2768071:H9X71 RS10285
gene id: 2768071:H9X71_RS10285
uniprot id: A0A7L7YZY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2768071:H9X71 RS08680
gene id: 2768071:H9X71_RS08680
uniprot id: A0A7L7YZ55
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

2768071:H9X71 RS13025
gene id: 2768071:H9X71_RS13025
uniprot id: A0A7L7Z1C6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2768071:H9X71 RS12890
gene id: 2768071:H9X71_RS12890
uniprot id: A0A7L7Z1A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2768071:H9X71 RS12995
gene id: 2768071:H9X71_RS12995
uniprot id: A0A7L7Z1E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2768071:H9X71 RS11010
gene id: 2768071:H9X71_RS11010
uniprot id: A0A7L7Z0C0
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2768071:H9X71 RS14590
gene id: 2768071:H9X71_RS14590
uniprot id: A0A7L7Z1Z2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2768071:H9X71 RS00160
gene id: 2768071:H9X71_RS00160
uniprot id: A0A7L7Z2B1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2768071:H9X71 RS14725
gene id: 2768071:H9X71_RS14725
uniprot id: A0A7L7Z274
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

2768071:H9X71 RS04130
gene id: 2768071:H9X71_RS04130
uniprot id: A0A7L7Z453
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

2768071:H9X71 RS12000
gene id: 2768071:H9X71_RS12000
uniprot id: A0A7L7Z0T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2768071:H9X71 RS12980
gene id: 2768071:H9X71_RS12980
uniprot id: A0A7L7Z176
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2768071:H9X71 RS10090
gene id: 2768071:H9X71_RS10090
uniprot id: A0A7L7YZT6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2768071:H9X71 RS12765
gene id: 2768071:H9X71_RS12765
uniprot id: A0A7L7Z186
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

2768071:H9X71 RS06495
gene id: 2768071:H9X71_RS06495
uniprot id: A0A7L7Z5L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

2768071:H9X71 RS13075
gene id: 2768071:H9X71_RS13075
uniprot id: A0A7L7Z1D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2768071:H9X71 RS12885
gene id: 2768071:H9X71_RS12885
uniprot id: A0A7L7Z168
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2768071:H9X71 RS08745
gene id: 2768071:H9X71_RS08745
uniprot id: A0A7L7YZ48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

2768071:H9X71 RS14575
gene id: 2768071:H9X71_RS14575
uniprot id: A0A7L7Z275
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2768071:H9X71 RS13005
gene id: 2768071:H9X71_RS13005
uniprot id: A0A7L7Z192
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2768071:H9X71 RS12990
gene id: 2768071:H9X71_RS12990
uniprot id: A0A7L7Z1A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2768071:H9X71 RS14710
gene id: 2768071:H9X71_RS14710
uniprot id: A0A7L7Z2A6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

2768071:H9X71 RS07835
gene id: 2768071:H9X71_RS07835
uniprot id: A0A7L7YYP3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2768071:H9X71 RS03250
gene id: 2768071:H9X71_RS03250
uniprot id: A0A7L7Z3R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

2768071:H9X71 RS14585
gene id: 2768071:H9X71_RS14585
uniprot id: A0A7L7Z252
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2768071:H9X71 RS06445
gene id: 2768071:H9X71_RS06445
uniprot id: A0A7L7Z5K5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2768071:H9X71 RS07800
gene id: 2768071:H9X71_RS07800
uniprot id: A0A7L7YYR7
names: Subcellular Location Annotation
messages: Cytoplasm

2768071:H9X71 RS06520
gene id: 2768071:H9X71_RS06520
uniprot id: A0A7L7Z5H8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2768071:H9X71 RS12950
gene id: 2768071:H9X71_RS12950
uniprot id: A0A7L7Z164
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2768071:H9X71 RS14750
gene id: 2768071:H9X71_RS14750
uniprot id: A0A7L7Z288
names: Similarity
messages: Belongs to the thioredoxin family.

2768071:H9X71 RS14580
gene id: 2768071:H9X71_RS14580
uniprot id: A0A7L7Z228
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2768071:H9X71 RS05455
gene id: 2768071:H9X71_RS05455
uniprot id: A0A7L7Z591
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2768071:H9X71 RS14800
gene id: 2768071:H9X71_RS14800
uniprot id: A0A7L7Z270
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2768071:H9X71 RS13070
gene id: 2768071:H9X71_RS13070
uniprot id: A0A7L7Z1G9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2768071:H9X71 RS00005
gene id: 2768071:H9X71_RS00005
uniprot id: A0A7L7Z299
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

2768071:H9X71 RS07505
gene id: 2768071:H9X71_RS07505
uniprot id: A0A7L7YYI8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

2768071:H9X71 RS14715
gene id: 2768071:H9X71_RS14715
uniprot id: A0A7L7Z232
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

2768071:H9X71 RS13220
gene id: 2768071:H9X71_RS13220
uniprot id: A0A7L7Z1J9
names: Subcellular Location Annotation
messages: Membrane

2768071:H9X71 RS09065
gene id: 2768071:H9X71_RS09065
uniprot id: A0A7L7YZB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

2768071:H9X71 RS01745
gene id: 2768071:H9X71_RS01745
uniprot id: A0A7L7Z310
names: Similarity
messages: Belongs to the OsmC/Ohr family.

2768071:H9X71 RS12410
gene id: 2768071:H9X71_RS12410
uniprot id: A0A7L7Z0V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

2768071:H9X71 RS07155
gene id: 2768071:H9X71_RS07155
uniprot id: A0A7L7Z5P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

2768071:H9X71 RS10095
gene id: 2768071:H9X71_RS10095
uniprot id: A0A7L7YZT5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2768071:H9X71 RS12320
gene id: 2768071:H9X71_RS12320
uniprot id: A0A7L7Z106
names: Similarity
messages: Belongs to the WXG100 family.

2768071:H9X71 RS07120
gene id: 2768071:H9X71_RS07120
uniprot id: A0A7L7Z5K9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2768071:H9X71 RS05270
gene id: 2768071:H9X71_RS05270
uniprot id: A0A7L7Z4N5
names: Similarity
messages: Belongs to the HPS/KGPDC family. HPS subfamily.

2768071:H9X71 RS04925
gene id: 2768071:H9X71_RS04925
uniprot id: A0A7L7Z4S0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2768071:H9X71 RS13050
gene id: 2768071:H9X71_RS13050
uniprot id: A0A7L7Z1F1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2768071:H9X71 RS09010
gene id: 2768071:H9X71_RS09010
uniprot id: A0A7L7YZA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

2768071:H9X71 RS08740
gene id: 2768071:H9X71_RS08740
uniprot id: A0A7L7YZ39
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2768071:H9X71 RS12880
gene id: 2768071:H9X71_RS12880
uniprot id: A0A7L7Z1D1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2768071:H9X71 RS04770
gene id: 2768071:H9X71_RS04770
uniprot id: A0A7L7Z4H0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2768071:H9X71 RS02660
gene id: 2768071:H9X71_RS02660
uniprot id: A0A7L7Z3G8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2768071:H9X71 RS12970
gene id: 2768071:H9X71_RS12970
uniprot id: A0A7L7Z6I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

2768071:H9X71 RS13015
gene id: 2768071:H9X71_RS13015
uniprot id: A0A7L7Z173
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2768071:H9X71 RS13805
gene id: 2768071:H9X71_RS13805
uniprot id: A0A7L7Z1R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

2768071:H9X71 RS13380
gene id: 2768071:H9X71_RS13380
uniprot id: A0A7L7Z1D7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2768071:H9X71 RS12855
gene id: 2768071:H9X71_RS12855
uniprot id: A0A7L7Z172
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2768071:H9X71 RS12100
gene id: 2768071:H9X71_RS12100
uniprot id: A0A7L7Z0V3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

2768071:H9X71 RS08905
gene id: 2768071:H9X71_RS08905
uniprot id: A0A7L7YZ83
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2768071:H9X71 RS08900
gene id: 2768071:H9X71_RS08900
uniprot id: A0A7L7YZ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

2768071:H9X71 RS12800
gene id: 2768071:H9X71_RS12800
uniprot id: A0A7L7Z187
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2768071:H9X71 RS08940
gene id: 2768071:H9X71_RS08940
uniprot id: A0A7L7YZ93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2768071:H9X71 RS03920
gene id: 2768071:H9X71_RS03920
uniprot id: A0A7L7Z4C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2768071:H9X71 RS00070
gene id: 2768071:H9X71_RS00070
uniprot id: A0A7L7Z281
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

2768071:H9X71 RS06995
gene id: 2768071:H9X71_RS06995
uniprot id: A0A7L7Z5J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2768071:H9X71 RS12190
gene id: 2768071:H9X71_RS12190
uniprot id: A0A7L7Z0X9
names: Similarity
messages: Belongs to the UDPGP type 2 family.

2768071:H9X71 RS13795
gene id: 2768071:H9X71_RS13795
uniprot id: A0A7L7Z1M1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2768071:H9X71 RS12895
gene id: 2768071:H9X71_RS12895
uniprot id: A0A7L7Z152
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2768071:H9X71 RS02380
gene id: 2768071:H9X71_RS02380
uniprot id: A0A7L7Z3B6
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

2768071:H9X71 RS06210
gene id: 2768071:H9X71_RS06210
uniprot id: A0A7L7Z547
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2768071:H9X71 RS12900
gene id: 2768071:H9X71_RS12900
uniprot id: A0A7L7Z1A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.