2745518:HU722 RS26775
gene id: 2745518:HU722_RS26775
uniprot id: A0A8H9YRB9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2745518:HU722 RS10910
gene id: 2745518:HU722_RS10910
uniprot id: A0A8I0CY75
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2745518:HU722 RS26065
gene id: 2745518:HU722_RS26065
uniprot id: A0A8H9YPH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

2745518:HU722 RS13480
gene id: 2745518:HU722_RS13480
uniprot id: A0A8H9YYK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS10270
gene id: 2745518:HU722_RS10270
uniprot id: A0A8H9Z2E3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745518:HU722 RS09575
gene id: 2745518:HU722_RS09575
uniprot id: A0A8H9YS64
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2745518:HU722 RS18305
gene id: 2745518:HU722_RS18305
uniprot id: A0A8H9YQT1
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

2745518:HU722 RS26595
gene id: 2745518:HU722_RS26595
uniprot id: A0A8H9YPN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2745518:HU722 RS26125
gene id: 2745518:HU722_RS26125
uniprot id: A0A8I0CW38
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS06110
gene id: 2745518:HU722_RS06110
uniprot id: A0A8H9YUI0
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

2745518:HU722 RS10055
gene id: 2745518:HU722_RS10055
uniprot id: A0A8I0CX09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

2745518:HU722 RS02665
gene id: 2745518:HU722_RS02665
uniprot id: A0A8I0CV61
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

2745518:HU722 RS24440
gene id: 2745518:HU722_RS24440
uniprot id: A0A8H9Z057
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane
messages: The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains.

2745518:HU722 RS05875
gene id: 2745518:HU722_RS05875
uniprot id: A0A8H9YUL3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

2745518:HU722 RS00670
gene id: 2745518:HU722_RS00670
uniprot id: A0A8H9YUV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS10730
gene id: 2745518:HU722_RS10730
uniprot id: A0A8H9YUA8
names: Similarity
messages: Belongs to the diaminopimelate epimerase family.

2745518:HU722 RS05445
gene id: 2745518:HU722_RS05445
uniprot id: A0A8I0CXP5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

2745518:HU722 RS20730
gene id: 2745518:HU722_RS20730
uniprot id: A0A8H9YHZ1
names: Similarity
messages: Belongs to the MotB family.

2745518:HU722 RS25005
gene id: 2745518:HU722_RS25005
uniprot id: A0A8H9YPG9
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS27075
gene id: 2745518:HU722_RS27075
uniprot id: A0A8H9YRH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS22600
gene id: 2745518:HU722_RS22600
uniprot id: A0A8H9YJJ5
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

2745518:HU722 RS19925
gene id: 2745518:HU722_RS19925
uniprot id: A0A8I0D0F5
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS10810
gene id: 2745518:HU722_RS10810
uniprot id: A0A8H9YTZ0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745518:HU722 RS20005
gene id: 2745518:HU722_RS20005
uniprot id: A0A8I0D0W3
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS08420
gene id: 2745518:HU722_RS08420
uniprot id: A0A8H9YX82
names: Similarity
messages: Belongs to the histone deacetylase family.

2745518:HU722 RS13975
gene id: 2745518:HU722_RS13975
uniprot id: A0A8H9YZZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

2745518:HU722 RS09950
gene id: 2745518:HU722_RS09950
uniprot id: A0A8H9YS10
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

2745518:HU722 RS19455
gene id: 2745518:HU722_RS19455
uniprot id: A0A8H9Z4J4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

2745518:HU722 RS08405
gene id: 2745518:HU722_RS08405
uniprot id: A0A8I0D0D5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS08880
gene id: 2745518:HU722_RS08880
uniprot id: A0A8H9YU08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS20530
gene id: 2745518:HU722_RS20530
uniprot id: A0A8I0D0H7
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

2745518:HU722 RS19695
gene id: 2745518:HU722_RS19695
uniprot id: A0A8H9Z329
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

2745518:HU722 RS12175
gene id: 2745518:HU722_RS12175
uniprot id: A0A8H9Z1U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

2745518:HU722 RS08440
gene id: 2745518:HU722_RS08440
uniprot id: A0A8H9YY94
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS02715
gene id: 2745518:HU722_RS02715
uniprot id: A0A8H9YN24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

2745518:HU722 RS12785
gene id: 2745518:HU722_RS12785
uniprot id: A0A8I0D1A1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS23935
gene id: 2745518:HU722_RS23935
uniprot id: A0A8H9Z156
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS00505
gene id: 2745518:HU722_RS00505
uniprot id: A0A8I0D0A8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS03485
gene id: 2745518:HU722_RS03485
uniprot id: A0A8I0CVR4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2745518:HU722 RS05350
gene id: 2745518:HU722_RS05350
uniprot id: A0A8H9Z2G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS25920
gene id: 2745518:HU722_RS25920
uniprot id: A0A8H9YPE7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS27600
gene id: 2745518:HU722_RS27600
uniprot id: A0A8H9YRK7
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

2745518:HU722 RS01115
gene id: 2745518:HU722_RS01115
uniprot id: A0A8H9YUY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

2745518:HU722 RS17825
gene id: 2745518:HU722_RS17825
uniprot id: A0A8I0CWC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

2745518:HU722 RS17995
gene id: 2745518:HU722_RS17995
uniprot id: A0A8H9YQ48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745518:HU722 RS19190
gene id: 2745518:HU722_RS19190
uniprot id: A0A8H9Z0C4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2745518:HU722 RS03730
gene id: 2745518:HU722_RS03730
uniprot id: A0A8I0CV09
names: Similarity
messages: Belongs to the peptidase C40 family.

2745518:HU722 RS25785
gene id: 2745518:HU722_RS25785
uniprot id: A0A8H9YQN2
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS03380
gene id: 2745518:HU722_RS03380
uniprot id: A0A8H9YNT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

2745518:HU722 RS07445
gene id: 2745518:HU722_RS07445
uniprot id: A0A8F4X0A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

2745518:HU722 RS11395
gene id: 2745518:HU722_RS11395
uniprot id: A0A8H9YV46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2745518:HU722 RS10570
gene id: 2745518:HU722_RS10570
uniprot id: A0A8H9YVM5
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

2745518:HU722 RS05990
gene id: 2745518:HU722_RS05990
uniprot id: A0A8I0CXS7
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS20395
gene id: 2745518:HU722_RS20395
uniprot id: A0A8I0D133
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

2745518:HU722 RS12510
gene id: 2745518:HU722_RS12510
uniprot id: A0A8H9Z2L9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS25600
gene id: 2745518:HU722_RS25600
uniprot id: A0A8I0CVZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

2745518:HU722 RS23380
gene id: 2745518:HU722_RS23380
uniprot id: A0A8H9YK29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

2745518:HU722 RS16635
gene id: 2745518:HU722_RS16635
uniprot id: A0A8H9Z4U0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

2745518:HU722 RS25720
gene id: 2745518:HU722_RS25720
uniprot id: A0A8H9YQZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

2745518:HU722 RS20825
gene id: 2745518:HU722_RS20825
uniprot id: A0A8H9YL38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

2745518:HU722 RS01510
gene id: 2745518:HU722_RS01510
uniprot id: A0A8H9Z2W0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2745518:HU722 RS20365
gene id: 2745518:HU722_RS20365
uniprot id: A0A8H9YZA0
names: Similarity
messages: Belongs to the cytochrome P450 family.

2745518:HU722 RS01970
gene id: 2745518:HU722_RS01970
uniprot id: A0A8I0D0J8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2745518:HU722 RS03020
gene id: 2745518:HU722_RS03020
uniprot id: A0A8F4WZI4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

2745518:HU722 RS12130
gene id: 2745518:HU722_RS12130
uniprot id: A0A8H9YZX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS25995
gene id: 2745518:HU722_RS25995
uniprot id: A0A8H9YPF6
names: Similarity
messages: Belongs to the peptidase S66 family.

2745518:HU722 RS26010
gene id: 2745518:HU722_RS26010
uniprot id: A0A8H9YQR0
names: Similarity
messages: Belongs to the UPF0250 family.

2745518:HU722 RS07165
gene id: 2745518:HU722_RS07165
uniprot id: A0A8I0CZ79
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745518:HU722 RS05880
gene id: 2745518:HU722_RS05880
uniprot id: A0A8H9YUF0
names: Similarity
messages: Belongs to the UPF0102 family.

2745518:HU722 RS06595
gene id: 2745518:HU722_RS06595
uniprot id: A0A8H9YXR8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2745518:HU722 RS07440
gene id: 2745518:HU722_RS07440
uniprot id: A0A8I0D1B1
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS19440
gene id: 2745518:HU722_RS19440
uniprot id: A0A8H9Z469
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS28030
gene id: 2745518:HU722_RS28030
uniprot id: A0A8H9YT19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS00030
gene id: 2745518:HU722_RS00030
uniprot id: A0A8H9YZ73
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

2745518:HU722 RS03365
gene id: 2745518:HU722_RS03365
uniprot id: A0A8H9YPM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

2745518:HU722 RS14150
gene id: 2745518:HU722_RS14150
uniprot id: A0A8I0D0W9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS03700
gene id: 2745518:HU722_RS03700
uniprot id: A0A8H9YMP0
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS11520
gene id: 2745518:HU722_RS11520
uniprot id: A0A8H9Z3I0
names: Similarity
messages: Belongs to the glutamine synthetase family.

2745518:HU722 RS06500
gene id: 2745518:HU722_RS06500
uniprot id: A0A8H9YV67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

2745518:HU722 RS26520
gene id: 2745518:HU722_RS26520
uniprot id: A0A8H9YPN1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2745518:HU722 RS21115
gene id: 2745518:HU722_RS21115
uniprot id: A0A8H9YL60
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

2745518:HU722 RS17840
gene id: 2745518:HU722_RS17840
uniprot id: A0A8H9YPZ5
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

2745518:HU722 RS00450
gene id: 2745518:HU722_RS00450
uniprot id: A0A8H9YXW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2745518:HU722 RS24540
gene id: 2745518:HU722_RS24540
uniprot id: A0A8H9Z0I3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

2745518:HU722 RS19945
gene id: 2745518:HU722_RS19945
uniprot id: A0A8H9YY73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS01390
gene id: 2745518:HU722_RS01390
uniprot id: A0A8H9YVE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 9 family.
messages: Periplasm

2745518:HU722 RS10835
gene id: 2745518:HU722_RS10835
uniprot id: A0A8I0CY81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2745518:HU722 RS02640
gene id: 2745518:HU722_RS02640
uniprot id: A0A8H9YN30
names: Function
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate.

2745518:HU722 RS28080
gene id: 2745518:HU722_RS28080
uniprot id: A0A8H9Z2B6
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

2745518:HU722 RS15235
gene id: 2745518:HU722_RS15235
uniprot id: A0A8I0CYX4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

2745518:HU722 RS18580
gene id: 2745518:HU722_RS18580
uniprot id: A0A8I0D375
names: Caution
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

2745518:HU722 RS03815
gene id: 2745518:HU722_RS03815
uniprot id: A0A8H9YPK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRR-containing bacterial E3 ligase family.
messages: Host cytoplasm
messages: Secreted

2745518:HU722 RS26760
gene id: 2745518:HU722_RS26760
uniprot id: A0A8H9YSK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

2745518:HU722 RS20280
gene id: 2745518:HU722_RS20280
uniprot id: A0A8H9YZU4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS06865
gene id: 2745518:HU722_RS06865
uniprot id: A0A8I0CZB9
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

2745518:HU722 RS06725
gene id: 2745518:HU722_RS06725
uniprot id: A0A8I0CYN9
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS22360
gene id: 2745518:HU722_RS22360
uniprot id: A0A8I0CTV3
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS24780
gene id: 2745518:HU722_RS24780
uniprot id: A0A8H9Z105
names: Similarity
messages: Belongs to the HIBADH-related family.

2745518:HU722 RS24095
gene id: 2745518:HU722_RS24095
uniprot id: A0A8H9Z2C2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS11470
gene id: 2745518:HU722_RS11470
uniprot id: A0A8H9YV37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

2745518:HU722 RS24180
gene id: 2745518:HU722_RS24180
uniprot id: A0A8F4WVU7
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

2745518:HU722 RS21330
gene id: 2745518:HU722_RS21330
uniprot id: A0A8F4WVU9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

2745518:HU722 RS12160
gene id: 2745518:HU722_RS12160
uniprot id: A0A8H9Z1D1
names: Similarity
messages: Belongs to the GSP L family.

2745518:HU722 RS23510
gene id: 2745518:HU722_RS23510
uniprot id: A0A8I0CUA7
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

2745518:HU722 RS06400
gene id: 2745518:HU722_RS06400
uniprot id: A0A8H9YU66
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

2745518:HU722 RS26785
gene id: 2745518:HU722_RS26785
uniprot id: A0A8I0CXM4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

2745518:HU722 RS27900
gene id: 2745518:HU722_RS27900
uniprot id: A0A8H9YRG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

2745518:HU722 RS02650
gene id: 2745518:HU722_RS02650
uniprot id: A0A8H9YMP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS03410
gene id: 2745518:HU722_RS03410
uniprot id: A0A8I0CVH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

2745518:HU722 RS25770
gene id: 2745518:HU722_RS25770
uniprot id: A0A8H9YPC7
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS21765
gene id: 2745518:HU722_RS21765
uniprot id: A0A8I0CUQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

2745518:HU722 RS00095
gene id: 2745518:HU722_RS00095
uniprot id: A0A8H9YYP9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2745518:HU722 RS17690
gene id: 2745518:HU722_RS17690
uniprot id: A0A8H9YQA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

2745518:HU722 RS06885
gene id: 2745518:HU722_RS06885
uniprot id: A0A8H9YX10
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

2745518:HU722 RS13640
gene id: 2745518:HU722_RS13640
uniprot id: A0A8H9YZ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS01750
gene id: 2745518:HU722_RS01750
uniprot id: A0A8H9Z0Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

2745518:HU722 RS10765
gene id: 2745518:HU722_RS10765
uniprot id: A0A8I0CY92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

2745518:HU722 RS18450
gene id: 2745518:HU722_RS18450
uniprot id: A0A8H9YQK6
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

2745518:HU722 RS27765
gene id: 2745518:HU722_RS27765
uniprot id: A0A8H9YQX4
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

2745518:HU722 RS21770
gene id: 2745518:HU722_RS21770
uniprot id: A0A8H9YIR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

2745518:HU722 RS10440
gene id: 2745518:HU722_RS10440
uniprot id: A0A8I0D329
names: Function
names: Similarity
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.

2745518:HU722 RS21505
gene id: 2745518:HU722_RS21505
uniprot id: A0A8H9YKV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

2745518:HU722 RS16365
gene id: 2745518:HU722_RS16365
uniprot id: A0A8I0CZL3
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS06185
gene id: 2745518:HU722_RS06185
uniprot id: A0A8H9YUJ1
names: Similarity
messages: Belongs to the PhoH family.

2745518:HU722 RS17810
gene id: 2745518:HU722_RS17810
uniprot id: A0A8H9YS94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

2745518:HU722 RS27745
gene id: 2745518:HU722_RS27745
uniprot id: A0A8H9YS68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

2745518:HU722 RS16165
gene id: 2745518:HU722_RS16165
uniprot id: A0A8H9YY35
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

2745518:HU722 RS26605
gene id: 2745518:HU722_RS26605
uniprot id: A0A8H9YQB3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2745518:HU722 RS25565
gene id: 2745518:HU722_RS25565
uniprot id: A0A8H9YQZ5
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

2745518:HU722 RS06930
gene id: 2745518:HU722_RS06930
uniprot id: A0A8I0CZW1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

2745518:HU722 RS18110
gene id: 2745518:HU722_RS18110
uniprot id: A0A8H9YSC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

2745518:HU722 RS29045
gene id: 2745518:HU722_RS29045
uniprot id: A0A8H9YMR4
names: Subcellular Location Annotation
messages: Cytoplasm

2745518:HU722 RS13725
gene id: 2745518:HU722_RS13725
uniprot id: A0A8H9Z3V5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2745518:HU722 RS25155
gene id: 2745518:HU722_RS25155
uniprot id: A0A8H9YP63
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS06905
gene id: 2745518:HU722_RS06905
uniprot id: A0A8H9YX14
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

2745518:HU722 RS23370
gene id: 2745518:HU722_RS23370
uniprot id: A0A8I0CV04
names: Subcellular Location Annotation
messages: Cytoplasm

2745518:HU722 RS14380
gene id: 2745518:HU722_RS14380
uniprot id: A0A8I0D0U3
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS02545
gene id: 2745518:HU722_RS02545
uniprot id: A0A8F4WYG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

2745518:HU722 RS05025
gene id: 2745518:HU722_RS05025
uniprot id: A0A8I0D2S1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

2745518:HU722 RS23215
gene id: 2745518:HU722_RS23215
uniprot id: A0A8I0CUP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YhhS family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS04885
gene id: 2745518:HU722_RS04885
uniprot id: A0A8H9Z2P9
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

2745518:HU722 RS20810
gene id: 2745518:HU722_RS20810
uniprot id: A0A8H9YJT6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

2745518:HU722 RS06850
gene id: 2745518:HU722_RS06850
uniprot id: A0A8H9YVY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS27665
gene id: 2745518:HU722_RS27665
uniprot id: A0A8H9YSR2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS21750
gene id: 2745518:HU722_RS21750
uniprot id: A0A8I0CTR6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745518:HU722 RS01145
gene id: 2745518:HU722_RS01145
uniprot id: A0A8I0CYJ9
names: Similarity
messages: Belongs to the sulfatase family.

2745518:HU722 RS09020
gene id: 2745518:HU722_RS09020
uniprot id: A0A8I0CWM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

2745518:HU722 RS00895
gene id: 2745518:HU722_RS00895
uniprot id: A0A8H9YUS9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS20030
gene id: 2745518:HU722_RS20030
uniprot id: A0A8H9YYP2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS23890
gene id: 2745518:HU722_RS23890
uniprot id: A0A8I0CTF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

2745518:HU722 RS26540
gene id: 2745518:HU722_RS26540
uniprot id: A0A8H9YRF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2745518:HU722 RS05700
gene id: 2745518:HU722_RS05700
uniprot id: A0A8H9YSR6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

2745518:HU722 RS16425
gene id: 2745518:HU722_RS16425
uniprot id: A0A8H9YWI2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS25060
gene id: 2745518:HU722_RS25060
uniprot id: A0A8I0CWC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

2745518:HU722 RS08310
gene id: 2745518:HU722_RS08310
uniprot id: A0A8I0CZ96
names: Function
messages: Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions.

2745518:HU722 RS01745
gene id: 2745518:HU722_RS01745
uniprot id: A0A8H9Z0Y4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2745518:HU722 RS08805
gene id: 2745518:HU722_RS08805
uniprot id: A0A8H9YXE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

2745518:HU722 RS26660
gene id: 2745518:HU722_RS26660
uniprot id: A0A8I0CWV4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2745518:HU722 RS02825
gene id: 2745518:HU722_RS02825
uniprot id: A0A8I0CUL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2745518:HU722 RS22750
gene id: 2745518:HU722_RS22750
uniprot id: A0A8I0CU09
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

2745518:HU722 RS02925
gene id: 2745518:HU722_RS02925
uniprot id: A0A8F4WYL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

2745518:HU722 RS01620
gene id: 2745518:HU722_RS01620
uniprot id: A0A8I0D1S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

2745518:HU722 RS15465
gene id: 2745518:HU722_RS15465
uniprot id: A0A8I0CYZ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

2745518:HU722 RS03930
gene id: 2745518:HU722_RS03930
uniprot id: A0A8H9YM74
names: Similarity
messages: Belongs to the CobH/CbiC family.

2745518:HU722 RS23535
gene id: 2745518:HU722_RS23535
uniprot id: A0A8H9YK74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

2745518:HU722 RS00475
gene id: 2745518:HU722_RS00475
uniprot id: A0A8H9YZD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS09805
gene id: 2745518:HU722_RS09805
uniprot id: A0A8H9YRR6
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

2745518:HU722 RS14645
gene id: 2745518:HU722_RS14645
uniprot id: A0A8H9Z2R4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

2745518:HU722 RS11100
gene id: 2745518:HU722_RS11100
uniprot id: A0A8H9YUS3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS04005
gene id: 2745518:HU722_RS04005
uniprot id: A0A8H9YM68
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745518:HU722 RS14545
gene id: 2745518:HU722_RS14545
uniprot id: A0A8H9Z178
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

2745518:HU722 RS00165
gene id: 2745518:HU722_RS00165
uniprot id: A0A8H9YY71
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

2745518:HU722 RS05370
gene id: 2745518:HU722_RS05370
uniprot id: A0A8H9Z1M2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

2745518:HU722 RS20025
gene id: 2745518:HU722_RS20025
uniprot id: A0A8H9YY96
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS09605
gene id: 2745518:HU722_RS09605
uniprot id: A0A8I0CX39
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

2745518:HU722 RS08295
gene id: 2745518:HU722_RS08295
uniprot id: A0A8H9YZA1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745518:HU722 RS19180
gene id: 2745518:HU722_RS19180
uniprot id: A0A8H9Z0T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2745518:HU722 RS11935
gene id: 2745518:HU722_RS11935
uniprot id: A0A8H9Z1A1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS23350
gene id: 2745518:HU722_RS23350
uniprot id: A0A8I0CT97
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2745518:HU722 RS23715
gene id: 2745518:HU722_RS23715
uniprot id: A0A8H9YN51
names: Subcellular Location Annotation
messages: Cell inner membrane

2745518:HU722 RS05300
gene id: 2745518:HU722_RS05300
uniprot id: A0A8I0D2P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS18295
gene id: 2745518:HU722_RS18295
uniprot id: A0A8H9YQ97
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS10445
gene id: 2745518:HU722_RS10445
uniprot id: A0A8I0D2J6
names: Similarity
messages: Belongs to the SsuE family.

2745518:HU722 RS11055
gene id: 2745518:HU722_RS11055
uniprot id: A0A8I0CYN8
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

2745518:HU722 RS04115
gene id: 2745518:HU722_RS04115
uniprot id: A0A8H9YPF4
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS09350
gene id: 2745518:HU722_RS09350
uniprot id: A0A8H9YS91
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS23575
gene id: 2745518:HU722_RS23575
uniprot id: A0A8H9YN74
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS19220
gene id: 2745518:HU722_RS19220
uniprot id: A0A8I0D1A5
names: Subcellular Location Annotation
messages: Cytoplasm

2745518:HU722 RS21295
gene id: 2745518:HU722_RS21295
uniprot id: A0A8I0CS88
names: Similarity
messages: Belongs to the DEAD box helicase family.

2745518:HU722 RS26955
gene id: 2745518:HU722_RS26955
uniprot id: A0A8F4WX31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

2745518:HU722 RS27395
gene id: 2745518:HU722_RS27395
uniprot id: A0A8I0CXD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS08160
gene id: 2745518:HU722_RS08160
uniprot id: A0A8I0CZV7
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS21375
gene id: 2745518:HU722_RS21375
uniprot id: A0A8I0CTI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

2745518:HU722 RS00995
gene id: 2745518:HU722_RS00995
uniprot id: A0A8I0CYL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

2745518:HU722 RS12820
gene id: 2745518:HU722_RS12820
uniprot id: A0A8H9Z0V1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745518:HU722 RS00765
gene id: 2745518:HU722_RS00765
uniprot id: A0A8I0CZ36
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

2745518:HU722 RS00430
gene id: 2745518:HU722_RS00430
uniprot id: A0A8I0D088
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS16895
gene id: 2745518:HU722_RS16895
uniprot id: A0A8H9Z3Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS01175
gene id: 2745518:HU722_RS01175
uniprot id: A0A8H9YVZ5
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS02030
gene id: 2745518:HU722_RS02030
uniprot id: A0A8H9YXL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

2745518:HU722 RS22430
gene id: 2745518:HU722_RS22430
uniprot id: A0A8I0CU26
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

2745518:HU722 RS02240
gene id: 2745518:HU722_RS02240
uniprot id: A0A8H9YZ02
names: Similarity
messages: Belongs to the thioesterase PaaI family.

2745518:HU722 RS23745
gene id: 2745518:HU722_RS23745
uniprot id: A0A8I0CUS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS24790
gene id: 2745518:HU722_RS24790
uniprot id: A0A8H9Z290
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS20935
gene id: 2745518:HU722_RS20935
uniprot id: A0A8I0CU61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

2745518:HU722 RS28515
gene id: 2745518:HU722_RS28515
uniprot id: A0A8H9Z2L4
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

2745518:HU722 RS03185
gene id: 2745518:HU722_RS03185
uniprot id: A0A8I0CVI8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

2745518:HU722 RS17855
gene id: 2745518:HU722_RS17855
uniprot id: A0A8H9YQM5
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

2745518:HU722 RS24960
gene id: 2745518:HU722_RS24960
uniprot id: A0A8H9YQ74
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

2745518:HU722 RS28470
gene id: 2745518:HU722_RS28470
uniprot id: A0A8H9Z123
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS26830
gene id: 2745518:HU722_RS26830
uniprot id: A0A8H9YT20
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

2745518:HU722 RS00945
gene id: 2745518:HU722_RS00945
uniprot id: A0A8H9YWP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

2745518:HU722 RS09725
gene id: 2745518:HU722_RS09725
uniprot id: A0A8H9YS39
names: Similarity
messages: Belongs to the type III secretion exporter family.

2745518:HU722 RS00455
gene id: 2745518:HU722_RS00455
uniprot id: A0A8H9YXY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

2745518:HU722 RS12635
gene id: 2745518:HU722_RS12635
uniprot id: A0A8I0D0P7
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

2745518:HU722 RS03435
gene id: 2745518:HU722_RS03435
uniprot id: A0A8H9YNG4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

2745518:HU722 RS11625
gene id: 2745518:HU722_RS11625
uniprot id: A0A8I0D273
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

2745518:HU722 RS05425
gene id: 2745518:HU722_RS05425
uniprot id: A0A8H9YUU1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745518:HU722 RS22575
gene id: 2745518:HU722_RS22575
uniprot id: A0A8I0CSX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

2745518:HU722 RS11855
gene id: 2745518:HU722_RS11855
uniprot id: A0A8H9Z1D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

2745518:HU722 RS05795
gene id: 2745518:HU722_RS05795
uniprot id: A0A8F4WZI9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

2745518:HU722 RS01005
gene id: 2745518:HU722_RS01005
uniprot id: A0A8F4X2Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

2745518:HU722 RS27990
gene id: 2745518:HU722_RS27990
uniprot id: A0A8H9YQU2
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS03390
gene id: 2745518:HU722_RS03390
uniprot id: A0A8H9YMT2
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

2745518:HU722 RS07515
gene id: 2745518:HU722_RS07515
uniprot id: A0A8I0D1B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2745518:HU722 RS23110
gene id: 2745518:HU722_RS23110
uniprot id: A0A8H9YMY2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS13565
gene id: 2745518:HU722_RS13565
uniprot id: A0A8H9YZ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS02375
gene id: 2745518:HU722_RS02375
uniprot id: A0A8H9YZH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

2745518:HU722 RS05935
gene id: 2745518:HU722_RS05935
uniprot id: A0A8H9YSU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

2745518:HU722 RS02730
gene id: 2745518:HU722_RS02730
uniprot id: A0A8I0CVW8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2745518:HU722 RS05360
gene id: 2745518:HU722_RS05360
uniprot id: A0A8H9Z1N1
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

2745518:HU722 RS26915
gene id: 2745518:HU722_RS26915
uniprot id: A0A8H9YRX0
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

2745518:HU722 RS18635
gene id: 2745518:HU722_RS18635
uniprot id: A0A8I0D1Y4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

2745518:HU722 RS26845
gene id: 2745518:HU722_RS26845
uniprot id: A0A8H9YRK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS18320
gene id: 2745518:HU722_RS18320
uniprot id: A0A8H9YRU5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745518:HU722 RS18310
gene id: 2745518:HU722_RS18310
uniprot id: A0A8H9YRI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRR-containing bacterial E3 ligase family.
messages: Host cytoplasm
messages: Secreted

2745518:HU722 RS09205
gene id: 2745518:HU722_RS09205
uniprot id: A0A8H9YSA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

2745518:HU722 RS19990
gene id: 2745518:HU722_RS19990
uniprot id: A0A8I0CZS1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS02560
gene id: 2745518:HU722_RS02560
uniprot id: A0A8H9YYE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

2745518:HU722 RS19610
gene id: 2745518:HU722_RS19610
uniprot id: A0A8H9Z2B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

2745518:HU722 RS23055
gene id: 2745518:HU722_RS23055
uniprot id: A0A8I0CU74
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

2745518:HU722 RS20950
gene id: 2745518:HU722_RS20950
uniprot id: A0A8H9YI71
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2745518:HU722 RS08375
gene id: 2745518:HU722_RS08375
uniprot id: A0A8H9YZB4
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS10260
gene id: 2745518:HU722_RS10260
uniprot id: A0A8H9Z2S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS08710
gene id: 2745518:HU722_RS08710
uniprot id: A0A8I0D0F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Sulfur carrier protein which probably makes part of a sulfur-relay system.

2745518:HU722 RS05955
gene id: 2745518:HU722_RS05955
uniprot id: A0A8H9YUM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

2745518:HU722 RS21460
gene id: 2745518:HU722_RS21460
uniprot id: A0A8I0CUN5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

2745518:HU722 RS13375
gene id: 2745518:HU722_RS13375
uniprot id: A0A8I0D0J5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

2745518:HU722 RS09335
gene id: 2745518:HU722_RS09335
uniprot id: A0A8H9YT73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

2745518:HU722 RS21185
gene id: 2745518:HU722_RS21185
uniprot id: A0A8H9YK40
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

2745518:HU722 RS07370
gene id: 2745518:HU722_RS07370
uniprot id: A0A8H9YVR6
names: Similarity
messages: Belongs to the SufE family.

2745518:HU722 RS27120
gene id: 2745518:HU722_RS27120
uniprot id: A0A8H9YS83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

2745518:HU722 RS13020
gene id: 2745518:HU722_RS13020
uniprot id: A0A8H9Z1W4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2745518:HU722 RS10725
gene id: 2745518:HU722_RS10725
uniprot id: A0A8H9YUX4
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS17770
gene id: 2745518:HU722_RS17770
uniprot id: A0A8H9YQ19
names: Similarity
messages: Belongs to the ArsC family.

2745518:HU722 RS23840
gene id: 2745518:HU722_RS23840
uniprot id: A0A8H9YKP8
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS03215
gene id: 2745518:HU722_RS03215
uniprot id: A0A8H9YPP0
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

2745518:HU722 RS09540
gene id: 2745518:HU722_RS09540
uniprot id: A0A8I0CWI9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS20660
gene id: 2745518:HU722_RS20660
uniprot id: A0A8H9YIL4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2745518:HU722 RS25620
gene id: 2745518:HU722_RS25620
uniprot id: A0A8H9YPB3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

2745518:HU722 RS23570
gene id: 2745518:HU722_RS23570
uniprot id: A0A8H9YLY2
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

2745518:HU722 RS00590
gene id: 2745518:HU722_RS00590
uniprot id: A0A8H9YV39
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

2745518:HU722 RS17960
gene id: 2745518:HU722_RS17960
uniprot id: A0A8H9YSA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745518:HU722 RS24595
gene id: 2745518:HU722_RS24595
uniprot id: A0A8I0D1I9
names: Similarity
messages: Belongs to the glutathione peroxidase family.

2745518:HU722 RS26975
gene id: 2745518:HU722_RS26975
uniprot id: A0A8H9YSS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

2745518:HU722 RS18965
gene id: 2745518:HU722_RS18965
uniprot id: A0A8H9YZQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS02525
gene id: 2745518:HU722_RS02525
uniprot id: A0A8I0D009
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

2745518:HU722 RS11145
gene id: 2745518:HU722_RS11145
uniprot id: A0A8I0CXJ8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

2745518:HU722 RS21880
gene id: 2745518:HU722_RS21880
uniprot id: A0A8H9YMI0
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

2745518:HU722 RS09670
gene id: 2745518:HU722_RS09670
uniprot id: A0A8I0CXQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS21160
gene id: 2745518:HU722_RS21160
uniprot id: A0A8I0CU80
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

2745518:HU722 RS24985
gene id: 2745518:HU722_RS24985
uniprot id: A0A8I0CWB7
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

2745518:HU722 RS11125
gene id: 2745518:HU722_RS11125
uniprot id: A0A8I0CYS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS28535
gene id: 2745518:HU722_RS28535
uniprot id: A0A8H9Z2A5
names: Similarity
messages: Belongs to the UPF0178 family.

2745518:HU722 RS25165
gene id: 2745518:HU722_RS25165
uniprot id: A0A8H9YPI0
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

2745518:HU722 RS23680
gene id: 2745518:HU722_RS23680
uniprot id: A0A8H9YKL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

2745518:HU722 RS11975
gene id: 2745518:HU722_RS11975
uniprot id: A0A8I0D1S8
names: Similarity
messages: Belongs to the hyi family.

2745518:HU722 RS00005
gene id: 2745518:HU722_RS00005
uniprot id: A0A8H9YXQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

2745518:HU722 RS23435
gene id: 2745518:HU722_RS23435
uniprot id: A0A8I0CUA1
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

2745518:HU722 RS23915
gene id: 2745518:HU722_RS23915
uniprot id: A0A8I0D1F7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

2745518:HU722 RS05225
gene id: 2745518:HU722_RS05225
uniprot id: A0A8I0D239
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745518:HU722 RS12425
gene id: 2745518:HU722_RS12425
uniprot id: A0A8H9Z220
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS04220
gene id: 2745518:HU722_RS04220
uniprot id: A0A8H9YMS4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS28310
gene id: 2745518:HU722_RS28310
uniprot id: A0A8H9Z1I5
names: Similarity
messages: Belongs to the GSP E family.

2745518:HU722 RS11010
gene id: 2745518:HU722_RS11010
uniprot id: A0A8H9YVX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

2745518:HU722 RS09430
gene id: 2745518:HU722_RS09430
uniprot id: A0A8H9YRV1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

2745518:HU722 RS27125
gene id: 2745518:HU722_RS27125
uniprot id: A0A8H9YTD9
names: Subcellular Location Annotation
messages: Cytoplasm

2745518:HU722 RS22735
gene id: 2745518:HU722_RS22735
uniprot id: A0A8H9YMX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2745518:HU722 RS02130
gene id: 2745518:HU722_RS02130
uniprot id: A0A8I0D0I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS15800
gene id: 2745518:HU722_RS15800
uniprot id: A0A8H9YWR4
names: Similarity
messages: Belongs to the proline racemase family.

2745518:HU722 RS02830
gene id: 2745518:HU722_RS02830
uniprot id: A0A8H9YPX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2745518:HU722 RS05105
gene id: 2745518:HU722_RS05105
uniprot id: A0A8I0D3B5
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

2745518:HU722 RS05805
gene id: 2745518:HU722_RS05805
uniprot id: A0A8H9YUZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

2745518:HU722 RS05525
gene id: 2745518:HU722_RS05525
uniprot id: A0A8I0CXQ0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

2745518:HU722 RS26030
gene id: 2745518:HU722_RS26030
uniprot id: A0A8H9YQM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

2745518:HU722 RS23880
gene id: 2745518:HU722_RS23880
uniprot id: A0A8H9YM28
names: Similarity
messages: Belongs to the threonine synthase family.

2745518:HU722 RS26900
gene id: 2745518:HU722_RS26900
uniprot id: A0A8H9YST2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

2745518:HU722 RS28455
gene id: 2745518:HU722_RS28455
uniprot id: A0A8H9Z266
names: Similarity
messages: Belongs to the thioredoxin family.

2745518:HU722 RS02630
gene id: 2745518:HU722_RS02630
uniprot id: A0A8H9YP46
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

2745518:HU722 RS23100
gene id: 2745518:HU722_RS23100
uniprot id: A0A8H9YML5
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

2745518:HU722 RS22310
gene id: 2745518:HU722_RS22310
uniprot id: A0A8H9YK80
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

2745518:HU722 RS03820
gene id: 2745518:HU722_RS03820
uniprot id: A0A8H9YNB3
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

2745518:HU722 RS20135
gene id: 2745518:HU722_RS20135
uniprot id: A0A8H9Z0B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

2745518:HU722 RS00075
gene id: 2745518:HU722_RS00075
uniprot id: A0A8H9YXQ5
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS11680
gene id: 2745518:HU722_RS11680
uniprot id: A0A8H9Z448
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

2745518:HU722 RS18615
gene id: 2745518:HU722_RS18615
uniprot id: A0A8H9Z4C1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS21885
gene id: 2745518:HU722_RS21885
uniprot id: A0A8H9YL21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

2745518:HU722 RS03125
gene id: 2745518:HU722_RS03125
uniprot id: A0A8I0CUJ3
names: Similarity
messages: Belongs to the thioredoxin family.

2745518:HU722 RS16485
gene id: 2745518:HU722_RS16485
uniprot id: A0A8H9YXJ3
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

2745518:HU722 RS27905
gene id: 2745518:HU722_RS27905
uniprot id: A0A8H9YR55
names: Similarity
messages: Belongs to the peptidase M16 family.

2745518:HU722 RS01505
gene id: 2745518:HU722_RS01505
uniprot id: A0A8H9Z2Z0
names: Similarity
messages: Belongs to the peptidase M16 family.

2745518:HU722 RS10985
gene id: 2745518:HU722_RS10985
uniprot id: A0A8I0CY70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopC family.
messages: Involved in copper resistance.
messages: Periplasm

2745518:HU722 RS08590
gene id: 2745518:HU722_RS08590
uniprot id: A0A8H9YYB7
names: Similarity
messages: Belongs to the UPF0260 family.

2745518:HU722 RS01565
gene id: 2745518:HU722_RS01565
uniprot id: A0A8H9Z4I2
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

2745518:HU722 RS07335
gene id: 2745518:HU722_RS07335
uniprot id: A0A8H9YXY5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

2745518:HU722 RS07205
gene id: 2745518:HU722_RS07205
uniprot id: A0A8H9YW77
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS19210
gene id: 2745518:HU722_RS19210
uniprot id: A0A8H9YYP3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS00635
gene id: 2745518:HU722_RS00635
uniprot id: A0A8F4WXY8
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

2745518:HU722 RS11230
gene id: 2745518:HU722_RS11230
uniprot id: A0A8H9YUN8
names: Similarity
messages: Belongs to the glutamine synthetase family.

2745518:HU722 RS14330
gene id: 2745518:HU722_RS14330
uniprot id: A0A8H9YYI5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

2745518:HU722 RS26120
gene id: 2745518:HU722_RS26120
uniprot id: A0A8I0CW42
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2745518:HU722 RS06135
gene id: 2745518:HU722_RS06135
uniprot id: A0A8I0CXU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AlgX family.
messages: Periplasm

2745518:HU722 RS07375
gene id: 2745518:HU722_RS07375
uniprot id: A0A8I0CZT4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

2745518:HU722 RS19970
gene id: 2745518:HU722_RS19970
uniprot id: A0A8H9YZQ8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

2745518:HU722 RS10455
gene id: 2745518:HU722_RS10455
uniprot id: A0A8I0D1T0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS09470
gene id: 2745518:HU722_RS09470
uniprot id: A0A8H9YTS1
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

2745518:HU722 RS00385
gene id: 2745518:HU722_RS00385
uniprot id: A0A8H9YXX4
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

2745518:HU722 RS02775
gene id: 2745518:HU722_RS02775
uniprot id: A0A8H9YPE4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS17370
gene id: 2745518:HU722_RS17370
uniprot id: A0A8H9YPW0
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

2745518:HU722 RS26740
gene id: 2745518:HU722_RS26740
uniprot id: A0A8H9YSF1
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS27815
gene id: 2745518:HU722_RS27815
uniprot id: A0A8H9YSP3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

2745518:HU722 RS14570
gene id: 2745518:HU722_RS14570
uniprot id: A0A8H9Z2P8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2745518:HU722 RS21730
gene id: 2745518:HU722_RS21730
uniprot id: A0A8H9YMG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

2745518:HU722 RS20440
gene id: 2745518:HU722_RS20440
uniprot id: A0A8H9YZB3
names: Similarity
messages: Belongs to the GST superfamily.

2745518:HU722 RS04815
gene id: 2745518:HU722_RS04815
uniprot id: A0A8H9Z1G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SctL stator family.
messages: Cytoplasm

2745518:HU722 RS26460
gene id: 2745518:HU722_RS26460
uniprot id: A0A8H9YQY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

2745518:HU722 RS28605
gene id: 2745518:HU722_RS28605
uniprot id: A0A8H9YXN3
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

2745518:HU722 RS24445
gene id: 2745518:HU722_RS24445
uniprot id: A0A8I0D1Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS12080
gene id: 2745518:HU722_RS12080
uniprot id: A0A8H9Z1H0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS25040
gene id: 2745518:HU722_RS25040
uniprot id: A0A8H9YRA2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

2745518:HU722 RS04980
gene id: 2745518:HU722_RS04980
uniprot id: A0A8H9Z0Z4
names: Function
messages: Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions.

2745518:HU722 RS09255
gene id: 2745518:HU722_RS09255
uniprot id: A0A8H9YSR7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

2745518:HU722 RS08745
gene id: 2745518:HU722_RS08745
uniprot id: A0A8H9YZ10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

2745518:HU722 RS16195
gene id: 2745518:HU722_RS16195
uniprot id: A0A8H9YWL6
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

2745518:HU722 RS07630
gene id: 2745518:HU722_RS07630
uniprot id: A0A8H9Z1Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2745518:HU722 RS05550
gene id: 2745518:HU722_RS05550
uniprot id: A0A8H9YSP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

2745518:HU722 RS24865
gene id: 2745518:HU722_RS24865
uniprot id: A0A8H9YQA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

2745518:HU722 RS07500
gene id: 2745518:HU722_RS07500
uniprot id: A0A8H9Z3N5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS13985
gene id: 2745518:HU722_RS13985
uniprot id: A0A8I0D0A0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS18010
gene id: 2745518:HU722_RS18010
uniprot id: A0A8H9YRC9
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS05925
gene id: 2745518:HU722_RS05925
uniprot id: A0A8I0CYD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

2745518:HU722 RS06490
gene id: 2745518:HU722_RS06490
uniprot id: A0A8H9YVA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

2745518:HU722 RS13960
gene id: 2745518:HU722_RS13960
uniprot id: A0A8H9YZF9
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

2745518:HU722 RS24235
gene id: 2745518:HU722_RS24235
uniprot id: A0A8H9Z254
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

2745518:HU722 RS01785
gene id: 2745518:HU722_RS01785
uniprot id: A0A8H9Z2V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPS (TC 1.B.20) family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS27565
gene id: 2745518:HU722_RS27565
uniprot id: A0A8I0CWA2
names: Function
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

2745518:HU722 RS12875
gene id: 2745518:HU722_RS12875
uniprot id: A0A8H9Z224
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

2745518:HU722 RS03270
gene id: 2745518:HU722_RS03270
uniprot id: A0A8I0CV41
names: Similarity
messages: Belongs to the NodU/CmcH family.

2745518:HU722 RS27635
gene id: 2745518:HU722_RS27635
uniprot id: A0A8I0CWU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

2745518:HU722 RS18240
gene id: 2745518:HU722_RS18240
uniprot id: A0A8H9YRX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

2745518:HU722 RS18875
gene id: 2745518:HU722_RS18875
uniprot id: A0A8H9Z0X5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS27580
gene id: 2745518:HU722_RS27580
uniprot id: A0A8H9YT81
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS19840
gene id: 2745518:HU722_RS19840
uniprot id: A0A8H9Z2F6
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS10285
gene id: 2745518:HU722_RS10285
uniprot id: A0A8H9Z2D4
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS09570
gene id: 2745518:HU722_RS09570
uniprot id: A0A8H9YST6
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

2745518:HU722 RS00555
gene id: 2745518:HU722_RS00555
uniprot id: A0A8I0CY15
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS21780
gene id: 2745518:HU722_RS21780
uniprot id: A0A8H9YJQ0
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

2745518:HU722 RS02855
gene id: 2745518:HU722_RS02855
uniprot id: A0A8H9YP05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

2745518:HU722 RS12145
gene id: 2745518:HU722_RS12145
uniprot id: A0A8H9Z0A9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

2745518:HU722 RS09770
gene id: 2745518:HU722_RS09770
uniprot id: A0A8H9YTN5
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

2745518:HU722 RS18470
gene id: 2745518:HU722_RS18470
uniprot id: A0A8H9YS09
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

2745518:HU722 RS02105
gene id: 2745518:HU722_RS02105
uniprot id: A0A8H9YXY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS19145
gene id: 2745518:HU722_RS19145
uniprot id: A0A8I0D144
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS20160
gene id: 2745518:HU722_RS20160
uniprot id: A0A8I0D0G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

2745518:HU722 RS19650
gene id: 2745518:HU722_RS19650
uniprot id: A0A8I0D225
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

2745518:HU722 RS05965
gene id: 2745518:HU722_RS05965
uniprot id: A0A8H9YV10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

2745518:HU722 RS05155
gene id: 2745518:HU722_RS05155
uniprot id: A0A8H9Z3P5
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS22480
gene id: 2745518:HU722_RS22480
uniprot id: A0A8H9YM08
names: Similarity
messages: Belongs to the peptidase S49 family.

2745518:HU722 RS26145
gene id: 2745518:HU722_RS26145
uniprot id: A0A8H9YPI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS26510
gene id: 2745518:HU722_RS26510
uniprot id: A0A8I0CWU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2745518:HU722 RS05945
gene id: 2745518:HU722_RS05945
uniprot id: A0A8H9YTD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

2745518:HU722 RS09250
gene id: 2745518:HU722_RS09250
uniprot id: A0A8H9YTW2
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS27780
gene id: 2745518:HU722_RS27780
uniprot id: A0A8F4WX55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

2745518:HU722 RS13570
gene id: 2745518:HU722_RS13570
uniprot id: A0A8H9YZI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS18980
gene id: 2745518:HU722_RS18980
uniprot id: A0A8H9YYT0
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

2745518:HU722 RS17890
gene id: 2745518:HU722_RS17890
uniprot id: A0A8I0CVT5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

2745518:HU722 RS13175
gene id: 2745518:HU722_RS13175
uniprot id: A0A8H9YYG6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

2745518:HU722 RS13590
gene id: 2745518:HU722_RS13590
uniprot id: A0A8H9YZI8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

2745518:HU722 RS11540
gene id: 2745518:HU722_RS11540
uniprot id: A0A8H9Z3T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS10685
gene id: 2745518:HU722_RS10685
uniprot id: A0A8I0CY93
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

2745518:HU722 RS20975
gene id: 2745518:HU722_RS20975
uniprot id: A0A8H9YL78
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

2745518:HU722 RS02090
gene id: 2745518:HU722_RS02090
uniprot id: A0A8H9YZ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

2745518:HU722 RS06910
gene id: 2745518:HU722_RS06910
uniprot id: A0A8H9YWB8
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

2745518:HU722 RS21060
gene id: 2745518:HU722_RS21060
uniprot id: A0A8H9YKF8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

2745518:HU722 RS07490
gene id: 2745518:HU722_RS07490
uniprot id: A0A8H9Z345
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

2745518:HU722 RS27655
gene id: 2745518:HU722_RS27655
uniprot id: A0A8H9YT74
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS10195
gene id: 2745518:HU722_RS10195
uniprot id: A0A8I0D325
names: Similarity
messages: Belongs to the GST superfamily.

2745518:HU722 RS16665
gene id: 2745518:HU722_RS16665
uniprot id: A0A8H9Z389
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS14400
gene id: 2745518:HU722_RS14400
uniprot id: A0A8H9YY45
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS20760
gene id: 2745518:HU722_RS20760
uniprot id: A0A8H9YM29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

2745518:HU722 RS16935
gene id: 2745518:HU722_RS16935
uniprot id: A0A8H9Z1Q4
names: Similarity
messages: Belongs to the peptidase S49 family.

2745518:HU722 RS02110
gene id: 2745518:HU722_RS02110
uniprot id: A0A8H9YXL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS06965
gene id: 2745518:HU722_RS06965
uniprot id: A0A8H9YY24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

2745518:HU722 RS16315
gene id: 2745518:HU722_RS16315
uniprot id: A0A8H9YYM5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS01100
gene id: 2745518:HU722_RS01100
uniprot id: A0A8H9YW09
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

2745518:HU722 RS13180
gene id: 2745518:HU722_RS13180
uniprot id: A0A8H9YYG7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

2745518:HU722 RS12860
gene id: 2745518:HU722_RS12860
uniprot id: A0A8I0D197
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

2745518:HU722 RS18925
gene id: 2745518:HU722_RS18925
uniprot id: A0A8I0D0R9
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

2745518:HU722 RS14100
gene id: 2745518:HU722_RS14100
uniprot id: A0A8H9YYY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

2745518:HU722 RS01845
gene id: 2745518:HU722_RS01845
uniprot id: A0A8I0D2B6
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS06795
gene id: 2745518:HU722_RS06795
uniprot id: A0A8I0CZA5
names: Similarity
messages: Belongs to the MipA/OmpV family.

2745518:HU722 RS08035
gene id: 2745518:HU722_RS08035
uniprot id: A0A8H9YX48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

2745518:HU722 RS00380
gene id: 2745518:HU722_RS00380
uniprot id: A0A8H9YXX3
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

2745518:HU722 RS21755
gene id: 2745518:HU722_RS21755
uniprot id: A0A8I0CTL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

2745518:HU722 RS24460
gene id: 2745518:HU722_RS24460
uniprot id: A0A8I0D242
names: Caution
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS28045
gene id: 2745518:HU722_RS28045
uniprot id: A0A8H9Z361
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

2745518:HU722 RS11090
gene id: 2745518:HU722_RS11090
uniprot id: A0A8H9YV84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

2745518:HU722 RS13275
gene id: 2745518:HU722_RS13275
uniprot id: A0A8H9Z006
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS07680
gene id: 2745518:HU722_RS07680
uniprot id: A0A8H9Z381
names: Similarity
messages: Belongs to the UPF0225 family.

2745518:HU722 RS28140
gene id: 2745518:HU722_RS28140
uniprot id: A0A8I0D2I2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2745518:HU722 RS08300
gene id: 2745518:HU722_RS08300
uniprot id: A0A8H9YY62
names: Similarity
messages: Belongs to the RseA family.

2745518:HU722 RS24435
gene id: 2745518:HU722_RS24435
uniprot id: A0A8H9Z039
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

2745518:HU722 RS10595
gene id: 2745518:HU722_RS10595
uniprot id: A0A8H9YTX6
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

2745518:HU722 RS19950
gene id: 2745518:HU722_RS19950
uniprot id: A0A8H9YY83
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS26560
gene id: 2745518:HU722_RS26560
uniprot id: A0A8H9YRS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2745518:HU722 RS26455
gene id: 2745518:HU722_RS26455
uniprot id: A0A8H9YQ89
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS20790
gene id: 2745518:HU722_RS20790
uniprot id: A0A8I0CUJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

2745518:HU722 RS28065
gene id: 2745518:HU722_RS28065
uniprot id: A0A8I0D2H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS27550
gene id: 2745518:HU722_RS27550
uniprot id: A0A8I0CXC8
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
messages: Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.

2745518:HU722 RS26155
gene id: 2745518:HU722_RS26155
uniprot id: A0A8H9YQ41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

2745518:HU722 RS25035
gene id: 2745518:HU722_RS25035
uniprot id: A0A8H9YQ92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2745518:HU722 RS28615
gene id: 2745518:HU722_RS28615
uniprot id: A0A8H9YY25
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

2745518:HU722 RS19480
gene id: 2745518:HU722_RS19480
uniprot id: A0A8I0D354
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS08335
gene id: 2745518:HU722_RS08335
uniprot id: A0A8H9YX73
names: Subcellular Location Annotation
messages: Cytoplasm

2745518:HU722 RS25080
gene id: 2745518:HU722_RS25080
uniprot id: A0A8H9YP60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

2745518:HU722 RS24250
gene id: 2745518:HU722_RS24250
uniprot id: A0A8H9Z1P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

2745518:HU722 RS20520
gene id: 2745518:HU722_RS20520
uniprot id: A0A8H9Z0E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

2745518:HU722 RS06240
gene id: 2745518:HU722_RS06240
uniprot id: A0A8H9YT72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS03645
gene id: 2745518:HU722_RS03645
uniprot id: A0A8I0CVF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

2745518:HU722 RS03680
gene id: 2745518:HU722_RS03680
uniprot id: A0A8H9YNV6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS22475
gene id: 2745518:HU722_RS22475
uniprot id: A0A8H9YMD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

2745518:HU722 RS23525
gene id: 2745518:HU722_RS23525
uniprot id: A0A8I0CV16
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2745518:HU722 RS20215
gene id: 2745518:HU722_RS20215
uniprot id: A0A8H9YZ88
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS04625
gene id: 2745518:HU722_RS04625
uniprot id: A0A8I0D2T6
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

2745518:HU722 RS24770
gene id: 2745518:HU722_RS24770
uniprot id: A0A8H9Z0L7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Cyclase 1 superfamily. KynB family.
messages: Binds 2 zinc ions per subunit.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
messages: Homodimer.

2745518:HU722 RS17875
gene id: 2745518:HU722_RS17875
uniprot id: A0A8H9YSB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

2745518:HU722 RS17850
gene id: 2745518:HU722_RS17850
uniprot id: A0A8H9YQD2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

2745518:HU722 RS05165
gene id: 2745518:HU722_RS05165
uniprot id: A0A8H9Z3Y3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

2745518:HU722 RS03960
gene id: 2745518:HU722_RS03960
uniprot id: A0A8I0CUC5
names: Similarity
messages: Belongs to the GARS family.

2745518:HU722 RS18410
gene id: 2745518:HU722_RS18410
uniprot id: A0A8H9YSH7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. PhnX family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Involved in phosphonate degradation.

2745518:HU722 RS06785
gene id: 2745518:HU722_RS06785
uniprot id: A0A8I0CZS4
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS18160
gene id: 2745518:HU722_RS18160
uniprot id: A0A8H9YRG0
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

2745518:HU722 RS11670
gene id: 2745518:HU722_RS11670
uniprot id: A0A8H9Z3J9
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS11165
gene id: 2745518:HU722_RS11165
uniprot id: A0A8H9YV77
names: Similarity
messages: Belongs to the thioesterase PaaI family.

2745518:HU722 RS19820
gene id: 2745518:HU722_RS19820
uniprot id: A0A8H9Z1L2
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS20565
gene id: 2745518:HU722_RS20565
uniprot id: A0A8I0CUH3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS23360
gene id: 2745518:HU722_RS23360
uniprot id: A0A8I0CU59
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

2745518:HU722 RS00360
gene id: 2745518:HU722_RS00360
uniprot id: A0A8I0D099
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Cytoplasm

2745518:HU722 RS11615
gene id: 2745518:HU722_RS11615
uniprot id: A0A8H9Z3U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS06505
gene id: 2745518:HU722_RS06505
uniprot id: A0A8I0CX95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

2745518:HU722 RS07425
gene id: 2745518:HU722_RS07425
uniprot id: A0A8H9Z3M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

2745518:HU722 RS08550
gene id: 2745518:HU722_RS08550
uniprot id: A0A8I0CZY5
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS18235
gene id: 2745518:HU722_RS18235
uniprot id: A0A8H9YRH3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

2745518:HU722 RS05460
gene id: 2745518:HU722_RS05460
uniprot id: A0A8I0CYA9
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

2745518:HU722 RS21900
gene id: 2745518:HU722_RS21900
uniprot id: A0A8I0CTT6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS11960
gene id: 2745518:HU722_RS11960
uniprot id: A0A8I0D159
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS22710
gene id: 2745518:HU722_RS22710
uniprot id: A0A8H9YM00
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

2745518:HU722 RS03570
gene id: 2745518:HU722_RS03570
uniprot id: A0A8I0CVR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

2745518:HU722 RS22760
gene id: 2745518:HU722_RS22760
uniprot id: A0A8I0CUW9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

2745518:HU722 RS01165
gene id: 2745518:HU722_RS01165
uniprot id: A0A8H9YVH2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

2745518:HU722 RS03035
gene id: 2745518:HU722_RS03035
uniprot id: A0A8I0CVJ8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

2745518:HU722 RS05715
gene id: 2745518:HU722_RS05715
uniprot id: A0A8H9YTY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

2745518:HU722 RS00125
gene id: 2745518:HU722_RS00125
uniprot id: A0A8I0CZJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

2745518:HU722 RS22380
gene id: 2745518:HU722_RS22380
uniprot id: A0A8H9YJ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

2745518:HU722 RS26060
gene id: 2745518:HU722_RS26060
uniprot id: A0A8I0CWR3
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

2745518:HU722 RS11565
gene id: 2745518:HU722_RS11565
uniprot id: A0A8I0D2S4
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

2745518:HU722 RS02565
gene id: 2745518:HU722_RS02565
uniprot id: A0A8H9YXQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

2745518:HU722 RS08895
gene id: 2745518:HU722_RS08895
uniprot id: A0A8H9YT13
names: Similarity
messages: Belongs to the MlaA family.

2745518:HU722 RS13395
gene id: 2745518:HU722_RS13395
uniprot id: A0A8H9YYP1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745518:HU722 RS05995
gene id: 2745518:HU722_RS05995
uniprot id: A0A8I0CY95
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

2745518:HU722 RS03840
gene id: 2745518:HU722_RS03840
uniprot id: A0A8H9YNM7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

2745518:HU722 RS06460
gene id: 2745518:HU722_RS06460
uniprot id: A0A8H9YT24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

2745518:HU722 RS09610
gene id: 2745518:HU722_RS09610
uniprot id: A0A8I0CX40
names: Similarity
messages: Belongs to the glutathione peroxidase family.

2745518:HU722 RS27810
gene id: 2745518:HU722_RS27810
uniprot id: A0A8H9YSG5
names: Similarity
messages: Belongs to the GSP E family.

2745518:HU722 RS05585
gene id: 2745518:HU722_RS05585
uniprot id: A0A8F4X0U5
names: Similarity
messages: Belongs to the peptidase U62 family.

2745518:HU722 RS03155
gene id: 2745518:HU722_RS03155
uniprot id: A0A8H9YNW1
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

2745518:HU722 RS01125
gene id: 2745518:HU722_RS01125
uniprot id: A0A8H9YUH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

2745518:HU722 RS18555
gene id: 2745518:HU722_RS18555
uniprot id: A0A8I0D1X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS18530
gene id: 2745518:HU722_RS18530
uniprot id: A0A8H9Z4C5
names: Similarity
messages: Belongs to the peptidase S11 family.

2745518:HU722 RS07450
gene id: 2745518:HU722_RS07450
uniprot id: A0A8I0D205
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

2745518:HU722 RS16970
gene id: 2745518:HU722_RS16970
uniprot id: A0A8H9Z354
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

2745518:HU722 RS06050
gene id: 2745518:HU722_RS06050
uniprot id: A0A8H9YV16
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS19545
gene id: 2745518:HU722_RS19545
uniprot id: A0A8H9Z4S2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2745518:HU722 RS07970
gene id: 2745518:HU722_RS07970
uniprot id: A0A8I0D2G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS00660
gene id: 2745518:HU722_RS00660
uniprot id: A0A8H9YVQ8
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

2745518:HU722 RS00655
gene id: 2745518:HU722_RS00655
uniprot id: A0A8H9YWE9
names: Similarity
messages: Belongs to the gamma-class carbonic anhydrase family.

2745518:HU722 RS10515
gene id: 2745518:HU722_RS10515
uniprot id: A0A8H9YTY5
names: Similarity
messages: Belongs to the Gfa family.

2745518:HU722 RS19340
gene id: 2745518:HU722_RS19340
uniprot id: A0A8H9Z0A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

2745518:HU722 RS03130
gene id: 2745518:HU722_RS03130
uniprot id: A0A8H9YPU7
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

2745518:HU722 RS24830
gene id: 2745518:HU722_RS24830
uniprot id: A0A8I0D259
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

2745518:HU722 RS03585
gene id: 2745518:HU722_RS03585
uniprot id: A0A8I0CV19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

2745518:HU722 RS00185
gene id: 2745518:HU722_RS00185
uniprot id: A0A8H9YZV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

2745518:HU722 RS23685
gene id: 2745518:HU722_RS23685
uniprot id: A0A8H9YKE2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

2745518:HU722 RS23140
gene id: 2745518:HU722_RS23140
uniprot id: A0A8I0CUN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS19185
gene id: 2745518:HU722_RS19185
uniprot id: A0A8H9Z085
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2745518:HU722 RS01700
gene id: 2745518:HU722_RS01700
uniprot id: A0A8I0D1R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS02530
gene id: 2745518:HU722_RS02530
uniprot id: A0A8I0CZD7
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

2745518:HU722 RS22865
gene id: 2745518:HU722_RS22865
uniprot id: A0A8H9YM22
names: Similarity
messages: Belongs to the CTP synthase family.

2745518:HU722 RS07420
gene id: 2745518:HU722_RS07420
uniprot id: A0A8H9Z2X5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS13735
gene id: 2745518:HU722_RS13735
uniprot id: A0A8H9Z332
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2745518:HU722 RS04030
gene id: 2745518:HU722_RS04030
uniprot id: A0A8I0CUZ3
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

2745518:HU722 RS05595
gene id: 2745518:HU722_RS05595
uniprot id: A0A8I0CX38
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

2745518:HU722 RS03715
gene id: 2745518:HU722_RS03715
uniprot id: A0A8I0CVQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

2745518:HU722 RS28425
gene id: 2745518:HU722_RS28425
uniprot id: A0A8I0D1M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

2745518:HU722 RS26035
gene id: 2745518:HU722_RS26035
uniprot id: A0A8H9YRL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

2745518:HU722 RS25725
gene id: 2745518:HU722_RS25725
uniprot id: A0A8H9YRL0
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS24200
gene id: 2745518:HU722_RS24200
uniprot id: A0A8H9Z072
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

2745518:HU722 RS16325
gene id: 2745518:HU722_RS16325
uniprot id: A0A8H9YY69
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS27095
gene id: 2745518:HU722_RS27095
uniprot id: A0A8I0CXF5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

2745518:HU722 RS04040
gene id: 2745518:HU722_RS04040
uniprot id: A0A8H9YPG6
names: Function
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.
messages: Protects the bacterial cell from host peptidases.

2745518:HU722 RS23850
gene id: 2745518:HU722_RS23850
uniprot id: A0A8H9YLE2
names: Similarity
messages: Belongs to the RecJ family.

2745518:HU722 RS07115
gene id: 2745518:HU722_RS07115
uniprot id: A0A8H9YXF3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.
messages: Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs).

2745518:HU722 RS15755
gene id: 2745518:HU722_RS15755
uniprot id: A0A8H9YWF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS04185
gene id: 2745518:HU722_RS04185
uniprot id: A0A8I0CUA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

2745518:HU722 RS24630
gene id: 2745518:HU722_RS24630
uniprot id: A0A8H9Z0Y6
names: Similarity
messages: Belongs to the YjdM family.

2745518:HU722 RS21020
gene id: 2745518:HU722_RS21020
uniprot id: A0A8H9YI90
names: Subcellular Location Annotation
messages: Cell inner membrane

2745518:HU722 RS04525
gene id: 2745518:HU722_RS04525
uniprot id: A0A8H9YNS7
names: Similarity
messages: Belongs to the IMPACT family.

2745518:HU722 RS05610
gene id: 2745518:HU722_RS05610
uniprot id: A0A8I0CY71
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS03650
gene id: 2745518:HU722_RS03650
uniprot id: A0A8I0CUZ5
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

2745518:HU722 RS27230
gene id: 2745518:HU722_RS27230
uniprot id: A0A8H9YR59
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

2745518:HU722 RS26055
gene id: 2745518:HU722_RS26055
uniprot id: A0A8I0CWK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

2745518:HU722 RS27240
gene id: 2745518:HU722_RS27240
uniprot id: A0A8I0CXJ3
names: Similarity
messages: Belongs to the GcvT family.

2745518:HU722 RS09435
gene id: 2745518:HU722_RS09435
uniprot id: A0A8H9YRM4
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS00200
gene id: 2745518:HU722_RS00200
uniprot id: A0A8I0CZK0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS03720
gene id: 2745518:HU722_RS03720
uniprot id: A0A8I0CVF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

2745518:HU722 RS06115
gene id: 2745518:HU722_RS06115
uniprot id: A0A8H9YV59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AlgF family.
messages: Periplasm

2745518:HU722 RS24185
gene id: 2745518:HU722_RS24185
uniprot id: A0A8H9Z117
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

2745518:HU722 RS26485
gene id: 2745518:HU722_RS26485
uniprot id: A0A8H9YRR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

2745518:HU722 RS06415
gene id: 2745518:HU722_RS06415
uniprot id: A0A8H9YV99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS15220
gene id: 2745518:HU722_RS15220
uniprot id: A0A8H9YW87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 83 family.
messages: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

2745518:HU722 RS07605
gene id: 2745518:HU722_RS07605
uniprot id: A0A8I0D2L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

2745518:HU722 RS28665
gene id: 2745518:HU722_RS28665
uniprot id: A0A8I0D0K9
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

2745518:HU722 RS02000
gene id: 2745518:HU722_RS02000
uniprot id: A0A8H9YZP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

2745518:HU722 RS06975
gene id: 2745518:HU722_RS06975
uniprot id: A0A8H9YXM1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2745518:HU722 RS00620
gene id: 2745518:HU722_RS00620
uniprot id: A0A8I0CYN5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

2745518:HU722 RS17720
gene id: 2745518:HU722_RS17720
uniprot id: A0A8H9YR33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

2745518:HU722 RS28055
gene id: 2745518:HU722_RS28055
uniprot id: A0A8I0D1Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS12575
gene id: 2745518:HU722_RS12575
uniprot id: A0A8H9Z273
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

2745518:HU722 RS04845
gene id: 2745518:HU722_RS04845
uniprot id: A0A8I0D1T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

2745518:HU722 RS23375
gene id: 2745518:HU722_RS23375
uniprot id: A0A8H9YKB2
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS24430
gene id: 2745518:HU722_RS24430
uniprot id: A0A8H9Z041
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

2745518:HU722 RS06120
gene id: 2745518:HU722_RS06120
uniprot id: A0A8H9YU05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AlgJ family.
messages: Cell inner membrane
messages: Periplasm

2745518:HU722 RS03400
gene id: 2745518:HU722_RS03400
uniprot id: A0A8H9YME3
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

2745518:HU722 RS25585
gene id: 2745518:HU722_RS25585
uniprot id: A0A8H9YRG3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS23105
gene id: 2745518:HU722_RS23105
uniprot id: A0A8H9YM99
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

2745518:HU722 RS16450
gene id: 2745518:HU722_RS16450
uniprot id: A0A8I0CZJ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS05900
gene id: 2745518:HU722_RS05900
uniprot id: A0A8H9YV01
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

2745518:HU722 RS02785
gene id: 2745518:HU722_RS02785
uniprot id: A0A8H9YN93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. OpgH subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
messages: Membrane

2745518:HU722 RS14080
gene id: 2745518:HU722_RS14080
uniprot id: A0A8H9YY46
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.

2745518:HU722 RS14635
gene id: 2745518:HU722_RS14635
uniprot id: A0A8H9Z222
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

2745518:HU722 RS23490
gene id: 2745518:HU722_RS23490
uniprot id: A0A8H9YN20
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS19705
gene id: 2745518:HU722_RS19705
uniprot id: A0A8H9Z2D9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS02680
gene id: 2745518:HU722_RS02680
uniprot id: A0A8H9YPZ6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS08370
gene id: 2745518:HU722_RS08370
uniprot id: A0A8H9YYQ1
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

2745518:HU722 RS23120
gene id: 2745518:HU722_RS23120
uniprot id: A0A8H9YN16
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

2745518:HU722 RS23905
gene id: 2745518:HU722_RS23905
uniprot id: A0A8I0D212
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2745518:HU722 RS18960
gene id: 2745518:HU722_RS18960
uniprot id: A0A8H9Z0F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS27105
gene id: 2745518:HU722_RS27105
uniprot id: A0A8I0CWX6
names: Similarity
messages: Belongs to the ModE family.

2745518:HU722 RS26645
gene id: 2745518:HU722_RS26645
uniprot id: A0A8I0CW76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2745518:HU722 RS17990
gene id: 2745518:HU722_RS17990
uniprot id: A0A8H9YQ15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

2745518:HU722 RS15395
gene id: 2745518:HU722_RS15395
uniprot id: A0A8I0CZE9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS20735
gene id: 2745518:HU722_RS20735
uniprot id: A0A8H9YIN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

2745518:HU722 RS26840
gene id: 2745518:HU722_RS26840
uniprot id: A0A8H9YRX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS18290
gene id: 2745518:HU722_RS18290
uniprot id: A0A8H9YQ58
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745518:HU722 RS02770
gene id: 2745518:HU722_RS02770
uniprot id: A0A8H9YP78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

2745518:HU722 RS20165
gene id: 2745518:HU722_RS20165
uniprot id: A0A8I0D0X2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2745518:HU722 RS00330
gene id: 2745518:HU722_RS00330
uniprot id: A0A8H9YZB7
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

2745518:HU722 RS02780
gene id: 2745518:HU722_RS02780
uniprot id: A0A8F4WYH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
messages: Periplasm

2745518:HU722 RS00760
gene id: 2745518:HU722_RS00760
uniprot id: A0A8I0CZ84
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

2745518:HU722 RS04850
gene id: 2745518:HU722_RS04850
uniprot id: A0A8I0D1S9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

2745518:HU722 RS19415
gene id: 2745518:HU722_RS19415
uniprot id: A0A8H9Z2K2
names: Similarity
messages: Belongs to the TrpF family.

2745518:HU722 RS00110
gene id: 2745518:HU722_RS00110
uniprot id: A0A8H9YZU2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS11325
gene id: 2745518:HU722_RS11325
uniprot id: A0A8H9YUP3
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

2745518:HU722 RS24100
gene id: 2745518:HU722_RS24100
uniprot id: A0A8F4WWE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2745518:HU722 RS01830
gene id: 2745518:HU722_RS01830
uniprot id: A0A8H9Z0X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

2745518:HU722 RS01015
gene id: 2745518:HU722_RS01015
uniprot id: A0A8H9YVJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

2745518:HU722 RS21435
gene id: 2745518:HU722_RS21435
uniprot id: A0A8H9YME2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS01065
gene id: 2745518:HU722_RS01065
uniprot id: A0A8I0CZ20
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2745518:HU722 RS07060
gene id: 2745518:HU722_RS07060
uniprot id: A0A8H9YW16
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

2745518:HU722 RS11510
gene id: 2745518:HU722_RS11510
uniprot id: A0A8I0CYK6
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

2745518:HU722 RS11695
gene id: 2745518:HU722_RS11695
uniprot id: A0A8I0D1I1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS04970
gene id: 2745518:HU722_RS04970
uniprot id: A0A8H9Z1E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

2745518:HU722 RS01495
gene id: 2745518:HU722_RS01495
uniprot id: A0A8H9Z3Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

2745518:HU722 RS02285
gene id: 2745518:HU722_RS02285
uniprot id: A0A8I0D039
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

2745518:HU722 RS19905
gene id: 2745518:HU722_RS19905
uniprot id: A0A8H9YZ49
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

2745518:HU722 RS04900
gene id: 2745518:HU722_RS04900
uniprot id: A0A8H9Z121
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PagL family.
messages: Cell outer membrane
messages: Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety.
messages: Homodimer.

2745518:HU722 RS27160
gene id: 2745518:HU722_RS27160
uniprot id: A0A8H9YR60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS25610
gene id: 2745518:HU722_RS25610
uniprot id: A0A8I0CWN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS05255
gene id: 2745518:HU722_RS05255
uniprot id: A0A8H9Z3C4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS02540
gene id: 2745518:HU722_RS02540
uniprot id: A0A8H9YYD5
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS07465
gene id: 2745518:HU722_RS07465
uniprot id: A0A8H9Z1G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

2745518:HU722 RS07485
gene id: 2745518:HU722_RS07485
uniprot id: A0A8H9Z287
names: Subcellular Location Annotation
messages: Cytoplasm

2745518:HU722 RS23630
gene id: 2745518:HU722_RS23630
uniprot id: A0A8H9YMT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

2745518:HU722 RS09765
gene id: 2745518:HU722_RS09765
uniprot id: A0A8I0CWH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

2745518:HU722 RS26820
gene id: 2745518:HU722_RS26820
uniprot id: A0A8H9YTI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

2745518:HU722 RS22220
gene id: 2745518:HU722_RS22220
uniprot id: A0A8I0CUT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

2745518:HU722 RS06515
gene id: 2745518:HU722_RS06515
uniprot id: A0A8I0CXW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

2745518:HU722 RS24890
gene id: 2745518:HU722_RS24890
uniprot id: A0A8H9YR84
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

2745518:HU722 RS24495
gene id: 2745518:HU722_RS24495
uniprot id: A0A8H9Z205
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2745518:HU722 RS28255
gene id: 2745518:HU722_RS28255
uniprot id: A0A8H9Z0R8
names: Function
names: Similarity
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.

2745518:HU722 RS12150
gene id: 2745518:HU722_RS12150
uniprot id: A0A8H9Z0Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS09095
gene id: 2745518:HU722_RS09095
uniprot id: A0A8I0CWL6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS02965
gene id: 2745518:HU722_RS02965
uniprot id: A0A8I0CV40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS14085
gene id: 2745518:HU722_RS14085
uniprot id: A0A8H9YY14
names: Similarity
messages: Belongs to the EfeM/EfeO family.

2745518:HU722 RS21555
gene id: 2745518:HU722_RS21555
uniprot id: A0A8H9YKG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

2745518:HU722 RS02275
gene id: 2745518:HU722_RS02275
uniprot id: A0A8I0D0N7
names: Similarity
messages: Belongs to the HSP15 family.

2745518:HU722 RS23460
gene id: 2745518:HU722_RS23460
uniprot id: A0A8H9YK55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS22455
gene id: 2745518:HU722_RS22455
uniprot id: A0A8H9YJ78
names: Similarity
messages: Belongs to the fabD family.

2745518:HU722 RS17060
gene id: 2745518:HU722_RS17060
uniprot id: A0A8H9YPQ9
names: Similarity
messages: Belongs to the peptidase C56 family.

2745518:HU722 RS19245
gene id: 2745518:HU722_RS19245
uniprot id: A0A8H9Z0P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

2745518:HU722 RS15580
gene id: 2745518:HU722_RS15580
uniprot id: A0A8H9YX33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

2745518:HU722 RS14385
gene id: 2745518:HU722_RS14385
uniprot id: A0A8I0D0Y2
names: Similarity
messages: Belongs to the peptidase S58 family.

2745518:HU722 RS17470
gene id: 2745518:HU722_RS17470
uniprot id: A0A8H9YRL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

2745518:HU722 RS21265
gene id: 2745518:HU722_RS21265
uniprot id: A0A8H9YL89
names: Similarity
messages: Belongs to the CvfB family.

2745518:HU722 RS03640
gene id: 2745518:HU722_RS03640
uniprot id: A0A8I0CVQ7
names: Function
names: Subcellular Location Annotation
messages: Periplasm
messages: Transfers electrons from cytochrome c551 to cytochrome oxidase.

2745518:HU722 RS24800
gene id: 2745518:HU722_RS24800
uniprot id: A0A8H9Z2R1
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS12615
gene id: 2745518:HU722_RS12615
uniprot id: A0A8I0D1X7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS23330
gene id: 2745518:HU722_RS23330
uniprot id: A0A8H9YMD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

2745518:HU722 RS00530
gene id: 2745518:HU722_RS00530
uniprot id: A0A8H9YUP5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2745518:HU722 RS09945
gene id: 2745518:HU722_RS09945
uniprot id: A0A8H9YSN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS03770
gene id: 2745518:HU722_RS03770
uniprot id: A0A8H9YMX8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

2745518:HU722 RS22935
gene id: 2745518:HU722_RS22935
uniprot id: A0A8H9YLB4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS23280
gene id: 2745518:HU722_RS23280
uniprot id: A0A8I0CU90
names: Similarity
messages: Belongs to the YciI family.

2745518:HU722 RS09750
gene id: 2745518:HU722_RS09750
uniprot id: A0A8I0CXK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

2745518:HU722 RS19460
gene id: 2745518:HU722_RS19460
uniprot id: A0A8I0D1V7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS04700
gene id: 2745518:HU722_RS04700
uniprot id: A0A8I0D161
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

2745518:HU722 RS10040
gene id: 2745518:HU722_RS10040
uniprot id: A0A8H9YRC4
names: Subcellular Location Annotation
messages: Cell inner membrane

2745518:HU722 RS13745
gene id: 2745518:HU722_RS13745
uniprot id: A0A8H9Z312
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS14115
gene id: 2745518:HU722_RS14115
uniprot id: A0A8H9Z031
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

2745518:HU722 RS08415
gene id: 2745518:HU722_RS08415
uniprot id: A0A8H9YX80
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

2745518:HU722 RS05745
gene id: 2745518:HU722_RS05745
uniprot id: A0A8I0CX46
names: Similarity
messages: Belongs to the MQO family.

2745518:HU722 RS12205
gene id: 2745518:HU722_RS12205
uniprot id: A0A8H9YZY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

2745518:HU722 RS28105
gene id: 2745518:HU722_RS28105
uniprot id: A0A8H9Z3Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

2745518:HU722 RS18995
gene id: 2745518:HU722_RS18995
uniprot id: A0A8I0D157
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS24640
gene id: 2745518:HU722_RS24640
uniprot id: A0A8H9Z274
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2745518:HU722 RS02820
gene id: 2745518:HU722_RS02820
uniprot id: A0A8I0CV70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

2745518:HU722 RS01020
gene id: 2745518:HU722_RS01020
uniprot id: A0A8H9YWN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

2745518:HU722 RS27865
gene id: 2745518:HU722_RS27865
uniprot id: A0A8I0CW89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

2745518:HU722 RS05555
gene id: 2745518:HU722_RS05555
uniprot id: A0A8H9YSY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

2745518:HU722 RS09955
gene id: 2745518:HU722_RS09955
uniprot id: A0A8H9YRP6
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

2745518:HU722 RS16920
gene id: 2745518:HU722_RS16920
uniprot id: A0A8H9Z2J4
names: Similarity
messages: Belongs to the UPF0053 family.

2745518:HU722 RS17695
gene id: 2745518:HU722_RS17695
uniprot id: A0A8H9YQK9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

2745518:HU722 RS00435
gene id: 2745518:HU722_RS00435
uniprot id: A0A8I0D0A2
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

2745518:HU722 RS24885
gene id: 2745518:HU722_RS24885
uniprot id: A0A8H9YQ57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

2745518:HU722 RS27590
gene id: 2745518:HU722_RS27590
uniprot id: A0A8H9YSS2
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

2745518:HU722 RS22335
gene id: 2745518:HU722_RS22335
uniprot id: A0A8H9YMN7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS08425
gene id: 2745518:HU722_RS08425
uniprot id: A0A8H9YXA3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745518:HU722 RS13030
gene id: 2745518:HU722_RS13030
uniprot id: A0A8H9Z201
names: Similarity
messages: Belongs to the RNase T2 family.

2745518:HU722 RS19825
gene id: 2745518:HU722_RS19825
uniprot id: A0A8H9Z1M1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745518:HU722 RS05970
gene id: 2745518:HU722_RS05970
uniprot id: A0A8H9YTY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

2745518:HU722 RS20925
gene id: 2745518:HU722_RS20925
uniprot id: A0A8I0CTG9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

2745518:HU722 RS20115
gene id: 2745518:HU722_RS20115
uniprot id: A0A8F5AB35
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

2745518:HU722 RS02260
gene id: 2745518:HU722_RS02260
uniprot id: A0A8H9YXJ6
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

2745518:HU722 RS05375
gene id: 2745518:HU722_RS05375
uniprot id: A0A8I0D2N6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

2745518:HU722 RS06125
gene id: 2745518:HU722_RS06125
uniprot id: A0A8H9YV23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS25940
gene id: 2745518:HU722_RS25940
uniprot id: A0A8H9YR45
names: Similarity
messages: Belongs to the PhoH family.

2745518:HU722 RS11940
gene id: 2745518:HU722_RS11940
uniprot id: A0A8H9Z1V1
names: Similarity
messages: Belongs to the aldose epimerase family.

2745518:HU722 RS09545
gene id: 2745518:HU722_RS09545
uniprot id: A0A8H9YTR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS22435
gene id: 2745518:HU722_RS22435
uniprot id: A0A8I0CTW9
names: Subunit
messages: Homodimer.

2745518:HU722 RS12035
gene id: 2745518:HU722_RS12035
uniprot id: A0A8I0D162
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS22665
gene id: 2745518:HU722_RS22665
uniprot id: A0A8I0CSY2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

2745518:HU722 RS25090
gene id: 2745518:HU722_RS25090
uniprot id: A0A8H9YPH6
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

2745518:HU722 RS03545
gene id: 2745518:HU722_RS03545
uniprot id: A0A8H9YMQ9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745518:HU722 RS07480
gene id: 2745518:HU722_RS07480
uniprot id: A0A8H9Z1W2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

2745518:HU722 RS17925
gene id: 2745518:HU722_RS17925
uniprot id: A0A8H9YQD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS21695
gene id: 2745518:HU722_RS21695
uniprot id: A0A8H9YIQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

2745518:HU722 RS20330
gene id: 2745518:HU722_RS20330
uniprot id: A0A8H9YYB5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745518:HU722 RS27875
gene id: 2745518:HU722_RS27875
uniprot id: A0A8H9YRY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

2745518:HU722 RS15225
gene id: 2745518:HU722_RS15225
uniprot id: A0A8H9YX84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnE family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Membrane
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

2745518:HU722 RS02595
gene id: 2745518:HU722_RS02595
uniprot id: A0A8I0D019
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

2745518:HU722 RS05315
gene id: 2745518:HU722_RS05315
uniprot id: A0A8I0D234
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

2745518:HU722 RS19975
gene id: 2745518:HU722_RS19975
uniprot id: A0A8H9Z096
names: Similarity
messages: Belongs to the glutamine synthetase family.

2745518:HU722 RS08135
gene id: 2745518:HU722_RS08135
uniprot id: A0A8H9YYM0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

2745518:HU722 RS01355
gene id: 2745518:HU722_RS01355
uniprot id: A0A8H9YUD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS20575
gene id: 2745518:HU722_RS20575
uniprot id: A0A8H9YHQ9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS24090
gene id: 2745518:HU722_RS24090
uniprot id: A0A8H9Z133
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS10245
gene id: 2745518:HU722_RS10245
uniprot id: A0A8H9Z387
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

2745518:HU722 RS02910
gene id: 2745518:HU722_RS02910
uniprot id: A0A8H9YNN9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

2745518:HU722 RS02210
gene id: 2745518:HU722_RS02210
uniprot id: A0A8I0D043
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

2745518:HU722 RS13625
gene id: 2745518:HU722_RS13625
uniprot id: A0A8H9YYS1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS02930
gene id: 2745518:HU722_RS02930
uniprot id: A0A8H9YNZ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2745518:HU722 RS22440
gene id: 2745518:HU722_RS22440
uniprot id: A0A8I0CUJ5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

2745518:HU722 RS11215
gene id: 2745518:HU722_RS11215
uniprot id: A0A8I0CY62
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

2745518:HU722 RS19605
gene id: 2745518:HU722_RS19605
uniprot id: A0A8H9Z1Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

2745518:HU722 RS24955
gene id: 2745518:HU722_RS24955
uniprot id: A0A8H9YRB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

2745518:HU722 RS13910
gene id: 2745518:HU722_RS13910
uniprot id: A0A8I0D096
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS28100
gene id: 2745518:HU722_RS28100
uniprot id: A0A8H9Z369
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

2745518:HU722 RS00650
gene id: 2745518:HU722_RS00650
uniprot id: A0A8H9YW69
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

2745518:HU722 RS22345
gene id: 2745518:HU722_RS22345
uniprot id: A0A8H9YMS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm

2745518:HU722 RS27650
gene id: 2745518:HU722_RS27650
uniprot id: A0A8H9YS13
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

2745518:HU722 RS25900
gene id: 2745518:HU722_RS25900
uniprot id: A0A8I0CW21
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745518:HU722 RS27425
gene id: 2745518:HU722_RS27425
uniprot id: A0A8H9YTA5
names: Similarity
messages: Belongs to the peptidase U62 family.

2745518:HU722 RS27880
gene id: 2745518:HU722_RS27880
uniprot id: A0A8H9YT44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

2745518:HU722 RS21625
gene id: 2745518:HU722_RS21625
uniprot id: A0A8H9YIM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

2745518:HU722 RS01375
gene id: 2745518:HU722_RS01375
uniprot id: A0A8I0CYI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS08760
gene id: 2745518:HU722_RS08760
uniprot id: A0A8H9YYB4
names: Function
names: Similarity
names: Subunit
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).
messages: In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.

2745518:HU722 RS03950
gene id: 2745518:HU722_RS03950
uniprot id: A0A8I0CUX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS07545
gene id: 2745518:HU722_RS07545
uniprot id: A0A8H9Z1H2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

2745518:HU722 RS26470
gene id: 2745518:HU722_RS26470
uniprot id: A0A8H9YR91
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.

2745518:HU722 RS26535
gene id: 2745518:HU722_RS26535
uniprot id: A0A8H9YQZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2745518:HU722 RS26640
gene id: 2745518:HU722_RS26640
uniprot id: A0A8I0CVL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2745518:HU722 RS26395
gene id: 2745518:HU722_RS26395
uniprot id: A0A8H9YR79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

2745518:HU722 RS03370
gene id: 2745518:HU722_RS03370
uniprot id: A0A8H9YNZ1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

2745518:HU722 RS04975
gene id: 2745518:HU722_RS04975
uniprot id: A0A8H9Z111
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS01425
gene id: 2745518:HU722_RS01425
uniprot id: A0A8H9YUD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

2745518:HU722 RS20775
gene id: 2745518:HU722_RS20775
uniprot id: A0A8I0CRT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

2745518:HU722 RS15215
gene id: 2745518:HU722_RS15215
uniprot id: A0A8H9YXB9
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
messages: Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

2745518:HU722 RS16850
gene id: 2745518:HU722_RS16850
uniprot id: A0A8H9Z256
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2745518:HU722 RS21545
gene id: 2745518:HU722_RS21545
uniprot id: A0A8H9YIK7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

2745518:HU722 RS01460
gene id: 2745518:HU722_RS01460
uniprot id: A0A8H9YWD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

2745518:HU722 RS11120
gene id: 2745518:HU722_RS11120
uniprot id: A0A8F5AEE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SelU family.
messages: Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
messages: Monomer.

2745518:HU722 RS00910
gene id: 2745518:HU722_RS00910
uniprot id: A0A8I0CZ75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

2745518:HU722 RS15440
gene id: 2745518:HU722_RS15440
uniprot id: A0A8H9YXE8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

2745518:HU722 RS08765
gene id: 2745518:HU722_RS08765
uniprot id: A0A8H9YZD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

2745518:HU722 RS19895
gene id: 2745518:HU722_RS19895
uniprot id: A0A8H9YZP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

2745518:HU722 RS26280
gene id: 2745518:HU722_RS26280
uniprot id: A0A8I0CWM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

2745518:HU722 RS19405
gene id: 2745518:HU722_RS19405
uniprot id: A0A8I0D348
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

2745518:HU722 RS03605
gene id: 2745518:HU722_RS03605
uniprot id: A0A8H9YPJ8
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

2745518:HU722 RS20780
gene id: 2745518:HU722_RS20780
uniprot id: A0A8I0CTF5
names: Subcellular Location Annotation
messages: Cytoplasm

2745518:HU722 RS21220
gene id: 2745518:HU722_RS21220
uniprot id: A0A8I0CS66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

2745518:HU722 RS18225
gene id: 2745518:HU722_RS18225
uniprot id: A0A8H9YQI1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

2745518:HU722 RS04170
gene id: 2745518:HU722_RS04170
uniprot id: A0A8I0CVC1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2745518:HU722 RS03860
gene id: 2745518:HU722_RS03860
uniprot id: A0A8H9YM87
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS00040
gene id: 2745518:HU722_RS00040
uniprot id: A0A8H9YYP8
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

2745518:HU722 RS15185
gene id: 2745518:HU722_RS15185
uniprot id: A0A8H9YV60
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745518:HU722 RS15940
gene id: 2745518:HU722_RS15940
uniprot id: A0A8H9YXQ8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

2745518:HU722 RS25945
gene id: 2745518:HU722_RS25945
uniprot id: A0A8H9YR36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

2745518:HU722 RS05415
gene id: 2745518:HU722_RS05415
uniprot id: A0A8H9YUE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

2745518:HU722 RS17750
gene id: 2745518:HU722_RS17750
uniprot id: A0A8I0CWC5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

2745518:HU722 RS23450
gene id: 2745518:HU722_RS23450
uniprot id: A0A8I0CV10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

2745518:HU722 RS07780
gene id: 2745518:HU722_RS07780
uniprot id: A0A8H9Z2M3
names: Similarity
messages: Belongs to the UPF0276 family.

2745518:HU722 RS25175
gene id: 2745518:HU722_RS25175
uniprot id: A0A8H9YQF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2745518:HU722 RS01405
gene id: 2745518:HU722_RS01405
uniprot id: A0A8H9YW47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

2745518:HU722 RS08490
gene id: 2745518:HU722_RS08490
uniprot id: A0A8I0D0J9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS16705
gene id: 2745518:HU722_RS16705
uniprot id: A0A8H9Z1U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS09550
gene id: 2745518:HU722_RS09550
uniprot id: A0A8H9YSN0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS03360
gene id: 2745518:HU722_RS03360
uniprot id: A0A8H9YNH9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS07460
gene id: 2745518:HU722_RS07460
uniprot id: A0A8I0D2K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

2745518:HU722 RS24035
gene id: 2745518:HU722_RS24035
uniprot id: A0A8H9Z0N8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

2745518:HU722 RS23885
gene id: 2745518:HU722_RS23885
uniprot id: A0A8H9YNB7
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

2745518:HU722 RS06925
gene id: 2745518:HU722_RS06925
uniprot id: A0A8H9YVX7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

2745518:HU722 RS20000
gene id: 2745518:HU722_RS20000
uniprot id: A0A8I0D0G0
names: Similarity
messages: Belongs to the PrpF family.

2745518:HU722 RS17365
gene id: 2745518:HU722_RS17365
uniprot id: A0A8H9YPT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

2745518:HU722 RS00130
gene id: 2745518:HU722_RS00130
uniprot id: A0A8I0D070
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

2745518:HU722 RS23045
gene id: 2745518:HU722_RS23045
uniprot id: A0A8H9YN06
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

2745518:HU722 RS12745
gene id: 2745518:HU722_RS12745
uniprot id: A0A8H9Z0W2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2745518:HU722 RS06350
gene id: 2745518:HU722_RS06350
uniprot id: A0A8H9YV48
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the homogentisate dioxygenase family.
messages: Hexamer; dimer of trimers.
messages: Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS06880
gene id: 2745518:HU722_RS06880
uniprot id: A0A8H9YXY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

2745518:HU722 RS20140
gene id: 2745518:HU722_RS20140
uniprot id: A0A8H9YZ80
names: Similarity
messages: Belongs to the asparagine synthetase family.

2745518:HU722 RS03260
gene id: 2745518:HU722_RS03260
uniprot id: A0A8I0CVI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS15555
gene id: 2745518:HU722_RS15555
uniprot id: A0A8F4WSC8
names: Cofactor
messages: Binds 1 zinc ion per subunit.

2745518:HU722 RS22655
gene id: 2745518:HU722_RS22655
uniprot id: A0A8H9YLI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

2745518:HU722 RS11550
gene id: 2745518:HU722_RS11550
uniprot id: A0A8I0D268
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS07765
gene id: 2745518:HU722_RS07765
uniprot id: A0A8H9Z1J5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS13105
gene id: 2745518:HU722_RS13105
uniprot id: A0A8H9YYF8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

2745518:HU722 RS11705
gene id: 2745518:HU722_RS11705
uniprot id: A0A8I0D287
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

2745518:HU722 RS03460
gene id: 2745518:HU722_RS03460
uniprot id: A0A8H9YN07
names: Similarity
messages: Belongs to the MotB family.

2745518:HU722 RS21675
gene id: 2745518:HU722_RS21675
uniprot id: A0A8I0CTQ8
names: Similarity
messages: Belongs to the peptidase S13 family.

2745518:HU722 RS13360
gene id: 2745518:HU722_RS13360
uniprot id: A0A8H9YZF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS26045
gene id: 2745518:HU722_RS26045
uniprot id: A0A8I0CW39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

2745518:HU722 RS03965
gene id: 2745518:HU722_RS03965
uniprot id: A0A8H9YPI4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

2745518:HU722 RS25125
gene id: 2745518:HU722_RS25125
uniprot id: A0A8H9YRA7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

2745518:HU722 RS00135
gene id: 2745518:HU722_RS00135
uniprot id: A0A8I0D086
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

2745518:HU722 RS24710
gene id: 2745518:HU722_RS24710
uniprot id: A0A8H9Z1E0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

2745518:HU722 RS04200
gene id: 2745518:HU722_RS04200
uniprot id: A0A8H9YPA0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745518:HU722 RS04985
gene id: 2745518:HU722_RS04985
uniprot id: A0A8H9Z103
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

2745518:HU722 RS03655
gene id: 2745518:HU722_RS03655
uniprot id: A0A8I0CV14
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS06495
gene id: 2745518:HU722_RS06495
uniprot id: A0A8H9YU50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

2745518:HU722 RS17685
gene id: 2745518:HU722_RS17685
uniprot id: A0A8H9YQ05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

2745518:HU722 RS27660
gene id: 2745518:HU722_RS27660
uniprot id: A0A8H9YSI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

2745518:HU722 RS06395
gene id: 2745518:HU722_RS06395
uniprot id: A0A8H9YTJ7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS26615
gene id: 2745518:HU722_RS26615
uniprot id: A0A8H9YRG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2745518:HU722 RS26475
gene id: 2745518:HU722_RS26475
uniprot id: A0A8H9YRW4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2745518:HU722 RS07725
gene id: 2745518:HU722_RS07725
uniprot id: A0A8I0D165
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS07635
gene id: 2745518:HU722_RS07635
uniprot id: A0A8H9Z2A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2745518:HU722 RS05100
gene id: 2745518:HU722_RS05100
uniprot id: A0A8I0D2S7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2745518:HU722 RS26825
gene id: 2745518:HU722_RS26825
uniprot id: A0A8H9YSV5
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

2745518:HU722 RS10130
gene id: 2745518:HU722_RS10130
uniprot id: A0A8I0CX04
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745518:HU722 RS04995
gene id: 2745518:HU722_RS04995
uniprot id: A0A8I0D2C3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

2745518:HU722 RS28130
gene id: 2745518:HU722_RS28130
uniprot id: A0A8I0D1R2
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

2745518:HU722 RS04710
gene id: 2745518:HU722_RS04710
uniprot id: A0A8H9Z1W9
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

2745518:HU722 RS11745
gene id: 2745518:HU722_RS11745
uniprot id: A0A8H9Z3K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

2745518:HU722 RS02290
gene id: 2745518:HU722_RS02290
uniprot id: A0A8I0D025
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2745518:HU722 RS14325
gene id: 2745518:HU722_RS14325
uniprot id: A0A8H9YY37
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS09715
gene id: 2745518:HU722_RS09715
uniprot id: A0A8H9YT85
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

2745518:HU722 RS05570
gene id: 2745518:HU722_RS05570
uniprot id: A0A8H9YUF8
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

2745518:HU722 RS13095
gene id: 2745518:HU722_RS13095
uniprot id: A0A8H9Z1V3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

2745518:HU722 RS18115
gene id: 2745518:HU722_RS18115
uniprot id: A0A8I0CVV0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

2745518:HU722 RS03325
gene id: 2745518:HU722_RS03325
uniprot id: A0A8H9YMF3
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

2745518:HU722 RS28430
gene id: 2745518:HU722_RS28430
uniprot id: A0A8I0D1L2
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

2745518:HU722 RS01180
gene id: 2745518:HU722_RS01180
uniprot id: A0A8H9YW86
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

2745518:HU722 RS04960
gene id: 2745518:HU722_RS04960
uniprot id: A0A8H9Z2N7
names: Function
names: Similarity
messages: Belongs to the bacterial renalase family.
messages: Catalyzes the oxidation of the 1,2-dihydro- and 1,6-dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P)+. May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers.

2745518:HU722 RS01290
gene id: 2745518:HU722_RS01290
uniprot id: A0A8I0CZ05
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS08315
gene id: 2745518:HU722_RS08315
uniprot id: A0A8F4X1J6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

2745518:HU722 RS09710
gene id: 2745518:HU722_RS09710
uniprot id: A0A8H9YT27
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

2745518:HU722 RS24705
gene id: 2745518:HU722_RS24705
uniprot id: A0A8H9Z0Z9
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS07455
gene id: 2745518:HU722_RS07455
uniprot id: A0A8I0D2K3
names: Similarity
messages: Belongs to the Skp family.

2745518:HU722 RS23505
gene id: 2745518:HU722_RS23505
uniprot id: A0A8I0CTB4
names: Similarity
messages: Belongs to the UPF0234 family.

2745518:HU722 RS10395
gene id: 2745518:HU722_RS10395
uniprot id: A0A8H9Z4R6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

2745518:HU722 RS12955
gene id: 2745518:HU722_RS12955
uniprot id: A0A8H9Z1H1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS25810
gene id: 2745518:HU722_RS25810
uniprot id: A0A8H9YRI5
names: Similarity
messages: Belongs to the histone deacetylase family.

2745518:HU722 RS28740
gene id: 2745518:HU722_RS28740
uniprot id: A0A8I0D0L6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS12180
gene id: 2745518:HU722_RS12180
uniprot id: A0A8I0D0K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

2745518:HU722 RS01285
gene id: 2745518:HU722_RS01285
uniprot id: A0A8I0CZ52
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

2745518:HU722 RS03845
gene id: 2745518:HU722_RS03845
uniprot id: A0A8H9YMX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

2745518:HU722 RS26960
gene id: 2745518:HU722_RS26960
uniprot id: A0A8H9YTF9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

2745518:HU722 RS17715
gene id: 2745518:HU722_RS17715
uniprot id: A0A8H9YS96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

2745518:HU722 RS23725
gene id: 2745518:HU722_RS23725
uniprot id: A0A8H9YN98
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

2745518:HU722 RS18140
gene id: 2745518:HU722_RS18140
uniprot id: A0A8H9YQ36
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS24075
gene id: 2745518:HU722_RS24075
uniprot id: A0A8I0D1E1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

2745518:HU722 RS17325
gene id: 2745518:HU722_RS17325
uniprot id: A0A8H9YQZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS24655
gene id: 2745518:HU722_RS24655
uniprot id: A0A8H9Z1E1
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

2745518:HU722 RS13205
gene id: 2745518:HU722_RS13205
uniprot id: A0A8H9Z0J1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

2745518:HU722 RS19395
gene id: 2745518:HU722_RS19395
uniprot id: A0A8I0D2L8
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS20870
gene id: 2745518:HU722_RS20870
uniprot id: A0A8H9YI45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

2745518:HU722 RS01335
gene id: 2745518:HU722_RS01335
uniprot id: A0A8H9YVH1
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS12880
gene id: 2745518:HU722_RS12880
uniprot id: A0A8H9Z1I2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS03760
gene id: 2745518:HU722_RS03760
uniprot id: A0A8H9YP21
names: Similarity
messages: Belongs to the bacterioferritin family.

2745518:HU722 RS09500
gene id: 2745518:HU722_RS09500
uniprot id: A0A8H9YS74
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS00090
gene id: 2745518:HU722_RS00090
uniprot id: A0A8H9YY55
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2745518:HU722 RS04750
gene id: 2745518:HU722_RS04750
uniprot id: A0A8H9Z126
names: Caution
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

2745518:HU722 RS09585
gene id: 2745518:HU722_RS09585
uniprot id: A0A8H9YRJ2
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

2745518:HU722 RS27895
gene id: 2745518:HU722_RS27895
uniprot id: A0A8H9YS45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

2745518:HU722 RS07910
gene id: 2745518:HU722_RS07910
uniprot id: A0A8H9Z172
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

2745518:HU722 RS08320
gene id: 2745518:HU722_RS08320
uniprot id: A0A8I0CZY8
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

2745518:HU722 RS26465
gene id: 2745518:HU722_RS26465
uniprot id: A0A8H9YRF1
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

2745518:HU722 RS11135
gene id: 2745518:HU722_RS11135
uniprot id: A0A8I0CY59
names: Similarity
messages: Belongs to the GST superfamily.

2745518:HU722 RS02840
gene id: 2745518:HU722_RS02840
uniprot id: A0A8H9YPU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

2745518:HU722 RS17965
gene id: 2745518:HU722_RS17965
uniprot id: A0A8I0CVU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745518:HU722 RS22470
gene id: 2745518:HU722_RS22470
uniprot id: A0A8H9YLW4
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

2745518:HU722 RS03310
gene id: 2745518:HU722_RS03310
uniprot id: A0A8H9YN29
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS20485
gene id: 2745518:HU722_RS20485
uniprot id: A0A8H9YYE9
names: Similarity
messages: Belongs to the allantoicase family.

2745518:HU722 RS05535
gene id: 2745518:HU722_RS05535
uniprot id: A0A8I0CY66
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

2745518:HU722 RS23645
gene id: 2745518:HU722_RS23645
uniprot id: A0A8H9YLZ4
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS01520
gene id: 2745518:HU722_RS01520
uniprot id: A0A8I0D3A8
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS27560
gene id: 2745518:HU722_RS27560
uniprot id: A0A8I0CWU6
names: PTM
messages: Binds 1 heme group per subunit.

2745518:HU722 RS11850
gene id: 2745518:HU722_RS11850
uniprot id: A0A8H9Z0K6
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

2745518:HU722 RS25975
gene id: 2745518:HU722_RS25975
uniprot id: A0A8I0CW28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

2745518:HU722 RS23150
gene id: 2745518:HU722_RS23150
uniprot id: A0A8H9YK38
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

2745518:HU722 RS01310
gene id: 2745518:HU722_RS01310
uniprot id: A0A8H9YWE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

2745518:HU722 RS25980
gene id: 2745518:HU722_RS25980
uniprot id: A0A8F4WWR1
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

2745518:HU722 RS00680
gene id: 2745518:HU722_RS00680
uniprot id: A0A8H9YUM6
names: Similarity
messages: Belongs to the CFA/CMAS family.

2745518:HU722 RS20865
gene id: 2745518:HU722_RS20865
uniprot id: A0A8I0CUJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2745518:HU722 RS15770
gene id: 2745518:HU722_RS15770
uniprot id: A0A8I0CZ06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

2745518:HU722 RS24425
gene id: 2745518:HU722_RS24425
uniprot id: A0A8H9Z0J4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

2745518:HU722 RS02385
gene id: 2745518:HU722_RS02385
uniprot id: A0A8H9YZJ7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

2745518:HU722 RS15780
gene id: 2745518:HU722_RS15780
uniprot id: A0A8I0CZH0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

2745518:HU722 RS09965
gene id: 2745518:HU722_RS09965
uniprot id: A0A8H9YRD7
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: The active site is a redox-active disulfide bond.

2745518:HU722 RS22490
gene id: 2745518:HU722_RS22490
uniprot id: A0A8H9YLF1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2745518:HU722 RS18485
gene id: 2745518:HU722_RS18485
uniprot id: A0A8H9YRE1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

2745518:HU722 RS08155
gene id: 2745518:HU722_RS08155
uniprot id: A0A8I0CZ88
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS18370
gene id: 2745518:HU722_RS18370
uniprot id: A0A8H9YQA4
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Has an organic peroxide-dependent peroxidase activity.

2745518:HU722 RS06190
gene id: 2745518:HU722_RS06190
uniprot id: A0A8H9YV69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

2745518:HU722 RS27080
gene id: 2745518:HU722_RS27080
uniprot id: A0A8H9YR81
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

2745518:HU722 RS27705
gene id: 2745518:HU722_RS27705
uniprot id: A0A8I0CWT6
names: Function
names: Similarity
messages: Belongs to the CitG/MdcB family.
messages: Involved in the formation of 2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase.

2745518:HU722 RS06875
gene id: 2745518:HU722_RS06875
uniprot id: A0A8I0CYN0
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

2745518:HU722 RS12540
gene id: 2745518:HU722_RS12540
uniprot id: A0A8H9Z497
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

2745518:HU722 RS05035
gene id: 2745518:HU722_RS05035
uniprot id: A0A8I0D3B0
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

2745518:HU722 RS15445
gene id: 2745518:HU722_RS15445
uniprot id: A0A8H9YWC1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

2745518:HU722 RS26890
gene id: 2745518:HU722_RS26890
uniprot id: A0A8H9YSD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

2745518:HU722 RS10980
gene id: 2745518:HU722_RS10980
uniprot id: A0A8I0CYP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745518:HU722 RS24125
gene id: 2745518:HU722_RS24125
uniprot id: A0A8F4WX81
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

2745518:HU722 RS24945
gene id: 2745518:HU722_RS24945
uniprot id: A0A8H9YQS6
names: Similarity
messages: Belongs to the SfsA family.

2745518:HU722 RS21090
gene id: 2745518:HU722_RS21090
uniprot id: A0A8I0CUL1
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

2745518:HU722 RS12630
gene id: 2745518:HU722_RS12630
uniprot id: A0A8I0D1A9
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

2745518:HU722 RS27045
gene id: 2745518:HU722_RS27045
uniprot id: A0A8H9YS95
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS07740
gene id: 2745518:HU722_RS07740
uniprot id: A0A8I0D2E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

2745518:HU722 RS24195
gene id: 2745518:HU722_RS24195
uniprot id: A0A8H9Z079
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

2745518:HU722 RS22955
gene id: 2745518:HU722_RS22955
uniprot id: A0A8H9YMW2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS05205
gene id: 2745518:HU722_RS05205
uniprot id: A0A8F5AE74
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

2745518:HU722 RS02055
gene id: 2745518:HU722_RS02055
uniprot id: A0A8I0D042
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS03540
gene id: 2745518:HU722_RS03540
uniprot id: A0A8H9YN02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

2745518:HU722 RS14055
gene id: 2745518:HU722_RS14055
uniprot id: A0A8I0CZN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

2745518:HU722 RS23445
gene id: 2745518:HU722_RS23445
uniprot id: A0A8F5ABA4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

2745518:HU722 RS05020
gene id: 2745518:HU722_RS05020
uniprot id: A0A8I0D2R6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2745518:HU722 RS07575
gene id: 2745518:HU722_RS07575
uniprot id: A0A8H9Z3P2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS25540
gene id: 2745518:HU722_RS25540
uniprot id: A0A8H9YPB5
names: Similarity
messages: Belongs to the peptidase S16 family.

2745518:HU722 RS13610
gene id: 2745518:HU722_RS13610
uniprot id: A0A8I0D0M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

2745518:HU722 RS17275
gene id: 2745518:HU722_RS17275
uniprot id: A0A8I0CWS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS04800
gene id: 2745518:HU722_RS04800
uniprot id: A0A8H9Z2J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial secretin family. T3SS SctC subfamily.
messages: Cell outer membrane
messages: Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane.
messages: Membrane
messages: The core secretion machinery of the T3SS is composed of approximately 20 different proteins, including cytoplasmic components, a base, an export apparatus and a needle. This subunit is part of the base, which anchors the injectisome in the bacterial cell envelope. Forms a stable homooligomeric complex.

2745518:HU722 RS25050
gene id: 2745518:HU722_RS25050
uniprot id: A0A8I0CVX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

2745518:HU722 RS23975
gene id: 2745518:HU722_RS23975
uniprot id: A0A8H9Z0B1
names: Similarity
messages: Belongs to the YkuD family.

2745518:HU722 RS14420
gene id: 2745518:HU722_RS14420
uniprot id: A0A8H9YZM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

2745518:HU722 RS26050
gene id: 2745518:HU722_RS26050
uniprot id: A0A8I0CW33
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

2745518:HU722 RS24190
gene id: 2745518:HU722_RS24190
uniprot id: A0A8H9Z0M2
names: Similarity
messages: Belongs to the HesB/IscA family.

2745518:HU722 RS28590
gene id: 2745518:HU722_RS28590
uniprot id: A0A8I0D0K4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2745518:HU722 RS19800
gene id: 2745518:HU722_RS19800
uniprot id: A0A8I0D236
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS23405
gene id: 2745518:HU722_RS23405
uniprot id: A0A8H9YMQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

2745518:HU722 RS25045
gene id: 2745518:HU722_RS25045
uniprot id: A0A8I0CVB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

2745518:HU722 RS06475
gene id: 2745518:HU722_RS06475
uniprot id: A0A8H9YU73
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

2745518:HU722 RS24040
gene id: 2745518:HU722_RS24040
uniprot id: A0A8H9Z098
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS03575
gene id: 2745518:HU722_RS03575
uniprot id: A0A8I0CVG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

2745518:HU722 RS05295
gene id: 2745518:HU722_RS05295
uniprot id: A0A8H9Z1N2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2745518:HU722 RS13400
gene id: 2745518:HU722_RS13400
uniprot id: A0A8H9YYJ3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

2745518:HU722 RS06955
gene id: 2745518:HU722_RS06955
uniprot id: A0A8H9YXX1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

2745518:HU722 RS05435
gene id: 2745518:HU722_RS05435
uniprot id: A0A8H9YUU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2745518:HU722 RS22590
gene id: 2745518:HU722_RS22590
uniprot id: A0A8I0CUK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

2745518:HU722 RS12460
gene id: 2745518:HU722_RS12460
uniprot id: A0A8H9Z490
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS05530
gene id: 2745518:HU722_RS05530
uniprot id: A0A8I0CXP9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

2745518:HU722 RS11460
gene id: 2745518:HU722_RS11460
uniprot id: A0A8H9YUL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS17905
gene id: 2745518:HU722_RS17905
uniprot id: A0A8I0CWW0
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

2745518:HU722 RS24990
gene id: 2745518:HU722_RS24990
uniprot id: A0A8I0CWJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

2745518:HU722 RS00425
gene id: 2745518:HU722_RS00425
uniprot id: A0A8I0CZL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

2745518:HU722 RS18915
gene id: 2745518:HU722_RS18915
uniprot id: A0A8I0D1C6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS18590
gene id: 2745518:HU722_RS18590
uniprot id: A0A8H9Z2Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

2745518:HU722 RS00970
gene id: 2745518:HU722_RS00970
uniprot id: A0A8H9YUR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

2745518:HU722 RS07790
gene id: 2745518:HU722_RS07790
uniprot id: A0A8H9Z1Z1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2745518:HU722 RS25000
gene id: 2745518:HU722_RS25000
uniprot id: A0A8H9YP43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

2745518:HU722 RS20815
gene id: 2745518:HU722_RS20815
uniprot id: A0A8H9YKX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2745518:HU722 RS12920
gene id: 2745518:HU722_RS12920
uniprot id: A0A8I0D1T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS12305
gene id: 2745518:HU722_RS12305
uniprot id: A0A8H9Z421
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

2745518:HU722 RS25120
gene id: 2745518:HU722_RS25120
uniprot id: A0A8H9YQA0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS14015
gene id: 2745518:HU722_RS14015
uniprot id: A0A8H9YY03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YhhS family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS19260
gene id: 2745518:HU722_RS19260
uniprot id: A0A8H9Z074
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS11040
gene id: 2745518:HU722_RS11040
uniprot id: A0A8H9YTR4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: The active site is a redox-active disulfide bond.

2745518:HU722 RS19845
gene id: 2745518:HU722_RS19845
uniprot id: A0A8H9Z3B0
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

2745518:HU722 RS27015
gene id: 2745518:HU722_RS27015
uniprot id: A0A8I0CXL0
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

2745518:HU722 RS27620
gene id: 2745518:HU722_RS27620
uniprot id: A0A8I0CXG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0312 family. Type 1 subfamily.
messages: Periplasm

2745518:HU722 RS02365
gene id: 2745518:HU722_RS02365
uniprot id: A0A8I0D021
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS08775
gene id: 2745518:HU722_RS08775
uniprot id: A0A8I0D001
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

2745518:HU722 RS15955
gene id: 2745518:HU722_RS15955
uniprot id: A0A8H9YWP5
names: Similarity
messages: Belongs to the disproportionating enzyme family.

2745518:HU722 RS28365
gene id: 2745518:HU722_RS28365
uniprot id: A0A8H9Z1I8
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

2745518:HU722 RS02495
gene id: 2745518:HU722_RS02495
uniprot id: A0A8H9YXF4
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS09580
gene id: 2745518:HU722_RS09580
uniprot id: A0A8H9YRT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

2745518:HU722 RS04705
gene id: 2745518:HU722_RS04705
uniprot id: A0A8H9Z321
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

2745518:HU722 RS22560
gene id: 2745518:HU722_RS22560
uniprot id: A0A8H9YMR3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

2745518:HU722 RS00470
gene id: 2745518:HU722_RS00470
uniprot id: A0A8H9YYU3
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

2745518:HU722 RS17285
gene id: 2745518:HU722_RS17285
uniprot id: A0A8H9YPS8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745518:HU722 RS21790
gene id: 2745518:HU722_RS21790
uniprot id: A0A8H9YLI8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS22230
gene id: 2745518:HU722_RS22230
uniprot id: A0A8H9YJ20
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

2745518:HU722 RS14490
gene id: 2745518:HU722_RS14490
uniprot id: A0A8H9YZT6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS20515
gene id: 2745518:HU722_RS20515
uniprot id: A0A8H9YZC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

2745518:HU722 RS26015
gene id: 2745518:HU722_RS26015
uniprot id: A0A8H9YR63
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

2745518:HU722 RS21145
gene id: 2745518:HU722_RS21145
uniprot id: A0A8I0CS45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2745518:HU722 RS16350
gene id: 2745518:HU722_RS16350
uniprot id: A0A8H9YWH5
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS02195
gene id: 2745518:HU722_RS02195
uniprot id: A0A8H9YXJ4
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

2745518:HU722 RS18830
gene id: 2745518:HU722_RS18830
uniprot id: A0A8H9YYV6
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS20750
gene id: 2745518:HU722_RS20750
uniprot id: A0A8H9YLL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

2745518:HU722 RS21135
gene id: 2745518:HU722_RS21135
uniprot id: A0A8H9YKH4
names: Similarity
messages: Belongs to the peptidase C40 family.

2745518:HU722 RS07310
gene id: 2745518:HU722_RS07310
uniprot id: A0A8I0CZ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS21815
gene id: 2745518:HU722_RS21815
uniprot id: A0A8H9YMJ4
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

2745518:HU722 RS26575
gene id: 2745518:HU722_RS26575
uniprot id: A0A8I0CW68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2745518:HU722 RS00535
gene id: 2745518:HU722_RS00535
uniprot id: A0A8I0CZ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS09100
gene id: 2745518:HU722_RS09100
uniprot id: A0A8H9YTX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS08825
gene id: 2745518:HU722_RS08825
uniprot id: A0A8H9YYU6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

2745518:HU722 RS11415
gene id: 2745518:HU722_RS11415
uniprot id: A0A8H9YTQ7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745518:HU722 RS22745
gene id: 2745518:HU722_RS22745
uniprot id: A0A8I0CU51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

2745518:HU722 RS20275
gene id: 2745518:HU722_RS20275
uniprot id: A0A8H9YZZ4
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS09180
gene id: 2745518:HU722_RS09180
uniprot id: A0A8H9YSS8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

2745518:HU722 RS19195
gene id: 2745518:HU722_RS19195
uniprot id: A0A8H9YZM4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2745518:HU722 RS21540
gene id: 2745518:HU722_RS21540
uniprot id: A0A8H9YIM4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745518:HU722 RS17220
gene id: 2745518:HU722_RS17220
uniprot id: A0A8H9YQ52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS18190
gene id: 2745518:HU722_RS18190
uniprot id: A0A8I0CVV6
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS18585
gene id: 2745518:HU722_RS18585
uniprot id: A0A8H9Z2Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS18495
gene id: 2745518:HU722_RS18495
uniprot id: A0A8I0CVX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2745518:HU722 RS28530
gene id: 2745518:HU722_RS28530
uniprot id: A0A8H9Z257
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

2745518:HU722 RS18405
gene id: 2745518:HU722_RS18405
uniprot id: A0A8H9YRD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

2745518:HU722 RS08820
gene id: 2745518:HU722_RS08820
uniprot id: A0A8F5AEU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

2745518:HU722 RS07510
gene id: 2745518:HU722_RS07510
uniprot id: A0A8H9Z3E8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

2745518:HU722 RS11250
gene id: 2745518:HU722_RS11250
uniprot id: A0A8H9YUQ5
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS16830
gene id: 2745518:HU722_RS16830
uniprot id: A0A8H9Z406
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS00925
gene id: 2745518:HU722_RS00925
uniprot id: A0A8I0CYL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

2745518:HU722 RS23520
gene id: 2745518:HU722_RS23520
uniprot id: A0A8I0CUR2
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

2745518:HU722 RS17570
gene id: 2745518:HU722_RS17570
uniprot id: A0A8H9YS58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS07865
gene id: 2745518:HU722_RS07865
uniprot id: A0A8H9Z202
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS01580
gene id: 2745518:HU722_RS01580
uniprot id: A0A8H9Z2Y1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745518:HU722 RS07800
gene id: 2745518:HU722_RS07800
uniprot id: A0A8I0D169
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS02480
gene id: 2745518:HU722_RS02480
uniprot id: A0A8H9YYF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2745518:HU722 RS16955
gene id: 2745518:HU722_RS16955
uniprot id: A0A8H9Z4S1
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

2745518:HU722 RS08325
gene id: 2745518:HU722_RS08325
uniprot id: A0A8I0D0D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2745518:HU722 RS05695
gene id: 2745518:HU722_RS05695
uniprot id: A0A8H9YST7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS24605
gene id: 2745518:HU722_RS24605
uniprot id: A0A8I0D238
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS23895
gene id: 2745518:HU722_RS23895
uniprot id: A0A8F4WX42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

2745518:HU722 RS21380
gene id: 2745518:HU722_RS21380
uniprot id: A0A8I0CUA3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745518:HU722 RS13840
gene id: 2745518:HU722_RS13840
uniprot id: A0A8I0D253
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745518:HU722 RS26215
gene id: 2745518:HU722_RS26215
uniprot id: A0A8H9YPI5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS26630
gene id: 2745518:HU722_RS26630
uniprot id: A0A8H9YQU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2745518:HU722 RS24980
gene id: 2745518:HU722_RS24980
uniprot id: A0A8I0CVV8
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

2745518:HU722 RS23785
gene id: 2745518:HU722_RS23785
uniprot id: A0A8H9YMJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2745518:HU722 RS17895
gene id: 2745518:HU722_RS17895
uniprot id: A0A8I0CWE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

2745518:HU722 RS02160
gene id: 2745518:HU722_RS02160
uniprot id: A0A8H9YZM2
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

2745518:HU722 RS06000
gene id: 2745518:HU722_RS06000
uniprot id: A0A8I0CYE1
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

2745518:HU722 RS06165
gene id: 2745518:HU722_RS06165
uniprot id: A0A8H9YT65
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

2745518:HU722 RS01030
gene id: 2745518:HU722_RS01030
uniprot id: A0A8H9YWA5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

2745518:HU722 RS28630
gene id: 2745518:HU722_RS28630
uniprot id: A0A8H9YZ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

2745518:HU722 RS08265
gene id: 2745518:HU722_RS08265
uniprot id: A0A8H9YX64
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS26945
gene id: 2745518:HU722_RS26945
uniprot id: A0A8I0CWZ0
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

2745518:HU722 RS10510
gene id: 2745518:HU722_RS10510
uniprot id: A0A8H9YTY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

2745518:HU722 RS16020
gene id: 2745518:HU722_RS16020
uniprot id: A0A8H9YWZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS23175
gene id: 2745518:HU722_RS23175
uniprot id: A0A8H9YMM7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

2745518:HU722 RS23035
gene id: 2745518:HU722_RS23035
uniprot id: A0A8H9YMX2
names: Similarity
messages: Belongs to the GST superfamily.

2745518:HU722 RS17425
gene id: 2745518:HU722_RS17425
uniprot id: A0A8I0CWA6
names: Similarity
messages: Belongs to the FGGY kinase family.

2745518:HU722 RS21085
gene id: 2745518:HU722_RS21085
uniprot id: A0A8I0CU73
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

2745518:HU722 RS26650
gene id: 2745518:HU722_RS26650
uniprot id: A0A8I0CW74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2745518:HU722 RS06280
gene id: 2745518:HU722_RS06280
uniprot id: A0A8I0CX82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS07430
gene id: 2745518:HU722_RS07430
uniprot id: A0A8H9Z293
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS24870
gene id: 2745518:HU722_RS24870
uniprot id: A0A8H9YQR6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

2745518:HU722 RS15425
gene id: 2745518:HU722_RS15425
uniprot id: A0A8H9YWB6
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS00155
gene id: 2745518:HU722_RS00155
uniprot id: A0A8H9YXT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

2745518:HU722 RS09565
gene id: 2745518:HU722_RS09565
uniprot id: A0A8H9YT99
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

2745518:HU722 RS28250
gene id: 2745518:HU722_RS28250
uniprot id: A0A8H9Z0R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS01345
gene id: 2745518:HU722_RS01345
uniprot id: A0A8H9YUJ5
names: Similarity
messages: Belongs to the SCO1/2 family.

2745518:HU722 RS08655
gene id: 2745518:HU722_RS08655
uniprot id: A0A8H9YXC8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS00415
gene id: 2745518:HU722_RS00415
uniprot id: A0A8H9YYU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS25055
gene id: 2745518:HU722_RS25055
uniprot id: A0A8I0CVW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

2745518:HU722 RS18395
gene id: 2745518:HU722_RS18395
uniprot id: A0A8H9YRV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

2745518:HU722 RS28230
gene id: 2745518:HU722_RS28230
uniprot id: A0A8H9Z2E0
names: Similarity
messages: Belongs to the glutamine synthetase family.

2745518:HU722 RS18005
gene id: 2745518:HU722_RS18005
uniprot id: A0A8H9YQP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745518:HU722 RS24240
gene id: 2745518:HU722_RS24240
uniprot id: A0A8H9Z115
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS11115
gene id: 2745518:HU722_RS11115
uniprot id: A0A8H9YTQ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

2745518:HU722 RS24725
gene id: 2745518:HU722_RS24725
uniprot id: A0A8H9Z2Q1
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

2745518:HU722 RS21710
gene id: 2745518:HU722_RS21710
uniprot id: A0A8H9YKK2
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

2745518:HU722 RS26735
gene id: 2745518:HU722_RS26735
uniprot id: A0A8H9YTJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS27065
gene id: 2745518:HU722_RS27065
uniprot id: A0A8H9YSG6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745518:HU722 RS01840
gene id: 2745518:HU722_RS01840
uniprot id: A0A8H9Z0X4
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS21465
gene id: 2745518:HU722_RS21465
uniprot id: A0A8H9YIK8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

2745518:HU722 RS22790
gene id: 2745518:HU722_RS22790
uniprot id: A0A8H9YM11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2745518:HU722 RS07405
gene id: 2745518:HU722_RS07405
uniprot id: A0A8H9Z1V2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2745518:HU722 RS03535
gene id: 2745518:HU722_RS03535
uniprot id: A0A8H9YNR1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

2745518:HU722 RS26545
gene id: 2745518:HU722_RS26545
uniprot id: A0A8H9YRA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

2745518:HU722 RS17475
gene id: 2745518:HU722_RS17475
uniprot id: A0A8H9YRH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

2745518:HU722 RS24765
gene id: 2745518:HU722_RS24765
uniprot id: A0A8H9Z0L6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

2745518:HU722 RS28290
gene id: 2745518:HU722_RS28290
uniprot id: A0A8H9Z1K0
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

2745518:HU722 RS10185
gene id: 2745518:HU722_RS10185
uniprot id: A0A8H9Z2E7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745518:HU722 RS15655
gene id: 2745518:HU722_RS15655
uniprot id: A0A8H9YX43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

2745518:HU722 RS25135
gene id: 2745518:HU722_RS25135
uniprot id: A0A8F5ACP7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

2745518:HU722 RS28715
gene id: 2745518:HU722_RS28715
uniprot id: A0A8H9YYP5
names: Similarity
messages: Belongs to the P(II) protein family.

2745518:HU722 RS04640
gene id: 2745518:HU722_RS04640
uniprot id: A0A8H9Z4Y6
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

2745518:HU722 RS12120
gene id: 2745518:HU722_RS12120
uniprot id: A0A8I0D1R4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745518:HU722 RS01985
gene id: 2745518:HU722_RS01985
uniprot id: A0A8F4WY93
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS14530
gene id: 2745518:HU722_RS14530
uniprot id: A0A8I0D0V0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

2745518:HU722 RS15590
gene id: 2745518:HU722_RS15590
uniprot id: A0A8H9YXG6
names: Similarity
messages: Belongs to the type IB topoisomerase family.

2745518:HU722 RS18280
gene id: 2745518:HU722_RS18280
uniprot id: A0A8I0CWY2
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

2745518:HU722 RS17860
gene id: 2745518:HU722_RS17860
uniprot id: A0A8H9YRB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

2745518:HU722 RS08145
gene id: 2745518:HU722_RS08145
uniprot id: A0A8H9YY47
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

2745518:HU722 RS14405
gene id: 2745518:HU722_RS14405
uniprot id: A0A8H9YYK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

2745518:HU722 RS02200
gene id: 2745518:HU722_RS02200
uniprot id: A0A8I0D0P0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

2745518:HU722 RS22740
gene id: 2745518:HU722_RS22740
uniprot id: A0A8I0CSZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2745518:HU722 RS00365
gene id: 2745518:HU722_RS00365
uniprot id: A0A8F4WY75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

2745518:HU722 RS20655
gene id: 2745518:HU722_RS20655
uniprot id: A0A8H9YHW0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745518:HU722 RS18575
gene id: 2745518:HU722_RS18575
uniprot id: A0A8I0D374
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

2745518:HU722 RS20015
gene id: 2745518:HU722_RS20015
uniprot id: A0A8H9YYC0
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

2745518:HU722 RS21740
gene id: 2745518:HU722_RS21740
uniprot id: A0A8H9YMI3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

2745518:HU722 RS12525
gene id: 2745518:HU722_RS12525
uniprot id: A0A8H9Z2Q0
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

2745518:HU722 RS01130
gene id: 2745518:HU722_RS01130
uniprot id: A0A8H9YUH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

2745518:HU722 RS09385
gene id: 2745518:HU722_RS09385
uniprot id: A0A8I0CX54
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745518:HU722 RS15795
gene id: 2745518:HU722_RS15795
uniprot id: A0A8H9YWU0
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS16255
gene id: 2745518:HU722_RS16255
uniprot id: A0A8H9YXL8
names: Function
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

2745518:HU722 RS00525
gene id: 2745518:HU722_RS00525
uniprot id: A0A8F4WY97
names: Cofactor
messages: Binds 1 zinc ion per subunit.

2745518:HU722 RS11080
gene id: 2745518:HU722_RS11080
uniprot id: A0A8H9YUQ8
names: Similarity
messages: Belongs to the UPF0502 family.

2745518:HU722 RS15890
gene id: 2745518:HU722_RS15890
uniprot id: A0A8I0D083
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S45 family.
messages: Periplasm

2745518:HU722 RS04965
gene id: 2745518:HU722_RS04965
uniprot id: A0A8H9Z1T4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

2745518:HU722 RS03510
gene id: 2745518:HU722_RS03510
uniprot id: A0A8H9YPQ4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2745518:HU722 RS07475
gene id: 2745518:HU722_RS07475
uniprot id: A0A8H9Z1F9
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

2745518:HU722 RS19385
gene id: 2745518:HU722_RS19385
uniprot id: A0A8F4WV96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

2745518:HU722 RS24410
gene id: 2745518:HU722_RS24410
uniprot id: A0A8H9Z1M9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS24610
gene id: 2745518:HU722_RS24610
uniprot id: A0A8I0D250
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

2745518:HU722 RS01465
gene id: 2745518:HU722_RS01465
uniprot id: A0A8H9YVD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ivy family.
messages: Periplasm

2745518:HU722 RS23315
gene id: 2745518:HU722_RS23315
uniprot id: A0A8H9YLH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

2745518:HU722 RS02235
gene id: 2745518:HU722_RS02235
uniprot id: A0A8H9YZL1
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

2745518:HU722 RS17800
gene id: 2745518:HU722_RS17800
uniprot id: A0A8H9YSA7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

2745518:HU722 RS11905
gene id: 2745518:HU722_RS11905
uniprot id: A0A8H9YZU1
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS03765
gene id: 2745518:HU722_RS03765
uniprot id: A0A8H9YNN3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS07125
gene id: 2745518:HU722_RS07125
uniprot id: A0A8H9YWY7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2745518:HU722 RS20930
gene id: 2745518:HU722_RS20930
uniprot id: A0A8I0CTD8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

2745518:HU722 RS26550
gene id: 2745518:HU722_RS26550
uniprot id: A0A8H9YRX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2745518:HU722 RS16685
gene id: 2745518:HU722_RS16685
uniprot id: A0A8I0D396
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2745518:HU722 RS03675
gene id: 2745518:HU722_RS03675
uniprot id: A0A8H9YPI3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS10105
gene id: 2745518:HU722_RS10105
uniprot id: A0A8H9YRL8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

2745518:HU722 RS11220
gene id: 2745518:HU722_RS11220
uniprot id: A0A8I0CXJ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS19685
gene id: 2745518:HU722_RS19685
uniprot id: A0A8H9Z2D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS20800
gene id: 2745518:HU722_RS20800
uniprot id: A0A8H9YI12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

2745518:HU722 RS28730
gene id: 2745518:HU722_RS28730
uniprot id: A0A8I0D062
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

2745518:HU722 RS10015
gene id: 2745518:HU722_RS10015
uniprot id: A0A8H9YT50
names: Similarity
messages: Belongs to the pirin family.

2745518:HU722 RS00105
gene id: 2745518:HU722_RS00105
uniprot id: A0A8H9YZ85
names: Similarity
messages: Belongs to the UPF0758 family.

2745518:HU722 RS05640
gene id: 2745518:HU722_RS05640
uniprot id: A0A8H9YTX4
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

2745518:HU722 RS17400
gene id: 2745518:HU722_RS17400
uniprot id: A0A8H9YS59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS26590
gene id: 2745518:HU722_RS26590
uniprot id: A0A8H9YPM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2745518:HU722 RS18720
gene id: 2745518:HU722_RS18720
uniprot id: A0A8H9YZT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 83 family.
messages: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

2745518:HU722 RS17065
gene id: 2745518:HU722_RS17065
uniprot id: A0A8H9YQ33
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS28480
gene id: 2745518:HU722_RS28480
uniprot id: A0A8H9Z0N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS26285
gene id: 2745518:HU722_RS26285
uniprot id: A0A8I0CWS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS12210
gene id: 2745518:HU722_RS12210
uniprot id: A0A8H9YZV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

2745518:HU722 RS09070
gene id: 2745518:HU722_RS09070
uniprot id: A0A8H9YRR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

2745518:HU722 RS26500
gene id: 2745518:HU722_RS26500
uniprot id: A0A8I0CW61
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2745518:HU722 RS08150
gene id: 2745518:HU722_RS08150
uniprot id: A0A8H9YZ53
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS11185
gene id: 2745518:HU722_RS11185
uniprot id: A0A8H9YTT3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS20900
gene id: 2745518:HU722_RS20900
uniprot id: A0A8H9YL65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

2745518:HU722 RS26135
gene id: 2745518:HU722_RS26135
uniprot id: A0A8I0CWR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

2745518:HU722 RS03315
gene id: 2745518:HU722_RS03315
uniprot id: A0A8H9YMT9
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS04740
gene id: 2745518:HU722_RS04740
uniprot id: A0A8H9Z1H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS02330
gene id: 2745518:HU722_RS02330
uniprot id: A0A8H9YXU9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS06465
gene id: 2745518:HU722_RS06465
uniprot id: A0A8H9YTA1
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

2745518:HU722 RS25955
gene id: 2745518:HU722_RS25955
uniprot id: A0A8H9YQL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745518:HU722 RS01560
gene id: 2745518:HU722_RS01560
uniprot id: A0A8H9Z4H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

2745518:HU722 RS06070
gene id: 2745518:HU722_RS06070
uniprot id: A0A8I0CYA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS08355
gene id: 2745518:HU722_RS08355
uniprot id: A0A8H9YY80
names: Similarity
messages: Belongs to the SAICAR synthetase family.

2745518:HU722 RS25800
gene id: 2745518:HU722_RS25800
uniprot id: A0A8H9YRM2
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

2745518:HU722 RS15410
gene id: 2745518:HU722_RS15410
uniprot id: A0A8H9YV91
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

2745518:HU722 RS14130
gene id: 2745518:HU722_RS14130
uniprot id: A0A8I0CZN8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

2745518:HU722 RS09755
gene id: 2745518:HU722_RS09755
uniprot id: A0A8I0CX29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

2745518:HU722 RS25630
gene id: 2745518:HU722_RS25630
uniprot id: A0A8F4WXV0
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.

2745518:HU722 RS19865
gene id: 2745518:HU722_RS19865
uniprot id: A0A8H9Z3L8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

2745518:HU722 RS13005
gene id: 2745518:HU722_RS13005
uniprot id: A0A8I0D194
names: Function
messages: Binds zinc. Could be an important component of the zinc-balancing mechanism.

2745518:HU722 RS22915
gene id: 2745518:HU722_RS22915
uniprot id: A0A8I0CUY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

2745518:HU722 RS16110
gene id: 2745518:HU722_RS16110
uniprot id: A0A8H9YWP3
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

2745518:HU722 RS23440
gene id: 2745518:HU722_RS23440
uniprot id: A0A8I0CU65
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

2745518:HU722 RS05185
gene id: 2745518:HU722_RS05185
uniprot id: A0A8H9Z243
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

2745518:HU722 RS21335
gene id: 2745518:HU722_RS21335
uniprot id: A0A8H9YK82
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS04110
gene id: 2745518:HU722_RS04110
uniprot id: A0A8I0CUB2
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS26505
gene id: 2745518:HU722_RS26505
uniprot id: A0A8I0CWN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2745518:HU722 RS14620
gene id: 2745518:HU722_RS14620
uniprot id: A0A8H9Z188
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

2745518:HU722 RS09960
gene id: 2745518:HU722_RS09960
uniprot id: A0A8H9YRE7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

2745518:HU722 RS21745
gene id: 2745518:HU722_RS21745
uniprot id: A0A8I0CSE0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS08100
gene id: 2745518:HU722_RS08100
uniprot id: A0A8I0D0G6
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

2745518:HU722 RS00150
gene id: 2745518:HU722_RS00150
uniprot id: A0A8H9YXS3
names: Similarity
messages: Belongs to the YicC/YloC family.

2745518:HU722 RS07470
gene id: 2745518:HU722_RS07470
uniprot id: A0A8H9Z1G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

2745518:HU722 RS25750
gene id: 2745518:HU722_RS25750
uniprot id: A0A8I0CW09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

2745518:HU722 RS14315
gene id: 2745518:HU722_RS14315
uniprot id: A0A8H9YY76
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2745518:HU722 RS17320
gene id: 2745518:HU722_RS17320
uniprot id: A0A8H9YS50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS23550
gene id: 2745518:HU722_RS23550
uniprot id: A0A8H9YMA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

2745518:HU722 RS22565
gene id: 2745518:HU722_RS22565
uniprot id: A0A8H9YLG1
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

2745518:HU722 RS24000
gene id: 2745518:HU722_RS24000
uniprot id: A0A8F5ACH7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745518:HU722 RS00715
gene id: 2745518:HU722_RS00715
uniprot id: A0A8H9YVN3
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflK subfamily.

2745518:HU722 RS03355
gene id: 2745518:HU722_RS03355
uniprot id: A0A8H9YPS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS11700
gene id: 2745518:HU722_RS11700
uniprot id: A0A8I0D277
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS00315
gene id: 2745518:HU722_RS00315
uniprot id: A0A8H9YY89
names: Similarity
messages: Belongs to the ClpA/ClpB family.

2745518:HU722 RS08280
gene id: 2745518:HU722_RS08280
uniprot id: A0A8H9YY72
names: Function
names: Similarity
messages: An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
messages: Belongs to the SdhE FAD assembly factor family.

2745518:HU722 RS12475
gene id: 2745518:HU722_RS12475
uniprot id: A0A8H9Z3F3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS26195
gene id: 2745518:HU722_RS26195
uniprot id: A0A8I0CW48
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS24690
gene id: 2745518:HU722_RS24690
uniprot id: A0A8H9Z0K7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS06920
gene id: 2745518:HU722_RS06920
uniprot id: A0A8H9YVX8
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

2745518:HU722 RS13750
gene id: 2745518:HU722_RS13750
uniprot id: A0A8I0D3D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP.
messages: Membrane

2745518:HU722 RS27680
gene id: 2745518:HU722_RS27680
uniprot id: A0A8H9YR80
names: Similarity
messages: Belongs to the fabD family.

2745518:HU722 RS11810
gene id: 2745518:HU722_RS11810
uniprot id: A0A8I0D151
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

2745518:HU722 RS19935
gene id: 2745518:HU722_RS19935
uniprot id: A0A8I0D0Z7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745518:HU722 RS21195
gene id: 2745518:HU722_RS21195
uniprot id: A0A8H9YLV6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

2745518:HU722 RS23050
gene id: 2745518:HU722_RS23050
uniprot id: A0A8I0CT59
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS03060
gene id: 2745518:HU722_RS03060
uniprot id: A0A8H9YNL9
names: Subunit
messages: Monomer.

2745518:HU722 RS05095
gene id: 2745518:HU722_RS05095
uniprot id: A0A8I0D2S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

2745518:HU722 RS26130
gene id: 2745518:HU722_RS26130
uniprot id: A0A8I0CWL1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

2745518:HU722 RS28600
gene id: 2745518:HU722_RS28600
uniprot id: A0A8H9YXM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

2745518:HU722 RS28570
gene id: 2745518:HU722_RS28570
uniprot id: A0A8I0D2W1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

2745518:HU722 RS25145
gene id: 2745518:HU722_RS25145
uniprot id: A0A8I0CWC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

2745518:HU722 RS10205
gene id: 2745518:HU722_RS10205
uniprot id: A0A8I0D2J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS19200
gene id: 2745518:HU722_RS19200
uniprot id: A0A8H9YZ66
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2745518:HU722 RS27255
gene id: 2745518:HU722_RS27255
uniprot id: A0A8I0CWW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS27010
gene id: 2745518:HU722_RS27010
uniprot id: A0A8H9YR77
names: Function
names: Similarity
messages: Belongs to the PqqA family.
messages: Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.

2745518:HU722 RS00145
gene id: 2745518:HU722_RS00145
uniprot id: A0A8I0D0S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

2745518:HU722 RS20595
gene id: 2745518:HU722_RS20595
uniprot id: A0A8F4WUI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

2745518:HU722 RS19080
gene id: 2745518:HU722_RS19080
uniprot id: A0A8I0D0M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS17795
gene id: 2745518:HU722_RS17795
uniprot id: A0A8H9YRM0
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS18885
gene id: 2745518:HU722_RS18885
uniprot id: A0A8H9Z0G5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS05345
gene id: 2745518:HU722_RS05345
uniprot id: A0A8H9Z3B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS09895
gene id: 2745518:HU722_RS09895
uniprot id: A0A8I0CXP3
names: Similarity
messages: Belongs to the MlaA family.

2745518:HU722 RS12370
gene id: 2745518:HU722_RS12370
uniprot id: A0A8I0D2B7
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

2745518:HU722 RS05615
gene id: 2745518:HU722_RS05615
uniprot id: A0A8I0CYB7
names: Subcellular Location Annotation
messages: Cytoplasm

2745518:HU722 RS07890
gene id: 2745518:HU722_RS07890
uniprot id: A0A8I0D2F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2.A.1.15) family.
messages: Membrane

2745518:HU722 RS03195
gene id: 2745518:HU722_RS03195
uniprot id: A0A8I0CV46
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

2745518:HU722 RS02745
gene id: 2745518:HU722_RS02745
uniprot id: A0A8I0CV74
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS23720
gene id: 2745518:HU722_RS23720
uniprot id: A0A8H9YM05
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745518:HU722 RS11480
gene id: 2745518:HU722_RS11480
uniprot id: A0A8H9YUM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

2745518:HU722 RS06940
gene id: 2745518:HU722_RS06940
uniprot id: A0A8I0CZB2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

2745518:HU722 RS14210
gene id: 2745518:HU722_RS14210
uniprot id: A0A8I0CZP3
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

2745518:HU722 RS23690
gene id: 2745518:HU722_RS23690
uniprot id: A0A8H9YLB5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

2745518:HU722 RS04880
gene id: 2745518:HU722_RS04880
uniprot id: A0A8H9Z2H7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

2745518:HU722 RS21835
gene id: 2745518:HU722_RS21835
uniprot id: A0A8I0CUD9
names: Similarity
messages: Belongs to the citrate synthase family.

2745518:HU722 RS03985
gene id: 2745518:HU722_RS03985
uniprot id: A0A8H9YNY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

2745518:HU722 RS25130
gene id: 2745518:HU722_RS25130
uniprot id: A0A8I0CVC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

2745518:HU722 RS21630
gene id: 2745518:HU722_RS21630
uniprot id: A0A8H9YJJ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

2745518:HU722 RS12105
gene id: 2745518:HU722_RS12105
uniprot id: A0A8I0D0K0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2745518:HU722 RS17865
gene id: 2745518:HU722_RS17865
uniprot id: A0A8H9YRR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

2745518:HU722 RS01305
gene id: 2745518:HU722_RS01305
uniprot id: A0A8I0CXW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

2745518:HU722 RS15230
gene id: 2745518:HU722_RS15230
uniprot id: A0A8I0CYA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnF family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

2745518:HU722 RS05660
gene id: 2745518:HU722_RS05660
uniprot id: A0A8H9YTV0
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

2745518:HU722 RS01150
gene id: 2745518:HU722_RS01150
uniprot id: A0A8I0CYJ8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS15765
gene id: 2745518:HU722_RS15765
uniprot id: A0A8I0CYD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

2745518:HU722 RS26755
gene id: 2745518:HU722_RS26755
uniprot id: A0A8H9YT31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

2745518:HU722 RS25160
gene id: 2745518:HU722_RS25160
uniprot id: A0A8H9YP61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

2745518:HU722 RS05450
gene id: 2745518:HU722_RS05450
uniprot id: A0A8I0CXP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

2745518:HU722 RS26965
gene id: 2745518:HU722_RS26965
uniprot id: A0A8H9YSB2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2745518:HU722 RS18645
gene id: 2745518:HU722_RS18645
uniprot id: A0A8H9YZU9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS26905
gene id: 2745518:HU722_RS26905
uniprot id: A0A8H9YT16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

2745518:HU722 RS22990
gene id: 2745518:HU722_RS22990
uniprot id: A0A8I0CUM7
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

2745518:HU722 RS18425
gene id: 2745518:HU722_RS18425
uniprot id: A0A8I0CWG7
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

2745518:HU722 RS03140
gene id: 2745518:HU722_RS03140
uniprot id: A0A8H9YPQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
messages: Cell membrane
messages: K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.

2745518:HU722 RS11535
gene id: 2745518:HU722_RS11535
uniprot id: A0A8H9Z2N0
names: Similarity
messages: Belongs to the glutamate synthase family.

2745518:HU722 RS00010
gene id: 2745518:HU722_RS00010
uniprot id: A0A8H9YXR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS06015
gene id: 2745518:HU722_RS06015
uniprot id: A0A8H9YT49
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2745518:HU722 RS01315
gene id: 2745518:HU722_RS01315
uniprot id: A0A8H9YVF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS02605
gene id: 2745518:HU722_RS02605
uniprot id: A0A8I0CZD4
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

2745518:HU722 RS06085
gene id: 2745518:HU722_RS06085
uniprot id: A0A8H9YSW8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS15450
gene id: 2745518:HU722_RS15450
uniprot id: A0A8H9YXA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

2745518:HU722 RS12320
gene id: 2745518:HU722_RS12320
uniprot id: A0A8H9Z3M6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS07435
gene id: 2745518:HU722_RS07435
uniprot id: A0A8F5AE04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

2745518:HU722 RS00700
gene id: 2745518:HU722_RS00700
uniprot id: A0A8I0CYM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

2745518:HU722 RS01220
gene id: 2745518:HU722_RS01220
uniprot id: A0A8I0CYJ5
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

2745518:HU722 RS11425
gene id: 2745518:HU722_RS11425
uniprot id: A0A8H9YTK4
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS02945
gene id: 2745518:HU722_RS02945
uniprot id: A0A8H9YMK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

2745518:HU722 RS13955
gene id: 2745518:HU722_RS13955
uniprot id: A0A8H9YZL6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS04715
gene id: 2745518:HU722_RS04715
uniprot id: A0A8H9Z380
names: Similarity
messages: Belongs to the PhzF family.

2745518:HU722 RS14195
gene id: 2745518:HU722_RS14195
uniprot id: A0A8H9Z038
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS04860
gene id: 2745518:HU722_RS04860
uniprot id: A0A8I0D152
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

2745518:HU722 RS08410
gene id: 2745518:HU722_RS08410
uniprot id: A0A8I0D0J2
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS09675
gene id: 2745518:HU722_RS09675
uniprot id: A0A8I0CXK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

2745518:HU722 RS09900
gene id: 2745518:HU722_RS09900
uniprot id: A0A8I0CXJ5
names: Similarity
messages: Belongs to the MlaA family.

2745518:HU722 RS10705
gene id: 2745518:HU722_RS10705
uniprot id: A0A8H9YUV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS27960
gene id: 2745518:HU722_RS27960
uniprot id: A0A8H9YSE6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

2745518:HU722 RS15470
gene id: 2745518:HU722_RS15470
uniprot id: A0A8I0CZF1
names: Similarity
messages: Belongs to the UDPGP type 2 family.

2745518:HU722 RS05040
gene id: 2745518:HU722_RS05040
uniprot id: A0A8H9Z2X4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

2745518:HU722 RS00320
gene id: 2745518:HU722_RS00320
uniprot id: A0A8H9YYS4
names: Similarity
messages: Belongs to the VgrG protein family.

2745518:HU722 RS28385
gene id: 2745518:HU722_RS28385
uniprot id: A0A8H9Z1H6
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

2745518:HU722 RS01555
gene id: 2745518:HU722_RS01555
uniprot id: A0A8H9Z560
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

2745518:HU722 RS26335
gene id: 2745518:HU722_RS26335
uniprot id: A0A8H9YRQ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

2745518:HU722 RS10695
gene id: 2745518:HU722_RS10695
uniprot id: A0A8I0CXM5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745518:HU722 RS13920
gene id: 2745518:HU722_RS13920
uniprot id: A0A8I0D0Q8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745518:HU722 RS16035
gene id: 2745518:HU722_RS16035
uniprot id: A0A8H9YWL5
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS24405
gene id: 2745518:HU722_RS24405
uniprot id: A0A8H9Z283
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS19410
gene id: 2745518:HU722_RS19410
uniprot id: A0A8H9Z2J9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

2745518:HU722 RS09590
gene id: 2745518:HU722_RS09590
uniprot id: A0A8H9YRJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

2745518:HU722 RS08795
gene id: 2745518:HU722_RS08795
uniprot id: A0A8H9YXD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

2745518:HU722 RS04895
gene id: 2745518:HU722_RS04895
uniprot id: A0A8H9Z1F7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

2745518:HU722 RS27025
gene id: 2745518:HU722_RS27025
uniprot id: A0A8I0CWY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PqqD family.
messages: Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
messages: Monomer. Interacts with PqqE.

2745518:HU722 RS21575
gene id: 2745518:HU722_RS21575
uniprot id: A0A8H9YME1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS26180
gene id: 2745518:HU722_RS26180
uniprot id: A0A8H9YQP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

2745518:HU722 RS11890
gene id: 2745518:HU722_RS11890
uniprot id: A0A8I0D173
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS07565
gene id: 2745518:HU722_RS07565
uniprot id: A0A8H9Z356
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

2745518:HU722 RS10620
gene id: 2745518:HU722_RS10620
uniprot id: A0A8I0CXN0
names: Similarity
messages: Belongs to the asparagine synthetase family.

2745518:HU722 RS18620
gene id: 2745518:HU722_RS18620
uniprot id: A0A8H9Z510
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS23355
gene id: 2745518:HU722_RS23355
uniprot id: A0A8I0CU95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2745518:HU722 RS23335
gene id: 2745518:HU722_RS23335
uniprot id: A0A8H9YN08
names: Similarity
messages: Belongs to the carbamate kinase family.

2745518:HU722 RS26075
gene id: 2745518:HU722_RS26075
uniprot id: A0A8H9YPV1
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS24760
gene id: 2745518:HU722_RS24760
uniprot id: A0A8I0D256
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS01090
gene id: 2745518:HU722_RS01090
uniprot id: A0A8H9YVI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

2745518:HU722 RS24160
gene id: 2745518:HU722_RS24160
uniprot id: A0A8H9Z267
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

2745518:HU722 RS25030
gene id: 2745518:HU722_RS25030
uniprot id: A0A8H9YRB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

2745518:HU722 RS12730
gene id: 2745518:HU722_RS12730
uniprot id: A0A8H9Z246
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS23455
gene id: 2745518:HU722_RS23455
uniprot id: A0A8H9YKC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

2745518:HU722 RS19450
gene id: 2745518:HU722_RS19450
uniprot id: A0A8H9Z3E2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

2745518:HU722 RS01195
gene id: 2745518:HU722_RS01195
uniprot id: A0A8H9YUP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

2745518:HU722 RS17985
gene id: 2745518:HU722_RS17985
uniprot id: A0A8I0CX17
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745518:HU722 RS06405
gene id: 2745518:HU722_RS06405
uniprot id: A0A8H9YUT4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS16755
gene id: 2745518:HU722_RS16755
uniprot id: A0A8H9Z418
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS06340
gene id: 2745518:HU722_RS06340
uniprot id: A0A8H9YV87
names: Similarity
messages: Belongs to the peptidase S13 family.

2745518:HU722 RS01670
gene id: 2745518:HU722_RS01670
uniprot id: A0A8H9Z0Z3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS05180
gene id: 2745518:HU722_RS05180
uniprot id: A0A8H9Z2I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS19115
gene id: 2745518:HU722_RS19115
uniprot id: A0A8H9YZN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2745518:HU722 RS28345
gene id: 2745518:HU722_RS28345
uniprot id: A0A8I0D1N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS18490
gene id: 2745518:HU722_RS18490
uniprot id: A0A8H9YSJ0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2745518:HU722 RS04540
gene id: 2745518:HU722_RS04540
uniprot id: A0A8H9YMD7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS02815
gene id: 2745518:HU722_RS02815
uniprot id: A0A8I0CV52
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745518:HU722 RS01095
gene id: 2745518:HU722_RS01095
uniprot id: A0A8H9YWM5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

2745518:HU722 RS00920
gene id: 2745518:HU722_RS00920
uniprot id: A0A8I0CYL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

2745518:HU722 RS09935
gene id: 2745518:HU722_RS09935
uniprot id: A0A8H9YT01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

2745518:HU722 RS21000
gene id: 2745518:HU722_RS21000
uniprot id: A0A8I0CTH7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS24735
gene id: 2745518:HU722_RS24735
uniprot id: A0A8H9Z2J8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS16010
gene id: 2745518:HU722_RS16010
uniprot id: A0A8H9YYB3
names: Similarity
messages: Belongs to the histone deacetylase family.

2745518:HU722 RS07840
gene id: 2745518:HU722_RS07840
uniprot id: A0A8H9Z1K8
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS04730
gene id: 2745518:HU722_RS04730
uniprot id: A0A8H9Z2R8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745518:HU722 RS24835
gene id: 2745518:HU722_RS24835
uniprot id: A0A8I0D261
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

2745518:HU722 RS25665
gene id: 2745518:HU722_RS25665
uniprot id: A0A8I0CVF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS04020
gene id: 2745518:HU722_RS04020
uniprot id: A0A8I0CVD4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2745518:HU722 RS00710
gene id: 2745518:HU722_RS00710
uniprot id: A0A8H9YWL9
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

2745518:HU722 RS13060
gene id: 2745518:HU722_RS13060
uniprot id: A0A8H9YZW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS19525
gene id: 2745518:HU722_RS19525
uniprot id: A0A8H9Z3J3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

2745518:HU722 RS12645
gene id: 2745518:HU722_RS12645
uniprot id: A0A8H9Z0X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BexD/CtrA/VexA family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS20905
gene id: 2745518:HU722_RS20905
uniprot id: A0A8H9YM49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

2745518:HU722 RS26110
gene id: 2745518:HU722_RS26110
uniprot id: A0A8F4WWM8
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

2745518:HU722 RS09530
gene id: 2745518:HU722_RS09530
uniprot id: A0A8I0CX48
names: Similarity
messages: Belongs to the OsmC/Ohr family.

2745518:HU722 RS03755
gene id: 2745518:HU722_RS03755
uniprot id: A0A8H9YNU5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745518:HU722 RS19635
gene id: 2745518:HU722_RS19635
uniprot id: A0A8H9Z3H9
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS23430
gene id: 2745518:HU722_RS23430
uniprot id: A0A8I0CTA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2745518:HU722 RS18230
gene id: 2745518:HU722_RS18230
uniprot id: A0A8H9YQS3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2745518:HU722 RS19130
gene id: 2745518:HU722_RS19130
uniprot id: A0A8H9YYQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS04785
gene id: 2745518:HU722_RS04785
uniprot id: A0A8H9Z304
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Membrane

2745518:HU722 RS27845
gene id: 2745518:HU722_RS27845
uniprot id: A0A8I0CXF2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

2745518:HU722 RS00440
gene id: 2745518:HU722_RS00440
uniprot id: A0A8I0D0Q0
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

2745518:HU722 RS24145
gene id: 2745518:HU722_RS24145
uniprot id: A0A8I0D1E2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

2745518:HU722 RS22570
gene id: 2745518:HU722_RS22570
uniprot id: A0A8H9YMV6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2745518:HU722 RS18270
gene id: 2745518:HU722_RS18270
uniprot id: A0A8I0CWG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS13905
gene id: 2745518:HU722_RS13905
uniprot id: A0A8I0CZM3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. RhamD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR).
messages: Homooctamer; tetramer of dimers.
messages: Reaction proceeds via a syn dehydration.

2745518:HU722 RS21205
gene id: 2745518:HU722_RS21205
uniprot id: A0A8H9YM93
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS17845
gene id: 2745518:HU722_RS17845
uniprot id: A0A8H9YQ24
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS21890
gene id: 2745518:HU722_RS21890
uniprot id: A0A8H9YMK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

2745518:HU722 RS07150
gene id: 2745518:HU722_RS07150
uniprot id: A0A8I0CZU8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2745518:HU722 RS11205
gene id: 2745518:HU722_RS11205
uniprot id: A0A8I0CYM7
names: Similarity
messages: Belongs to the type IA topoisomerase family.

2745518:HU722 RS23985
gene id: 2745518:HU722_RS23985
uniprot id: A0A8I0D1Z1
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

2745518:HU722 RS00170
gene id: 2745518:HU722_RS00170
uniprot id: A0A8H9YYQ9
names: Similarity
messages: Belongs to the RutC family.

2745518:HU722 RS28675
gene id: 2745518:HU722_RS28675
uniprot id: A0A8H9YXN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

2745518:HU722 RS14140
gene id: 2745518:HU722_RS14140
uniprot id: A0A8I0D0C5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2745518:HU722 RS08850
gene id: 2745518:HU722_RS08850
uniprot id: A0A8H9Z3X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

2745518:HU722 RS18085
gene id: 2745518:HU722_RS18085
uniprot id: A0A8H9YRE3
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS14120
gene id: 2745518:HU722_RS14120
uniprot id: A0A8H9YYY9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745518:HU722 RS00195
gene id: 2745518:HU722_RS00195
uniprot id: A0A8H9YZT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

2745518:HU722 RS02510
gene id: 2745518:HU722_RS02510
uniprot id: A0A8I0D0H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

2745518:HU722 RS20915
gene id: 2745518:HU722_RS20915
uniprot id: A0A8H9YM71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

2745518:HU722 RS04675
gene id: 2745518:HU722_RS04675
uniprot id: A0A8H9Z148
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS24995
gene id: 2745518:HU722_RS24995
uniprot id: A0A8H9YP49
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

2745518:HU722 RS03005
gene id: 2745518:HU722_RS03005
uniprot id: A0A8H9YNY1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS16275
gene id: 2745518:HU722_RS16275
uniprot id: A0A8H9YWI7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

2745518:HU722 RS26920
gene id: 2745518:HU722_RS26920
uniprot id: A0A8H9YRJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

2745518:HU722 RS19330
gene id: 2745518:HU722_RS19330
uniprot id: A0A8H9Z0R4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

2745518:HU722 RS00935
gene id: 2745518:HU722_RS00935
uniprot id: A0A8H9YWJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

2745518:HU722 RS03490
gene id: 2745518:HU722_RS03490
uniprot id: A0A8I0CVG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

2745518:HU722 RS17955
gene id: 2745518:HU722_RS17955
uniprot id: A0A8H9YR74
names: Cofactor
messages: Can also use Mn(2+) ion.

2745518:HU722 RS01690
gene id: 2745518:HU722_RS01690
uniprot id: A0A8I0D2B8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745518:HU722 RS05245
gene id: 2745518:HU722_RS05245
uniprot id: A0A8H9Z3X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

2745518:HU722 RS24570
gene id: 2745518:HU722_RS24570
uniprot id: A0A8H9Z217
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

2745518:HU722 RS20625
gene id: 2745518:HU722_RS20625
uniprot id: A0A8F4WVV0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745518:HU722 RS17970
gene id: 2745518:HU722_RS17970
uniprot id: A0A8I0CWE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745518:HU722 RS22725
gene id: 2745518:HU722_RS22725
uniprot id: A0A8H9YMS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS17885
gene id: 2745518:HU722_RS17885
uniprot id: A0A8H9YSA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2745518:HU722 RS27860
gene id: 2745518:HU722_RS27860
uniprot id: A0A8I0CWS7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS20805
gene id: 2745518:HU722_RS20805
uniprot id: A0A8H9YIQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

2745518:HU722 RS02615
gene id: 2745518:HU722_RS02615
uniprot id: A0A8H9YYC1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

2745518:HU722 RS07505
gene id: 2745518:HU722_RS07505
uniprot id: A0A8H9Z297
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

2745518:HU722 RS22635
gene id: 2745518:HU722_RS22635
uniprot id: A0A8H9YMS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

2745518:HU722 RS02155
gene id: 2745518:HU722_RS02155
uniprot id: A0A8H9YYJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

2745518:HU722 RS08480
gene id: 2745518:HU722_RS08480
uniprot id: A0A8I0CZZ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS21820
gene id: 2745518:HU722_RS21820
uniprot id: A0A8I0CSF7
names: Similarity
messages: Belongs to the PrpD family.

2745518:HU722 RS05505
gene id: 2745518:HU722_RS05505
uniprot id: A0A8H9YUV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS05655
gene id: 2745518:HU722_RS05655
uniprot id: A0A8H9YUX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

2745518:HU722 RS17440
gene id: 2745518:HU722_RS17440
uniprot id: A0A8I0CWY4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS01865
gene id: 2745518:HU722_RS01865
uniprot id: A0A8I0D129
names: Function
names: Similarity
messages: Belongs to the CsgG family.
messages: May be involved in the biogenesis of curli organelles.

2745518:HU722 RS16055
gene id: 2745518:HU722_RS16055
uniprot id: A0A8I0CZM0
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS08865
gene id: 2745518:HU722_RS08865
uniprot id: A0A8H9Z4Q1
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

2745518:HU722 RS00600
gene id: 2745518:HU722_RS00600
uniprot id: A0A8H9YUN5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

2745518:HU722 RS00390
gene id: 2745518:HU722_RS00390
uniprot id: A0A8H9YY99
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS06530
gene id: 2745518:HU722_RS06530
uniprot id: A0A8H9YT60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

2745518:HU722 RS28540
gene id: 2745518:HU722_RS28540
uniprot id: A0A8H9Z1F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

2745518:HU722 RS06845
gene id: 2745518:HU722_RS06845
uniprot id: A0A8H9YVY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS17230
gene id: 2745518:HU722_RS17230
uniprot id: A0A8H9YR37
names: Similarity
messages: Belongs to the YkuD family.

2745518:HU722 RS12705
gene id: 2745518:HU722_RS12705
uniprot id: A0A8I0D1B5
names: Similarity
messages: Belongs to the pirin family.

2745518:HU722 RS27410
gene id: 2745518:HU722_RS27410
uniprot id: A0A8I0CWA7
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

2745518:HU722 RS05810
gene id: 2745518:HU722_RS05810
uniprot id: A0A8H9YTW3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

2745518:HU722 RS08525
gene id: 2745518:HU722_RS08525
uniprot id: A0A8H9YYR5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS09210
gene id: 2745518:HU722_RS09210
uniprot id: A0A8H9YRZ0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

2745518:HU722 RS03055
gene id: 2745518:HU722_RS03055
uniprot id: A0A8H9YPV3
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS19960
gene id: 2745518:HU722_RS19960
uniprot id: A0A8H9YZ48
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS07770
gene id: 2745518:HU722_RS07770
uniprot id: A0A8H9Z1Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

2745518:HU722 RS15180
gene id: 2745518:HU722_RS15180
uniprot id: A0A8H9YV61
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745518:HU722 RS20980
gene id: 2745518:HU722_RS20980
uniprot id: A0A8H9YM62
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

2745518:HU722 RS13855
gene id: 2745518:HU722_RS13855
uniprot id: A0A8H9YXZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

2745518:HU722 RS20105
gene id: 2745518:HU722_RS20105
uniprot id: A0A8H9YY88
names: Similarity
messages: Belongs to the BolA/IbaG family.

2745518:HU722 RS24080
gene id: 2745518:HU722_RS24080
uniprot id: A0A8I0D0S3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

2745518:HU722 RS22785
gene id: 2745518:HU722_RS22785
uniprot id: A0A8H9YL84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

2745518:HU722 RS26200
gene id: 2745518:HU722_RS26200
uniprot id: A0A8I0CW43
names: Similarity
messages: Belongs to the PspA/IM30 family.

2745518:HU722 RS04000
gene id: 2745518:HU722_RS04000
uniprot id: A0A8H9YMK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

2745518:HU722 RS13080
gene id: 2745518:HU722_RS13080
uniprot id: A0A8I0D188
names: Similarity
messages: Belongs to the transglycosylase Slt family.

2745518:HU722 RS25115
gene id: 2745518:HU722_RS25115
uniprot id: A0A8H9YRD0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

2745518:HU722 RS12185
gene id: 2745518:HU722_RS12185
uniprot id: A0A8I0D171
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

2745518:HU722 RS00370
gene id: 2745518:HU722_RS00370
uniprot id: A0A8I0D0U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

2745518:HU722 RS00985
gene id: 2745518:HU722_RS00985
uniprot id: A0A8I0CZ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS21830
gene id: 2745518:HU722_RS21830
uniprot id: A0A8I0CTM5
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

2745518:HU722 RS09925
gene id: 2745518:HU722_RS09925
uniprot id: A0A8H9YSH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

2745518:HU722 RS21535
gene id: 2745518:HU722_RS21535
uniprot id: A0A8I0CUP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS21810
gene id: 2745518:HU722_RS21810
uniprot id: A0A8H9YL07
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

2745518:HU722 RS23810
gene id: 2745518:HU722_RS23810
uniprot id: A0A8I0CUD3
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS10095
gene id: 2745518:HU722_RS10095
uniprot id: A0A8H9YSL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2745518:HU722 RS24825
gene id: 2745518:HU722_RS24825
uniprot id: A0A8I0D1L3
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

2745518:HU722 RS00065
gene id: 2745518:HU722_RS00065
uniprot id: A0A8I0D0M1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS13800
gene id: 2745518:HU722_RS13800
uniprot id: A0A8H9Z339
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS20470
gene id: 2745518:HU722_RS20470
uniprot id: A0A8I0D138
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

2745518:HU722 RS11860
gene id: 2745518:HU722_RS11860
uniprot id: A0A8H9Z190
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

2745518:HU722 RS10995
gene id: 2745518:HU722_RS10995
uniprot id: A0A8I0CXK8
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

2745518:HU722 RS26930
gene id: 2745518:HU722_RS26930
uniprot id: A0A8H9YR83
names: Similarity
messages: Belongs to the UPF0229 family.

2745518:HU722 RS08915
gene id: 2745518:HU722_RS08915
uniprot id: A0A8H9YRT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

2745518:HU722 RS24135
gene id: 2745518:HU722_RS24135
uniprot id: A0A8I0D1Z8
names: Similarity
messages: Belongs to the YfgM family.

2745518:HU722 RS17490
gene id: 2745518:HU722_RS17490
uniprot id: A0A8H9YS44
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS13240
gene id: 2745518:HU722_RS13240
uniprot id: A0A8F4X2D6
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS00465
gene id: 2745518:HU722_RS00465
uniprot id: A0A8H9YYA1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS02370
gene id: 2745518:HU722_RS02370
uniprot id: A0A8I0CZE5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

2745518:HU722 RS08340
gene id: 2745518:HU722_RS08340
uniprot id: A0A8H9YX74
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homodimer.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

2745518:HU722 RS26490
gene id: 2745518:HU722_RS26490
uniprot id: A0A8I0CVL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2745518:HU722 RS14560
gene id: 2745518:HU722_RS14560
uniprot id: A0A8H9Z212
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily.
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate.
messages: Homotetramer; dimer of dimers.

2745518:HU722 RS28320
gene id: 2745518:HU722_RS28320
uniprot id: A0A8H9Z0Q1
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS15575
gene id: 2745518:HU722_RS15575
uniprot id: A0A8H9YWD9
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

2745518:HU722 RS25935
gene id: 2745518:HU722_RS25935
uniprot id: A0A8H9YQQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

2745518:HU722 RS20125
gene id: 2745518:HU722_RS20125
uniprot id: A0A8H9YZX6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2745518:HU722 RS16335
gene id: 2745518:HU722_RS16335
uniprot id: A0A8H9YWV7
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS00115
gene id: 2745518:HU722_RS00115
uniprot id: A0A8H9YYR1
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

2745518:HU722 RS25520
gene id: 2745518:HU722_RS25520
uniprot id: A0A8F4WWK5
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS26270
gene id: 2745518:HU722_RS26270
uniprot id: A0A8I0CW53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2745518:HU722 RS16825
gene id: 2745518:HU722_RS16825
uniprot id: A0A8H9Z2K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS15905
gene id: 2745518:HU722_RS15905
uniprot id: A0A8I0CZM9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS22415
gene id: 2745518:HU722_RS22415
uniprot id: A0A8H9YLD8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

2745518:HU722 RS13295
gene id: 2745518:HU722_RS13295
uniprot id: A0A8I0CZW9
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS09785
gene id: 2745518:HU722_RS09785
uniprot id: A0A8H9YT21
names: Function
names: Similarity
messages: Belongs to the ribose 1,5-bisphosphokinase family.
messages: Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).

2745518:HU722 RS05930
gene id: 2745518:HU722_RS05930
uniprot id: A0A8H9YSW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS15375
gene id: 2745518:HU722_RS15375
uniprot id: A0A8H9YXA4
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

2745518:HU722 RS19850
gene id: 2745518:HU722_RS19850
uniprot id: A0A8H9Z352
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

2745518:HU722 RS00955
gene id: 2745518:HU722_RS00955
uniprot id: A0A8H9YWB7
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

2745518:HU722 RS07985
gene id: 2745518:HU722_RS07985
uniprot id: A0A8H9Z3Y4
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS22680
gene id: 2745518:HU722_RS22680
uniprot id: A0A8I0CUK8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

2745518:HU722 RS01110
gene id: 2745518:HU722_RS01110
uniprot id: A0A8H9YVK0
names: Similarity
messages: Belongs to the DprA/Smf family.

2745518:HU722 RS02655
gene id: 2745518:HU722_RS02655
uniprot id: A0A8I0CVX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

2745518:HU722 RS08090
gene id: 2745518:HU722_RS08090
uniprot id: A0A8I0CZX3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS27050
gene id: 2745518:HU722_RS27050
uniprot id: A0A8H9YTF5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745518:HU722 RS10385
gene id: 2745518:HU722_RS10385
uniprot id: A0A8H9Z4F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS26555
gene id: 2745518:HU722_RS26555
uniprot id: A0A8H9YQT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2745518:HU722 RS10310
gene id: 2745518:HU722_RS10310
uniprot id: A0A8I0D1S0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2745518:HU722 RS02380
gene id: 2745518:HU722_RS02380
uniprot id: A0A8H9YYF1
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

2745518:HU722 RS17815
gene id: 2745518:HU722_RS17815
uniprot id: A0A8I0CVT0
names: Similarity
messages: Belongs to the DsrF/TusC family.

2745518:HU722 RS22315
gene id: 2745518:HU722_RS22315
uniprot id: A0A8H9YL12
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

2745518:HU722 RS26530
gene id: 2745518:HU722_RS26530
uniprot id: A0A8H9YQ99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

2745518:HU722 RS20875
gene id: 2745518:HU722_RS20875
uniprot id: A0A8H9YI52
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

2745518:HU722 RS19420
gene id: 2745518:HU722_RS19420
uniprot id: A0A8H9Z2M7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS24215
gene id: 2745518:HU722_RS24215
uniprot id: A0A8I0D1X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS27820
gene id: 2745518:HU722_RS27820
uniprot id: A0A8H9YS56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

2745518:HU722 RS06200
gene id: 2745518:HU722_RS06200
uniprot id: A0A8H9YV31
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

2745518:HU722 RS17745
gene id: 2745518:HU722_RS17745
uniprot id: A0A8I0CWC7
names: Subcellular Location Annotation
messages: Cell inner membrane

2745518:HU722 RS24880
gene id: 2745518:HU722_RS24880
uniprot id: A0A8H9YRA4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS25735
gene id: 2745518:HU722_RS25735
uniprot id: A0A8H9YRH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS19995
gene id: 2745518:HU722_RS19995
uniprot id: A0A8I0D0E2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS05410
gene id: 2745518:HU722_RS05410
uniprot id: A0A8H9YTU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS26655
gene id: 2745518:HU722_RS26655
uniprot id: A0A8I0CWQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

2745518:HU722 RS01060
gene id: 2745518:HU722_RS01060
uniprot id: A0A8I0CZ64
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2745518:HU722 RS19275
gene id: 2745518:HU722_RS19275
uniprot id: A0A8H9YZ56
names: Similarity
messages: Belongs to the asparaginase 1 family.

2745518:HU722 RS20065
gene id: 2745518:HU722_RS20065
uniprot id: A0A8H9YZ69
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS26970
gene id: 2745518:HU722_RS26970
uniprot id: A0A8H9YTG5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

2745518:HU722 RS28985
gene id: 2745518:HU722_RS28985
uniprot id: A0A8H9YRN9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

2745518:HU722 RS07620
gene id: 2745518:HU722_RS07620
uniprot id: A0A8H9Z1I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS04835
gene id: 2745518:HU722_RS04835
uniprot id: A0A8I0D2D8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

2745518:HU722 RS07945
gene id: 2745518:HU722_RS07945
uniprot id: A0A8H9Z358
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

2745518:HU722 RS15760
gene id: 2745518:HU722_RS15760
uniprot id: A0A8H9YXE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

2745518:HU722 RS18420
gene id: 2745518:HU722_RS18420
uniprot id: A0A8I0CWH1
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

2745518:HU722 RS21255
gene id: 2745518:HU722_RS21255
uniprot id: A0A8H9YJ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

2745518:HU722 RS17935
gene id: 2745518:HU722_RS17935
uniprot id: A0A8H9YRC1
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

2745518:HU722 RS25150
gene id: 2745518:HU722_RS25150
uniprot id: A0A8I0CWK5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

2745518:HU722 RS06855
gene id: 2745518:HU722_RS06855
uniprot id: A0A8I0CZW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS15635
gene id: 2745518:HU722_RS15635
uniprot id: A0A8H9YVC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745518:HU722 RS25695
gene id: 2745518:HU722_RS25695
uniprot id: A0A8H9YPC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS18775
gene id: 2745518:HU722_RS18775
uniprot id: A0A8I0D0S9
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS02350
gene id: 2745518:HU722_RS02350
uniprot id: A0A8I0D0N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

2745518:HU722 RS21485
gene id: 2745518:HU722_RS21485
uniprot id: A0A8H9YLD0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

2745518:HU722 RS24930
gene id: 2745518:HU722_RS24930
uniprot id: A0A8H9YPF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2745518:HU722 RS22465
gene id: 2745518:HU722_RS22465
uniprot id: A0A8H9YL32
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2745518:HU722 RS14125
gene id: 2745518:HU722_RS14125
uniprot id: A0A8H9Z010
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS09400
gene id: 2745518:HU722_RS09400
uniprot id: A0A8H9YSP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

2745518:HU722 RS13065
gene id: 2745518:HU722_RS13065
uniprot id: A0A8H9YZY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS23560
gene id: 2745518:HU722_RS23560
uniprot id: A0A8H9YMG7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

2745518:HU722 RS03135
gene id: 2745518:HU722_RS03135
uniprot id: A0A8H9YNK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

2745518:HU722 RS28395
gene id: 2745518:HU722_RS28395
uniprot id: A0A8H9Z135
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

2745518:HU722 RS02320
gene id: 2745518:HU722_RS02320
uniprot id: A0A8H9YZ58
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

2745518:HU722 RS06335
gene id: 2745518:HU722_RS06335
uniprot id: A0A8H9YUL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS25755
gene id: 2745518:HU722_RS25755
uniprot id: A0A8I0CWI4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS26625
gene id: 2745518:HU722_RS26625
uniprot id: A0A8H9YRY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2745518:HU722 RS20795
gene id: 2745518:HU722_RS20795
uniprot id: A0A8H9YI16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

2745518:HU722 RS28415
gene id: 2745518:HU722_RS28415
uniprot id: A0A8I0D272
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

2745518:HU722 RS23500
gene id: 2745518:HU722_RS23500
uniprot id: A0A8H9YN67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

2745518:HU722 RS21130
gene id: 2745518:HU722_RS21130
uniprot id: A0A8H9YM82
names: Similarity
messages: Belongs to the peptidase C40 family.

2745518:HU722 RS17930
gene id: 2745518:HU722_RS17930
uniprot id: A0A8H9YQN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

2745518:HU722 RS27005
gene id: 2745518:HU722_RS27005
uniprot id: A0A8H9YR89
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. It is thought that this protein is a protease that cleaves peptides bond in a small peptide (gene pqqA), providing the glutamate and tyrosine residues which are necessary for the synthesis of PQQ.

2745518:HU722 RS08835
gene id: 2745518:HU722_RS08835
uniprot id: A0A8I0D2U7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

2745518:HU722 RS24285
gene id: 2745518:HU722_RS24285
uniprot id: A0A8H9Z062
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS23030
gene id: 2745518:HU722_RS23030
uniprot id: A0A8H9YM88
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS02410
gene id: 2745518:HU722_RS02410
uniprot id: A0A8H9YXH7
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

2745518:HU722 RS20290
gene id: 2745518:HU722_RS20290
uniprot id: A0A8H9YZ91
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

2745518:HU722 RS22860
gene id: 2745518:HU722_RS22860
uniprot id: A0A8H9YLA1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS26805
gene id: 2745518:HU722_RS26805
uniprot id: A0A8I0CWE3
names: Similarity
messages: Belongs to the TrpC family.

2745518:HU722 RS13965
gene id: 2745518:HU722_RS13965
uniprot id: A0A8H9Z015
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

2745518:HU722 RS23125
gene id: 2745518:HU722_RS23125
uniprot id: A0A8I0CT71
names: Similarity
messages: Belongs to the OprB family.

2745518:HU722 RS19295
gene id: 2745518:HU722_RS19295
uniprot id: A0A8I0D199
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

2745518:HU722 RS26570
gene id: 2745518:HU722_RS26570
uniprot id: A0A8I0CW71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2745518:HU722 RS28330
gene id: 2745518:HU722_RS28330
uniprot id: A0A8H9Z0Q8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

2745518:HU722 RS11505
gene id: 2745518:HU722_RS11505
uniprot id: A0A8I0CYP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

2745518:HU722 RS10110
gene id: 2745518:HU722_RS10110
uniprot id: A0A8H9YRD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

2745518:HU722 RS25590
gene id: 2745518:HU722_RS25590
uniprot id: A0A8F4WXQ2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

2745518:HU722 RS10950
gene id: 2745518:HU722_RS10950
uniprot id: A0A8H9YUU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

2745518:HU722 RS16510
gene id: 2745518:HU722_RS16510
uniprot id: A0A8I0D045
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

2745518:HU722 RS09230
gene id: 2745518:HU722_RS09230
uniprot id: A0A8I0CXN7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

2745518:HU722 RS03865
gene id: 2745518:HU722_RS03865
uniprot id: A0A8I0CVP4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS23695
gene id: 2745518:HU722_RS23695
uniprot id: A0A8H9YLN5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745518:HU722 RS06375
gene id: 2745518:HU722_RS06375
uniprot id: A0A8I0CYG7
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

2745518:HU722 RS21010
gene id: 2745518:HU722_RS21010
uniprot id: A0A8I0CU67
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

2745518:HU722 RS10530
gene id: 2745518:HU722_RS10530
uniprot id: A0A8F4X150
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

2745518:HU722 RS03210
gene id: 2745518:HU722_RS03210
uniprot id: A0A8H9YNJ9
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

2745518:HU722 RS25870
gene id: 2745518:HU722_RS25870
uniprot id: A0A8H9YR29
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS03515
gene id: 2745518:HU722_RS03515
uniprot id: A0A8H9YNG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

2745518:HU722 RS20820
gene id: 2745518:HU722_RS20820
uniprot id: A0A8H9YLN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2745518:HU722 RS20745
gene id: 2745518:HU722_RS20745
uniprot id: A0A8H9YKV3
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

2745518:HU722 RS07705
gene id: 2745518:HU722_RS07705
uniprot id: A0A8H9Z2L3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

2745518:HU722 RS03145
gene id: 2745518:HU722_RS03145
uniprot id: A0A8H9YP20
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745518:HU722 RS13740
gene id: 2745518:HU722_RS13740
uniprot id: A0A8H9Z310
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Divalent metal cations. Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.

2745518:HU722 RS24210
gene id: 2745518:HU722_RS24210
uniprot id: A0A8I0D1Z4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

2745518:HU722 RS01665
gene id: 2745518:HU722_RS01665
uniprot id: A0A8H9Z1D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS20675
gene id: 2745518:HU722_RS20675
uniprot id: A0A8H9YLK9
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

2745518:HU722 RS25140
gene id: 2745518:HU722_RS25140
uniprot id: A0A8I0CVW7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

2745518:HU722 RS09930
gene id: 2745518:HU722_RS09930
uniprot id: A0A8H9YTM4
names: Similarity
messages: Belongs to the citrate synthase family.

2745518:HU722 RS16900
gene id: 2745518:HU722_RS16900
uniprot id: A0A8H9Z2J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS21840
gene id: 2745518:HU722_RS21840
uniprot id: A0A8I0CUR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

2745518:HU722 RS21560
gene id: 2745518:HU722_RS21560
uniprot id: A0A8H9YLE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

2745518:HU722 RS21095
gene id: 2745518:HU722_RS21095
uniprot id: A0A8H9YIA9
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

2745518:HU722 RS16380
gene id: 2745518:HU722_RS16380
uniprot id: A0A8H9YYH2
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS00460
gene id: 2745518:HU722_RS00460
uniprot id: A0A8H9YXY2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

2745518:HU722 RS02475
gene id: 2745518:HU722_RS02475
uniprot id: A0A8H9YZ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS15620
gene id: 2745518:HU722_RS15620
uniprot id: A0A8I0CZG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

2745518:HU722 RS07540
gene id: 2745518:HU722_RS07540
uniprot id: A0A8H9Z1G7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

2745518:HU722 RS19085
gene id: 2745518:HU722_RS19085
uniprot id: A0A8I0D010
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

2745518:HU722 RS25100
gene id: 2745518:HU722_RS25100
uniprot id: A0A8H9YQE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

2745518:HU722 RS07660
gene id: 2745518:HU722_RS07660
uniprot id: A0A8H9Z3H0
names: Similarity
messages: Belongs to the GST superfamily.

2745518:HU722 RS15420
gene id: 2745518:HU722_RS15420
uniprot id: A0A8H9YVN5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS26940
gene id: 2745518:HU722_RS26940
uniprot id: A0A8I0CXG8
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

2745518:HU722 RS03935
gene id: 2745518:HU722_RS03935
uniprot id: A0A8H9YM77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the precorrin methyltransferase family.
messages: Homodimer.
messages: Methylates precorrin-2 at the C-20 position to produce precorrin-3A.

2745518:HU722 RS03000
gene id: 2745518:HU722_RS03000
uniprot id: A0A8H9YPB4
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS22610
gene id: 2745518:HU722_RS22610
uniprot id: A0A8H9YKI3
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS10030
gene id: 2745518:HU722_RS10030
uniprot id: A0A8H9YRM8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

2745518:HU722 RS13405
gene id: 2745518:HU722_RS13405
uniprot id: A0A8H9YYJ2
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS24130
gene id: 2745518:HU722_RS24130
uniprot id: A0A8H9Z092
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

2745518:HU722 RS27980
gene id: 2745518:HU722_RS27980
uniprot id: A0A8H9YR40
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS05690
gene id: 2745518:HU722_RS05690
uniprot id: A0A8I0CYC0
names: Similarity
messages: Belongs to the BolA/IbaG family.

2745518:HU722 RS20965
gene id: 2745518:HU722_RS20965
uniprot id: A0A8H9YL19
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

2745518:HU722 RS28405
gene id: 2745518:HU722_RS28405
uniprot id: A0A8H9Z0P5
names: Subcellular Location Annotation
messages: Nucleus

2745518:HU722 RS21155
gene id: 2745518:HU722_RS21155
uniprot id: A0A8I0CTG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

2745518:HU722 RS22670
gene id: 2745518:HU722_RS22670
uniprot id: A0A8I0CU44
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

2745518:HU722 RS06170
gene id: 2745518:HU722_RS06170
uniprot id: A0A8H9YTG1
names: Similarity
messages: Belongs to the UPF0246 family.

2745518:HU722 RS02690
gene id: 2745518:HU722_RS02690
uniprot id: A0A8H9YPX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

2745518:HU722 RS00975
gene id: 2745518:HU722_RS00975
uniprot id: A0A8H9YUJ4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745518:HU722 RS23705
gene id: 2745518:HU722_RS23705
uniprot id: A0A8H9YMU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS23165
gene id: 2745518:HU722_RS23165
uniprot id: A0A8H9YLE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LysR transcriptional regulatory family.
messages: Controls the transcription of genes involved in arginine and lysine metabolism.
messages: Homodimer.

2745518:HU722 RS06605
gene id: 2745518:HU722_RS06605
uniprot id: A0A8H9YWF7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

2745518:HU722 RS23825
gene id: 2745518:HU722_RS23825
uniprot id: A0A8I0CV35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

2745518:HU722 RS17980
gene id: 2745518:HU722_RS17980
uniprot id: A0A8I0CWW3
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

2745518:HU722 RS28475
gene id: 2745518:HU722_RS28475
uniprot id: A0A8H9Z0M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS17710
gene id: 2745518:HU722_RS17710
uniprot id: A0A8H9YRK9
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

2745518:HU722 RS26705
gene id: 2745518:HU722_RS26705
uniprot id: A0A8H9YR10
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

2745518:HU722 RS19120
gene id: 2745518:HU722_RS19120
uniprot id: A0A8H9YZ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2745518:HU722 RS07075
gene id: 2745518:HU722_RS07075
uniprot id: A0A8I0CZV1
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

2745518:HU722 RS28195
gene id: 2745518:HU722_RS28195
uniprot id: A0A8H9Z378
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS05190
gene id: 2745518:HU722_RS05190
uniprot id: A0A8H9Z1Q0
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS04535
gene id: 2745518:HU722_RS04535
uniprot id: A0A8H9YMN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

2745518:HU722 RS18040
gene id: 2745518:HU722_RS18040
uniprot id: A0A8I0CVU5
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

2745518:HU722 RS18195
gene id: 2745518:HU722_RS18195
uniprot id: A0A8I0CWF8
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS24695
gene id: 2745518:HU722_RS24695
uniprot id: A0A8H9Z0K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS09975
gene id: 2745518:HU722_RS09975
uniprot id: A0A8I0CXJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

2745518:HU722 RS02710
gene id: 2745518:HU722_RS02710
uniprot id: A0A8H9YNA6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS20490
gene id: 2745518:HU722_RS20490
uniprot id: A0A8H9YYW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ureidoglycolate lyase family.
messages: Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.
messages: Homodimer.

2745518:HU722 RS05030
gene id: 2745518:HU722_RS05030
uniprot id: A0A8I0D3B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

2745518:HU722 RS14410
gene id: 2745518:HU722_RS14410
uniprot id: A0A8H9YZ16
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

2745518:HU722 RS12240
gene id: 2745518:HU722_RS12240
uniprot id: A0A8H9Z1Z2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS05485
gene id: 2745518:HU722_RS05485
uniprot id: A0A8H9YT78
names: Similarity
messages: Belongs to the DapA family.

2745518:HU722 RS13505
gene id: 2745518:HU722_RS13505
uniprot id: A0A8H9Z036
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

2745518:HU722 RS07415
gene id: 2745518:HU722_RS07415
uniprot id: A0A8H9Z337
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

2745518:HU722 RS08705
gene id: 2745518:HU722_RS08705
uniprot id: A0A8I0D011
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

2745518:HU722 RS01340
gene id: 2745518:HU722_RS01340
uniprot id: A0A8H9YUV0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

2745518:HU722 RS18330
gene id: 2745518:HU722_RS18330
uniprot id: A0A8H9YRC3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2745518:HU722 RS18500
gene id: 2745518:HU722_RS18500
uniprot id: A0A8I0CWH5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

2745518:HU722 RS04770
gene id: 2745518:HU722_RS04770
uniprot id: A0A8I0D1U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS13835
gene id: 2745518:HU722_RS13835
uniprot id: A0A8H9Z536
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS26080
gene id: 2745518:HU722_RS26080
uniprot id: A0A8H9YQ30
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS10780
gene id: 2745518:HU722_RS10780
uniprot id: A0A8F4X2G5
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

2745518:HU722 RS11840
gene id: 2745518:HU722_RS11840
uniprot id: A0A8H9YZQ0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

2745518:HU722 RS15380
gene id: 2745518:HU722_RS15380
uniprot id: A0A8I0CYB0
names: Similarity
messages: Belongs to the CdaR family.

2745518:HU722 RS04820
gene id: 2745518:HU722_RS04820
uniprot id: A0A8H9Z128
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YscJ lipoprotein family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS15970
gene id: 2745518:HU722_RS15970
uniprot id: A0A8I0D038
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

2745518:HU722 RS02325
gene id: 2745518:HU722_RS02325
uniprot id: A0A8H9YYH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

2745518:HU722 RS04775
gene id: 2745518:HU722_RS04775
uniprot id: A0A8I0D1T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS28690
gene id: 2745518:HU722_RS28690
uniprot id: A0A8H9YY39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

2745518:HU722 RS27775
gene id: 2745518:HU722_RS27775
uniprot id: A0A8I0CXB3
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

2745518:HU722 RS13290
gene id: 2745518:HU722_RS13290
uniprot id: A0A8H9Z0H4
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

2745518:HU722 RS05500
gene id: 2745518:HU722_RS05500
uniprot id: A0A8H9YU99
names: Similarity
messages: Belongs to the UxaA family.

2745518:HU722 RS18660
gene id: 2745518:HU722_RS18660
uniprot id: A0A8H9Z0J5
names: Similarity
messages: Belongs to the FGGY kinase family.

2745518:HU722 RS15405
gene id: 2745518:HU722_RS15405
uniprot id: A0A8H9YV93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

2745518:HU722 RS20850
gene id: 2745518:HU722_RS20850
uniprot id: A0A8I0CTG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS21620
gene id: 2745518:HU722_RS21620
uniprot id: A0A8H9YIN9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS26370
gene id: 2745518:HU722_RS26370
uniprot id: A0A8H9YPK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

2745518:HU722 RS04940
gene id: 2745518:HU722_RS04940
uniprot id: A0A8H9Z2Y2
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

2745518:HU722 RS28225
gene id: 2745518:HU722_RS28225
uniprot id: A0A8H9Z2A2
names: Similarity
messages: Belongs to the glutamine synthetase family.

2745518:HU722 RS02610
gene id: 2745518:HU722_RS02610
uniprot id: A0A8H9YZF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

2745518:HU722 RS04520
gene id: 2745518:HU722_RS04520
uniprot id: A0A8H9YNJ8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2745518:HU722 RS03885
gene id: 2745518:HU722_RS03885
uniprot id: A0A8I0CUD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS24370
gene id: 2745518:HU722_RS24370
uniprot id: A0A8H9Z068
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

2745518:HU722 RS06360
gene id: 2745518:HU722_RS06360
uniprot id: A0A8I0CXV8
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

2745518:HU722 RS16005
gene id: 2745518:HU722_RS16005
uniprot id: A0A8H9YY51
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS00190
gene id: 2745518:HU722_RS00190
uniprot id: A0A8H9YYR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

2745518:HU722 RS19390
gene id: 2745518:HU722_RS19390
uniprot id: A0A8I0D2K4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS05790
gene id: 2745518:HU722_RS05790
uniprot id: A0A8H9YTZ1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745518:HU722 RS22450
gene id: 2745518:HU722_RS22450
uniprot id: A0A8H9YJC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

2745518:HU722 RS03235
gene id: 2745518:HU722_RS03235
uniprot id: A0A8H9YN39
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. KdkA/rfaP family.
messages: Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core.

2745518:HU722 RS07700
gene id: 2745518:HU722_RS07700
uniprot id: A0A8H9Z2S9
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS11765
gene id: 2745518:HU722_RS11765
uniprot id: A0A8H9YZP8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS23195
gene id: 2745518:HU722_RS23195
uniprot id: A0A8H9YN23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

2745518:HU722 RS27115
gene id: 2745518:HU722_RS27115
uniprot id: A0A8H9YTE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

2745518:HU722 RS01885
gene id: 2745518:HU722_RS01885
uniprot id: A0A8H9Z2E8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745518:HU722 RS21825
gene id: 2745518:HU722_RS21825
uniprot id: A0A8I0CTS2
names: Similarity
messages: Belongs to the PrpF family.

2745518:HU722 RS09970
gene id: 2745518:HU722_RS09970
uniprot id: A0A8I0CXP0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

2745518:HU722 RS21520
gene id: 2745518:HU722_RS21520
uniprot id: A0A8I0CTN6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

2745518:HU722 RS24905
gene id: 2745518:HU722_RS24905
uniprot id: A0A8I0CVV3
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

2745518:HU722 RS10760
gene id: 2745518:HU722_RS10760
uniprot id: A0A8I0CY86
names: Similarity
messages: Belongs to the CdaR family.

2745518:HU722 RS24795
gene id: 2745518:HU722_RS24795
uniprot id: A0A8H9Z245
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS07920
gene id: 2745518:HU722_RS07920
uniprot id: A0A8H9Z203
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS28115
gene id: 2745518:HU722_RS28115
uniprot id: A0A8H9Z4M8
names: Similarity
messages: Belongs to the YjiK family.

2745518:HU722 RS12300
gene id: 2745518:HU722_RS12300
uniprot id: A0A8I0D1L7
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS26670
gene id: 2745518:HU722_RS26670
uniprot id: A0A8H9YPP9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS20100
gene id: 2745518:HU722_RS20100
uniprot id: A0A8H9YYC7
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

2745518:HU722 RS23325
gene id: 2745518:HU722_RS23325
uniprot id: A0A8H9YMP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

2745518:HU722 RS08255
gene id: 2745518:HU722_RS08255
uniprot id: A0A8I0D0H9
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

2745518:HU722 RS16280
gene id: 2745518:HU722_RS16280
uniprot id: A0A8I0D061
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

2745518:HU722 RS27420
gene id: 2745518:HU722_RS27420
uniprot id: A0A8H9YS48
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

2745518:HU722 RS11420
gene id: 2745518:HU722_RS11420
uniprot id: A0A8H9YTL3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS24450
gene id: 2745518:HU722_RS24450
uniprot id: A0A8I0D1W1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

2745518:HU722 RS10240
gene id: 2745518:HU722_RS10240
uniprot id: A0A8H9Z401
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS28315
gene id: 2745518:HU722_RS28315
uniprot id: A0A8H9Z146
names: Similarity
messages: Belongs to the band 7/mec-2 family.

2745518:HU722 RS24175
gene id: 2745518:HU722_RS24175
uniprot id: A0A8H9Z1R1
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

2745518:HU722 RS20590
gene id: 2745518:HU722_RS20590
uniprot id: A0A8H9YKP4
names: Similarity
messages: Belongs to the Lgt family.

2745518:HU722 RS27975
gene id: 2745518:HU722_RS27975
uniprot id: A0A8H9YRF6
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS18200
gene id: 2745518:HU722_RS18200
uniprot id: A0A8I0CWF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS03990
gene id: 2745518:HU722_RS03990
uniprot id: A0A8H9YNK1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

2745518:HU722 RS10295
gene id: 2745518:HU722_RS10295
uniprot id: A0A8I0D318
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS26410
gene id: 2745518:HU722_RS26410
uniprot id: A0A8H9YRR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsB sub-subfamily.
messages: Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane

2745518:HU722 RS19890
gene id: 2745518:HU722_RS19890
uniprot id: A0A8H9YZU6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS03475
gene id: 2745518:HU722_RS03475
uniprot id: A0A8H9YMD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

2745518:HU722 RS05495
gene id: 2745518:HU722_RS05495
uniprot id: A0A8H9YUF1
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS20585
gene id: 2745518:HU722_RS20585
uniprot id: A0A8H9YJI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

2745518:HU722 RS17465
gene id: 2745518:HU722_RS17465
uniprot id: A0A8H9YR73
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

2745518:HU722 RS24110
gene id: 2745518:HU722_RS24110
uniprot id: A0A8H9Z124
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS00495
gene id: 2745518:HU722_RS00495
uniprot id: A0A8I0CZL8
names: Similarity
messages: Belongs to the histone deacetylase family.

2745518:HU722 RS08750
gene id: 2745518:HU722_RS08750
uniprot id: A0A8H9YYT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

2745518:HU722 RS02585
gene id: 2745518:HU722_RS02585
uniprot id: A0A8I0D0L8
names: Similarity
messages: Belongs to the peptidase S41A family.

2745518:HU722 RS23620
gene id: 2745518:HU722_RS23620
uniprot id: A0A8H9YLM4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2745518:HU722 RS13895
gene id: 2745518:HU722_RS13895
uniprot id: A0A8F4WRP4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2745518:HU722 RS15260
gene id: 2745518:HU722_RS15260
uniprot id: A0A8H9YV72
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745518:HU722 RS23410
gene id: 2745518:HU722_RS23410
uniprot id: A0A8H9YME4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2745518:HU722 RS11015
gene id: 2745518:HU722_RS11015
uniprot id: A0A8H9YV98
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

2745518:HU722 RS15275
gene id: 2745518:HU722_RS15275
uniprot id: A0A8H9YWA3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2745518:HU722 RS21360
gene id: 2745518:HU722_RS21360
uniprot id: A0A8H9YKQ8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745518:HU722 RS20235
gene id: 2745518:HU722_RS20235
uniprot id: A0A8I0D0H3
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

2745518:HU722 RS24615
gene id: 2745518:HU722_RS24615
uniprot id: A0A8H9Z0J7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2745518:HU722 RS26300
gene id: 2745518:HU722_RS26300
uniprot id: A0A8H9YPY6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

2745518:HU722 RS19655
gene id: 2745518:HU722_RS19655
uniprot id: A0A8I0D2M3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS11610
gene id: 2745518:HU722_RS11610
uniprot id: A0A8H9Z2N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS14095
gene id: 2745518:HU722_RS14095
uniprot id: A0A8H9YYE6
names: Similarity
messages: Belongs to the EfeM/EfeO family.

2745518:HU722 RS16180
gene id: 2745518:HU722_RS16180
uniprot id: A0A8H9YWX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS08720
gene id: 2745518:HU722_RS08720
uniprot id: A0A8F4X0R3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS02550
gene id: 2745518:HU722_RS02550
uniprot id: A0A8H9YYV4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

2745518:HU722 RS18480
gene id: 2745518:HU722_RS18480
uniprot id: A0A8H9YSI8
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

2745518:HU722 RS16170
gene id: 2745518:HU722_RS16170
uniprot id: A0A8H9YY93
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

2745518:HU722 RS05940
gene id: 2745518:HU722_RS05940
uniprot id: A0A8H9YT35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

2745518:HU722 RS22425
gene id: 2745518:HU722_RS22425
uniprot id: A0A8I0CSS3
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

2745518:HU722 RS00645
gene id: 2745518:HU722_RS00645
uniprot id: A0A8H9YWS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS09745
gene id: 2745518:HU722_RS09745
uniprot id: A0A8I0CXQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

2745518:HU722 RS03600
gene id: 2745518:HU722_RS03600
uniprot id: A0A8H9YNE5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

2745518:HU722 RS21480
gene id: 2745518:HU722_RS21480
uniprot id: A0A8H9YKD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

2745518:HU722 RS02845
gene id: 2745518:HU722_RS02845
uniprot id: A0A8H9YP71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS07520
gene id: 2745518:HU722_RS07520
uniprot id: A0A8I0D1Z9
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

2745518:HU722 RS24700
gene id: 2745518:HU722_RS24700
uniprot id: A0A8H9Z0K3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS20505
gene id: 2745518:HU722_RS20505
uniprot id: A0A8H9YZX3
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

2745518:HU722 RS12245
gene id: 2745518:HU722_RS12245
uniprot id: A0A8H9Z3N3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS06425
gene id: 2745518:HU722_RS06425
uniprot id: A0A8H9YV57
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745518:HU722 RS02940
gene id: 2745518:HU722_RS02940
uniprot id: A0A8H9YMY4
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

2745518:HU722 RS09980
gene id: 2745518:HU722_RS09980
uniprot id: A0A8I0CX14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745518:HU722 RS21715
gene id: 2745518:HU722_RS21715
uniprot id: A0A8H9YLH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS09220
gene id: 2745518:HU722_RS09220
uniprot id: A0A8H9YRP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2745518:HU722 RS02395
gene id: 2745518:HU722_RS02395
uniprot id: A0A8H9YZ46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the agmatine deiminase family.
messages: Homodimer.
messages: Mediates the hydrolysis of agmatine into N-carbamoylputrescine in the arginine decarboxylase (ADC) pathway of putrescine biosynthesis, a basic polyamine.

2745518:HU722 RS24140
gene id: 2745518:HU722_RS24140
uniprot id: A0A8I0D1Y2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS26005
gene id: 2745518:HU722_RS26005
uniprot id: A0A8H9YQ21
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

2745518:HU722 RS27520
gene id: 2745518:HU722_RS27520
uniprot id: A0A8H9YS97
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2745518:HU722 RS11775
gene id: 2745518:HU722_RS11775
uniprot id: A0A8H9Z0J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

2745518:HU722 RS25635
gene id: 2745518:HU722_RS25635
uniprot id: A0A8H9YQL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

2745518:HU722 RS19720
gene id: 2745518:HU722_RS19720
uniprot id: A0A8I0D222
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS17240
gene id: 2745518:HU722_RS17240
uniprot id: A0A8H9YRE6
names: Similarity
messages: Belongs to the creatininase superfamily.

2745518:HU722 RS19090
gene id: 2745518:HU722_RS19090
uniprot id: A0A8H9Z0R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

2745518:HU722 RS27150
gene id: 2745518:HU722_RS27150
uniprot id: A0A8H9YRG1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745518:HU722 RS03520
gene id: 2745518:HU722_RS03520
uniprot id: A0A8F5ACW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

2745518:HU722 RS22535
gene id: 2745518:HU722_RS22535
uniprot id: A0A8H9YKG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.

2745518:HU722 RS05720
gene id: 2745518:HU722_RS05720
uniprot id: A0A8H9YUI6
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

2745518:HU722 RS02860
gene id: 2745518:HU722_RS02860
uniprot id: A0A8H9YN85
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

2745518:HU722 RS00205
gene id: 2745518:HU722_RS00205
uniprot id: A0A8I0D074
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

2745518:HU722 RS17565
gene id: 2745518:HU722_RS17565
uniprot id: A0A8H9YR20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS15280
gene id: 2745518:HU722_RS15280
uniprot id: A0A8H9YWZ4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2745518:HU722 RS06090
gene id: 2745518:HU722_RS06090
uniprot id: A0A8H9YT56
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2745518:HU722 RS02180
gene id: 2745518:HU722_RS02180
uniprot id: A0A8H9YXX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS17135
gene id: 2745518:HU722_RS17135
uniprot id: A0A8H9YPR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

2745518:HU722 RS16455
gene id: 2745518:HU722_RS16455
uniprot id: A0A8I0CYX1
names: Similarity
messages: Belongs to the class-C beta-lactamase family.

2745518:HU722 RS03165
gene id: 2745518:HU722_RS03165
uniprot id: A0A8H9YMW1
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

2745518:HU722 RS16565
gene id: 2745518:HU722_RS16565
uniprot id: A0A8H9YXI2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS27035
gene id: 2745518:HU722_RS27035
uniprot id: A0A8I0CWD0
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

2745518:HU722 RS17705
gene id: 2745518:HU722_RS17705
uniprot id: A0A8H9YRP2
names: Similarity
messages: Belongs to the UPF0434 family.

2745518:HU722 RS02060
gene id: 2745518:HU722_RS02060
uniprot id: A0A8I0CZG5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS18070
gene id: 2745518:HU722_RS18070
uniprot id: A0A8H9YQ66
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS06045
gene id: 2745518:HU722_RS06045
uniprot id: A0A8H9YTZ3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

2745518:HU722 RS06840
gene id: 2745518:HU722_RS06840
uniprot id: A0A8H9YW44
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS26275
gene id: 2745518:HU722_RS26275
uniprot id: A0A8I0CW47
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

2745518:HU722 RS22930
gene id: 2745518:HU722_RS22930
uniprot id: A0A8H9YKT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

2745518:HU722 RS17790
gene id: 2745518:HU722_RS17790
uniprot id: A0A8H9YRQ0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

2745518:HU722 RS03420
gene id: 2745518:HU722_RS03420
uniprot id: A0A8I0CV31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

2745518:HU722 RS02810
gene id: 2745518:HU722_RS02810
uniprot id: A0A8I0CVL3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745518:HU722 RS26330
gene id: 2745518:HU722_RS26330
uniprot id: A0A8H9YQQ7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

2745518:HU722 RS26495
gene id: 2745518:HU722_RS26495
uniprot id: A0A8I0CW65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2745518:HU722 RS27450
gene id: 2745518:HU722_RS27450
uniprot id: A0A8H9YRA5
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS10915
gene id: 2745518:HU722_RS10915
uniprot id: A0A8I0CY82
names: Function
names: Similarity
messages: Belongs to the PqqA family.
messages: Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.

2745518:HU722 RS22550
gene id: 2745518:HU722_RS22550
uniprot id: A0A8H9YMF2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

2745518:HU722 RS21075
gene id: 2745518:HU722_RS21075
uniprot id: A0A8I0CTI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

2745518:HU722 RS04840
gene id: 2745518:HU722_RS04840
uniprot id: A0A8I0D2D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

2745518:HU722 RS05400
gene id: 2745518:HU722_RS05400
uniprot id: A0A8H9YSW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS01325
gene id: 2745518:HU722_RS01325
uniprot id: A0A8H9YVX5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS00940
gene id: 2745518:HU722_RS00940
uniprot id: A0A8H9YVK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2745518:HU722 RS23135
gene id: 2745518:HU722_RS23135
uniprot id: A0A8I0CU42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS23245
gene id: 2745518:HU722_RS23245
uniprot id: A0A8H9YM69
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

2745518:HU722 RS10880
gene id: 2745518:HU722_RS10880
uniprot id: A0A8H9YU89
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS21690
gene id: 2745518:HU722_RS21690
uniprot id: A0A8I0CUQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

2745518:HU722 RS19000
gene id: 2745518:HU722_RS19000
uniprot id: A0A8I0D0R6
names: Similarity
messages: Belongs to the DSD1 family.

2745518:HU722 RS08070
gene id: 2745518:HU722_RS08070
uniprot id: A0A8H9YY40
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745518:HU722 RS05975
gene id: 2745518:HU722_RS05975
uniprot id: A0A8H9YV07
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

2745518:HU722 RS14245
gene id: 2745518:HU722_RS14245
uniprot id: A0A8H9YY28
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2745518:HU722 RS02850
gene id: 2745518:HU722_RS02850
uniprot id: A0A8H9YPD4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS18145
gene id: 2745518:HU722_RS18145
uniprot id: A0A8H9YQ81
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS10550
gene id: 2745518:HU722_RS10550
uniprot id: A0A8H9YVY2
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS13135
gene id: 2745518:HU722_RS13135
uniprot id: A0A8H9YZD6
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.
messages: Belongs to the TPP enzyme family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Cell membrane
messages: Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.

2745518:HU722 RS26620
gene id: 2745518:HU722_RS26620
uniprot id: A0A8H9YRA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

2745518:HU722 RS26450
gene id: 2745518:HU722_RS26450
uniprot id: A0A8H9YQ00
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

2745518:HU722 RS26040
gene id: 2745518:HU722_RS26040
uniprot id: A0A8I0CVH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

2745518:HU722 RS07535
gene id: 2745518:HU722_RS07535
uniprot id: A0A8I0D2K7
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

2745518:HU722 RS01200
gene id: 2745518:HU722_RS01200
uniprot id: A0A8H9YUF9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS23015
gene id: 2745518:HU722_RS23015
uniprot id: A0A8H9YLC7
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS27040
gene id: 2745518:HU722_RS27040
uniprot id: A0A8H9YTF4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS06685
gene id: 2745518:HU722_RS06685
uniprot id: A0A8H9YW63
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

2745518:HU722 RS26810
gene id: 2745518:HU722_RS26810
uniprot id: A0A8H9YTH9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS20220
gene id: 2745518:HU722_RS20220
uniprot id: A0A8H9Z0A8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

2745518:HU722 RS13845
gene id: 2745518:HU722_RS13845
uniprot id: A0A8I0D2V5
names: Similarity
messages: Belongs to the pirin family.

2745518:HU722 RS05635
gene id: 2745518:HU722_RS05635
uniprot id: A0A8H9YT95
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

2745518:HU722 RS02835
gene id: 2745518:HU722_RS02835
uniprot id: A0A8H9YNP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2745518:HU722 RS20180
gene id: 2745518:HU722_RS20180
uniprot id: A0A8H9YY95
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS09165
gene id: 2745518:HU722_RS09165
uniprot id: A0A8I0CX70
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

2745518:HU722 RS18525
gene id: 2745518:HU722_RS18525
uniprot id: A0A8H9Z3I7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS11925
gene id: 2745518:HU722_RS11925
uniprot id: A0A8H9Z0L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm

2745518:HU722 RS23005
gene id: 2745518:HU722_RS23005
uniprot id: A0A8H9YJS0
names: Similarity
messages: Belongs to the GST superfamily.

2745518:HU722 RS23220
gene id: 2745518:HU722_RS23220
uniprot id: A0A8I0CUZ7
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

2745518:HU722 RS05455
gene id: 2745518:HU722_RS05455
uniprot id: A0A8I0CY61
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

2745518:HU722 RS27315
gene id: 2745518:HU722_RS27315
uniprot id: A0A8I0CXI9
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

2745518:HU722 RS15915
gene id: 2745518:HU722_RS15915
uniprot id: A0A8H9YYM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

2745518:HU722 RS01420
gene id: 2745518:HU722_RS01420
uniprot id: A0A8H9YUI7
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

2745518:HU722 RS26415
gene id: 2745518:HU722_RS26415
uniprot id: A0A8I0CVK2
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS20455
gene id: 2745518:HU722_RS20455
uniprot id: A0A8I0D0H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS07550
gene id: 2745518:HU722_RS07550
uniprot id: A0A8F4X1H4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

2745518:HU722 RS20945
gene id: 2745518:HU722_RS20945
uniprot id: A0A8H9YI72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

2745518:HU722 RS27915
gene id: 2745518:HU722_RS27915
uniprot id: A0A8H9YQV2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

2745518:HU722 RS15805
gene id: 2745518:HU722_RS15805
uniprot id: A0A8H9YWP4
names: Similarity
messages: Belongs to the DapA family.

2745518:HU722 RS11635
gene id: 2745518:HU722_RS11635
uniprot id: A0A8I0D2S5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2745518:HU722 RS13700
gene id: 2745518:HU722_RS13700
uniprot id: A0A8H9YYS8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS12400
gene id: 2745518:HU722_RS12400
uniprot id: A0A8H9Z3Q3
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

2745518:HU722 RS01300
gene id: 2745518:HU722_RS01300
uniprot id: A0A8I0CYJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

2745518:HU722 RS08690
gene id: 2745518:HU722_RS08690
uniprot id: A0A8H9YZC8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

2745518:HU722 RS23320
gene id: 2745518:HU722_RS23320
uniprot id: A0A8H9YM76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

2745518:HU722 RS24230
gene id: 2745518:HU722_RS24230
uniprot id: A0A8I0D0R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

2745518:HU722 RS16875
gene id: 2745518:HU722_RS16875
uniprot id: A0A8I0D2Q6
names: Similarity
messages: Belongs to the DSD1 family.

2745518:HU722 RS22805
gene id: 2745518:HU722_RS22805
uniprot id: A0A8H9YMT6
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS25640
gene id: 2745518:HU722_RS25640
uniprot id: A0A8H9YR03
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

2745518:HU722 RS26515
gene id: 2745518:HU722_RS26515
uniprot id: A0A8H9YPM0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2745518:HU722 RS04915
gene id: 2745518:HU722_RS04915
uniprot id: A0A8I0D2D5
names: Similarity
messages: Belongs to the CFA/CMAS family.

2745518:HU722 RS25745
gene id: 2745518:HU722_RS25745
uniprot id: A0A8I0CW19
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745518:HU722 RS08860
gene id: 2745518:HU722_RS08860
uniprot id: A0A8H9Z4P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

2745518:HU722 RS10235
gene id: 2745518:HU722_RS10235
uniprot id: A0A8H9Z413
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS23485
gene id: 2745518:HU722_RS23485
uniprot id: A0A8H9YMF8
names: Similarity
messages: Belongs to the SlyX family.

2745518:HU722 RS20500
gene id: 2745518:HU722_RS20500
uniprot id: A0A8H9Z024
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

2745518:HU722 RS03580
gene id: 2745518:HU722_RS03580
uniprot id: A0A8I0CV00
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

2745518:HU722 RS24750
gene id: 2745518:HU722_RS24750
uniprot id: A0A8I0D1K9
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

2745518:HU722 RS28595
gene id: 2745518:HU722_RS28595
uniprot id: A0A8I0D0R1
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

2745518:HU722 RS11405
gene id: 2745518:HU722_RS11405
uniprot id: A0A8H9YUN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS21445
gene id: 2745518:HU722_RS21445
uniprot id: A0A8I0CTM9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

2745518:HU722 RS10830
gene id: 2745518:HU722_RS10830
uniprot id: A0A8I0CYQ2
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS03160
gene id: 2745518:HU722_RS03160
uniprot id: A0A8H9YN47
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745518:HU722 RS24045
gene id: 2745518:HU722_RS24045
uniprot id: A0A8H9Z094
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

2745518:HU722 RS12855
gene id: 2745518:HU722_RS12855
uniprot id: A0A8I0D1A4
names: Similarity
messages: Belongs to the TPP enzyme family.

2745518:HU722 RS27525
gene id: 2745518:HU722_RS27525
uniprot id: A0A8H9YRL6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

2745518:HU722 RS05710
gene id: 2745518:HU722_RS05710
uniprot id: A0A8H9YTA2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

2745518:HU722 RS20510
gene id: 2745518:HU722_RS20510
uniprot id: A0A8H9Z0G8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS26895
gene id: 2745518:HU722_RS26895
uniprot id: A0A8F5ACH0
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

2745518:HU722 RS03495
gene id: 2745518:HU722_RS03495
uniprot id: A0A8I0CV08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

2745518:HU722 RS06585
gene id: 2745518:HU722_RS06585
uniprot id: A0A8H9YY74
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS08390
gene id: 2745518:HU722_RS08390
uniprot id: A0A8I0CZA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

2745518:HU722 RS06385
gene id: 2745518:HU722_RS06385
uniprot id: A0A8H9YT09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS14625
gene id: 2745518:HU722_RS14625
uniprot id: A0A8H9Z193
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745518:HU722 RS26600
gene id: 2745518:HU722_RS26600
uniprot id: A0A8H9YQ14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

2745518:HU722 RS19520
gene id: 2745518:HU722_RS19520
uniprot id: A0A8H9Z3Y8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2745518:HU722 RS05170
gene id: 2745518:HU722_RS05170
uniprot id: A0A8H9Z382
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

2745518:HU722 RS25085
gene id: 2745518:HU722_RS25085
uniprot id: A0A8H9YP50
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

2745518:HU722 RS23530
gene id: 2745518:HU722_RS23530
uniprot id: A0A8H9YKG3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

2745518:HU722 RS23475
gene id: 2745518:HU722_RS23475
uniprot id: A0A8H9YM96
names: Similarity
messages: Belongs to the Dps family.

2745518:HU722 RS28205
gene id: 2745518:HU722_RS28205
uniprot id: A0A8I0D105
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

2745518:HU722 RS11875
gene id: 2745518:HU722_RS11875
uniprot id: A0A8H9Z1P5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

2745518:HU722 RS00080
gene id: 2745518:HU722_RS00080
uniprot id: A0A8H9YXS6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2745518:HU722 RS17595
gene id: 2745518:HU722_RS17595
uniprot id: A0A8I0CWZ6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745518:HU722 RS21320
gene id: 2745518:HU722_RS21320
uniprot id: A0A8H9YIH2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS18460
gene id: 2745518:HU722_RS18460
uniprot id: A0A8H9YRK6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS00480
gene id: 2745518:HU722_RS00480
uniprot id: A0A8H9YZZ6
names: Similarity
messages: Belongs to the asparaginase 1 family.

2745518:HU722 RS22325
gene id: 2745518:HU722_RS22325
uniprot id: A0A8H9YMB8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2745518:HU722 RS07525
gene id: 2745518:HU722_RS07525
uniprot id: A0A8I0D210
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS26855
gene id: 2745518:HU722_RS26855
uniprot id: A0A8H9YR94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

2745518:HU722 RS17340
gene id: 2745518:HU722_RS17340
uniprot id: A0A8I0CWA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS11350
gene id: 2745518:HU722_RS11350
uniprot id: A0A8I0CYQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

2745518:HU722 RS27265
gene id: 2745518:HU722_RS27265
uniprot id: A0A8H9YTC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
messages: Homotetramer.

2745518:HU722 RS00405
gene id: 2745518:HU722_RS00405
uniprot id: A0A8H9YZC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

2745518:HU722 RS15385
gene id: 2745518:HU722_RS15385
uniprot id: A0A8I0CYY2
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS03525
gene id: 2745518:HU722_RS03525
uniprot id: A0A8H9YNX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

2745518:HU722 RS16715
gene id: 2745518:HU722_RS16715
uniprot id: A0A8H9Z1S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS21310
gene id: 2745518:HU722_RS21310
uniprot id: A0A8I0CU98
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

2745518:HU722 RS13940
gene id: 2745518:HU722_RS13940
uniprot id: A0A8H9YXZ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

2745518:HU722 RS27950
gene id: 2745518:HU722_RS27950
uniprot id: A0A8H9YRX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

2745518:HU722 RS28505
gene id: 2745518:HU722_RS28505
uniprot id: A0A8I0D1K8
names: Similarity
messages: Belongs to the GppA/Ppx family.

2745518:HU722 RS15360
gene id: 2745518:HU722_RS15360
uniprot id: A0A8H9YWT9
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

2745518:HU722 RS25170
gene id: 2745518:HU722_RS25170
uniprot id: A0A8H9YPQ8
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

2745518:HU722 RS13160
gene id: 2745518:HU722_RS13160
uniprot id: A0A8I0D0Z6
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

2745518:HU722 RS26480
gene id: 2745518:HU722_RS26480
uniprot id: A0A8H9YQS5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2745518:HU722 RS04035
gene id: 2745518:HU722_RS04035
uniprot id: A0A8I0CUB8
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS26525
gene id: 2745518:HU722_RS26525
uniprot id: A0A8H9YQ10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

2745518:HU722 RS05110
gene id: 2745518:HU722_RS05110
uniprot id: A0A8I0D3B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

2745518:HU722 RS05045
gene id: 2745518:HU722_RS05045
uniprot id: A0A8H9Z2X0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

2745518:HU722 RS02995
gene id: 2745518:HU722_RS02995
uniprot id: A0A8H9YP40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS07100
gene id: 2745518:HU722_RS07100
uniprot id: A0A8H9YXV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

2745518:HU722 RS28620
gene id: 2745518:HU722_RS28620
uniprot id: A0A8H9YYM1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

2745518:HU722 RS24650
gene id: 2745518:HU722_RS24650
uniprot id: A0A8H9Z2P1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745518:HU722 RS15265
gene id: 2745518:HU722_RS15265
uniprot id: A0A8H9YVE5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2745518:HU722 RS22305
gene id: 2745518:HU722_RS22305
uniprot id: A0A8H9YJ38
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

2745518:HU722 RS19140
gene id: 2745518:HU722_RS19140
uniprot id: A0A8I0D1B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS01395
gene id: 2745518:HU722_RS01395
uniprot id: A0A8H9YWI3
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

2745518:HU722 RS05650
gene id: 2745518:HU722_RS05650
uniprot id: A0A8H9YUC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.

2745518:HU722 RS02905
gene id: 2745518:HU722_RS02905
uniprot id: A0A8H9YPW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

2745518:HU722 RS17600
gene id: 2745518:HU722_RS17600
uniprot id: A0A8H9YPW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS23230
gene id: 2745518:HU722_RS23230
uniprot id: A0A8H9YJY3
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS06790
gene id: 2745518:HU722_RS06790
uniprot id: A0A8I0CZC1
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS05950
gene id: 2745518:HU722_RS05950
uniprot id: A0A8H9YU11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

2745518:HU722 RS24620
gene id: 2745518:HU722_RS24620
uniprot id: A0A8H9Z0J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2745518:HU722 RS04090
gene id: 2745518:HU722_RS04090
uniprot id: A0A8F4WZ28
names: Similarity
messages: Belongs to the peptidase A24 family.

2745518:HU722 RS20970
gene id: 2745518:HU722_RS20970
uniprot id: A0A8H9YLR1
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

2745518:HU722 RS03170
gene id: 2745518:HU722_RS03170
uniprot id: A0A8H9YMH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS06365
gene id: 2745518:HU722_RS06365
uniprot id: A0A8I0CXV2
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS22445
gene id: 2745518:HU722_RS22445
uniprot id: A0A8I0CUV1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2745518:HU722 RS28510
gene id: 2745518:HU722_RS28510
uniprot id: A0A8I0D0Y8
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

2745518:HU722 RS17310
gene id: 2745518:HU722_RS17310
uniprot id: A0A8H9YRK4
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

2745518:HU722 RS13980
gene id: 2745518:HU722_RS13980
uniprot id: A0A8I0CZM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

2745518:HU722 RS27540
gene id: 2745518:HU722_RS27540
uniprot id: A0A8H9YR04
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS08305
gene id: 2745518:HU722_RS08305
uniprot id: A0A8H9YZ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

2745518:HU722 RS24730
gene id: 2745518:HU722_RS24730
uniprot id: A0A8H9Z1F1
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

2745518:HU722 RS08200
gene id: 2745518:HU722_RS08200
uniprot id: A0A8H9YXH6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745518:HU722 RS04210
gene id: 2745518:HU722_RS04210
uniprot id: A0A8H9YNW2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

2745518:HU722 RS28260
gene id: 2745518:HU722_RS28260
uniprot id: A0A8I0D282
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

2745518:HU722 RS26580
gene id: 2745518:HU722_RS26580
uniprot id: A0A8I0CWP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2745518:HU722 RS24060
gene id: 2745518:HU722_RS24060
uniprot id: A0A8I0D1Y6
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS21025
gene id: 2745518:HU722_RS21025
uniprot id: A0A8H9YI87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

2745518:HU722 RS02725
gene id: 2745518:HU722_RS02725
uniprot id: A0A8H9YMP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS09705
gene id: 2745518:HU722_RS09705
uniprot id: A0A8F4X127
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

2745518:HU722 RS18930
gene id: 2745518:HU722_RS18930
uniprot id: A0A8I0D0N4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2745518:HU722 RS26585
gene id: 2745518:HU722_RS26585
uniprot id: A0A8I0CWU9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2745518:HU722 RS28335
gene id: 2745518:HU722_RS28335
uniprot id: A0A8I0D278
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2745518:HU722 RS28285
gene id: 2745518:HU722_RS28285
uniprot id: A0A8H9Z2P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm

2745518:HU722 RS11655
gene id: 2745518:HU722_RS11655
uniprot id: A0A8H9Z1V8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2745518:HU722 RS15270
gene id: 2745518:HU722_RS15270
uniprot id: A0A8H9YVM0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745518:HU722 RS27995
gene id: 2745518:HU722_RS27995
uniprot id: A0A8I0CXE0
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

2745518:HU722 RS02975
gene id: 2745518:HU722_RS02975
uniprot id: A0A8I0CUK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

2745518:HU722 RS28710
gene id: 2745518:HU722_RS28710
uniprot id: A0A8H9YZS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS03205
gene id: 2745518:HU722_RS03205
uniprot id: A0A8H9YPU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

2745518:HU722 RS27770
gene id: 2745518:HU722_RS27770
uniprot id: A0A8I0CXF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

2745518:HU722 RS16075
gene id: 2745518:HU722_RS16075
uniprot id: A0A8H9YYQ6
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS28445
gene id: 2745518:HU722_RS28445
uniprot id: A0A8H9Z1H5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

2745518:HU722 RS02920
gene id: 2745518:HU722_RS02920
uniprot id: A0A8H9YP55
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

2745518:HU722 RS02805
gene id: 2745518:HU722_RS02805
uniprot id: A0A8I0CVW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS09940
gene id: 2745518:HU722_RS09940
uniprot id: A0A8H9YT58
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

2745518:HU722 RS27530
gene id: 2745518:HU722_RS27530
uniprot id: A0A8H9YR98
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

2745518:HU722 RS03530
gene id: 2745518:HU722_RS03530
uniprot id: A0A8H9YP47
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

2745518:HU722 RS11295
gene id: 2745518:HU722_RS11295
uniprot id: A0A8I0CXI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

2745518:HU722 RS18670
gene id: 2745518:HU722_RS18670
uniprot id: A0A8H9YZD3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS15210
gene id: 2745518:HU722_RS15210
uniprot id: A0A8H9YWR3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homohexamer, formed by a dimer of trimers.
messages: In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: In the N-terminal section; belongs to the Fmt family. UDP-L-Ara4N formyltransferase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS00355
gene id: 2745518:HU722_RS00355
uniprot id: A0A8I0D085
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

2745518:HU722 RS19710
gene id: 2745518:HU722_RS19710
uniprot id: A0A8H9Z3J1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS18245
gene id: 2745518:HU722_RS18245
uniprot id: A0A8H9YRT1
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS10520
gene id: 2745518:HU722_RS10520
uniprot id: A0A8I0CYW1
names: Similarity
messages: Belongs to the AHA1 family.

2745518:HU722 RS07805
gene id: 2745518:HU722_RS07805
uniprot id: A0A8I0D1U6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS27595
gene id: 2745518:HU722_RS27595
uniprot id: A0A8H9YS89
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

2745518:HU722 RS16155
gene id: 2745518:HU722_RS16155
uniprot id: A0A8H9YXM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homodimer.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

2745518:HU722 RS10955
gene id: 2745518:HU722_RS10955
uniprot id: A0A8H9YU79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

2745518:HU722 RS09315
gene id: 2745518:HU722_RS09315
uniprot id: A0A8I0CWK2
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS08660
gene id: 2745518:HU722_RS08660
uniprot id: A0A8H9YXN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

2745518:HU722 RS28220
gene id: 2745518:HU722_RS28220
uniprot id: A0A8H9Z2V9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS07130
gene id: 2745518:HU722_RS07130
uniprot id: A0A8H9YW88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS26745
gene id: 2745518:HU722_RS26745
uniprot id: A0A8H9YTJ4
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

2745518:HU722 RS17880
gene id: 2745518:HU722_RS17880
uniprot id: A0A8H9YR62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

2745518:HU722 RS25570
gene id: 2745518:HU722_RS25570
uniprot id: A0A8H9YQY1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

2745518:HU722 RS17950
gene id: 2745518:HU722_RS17950
uniprot id: A0A8H9YSD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS19690
gene id: 2745518:HU722_RS19690
uniprot id: A0A8H9Z386
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

2745518:HU722 RS28075
gene id: 2745518:HU722_RS28075
uniprot id: A0A8I0D306
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

2745518:HU722 RS23400
gene id: 2745518:HU722_RS23400
uniprot id: A0A8H9YM86
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS02985
gene id: 2745518:HU722_RS02985
uniprot id: A0A8H9YNM9
names: Similarity
messages: Belongs to the glutamate synthase family.

2745518:HU722 RS05365
gene id: 2745518:HU722_RS05365
uniprot id: A0A8H9Z1N0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

2745518:HU722 RS21120
gene id: 2745518:HU722_RS21120
uniprot id: A0A8H9YLU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

2745518:HU722 RS07380
gene id: 2745518:HU722_RS07380
uniprot id: A0A8I0CZN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS17305
gene id: 2745518:HU722_RS17305
uniprot id: A0A8H9YR51
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

2745518:HU722 RS19715
gene id: 2745518:HU722_RS19715
uniprot id: A0A8I0D1D9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS19530
gene id: 2745518:HU722_RS19530
uniprot id: A0A8H9Z368
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

2745518:HU722 RS09280
gene id: 2745518:HU722_RS09280
uniprot id: A0A8H9YS98
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

2745518:HU722 RS01350
gene id: 2745518:HU722_RS01350
uniprot id: A0A8H9YUD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

2745518:HU722 RS13230
gene id: 2745518:HU722_RS13230
uniprot id: A0A8I0D0K5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS02125
gene id: 2745518:HU722_RS02125
uniprot id: A0A8I0D0P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS01680
gene id: 2745518:HU722_RS01680
uniprot id: A0A8H9Z102
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2745518:HU722 RS20010
gene id: 2745518:HU722_RS20010
uniprot id: A0A8I0D104
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS03970
gene id: 2745518:HU722_RS03970
uniprot id: A0A8H9YN92
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

2745518:HU722 RS02145
gene id: 2745518:HU722_RS02145
uniprot id: A0A8I0CZG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS02645
gene id: 2745518:HU722_RS02645
uniprot id: A0A8H9YMQ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

2745518:HU722 RS27830
gene id: 2745518:HU722_RS27830
uniprot id: A0A8H9YR65
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

2745518:HU722 RS10125
gene id: 2745518:HU722_RS10125
uniprot id: A0A8I0CXI0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS22215
gene id: 2745518:HU722_RS22215
uniprot id: A0A8I0CUH7
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

2745518:HU722 RS04990
gene id: 2745518:HU722_RS04990
uniprot id: A0A8I0D2C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

2745518:HU722 RS12545
gene id: 2745518:HU722_RS12545
uniprot id: A0A8H9Z486
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS27885
gene id: 2745518:HU722_RS27885
uniprot id: A0A8H9YSF7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

2745518:HU722 RS13595
gene id: 2745518:HU722_RS13595
uniprot id: A0A8H9Z0L5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2745518:HU722 RS21105
gene id: 2745518:HU722_RS21105
uniprot id: A0A8H9YIX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745518:HU722 RS16530
gene id: 2745518:HU722_RS16530
uniprot id: A0A8F5AB63
names: Similarity
messages: Belongs to the autoinducer synthase family.

2745518:HU722 RS12530
gene id: 2745518:HU722_RS12530
uniprot id: A0A8H9Z307
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

2745518:HU722 RS16700
gene id: 2745518:HU722_RS16700
uniprot id: A0A8H9Z277
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745518:HU722 RS09365
gene id: 2745518:HU722_RS09365
uniprot id: A0A8H9YRM3
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

2745518:HU722 RS26310
gene id: 2745518:HU722_RS26310
uniprot id: A0A8H9YQV8
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

2745518:HU722 RS09030
gene id: 2745518:HU722_RS09030
uniprot id: A0A8H9YSU1
names: Similarity
messages: Belongs to the MQO family.

2745518:HU722 RS01675
gene id: 2745518:HU722_RS01675
uniprot id: A0A8H9Z0Y9
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS10005
gene id: 2745518:HU722_RS10005
uniprot id: A0A8H9YTL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

2745518:HU722 RS18595
gene id: 2745518:HU722_RS18595
uniprot id: A0A8H9Z2T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

2745518:HU722 RS04175
gene id: 2745518:HU722_RS04175
uniprot id: A0A8I0CUW1
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

2745518:HU722 RS25915
gene id: 2745518:HU722_RS25915
uniprot id: A0A8H9YPF5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS14640
gene id: 2745518:HU722_RS14640
uniprot id: A0A8F5AAV2
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

2745518:HU722 RS00705
gene id: 2745518:HU722_RS00705
uniprot id: A0A8I0CY05
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflK subfamily.

2745518:HU722 RS27000
gene id: 2745518:HU722_RS27000
uniprot id: A0A8H9YRI9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

2745518:HU722 RS01410
gene id: 2745518:HU722_RS01410
uniprot id: A0A8H9YVG0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

2745518:HU722 RS05705
gene id: 2745518:HU722_RS05705
uniprot id: A0A8H9YT06
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

2745518:HU722 RS05960
gene id: 2745518:HU722_RS05960
uniprot id: A0A8H9YUG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2745518:HU722 RS19980
gene id: 2745518:HU722_RS19980
uniprot id: A0A8H9YZ59
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS27890
gene id: 2745518:HU722_RS27890
uniprot id: A0A8H9YSN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

2745518:HU722 RS18360
gene id: 2745518:HU722_RS18360
uniprot id: A0A8I0CX41
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS05010
gene id: 2745518:HU722_RS05010
uniprot id: A0A8H9Z4V5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

2745518:HU722 RS05670
gene id: 2745518:HU722_RS05670
uniprot id: A0A8I0CX43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

2745518:HU722 RS25765
gene id: 2745518:HU722_RS25765
uniprot id: A0A8H9YPE0
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.

2745518:HU722 RS12275
gene id: 2745518:HU722_RS12275
uniprot id: A0A8H9Z240
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

2745518:HU722 RS21785
gene id: 2745518:HU722_RS21785
uniprot id: A0A8H9YKM1
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

2745518:HU722 RS02795
gene id: 2745518:HU722_RS02795
uniprot id: A0A8H9YMN0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2745518:HU722 RS04060
gene id: 2745518:HU722_RS04060
uniprot id: A0A8H9YNX9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS16745
gene id: 2745518:HU722_RS16745
uniprot id: A0A8H9Z3S4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2745518:HU722 RS14005
gene id: 2745518:HU722_RS14005
uniprot id: A0A8H9YY16
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

2745518:HU722 RS10680
gene id: 2745518:HU722_RS10680
uniprot id: A0A8I0CYR3
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS01575
gene id: 2745518:HU722_RS01575
uniprot id: A0A8H9Z395
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS11300
gene id: 2745518:HU722_RS11300
uniprot id: A0A8H9YVN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS03595
gene id: 2745518:HU722_RS03595
uniprot id: A0A8H9YPP1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

2745518:HU722 RS05605
gene id: 2745518:HU722_RS05605
uniprot id: A0A8I0CXQ4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

2745518:HU722 RS17700
gene id: 2745518:HU722_RS17700
uniprot id: A0A8H9YR97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

2745518:HU722 RS26665
gene id: 2745518:HU722_RS26665
uniprot id: A0A8H9YPP3
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

2745518:HU722 RS02185
gene id: 2745518:HU722_RS02185
uniprot id: A0A8H9YXK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS05520
gene id: 2745518:HU722_RS05520
uniprot id: A0A8I0CX33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

2745518:HU722 RS17910
gene id: 2745518:HU722_RS17910
uniprot id: A0A8I0CX13
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

2745518:HU722 RS08215
gene id: 2745518:HU722_RS08215
uniprot id: A0A8H9YYN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

2745518:HU722 RS26320
gene id: 2745518:HU722_RS26320
uniprot id: A0A8H9YR71
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

2745518:HU722 RS11285
gene id: 2745518:HU722_RS11285
uniprot id: A0A8F5AF93
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2745518:HU722 RS02970
gene id: 2745518:HU722_RS02970
uniprot id: A0A8I0CV60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

2745518:HU722 RS09515
gene id: 2745518:HU722_RS09515
uniprot id: A0A8H9YRK0
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

2745518:HU722 RS23815
gene id: 2745518:HU722_RS23815
uniprot id: A0A8I0CU97
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS05440
gene id: 2745518:HU722_RS05440
uniprot id: A0A8I0CX28
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2745518:HU722 RS18020
gene id: 2745518:HU722_RS18020
uniprot id: A0A8H9YRP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745518:HU722 RS22510
gene id: 2745518:HU722_RS22510
uniprot id: A0A8I0CTX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

2745518:HU722 RS25650
gene id: 2745518:HU722_RS25650
uniprot id: A0A8H9YRJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

2745518:HU722 RS17090
gene id: 2745518:HU722_RS17090
uniprot id: A0A8H9YS08
names: Similarity
messages: Belongs to the SCO1/2 family.

2745518:HU722 RS23920
gene id: 2745518:HU722_RS23920
uniprot id: A0A8I0D1F1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

2745518:HU722 RS06445
gene id: 2745518:HU722_RS06445
uniprot id: A0A8I0CYD0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745518:HU722 RS18760
gene id: 2745518:HU722_RS18760
uniprot id: A0A8H9YYZ8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2745518:HU722 RS23615
gene id: 2745518:HU722_RS23615
uniprot id: A0A8H9YLA2
names: Similarity
messages: Belongs to the pyruvate kinase family.

2745518:HU722 RS26750
gene id: 2745518:HU722_RS26750
uniprot id: A0A8H9YSW1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

2745518:HU722 RS24165
gene id: 2745518:HU722_RS24165
uniprot id: A0A8H9Z131
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

2745518:HU722 RS28340
gene id: 2745518:HU722_RS28340
uniprot id: A0A8I0D276
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2745518:HU722 RS27790
gene id: 2745518:HU722_RS27790
uniprot id: A0A8I0CW93
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

2745518:HU722 RS23940
gene id: 2745518:HU722_RS23940
uniprot id: A0A8H9Z2F2
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS21210
gene id: 2745518:HU722_RS21210
uniprot id: A0A8H9YKI9
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

2745518:HU722 RS24575
gene id: 2745518:HU722_RS24575
uniprot id: A0A8H9Z2M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

2745518:HU722 RS26565
gene id: 2745518:HU722_RS26565
uniprot id: A0A8I0CVL1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2745518:HU722 RS22910
gene id: 2745518:HU722_RS22910
uniprot id: A0A8I0CUM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

2745518:HU722 RS09520
gene id: 2745518:HU722_RS09520
uniprot id: A0A8I0CXR7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS16095
gene id: 2745518:HU722_RS16095
uniprot id: A0A8H9YYA6
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

2745518:HU722 RS05540
gene id: 2745518:HU722_RS05540
uniprot id: A0A8I0CYB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

2745518:HU722 RS01975
gene id: 2745518:HU722_RS01975
uniprot id: A0A8I0D058
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS27505
gene id: 2745518:HU722_RS27505
uniprot id: A0A8H9YT88
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

2745518:HU722 RS25700
gene id: 2745518:HU722_RS25700
uniprot id: A0A8H9YPQ6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

2745518:HU722 RS15675
gene id: 2745518:HU722_RS15675
uniprot id: A0A8H9YXE0
names: Similarity
messages: Belongs to the DinB family.

2745518:HU722 RS25185
gene id: 2745518:HU722_RS25185
uniprot id: A0A8H9YQT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

2745518:HU722 RS12620
gene id: 2745518:HU722_RS12620
uniprot id: A0A8I0D1V3
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

2745518:HU722 RS16545
gene id: 2745518:HU722_RS16545
uniprot id: A0A8H9YXH3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

2745518:HU722 RS17030
gene id: 2745518:HU722_RS17030
uniprot id: A0A8I0CVM5
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

2745518:HU722 RS21055
gene id: 2745518:HU722_RS21055
uniprot id: A0A8H9YM75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS16730
gene id: 2745518:HU722_RS16730
uniprot id: A0A8I0D275
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS01720
gene id: 2745518:HU722_RS01720
uniprot id: A0A8F5ACY8
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS06555
gene id: 2745518:HU722_RS06555
uniprot id: A0A8H9YUV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

2745518:HU722 RS11355
gene id: 2745518:HU722_RS11355
uniprot id: A0A8I0CYL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

2745518:HU722 RS06370
gene id: 2745518:HU722_RS06370
uniprot id: A0A8I0CYC4
names: Similarity
messages: Belongs to the UPF0162 family.

2745518:HU722 RS11900
gene id: 2745518:HU722_RS11900
uniprot id: A0A8I0D1S3
names: Similarity
messages: Belongs to the IlvD/Edd family.

2745518:HU722 RS19555
gene id: 2745518:HU722_RS19555
uniprot id: A0A8H9Z408
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

2745518:HU722 RS06520
gene id: 2745518:HU722_RS06520
uniprot id: A0A8I0CYD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

2745518:HU722 RS19435
gene id: 2745518:HU722_RS19435
uniprot id: A0A8H9Z478
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS20550
gene id: 2745518:HU722_RS20550
uniprot id: A0A8H9YYJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

2745518:HU722 RS25660
gene id: 2745518:HU722_RS25660
uniprot id: A0A8H9YRH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

2745518:HU722 RS01775
gene id: 2745518:HU722_RS01775
uniprot id: A0A8I0D1R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS26610
gene id: 2745518:HU722_RS26610
uniprot id: A0A8H9YR00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2745518:HU722 RS27365
gene id: 2745518:HU722_RS27365
uniprot id: A0A8H9YSC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. L-carnitine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3-dehydrocarnitine.
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS04120
gene id: 2745518:HU722_RS04120
uniprot id: A0A8H9YN71
names: Similarity
messages: Belongs to the GSP E family.

2745518:HU722 RS03825
gene id: 2745518:HU722_RS03825
uniprot id: A0A8H9YPG4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

2745518:HU722 RS07155
gene id: 2745518:HU722_RS07155
uniprot id: A0A8I0CZP7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS06525
gene id: 2745518:HU722_RS06525
uniprot id: A0A8I0CYH6
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

2745518:HU722 RS04780
gene id: 2745518:HU722_RS04780
uniprot id: A0A8I0D158
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS00950
gene id: 2745518:HU722_RS00950
uniprot id: A0A8H9YW29
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS00965
gene id: 2745518:HU722_RS00965
uniprot id: A0A8F4WZ73
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

2745518:HU722 RS00570
gene id: 2745518:HU722_RS00570
uniprot id: A0A8H9YWT1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

2745518:HU722 RS03440
gene id: 2745518:HU722_RS03440
uniprot id: A0A8H9YPL3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

2745518:HU722 RS28275
gene id: 2745518:HU722_RS28275
uniprot id: A0A8I0D1M1
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

2745518:HU722 RS27615
gene id: 2745518:HU722_RS27615
uniprot id: A0A8H9YQZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

2745518:HU722 RS16535
gene id: 2745518:HU722_RS16535
uniprot id: A0A8I0CYW6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS04025
gene id: 2745518:HU722_RS04025
uniprot id: A0A8I0CUW8
names: Similarity
messages: Belongs to the SUI1 family.

2745518:HU722 RS03190
gene id: 2745518:HU722_RS03190
uniprot id: A0A8I0CV28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

2745518:HU722 RS06230
gene id: 2745518:HU722_RS06230
uniprot id: A0A8H9YT11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS05515
gene id: 2745518:HU722_RS05515
uniprot id: A0A8H9YUV7
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS06805
gene id: 2745518:HU722_RS06805
uniprot id: A0A8H9YXZ5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS14000
gene id: 2745518:HU722_RS14000
uniprot id: A0A8I0D0W0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS00930
gene id: 2745518:HU722_RS00930
uniprot id: A0A8I0CXZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

2745518:HU722 RS20770
gene id: 2745518:HU722_RS20770
uniprot id: A0A8H9YM54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

2745518:HU722 RS25525
gene id: 2745518:HU722_RS25525
uniprot id: A0A8I0CVZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS24680
gene id: 2745518:HU722_RS24680
uniprot id: A0A8I0D244
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS25605
gene id: 2745518:HU722_RS25605
uniprot id: A0A8I0CWG9
names: Function
names: Subunit
messages: Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
messages: Monomer in both c-di-GMP-bound and free forms.

2745518:HU722 RS28680
gene id: 2745518:HU722_RS28680
uniprot id: A0A8H9YXP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS07570
gene id: 2745518:HU722_RS07570
uniprot id: A0A8H9Z2Z7
names: Subcellular Location Annotation
messages: Cytoplasm

2745518:HU722 RS14395
gene id: 2745518:HU722_RS14395
uniprot id: A0A8H9YY44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I38 family.
messages: Periplasm

2745518:HU722 RS28280
gene id: 2745518:HU722_RS28280
uniprot id: A0A8I0D102
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

2745518:HU722 RS09130
gene id: 2745518:HU722_RS09130
uniprot id: A0A8H9YSB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS26315
gene id: 2745518:HU722_RS26315
uniprot id: A0A8H9YRC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

2745518:HU722 RS05800
gene id: 2745518:HU722_RS05800
uniprot id: A0A8H9YUE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

2745518:HU722 RS23670
gene id: 2745518:HU722_RS23670
uniprot id: A0A8I0CUS2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

2745518:HU722 RS27130
gene id: 2745518:HU722_RS27130
uniprot id: A0A8H9YSQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2745518:HU722 RS07340
gene id: 2745518:HU722_RS07340
uniprot id: A0A8H9YXC0
names: Subcellular Location Annotation
messages: Cytoplasm

2745518:HU722 RS18375
gene id: 2745518:HU722_RS18375
uniprot id: A0A8H9YQJ5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745518:HU722 RS00915
gene id: 2745518:HU722_RS00915
uniprot id: A0A8I0CZ27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

2745518:HU722 RS10050
gene id: 2745518:HU722_RS10050
uniprot id: A0A8I0CXI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS10465
gene id: 2745518:HU722_RS10465
uniprot id: A0A8H9Z398
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

2745518:HU722 RS05920
gene id: 2745518:HU722_RS05920
uniprot id: A0A8I0CY90
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS05250
gene id: 2745518:HU722_RS05250
uniprot id: A0A8H9Z372
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

2745518:HU722 RS23925
gene id: 2745518:HU722_RS23925
uniprot id: A0A8I0D0T3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

2745518:HU722 RS10225
gene id: 2745518:HU722_RS10225
uniprot id: A0A8H9Z388
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS27020
gene id: 2745518:HU722_RS27020
uniprot id: A0A8I0CXG4
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

2745518:HU722 RS23495
gene id: 2745518:HU722_RS23495
uniprot id: A0A8H9YLX0
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

2745518:HU722 RS07640
gene id: 2745518:HU722_RS07640
uniprot id: A0A8H9Z367
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2745518:HU722 RS01010
gene id: 2745518:HU722_RS01010
uniprot id: A0A8H9YWI5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2745518:HU722 RS20405
gene id: 2745518:HU722_RS20405
uniprot id: A0A8H9YYC9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2745518:HU722 RS20070
gene id: 2745518:HU722_RS20070
uniprot id: A0A8H9Z089
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
messages: Cell membrane
messages: Homotetramer.

2745518:HU722 RS22690
gene id: 2745518:HU722_RS22690
uniprot id: A0A8H9YJM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

2745518:HU722 RS14190
gene id: 2745518:HU722_RS14190
uniprot id: A0A8H9YZJ1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS02010
gene id: 2745518:HU722_RS02010
uniprot id: A0A8H9YZ95
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

2745518:HU722 RS12405
gene id: 2745518:HU722_RS12405
uniprot id: A0A8H9Z2W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

2745518:HU722 RS19250
gene id: 2745518:HU722_RS19250
uniprot id: A0A8H9YZL9
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

2745518:HU722 RS08465
gene id: 2745518:HU722_RS08465
uniprot id: A0A8H9YZ98
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS17975
gene id: 2745518:HU722_RS17975
uniprot id: A0A8I0CWD9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

2745518:HU722 RS06710
gene id: 2745518:HU722_RS06710
uniprot id: A0A8I0CZC7
names: Similarity
messages: Belongs to the glutamate synthase family.

2745518:HU722 RS14505
gene id: 2745518:HU722_RS14505
uniprot id: A0A8H9YZ39
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

2745518:HU722 RS25715
gene id: 2745518:HU722_RS25715
uniprot id: A0A8H9YR15
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

2745518:HU722 RS03725
gene id: 2745518:HU722_RS03725
uniprot id: A0A8I0CUZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

2745518:HU722 RS21400
gene id: 2745518:HU722_RS21400
uniprot id: A0A8H9YJ47
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

2745518:HU722 RS21340
gene id: 2745518:HU722_RS21340
uniprot id: A0A8H9YLA4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745518:HU722 RS21100
gene id: 2745518:HU722_RS21100
uniprot id: A0A8H9YIA5
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

2745518:HU722 RS15550
gene id: 2745518:HU722_RS15550
uniprot id: A0A8I0CZK6
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

2745518:HU722 RS23780
gene id: 2745518:HU722_RS23780
uniprot id: A0A8H9YMU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

2745518:HU722 RS15205
gene id: 2745518:HU722_RS15205
uniprot id: A0A8H9YWY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell membrane

2745518:HU722 RS17295
gene id: 2745518:HU722_RS17295
uniprot id: A0A8H9YQ63
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

2745518:HU722 RS14335
gene id: 2745518:HU722_RS14335
uniprot id: A0A8H9YZ13
names: Similarity
messages: Belongs to the pirin family.

2745518:HU722 RS27825
gene id: 2745518:HU722_RS27825
uniprot id: A0A8H9YRH6
names: Similarity
messages: Belongs to the YggT family.

2745518:HU722 RS24385
gene id: 2745518:HU722_RS24385
uniprot id: A0A8I0D1C8
names: Similarity
messages: Belongs to the MlaA family.

2745518:HU722 RS14590
gene id: 2745518:HU722_RS14590
uniprot id: A0A8I0D183
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

2745518:HU722 RS03660
gene id: 2745518:HU722_RS03660
uniprot id: A0A8I0CUF7
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

2745518:HU722 RS05355
gene id: 2745518:HU722_RS05355
uniprot id: A0A8H9Z223
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

2745518:HU722 RS28735
gene id: 2745518:HU722_RS28735
uniprot id: A0A8I0D075
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745518:HU722 RS18400
gene id: 2745518:HU722_RS18400
uniprot id: A0A8H9YSH8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS27805
gene id: 2745518:HU722_RS27805
uniprot id: A0A8H9YT54
names: Similarity
messages: Belongs to the peptidase C40 family.

2745518:HU722 RS24220
gene id: 2745518:HU722_RS24220
uniprot id: A0A8I0D1D7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

2745518:HU722 RS21655
gene id: 2745518:HU722_RS21655
uniprot id: A0A8H9YMF0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

2745518:HU722 RS18205
gene id: 2745518:HU722_RS18205
uniprot id: A0A8I0CWX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS27700
gene id: 2745518:HU722_RS27700
uniprot id: A0A8I0CXB9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MdcC family.
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm
messages: Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.

2745518:HU722 RS21685
gene id: 2745518:HU722_RS21685
uniprot id: A0A8I0CUC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

2745518:HU722 RS22940
gene id: 2745518:HU722_RS22940
uniprot id: A0A8H9YM32
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS16045
gene id: 2745518:HU722_RS16045
uniprot id: A0A8I0D033
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS05055
gene id: 2745518:HU722_RS05055
uniprot id: A0A8H9Z3B5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

2745518:HU722 RS22660
gene id: 2745518:HU722_RS22660
uniprot id: A0A8H9YMW3
names: Similarity
messages: Belongs to the aspartokinase family.

2745518:HU722 RS22285
gene id: 2745518:HU722_RS22285
uniprot id: A0A8I0CTS8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS26020
gene id: 2745518:HU722_RS26020
uniprot id: A0A8H9YR44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

2745518:HU722 RS28980
gene id: 2745518:HU722_RS28980
uniprot id: A0A8H9YRW9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

2745518:HU722 RS13765
gene id: 2745518:HU722_RS13765
uniprot id: A0A8I0D2T7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS13280
gene id: 2745518:HU722_RS13280
uniprot id: A0A8H9Z0K1
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS06235
gene id: 2745518:HU722_RS06235
uniprot id: A0A8H9YSY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS03975
gene id: 2745518:HU722_RS03975
uniprot id: A0A8F4X0X1
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

2745518:HU722 RS27305
gene id: 2745518:HU722_RS27305
uniprot id: A0A8H9YR50
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

2745518:HU722 RS13770
gene id: 2745518:HU722_RS13770
uniprot id: A0A8I0D235
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

2745518:HU722 RS20175
gene id: 2745518:HU722_RS20175
uniprot id: A0A8H9YYD7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2745518:HU722 RS27055
gene id: 2745518:HU722_RS27055
uniprot id: A0A8H9YSR4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745518:HU722 RS20955
gene id: 2745518:HU722_RS20955
uniprot id: A0A8H9YIT2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

2745518:HU722 RS14390
gene id: 2745518:HU722_RS14390
uniprot id: A0A8F4WS25
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10B family.
messages: Binds 1 zinc ion per subunit.

2745518:HU722 RS11995
gene id: 2745518:HU722_RS11995
uniprot id: A0A8H9Z087
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

2745518:HU722 RS07965
gene id: 2745518:HU722_RS07965
uniprot id: A0A8I0D2G2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745518:HU722 RS03550
gene id: 2745518:HU722_RS03550
uniprot id: A0A8H9YMC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS07410
gene id: 2745518:HU722_RS07410
uniprot id: A0A8H9Z281
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

2745518:HU722 RS04230
gene id: 2745518:HU722_RS04230
uniprot id: A0A8H9YM35
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

2745518:HU722 RS13255
gene id: 2745518:HU722_RS13255
uniprot id: A0A8H9YYH3
names: Similarity
messages: Belongs to the peptidase M1 family.

2745518:HU722 RS09595
gene id: 2745518:HU722_RS09595
uniprot id: A0A8I0CXR2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS04875
gene id: 2745518:HU722_RS04875
uniprot id: A0A8H9Z360
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

2745518:HU722 RS02750
gene id: 2745518:HU722_RS02750
uniprot id: A0A8I0CUL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

2745518:HU722 RS18000
gene id: 2745518:HU722_RS18000
uniprot id: A0A8H9YQF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745518:HU722 RS11095
gene id: 2745518:HU722_RS11095
uniprot id: A0A8H9YVF8
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS18870
gene id: 2745518:HU722_RS18870
uniprot id: A0A8H9YZR2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS07300
gene id: 2745518:HU722_RS07300
uniprot id: A0A8I0CZT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

2745518:HU722 RS17775
gene id: 2745518:HU722_RS17775
uniprot id: A0A8H9YQC0
names: Similarity
messages: Belongs to the WrbA family.

2745518:HU722 RS01190
gene id: 2745518:HU722_RS01190
uniprot id: A0A8H9YUX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

2745518:HU722 RS25820
gene id: 2745518:HU722_RS25820
uniprot id: A0A8I0CW24
names: Similarity
messages: Belongs to the DEAD box helicase family.

2745518:HU722 RS06470
gene id: 2745518:HU722_RS06470
uniprot id: A0A8H9YTL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

2745518:HU722 RS28705
gene id: 2745518:HU722_RS28705
uniprot id: A0A8H9YZ63
names: Similarity
messages: Belongs to the UPF0047 family.

2745518:HU722 RS28060
gene id: 2745518:HU722_RS28060
uniprot id: A0A8I0D2G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

2745518:HU722 RS02800
gene id: 2745518:HU722_RS02800
uniprot id: A0A8H9YMN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS25095
gene id: 2745518:HU722_RS25095
uniprot id: A0A8H9YPP5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS06640
gene id: 2745518:HU722_RS06640
uniprot id: A0A8I0CZB6
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

2745518:HU722 RS28040
gene id: 2745518:HU722_RS28040
uniprot id: A0A8H9Z4L7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS11175
gene id: 2745518:HU722_RS11175
uniprot id: A0A8H9YUR6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

2745518:HU722 RS07745
gene id: 2745518:HU722_RS07745
uniprot id: A0A8I0D2F0
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme may modulate central metabolism.
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

2745518:HU722 RS14090
gene id: 2745518:HU722_RS14090
uniprot id: A0A8F4WTL1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DyP-type peroxidase family. EfeB subfamily.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Homodimer. Part of a ferrous iron transporter composed of EfeU, EfeO and EfeB.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.
messages: Periplasm

2745518:HU722 RS21225
gene id: 2745518:HU722_RS21225
uniprot id: A0A8I0CTK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

2745518:HU722 RS05910
gene id: 2745518:HU722_RS05910
uniprot id: A0A8I0CXS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2745518:HU722 RS16200
gene id: 2745518:HU722_RS16200
uniprot id: A0A8H9YWJ9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS04865
gene id: 2745518:HU722_RS04865
uniprot id: A0A8H9Z2Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

2745518:HU722 RS24720
gene id: 2745518:HU722_RS24720
uniprot id: A0A8H9Z234
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

2745518:HU722 RS10735
gene id: 2745518:HU722_RS10735
uniprot id: A0A8H9YU00
names: Similarity
messages: Belongs to the VgrG protein family.

2745518:HU722 RS07030
gene id: 2745518:HU722_RS07030
uniprot id: A0A8H9YWY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

2745518:HU722 RS19285
gene id: 2745518:HU722_RS19285
uniprot id: A0A8H9YYN2
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

2745518:HU722 RS00160
gene id: 2745518:HU722_RS00160
uniprot id: A0A8H9YXU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2745518:HU722 RS20540
gene id: 2745518:HU722_RS20540
uniprot id: A0A8I0D0Z1
names: Similarity
messages: Belongs to the peptidase M18 family.

2745518:HU722 RS03470
gene id: 2745518:HU722_RS03470
uniprot id: A0A8H9YMR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

2745518:HU722 RS19965
gene id: 2745518:HU722_RS19965
uniprot id: A0A8H9YZV7
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS06550
gene id: 2745518:HU722_RS06550
uniprot id: A0A8H9YU84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

2745518:HU722 RS11075
gene id: 2745518:HU722_RS11075
uniprot id: A0A8H9YVR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2745518:HU722 RS13915
gene id: 2745518:HU722_RS13915
uniprot id: A0A8I0D0B3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS07070
gene id: 2745518:HU722_RS07070
uniprot id: A0A8H9YVV6
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

2745518:HU722 RS02490
gene id: 2745518:HU722_RS02490
uniprot id: A0A8H9YXG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS04545
gene id: 2745518:HU722_RS04545
uniprot id: A0A8H9YLZ2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS04130
gene id: 2745518:HU722_RS04130
uniprot id: A0A8H9YNP0
names: Similarity
messages: Belongs to the bacterial secretin family.

2745518:HU722 RS19040
gene id: 2745518:HU722_RS19040
uniprot id: A0A8H9YZP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS27630
gene id: 2745518:HU722_RS27630
uniprot id: A0A8I0CWU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS20740
gene id: 2745518:HU722_RS20740
uniprot id: A0A8H9YJQ6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

2745518:HU722 RS03705
gene id: 2745518:HU722_RS03705
uniprot id: A0A8H9YMA5
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

2745518:HU722 RS17725
gene id: 2745518:HU722_RS17725
uniprot id: A0A8H9YS77
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS03455
gene id: 2745518:HU722_RS03455
uniprot id: A0A8H9YNS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

2745518:HU722 RS10035
gene id: 2745518:HU722_RS10035
uniprot id: A0A8H9YRD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

2745518:HU722 RS00350
gene id: 2745518:HU722_RS00350
uniprot id: A0A8I0CZK9
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

2745518:HU722 RS05490
gene id: 2745518:HU722_RS05490
uniprot id: A0A8H9YTV5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2745518:HU722 RS28720
gene id: 2745518:HU722_RS28720
uniprot id: A0A8H9YZQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

2745518:HU722 RS11195
gene id: 2745518:HU722_RS11195
uniprot id: A0A8H9YTN8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

2745518:HU722 RS18265
gene id: 2745518:HU722_RS18265
uniprot id: A0A8I0CVW0
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS01385
gene id: 2745518:HU722_RS01385
uniprot id: A0A8H9YWE1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

2745518:HU722 RS13115
gene id: 2745518:HU722_RS13115
uniprot id: A0A8H9YZD2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS03690
gene id: 2745518:HU722_RS03690
uniprot id: A0A8H9YNP3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2745518:HU722 RS27415
gene id: 2745518:HU722_RS27415
uniprot id: A0A8H9YTA0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS06690
gene id: 2745518:HU722_RS06690
uniprot id: A0A8H9YW03
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS20155
gene id: 2745518:HU722_RS20155
uniprot id: A0A8I0D0F2
names: Similarity
messages: Belongs to the UPF0270 family.

2745518:HU722 RS07845
gene id: 2745518:HU722_RS07845
uniprot id: A0A8H9Z1Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

2745518:HU722 RS11035
gene id: 2745518:HU722_RS11035
uniprot id: A0A8H9YTV6
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

2745518:HU722 RS02005
gene id: 2745518:HU722_RS02005
uniprot id: A0A8H9YZ34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

2745518:HU722 RS16960
gene id: 2745518:HU722_RS16960
uniprot id: A0A8H9Z3X7
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

2745518:HU722 RS18250
gene id: 2745518:HU722_RS18250
uniprot id: A0A8H9YSG3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2745518:HU722 RS03995
gene id: 2745518:HU722_RS03995
uniprot id: A0A8H9YMU6
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

2745518:HU722 RS08605
gene id: 2745518:HU722_RS08605
uniprot id: A0A8H9YZE1
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

2745518:HU722 RS13510
gene id: 2745518:HU722_RS13510
uniprot id: A0A8H9Z0N3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2745518:HU722 RS07810
gene id: 2745518:HU722_RS07810
uniprot id: A0A8I0D1V8
names: Similarity
messages: Belongs to the leucine-binding protein family.

2745518:HU722 RS09850
gene id: 2745518:HU722_RS09850
uniprot id: A0A8H9YSJ3
names: Similarity
messages: Belongs to the pyruvate kinase family.

2745518:HU722 RS11785
gene id: 2745518:HU722_RS11785
uniprot id: A0A8H9Z177
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

2745518:HU722 RS15350
gene id: 2745518:HU722_RS15350
uniprot id: A0A8H9YWB1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

2745518:HU722 RS10600
gene id: 2745518:HU722_RS10600
uniprot id: A0A8I0CYV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

2745518:HU722 RS06765
gene id: 2745518:HU722_RS06765
uniprot id: A0A8H9YW54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

2745518:HU722 RS26445
gene id: 2745518:HU722_RS26445
uniprot id: A0A8H9YPL2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS22795
gene id: 2745518:HU722_RS22795
uniprot id: A0A8H9YMH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS07065
gene id: 2745518:HU722_RS07065
uniprot id: A0A8H9YVV9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS01135
gene id: 2745518:HU722_RS01135
uniprot id: A0A8I0CZ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

2745518:HU722 RS20210
gene id: 2745518:HU722_RS20210
uniprot id: A0A8H9Z0D1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2745518:HU722 RS22235
gene id: 2745518:HU722_RS22235
uniprot id: A0A8H9YK48
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2745518:HU722 RS06510
gene id: 2745518:HU722_RS06510
uniprot id: A0A8I0CXX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

2745518:HU722 RS22905
gene id: 2745518:HU722_RS22905
uniprot id: A0A8I0CU24
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745518:HU722 RS02220
gene id: 2745518:HU722_RS02220
uniprot id: A0A8I0CZF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745518:HU722 RS05645
gene id: 2745518:HU722_RS05645
uniprot id: A0A8H9YUG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

2745518:HU722 RS01255
gene id: 2745518:HU722_RS01255
uniprot id: A0A8H9YW68
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

2745518:HU722 RS17410
gene id: 2745518:HU722_RS17410
uniprot id: A0A8H9YS33
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

2745518:HU722 RS16890
gene id: 2745518:HU722_RS16890
uniprot id: A0A8I0D1G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745518:HU722 RS19540
gene id: 2745518:HU722_RS19540
uniprot id: A0A8H9Z4T2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745518:HU722 RS18850
gene id: 2745518:HU722_RS18850
uniprot id: A0A8I0D0S6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2745518:HU722 RS09115
gene id: 2745518:HU722_RS09115
uniprot id: A0A8H9YTA3
names: Similarity
messages: Belongs to the peptidase S33 family.

2745518:HU722 RS20705
gene id: 2745518:HU722_RS20705
uniprot id: A0A8I0CTE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
messages: Binds 1 Mg(2+) ion per subunit. Ca(2+) may be able to substitute.
messages: Cytoplasm
messages: Probably phosphorylates lipids; the in vivo substrate is unknown.

2745518:HU722 RS03670
gene id: 2745518:HU722_RS03670
uniprot id: A0A8H9YND5
names: Similarity
messages: Belongs to the leucine-binding protein family.

2745518:HU722 RS06080
gene id: 2745518:HU722_RS06080
uniprot id: A0A8H9YSY7
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS08290
gene id: 2745518:HU722_RS08290
uniprot id: A0A8H9YYP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

2745518:HU722 RS08395
gene id: 2745518:HU722_RS08395
uniprot id: A0A8I0CZX5
names: Subcellular Location Annotation
messages: Membrane

2745518:HU722 RS07355
gene id: 2745518:HU722_RS07355
uniprot id: A0A8H9YW60
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

2745518:HU722 RS12665
gene id: 2745518:HU722_RS12665
uniprot id: A0A8H9Z0X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

2745518:HU722 RS24400
gene id: 2745518:HU722_RS24400
uniprot id: A0A8H9Z101
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2745518:HU722 RS11430
gene id: 2745518:HU722_RS11430
uniprot id: A0A8I0CYQ1
names: Similarity
messages: Belongs to the IucA/IucC family.

2745518:HU722 RS26635
gene id: 2745518:HU722_RS26635
uniprot id: A0A8H9YRT8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2745518:HU722 RS22675
gene id: 2745518:HU722_RS22675
uniprot id: A0A8I0CTZ6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745518:HU722 RS02405
gene id: 2745518:HU722_RS02405
uniprot id: A0A8H9YXT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS27385
gene id: 2745518:HU722_RS27385
uniprot id: A0A8H9YR25
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

2745518:HU722 RS24875
gene id: 2745518:HU722_RS24875
uniprot id: A0A8H9YQP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

2745518:HU722 RS18015
gene id: 2745518:HU722_RS18015
uniprot id: A0A8H9YRU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

2745518:HU722 RS20255
gene id: 2745518:HU722_RS20255
uniprot id: A0A8H9YYA3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

2745518:HU722 RS24295
gene id: 2745518:HU722_RS24295
uniprot id: A0A8I0D1Z0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745518:HU722 RS03330
gene id: 2745518:HU722_RS03330
uniprot id: A0A8I0CVS4
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

2745518:HU722 RS23275
gene id: 2745518:HU722_RS23275
uniprot id: A0A8I0CT89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

2745518:HU722 RS07495
gene id: 2745518:HU722_RS07495
uniprot id: A0A8H9Z2Y5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

2745518:HU722 RS18185
gene id: 2745518:HU722_RS18185
uniprot id: A0A8H9YSE8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2745518:HU722 RS22595
gene id: 2745518:HU722_RS22595
uniprot id: A0A8I0CUV8
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

2745518:HU722 RS07190
gene id: 2745518:HU722_RS07190
uniprot id: A0A8H9YXE3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

2745518:HU722 RS05785
gene id: 2745518:HU722_RS05785
uniprot id: A0A8H9YTB1
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

2745518:HU722 RS26950
gene id: 2745518:HU722_RS26950
uniprot id: A0A8I0CWY7
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

2745518:HU722 RS20525
gene id: 2745518:HU722_RS20525
uniprot id: A0A8I0CZV5
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

2745518:HU722 RS17000
gene id: 2745518:HU722_RS17000
uniprot id: A0A8I0D3D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

2745518:HU722 RS09395
gene id: 2745518:HU722_RS09395
uniprot id: A0A8H9YTT0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

2745518:HU722 RS02100
gene id: 2745518:HU722_RS02100
uniprot id: A0A8H9YYJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane