2749961:BHS00 RS03950
gene id: 2749961:BHS00_RS03950
uniprot id: A0A7L4WAR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

2749961:BHS00 RS06780
gene id: 2749961:BHS00_RS06780
uniprot id: A0A7L4W7T2
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

2749961:BHS00 RS04820
gene id: 2749961:BHS00_RS04820
uniprot id: A0A7L4W8X7
names: Similarity
messages: Belongs to the pyruvate kinase family.

2749961:BHS00 RS05155
gene id: 2749961:BHS00_RS05155
uniprot id: A0A7L4W934
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

2749961:BHS00 RS02115
gene id: 2749961:BHS00_RS02115
uniprot id: A0A7L4W5U4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2749961:BHS00 RS09350
gene id: 2749961:BHS00_RS09350
uniprot id: A0A7L4W8R5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2749961:BHS00 RS04275
gene id: 2749961:BHS00_RS04275
uniprot id: A0A7L4W8R3
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

2749961:BHS00 RS09915
gene id: 2749961:BHS00_RS09915
uniprot id: A0A7L4WCJ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2749961:BHS00 RS07485
gene id: 2749961:BHS00_RS07485
uniprot id: A0A7L4W7S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.
messages: Membrane

2749961:BHS00 RS02190
gene id: 2749961:BHS00_RS02190
uniprot id: A0A7L4W6J2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2749961:BHS00 RS01315
gene id: 2749961:BHS00_RS01315
uniprot id: A0A7L4W7K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HPr family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
messages: P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity.

2749961:BHS00 RS06275
gene id: 2749961:BHS00_RS06275
uniprot id: A0A7L4WAP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

2749961:BHS00 RS05410
gene id: 2749961:BHS00_RS05410
uniprot id: A0A7L4W761
names: Similarity
messages: Belongs to the TPP enzyme family.

2749961:BHS00 RS05195
gene id: 2749961:BHS00_RS05195
uniprot id: A0A7L4W721
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Cell membrane
messages: Membrane

2749961:BHS00 RS09375
gene id: 2749961:BHS00_RS09375
uniprot id: A0A7L4WB38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

2749961:BHS00 RS05145
gene id: 2749961:BHS00_RS05145
uniprot id: A0A7L4W712
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2749961:BHS00 RS06695
gene id: 2749961:BHS00_RS06695
uniprot id: A0A7L4W9U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

2749961:BHS00 RS00775
gene id: 2749961:BHS00_RS00775
uniprot id: A0A7L4W4Z9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2749961:BHS00 RS00450
gene id: 2749961:BHS00_RS00450
uniprot id: A0A7L4W579
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

2749961:BHS00 RS06710
gene id: 2749961:BHS00_RS06710
uniprot id: A0A7L4W8N5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2749961:BHS00 RS07720
gene id: 2749961:BHS00_RS07720
uniprot id: A0A7L4W8C4
names: Subcellular Location Annotation
messages: Membrane

2749961:BHS00 RS00035
gene id: 2749961:BHS00_RS00035
uniprot id: A0A7L4WAK6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

2749961:BHS00 RS09310
gene id: 2749961:BHS00_RS09310
uniprot id: A0A7L4W936
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2749961:BHS00 RS07360
gene id: 2749961:BHS00_RS07360
uniprot id: A0A7L4WA54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

2749961:BHS00 RS09390
gene id: 2749961:BHS00_RS09390
uniprot id: A0A7L4W9Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2749961:BHS00 RS09370
gene id: 2749961:BHS00_RS09370
uniprot id: A0A7L4WB98
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2749961:BHS00 RS05640
gene id: 2749961:BHS00_RS05640
uniprot id: A0A7L4WA02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

2749961:BHS00 RS09300
gene id: 2749961:BHS00_RS09300
uniprot id: A0A7L4W931
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2749961:BHS00 RS08880
gene id: 2749961:BHS00_RS08880
uniprot id: A0A7L4W8W9
names: Similarity
messages: Belongs to the UPF0473 family.

2749961:BHS00 RS07430
gene id: 2749961:BHS00_RS07430
uniprot id: A0A7L4WAW0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

2749961:BHS00 RS02920
gene id: 2749961:BHS00_RS02920
uniprot id: A0A7L4W7Y4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

2749961:BHS00 RS09365
gene id: 2749961:BHS00_RS09365
uniprot id: A0A7L4W945
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2749961:BHS00 RS07545
gene id: 2749961:BHS00_RS07545
uniprot id: A0A7L4W7T7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

2749961:BHS00 RS01110
gene id: 2749961:BHS00_RS01110
uniprot id: A0A7L4W532
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

2749961:BHS00 RS05290
gene id: 2749961:BHS00_RS05290
uniprot id: A0A7L4W706
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

2749961:BHS00 RS04140
gene id: 2749961:BHS00_RS04140
uniprot id: A0A7L4W656
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
messages: Cell membrane
messages: Membrane

2749961:BHS00 RS06705
gene id: 2749961:BHS00_RS06705
uniprot id: A0A7L4W9X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

2749961:BHS00 RS03010
gene id: 2749961:BHS00_RS03010
uniprot id: A0A7L4W662
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

2749961:BHS00 RS03450
gene id: 2749961:BHS00_RS03450
uniprot id: A0A7L4W5W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

2749961:BHS00 RS01955
gene id: 2749961:BHS00_RS01955
uniprot id: A0A7L4W5D8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2749961:BHS00 RS09440
gene id: 2749961:BHS00_RS09440
uniprot id: A0A7L4WA06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2749961:BHS00 RS07855
gene id: 2749961:BHS00_RS07855
uniprot id: A0A7L4W7U4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

2749961:BHS00 RS02310
gene id: 2749961:BHS00_RS02310
uniprot id: A0A7L4W7S9
names: Similarity
messages: Belongs to the YggT family.

2749961:BHS00 RS05095
gene id: 2749961:BHS00_RS05095
uniprot id: A0A7L4W701
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

2749961:BHS00 RS09410
gene id: 2749961:BHS00_RS09410
uniprot id: A0A7L4W8M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2749961:BHS00 RS07715
gene id: 2749961:BHS00_RS07715
uniprot id: A0A7L4W7S3
names: Subcellular Location Annotation
messages: Membrane

2749961:BHS00 RS08500
gene id: 2749961:BHS00_RS08500
uniprot id: A0A7L4W8B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

2749961:BHS00 RS09270
gene id: 2749961:BHS00_RS09270
uniprot id: A0A7L4WB16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

2749961:BHS00 RS07480
gene id: 2749961:BHS00_RS07480
uniprot id: A0A7L4WAX0
names: Similarity
messages: Belongs to the DtxR/MntR family.

2749961:BHS00 RS02335
gene id: 2749961:BHS00_RS02335
uniprot id: A0A7L4W5I6
names: Subcellular Location Annotation
messages: Membrane

2749961:BHS00 RS09345
gene id: 2749961:BHS00_RS09345
uniprot id: A0A7L4WBT4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2749961:BHS00 RS09395
gene id: 2749961:BHS00_RS09395
uniprot id: A0A7L4WBU6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2749961:BHS00 RS06835
gene id: 2749961:BHS00_RS06835
uniprot id: A0A7L4W7C4
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

2749961:BHS00 RS05455
gene id: 2749961:BHS00_RS05455
uniprot id: A0A7L4W6N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

2749961:BHS00 RS04260
gene id: 2749961:BHS00_RS04260
uniprot id: A0A7L4W8P8
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

2749961:BHS00 RS01505
gene id: 2749961:BHS00_RS01505
uniprot id: A0A7L4W9P9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2749961:BHS00 RS04750
gene id: 2749961:BHS00_RS04750
uniprot id: A0A7L4W6U5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.
messages: Belongs to the DltC family.
messages: Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

2749961:BHS00 RS08385
gene id: 2749961:BHS00_RS08385
uniprot id: A0A7L4W9G8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2749961:BHS00 RS00960
gene id: 2749961:BHS00_RS00960
uniprot id: A0A7L4W5E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.

2749961:BHS00 RS07490
gene id: 2749961:BHS00_RS07490
uniprot id: A0A7L4W870
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2749961:BHS00 RS00630
gene id: 2749961:BHS00_RS00630
uniprot id: A0A7L4W5A8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

2749961:BHS00 RS01100
gene id: 2749961:BHS00_RS01100
uniprot id: A0A7L4W644
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

2749961:BHS00 RS07225
gene id: 2749961:BHS00_RS07225
uniprot id: A0A7L4W9Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2749961:BHS00 RS02490
gene id: 2749961:BHS00_RS02490
uniprot id: A0A7L4W6M7
names: Cofactor
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

2749961:BHS00 RS09265
gene id: 2749961:BHS00_RS09265
uniprot id: A0A7L4WB75
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2749961:BHS00 RS07670
gene id: 2749961:BHS00_RS07670
uniprot id: A0A7L4W8B7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

2749961:BHS00 RS07615
gene id: 2749961:BHS00_RS07615
uniprot id: A0A7L4WBY3
names: Subcellular Location Annotation
messages: Membrane

2749961:BHS00 RS09800
gene id: 2749961:BHS00_RS09800
uniprot id: A0A7L4WC82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

2749961:BHS00 RS06845
gene id: 2749961:BHS00_RS06845
uniprot id: A0A7L4WC34
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

2749961:BHS00 RS01130
gene id: 2749961:BHS00_RS01130
uniprot id: A0A7L4WAL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.

2749961:BHS00 RS02770
gene id: 2749961:BHS00_RS02770
uniprot id: A0A7L4W808
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

2749961:BHS00 RS09455
gene id: 2749961:BHS00_RS09455
uniprot id: A0A7L4W962
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

2749961:BHS00 RS01095
gene id: 2749961:BHS00_RS01095
uniprot id: A0A7L4W778
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2749961:BHS00 RS09415
gene id: 2749961:BHS00_RS09415
uniprot id: A0A7L4W955
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2749961:BHS00 RS07540
gene id: 2749961:BHS00_RS07540
uniprot id: A0A7L4WAY0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

2749961:BHS00 RS00795
gene id: 2749961:BHS00_RS00795
uniprot id: A0A7L4W6U9
names: Similarity
messages: Belongs to the universal stress protein A family.

2749961:BHS00 RS08390
gene id: 2749961:BHS00_RS08390
uniprot id: A0A7L4WBB7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2749961:BHS00 RS07590
gene id: 2749961:BHS00_RS07590
uniprot id: A0A7L4WAY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

2749961:BHS00 RS09720
gene id: 2749961:BHS00_RS09720
uniprot id: A0A7L4W8Y0
names: Subcellular Location Annotation
messages: Cytoplasm

2749961:BHS00 RS06315
gene id: 2749961:BHS00_RS06315
uniprot id: A0A7L4W7L6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2749961:BHS00 RS01970
gene id: 2749961:BHS00_RS01970
uniprot id: A0A7L4W7G8
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

2749961:BHS00 RS05140
gene id: 2749961:BHS00_RS05140
uniprot id: A0A7L4W6I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2749961:BHS00 RS07580
gene id: 2749961:BHS00_RS07580
uniprot id: A0A7L4WAC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2749961:BHS00 RS08790
gene id: 2749961:BHS00_RS08790
uniprot id: A0A7L4WAT7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2749961:BHS00 RS09750
gene id: 2749961:BHS00_RS09750
uniprot id: A0A7L4WCG0
names: Subcellular Location Annotation
messages: Membrane

2749961:BHS00 RS08785
gene id: 2749961:BHS00_RS08785
uniprot id: A0A7L4WAZ8
names: Similarity
messages: Belongs to the asp23 family.

2749961:BHS00 RS01930
gene id: 2749961:BHS00_RS01930
uniprot id: A0A7L4W8K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

2749961:BHS00 RS07675
gene id: 2749961:BHS00_RS07675
uniprot id: A0A7L4WAD7
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

2749961:BHS00 RS06675
gene id: 2749961:BHS00_RS06675
uniprot id: A0A7L4W7R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

2749961:BHS00 RS00510
gene id: 2749961:BHS00_RS00510
uniprot id: A0A7L4W4X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2749961:BHS00 RS03395
gene id: 2749961:BHS00_RS03395
uniprot id: A0A7L4W665
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2749961:BHS00 RS04525
gene id: 2749961:BHS00_RS04525
uniprot id: A0A7L4W6Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

2749961:BHS00 RS02945
gene id: 2749961:BHS00_RS02945
uniprot id: A0A7L4W5R1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

2749961:BHS00 RS09380
gene id: 2749961:BHS00_RS09380
uniprot id: A0A7L4WC88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2749961:BHS00 RS09430
gene id: 2749961:BHS00_RS09430
uniprot id: A0A7L4WC99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

2749961:BHS00 RS02425
gene id: 2749961:BHS00_RS02425
uniprot id: A0A7L4W7U8
names: Similarity
messages: Belongs to the CtsR family.

2749961:BHS00 RS05355
gene id: 2749961:BHS00_RS05355
uniprot id: A0A7L4W752
names: Similarity
messages: Belongs to the OsmC/Ohr family.

2749961:BHS00 RS05755
gene id: 2749961:BHS00_RS05755
uniprot id: A0A7L4W865
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

2749961:BHS00 RS07005
gene id: 2749961:BHS00_RS07005
uniprot id: A0A7L4W9Z6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2749961:BHS00 RS02135
gene id: 2749961:BHS00_RS02135
uniprot id: A0A7L4W7Q0
names: Similarity
messages: Belongs to the UPF0346 family.

2749961:BHS00 RS00255
gene id: 2749961:BHS00_RS00255
uniprot id: A0A7L4W7T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2749961:BHS00 RS02650
gene id: 2749961:BHS00_RS02650
uniprot id: A0A7L4W6P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

2749961:BHS00 RS09960
gene id: 2749961:BHS00_RS09960
uniprot id: A0A7L4W9F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family. YeeN subfamily.
messages: Cytoplasm

2749961:BHS00 RS02745
gene id: 2749961:BHS00_RS02745
uniprot id: A0A7L4W627
names: Subcellular Location Annotation
messages: Membrane

2749961:BHS00 RS08900
gene id: 2749961:BHS00_RS08900
uniprot id: A0A7L4WB19
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2749961:BHS00 RS03560
gene id: 2749961:BHS00_RS03560
uniprot id: A0A7L4W689
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

2749961:BHS00 RS09385
gene id: 2749961:BHS00_RS09385
uniprot id: A0A7L4WBA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2749961:BHS00 RS05890
gene id: 2749961:BHS00_RS05890
uniprot id: A0A7L4W6W5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2749961:BHS00 RS02195
gene id: 2749961:BHS00_RS02195
uniprot id: A0A7L4W806
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

2749961:BHS00 RS09400
gene id: 2749961:BHS00_RS09400
uniprot id: A0A7L4W8R7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2749961:BHS00 RS07560
gene id: 2749961:BHS00_RS07560
uniprot id: A0A7L4W897
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a set of proteins in which some residues (ACT_SITE, NP_BIND, REGION and BINDING) are not conserved.

2749961:BHS00 RS00260
gene id: 2749961:BHS00_RS00260
uniprot id: A0A7L4W6T8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2749961:BHS00 RS07665
gene id: 2749961:BHS00_RS07665
uniprot id: A0A7L4W7R3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

2749961:BHS00 RS07635
gene id: 2749961:BHS00_RS07635
uniprot id: A0A7L4WBD0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

2749961:BHS00 RS09425
gene id: 2749961:BHS00_RS09425
uniprot id: A0A7L4WB48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2749961:BHS00 RS02670
gene id: 2749961:BHS00_RS02670
uniprot id: A0A7L4WCX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

2749961:BHS00 RS02800
gene id: 2749961:BHS00_RS02800
uniprot id: A0A7L4W603
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2749961:BHS00 RS09325
gene id: 2749961:BHS00_RS09325
uniprot id: A0A7L4WB23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2749961:BHS00 RS01495
gene id: 2749961:BHS00_RS01495
uniprot id: A0A7L4W7N3
names: Similarity
messages: Belongs to the P(II) protein family.

2749961:BHS00 RS02925
gene id: 2749961:BHS00_RS02925
uniprot id: A0A7L4W916
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

2749961:BHS00 RS06580
gene id: 2749961:BHS00_RS06580
uniprot id: A0A7L4W9T8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2749961:BHS00 RS05885
gene id: 2749961:BHS00_RS05885
uniprot id: A0A7L4W9X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

2749961:BHS00 RS07050
gene id: 2749961:BHS00_RS07050
uniprot id: A0A7L4W805
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

2749961:BHS00 RS07600
gene id: 2749961:BHS00_RS07600
uniprot id: A0A7L4W891
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.

2749961:BHS00 RS09420
gene id: 2749961:BHS00_RS09420
uniprot id: A0A7L4WBB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2749961:BHS00 RS08860
gene id: 2749961:BHS00_RS08860
uniprot id: A0A7L4W9Q8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

2749961:BHS00 RS03175
gene id: 2749961:BHS00_RS03175
uniprot id: A0A7L4WCH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

2749961:BHS00 RS09755
gene id: 2749961:BHS00_RS09755
uniprot id: A0A7L4WBI5
names: Subcellular Location Annotation
messages: Membrane

2749961:BHS00 RS06840
gene id: 2749961:BHS00_RS06840
uniprot id: A0A7L4W7W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

2749961:BHS00 RS00505
gene id: 2749961:BHS00_RS00505
uniprot id: A0A7L4W985
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2749961:BHS00 RS04370
gene id: 2749961:BHS00_RS04370
uniprot id: A0A7L4W8P4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

2749961:BHS00 RS04320
gene id: 2749961:BHS00_RS04320
uniprot id: A0A7L4W9M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

2749961:BHS00 RS04305
gene id: 2749961:BHS00_RS04305
uniprot id: A0A7L4W6L7
names: Subcellular Location Annotation
messages: Membrane

2749961:BHS00 RS06455
gene id: 2749961:BHS00_RS06455
uniprot id: A0A7L4W7M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

2749961:BHS00 RS09315
gene id: 2749961:BHS00_RS09315
uniprot id: A0A7L4WB87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2749961:BHS00 RS01135
gene id: 2749961:BHS00_RS01135
uniprot id: A0A7L4W5G8
names: Similarity
messages: Belongs to the UPF0223 family.

2749961:BHS00 RS01530
gene id: 2749961:BHS00_RS01530
uniprot id: A0A7L4W798
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2749961:BHS00 RS07565
gene id: 2749961:BHS00_RS07565
uniprot id: A0A7L4WAB7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

2749961:BHS00 RS07780
gene id: 2749961:BHS00_RS07780
uniprot id: A0A7L4W7X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

2749961:BHS00 RS03610
gene id: 2749961:BHS00_RS03610
uniprot id: A0A7L4W697
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
messages: Cell membrane
messages: Membrane

2749961:BHS00 RS03430
gene id: 2749961:BHS00_RS03430
uniprot id: A0A7L4W700
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

2749961:BHS00 RS09405
gene id: 2749961:BHS00_RS09405
uniprot id: A0A7L4W951
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2749961:BHS00 RS02420
gene id: 2749961:BHS00_RS02420
uniprot id: A0A7L4W8S7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.