SARO_RS20025
uniprot id: A4XFH8
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

279238:SARO RS06315
gene id: 279238:SARO_RS06315
uniprot id: Q2G8W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

279238:SARO RS05045
gene id: 279238:SARO_RS05045
uniprot id: Q2G9L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

279238:SARO RS14385
gene id: 279238:SARO_RS14385
uniprot id: Q2G4F1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

279238:SARO RS02110
gene id: 279238:SARO_RS02110
uniprot id: Q2GBA3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

279238:SARO RS10775
gene id: 279238:SARO_RS10775
uniprot id: Q2G6E3
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS04920
gene id: 279238:SARO_RS04920
uniprot id: Q2G9P3
names: Similarity
messages: Belongs to the ros/MucR family.

279238:SARO RS06990
gene id: 279238:SARO_RS06990
uniprot id: Q2G8I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

279238:SARO RS04450
gene id: 279238:SARO_RS04450
uniprot id: Q2G9Y9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

279238:SARO RS13230
gene id: 279238:SARO_RS13230
uniprot id: Q2G514
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS18775
gene id: 279238:SARO_RS18775
uniprot id: A4XES9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Catalyzes the conversion of 8'-apo-beta-carotenal to 13-apo-beta-carotenone and C12-dialdehyde. Has also weak activity with 4'-apo-beta-carotenal and gamma-carotene.
messages: Monomer.

279238:SARO RS00935
gene id: 279238:SARO_RS00935
uniprot id: Q2GBY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

279238:SARO RS14930
gene id: 279238:SARO_RS14930
uniprot id: Q2G443
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

279238:SARO RS08775
gene id: 279238:SARO_RS08775
uniprot id: Q2G7I0
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

279238:SARO RS09860
gene id: 279238:SARO_RS09860
uniprot id: Q2G6W8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

279238:SARO RS02035
gene id: 279238:SARO_RS02035
uniprot id: Q2GBB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

279238:SARO RS01050
gene id: 279238:SARO_RS01050
uniprot id: Q2GBW5
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

279238:SARO RS06705
gene id: 279238:SARO_RS06705
uniprot id: Q2G8N9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

279238:SARO RS05050
gene id: 279238:SARO_RS05050
uniprot id: Q2G9L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

279238:SARO RS15590
gene id: 279238:SARO_RS15590
uniprot id: Q2G3R8
names: Similarity
messages: Belongs to the YkuD family.

279238:SARO RS05040
gene id: 279238:SARO_RS05040
uniprot id: Q2G9L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

279238:SARO RS13080
gene id: 279238:SARO_RS13080
uniprot id: Q2G542
names: Similarity
messages: Belongs to the GST superfamily.

279238:SARO RS04005
gene id: 279238:SARO_RS04005
uniprot id: Q2GA76
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

279238:SARO RS10160
gene id: 279238:SARO_RS10160
uniprot id: Q2G6R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS01605
gene id: 279238:SARO_RS01605
uniprot id: Q2GBK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

279238:SARO RS02485
gene id: 279238:SARO_RS02485
uniprot id: Q2GB29
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

279238:SARO RS16605
gene id: 279238:SARO_RS16605
uniprot id: Q2G368
names: Similarity
messages: Belongs to the peptidase M1 family.

279238:SARO RS09095
gene id: 279238:SARO_RS09095
uniprot id: Q2G7B6
names: Similarity
messages: Belongs to the lycopene cyclase family.

279238:SARO RS02790
gene id: 279238:SARO_RS02790
uniprot id: Q2GAW7
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

279238:SARO RS02040
gene id: 279238:SARO_RS02040
uniprot id: Q2GBB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

279238:SARO RS00170
gene id: 279238:SARO_RS00170
uniprot id: Q2GCC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

279238:SARO RS09810
gene id: 279238:SARO_RS09810
uniprot id: Q2G6X7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

279238:SARO RS04560
gene id: 279238:SARO_RS04560
uniprot id: Q2G9W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

279238:SARO RS06630
gene id: 279238:SARO_RS06630
uniprot id: Q2G8Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

279238:SARO RS12995
gene id: 279238:SARO_RS12995
uniprot id: Q2G559
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

279238:SARO RS16560
gene id: 279238:SARO_RS16560
uniprot id: Q2G375
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

279238:SARO RS16630
gene id: 279238:SARO_RS16630
uniprot id: Q2G363
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

279238:SARO RS11625
gene id: 279238:SARO_RS11625
uniprot id: Q2G5X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

279238:SARO RS04440
gene id: 279238:SARO_RS04440
uniprot id: Q2G9Z1
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is located at the dimer interface.

279238:SARO RS17320
gene id: 279238:SARO_RS17320
uniprot id: A4XDY5
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS09650
gene id: 279238:SARO_RS09650
uniprot id: Q2G708
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.

279238:SARO RS10495
gene id: 279238:SARO_RS10495
uniprot id: Q2G6J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

279238:SARO RS18115
gene id: 279238:SARO_RS18115
uniprot id: A4XEE7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

279238:SARO RS07240
gene id: 279238:SARO_RS07240
uniprot id: Q2G8D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

279238:SARO RS21370
gene id: 279238:SARO_RS21370
uniprot id: Q2G441
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

279238:SARO RS12505
gene id: 279238:SARO_RS12505
uniprot id: Q2G5F3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

279238:SARO RS11830
gene id: 279238:SARO_RS11830
uniprot id: Q2G5T5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

279238:SARO RS10330
gene id: 279238:SARO_RS10330
uniprot id: Q2G6N0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

279238:SARO RS02070
gene id: 279238:SARO_RS02070
uniprot id: Q2GBB1
names: Similarity
messages: Belongs to the Gfa family.

279238:SARO RS18100
gene id: 279238:SARO_RS18100
uniprot id: A4XEE4
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS04370
gene id: 279238:SARO_RS04370
uniprot id: Q2GA05
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

279238:SARO RS15985
gene id: 279238:SARO_RS15985
uniprot id: Q2G3J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS04220
gene id: 279238:SARO_RS04220
uniprot id: Q2GA34
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

279238:SARO RS17265
gene id: 279238:SARO_RS17265
uniprot id: A4XDX4
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

279238:SARO RS12545
gene id: 279238:SARO_RS12545
uniprot id: Q2G5E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

279238:SARO RS19575
gene id: 279238:SARO_RS19575
uniprot id: A4XF88
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

279238:SARO RS09295
gene id: 279238:SARO_RS09295
uniprot id: Q2G777
names: Similarity
messages: Belongs to the GSP E family.

279238:SARO RS09490
gene id: 279238:SARO_RS09490
uniprot id: Q2G738
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

279238:SARO RS05570
gene id: 279238:SARO_RS05570
uniprot id: Q2G9B1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

279238:SARO RS19680
gene id: 279238:SARO_RS19680
uniprot id: A4XFA9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

279238:SARO RS16370
gene id: 279238:SARO_RS16370
uniprot id: Q2G3B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

279238:SARO RS00570
gene id: 279238:SARO_RS00570
uniprot id: Q2GC60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

279238:SARO RS19280
gene id: 279238:SARO_RS19280
uniprot id: A4XF30
names: Similarity
messages: Belongs to the cytochrome P450 family.

279238:SARO RS16285
gene id: 279238:SARO_RS16285
uniprot id: Q2G3D0
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

279238:SARO RS11660
gene id: 279238:SARO_RS11660
uniprot id: Q2G5X0
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

279238:SARO RS01110
gene id: 279238:SARO_RS01110
uniprot id: Q2GBV3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

279238:SARO RS17880
gene id: 279238:SARO_RS17880
uniprot id: A4XEA0
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS16685
gene id: 279238:SARO_RS16685
uniprot id: Q2G352
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

279238:SARO RS11400
gene id: 279238:SARO_RS11400
uniprot id: Q2G620
names: Similarity
messages: Belongs to the peptidase S33 family.

279238:SARO RS11480
gene id: 279238:SARO_RS11480
uniprot id: Q2G606
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

279238:SARO RS01385
gene id: 279238:SARO_RS01385
uniprot id: Q2GBP9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

279238:SARO RS04165
gene id: 279238:SARO_RS04165
uniprot id: Q2GA45
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

279238:SARO RS07150
gene id: 279238:SARO_RS07150
uniprot id: Q2G8F3
names: Similarity
messages: Belongs to the peptidase S66 family.

279238:SARO RS07510
gene id: 279238:SARO_RS07510
uniprot id: Q2G884
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS03785
gene id: 279238:SARO_RS03785
uniprot id: Q2GAB9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

279238:SARO RS08545
gene id: 279238:SARO_RS08545
uniprot id: Q2G7M8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

279238:SARO RS05275
gene id: 279238:SARO_RS05275
uniprot id: Q2G9H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

279238:SARO RS05100
gene id: 279238:SARO_RS05100
uniprot id: Q2G9K7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

279238:SARO RS11650
gene id: 279238:SARO_RS11650
uniprot id: Q2G5X2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

279238:SARO RS02745
gene id: 279238:SARO_RS02745
uniprot id: Q2GAX5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

279238:SARO RS09760
gene id: 279238:SARO_RS09760
uniprot id: Q2G6Y7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

279238:SARO RS04295
gene id: 279238:SARO_RS04295
uniprot id: Q2GA20
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

279238:SARO RS01615
gene id: 279238:SARO_RS01615
uniprot id: Q2GBK3
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

279238:SARO RS07070
gene id: 279238:SARO_RS07070
uniprot id: Q2G8G9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

279238:SARO RS13525
gene id: 279238:SARO_RS13525
uniprot id: Q2G4X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

279238:SARO RS05025
gene id: 279238:SARO_RS05025
uniprot id: Q2G9M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

279238:SARO RS09870
gene id: 279238:SARO_RS09870
uniprot id: Q2G6W6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

279238:SARO RS00755
gene id: 279238:SARO_RS00755
uniprot id: Q2GC22
names: Similarity
messages: Belongs to the peptidase M24B family.

279238:SARO RS12605
gene id: 279238:SARO_RS12605
uniprot id: Q2G5D4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

279238:SARO RS09040
gene id: 279238:SARO_RS09040
uniprot id: Q2G7C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

279238:SARO RS06230
gene id: 279238:SARO_RS06230
uniprot id: Q2G8Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

279238:SARO RS05150
gene id: 279238:SARO_RS05150
uniprot id: Q2G9J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

279238:SARO RS09495
gene id: 279238:SARO_RS09495
uniprot id: Q2G737
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

279238:SARO RS09780
gene id: 279238:SARO_RS09780
uniprot id: Q2G6Y3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

279238:SARO RS14515
gene id: 279238:SARO_RS14515
uniprot id: Q2G4C5
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

279238:SARO RS03665
gene id: 279238:SARO_RS03665
uniprot id: Q2GAE3
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

279238:SARO RS02005
gene id: 279238:SARO_RS02005
uniprot id: Q2GBC4
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS18810
gene id: 279238:SARO_RS18810
uniprot id: A4XET6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

279238:SARO RS11245
gene id: 279238:SARO_RS11245
uniprot id: Q2G651
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

279238:SARO RS06980
gene id: 279238:SARO_RS06980
uniprot id: Q2G8I7
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

279238:SARO RS12135
gene id: 279238:SARO_RS12135
uniprot id: Q2G5M5
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS12495
gene id: 279238:SARO_RS12495
uniprot id: Q2G5F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

279238:SARO RS18490
gene id: 279238:SARO_RS18490
uniprot id: A4XEM2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

279238:SARO RS02985
gene id: 279238:SARO_RS02985
uniprot id: Q2GAS7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

279238:SARO RS12945
gene id: 279238:SARO_RS12945
uniprot id: Q2G569
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

279238:SARO RS07910
gene id: 279238:SARO_RS07910
uniprot id: Q2G804
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

279238:SARO RS17235
gene id: 279238:SARO_RS17235
uniprot id: A4XDW8
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

279238:SARO RS11525
gene id: 279238:SARO_RS11525
uniprot id: Q2G5Z7
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

279238:SARO RS16775
gene id: 279238:SARO_RS16775
uniprot id: Q2G335
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

279238:SARO RS05415
gene id: 279238:SARO_RS05415
uniprot id: Q2G9E3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

279238:SARO RS00600
gene id: 279238:SARO_RS00600
uniprot id: Q2GC54
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

279238:SARO RS10360
gene id: 279238:SARO_RS10360
uniprot id: Q2G6M4
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

279238:SARO RS14915
gene id: 279238:SARO_RS14915
uniprot id: Q2G446
names: Subcellular Location Annotation
messages: Cell inner membrane

279238:SARO RS18110
gene id: 279238:SARO_RS18110
uniprot id: A4XEE6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

279238:SARO RS03190
gene id: 279238:SARO_RS03190
uniprot id: Q2GAN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

279238:SARO RS04980
gene id: 279238:SARO_RS04980
uniprot id: Q2G9N1
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

279238:SARO RS18460
gene id: 279238:SARO_RS18460
uniprot id: A4XEL6
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

279238:SARO RS16275
gene id: 279238:SARO_RS16275
uniprot id: Q2G3D2
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

279238:SARO RS10370
gene id: 279238:SARO_RS10370
uniprot id: Q2G6M2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

279238:SARO RS17170
gene id: 279238:SARO_RS17170
uniprot id: A4XDV7
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

279238:SARO RS08360
gene id: 279238:SARO_RS08360
uniprot id: Q2G7R5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

279238:SARO RS02310
gene id: 279238:SARO_RS02310
uniprot id: Q2GB64
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS00030
gene id: 279238:SARO_RS00030
uniprot id: Q2GCF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

279238:SARO RS13380
gene id: 279238:SARO_RS13380
uniprot id: Q2G502
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

279238:SARO RS12690
gene id: 279238:SARO_RS12690
uniprot id: Q2G5B7
names: Similarity
messages: Belongs to the BolA/IbaG family.

279238:SARO RS02010
gene id: 279238:SARO_RS02010
uniprot id: Q2GBC3
names: Similarity
messages: Belongs to the band 7/mec-2 family.

279238:SARO RS04435
gene id: 279238:SARO_RS04435
uniprot id: Q2G9Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

279238:SARO RS10180
gene id: 279238:SARO_RS10180
uniprot id: Q2G6R0
names: Similarity
messages: Belongs to the TrpC family.

279238:SARO RS16190
gene id: 279238:SARO_RS16190
uniprot id: Q2G3F0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

279238:SARO RS04570
gene id: 279238:SARO_RS04570
uniprot id: Q2G9W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

279238:SARO RS14445
gene id: 279238:SARO_RS14445
uniprot id: Q2G4D9
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

279238:SARO RS05755
gene id: 279238:SARO_RS05755
uniprot id: Q2G975
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

279238:SARO RS12090
gene id: 279238:SARO_RS12090
uniprot id: Q2G5N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

279238:SARO RS12625
gene id: 279238:SARO_RS12625
uniprot id: Q2G5D0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

279238:SARO RS18220
gene id: 279238:SARO_RS18220
uniprot id: A4XEG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS08900
gene id: 279238:SARO_RS08900
uniprot id: Q2G7F5
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

279238:SARO RS19275
gene id: 279238:SARO_RS19275
uniprot id: A4XF28
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

279238:SARO RS12910
gene id: 279238:SARO_RS12910
uniprot id: Q2G576
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS02755
gene id: 279238:SARO_RS02755
uniprot id: Q2GAX3
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

279238:SARO RS17930
gene id: 279238:SARO_RS17930
uniprot id: A4XEB0
names: Similarity
messages: Belongs to the CapA family.

279238:SARO RS11225
gene id: 279238:SARO_RS11225
uniprot id: Q2G654
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

279238:SARO RS09265
gene id: 279238:SARO_RS09265
uniprot id: Q2G782
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

279238:SARO RS11520
gene id: 279238:SARO_RS11520
uniprot id: Q2G5Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

279238:SARO RS14920
gene id: 279238:SARO_RS14920
uniprot id: Q2G445
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

279238:SARO RS00710
gene id: 279238:SARO_RS00710
uniprot id: Q2GC31
names: Similarity
messages: Belongs to the UPF0262 family.

279238:SARO RS17380
gene id: 279238:SARO_RS17380
uniprot id: A4XDZ9
names: Similarity
messages: Belongs to the ParB family.

279238:SARO RS17070
gene id: 279238:SARO_RS17070
uniprot id: A4XDT7
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

279238:SARO RS16480
gene id: 279238:SARO_RS16480
uniprot id: Q2G391
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

279238:SARO RS17080
gene id: 279238:SARO_RS17080
uniprot id: A4XDT9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

279238:SARO RS07860
gene id: 279238:SARO_RS07860
uniprot id: Q2G814
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

279238:SARO RS00790
gene id: 279238:SARO_RS00790
uniprot id: Q2GC14
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS08300
gene id: 279238:SARO_RS08300
uniprot id: Q2G7S8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

279238:SARO RS15955
gene id: 279238:SARO_RS15955
uniprot id: Q2G3J7
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

279238:SARO RS07170
gene id: 279238:SARO_RS07170
uniprot id: Q2G8E9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

279238:SARO RS17285
gene id: 279238:SARO_RS17285
uniprot id: A4XDX8
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

279238:SARO RS09670
gene id: 279238:SARO_RS09670
uniprot id: Q2G704
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

279238:SARO RS15500
gene id: 279238:SARO_RS15500
uniprot id: Q2G3T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

279238:SARO RS05120
gene id: 279238:SARO_RS05120
uniprot id: Q2G9K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

279238:SARO RS14490
gene id: 279238:SARO_RS14490
uniprot id: Q2G4D0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

279238:SARO RS18425
gene id: 279238:SARO_RS18425
uniprot id: A4XEK9
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS06010
gene id: 279238:SARO_RS06010
uniprot id: Q2G925
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

279238:SARO RS09635
gene id: 279238:SARO_RS09635
uniprot id: Q2G711
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

279238:SARO RS07950
gene id: 279238:SARO_RS07950
uniprot id: Q2G7Z7
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.

279238:SARO RS13440
gene id: 279238:SARO_RS13440
uniprot id: Q2G4Z0
names: Similarity
messages: Belongs to the GSP N family.

279238:SARO RS00580
gene id: 279238:SARO_RS00580
uniprot id: Q2GC58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

279238:SARO RS14285
gene id: 279238:SARO_RS14285
uniprot id: Q2G4H1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

279238:SARO RS16620
gene id: 279238:SARO_RS16620
uniprot id: Q2G365
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

279238:SARO RS11820
gene id: 279238:SARO_RS11820
uniprot id: Q2G5T7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

279238:SARO RS04970
gene id: 279238:SARO_RS04970
uniprot id: Q2G9N3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

279238:SARO RS12295
gene id: 279238:SARO_RS12295
uniprot id: Q2G5J4
names: Function
names: Similarity
messages: Belongs to the SsuD family.
messages: Part of the alkanesulfonate monooxygenase (sulfo-ASMO) pathway, a D-sulfoquinovose degradation pathway that enables the complete utilization of all carbons within sulfoquinovose (SQ) with concomitant production of inorganic sulfite (Ref.2). Catalyzes the oxidative desulfurization of sulfoquinovose to sulfite and 6-dehydro-D-glucose (Ref.2).

279238:SARO RS07020
gene id: 279238:SARO_RS07020
uniprot id: Q2G8H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

279238:SARO RS02555
gene id: 279238:SARO_RS02555
uniprot id: Q2GB15
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

279238:SARO RS00330
gene id: 279238:SARO_RS00330
uniprot id: Q2GCA8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

279238:SARO RS05630
gene id: 279238:SARO_RS05630
uniprot id: Q2G999
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

279238:SARO RS17260
gene id: 279238:SARO_RS17260
uniprot id: A4XDX3
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

279238:SARO RS07340
gene id: 279238:SARO_RS07340
uniprot id: Q2G8B7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

279238:SARO RS12525
gene id: 279238:SARO_RS12525
uniprot id: Q2G5E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

279238:SARO RS17185
gene id: 279238:SARO_RS17185
uniprot id: A4XDW0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

279238:SARO RS09835
gene id: 279238:SARO_RS09835
uniprot id: Q2G6X3
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS08995
gene id: 279238:SARO_RS08995
uniprot id: Q2G7D6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

279238:SARO RS01980
gene id: 279238:SARO_RS01980
uniprot id: Q2GBC9
names: Similarity
messages: Belongs to the universal stress protein A family.

279238:SARO RS06825
gene id: 279238:SARO_RS06825
uniprot id: Q2G8L7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

279238:SARO RS12720
gene id: 279238:SARO_RS12720
uniprot id: Q2G5B1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

279238:SARO RS06275
gene id: 279238:SARO_RS06275
uniprot id: Q2G8X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

279238:SARO RS11915
gene id: 279238:SARO_RS11915
uniprot id: Q2G5R9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

279238:SARO RS06340
gene id: 279238:SARO_RS06340
uniprot id: Q2G8W2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

279238:SARO RS11465
gene id: 279238:SARO_RS11465
uniprot id: Q2G609
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

279238:SARO RS06270
gene id: 279238:SARO_RS06270
uniprot id: Q2G8X6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

279238:SARO RS04015
gene id: 279238:SARO_RS04015
uniprot id: Q2GA74
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS14250
gene id: 279238:SARO_RS14250
uniprot id: Q2G4H8
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

279238:SARO RS09025
gene id: 279238:SARO_RS09025
uniprot id: Q2G7D0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

279238:SARO RS02945
gene id: 279238:SARO_RS02945
uniprot id: Q2GAT5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

279238:SARO RS03375
gene id: 279238:SARO_RS03375
uniprot id: Q2GAK0
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

279238:SARO RS12650
gene id: 279238:SARO_RS12650
uniprot id: Q2G5C5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

279238:SARO RS05660
gene id: 279238:SARO_RS05660
uniprot id: Q2G993
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

279238:SARO RS19375
gene id: 279238:SARO_RS19375
uniprot id: A4XF49
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

279238:SARO RS00780
gene id: 279238:SARO_RS00780
uniprot id: Q2GC16
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

279238:SARO RS18525
gene id: 279238:SARO_RS18525
uniprot id: A4XEM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS00610
gene id: 279238:SARO_RS00610
uniprot id: Q2GC51
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

279238:SARO RS00680
gene id: 279238:SARO_RS00680
uniprot id: Q2GC37
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

279238:SARO RS13390
gene id: 279238:SARO_RS13390
uniprot id: Q2G500
names: Similarity
messages: Belongs to the UPF0174 family.

279238:SARO RS13560
gene id: 279238:SARO_RS13560
uniprot id: Q2G4W6
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

279238:SARO RS11375
gene id: 279238:SARO_RS11375
uniprot id: Q2G625
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

279238:SARO RS05420
gene id: 279238:SARO_RS05420
uniprot id: Q2G9E2
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

279238:SARO RS12760
gene id: 279238:SARO_RS12760
uniprot id: Q2G5A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

279238:SARO RS16690
gene id: 279238:SARO_RS16690
uniprot id: Q2G351
names: Similarity
messages: Belongs to the CutA family.

279238:SARO RS11790
gene id: 279238:SARO_RS11790
uniprot id: Q2G5U3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

279238:SARO RS16900
gene id: 279238:SARO_RS16900
uniprot id: Q2G310
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

279238:SARO RS15540
gene id: 279238:SARO_RS15540
uniprot id: Q2G3S8
names: Similarity
messages: Belongs to the peptidase S49 family.

279238:SARO RS09655
gene id: 279238:SARO_RS09655
uniprot id: Q2G707
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

279238:SARO RS04750
gene id: 279238:SARO_RS04750
uniprot id: Q2G9S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

279238:SARO RS06515
gene id: 279238:SARO_RS06515
uniprot id: Q2G8S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

279238:SARO RS02025
gene id: 279238:SARO_RS02025
uniprot id: Q2GBC0
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS12685
gene id: 279238:SARO_RS12685
uniprot id: Q2G5B8
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

279238:SARO RS03200
gene id: 279238:SARO_RS03200
uniprot id: Q2GAN5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

279238:SARO RS19500
gene id: 279238:SARO_RS19500
uniprot id: A4XF73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS06105
gene id: 279238:SARO_RS06105
uniprot id: Q2G907
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

279238:SARO RS00360
gene id: 279238:SARO_RS00360
uniprot id: Q2GCA3
names: Similarity
messages: Belongs to the UPF0235 family.

279238:SARO RS17305
gene id: 279238:SARO_RS17305
uniprot id: A4XDY2
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

279238:SARO RS06330
gene id: 279238:SARO_RS06330
uniprot id: Q2G8W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

279238:SARO RS01645
gene id: 279238:SARO_RS01645
uniprot id: Q2GBJ7
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

279238:SARO RS14830
gene id: 279238:SARO_RS14830
uniprot id: Q2G463
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopC family.
messages: Periplasm

279238:SARO RS18700
gene id: 279238:SARO_RS18700
uniprot id: A4XER4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

279238:SARO RS10135
gene id: 279238:SARO_RS10135
uniprot id: Q2G6R9
names: Subcellular Location Annotation
messages: Cell inner membrane

279238:SARO RS11595
gene id: 279238:SARO_RS11595
uniprot id: Q2G5Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

279238:SARO RS11215
gene id: 279238:SARO_RS11215
uniprot id: Q2G656
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

279238:SARO RS06700
gene id: 279238:SARO_RS06700
uniprot id: Q2G8P0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

279238:SARO RS02065
gene id: 279238:SARO_RS02065
uniprot id: Q2GBB2
names: Similarity
messages: Belongs to the peptidase U62 family.

279238:SARO RS10060
gene id: 279238:SARO_RS10060
uniprot id: Q2G6T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

279238:SARO RS12270
gene id: 279238:SARO_RS12270
uniprot id: Q2G5J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS11365
gene id: 279238:SARO_RS11365
uniprot id: Q2G627
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

279238:SARO RS01675
gene id: 279238:SARO_RS01675
uniprot id: Q2GBJ1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

279238:SARO RS06235
gene id: 279238:SARO_RS06235
uniprot id: Q2G8Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

279238:SARO RS17020
gene id: 279238:SARO_RS17020
uniprot id: A4XDS8
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

279238:SARO RS17970
gene id: 279238:SARO_RS17970
uniprot id: A4XEB8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

279238:SARO RS02420
gene id: 279238:SARO_RS02420
uniprot id: Q2GB43
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS06895
gene id: 279238:SARO_RS06895
uniprot id: Q2G8K4
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

279238:SARO RS11880
gene id: 279238:SARO_RS11880
uniprot id: Q2G5S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

279238:SARO RS06250
gene id: 279238:SARO_RS06250
uniprot id: Q2G8Y0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

279238:SARO RS05695
gene id: 279238:SARO_RS05695
uniprot id: Q2G986
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

279238:SARO RS17105
gene id: 279238:SARO_RS17105
uniprot id: A4XDU4
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

279238:SARO RS17965
gene id: 279238:SARO_RS17965
uniprot id: A4XEB7
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

279238:SARO RS05080
gene id: 279238:SARO_RS05080
uniprot id: Q2G9L1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

279238:SARO RS11405
gene id: 279238:SARO_RS11405
uniprot id: Q2G619
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

279238:SARO RS04895
gene id: 279238:SARO_RS04895
uniprot id: Q2G9P8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

279238:SARO RS06110
gene id: 279238:SARO_RS06110
uniprot id: Q2G906
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

279238:SARO RS05610
gene id: 279238:SARO_RS05610
uniprot id: Q2G9A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

279238:SARO RS04575
gene id: 279238:SARO_RS04575
uniprot id: Q2G9W3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

279238:SARO RS12550
gene id: 279238:SARO_RS12550
uniprot id: Q2G5E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

279238:SARO RS10640
gene id: 279238:SARO_RS10640
uniprot id: Q2G6G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

279238:SARO RS05580
gene id: 279238:SARO_RS05580
uniprot id: Q2G9A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (CcmA) and two transmembrane proteins (CcmB).

279238:SARO RS03555
gene id: 279238:SARO_RS03555
uniprot id: Q2GAG5
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS08810
gene id: 279238:SARO_RS08810
uniprot id: Q2G7H3
names: Similarity
messages: Belongs to the CFA/CMAS family.

279238:SARO RS00385
gene id: 279238:SARO_RS00385
uniprot id: Q2GC98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

279238:SARO RS04885
gene id: 279238:SARO_RS04885
uniprot id: Q2G9Q0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

279238:SARO RS14780
gene id: 279238:SARO_RS14780
uniprot id: Q2G473
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

279238:SARO RS12875
gene id: 279238:SARO_RS12875
uniprot id: Q2G583
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

279238:SARO RS19170
gene id: 279238:SARO_RS19170
uniprot id: A4XF07
names: Similarity
messages: Belongs to the cytochrome P450 family.

279238:SARO RS09185
gene id: 279238:SARO_RS09185
uniprot id: Q2G798
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

279238:SARO RS07775
gene id: 279238:SARO_RS07775
uniprot id: Q2G831
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

279238:SARO RS01380
gene id: 279238:SARO_RS01380
uniprot id: Q2GBQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

279238:SARO RS19940
gene id: 279238:SARO_RS19940
uniprot id: A4XFG1
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

279238:SARO RS19145
gene id: 279238:SARO_RS19145
uniprot id: A4XF02
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

279238:SARO RS08320
gene id: 279238:SARO_RS08320
uniprot id: Q2G7S4
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

279238:SARO RS05130
gene id: 279238:SARO_RS05130
uniprot id: Q2G9K0
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

279238:SARO RS04830
gene id: 279238:SARO_RS04830
uniprot id: Q2G9R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

279238:SARO RS17310
gene id: 279238:SARO_RS17310
uniprot id: A4XDY3
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

279238:SARO RS06415
gene id: 279238:SARO_RS06415
uniprot id: Q2G8U6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

279238:SARO RS19465
gene id: 279238:SARO_RS19465
uniprot id: A4XF67
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

279238:SARO RS15935
gene id: 279238:SARO_RS15935
uniprot id: Q2G3K1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

279238:SARO RS09015
gene id: 279238:SARO_RS09015
uniprot id: Q2G7D2
names: Similarity
messages: Belongs to the DprA/Smf family.

279238:SARO RS11240
gene id: 279238:SARO_RS11240
uniprot id: Q2G652
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

279238:SARO RS06100
gene id: 279238:SARO_RS06100
uniprot id: Q2G908
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

279238:SARO RS09130
gene id: 279238:SARO_RS09130
uniprot id: Q2G7A9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

279238:SARO RS07060
gene id: 279238:SARO_RS07060
uniprot id: Q2G8H1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

279238:SARO RS01885
gene id: 279238:SARO_RS01885
uniprot id: Q2GBE8
names: Similarity
messages: Belongs to the SBNO family.

279238:SARO RS05680
gene id: 279238:SARO_RS05680
uniprot id: Q2G989
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

279238:SARO RS02795
gene id: 279238:SARO_RS02795
uniprot id: Q2GAW6
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS08555
gene id: 279238:SARO_RS08555
uniprot id: Q2G7M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS16145
gene id: 279238:SARO_RS16145
uniprot id: Q2G3F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

279238:SARO RS12405
gene id: 279238:SARO_RS12405
uniprot id: Q2G5H2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

279238:SARO RS05555
gene id: 279238:SARO_RS05555
uniprot id: Q2G9B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

279238:SARO RS01200
gene id: 279238:SARO_RS01200
uniprot id: Q2GBT4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

279238:SARO RS16590
gene id: 279238:SARO_RS16590
uniprot id: Q2G371
names: Subunit
messages: Homotetramer.

279238:SARO RS05670
gene id: 279238:SARO_RS05670
uniprot id: Q2G991
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

279238:SARO RS05915
gene id: 279238:SARO_RS05915
uniprot id: Q2G942
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS11730
gene id: 279238:SARO_RS11730
uniprot id: Q2G5V5
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

279238:SARO RS16760
gene id: 279238:SARO_RS16760
uniprot id: Q2G338
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

279238:SARO RS15055
gene id: 279238:SARO_RS15055
uniprot id: Q2G418
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

279238:SARO RS17150
gene id: 279238:SARO_RS17150
uniprot id: A4XDV3
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

279238:SARO RS04600
gene id: 279238:SARO_RS04600
uniprot id: Q2G9V7
names: Similarity
messages: Belongs to the threonine synthase family.

279238:SARO RS16455
gene id: 279238:SARO_RS16455
uniprot id: Q2G397
names: Similarity
messages: Belongs to the asparagine synthetase family.

279238:SARO RS16830
gene id: 279238:SARO_RS16830
uniprot id: Q2G324
names: Similarity
messages: Belongs to the heat shock protein 70 family.

279238:SARO RS11310
gene id: 279238:SARO_RS11310
uniprot id: Q2G638
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

279238:SARO RS08250
gene id: 279238:SARO_RS08250
uniprot id: Q2G7T8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

279238:SARO RS09230
gene id: 279238:SARO_RS09230
uniprot id: Q2G789
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

279238:SARO RS01490
gene id: 279238:SARO_RS01490
uniprot id: Q2GBM8
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

279238:SARO RS05495
gene id: 279238:SARO_RS05495
uniprot id: Q2G9C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

279238:SARO RS18445
gene id: 279238:SARO_RS18445
uniprot id: A4XEL3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

279238:SARO RS14695
gene id: 279238:SARO_RS14695
uniprot id: Q2G490
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

279238:SARO RS11760
gene id: 279238:SARO_RS11760
uniprot id: Q2G5U9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

279238:SARO RS05990
gene id: 279238:SARO_RS05990
uniprot id: Q2G929
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

279238:SARO RS09480
gene id: 279238:SARO_RS09480
uniprot id: Q2G740
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

279238:SARO RS00520
gene id: 279238:SARO_RS00520
uniprot id: Q2GC70
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

279238:SARO RS19790
gene id: 279238:SARO_RS19790
uniprot id: A4XFD1
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS06905
gene id: 279238:SARO_RS06905
uniprot id: Q2G8K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

279238:SARO RS16680
gene id: 279238:SARO_RS16680
uniprot id: Q2G353
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

279238:SARO RS06560
gene id: 279238:SARO_RS06560
uniprot id: Q2G8R8
names: Similarity
messages: Belongs to the UPF0758 family.

279238:SARO RS04530
gene id: 279238:SARO_RS04530
uniprot id: Q2G9X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

279238:SARO RS18750
gene id: 279238:SARO_RS18750
uniprot id: A4XES4
names: Similarity
messages: Belongs to the hyi family.

279238:SARO RS06600
gene id: 279238:SARO_RS06600
uniprot id: Q2G8R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

279238:SARO RS00575
gene id: 279238:SARO_RS00575
uniprot id: Q2GC59
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

279238:SARO RS15665
gene id: 279238:SARO_RS15665
uniprot id: Q2G3Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS00775
gene id: 279238:SARO_RS00775
uniprot id: Q2GC18
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

279238:SARO RS06680
gene id: 279238:SARO_RS06680
uniprot id: Q2G8P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

279238:SARO RS04940
gene id: 279238:SARO_RS04940
uniprot id: Q2G9N9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

279238:SARO RS16200
gene id: 279238:SARO_RS16200
uniprot id: Q2G3E8
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

279238:SARO RS02125
gene id: 279238:SARO_RS02125
uniprot id: Q2GBA0
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

279238:SARO RS14375
gene id: 279238:SARO_RS14375
uniprot id: Q2G4F3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

279238:SARO RS10810
gene id: 279238:SARO_RS10810
uniprot id: Q2G6D6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

279238:SARO RS18745
gene id: 279238:SARO_RS18745
uniprot id: A4XES3
names: Similarity
messages: Belongs to the Gfa family.

279238:SARO RS02930
gene id: 279238:SARO_RS02930
uniprot id: Q2GAT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

279238:SARO RS05295
gene id: 279238:SARO_RS05295
uniprot id: Q2G9G7
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme may modulate central metabolism.
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

279238:SARO RS01360
gene id: 279238:SARO_RS01360
uniprot id: Q2GBQ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

279238:SARO RS09945
gene id: 279238:SARO_RS09945
uniprot id: Q2G6V4
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

279238:SARO RS06290
gene id: 279238:SARO_RS06290
uniprot id: Q2G8X2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

279238:SARO RS00930
gene id: 279238:SARO_RS00930
uniprot id: Q2GBY7
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

279238:SARO RS03740
gene id: 279238:SARO_RS03740
uniprot id: Q2GAC8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

279238:SARO RS01550
gene id: 279238:SARO_RS01550
uniprot id: Q2GBL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

279238:SARO RS06970
gene id: 279238:SARO_RS06970
uniprot id: Q2G8I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

279238:SARO RS08720
gene id: 279238:SARO_RS08720
uniprot id: Q2G7J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

279238:SARO RS10355
gene id: 279238:SARO_RS10355
uniprot id: Q2G6M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

279238:SARO RS03595
gene id: 279238:SARO_RS03595
uniprot id: Q2GAF7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

279238:SARO RS08805
gene id: 279238:SARO_RS08805
uniprot id: Q2G7H4
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

279238:SARO RS00795
gene id: 279238:SARO_RS00795
uniprot id: Q2GC13
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

279238:SARO RS09060
gene id: 279238:SARO_RS09060
uniprot id: Q2G7C3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

279238:SARO RS14635
gene id: 279238:SARO_RS14635
uniprot id: Q2G4A1
names: Similarity
messages: Belongs to the AHA1 family.

279238:SARO RS07095
gene id: 279238:SARO_RS07095
uniprot id: Q2G8G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

279238:SARO RS17300
gene id: 279238:SARO_RS17300
uniprot id: A4XDY1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

279238:SARO RS14210
gene id: 279238:SARO_RS14210
uniprot id: Q2G4I6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

279238:SARO RS01065
gene id: 279238:SARO_RS01065
uniprot id: Q2GBW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

279238:SARO RS18390
gene id: 279238:SARO_RS18390
uniprot id: A4XEK2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

279238:SARO RS09100
gene id: 279238:SARO_RS09100
uniprot id: Q2G7B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0314 family.
messages: Cell membrane

279238:SARO RS16100
gene id: 279238:SARO_RS16100
uniprot id: Q2G3G8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

279238:SARO RS12075
gene id: 279238:SARO_RS12075
uniprot id: Q2G5N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

279238:SARO RS19305
gene id: 279238:SARO_RS19305
uniprot id: A4XF35
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

279238:SARO RS07040
gene id: 279238:SARO_RS07040
uniprot id: Q2G8H5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

279238:SARO RS11110
gene id: 279238:SARO_RS11110
uniprot id: Q2G677
names: Similarity
messages: Belongs to the SBNO family.

279238:SARO RS01530
gene id: 279238:SARO_RS01530
uniprot id: Q2GBM0
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

279238:SARO RS10770
gene id: 279238:SARO_RS10770
uniprot id: Q2G6E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopC family.
messages: Periplasm

279238:SARO RS01705
gene id: 279238:SARO_RS01705
uniprot id: Q2GBI5
names: Similarity
messages: Belongs to the CobH/CbiC family.

279238:SARO RS02825
gene id: 279238:SARO_RS02825
uniprot id: Q2GAW0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

279238:SARO RS11320
gene id: 279238:SARO_RS11320
uniprot id: Q2G636
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

279238:SARO RS16670
gene id: 279238:SARO_RS16670
uniprot id: Q2G355
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

279238:SARO RS10460
gene id: 279238:SARO_RS10460
uniprot id: Q2G6K5
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

279238:SARO RS17330
gene id: 279238:SARO_RS17330
uniprot id: A4XDY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

279238:SARO RS10420
gene id: 279238:SARO_RS10420
uniprot id: Q2G6L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

279238:SARO RS07050
gene id: 279238:SARO_RS07050
uniprot id: Q2G8H3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

279238:SARO RS10545
gene id: 279238:SARO_RS10545
uniprot id: Q2G6I7
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS15990
gene id: 279238:SARO_RS15990
uniprot id: Q2G3J0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

279238:SARO RS00705
gene id: 279238:SARO_RS00705
uniprot id: Q2GC32
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

279238:SARO RS20000
gene id: 279238:SARO_RS20000
uniprot id: A4XFH3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

279238:SARO RS03380
gene id: 279238:SARO_RS03380
uniprot id: Q2GAJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

279238:SARO RS19270
gene id: 279238:SARO_RS19270
uniprot id: A4XF27
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

279238:SARO RS11710
gene id: 279238:SARO_RS11710
uniprot id: Q2G5V9
names: Similarity
messages: Belongs to the asparagine synthetase family.

279238:SARO RS15800
gene id: 279238:SARO_RS15800
uniprot id: Q2G3M7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

279238:SARO RS02675
gene id: 279238:SARO_RS02675
uniprot id: Q2GAY9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

279238:SARO RS05135
gene id: 279238:SARO_RS05135
uniprot id: Q2G9J9
names: Cofactor
messages: Can also use Mn(2+) ion.

279238:SARO RS11350
gene id: 279238:SARO_RS11350
uniprot id: Q2G630
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

279238:SARO RS01475
gene id: 279238:SARO_RS01475
uniprot id: Q2GBN1
names: Similarity
messages: Belongs to the peptidase U62 family.

279238:SARO RS16320
gene id: 279238:SARO_RS16320
uniprot id: Q2G3C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

279238:SARO RS04975
gene id: 279238:SARO_RS04975
uniprot id: Q2G9N2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

279238:SARO RS15375
gene id: 279238:SARO_RS15375
uniprot id: Q2G3V9
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

279238:SARO RS13250
gene id: 279238:SARO_RS13250
uniprot id: Q2G510
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

279238:SARO RS16610
gene id: 279238:SARO_RS16610
uniprot id: Q2G367
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

279238:SARO RS04305
gene id: 279238:SARO_RS04305
uniprot id: Q2GA18
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

279238:SARO RS14220
gene id: 279238:SARO_RS14220
uniprot id: Q2G4I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS09090
gene id: 279238:SARO_RS09090
uniprot id: Q2G7B7
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

279238:SARO RS04630
gene id: 279238:SARO_RS04630
uniprot id: Q2G9V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

279238:SARO RS03970
gene id: 279238:SARO_RS03970
uniprot id: Q2GA83
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS06855
gene id: 279238:SARO_RS06855
uniprot id: Q2G8L2
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

279238:SARO RS16520
gene id: 279238:SARO_RS16520
uniprot id: Q2G383
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

279238:SARO RS13500
gene id: 279238:SARO_RS13500
uniprot id: Q2G4X8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

279238:SARO RS05625
gene id: 279238:SARO_RS05625
uniprot id: Q2G9A0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

279238:SARO RS09390
gene id: 279238:SARO_RS09390
uniprot id: Q2G758
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

279238:SARO RS19705
gene id: 279238:SARO_RS19705
uniprot id: A4XFB4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

279238:SARO RS03460
gene id: 279238:SARO_RS03460
uniprot id: Q2GAI3
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

279238:SARO RS09005
gene id: 279238:SARO_RS09005
uniprot id: Q2G7D4
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

279238:SARO RS12735
gene id: 279238:SARO_RS12735
uniprot id: Q2G5A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

279238:SARO RS04915
gene id: 279238:SARO_RS04915
uniprot id: Q2G9P4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

279238:SARO RS18130
gene id: 279238:SARO_RS18130
uniprot id: A4XEF0
names: Similarity
messages: Belongs to the thioredoxin family.

279238:SARO RS06495
gene id: 279238:SARO_RS06495
uniprot id: Q2G8T1
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS16950
gene id: 279238:SARO_RS16950
uniprot id: Q2G300
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

279238:SARO RS04795
gene id: 279238:SARO_RS04795
uniprot id: Q2G9R8
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

279238:SARO RS20010
gene id: 279238:SARO_RS20010
uniprot id: A4XFH5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

279238:SARO RS05715
gene id: 279238:SARO_RS05715
uniprot id: Q2G983
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

279238:SARO RS14505
gene id: 279238:SARO_RS14505
uniprot id: Q2G4C7
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

279238:SARO RS04310
gene id: 279238:SARO_RS04310
uniprot id: Q2GA17
names: Similarity
messages: Belongs to the HIBADH-related family.

279238:SARO RS14805
gene id: 279238:SARO_RS14805
uniprot id: Q2G468
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

279238:SARO RS16130
gene id: 279238:SARO_RS16130
uniprot id: Q2G3G2
names: Similarity
messages: Belongs to the glutamate synthase family.

279238:SARO RS20275
gene id: 279238:SARO_RS20275
uniprot id: Q2G4U9
names: Similarity
messages: Belongs to the SCO1/2 family.

279238:SARO RS10700
gene id: 279238:SARO_RS10700
uniprot id: Q2G6F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

279238:SARO RS14725
gene id: 279238:SARO_RS14725
uniprot id: Q2G484
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

279238:SARO RS07230
gene id: 279238:SARO_RS07230
uniprot id: Q2G8D7
names: Similarity
messages: Belongs to the virb1 family.

279238:SARO RS01115
gene id: 279238:SARO_RS01115
uniprot id: Q2GBV2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

279238:SARO RS06690
gene id: 279238:SARO_RS06690
uniprot id: Q2G8P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

279238:SARO RS14360
gene id: 279238:SARO_RS14360
uniprot id: Q2G4F6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

279238:SARO RS01870
gene id: 279238:SARO_RS01870
uniprot id: Q2GBF1
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS06695
gene id: 279238:SARO_RS06695
uniprot id: Q2G8P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

279238:SARO RS03995
gene id: 279238:SARO_RS03995
uniprot id: Q2GA78
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS07155
gene id: 279238:SARO_RS07155
uniprot id: Q2G8F2
names: Similarity
messages: Belongs to the fabD family.

279238:SARO RS12390
gene id: 279238:SARO_RS12390
uniprot id: Q2G5H5
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS09820
gene id: 279238:SARO_RS09820
uniprot id: Q2G6X6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

279238:SARO RS16510
gene id: 279238:SARO_RS16510
uniprot id: Q2G385
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.
messages: Sulfate-activating enzymes, NodP and NodQ, may be physically associated.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

279238:SARO RS05895
gene id: 279238:SARO_RS05895
uniprot id: Q2G946
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

279238:SARO RS16155
gene id: 279238:SARO_RS16155
uniprot id: Q2G3F7
names: Similarity
messages: Belongs to the UPF0311 family.

279238:SARO RS16740
gene id: 279238:SARO_RS16740
uniprot id: Q2G341
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

279238:SARO RS07715
gene id: 279238:SARO_RS07715
uniprot id: Q2G842
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS07695
gene id: 279238:SARO_RS07695
uniprot id: Q2G847
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS00300
gene id: 279238:SARO_RS00300
uniprot id: Q2GCB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

279238:SARO RS17820
gene id: 279238:SARO_RS17820
uniprot id: A4XE88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

279238:SARO RS05190
gene id: 279238:SARO_RS05190
uniprot id: Q2G9I7
names: Similarity
messages: Belongs to the SAICAR synthetase family.

279238:SARO RS14365
gene id: 279238:SARO_RS14365
uniprot id: Q2G4F5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

279238:SARO RS16240
gene id: 279238:SARO_RS16240
uniprot id: Q2G3D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

279238:SARO RS10005
gene id: 279238:SARO_RS10005
uniprot id: Q2G6U3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

279238:SARO RS08940
gene id: 279238:SARO_RS08940
uniprot id: Q2G7E7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

279238:SARO RS06875
gene id: 279238:SARO_RS06875
uniprot id: Q2G8K8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.

279238:SARO RS18915
gene id: 279238:SARO_RS18915
uniprot id: A4XEV7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

279238:SARO RS05385
gene id: 279238:SARO_RS05385
uniprot id: Q2G9E9
names: Similarity
messages: Belongs to the bacterial secretin family.

279238:SARO RS05805
gene id: 279238:SARO_RS05805
uniprot id: Q2G964
names: Similarity
messages: Belongs to the SufE family.

279238:SARO RS11330
gene id: 279238:SARO_RS11330
uniprot id: Q2G634
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

279238:SARO RS04045
gene id: 279238:SARO_RS04045
uniprot id: Q2GA68
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

279238:SARO RS13545
gene id: 279238:SARO_RS13545
uniprot id: Q2G4W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

279238:SARO RS08305
gene id: 279238:SARO_RS08305
uniprot id: Q2G7S7
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

279238:SARO RS06500
gene id: 279238:SARO_RS06500
uniprot id: Q2G8T0
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

279238:SARO RS02600
gene id: 279238:SARO_RS02600
uniprot id: Q2GB06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

279238:SARO RS07855
gene id: 279238:SARO_RS07855
uniprot id: Q2G815
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

279238:SARO RS08460
gene id: 279238:SARO_RS08460
uniprot id: Q2G7P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aromatic amine dehydrogenase light chain family.
messages: Heterotetramer of two light and two heavy chains.
messages: Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin.
messages: Periplasm

279238:SARO RS05265
gene id: 279238:SARO_RS05265
uniprot id: Q2G9H3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

279238:SARO RS14845
gene id: 279238:SARO_RS14845
uniprot id: Q2G460
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

279238:SARO RS11270
gene id: 279238:SARO_RS11270
uniprot id: Q2G646
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

279238:SARO RS02920
gene id: 279238:SARO_RS02920
uniprot id: Q2GAU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

279238:SARO RS13105
gene id: 279238:SARO_RS13105
uniprot id: Q2G538
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

279238:SARO RS14760
gene id: 279238:SARO_RS14760
uniprot id: Q2G477
names: Similarity
messages: Belongs to the BolA/IbaG family.

279238:SARO RS13450
gene id: 279238:SARO_RS13450
uniprot id: Q2G4Y8
names: Similarity
messages: Belongs to the GSP L family.

279238:SARO RS11120
gene id: 279238:SARO_RS11120
uniprot id: Q2G675
names: Similarity
messages: Belongs to the virb1 family.

279238:SARO RS19055
gene id: 279238:SARO_RS19055
uniprot id: A4XEY4
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS07545
gene id: 279238:SARO_RS07545
uniprot id: Q2G877
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

279238:SARO RS08215
gene id: 279238:SARO_RS08215
uniprot id: Q2G7U5
names: Similarity
messages: Belongs to the pirin family.

279238:SARO RS10270
gene id: 279238:SARO_RS10270
uniprot id: Q2G6P2
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS16975
gene id: 279238:SARO_RS16975
uniprot id: A4XDR9
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

279238:SARO RS20015
gene id: 279238:SARO_RS20015
uniprot id: A4XFH6
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

279238:SARO RS01295
gene id: 279238:SARO_RS01295
uniprot id: Q2GBR6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

279238:SARO RS00495
gene id: 279238:SARO_RS00495
uniprot id: Q2GC75
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

279238:SARO RS01085
gene id: 279238:SARO_RS01085
uniprot id: Q2GBV8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

279238:SARO RS11335
gene id: 279238:SARO_RS11335
uniprot id: Q2G633
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

279238:SARO RS06295
gene id: 279238:SARO_RS06295
uniprot id: Q2G8X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

279238:SARO RS07970
gene id: 279238:SARO_RS07970
uniprot id: Q2G7Z3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

279238:SARO RS00295
gene id: 279238:SARO_RS00295
uniprot id: Q2GCB5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

279238:SARO RS13600
gene id: 279238:SARO_RS13600
uniprot id: Q2G4V8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

279238:SARO RS12510
gene id: 279238:SARO_RS12510
uniprot id: Q2G5F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

279238:SARO RS00460
gene id: 279238:SARO_RS00460
uniprot id: Q2GC82
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

279238:SARO RS12730
gene id: 279238:SARO_RS12730
uniprot id: Q2G5A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

279238:SARO RS15440
gene id: 279238:SARO_RS15440
uniprot id: Q2G3U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

279238:SARO RS05880
gene id: 279238:SARO_RS05880
uniprot id: Q2G949
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

279238:SARO RS05875
gene id: 279238:SARO_RS05875
uniprot id: Q2G950
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

279238:SARO RS06805
gene id: 279238:SARO_RS06805
uniprot id: Q2G8M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

279238:SARO RS14800
gene id: 279238:SARO_RS14800
uniprot id: Q2G469
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

279238:SARO RS08715
gene id: 279238:SARO_RS08715
uniprot id: Q2G7J2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

279238:SARO RS03370
gene id: 279238:SARO_RS03370
uniprot id: Q2GAK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

279238:SARO RS08730
gene id: 279238:SARO_RS08730
uniprot id: Q2G7I9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

279238:SARO RS18795
gene id: 279238:SARO_RS18795
uniprot id: A4XET3
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS06610
gene id: 279238:SARO_RS06610
uniprot id: Q2G8Q8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

279238:SARO RS08740
gene id: 279238:SARO_RS08740
uniprot id: Q2G7I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

279238:SARO RS02565
gene id: 279238:SARO_RS02565
uniprot id: Q2GB13
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

279238:SARO RS01415
gene id: 279238:SARO_RS01415
uniprot id: Q2GBP3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

279238:SARO RS00215
gene id: 279238:SARO_RS00215
uniprot id: Q2G2Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

279238:SARO RS00200
gene id: 279238:SARO_RS00200
uniprot id: Q2G2Z5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

279238:SARO RS13360
gene id: 279238:SARO_RS13360
uniprot id: Q2G506
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Mediates the ATP-dependent export of glutathione-conjugated substrates, such as heavy metal-glutathione conjugates. ATP hydrolysis is stimulated by glutathione binding. Protects cells against toxic heavy metal ions, such as silver and mercury ions. May also mediate the transport of glutathione-conjugated aromatic hydrocarbons, such as dinitrobenzene.

279238:SARO RS12885
gene id: 279238:SARO_RS12885
uniprot id: Q2G581
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

279238:SARO RS03795
gene id: 279238:SARO_RS03795
uniprot id: Q2GAB7
names: Similarity
messages: Belongs to the cytochrome P450 family.

279238:SARO RS16095
gene id: 279238:SARO_RS16095
uniprot id: Q2G3G9
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

279238:SARO RS05425
gene id: 279238:SARO_RS05425
uniprot id: Q2G9E1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

279238:SARO RS02820
gene id: 279238:SARO_RS02820
uniprot id: Q2GAW1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

279238:SARO RS10200
gene id: 279238:SARO_RS10200
uniprot id: Q2G6Q6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

279238:SARO RS05645
gene id: 279238:SARO_RS05645
uniprot id: Q2G996
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS04945
gene id: 279238:SARO_RS04945
uniprot id: Q2G9N8
names: Similarity
messages: Belongs to the peptidase M16 family.

279238:SARO RS15930
gene id: 279238:SARO_RS15930
uniprot id: Q2G3K2
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS04620
gene id: 279238:SARO_RS04620
uniprot id: Q2G9V3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

279238:SARO RS00735
gene id: 279238:SARO_RS00735
uniprot id: Q2GC26
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

279238:SARO RS19810
gene id: 279238:SARO_RS19810
uniprot id: A4XFD5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

279238:SARO RS07055
gene id: 279238:SARO_RS07055
uniprot id: Q2G8H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

279238:SARO RS09385
gene id: 279238:SARO_RS09385
uniprot id: Q2G759
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

279238:SARO RS12200
gene id: 279238:SARO_RS12200
uniprot id: Q2G5L3
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

279238:SARO RS16905
gene id: 279238:SARO_RS16905
uniprot id: Q2G309
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

279238:SARO RS08445
gene id: 279238:SARO_RS08445
uniprot id: Q2G7P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic amine dehydrogenase heavy chain family.
messages: Periplasm

279238:SARO RS08825
gene id: 279238:SARO_RS08825
uniprot id: Q2G7H0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

279238:SARO RS08595
gene id: 279238:SARO_RS08595
uniprot id: Q2G7L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

279238:SARO RS01465
gene id: 279238:SARO_RS01465
uniprot id: Q2GBN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

279238:SARO RS04675
gene id: 279238:SARO_RS04675
uniprot id: Q2G9U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

279238:SARO RS00020
gene id: 279238:SARO_RS00020
uniprot id: Q2GCF7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

279238:SARO RS04905
gene id: 279238:SARO_RS04905
uniprot id: Q2G9P6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

279238:SARO RS02180
gene id: 279238:SARO_RS02180
uniprot id: Q2GB90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

279238:SARO RS14325
gene id: 279238:SARO_RS14325
uniprot id: Q2G4G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

279238:SARO RS11015
gene id: 279238:SARO_RS11015
uniprot id: Q2G694
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

279238:SARO RS14190
gene id: 279238:SARO_RS14190
uniprot id: Q2G4J0
names: Function
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

279238:SARO RS12025
gene id: 279238:SARO_RS12025
uniprot id: Q2G5P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

279238:SARO RS14810
gene id: 279238:SARO_RS14810
uniprot id: Q2G467
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

279238:SARO RS12465
gene id: 279238:SARO_RS12465
uniprot id: Q2G5G0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

279238:SARO RS17045
gene id: 279238:SARO_RS17045
uniprot id: A4XDT2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

279238:SARO RS16720
gene id: 279238:SARO_RS16720
uniprot id: Q2G345
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

279238:SARO RS14380
gene id: 279238:SARO_RS14380
uniprot id: Q2G4F2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

279238:SARO RS04495
gene id: 279238:SARO_RS04495
uniprot id: Q2G9X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

279238:SARO RS02415
gene id: 279238:SARO_RS02415
uniprot id: Q2GB44
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

279238:SARO RS12205
gene id: 279238:SARO_RS12205
uniprot id: Q2G5L2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

279238:SARO RS01950
gene id: 279238:SARO_RS01950
uniprot id: Q2GBD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

279238:SARO RS16175
gene id: 279238:SARO_RS16175
uniprot id: Q2G3F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

279238:SARO RS16065
gene id: 279238:SARO_RS16065
uniprot id: Q2G3H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

279238:SARO RS07525
gene id: 279238:SARO_RS07525
uniprot id: Q2G881
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

279238:SARO RS06685
gene id: 279238:SARO_RS06685
uniprot id: Q2G8P3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

279238:SARO RS18645
gene id: 279238:SARO_RS18645
uniprot id: A4XEQ3
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

279238:SARO RS12430
gene id: 279238:SARO_RS12430
uniprot id: Q2G5G7
names: Similarity
messages: Belongs to the sulfatase family.

279238:SARO RS14680
gene id: 279238:SARO_RS14680
uniprot id: Q2G492
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

279238:SARO RS12750
gene id: 279238:SARO_RS12750
uniprot id: Q2G5A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

279238:SARO RS16840
gene id: 279238:SARO_RS16840
uniprot id: Q2G322
names: Similarity
messages: Belongs to the phosphohexose mutase family.

279238:SARO RS19590
gene id: 279238:SARO_RS19590
uniprot id: A4XF91
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

279238:SARO RS14410
gene id: 279238:SARO_RS14410
uniprot id: Q2G4E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

279238:SARO RS01060
gene id: 279238:SARO_RS01060
uniprot id: Q2GBW3
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

279238:SARO RS10485
gene id: 279238:SARO_RS10485
uniprot id: Q2G6K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

279238:SARO RS09600
gene id: 279238:SARO_RS09600
uniprot id: Q2G718
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

279238:SARO RS09170
gene id: 279238:SARO_RS09170
uniprot id: Q2G7A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

279238:SARO RS11545
gene id: 279238:SARO_RS11545
uniprot id: Q2G5Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

279238:SARO RS05720
gene id: 279238:SARO_RS05720
uniprot id: Q2G982
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

279238:SARO RS12400
gene id: 279238:SARO_RS12400
uniprot id: Q2G5H3
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

279238:SARO RS08970
gene id: 279238:SARO_RS08970
uniprot id: Q2G7E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

279238:SARO RS04490
gene id: 279238:SARO_RS04490
uniprot id: Q2G9Y0
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

279238:SARO RS04085
gene id: 279238:SARO_RS04085
uniprot id: Q2GA60
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

279238:SARO RS01230
gene id: 279238:SARO_RS01230
uniprot id: Q2GBS9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

279238:SARO RS19975
gene id: 279238:SARO_RS19975
uniprot id: A4XFG8
names: Function
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.

279238:SARO RS20145
gene id: 279238:SARO_RS20145
uniprot id: Q2G9S6
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

279238:SARO RS11620
gene id: 279238:SARO_RS11620
uniprot id: Q2G5X8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

279238:SARO RS06505
gene id: 279238:SARO_RS06505
uniprot id: Q2G8S9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

279238:SARO RS15810
gene id: 279238:SARO_RS15810
uniprot id: Q2G3M5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

279238:SARO RS11070
gene id: 279238:SARO_RS11070
uniprot id: Q2G684
names: Similarity
messages: Belongs to the DprA/Smf family.

279238:SARO RS05335
gene id: 279238:SARO_RS05335
uniprot id: Q2G9F9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

279238:SARO RS02665
gene id: 279238:SARO_RS02665
uniprot id: Q2GAZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS06915
gene id: 279238:SARO_RS06915
uniprot id: Q2G8K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

279238:SARO RS19930
gene id: 279238:SARO_RS19930
uniprot id: A4XFF9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

279238:SARO RS04740
gene id: 279238:SARO_RS04740
uniprot id: Q2G9S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).
messages: Homodimer or monomer when oxidized or reduced, respectively.
messages: chloroplast

279238:SARO RS04055
gene id: 279238:SARO_RS04055
uniprot id: Q2GA65
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

279238:SARO RS15720
gene id: 279238:SARO_RS15720
uniprot id: Q2G3P3
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

279238:SARO RS05835
gene id: 279238:SARO_RS05835
uniprot id: Q2G958
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

279238:SARO RS06320
gene id: 279238:SARO_RS06320
uniprot id: Q2G8W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

279238:SARO RS17100
gene id: 279238:SARO_RS17100
uniprot id: A4XDU3
names: Similarity
messages: Belongs to the GST superfamily.

279238:SARO RS07390
gene id: 279238:SARO_RS07390
uniprot id: Q2G8A7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

279238:SARO RS01595
gene id: 279238:SARO_RS01595
uniprot id: Q2GBK7
names: Similarity
messages: Belongs to the GSP E family.

279238:SARO RS00370
gene id: 279238:SARO_RS00370
uniprot id: Q2GCA1
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

279238:SARO RS10665
gene id: 279238:SARO_RS10665
uniprot id: Q2G6G3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

279238:SARO RS13160
gene id: 279238:SARO_RS13160
uniprot id: Q2G527
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

279238:SARO RS17420
gene id: 279238:SARO_RS17420
uniprot id: A4XE07
names: Similarity
messages: Belongs to the ParB family.

279238:SARO RS10430
gene id: 279238:SARO_RS10430
uniprot id: Q2G6L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

279238:SARO RS03600
gene id: 279238:SARO_RS03600
uniprot id: Q2GAF6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

279238:SARO RS02695
gene id: 279238:SARO_RS02695
uniprot id: Q2GAY5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

279238:SARO RS14895
gene id: 279238:SARO_RS14895
uniprot id: Q2G450
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

279238:SARO RS02705
gene id: 279238:SARO_RS02705
uniprot id: Q2GAY3
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

279238:SARO RS13055
gene id: 279238:SARO_RS13055
uniprot id: Q2G547
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS19495
gene id: 279238:SARO_RS19495
uniprot id: A4XF72
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS05465
gene id: 279238:SARO_RS05465
uniprot id: Q2G9D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

279238:SARO RS05435
gene id: 279238:SARO_RS05435
uniprot id: Q2G9D9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

279238:SARO RS13530
gene id: 279238:SARO_RS13530
uniprot id: Q2G4X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

279238:SARO RS08005
gene id: 279238:SARO_RS08005
uniprot id: Q2G7Y6
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS08785
gene id: 279238:SARO_RS08785
uniprot id: Q2G7H8
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

279238:SARO RS05775
gene id: 279238:SARO_RS05775
uniprot id: Q2G970
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS12425
gene id: 279238:SARO_RS12425
uniprot id: Q2G5G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS02095
gene id: 279238:SARO_RS02095
uniprot id: Q2GBA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

279238:SARO RS00785
gene id: 279238:SARO_RS00785
uniprot id: Q2GC15
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

279238:SARO RS16945
gene id: 279238:SARO_RS16945
uniprot id: Q2G301
names: Similarity
messages: Belongs to the cytochrome P450 family.

279238:SARO RS09235
gene id: 279238:SARO_RS09235
uniprot id: Q2G788
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

279238:SARO RS07185
gene id: 279238:SARO_RS07185
uniprot id: Q2G8E6
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

279238:SARO RS00965
gene id: 279238:SARO_RS00965
uniprot id: Q2GBY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

279238:SARO RS00995
gene id: 279238:SARO_RS00995
uniprot id: Q2GBX5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

279238:SARO RS03960
gene id: 279238:SARO_RS03960
uniprot id: Q2GA85
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

279238:SARO RS17010
gene id: 279238:SARO_RS17010
uniprot id: A4XDS6
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

279238:SARO RS00530
gene id: 279238:SARO_RS00530
uniprot id: Q2GC68
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

279238:SARO RS12645
gene id: 279238:SARO_RS12645
uniprot id: Q2G5C6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

279238:SARO RS16755
gene id: 279238:SARO_RS16755
uniprot id: Q2G339
names: Similarity
messages: Belongs to the YggT family.

279238:SARO RS00145
gene id: 279238:SARO_RS00145
uniprot id: Q2GCD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

279238:SARO RS16985
gene id: 279238:SARO_RS16985
uniprot id: A4XDS1
names: Similarity
messages: Belongs to the DapA family.

279238:SARO RS10470
gene id: 279238:SARO_RS10470
uniprot id: Q2G6K3
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

279238:SARO RS02970
gene id: 279238:SARO_RS02970
uniprot id: Q2GAT0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

279238:SARO RS02890
gene id: 279238:SARO_RS02890
uniprot id: Q2GAU7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

279238:SARO RS19730
gene id: 279238:SARO_RS19730
uniprot id: A4XFB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS16735
gene id: 279238:SARO_RS16735
uniprot id: Q2G342
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

279238:SARO RS05525
gene id: 279238:SARO_RS05525
uniprot id: Q2G9C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

279238:SARO RS05885
gene id: 279238:SARO_RS05885
uniprot id: Q2G948
names: Function
names: Subunit
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

279238:SARO RS00720
gene id: 279238:SARO_RS00720
uniprot id: Q2GC29
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

279238:SARO RS00060
gene id: 279238:SARO_RS00060
uniprot id: Q2GCE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

279238:SARO RS14335
gene id: 279238:SARO_RS14335
uniprot id: Q2G4G1
names: Similarity
messages: Belongs to the peptidase M16 family.

279238:SARO RS11535
gene id: 279238:SARO_RS11535
uniprot id: Q2G5Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

279238:SARO RS08115
gene id: 279238:SARO_RS08115
uniprot id: Q2G7W4
names: Subcellular Location Annotation
messages: Secreted

279238:SARO RS10720
gene id: 279238:SARO_RS10720
uniprot id: Q2G6F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

279238:SARO RS17090
gene id: 279238:SARO_RS17090
uniprot id: A4XDU1
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

279238:SARO RS07165
gene id: 279238:SARO_RS07165
uniprot id: Q2G8F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

279238:SARO RS04580
gene id: 279238:SARO_RS04580
uniprot id: Q2G9W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

279238:SARO RS09435
gene id: 279238:SARO_RS09435
uniprot id: Q2G749
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

279238:SARO RS08735
gene id: 279238:SARO_RS08735
uniprot id: Q2G7I8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

279238:SARO RS00675
gene id: 279238:SARO_RS00675
uniprot id: Q2GC38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

279238:SARO RS01660
gene id: 279238:SARO_RS01660
uniprot id: Q2GBJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

279238:SARO RS01955
gene id: 279238:SARO_RS01955
uniprot id: Q2GBD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

279238:SARO RS01445
gene id: 279238:SARO_RS01445
uniprot id: Q2GBN7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

279238:SARO RS14660
gene id: 279238:SARO_RS14660
uniprot id: Q2G496
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

279238:SARO RS04990
gene id: 279238:SARO_RS04990
uniprot id: Q2G9M9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

279238:SARO RS12300
gene id: 279238:SARO_RS12300
uniprot id: Q2G5J3
names: Function
names: Similarity
messages: Belongs to the aldo/keto reductase family.
messages: Part of the alkanesulfonate monooxygenase (sulfo-ASMO) pathway, a D-sulfoquinovose degradation pathway that enables the complete utilization of all carbons within sulfoquinovose (SQ) with concomitant production of inorganic sulfite (Ref.2). Catalyzes the NADP-dependent reduction of 6-dehydro-D-glucose to D-glucose (Ref.2). Can also catalyze the reversible reaction, the formation of 6-dehydro-D-glucose from D-glucose in the presence of NADP(+) (Ref.2).

279238:SARO RS04720
gene id: 279238:SARO_RS04720
uniprot id: Q2G9T3
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS18905
gene id: 279238:SARO_RS18905
uniprot id: A4XEV5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

279238:SARO RS19970
gene id: 279238:SARO_RS19970
uniprot id: A4XFG7
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

279238:SARO RS04670
gene id: 279238:SARO_RS04670
uniprot id: Q2G9U3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

279238:SARO RS05235
gene id: 279238:SARO_RS05235
uniprot id: Q2G9H8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

279238:SARO RS06095
gene id: 279238:SARO_RS06095
uniprot id: Q2G909
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

279238:SARO RS02290
gene id: 279238:SARO_RS02290
uniprot id: Q2G3H0
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

279238:SARO RS15920
gene id: 279238:SARO_RS15920
uniprot id: Q2G3K4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

279238:SARO RS13190
gene id: 279238:SARO_RS13190
uniprot id: Q2G521
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

279238:SARO RS11585
gene id: 279238:SARO_RS11585
uniprot id: Q2G5Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

279238:SARO RS13520
gene id: 279238:SARO_RS13520
uniprot id: Q2G4X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

279238:SARO RS16730
gene id: 279238:SARO_RS16730
uniprot id: Q2G343
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

279238:SARO RS17620
gene id: 279238:SARO_RS17620
uniprot id: A4XE48
names: Similarity
messages: Belongs to the ros/MucR family.

279238:SARO RS05500
gene id: 279238:SARO_RS05500
uniprot id: Q2G9C6
names: Subcellular Location Annotation
messages: Cell outer membrane

279238:SARO RS19530
gene id: 279238:SARO_RS19530
uniprot id: A4XF79
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

279238:SARO RS07960
gene id: 279238:SARO_RS07960
uniprot id: Q2G7Z5
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS16650
gene id: 279238:SARO_RS16650
uniprot id: Q2G359
names: Similarity
messages: Belongs to the ArsC family.

279238:SARO RS09955
gene id: 279238:SARO_RS09955
uniprot id: Q2G6V2
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

279238:SARO RS10380
gene id: 279238:SARO_RS10380
uniprot id: Q2G6M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

279238:SARO RS03410
gene id: 279238:SARO_RS03410
uniprot id: Q2GAJ3
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

279238:SARO RS16540
gene id: 279238:SARO_RS16540
uniprot id: Q2G379
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

279238:SARO RS05035
gene id: 279238:SARO_RS05035
uniprot id: Q2G9M0
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

279238:SARO RS18785
gene id: 279238:SARO_RS18785
uniprot id: A4XET1
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

279238:SARO RS05740
gene id: 279238:SARO_RS05740
uniprot id: Q2G978
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS06355
gene id: 279238:SARO_RS06355
uniprot id: Q2G8V9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

279238:SARO RS19655
gene id: 279238:SARO_RS19655
uniprot id: A4XFA4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

279238:SARO RS18160
gene id: 279238:SARO_RS18160
uniprot id: A4XEF6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

279238:SARO RS17065
gene id: 279238:SARO_RS17065
uniprot id: A4XDT6
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

279238:SARO RS18695
gene id: 279238:SARO_RS18695
uniprot id: A4XER3
names: Similarity
messages: Belongs to the hyi family.

279238:SARO RS12480
gene id: 279238:SARO_RS12480
uniprot id: Q2G5F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

279238:SARO RS06885
gene id: 279238:SARO_RS06885
uniprot id: Q2G8K6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

279238:SARO RS10145
gene id: 279238:SARO_RS10145
uniprot id: Q2G6R7
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

279238:SARO RS17910
gene id: 279238:SARO_RS17910
uniprot id: A4XEA6
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

279238:SARO RS10375
gene id: 279238:SARO_RS10375
uniprot id: Q2G6M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

279238:SARO RS06140
gene id: 279238:SARO_RS06140
uniprot id: Q2G900
names: Similarity
messages: Belongs to the thioesterase PaaI family.

279238:SARO RS00055
gene id: 279238:SARO_RS00055
uniprot id: Q2GCF0
names: Similarity
messages: Belongs to the ArsC family.

279238:SARO RS09250
gene id: 279238:SARO_RS09250
uniprot id: Q2G785
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

279238:SARO RS03935
gene id: 279238:SARO_RS03935
uniprot id: Q2GA89
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

279238:SARO RS02285
gene id: 279238:SARO_RS02285
uniprot id: Q2G3G9
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

279238:SARO RS03965
gene id: 279238:SARO_RS03965
uniprot id: Q2GA84
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

279238:SARO RS14150
gene id: 279238:SARO_RS14150
uniprot id: Q2G4J8
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

279238:SARO RS19625
gene id: 279238:SARO_RS19625
uniprot id: A4XF98
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

279238:SARO RS11560
gene id: 279238:SARO_RS11560
uniprot id: Q2G5Z0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

279238:SARO RS06350
gene id: 279238:SARO_RS06350
uniprot id: Q2G8W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

279238:SARO RS00625
gene id: 279238:SARO_RS00625
uniprot id: Q2GC48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

279238:SARO RS01095
gene id: 279238:SARO_RS01095
uniprot id: Q2GBV6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

279238:SARO RS00250
gene id: 279238:SARO_RS00250
uniprot id: Q2GCC4
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS11255
gene id: 279238:SARO_RS11255
uniprot id: Q2G649
names: Similarity
messages: Belongs to the UPF0311 family.

279238:SARO RS14880
gene id: 279238:SARO_RS14880
uniprot id: Q2G453
names: Function
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Has multiple catalytic activities. Apart from catalyzing the oxidation of (+)-tartrate to oxaloglycolate, also converts meso-tartrate to D-glycerate and catalyzes the oxidative decarboxylation of D-malate to pyruvate.

279238:SARO RS02085
gene id: 279238:SARO_RS02085
uniprot id: Q2GBA8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

279238:SARO RS02585
gene id: 279238:SARO_RS02585
uniprot id: Q2GB09
names: Subcellular Location Annotation
messages: Cytoplasm

279238:SARO RS09500
gene id: 279238:SARO_RS09500
uniprot id: Q2G736
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

279238:SARO RS06090
gene id: 279238:SARO_RS06090
uniprot id: Q2G910
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

279238:SARO RS10570
gene id: 279238:SARO_RS10570
uniprot id: Q2G6I2
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS08265
gene id: 279238:SARO_RS08265
uniprot id: Q2G7T5
names: Similarity
messages: Belongs to the cytochrome P450 family.

279238:SARO RS10130
gene id: 279238:SARO_RS10130
uniprot id: Q2G6S0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

279238:SARO RS06260
gene id: 279238:SARO_RS06260
uniprot id: Q2G8X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

279238:SARO RS19225
gene id: 279238:SARO_RS19225
uniprot id: A4XF18
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS01005
gene id: 279238:SARO_RS01005
uniprot id: Q2GBX3
names: Similarity
messages: Belongs to the HesB/IscA family.

279238:SARO RS04250
gene id: 279238:SARO_RS04250
uniprot id: Q2GA28
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

279238:SARO RS15400
gene id: 279238:SARO_RS15400
uniprot id: Q2G3V4
names: Caution
names: Similarity
messages: Belongs to the peptidase S8 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

279238:SARO RS02860
gene id: 279238:SARO_RS02860
uniprot id: Q2GAV3
names: Similarity
messages: Belongs to the AAA ATPase family.

279238:SARO RS02115
gene id: 279238:SARO_RS02115
uniprot id: Q2GBA2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

279238:SARO RS08690
gene id: 279238:SARO_RS08690
uniprot id: Q2G7J7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

279238:SARO RS00660
gene id: 279238:SARO_RS00660
uniprot id: Q2GC41
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

279238:SARO RS18080
gene id: 279238:SARO_RS18080
uniprot id: A4XEE0
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

279238:SARO RS09195
gene id: 279238:SARO_RS09195
uniprot id: Q2G796
names: Similarity
messages: Belongs to the peptidase S8 family.

279238:SARO RS00115
gene id: 279238:SARO_RS00115
uniprot id: Q2GCD8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

279238:SARO RS07090
gene id: 279238:SARO_RS07090
uniprot id: Q2G8G5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

279238:SARO RS11540
gene id: 279238:SARO_RS11540
uniprot id: Q2G5Z4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

279238:SARO RS19130
gene id: 279238:SARO_RS19130
uniprot id: A4XEZ9
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

279238:SARO RS06005
gene id: 279238:SARO_RS06005
uniprot id: Q2G926
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

279238:SARO RS15450
gene id: 279238:SARO_RS15450
uniprot id: Q2G3U3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

279238:SARO RS16305
gene id: 279238:SARO_RS16305
uniprot id: Q2G3C6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

279238:SARO RS02615
gene id: 279238:SARO_RS02615
uniprot id: Q2GB03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS12980
gene id: 279238:SARO_RS12980
uniprot id: Q2G562
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.
messages: Membrane

279238:SARO RS08755
gene id: 279238:SARO_RS08755
uniprot id: Q2G7I4
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS14530
gene id: 279238:SARO_RS14530
uniprot id: Q2G4C2
names: Similarity
messages: Belongs to the GST superfamily.

279238:SARO RS06960
gene id: 279238:SARO_RS06960
uniprot id: Q2G8J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

279238:SARO RS03440
gene id: 279238:SARO_RS03440
uniprot id: Q2GAI7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

279238:SARO RS02230
gene id: 279238:SARO_RS02230
uniprot id: Q2GB80
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

279238:SARO RS06305
gene id: 279238:SARO_RS06305
uniprot id: Q2G8W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

279238:SARO RS18970
gene id: 279238:SARO_RS18970
uniprot id: A4XEW8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

279238:SARO RS05560
gene id: 279238:SARO_RS05560
uniprot id: Q2G9B3
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

279238:SARO RS13000
gene id: 279238:SARO_RS13000
uniprot id: Q2G558
names: Similarity
messages: Belongs to the OmpW/AlkL family.

279238:SARO RS05175
gene id: 279238:SARO_RS05175
uniprot id: Q2G9J0
names: Similarity
messages: Belongs to the peptidase M16 family.

279238:SARO RS10585
gene id: 279238:SARO_RS10585
uniprot id: Q2G6H9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

279238:SARO RS02710
gene id: 279238:SARO_RS02710
uniprot id: Q2GAY2
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

279238:SARO RS03780
gene id: 279238:SARO_RS03780
uniprot id: Q2GAC0
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

279238:SARO RS07315
gene id: 279238:SARO_RS07315
uniprot id: Q2G8C2
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

279238:SARO RS05210
gene id: 279238:SARO_RS05210
uniprot id: Q2G9I3
names: Function
names: Subunit
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

279238:SARO RS08700
gene id: 279238:SARO_RS08700
uniprot id: Q2G7J5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

279238:SARO RS14060
gene id: 279238:SARO_RS14060
uniprot id: Q2G4L6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

279238:SARO RS07575
gene id: 279238:SARO_RS07575
uniprot id: Q2G870
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

279238:SARO RS06335
gene id: 279238:SARO_RS06335
uniprot id: Q2G8W3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

279238:SARO RS15525
gene id: 279238:SARO_RS15525
uniprot id: Q2G3S9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

279238:SARO RS05545
gene id: 279238:SARO_RS05545
uniprot id: Q2G9B6
names: Similarity
messages: Belongs to the peptidase M17 family.

279238:SARO RS04825
gene id: 279238:SARO_RS04825
uniprot id: Q2G9R2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

279238:SARO RS01560
gene id: 279238:SARO_RS01560
uniprot id: Q2GBL4
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS11610
gene id: 279238:SARO_RS11610
uniprot id: Q2G5Y0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

279238:SARO RS04125
gene id: 279238:SARO_RS04125
uniprot id: Q2GA52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

279238:SARO RS16060
gene id: 279238:SARO_RS16060
uniprot id: Q2G3H6
names: Similarity
messages: Belongs to the cytochrome P450 family.

279238:SARO RS09515
gene id: 279238:SARO_RS09515
uniprot id: Q2G733
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

279238:SARO RS16795
gene id: 279238:SARO_RS16795
uniprot id: Q2G331
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

279238:SARO RS07235
gene id: 279238:SARO_RS07235
uniprot id: Q2G8D6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

279238:SARO RS06540
gene id: 279238:SARO_RS06540
uniprot id: Q2G8S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

279238:SARO RS13455
gene id: 279238:SARO_RS13455
uniprot id: Q2G4Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

279238:SARO RS09270
gene id: 279238:SARO_RS09270
uniprot id: Q2G781
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

279238:SARO RS00070
gene id: 279238:SARO_RS00070
uniprot id: Q2GCE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

279238:SARO RS19220
gene id: 279238:SARO_RS19220
uniprot id: A4XF17
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

279238:SARO RS07015
gene id: 279238:SARO_RS07015
uniprot id: Q2G8I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

279238:SARO RS03420
gene id: 279238:SARO_RS03420
uniprot id: Q2GAJ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

279238:SARO RS04470
gene id: 279238:SARO_RS04470
uniprot id: Q2G9Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

279238:SARO RS07160
gene id: 279238:SARO_RS07160
uniprot id: Q2G8F1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

279238:SARO RS12315
gene id: 279238:SARO_RS12315
uniprot id: Q2G5J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS01720
gene id: 279238:SARO_RS01720
uniprot id: Q2GBI2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

279238:SARO RS09605
gene id: 279238:SARO_RS09605
uniprot id: Q2G717
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

279238:SARO RS00560
gene id: 279238:SARO_RS00560
uniprot id: Q2GC62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

279238:SARO RS11690
gene id: 279238:SARO_RS11690
uniprot id: Q2G5W4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

279238:SARO RS12770
gene id: 279238:SARO_RS12770
uniprot id: Q2G5A1
names: Subunit
messages: Homodimer.

279238:SARO RS15545
gene id: 279238:SARO_RS15545
uniprot id: Q2G3S7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

279238:SARO RS03415
gene id: 279238:SARO_RS03415
uniprot id: Q2GAJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

279238:SARO RS19685
gene id: 279238:SARO_RS19685
uniprot id: A4XFB0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

279238:SARO RS12610
gene id: 279238:SARO_RS12610
uniprot id: Q2G5D3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

279238:SARO RS09570
gene id: 279238:SARO_RS09570
uniprot id: Q2G724
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

279238:SARO RS10195
gene id: 279238:SARO_RS10195
uniprot id: Q2G6Q7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

279238:SARO RS04645
gene id: 279238:SARO_RS04645
uniprot id: Q2G9U8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

279238:SARO RS09755
gene id: 279238:SARO_RS09755
uniprot id: Q2G6Y8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

279238:SARO RS06965
gene id: 279238:SARO_RS06965
uniprot id: Q2G8J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

279238:SARO RS05585
gene id: 279238:SARO_RS05585
uniprot id: Q2G9A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

279238:SARO RS09110
gene id: 279238:SARO_RS09110
uniprot id: Q2G7B3
names: Similarity
messages: Belongs to the FMO family.

279238:SARO RS10710
gene id: 279238:SARO_RS10710
uniprot id: Q2G6F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

279238:SARO RS02965
gene id: 279238:SARO_RS02965
uniprot id: Q2GAT1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

279238:SARO RS18805
gene id: 279238:SARO_RS18805
uniprot id: A4XET5
names: Similarity
messages: Belongs to the FrmR/RcnR family.

279238:SARO RS12320
gene id: 279238:SARO_RS12320
uniprot id: Q2G5I9
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS05365
gene id: 279238:SARO_RS05365
uniprot id: Q2G9F3
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS13415
gene id: 279238:SARO_RS13415
uniprot id: Q2G4Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

279238:SARO RS00085
gene id: 279238:SARO_RS00085
uniprot id: Q2GCE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

279238:SARO RS08295
gene id: 279238:SARO_RS08295
uniprot id: Q2G7S9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

279238:SARO RS00915
gene id: 279238:SARO_RS00915
uniprot id: Q2GBZ0
names: Similarity
messages: Belongs to the peptidase S9C family.

279238:SARO RS10090
gene id: 279238:SARO_RS10090
uniprot id: Q2G6S7
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

279238:SARO RS17920
gene id: 279238:SARO_RS17920
uniprot id: A4XEA8
names: Similarity
messages: Belongs to the PrpD family.

279238:SARO RS16705
gene id: 279238:SARO_RS16705
uniprot id: Q2G348
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

279238:SARO RS14685
gene id: 279238:SARO_RS14685
uniprot id: Q2G491
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

279238:SARO RS19260
gene id: 279238:SARO_RS19260
uniprot id: A4XEM2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

279238:SARO RS10155
gene id: 279238:SARO_RS10155
uniprot id: Q2G6R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

279238:SARO RS03675
gene id: 279238:SARO_RS03675
uniprot id: Q2GAE1
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

279238:SARO RS06120
gene id: 279238:SARO_RS06120
uniprot id: Q2G904
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

279238:SARO RS09825
gene id: 279238:SARO_RS09825
uniprot id: Q2G6X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

279238:SARO RS10560
gene id: 279238:SARO_RS10560
uniprot id: Q2G6I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

279238:SARO RS01580
gene id: 279238:SARO_RS01580
uniprot id: Q2GBL0
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

279238:SARO RS04215
gene id: 279238:SARO_RS04215
uniprot id: Q2GA35
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS01965
gene id: 279238:SARO_RS01965
uniprot id: Q2GBD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

279238:SARO RS18875
gene id: 279238:SARO_RS18875
uniprot id: A4XEU9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

279238:SARO RS03605
gene id: 279238:SARO_RS03605
uniprot id: Q2GAF5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

279238:SARO RS17595
gene id: 279238:SARO_RS17595
uniprot id: A4XE42
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

279238:SARO RS06595
gene id: 279238:SARO_RS06595
uniprot id: Q2G8R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

279238:SARO RS13195
gene id: 279238:SARO_RS13195
uniprot id: Q2G520
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

279238:SARO RS00630
gene id: 279238:SARO_RS00630
uniprot id: Q2GC47
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

279238:SARO RS19850
gene id: 279238:SARO_RS19850
uniprot id: A4XFE3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

279238:SARO RS11490
gene id: 279238:SARO_RS11490
uniprot id: Q2G604
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

279238:SARO RS12455
gene id: 279238:SARO_RS12455
uniprot id: Q2G5G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell inner membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

279238:SARO RS17005
gene id: 279238:SARO_RS17005
uniprot id: A4XDS5
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

279238:SARO RS08330
gene id: 279238:SARO_RS08330
uniprot id: Q2G7S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS08670
gene id: 279238:SARO_RS08670
uniprot id: Q2G7K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

279238:SARO RS13580
gene id: 279238:SARO_RS13580
uniprot id: Q2G4W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

279238:SARO RS11130
gene id: 279238:SARO_RS11130
uniprot id: Q2G673
names: Similarity
messages: Belongs to the AHA1 family.

279238:SARO RS09510
gene id: 279238:SARO_RS09510
uniprot id: Q2G734
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

279238:SARO RS18055
gene id: 279238:SARO_RS18055
uniprot id: A4XED5
names: Similarity
messages: Belongs to the sulfatase family.

279238:SARO RS06045
gene id: 279238:SARO_RS06045
uniprot id: Q2G919
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS14770
gene id: 279238:SARO_RS14770
uniprot id: Q2G475
names: Similarity
messages: Belongs to the pirin family.

279238:SARO RS08220
gene id: 279238:SARO_RS08220
uniprot id: Q2G7U4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

279238:SARO RS00270
gene id: 279238:SARO_RS00270
uniprot id: Q2GCC0
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS12655
gene id: 279238:SARO_RS12655
uniprot id: Q2G5C4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

279238:SARO RS11265
gene id: 279238:SARO_RS11265
uniprot id: Q2G647
names: Similarity
messages: Belongs to the LacAB/RpiB family.

279238:SARO RS17555
gene id: 279238:SARO_RS17555
uniprot id: A4XE34
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

279238:SARO RS07895
gene id: 279238:SARO_RS07895
uniprot id: Q2G807
names: Cofactor
messages: Binds 2 iron ions per subunit.

279238:SARO RS16170
gene id: 279238:SARO_RS16170
uniprot id: Q2G3F4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

279238:SARO RS19165
gene id: 279238:SARO_RS19165
uniprot id: A4XF06
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

279238:SARO RS03520
gene id: 279238:SARO_RS03520
uniprot id: Q2GAH2
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

279238:SARO RS09790
gene id: 279238:SARO_RS09790
uniprot id: Q2G6Y1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

279238:SARO RS04230
gene id: 279238:SARO_RS04230
uniprot id: Q2GA32
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

279238:SARO RS00025
gene id: 279238:SARO_RS00025
uniprot id: Q2GCF6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

279238:SARO RS02365
gene id: 279238:SARO_RS02365
uniprot id: Q2GB53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

279238:SARO RS11875
gene id: 279238:SARO_RS11875
uniprot id: Q2G5S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

279238:SARO RS05030
gene id: 279238:SARO_RS05030
uniprot id: Q2G9M1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

279238:SARO RS14155
gene id: 279238:SARO_RS14155
uniprot id: Q2G4J7
names: Cofactor
names: Function
messages: Alkaline phosphatase with broad substrate specificity.
messages: Binds 2 Zn(2+) ions.

279238:SARO RS16855
gene id: 279238:SARO_RS16855
uniprot id: Q2G319
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

279238:SARO RS19050
gene id: 279238:SARO_RS19050
uniprot id: A4XEY3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

279238:SARO RS04510
gene id: 279238:SARO_RS04510
uniprot id: Q2G9X6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

279238:SARO RS02870
gene id: 279238:SARO_RS02870
uniprot id: Q2GAV1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

279238:SARO RS12085
gene id: 279238:SARO_RS12085
uniprot id: Q2G5N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

279238:SARO RS17030
gene id: 279238:SARO_RS17030
uniprot id: A4XDS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

279238:SARO RS08490
gene id: 279238:SARO_RS08490
uniprot id: Q2G7N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

279238:SARO RS14175
gene id: 279238:SARO_RS14175
uniprot id: Q2G4J3
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS19755
gene id: 279238:SARO_RS19755
uniprot id: A4XFC4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

279238:SARO RS13065
gene id: 279238:SARO_RS13065
uniprot id: Q2G545
names: Similarity
messages: Belongs to the CFA/CMAS family.

279238:SARO RS18825
gene id: 279238:SARO_RS18825
uniprot id: A4XET9
names: Similarity
messages: Belongs to the ParB family.

279238:SARO RS04320
gene id: 279238:SARO_RS04320
uniprot id: Q2GA15
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

279238:SARO RS00700
gene id: 279238:SARO_RS00700
uniprot id: Q2GC33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

279238:SARO RS03770
gene id: 279238:SARO_RS03770
uniprot id: Q2GAC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS04690
gene id: 279238:SARO_RS04690
uniprot id: Q2G9T9
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

279238:SARO RS04585
gene id: 279238:SARO_RS04585
uniprot id: Q2G9W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

279238:SARO RS02250
gene id: 279238:SARO_RS02250
uniprot id: Q2GB76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

279238:SARO RS11285
gene id: 279238:SARO_RS11285
uniprot id: Q2G643
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

279238:SARO RS06465
gene id: 279238:SARO_RS06465
uniprot id: Q2G8T7
names: Similarity
messages: Belongs to the DEAD box helicase family.

279238:SARO RS01100
gene id: 279238:SARO_RS01100
uniprot id: Q2GBV5
names: Similarity
messages: Belongs to the cytochrome P450 family.

279238:SARO RS07730
gene id: 279238:SARO_RS07730
uniprot id: Q2G839
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

279238:SARO RS16165
gene id: 279238:SARO_RS16165
uniprot id: Q2G3F5
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS12230
gene id: 279238:SARO_RS12230
uniprot id: Q2G5K7
names: Similarity
messages: Belongs to the UxaA family.

279238:SARO RS07285
gene id: 279238:SARO_RS07285
uniprot id: Q2G8C7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

279238:SARO RS05575
gene id: 279238:SARO_RS05575
uniprot id: Q2G9B0
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

279238:SARO RS19995
gene id: 279238:SARO_RS19995
uniprot id: A4XFH2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

279238:SARO RS13470
gene id: 279238:SARO_RS13470
uniprot id: Q2G4Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

279238:SARO RS10635
gene id: 279238:SARO_RS10635
uniprot id: Q2G6G9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

279238:SARO RS04210
gene id: 279238:SARO_RS04210
uniprot id: Q2GA36
names: Similarity
messages: Belongs to the UPF0111 family.

279238:SARO RS03045
gene id: 279238:SARO_RS03045
uniprot id: Q2GAR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

279238:SARO RS19805
gene id: 279238:SARO_RS19805
uniprot id: A4XFD4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

279238:SARO RS00505
gene id: 279238:SARO_RS00505
uniprot id: Q2GC73
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

279238:SARO RS08415
gene id: 279238:SARO_RS08415
uniprot id: Q2G7Q4
names: Similarity
messages: Belongs to the TPP enzyme family.

279238:SARO RS05310
gene id: 279238:SARO_RS05310
uniprot id: Q2G9G4
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

279238:SARO RS05505
gene id: 279238:SARO_RS05505
uniprot id: Q2G9C5
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS18955
gene id: 279238:SARO_RS18955
uniprot id: A4XEW5
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

279238:SARO RS13040
gene id: 279238:SARO_RS13040
uniprot id: Q2G550
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

279238:SARO RS07995
gene id: 279238:SARO_RS07995
uniprot id: Q2G7Y8
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

279238:SARO RS02220
gene id: 279238:SARO_RS02220
uniprot id: Q2GB82
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

279238:SARO RS12940
gene id: 279238:SARO_RS12940
uniprot id: Q2G570
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

279238:SARO RS00445
gene id: 279238:SARO_RS00445
uniprot id: Q2GC85
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

279238:SARO RS00855
gene id: 279238:SARO_RS00855
uniprot id: Q2GC02
names: Similarity
messages: Belongs to the GARS family.

279238:SARO RS06655
gene id: 279238:SARO_RS06655
uniprot id: Q2G8P9
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

279238:SARO RS04695
gene id: 279238:SARO_RS04695
uniprot id: Q2G9T8
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

279238:SARO RS10205
gene id: 279238:SARO_RS10205
uniprot id: Q2G6Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

279238:SARO RS00500
gene id: 279238:SARO_RS00500
uniprot id: Q2GC74
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

279238:SARO RS09960
gene id: 279238:SARO_RS09960
uniprot id: Q2G6V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

279238:SARO RS14440
gene id: 279238:SARO_RS14440
uniprot id: Q2G4E0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

279238:SARO RS12795
gene id: 279238:SARO_RS12795
uniprot id: Q2G596
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS03445
gene id: 279238:SARO_RS03445
uniprot id: Q2GAI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

279238:SARO RS14435
gene id: 279238:SARO_RS14435
uniprot id: Q2G4E1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

279238:SARO RS07925
gene id: 279238:SARO_RS07925
uniprot id: Q2G801
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

279238:SARO RS05950
gene id: 279238:SARO_RS05950
uniprot id: Q2G936
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

279238:SARO RS10075
gene id: 279238:SARO_RS10075
uniprot id: Q2G6T0
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

279238:SARO RS10275
gene id: 279238:SARO_RS10275
uniprot id: Q2G6P1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

279238:SARO RS04950
gene id: 279238:SARO_RS04950
uniprot id: Q2G9N7
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

279238:SARO RS06265
gene id: 279238:SARO_RS06265
uniprot id: Q2G8X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

279238:SARO RS15725
gene id: 279238:SARO_RS15725
uniprot id: Q2G3P2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

279238:SARO RS08425
gene id: 279238:SARO_RS08425
uniprot id: Q2G7Q2
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

279238:SARO RS04000
gene id: 279238:SARO_RS04000
uniprot id: Q2GA77
names: Similarity
messages: Belongs to the UPF0311 family.

279238:SARO RS08315
gene id: 279238:SARO_RS08315
uniprot id: Q2G7S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

279238:SARO RS02235
gene id: 279238:SARO_RS02235
uniprot id: Q2GB79
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

279238:SARO RS04890
gene id: 279238:SARO_RS04890
uniprot id: Q2G9P9
names: Similarity
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.

279238:SARO RS12520
gene id: 279238:SARO_RS12520
uniprot id: Q2G5F0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

279238:SARO RS01450
gene id: 279238:SARO_RS01450
uniprot id: Q2GBN6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

279238:SARO RS00670
gene id: 279238:SARO_RS00670
uniprot id: Q2GC39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

279238:SARO RS04160
gene id: 279238:SARO_RS04160
uniprot id: Q2GA46
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

279238:SARO RS14675
gene id: 279238:SARO_RS14675
uniprot id: Q2G493
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

279238:SARO RS01130
gene id: 279238:SARO_RS01130
uniprot id: Q2GBU9
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

279238:SARO RS03425
gene id: 279238:SARO_RS03425
uniprot id: Q2GAJ0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

279238:SARO RS00285
gene id: 279238:SARO_RS00285
uniprot id: Q2GCB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

279238:SARO RS12290
gene id: 279238:SARO_RS12290
uniprot id: Q2G5J5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

279238:SARO RS01145
gene id: 279238:SARO_RS01145
uniprot id: Q2GBU6
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

279238:SARO RS04170
gene id: 279238:SARO_RS04170
uniprot id: Q2GA44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

279238:SARO RS05170
gene id: 279238:SARO_RS05170
uniprot id: Q2G9J1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

279238:SARO RS01495
gene id: 279238:SARO_RS01495
uniprot id: Q2GBM7
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

279238:SARO RS04205
gene id: 279238:SARO_RS04205
uniprot id: Q2GA37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

279238:SARO RS19660
gene id: 279238:SARO_RS19660
uniprot id: A4XFA5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

279238:SARO RS13620
gene id: 279238:SARO_RS13620
uniprot id: Q2G4V4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

279238:SARO RS11555
gene id: 279238:SARO_RS11555
uniprot id: Q2G5Z1
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

279238:SARO RS09720
gene id: 279238:SARO_RS09720
uniprot id: Q2G6Z4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

279238:SARO RS09245
gene id: 279238:SARO_RS09245
uniprot id: Q2G786
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

279238:SARO RS07685
gene id: 279238:SARO_RS07685
uniprot id: Q2G849
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS05890
gene id: 279238:SARO_RS05890
uniprot id: Q2G947
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

279238:SARO RS16425
gene id: 279238:SARO_RS16425
uniprot id: Q2G3A3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

279238:SARO RS02925
gene id: 279238:SARO_RS02925
uniprot id: Q2GAT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

279238:SARO RS19870
gene id: 279238:SARO_RS19870
uniprot id: A4XFE7
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

279238:SARO RS12905
gene id: 279238:SARO_RS12905
uniprot id: Q2G577
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

279238:SARO RS05530
gene id: 279238:SARO_RS05530
uniprot id: Q2G9B9
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

279238:SARO RS01555
gene id: 279238:SARO_RS01555
uniprot id: Q2GBL5
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

279238:SARO RS01635
gene id: 279238:SARO_RS01635
uniprot id: Q2GBJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.

279238:SARO RS01565
gene id: 279238:SARO_RS01565
uniprot id: Q2GBL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbL/VirB6 family.
messages: Membrane

279238:SARO RS14555
gene id: 279238:SARO_RS14555
uniprot id: Q2G4B7
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.
messages: Binds 1 heme c group per subunit.

279238:SARO RS13125
gene id: 279238:SARO_RS13125
uniprot id: Q2G534
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

279238:SARO RS19825
gene id: 279238:SARO_RS19825
uniprot id: A4XFD8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

279238:SARO RS16535
gene id: 279238:SARO_RS16535
uniprot id: Q2G380
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

279238:SARO RS06665
gene id: 279238:SARO_RS06665
uniprot id: Q2G8P7
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

279238:SARO RS10450
gene id: 279238:SARO_RS10450
uniprot id: Q2G6K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

279238:SARO RS11295
gene id: 279238:SARO_RS11295
uniprot id: Q2G641
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

279238:SARO RS12715
gene id: 279238:SARO_RS12715
uniprot id: Q2G5B2
names: Similarity
messages: Belongs to the peptidase S9A family.

279238:SARO RS02480
gene id: 279238:SARO_RS02480
uniprot id: Q2GB30
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS11965
gene id: 279238:SARO_RS11965
uniprot id: Q2G5Q9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

279238:SARO RS06590
gene id: 279238:SARO_RS06590
uniprot id: Q2G8R2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

279238:SARO RS06280
gene id: 279238:SARO_RS06280
uniprot id: Q2G8X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

279238:SARO RS00815
gene id: 279238:SARO_RS00815
uniprot id: Q2GC09
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

279238:SARO RS09805
gene id: 279238:SARO_RS09805
uniprot id: Q2G6X8
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS05010
gene id: 279238:SARO_RS05010
uniprot id: Q2G9M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

279238:SARO RS11280
gene id: 279238:SARO_RS11280
uniprot id: Q2G644
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

279238:SARO RS12070
gene id: 279238:SARO_RS12070
uniprot id: Q2G5N8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

279238:SARO RS01430
gene id: 279238:SARO_RS01430
uniprot id: Q2GBP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

279238:SARO RS06255
gene id: 279238:SARO_RS06255
uniprot id: Q2G8X9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

279238:SARO RS17990
gene id: 279238:SARO_RS17990
uniprot id: A4XEC2
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

279238:SARO RS11185
gene id: 279238:SARO_RS11185
uniprot id: Q2G662
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

279238:SARO RS09875
gene id: 279238:SARO_RS09875
uniprot id: Q2G6W5
names: Similarity
messages: Belongs to the transketolase family.

279238:SARO RS14295
gene id: 279238:SARO_RS14295
uniprot id: Q2G4G9
names: Similarity
messages: Belongs to the PrpF family.

279238:SARO RS09055
gene id: 279238:SARO_RS09055
uniprot id: Q2G7C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

279238:SARO RS10035
gene id: 279238:SARO_RS10035
uniprot id: Q2G6T8
names: Similarity
messages: Belongs to the thioredoxin family.

279238:SARO RS10220
gene id: 279238:SARO_RS10220
uniprot id: Q2G6Q2
names: Similarity
messages: Belongs to the citrate synthase family.

279238:SARO RS12080
gene id: 279238:SARO_RS12080
uniprot id: Q2G5N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

279238:SARO RS06400
gene id: 279238:SARO_RS06400
uniprot id: Q2G8V0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

279238:SARO RS06470
gene id: 279238:SARO_RS06470
uniprot id: Q2G8T6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

279238:SARO RS07465
gene id: 279238:SARO_RS07465
uniprot id: Q2G892
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

279238:SARO RS08945
gene id: 279238:SARO_RS08945
uniprot id: Q2G7E6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

279238:SARO RS06660
gene id: 279238:SARO_RS06660
uniprot id: Q2G8P8
names: Subcellular Location Annotation
messages: Nucleus

279238:SARO RS00835
gene id: 279238:SARO_RS00835
uniprot id: Q2GC06
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

279238:SARO RS20020
gene id: 279238:SARO_RS20020
uniprot id: A4XFH7
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

279238:SARO RS14205
gene id: 279238:SARO_RS14205
uniprot id: Q2G4I7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

279238:SARO RS10830
gene id: 279238:SARO_RS10830
uniprot id: Q2G6D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

279238:SARO RS16090
gene id: 279238:SARO_RS16090
uniprot id: Q2G3H0
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

279238:SARO RS09630
gene id: 279238:SARO_RS09630
uniprot id: Q2G712
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

279238:SARO RS12500
gene id: 279238:SARO_RS12500
uniprot id: Q2G5F4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

279238:SARO RS00725
gene id: 279238:SARO_RS00725
uniprot id: Q2GC28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.

279238:SARO RS17295
gene id: 279238:SARO_RS17295
uniprot id: A4XDY0
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

279238:SARO RS02885
gene id: 279238:SARO_RS02885
uniprot id: Q2GAU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

279238:SARO RS18280
gene id: 279238:SARO_RS18280
uniprot id: A4XEI0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

279238:SARO RS00590
gene id: 279238:SARO_RS00590
uniprot id: Q2GC56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

279238:SARO RS00390
gene id: 279238:SARO_RS00390
uniprot id: Q2GC97
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

279238:SARO RS14430
gene id: 279238:SARO_RS14430
uniprot id: Q2G4E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Membrane

279238:SARO RS14135
gene id: 279238:SARO_RS14135
uniprot id: Q2G4K1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

279238:SARO RS17885
gene id: 279238:SARO_RS17885
uniprot id: A4XEA1
names: Subcellular Location Annotation
messages: Membrane

279238:SARO RS06325
gene id: 279238:SARO_RS06325
uniprot id: Q2G8W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

279238:SARO RS11220
gene id: 279238:SARO_RS11220
uniprot id: Q2G655
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

279238:SARO RS12755
gene id: 279238:SARO_RS12755
uniprot id: Q2G5A4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

279238:SARO RS07740
gene id: 279238:SARO_RS07740
uniprot id: Q2G838
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

279238:SARO RS18540
gene id: 279238:SARO_RS18540
uniprot id: A4XEN2
names: Similarity
messages: Belongs to the cytochrome P450 family.

279238:SARO RS14925
gene id: 279238:SARO_RS14925
uniprot id: Q2G444
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

279238:SARO RS06550
gene id: 279238:SARO_RS06550
uniprot id: Q2G8S0
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

279238:SARO RS08840
gene id: 279238:SARO_RS08840
uniprot id: Q2G7G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

279238:SARO RS11605
gene id: 279238:SARO_RS11605
uniprot id: Q2G5Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

279238:SARO RS07940
gene id: 279238:SARO_RS07940
uniprot id: Q2G7Z9
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

279238:SARO RS16435
gene id: 279238:SARO_RS16435
uniprot id: Q2G3A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

279238:SARO RS11340
gene id: 279238:SARO_RS11340
uniprot id: Q2G632
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

279238:SARO RS19250
gene id: 279238:SARO_RS19250
uniprot id: A4XF23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the dehydration of D-mannonate. Has no detectable activity with a panel of 70 other acid sugars (in vitro).
messages: Homotetramer.

279238:SARO RS00045
gene id: 279238:SARO_RS00045
uniprot id: Q2GCF2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

279238:SARO RS06865
gene id: 279238:SARO_RS06865
uniprot id: Q2G8L0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

279238:SARO RS06795
gene id: 279238:SARO_RS06795
uniprot id: Q2G8M3
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

279238:SARO RS14185
gene id: 279238:SARO_RS14185
uniprot id: Q2G4J1
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.