2754694:H0S70 RS10990
gene id: 2754694:H0S70_RS10990
uniprot id: A0A7H1DV68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

2754694:H0S70 RS08930
gene id: 2754694:H0S70_RS08930
uniprot id: A0A7H1DU52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2754694:H0S70 RS08915
gene id: 2754694:H0S70_RS08915
uniprot id: A0A7H1DU49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2754694:H0S70 RS08470
gene id: 2754694:H0S70_RS08470
uniprot id: A0A7H1DTW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

2754694:H0S70 RS08670
gene id: 2754694:H0S70_RS08670
uniprot id: A0A7H1DU02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2754694:H0S70 RS12990
gene id: 2754694:H0S70_RS12990
uniprot id: A0A7H1DW67
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

2754694:H0S70 RS10985
gene id: 2754694:H0S70_RS10985
uniprot id: A0A7H1DV67
names: Similarity
messages: Belongs to the MreC family.

2754694:H0S70 RS08875
gene id: 2754694:H0S70_RS08875
uniprot id: A0A7H1DU41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2754694:H0S70 RS05940
gene id: 2754694:H0S70_RS05940
uniprot id: A0A7H1DZU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2754694:H0S70 RS00185
gene id: 2754694:H0S70_RS00185
uniprot id: A0A7H1DWU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2754694:H0S70 RS04455
gene id: 2754694:H0S70_RS04455
uniprot id: A0A7H1DZ23
names: Similarity
messages: Belongs to the OsmC/Ohr family.

2754694:H0S70 RS06165
gene id: 2754694:H0S70_RS06165
uniprot id: A0A7H1DZY7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

2754694:H0S70 RS08675
gene id: 2754694:H0S70_RS08675
uniprot id: A0A7H1DU03
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2754694:H0S70 RS11815
gene id: 2754694:H0S70_RS11815
uniprot id: A0A7H1DVL6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

2754694:H0S70 RS12710
gene id: 2754694:H0S70_RS12710
uniprot id: A0A7H1DW19
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

2754694:H0S70 RS10840
gene id: 2754694:H0S70_RS10840
uniprot id: A0A7H1DV39
names: Similarity
messages: Belongs to the UPF0102 family.

2754694:H0S70 RS03375
gene id: 2754694:H0S70_RS03375
uniprot id: A0A7H1DYH5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

2754694:H0S70 RS04400
gene id: 2754694:H0S70_RS04400
uniprot id: A0A7H1DZ13
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

2754694:H0S70 RS07565
gene id: 2754694:H0S70_RS07565
uniprot id: A0A7H1DTF5
names: Similarity
messages: Belongs to the barstar family.

2754694:H0S70 RS08950
gene id: 2754694:H0S70_RS08950
uniprot id: A0A7H1DU55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2754694:H0S70 RS11760
gene id: 2754694:H0S70_RS11760
uniprot id: A0A7H1DVK5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

2754694:H0S70 RS12830
gene id: 2754694:H0S70_RS12830
uniprot id: A0A7H1DW41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

2754694:H0S70 RS08860
gene id: 2754694:H0S70_RS08860
uniprot id: A0A7H1DU38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2754694:H0S70 RS05270
gene id: 2754694:H0S70_RS05270
uniprot id: A0A7H1DZH7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

2754694:H0S70 RS05260
gene id: 2754694:H0S70_RS05260
uniprot id: A0A7H1DZH5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

2754694:H0S70 RS08195
gene id: 2754694:H0S70_RS08195
uniprot id: A0A7H1DTR3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2754694:H0S70 RS04195
gene id: 2754694:H0S70_RS04195
uniprot id: A0A7H1DYX6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2754694:H0S70 RS08940
gene id: 2754694:H0S70_RS08940
uniprot id: A0A7H1DU53
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2754694:H0S70 RS06880
gene id: 2754694:H0S70_RS06880
uniprot id: A0A7H1DT24
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

2754694:H0S70 RS08850
gene id: 2754694:H0S70_RS08850
uniprot id: A0A7H1DU36
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2754694:H0S70 RS05265
gene id: 2754694:H0S70_RS05265
uniprot id: A0A7H1DZH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

2754694:H0S70 RS12465
gene id: 2754694:H0S70_RS12465
uniprot id: A0A7H1DVX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

2754694:H0S70 RS05960
gene id: 2754694:H0S70_RS05960
uniprot id: A0A7H1DZU8
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

2754694:H0S70 RS08680
gene id: 2754694:H0S70_RS08680
uniprot id: A0A7H1DU04
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

2754694:H0S70 RS02370
gene id: 2754694:H0S70_RS02370
uniprot id: A0A7H1DXZ6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2754694:H0S70 RS08370
gene id: 2754694:H0S70_RS08370
uniprot id: A0A7H1DTU7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2754694:H0S70 RS08865
gene id: 2754694:H0S70_RS08865
uniprot id: A0A7H1DU39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2754694:H0S70 RS12345
gene id: 2754694:H0S70_RS12345
uniprot id: A0A7H1DVV4
names: Subcellular Location Annotation
messages: Nucleus

2754694:H0S70 RS09345
gene id: 2754694:H0S70_RS09345
uniprot id: A0A7H1DUB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

2754694:H0S70 RS11535
gene id: 2754694:H0S70_RS11535
uniprot id: A0A7H1DVG7
names: Similarity
messages: Belongs to the thioredoxin family.

2754694:H0S70 RS10440
gene id: 2754694:H0S70_RS10440
uniprot id: A0A7H1DUW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

2754694:H0S70 RS10785
gene id: 2754694:H0S70_RS10785
uniprot id: A0A7H1DV28
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2754694:H0S70 RS11070
gene id: 2754694:H0S70_RS11070
uniprot id: A0A7H1DV83
names: Similarity
messages: Belongs to the DprA/Smf family.

2754694:H0S70 RS08635
gene id: 2754694:H0S70_RS08635
uniprot id: A0A7H1DTZ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

2754694:H0S70 RS02375
gene id: 2754694:H0S70_RS02375
uniprot id: A0A7H1DXZ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2754694:H0S70 RS09020
gene id: 2754694:H0S70_RS09020
uniprot id: A0A7H1DU69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2754694:H0S70 RS01145
gene id: 2754694:H0S70_RS01145
uniprot id: A0A7H1DXC3
names: Similarity
messages: Belongs to the thioredoxin family.

2754694:H0S70 RS04060
gene id: 2754694:H0S70_RS04060
uniprot id: A0A7H1DYV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

2754694:H0S70 RS08945
gene id: 2754694:H0S70_RS08945
uniprot id: A0A7H1DU54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2754694:H0S70 RS11955
gene id: 2754694:H0S70_RS11955
uniprot id: A0A7H1DVP3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

2754694:H0S70 RS09230
gene id: 2754694:H0S70_RS09230
uniprot id: A0A7H1DUA8
names: Similarity
messages: Belongs to the RutC family.

2754694:H0S70 RS00440
gene id: 2754694:H0S70_RS00440
uniprot id: A0A7H1DWY8
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2754694:H0S70 RS04575
gene id: 2754694:H0S70_RS04575
uniprot id: A0A7H1DZ47
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2754694:H0S70 RS00820
gene id: 2754694:H0S70_RS00820
uniprot id: A0A7H1DX59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

2754694:H0S70 RS08280
gene id: 2754694:H0S70_RS08280
uniprot id: A0A7H1DTS9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2754694:H0S70 RS09025
gene id: 2754694:H0S70_RS09025
uniprot id: A0A7H1DU70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2754694:H0S70 RS13535
gene id: 2754694:H0S70_RS13535
uniprot id: A0A7H1DWG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

2754694:H0S70 RS08925
gene id: 2754694:H0S70_RS08925
uniprot id: A0A7H1DU51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2754694:H0S70 RS04535
gene id: 2754694:H0S70_RS04535
uniprot id: A0A7H1DZ39
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2754694:H0S70 RS10585
gene id: 2754694:H0S70_RS10585
uniprot id: A0A7H1DUZ2
names: Similarity
messages: Belongs to the SufE family.

2754694:H0S70 RS12055
gene id: 2754694:H0S70_RS12055
uniprot id: A0A7H1DVQ9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

2754694:H0S70 RS08375
gene id: 2754694:H0S70_RS08375
uniprot id: A0A7H1DTU8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2754694:H0S70 RS05365
gene id: 2754694:H0S70_RS05365
uniprot id: A0A7H1DZJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

2754694:H0S70 RS04850
gene id: 2754694:H0S70_RS04850
uniprot id: A0A7H1DZA0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

2754694:H0S70 RS10330
gene id: 2754694:H0S70_RS10330
uniprot id: A0A7H1DUU7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

2754694:H0S70 RS12865
gene id: 2754694:H0S70_RS12865
uniprot id: A0A7H1DW48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

2754694:H0S70 RS09085
gene id: 2754694:H0S70_RS09085
uniprot id: A0A7H1DU82
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

2754694:H0S70 RS09210
gene id: 2754694:H0S70_RS09210
uniprot id: A0A7H1DUA5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

2754694:H0S70 RS10180
gene id: 2754694:H0S70_RS10180
uniprot id: A0A7H1DUR8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2754694:H0S70 RS11295
gene id: 2754694:H0S70_RS11295
uniprot id: A0A7H1DVC4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

2754694:H0S70 RS10800
gene id: 2754694:H0S70_RS10800
uniprot id: A0A7H1DV31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

2754694:H0S70 RS04770
gene id: 2754694:H0S70_RS04770
uniprot id: A0A7H1DZ85
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

2754694:H0S70 RS08890
gene id: 2754694:H0S70_RS08890
uniprot id: A0A7H1DU44
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2754694:H0S70 RS00325
gene id: 2754694:H0S70_RS00325
uniprot id: A0A7H1DWW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

2754694:H0S70 RS12995
gene id: 2754694:H0S70_RS12995
uniprot id: A0A7H1DW68
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2754694:H0S70 RS10965
gene id: 2754694:H0S70_RS10965
uniprot id: A0A7H1DV63
names: Similarity
messages: Belongs to the peptidase C40 family.

2754694:H0S70 RS08980
gene id: 2754694:H0S70_RS08980
uniprot id: A0A7H1DU61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2754694:H0S70 RS08870
gene id: 2754694:H0S70_RS08870
uniprot id: A0A7H1DU40
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2754694:H0S70 RS13605
gene id: 2754694:H0S70_RS13605
uniprot id: A0A7H1DWH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

2754694:H0S70 RS00925
gene id: 2754694:H0S70_RS00925
uniprot id: A0A7H1DX80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

2754694:H0S70 RS08960
gene id: 2754694:H0S70_RS08960
uniprot id: A0A7H1DU57
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2754694:H0S70 RS02645
gene id: 2754694:H0S70_RS02645
uniprot id: A0A7H1DY48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

2754694:H0S70 RS10120
gene id: 2754694:H0S70_RS10120
uniprot id: A0A7H1DUQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

2754694:H0S70 RS08885
gene id: 2754694:H0S70_RS08885
uniprot id: A0A7H1DU43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2754694:H0S70 RS13010
gene id: 2754694:H0S70_RS13010
uniprot id: A0A7H1DW71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2754694:H0S70 RS02300
gene id: 2754694:H0S70_RS02300
uniprot id: A0A7H1DXY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2754694:H0S70 RS08910
gene id: 2754694:H0S70_RS08910
uniprot id: A0A7H1DU48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2754694:H0S70 RS13960
gene id: 2754694:H0S70_RS13960
uniprot id: A0A7H1DWP3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2754694:H0S70 RS03210
gene id: 2754694:H0S70_RS03210
uniprot id: A0A7H1DYE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

2754694:H0S70 RS12715
gene id: 2754694:H0S70_RS12715
uniprot id: A0A7H1DW20
names: Similarity
messages: Belongs to the YoeB family.

2754694:H0S70 RS12680
gene id: 2754694:H0S70_RS12680
uniprot id: A0A7H1DW14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

2754694:H0S70 RS13565
gene id: 2754694:H0S70_RS13565
uniprot id: A0A7H1DWH1
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

2754694:H0S70 RS06540
gene id: 2754694:H0S70_RS06540
uniprot id: A0A7H1E042
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2754694:H0S70 RS06735
gene id: 2754694:H0S70_RS06735
uniprot id: A0A7H1E076
names: Similarity
messages: Belongs to the universal stress protein A family.

2754694:H0S70 RS04605
gene id: 2754694:H0S70_RS04605
uniprot id: A0A7H1DZ53
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2754694:H0S70 RS09010
gene id: 2754694:H0S70_RS09010
uniprot id: A0A7H1DU67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2754694:H0S70 RS03695
gene id: 2754694:H0S70_RS03695
uniprot id: A0A7H1DYN5
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

2754694:H0S70 RS12720
gene id: 2754694:H0S70_RS12720
uniprot id: A0A7H1DW21
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

2754694:H0S70 RS08955
gene id: 2754694:H0S70_RS08955
uniprot id: A0A7H1DU56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2754694:H0S70 RS03075
gene id: 2754694:H0S70_RS03075
uniprot id: A0A7H1DYC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

2754694:H0S70 RS06170
gene id: 2754694:H0S70_RS06170
uniprot id: A0A7H1DZY8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2754694:H0S70 RS04940
gene id: 2754694:H0S70_RS04940
uniprot id: A0A7H1DZB7
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.