2745514:HU731 RS12405
gene id: 2745514:HU731_RS12405
uniprot id: A0A9E6T8H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2745514:HU731 RS21970
gene id: 2745514:HU731_RS21970
uniprot id: A0A9E6NBM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

2745514:HU731 RS05755
gene id: 2745514:HU731_RS05755
uniprot id: A0A9E6NG56
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2745514:HU731 RS23515
gene id: 2745514:HU731_RS23515
uniprot id: A0A9E6ND08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

2745514:HU731 RS20820
gene id: 2745514:HU731_RS20820
uniprot id: A0A9E6NB78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

2745514:HU731 RS22005
gene id: 2745514:HU731_RS22005
uniprot id: A0A9E6T563
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745514:HU731 RS24505
gene id: 2745514:HU731_RS24505
uniprot id: A0A9E6NCP1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745514:HU731 RS23710
gene id: 2745514:HU731_RS23710
uniprot id: A0A9E6NCD0
names: Similarity
messages: Belongs to the MlaA family.

2745514:HU731 RS15065
gene id: 2745514:HU731_RS15065
uniprot id: A0A9E6T3S1
names: Similarity
messages: Belongs to the P(II) protein family.

2745514:HU731 RS20395
gene id: 2745514:HU731_RS20395
uniprot id: A0A9E6NBW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

2745514:HU731 RS17760
gene id: 2745514:HU731_RS17760
uniprot id: A0A9E6NA76
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

2745514:HU731 RS20225
gene id: 2745514:HU731_RS20225
uniprot id: A0A9E6NAY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS17610
gene id: 2745514:HU731_RS17610
uniprot id: A0A9E6NJT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS11400
gene id: 2745514:HU731_RS11400
uniprot id: A0A9E6NHY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

2745514:HU731 RS13530
gene id: 2745514:HU731_RS13530
uniprot id: A0A9E6NIT1
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

2745514:HU731 RS18080
gene id: 2745514:HU731_RS18080
uniprot id: A0A9E6NAH8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

2745514:HU731 RS17565
gene id: 2745514:HU731_RS17565
uniprot id: A0A9E6T4A8
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

2745514:HU731 RS15820
gene id: 2745514:HU731_RS15820
uniprot id: A0A9E6N9M6
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

2745514:HU731 RS17820
gene id: 2745514:HU731_RS17820
uniprot id: A0A9E6T4B3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS05980
gene id: 2745514:HU731_RS05980
uniprot id: A0A9E6NFS5
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS07155
gene id: 2745514:HU731_RS07155
uniprot id: A0A9E6NK10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

2745514:HU731 RS09825
gene id: 2745514:HU731_RS09825
uniprot id: A0A9E6NH94
names: Similarity
messages: Belongs to the Dps family.

2745514:HU731 RS04470
gene id: 2745514:HU731_RS04470
uniprot id: A0A9E6NGD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745514:HU731 RS24465
gene id: 2745514:HU731_RS24465
uniprot id: A0A9E6NCI8
names: Similarity
messages: Belongs to the YkuD family.

2745514:HU731 RS23575
gene id: 2745514:HU731_RS23575
uniprot id: A0A9E6T5A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

2745514:HU731 RS09600
gene id: 2745514:HU731_RS09600
uniprot id: A0A9E6T7Z1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

2745514:HU731 RS19695
gene id: 2745514:HU731_RS19695
uniprot id: A0A9E6T4R1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

2745514:HU731 RS15800
gene id: 2745514:HU731_RS15800
uniprot id: A0A9E6N9L8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

2745514:HU731 RS25405
gene id: 2745514:HU731_RS25405
uniprot id: A0A9E6NDH8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2745514:HU731 RS14565
gene id: 2745514:HU731_RS14565
uniprot id: A0A9E6T3L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745514:HU731 RS07355
gene id: 2745514:HU731_RS07355
uniprot id: A0A9E6T7L2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2745514:HU731 RS22450
gene id: 2745514:HU731_RS22450
uniprot id: A0A9E6NBS9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

2745514:HU731 RS10575
gene id: 2745514:HU731_RS10575
uniprot id: A0A9E6NHH3
names: Similarity
messages: Belongs to the HesB/IscA family.

2745514:HU731 RS19100
gene id: 2745514:HU731_RS19100
uniprot id: A0A9E6NAZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

2745514:HU731 RS27175
gene id: 2745514:HU731_RS27175
uniprot id: A0A9E6T5V0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745514:HU731 RS15285
gene id: 2745514:HU731_RS15285
uniprot id: A0A9E6T3X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

2745514:HU731 RS22525
gene id: 2745514:HU731_RS22525
uniprot id: A0A9E6NC58
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2745514:HU731 RS05975
gene id: 2745514:HU731_RS05975
uniprot id: A0A9E6T773
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS07765
gene id: 2745514:HU731_RS07765
uniprot id: A0A9E6NHH8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

2745514:HU731 RS20315
gene id: 2745514:HU731_RS20315
uniprot id: A0A9E6NBV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2745514:HU731 RS15635
gene id: 2745514:HU731_RS15635
uniprot id: A0A9E6N9Y4
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

2745514:HU731 RS24025
gene id: 2745514:HU731_RS24025
uniprot id: A0A9E6NCA7
names: Similarity
messages: Belongs to the MQO family.

2745514:HU731 RS11880
gene id: 2745514:HU731_RS11880
uniprot id: A0A9E6NI47
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745514:HU731 RS00220
gene id: 2745514:HU731_RS00220
uniprot id: A0A9E6NES7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

2745514:HU731 RS19775
gene id: 2745514:HU731_RS19775
uniprot id: A0A9E6T4R6
names: Similarity
messages: Belongs to the CFA/CMAS family.

2745514:HU731 RS07550
gene id: 2745514:HU731_RS07550
uniprot id: A0A9E6NHG4
names: Similarity
messages: Belongs to the peptidase C40 family.

2745514:HU731 RS20565
gene id: 2745514:HU731_RS20565
uniprot id: A0A9E6NBP6
names: Similarity
messages: Belongs to the BolA/IbaG family.

2745514:HU731 RS19620
gene id: 2745514:HU731_RS19620
uniprot id: A0A9E6T4N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS15480
gene id: 2745514:HU731_RS15480
uniprot id: A0A9E6NA17
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Cytoplasm

2745514:HU731 RS15540
gene id: 2745514:HU731_RS15540
uniprot id: A0A9E6T3V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

2745514:HU731 RS11680
gene id: 2745514:HU731_RS11680
uniprot id: A0A9E6NHY3
names: Similarity
messages: Belongs to the peptidase S16 family.

2745514:HU731 RS12645
gene id: 2745514:HU731_RS12645
uniprot id: A0A9E6T8I5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2745514:HU731 RS11905
gene id: 2745514:HU731_RS11905
uniprot id: A0A9E6NI07
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS13145
gene id: 2745514:HU731_RS13145
uniprot id: A0A9E6T8F3
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

2745514:HU731 RS16065
gene id: 2745514:HU731_RS16065
uniprot id: A0A9E6N9T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

2745514:HU731 RS04615
gene id: 2745514:HU731_RS04615
uniprot id: A0A9E6T746
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS11560
gene id: 2745514:HU731_RS11560
uniprot id: A0A9E6NIP8
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

2745514:HU731 RS09055
gene id: 2745514:HU731_RS09055
uniprot id: A0A9E6NGW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS07230
gene id: 2745514:HU731_RS07230
uniprot id: A0A9E6NGC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

2745514:HU731 RS07130
gene id: 2745514:HU731_RS07130
uniprot id: A0A9E6NGB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

2745514:HU731 RS08795
gene id: 2745514:HU731_RS08795
uniprot id: A0A9E6NH96
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS27055
gene id: 2745514:HU731_RS27055
uniprot id: A0A9E6NEB4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745514:HU731 RS12410
gene id: 2745514:HU731_RS12410
uniprot id: A0A9E6T8B1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

2745514:HU731 RS22765
gene id: 2745514:HU731_RS22765
uniprot id: A0A9E6NC14
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

2745514:HU731 RS15245
gene id: 2745514:HU731_RS15245
uniprot id: A0A9E6N9Z3
names: Similarity
messages: Belongs to the YicC/YloC family.

2745514:HU731 RS12755
gene id: 2745514:HU731_RS12755
uniprot id: A0A9E6NIN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2745514:HU731 RS04345
gene id: 2745514:HU731_RS04345
uniprot id: A0A9E6T722
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2745514:HU731 RS11730
gene id: 2745514:HU731_RS11730
uniprot id: A0A9E6NI29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS20325
gene id: 2745514:HU731_RS20325
uniprot id: A0A9E6NB27
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

2745514:HU731 RS03960
gene id: 2745514:HU731_RS03960
uniprot id: A0A9E6NG71
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS15300
gene id: 2745514:HU731_RS15300
uniprot id: A0A9E6T3T6
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

2745514:HU731 RS09590
gene id: 2745514:HU731_RS09590
uniprot id: A0A9E6NH75
names: Subcellular Location Annotation
messages: Cytoplasm

2745514:HU731 RS18685
gene id: 2745514:HU731_RS18685
uniprot id: A0A9E6T4D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

2745514:HU731 RS02725
gene id: 2745514:HU731_RS02725
uniprot id: A0A9E6NER4
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS16055
gene id: 2745514:HU731_RS16055
uniprot id: A0A9E6N9Q4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

2745514:HU731 RS09555
gene id: 2745514:HU731_RS09555
uniprot id: A0A9E6NI34
names: Similarity
messages: Belongs to the carbamate kinase family.

2745514:HU731 RS18610
gene id: 2745514:HU731_RS18610
uniprot id: A0A9E6NAF7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2745514:HU731 RS11570
gene id: 2745514:HU731_RS11570
uniprot id: A0A9E6NI06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2745514:HU731 RS22775
gene id: 2745514:HU731_RS22775
uniprot id: A0A9E6NCG7
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS20595
gene id: 2745514:HU731_RS20595
uniprot id: A0A9E6T4X1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

2745514:HU731 RS07850
gene id: 2745514:HU731_RS07850
uniprot id: A0A9E6NHK1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

2745514:HU731 RS05785
gene id: 2745514:HU731_RS05785
uniprot id: A0A9E6T727
names: Subcellular Location Annotation
messages: Cytoplasm

2745514:HU731 RS21390
gene id: 2745514:HU731_RS21390
uniprot id: A0A9E6T533
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

2745514:HU731 RS28775
gene id: 2745514:HU731_RS28775
uniprot id: A0A9E6NDE3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS09350
gene id: 2745514:HU731_RS09350
uniprot id: A0A9E6NH48
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

2745514:HU731 RS07115
gene id: 2745514:HU731_RS07115
uniprot id: A0A9E6NG70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

2745514:HU731 RS20815
gene id: 2745514:HU731_RS20815
uniprot id: A0A9E6NBL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

2745514:HU731 RS10255
gene id: 2745514:HU731_RS10255
uniprot id: A0A9E6T7V0
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

2745514:HU731 RS14845
gene id: 2745514:HU731_RS14845
uniprot id: A0A9E6N9V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS23360
gene id: 2745514:HU731_RS23360
uniprot id: A0A9E6NC43
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

2745514:HU731 RS19840
gene id: 2745514:HU731_RS19840
uniprot id: A0A9E6NB30
names: Function
messages: Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions.

2745514:HU731 RS25610
gene id: 2745514:HU731_RS25610
uniprot id: A0A9E6T5P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

2745514:HU731 RS04920
gene id: 2745514:HU731_RS04920
uniprot id: A0A9E6NG16
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

2745514:HU731 RS07270
gene id: 2745514:HU731_RS07270
uniprot id: A0A9E6T7F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2745514:HU731 RS18680
gene id: 2745514:HU731_RS18680
uniprot id: A0A9E6T4G9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

2745514:HU731 RS21755
gene id: 2745514:HU731_RS21755
uniprot id: A0A9E6NBN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

2745514:HU731 RS19090
gene id: 2745514:HU731_RS19090
uniprot id: A0A9E6NAR1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

2745514:HU731 RS07420
gene id: 2745514:HU731_RS07420
uniprot id: A0A9E6T7F8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

2745514:HU731 RS24725
gene id: 2745514:HU731_RS24725
uniprot id: A0A9E6NCK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

2745514:HU731 RS04490
gene id: 2745514:HU731_RS04490
uniprot id: A0A9E6NFB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745514:HU731 RS16265
gene id: 2745514:HU731_RS16265
uniprot id: A0A9E6NA66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS14605
gene id: 2745514:HU731_RS14605
uniprot id: A0A9E6N8Z0
names: Similarity
messages: Belongs to the glutamine synthetase family.

2745514:HU731 RS15255
gene id: 2745514:HU731_RS15255
uniprot id: A0A9E6N9C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2745514:HU731 RS13905
gene id: 2745514:HU731_RS13905
uniprot id: A0A9E6NIW0
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

2745514:HU731 RS20740
gene id: 2745514:HU731_RS20740
uniprot id: A0A9E6NBU3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

2745514:HU731 RS00345
gene id: 2745514:HU731_RS00345
uniprot id: A0A9E6T6C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS08980
gene id: 2745514:HU731_RS08980
uniprot id: A0A9E6NGV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS10550
gene id: 2745514:HU731_RS10550
uniprot id: A0A9E6T851
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

2745514:HU731 RS02985
gene id: 2745514:HU731_RS02985
uniprot id: A0A9E6T6K9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

2745514:HU731 RS07545
gene id: 2745514:HU731_RS07545
uniprot id: A0A9E6NGG8
names: Similarity
messages: Belongs to the peptidase C40 family.

2745514:HU731 RS28790
gene id: 2745514:HU731_RS28790
uniprot id: A0A9E6NHL3
names: Subcellular Location Annotation
messages: Cytoplasm

2745514:HU731 RS22130
gene id: 2745514:HU731_RS22130
uniprot id: A0A9E6NBQ0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

2745514:HU731 RS10855
gene id: 2745514:HU731_RS10855
uniprot id: A0A9E6NI05
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane
messages: The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains.

2745514:HU731 RS08675
gene id: 2745514:HU731_RS08675
uniprot id: A0A9E6T7U7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2745514:HU731 RS12525
gene id: 2745514:HU731_RS12525
uniprot id: A0A9E6NJ59
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

2745514:HU731 RS09800
gene id: 2745514:HU731_RS09800
uniprot id: A0A9E6NI67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

2745514:HU731 RS25830
gene id: 2745514:HU731_RS25830
uniprot id: A0A9E6T5U8
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

2745514:HU731 RS10560
gene id: 2745514:HU731_RS10560
uniprot id: A0A9E6T7X0
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

2745514:HU731 RS21975
gene id: 2745514:HU731_RS21975
uniprot id: A0A9E6NC62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

2745514:HU731 RS06870
gene id: 2745514:HU731_RS06870
uniprot id: A0A9E6T791
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ureidoglycolate lyase family.
messages: Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.
messages: Homodimer.

2745514:HU731 RS26755
gene id: 2745514:HU731_RS26755
uniprot id: A0A9E6T5X0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

2745514:HU731 RS07110
gene id: 2745514:HU731_RS07110
uniprot id: A0A9E6T7E7
names: Similarity
messages: Belongs to the MotB family.

2745514:HU731 RS16410
gene id: 2745514:HU731_RS16410
uniprot id: A0A9E6N9V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

2745514:HU731 RS12620
gene id: 2745514:HU731_RS12620
uniprot id: A0A9E6NI99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2745514:HU731 RS05760
gene id: 2745514:HU731_RS05760
uniprot id: A0A9E6NFV2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2745514:HU731 RS22805
gene id: 2745514:HU731_RS22805
uniprot id: A0A9E6NBX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

2745514:HU731 RS23465
gene id: 2745514:HU731_RS23465
uniprot id: A0A9E6NCH3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745514:HU731 RS06700
gene id: 2745514:HU731_RS06700
uniprot id: A0A9E6NGK2
names: Similarity
messages: Belongs to the UPF0270 family.

2745514:HU731 RS23270
gene id: 2745514:HU731_RS23270
uniprot id: A0A9E6T583
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745514:HU731 RS16375
gene id: 2745514:HU731_RS16375
uniprot id: A0A9E6NA07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS12890
gene id: 2745514:HU731_RS12890
uniprot id: A0A9E6NIC2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

2745514:HU731 RS11450
gene id: 2745514:HU731_RS11450
uniprot id: A0A9E6T8B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

2745514:HU731 RS07280
gene id: 2745514:HU731_RS07280
uniprot id: A0A9E6NHB0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

2745514:HU731 RS21255
gene id: 2745514:HU731_RS21255
uniprot id: A0A9E6NBA9
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

2745514:HU731 RS19910
gene id: 2745514:HU731_RS19910
uniprot id: A0A9E6NB98
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

2745514:HU731 RS12605
gene id: 2745514:HU731_RS12605
uniprot id: A0A9E6NIH3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2745514:HU731 RS23640
gene id: 2745514:HU731_RS23640
uniprot id: A0A9E6NCR1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

2745514:HU731 RS22250
gene id: 2745514:HU731_RS22250
uniprot id: A0A9E6T516
names: Subcellular Location Annotation
messages: Cytoplasm

2745514:HU731 RS18785
gene id: 2745514:HU731_RS18785
uniprot id: A0A9E6NAK8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS08735
gene id: 2745514:HU731_RS08735
uniprot id: A0A9E6T7U1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

2745514:HU731 RS21830
gene id: 2745514:HU731_RS21830
uniprot id: A0A9E6NBP3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

2745514:HU731 RS04445
gene id: 2745514:HU731_RS04445
uniprot id: A0A9E6T6V0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

2745514:HU731 RS12790
gene id: 2745514:HU731_RS12790
uniprot id: A0A9E6T8B3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2745514:HU731 RS24710
gene id: 2745514:HU731_RS24710
uniprot id: A0A9E6NDH3
names: Similarity
messages: Belongs to the type III secretion exporter family.

2745514:HU731 RS08640
gene id: 2745514:HU731_RS08640
uniprot id: A0A9E6NGV1
names: Similarity
messages: Belongs to the fabD family.

2745514:HU731 RS05995
gene id: 2745514:HU731_RS05995
uniprot id: A0A9E6NFY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

2745514:HU731 RS18445
gene id: 2745514:HU731_RS18445
uniprot id: A0A9E6NAD9
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

2745514:HU731 RS08145
gene id: 2745514:HU731_RS08145
uniprot id: A0A9E6NHL0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745514:HU731 RS09755
gene id: 2745514:HU731_RS09755
uniprot id: A0A9E6NH93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

2745514:HU731 RS16480
gene id: 2745514:HU731_RS16480
uniprot id: A0A9E6T454
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

2745514:HU731 RS23570
gene id: 2745514:HU731_RS23570
uniprot id: A0A9E6T5F4
names: Function
names: Similarity
names: Subunit
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).
messages: In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.

2745514:HU731 RS10510
gene id: 2745514:HU731_RS10510
uniprot id: A0A9E6NIH7
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

2745514:HU731 RS12125
gene id: 2745514:HU731_RS12125
uniprot id: A0A9E6NIB2
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

2745514:HU731 RS21795
gene id: 2745514:HU731_RS21795
uniprot id: A0A9E6NBG9
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

2745514:HU731 RS12200
gene id: 2745514:HU731_RS12200
uniprot id: A0A9E6NI87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

2745514:HU731 RS19165
gene id: 2745514:HU731_RS19165
uniprot id: A0A9E6NBF7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS04015
gene id: 2745514:HU731_RS04015
uniprot id: A0A9E6T6S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745514:HU731 RS18595
gene id: 2745514:HU731_RS18595
uniprot id: A0A9E6T4D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

2745514:HU731 RS21800
gene id: 2745514:HU731_RS21800
uniprot id: A0A9E6NCC5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

2745514:HU731 RS28145
gene id: 2745514:HU731_RS28145
uniprot id: A0A9E6NDQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

2745514:HU731 RS09370
gene id: 2745514:HU731_RS09370
uniprot id: A0A9E6T7P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745514:HU731 RS04435
gene id: 2745514:HU731_RS04435
uniprot id: A0A9E6T726
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745514:HU731 RS17960
gene id: 2745514:HU731_RS17960
uniprot id: A0A9E6T4D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2745514:HU731 RS21680
gene id: 2745514:HU731_RS21680
uniprot id: A0A9E6NBM4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2745514:HU731 RS11195
gene id: 2745514:HU731_RS11195
uniprot id: A0A9E6T809
names: Similarity
messages: Belongs to the HIBADH-related family.

2745514:HU731 RS08495
gene id: 2745514:HU731_RS08495
uniprot id: A0A9E6NH62
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

2745514:HU731 RS06685
gene id: 2745514:HU731_RS06685
uniprot id: A0A9E6NG61
names: Similarity
messages: Belongs to the asparagine synthetase family.

2745514:HU731 RS04690
gene id: 2745514:HU731_RS04690
uniprot id: A0A9E6T750
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

2745514:HU731 RS14435
gene id: 2745514:HU731_RS14435
uniprot id: A0A9E6N8U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

2745514:HU731 RS20415
gene id: 2745514:HU731_RS20415
uniprot id: A0A9E6NBG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

2745514:HU731 RS12665
gene id: 2745514:HU731_RS12665
uniprot id: A0A9E6NJD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2745514:HU731 RS15135
gene id: 2745514:HU731_RS15135
uniprot id: A0A9E6T3X9
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

2745514:HU731 RS04900
gene id: 2745514:HU731_RS04900
uniprot id: A0A9E6NFW8
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

2745514:HU731 RS08750
gene id: 2745514:HU731_RS08750
uniprot id: A0A9E6T7V2
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

2745514:HU731 RS20570
gene id: 2745514:HU731_RS20570
uniprot id: A0A9E6NBI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS07625
gene id: 2745514:HU731_RS07625
uniprot id: A0A9E6NHH4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

2745514:HU731 RS20330
gene id: 2745514:HU731_RS20330
uniprot id: A0A9E6NBL8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

2745514:HU731 RS00325
gene id: 2745514:HU731_RS00325
uniprot id: A0A9E6T6B0
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

2745514:HU731 RS09540
gene id: 2745514:HU731_RS09540
uniprot id: A0A9E6T7Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

2745514:HU731 RS21660
gene id: 2745514:HU731_RS21660
uniprot id: A0A9E6NBJ4
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS16675
gene id: 2745514:HU731_RS16675
uniprot id: A0A9E6T450
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

2745514:HU731 RS11435
gene id: 2745514:HU731_RS11435
uniprot id: A0A9E6T8A9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

2745514:HU731 RS16030
gene id: 2745514:HU731_RS16030
uniprot id: A0A9E6NA94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

2745514:HU731 RS11045
gene id: 2745514:HU731_RS11045
uniprot id: A0A9E6T800
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

2745514:HU731 RS19580
gene id: 2745514:HU731_RS19580
uniprot id: A0A9E6NAV5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745514:HU731 RS03605
gene id: 2745514:HU731_RS03605
uniprot id: A0A9E6NF64
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

2745514:HU731 RS11830
gene id: 2745514:HU731_RS11830
uniprot id: A0A9E6NHZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS24755
gene id: 2745514:HU731_RS24755
uniprot id: A0A9E6T5P1
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

2745514:HU731 RS24500
gene id: 2745514:HU731_RS24500
uniprot id: A0A9E6NCH5
names: Similarity
messages: Belongs to the universal stress protein A family.

2745514:HU731 RS21805
gene id: 2745514:HU731_RS21805
uniprot id: A0A9E6NCB4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

2745514:HU731 RS00640
gene id: 2745514:HU731_RS00640
uniprot id: A0A9E6T697
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS14700
gene id: 2745514:HU731_RS14700
uniprot id: A0A9E6N906
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS20575
gene id: 2745514:HU731_RS20575
uniprot id: A0A9E6NB46
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

2745514:HU731 RS15850
gene id: 2745514:HU731_RS15850
uniprot id: A0A9E6T3Z7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

2745514:HU731 RS14980
gene id: 2745514:HU731_RS14980
uniprot id: A0A9E6T3W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

2745514:HU731 RS19635
gene id: 2745514:HU731_RS19635
uniprot id: A0A9E6T4N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Membrane

2745514:HU731 RS19965
gene id: 2745514:HU731_RS19965
uniprot id: A0A9E6NBR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

2745514:HU731 RS23220
gene id: 2745514:HU731_RS23220
uniprot id: A0A9E6NC33
names: Similarity
messages: Belongs to the SAICAR synthetase family.

2745514:HU731 RS11025
gene id: 2745514:HU731_RS11025
uniprot id: A0A9E6NJU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS20590
gene id: 2745514:HU731_RS20590
uniprot id: A0A9E6NBQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

2745514:HU731 RS01305
gene id: 2745514:HU731_RS01305
uniprot id: A0A9E6NFA8
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS24930
gene id: 2745514:HU731_RS24930
uniprot id: A0A9E6NDP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

2745514:HU731 RS12195
gene id: 2745514:HU731_RS12195
uniprot id: A0A9E6NJ73
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

2745514:HU731 RS13635
gene id: 2745514:HU731_RS13635
uniprot id: A0A9E6NIK5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

2745514:HU731 RS10000
gene id: 2745514:HU731_RS10000
uniprot id: A0A9E6T7W8
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS23635
gene id: 2745514:HU731_RS23635
uniprot id: A0A9E6NCC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

2745514:HU731 RS12460
gene id: 2745514:HU731_RS12460
uniprot id: A0A9E6NI75
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

2745514:HU731 RS23605
gene id: 2745514:HU731_RS23605
uniprot id: A0A9E6ND77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

2745514:HU731 RS03835
gene id: 2745514:HU731_RS03835
uniprot id: A0A9E6NF87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745514:HU731 RS16720
gene id: 2745514:HU731_RS16720
uniprot id: A0A9E6N9Y2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

2745514:HU731 RS23150
gene id: 2745514:HU731_RS23150
uniprot id: A0A9E6NCX4
names: Function
names: Similarity
messages: An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
messages: Belongs to the SdhE FAD assembly factor family.

2745514:HU731 RS01280
gene id: 2745514:HU731_RS01280
uniprot id: A0A9E6T696
names: Similarity
messages: Belongs to the EfeM/EfeO family.

2745514:HU731 RS13070
gene id: 2745514:HU731_RS13070
uniprot id: A0A9E6T8L1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2745514:HU731 RS12750
gene id: 2745514:HU731_RS12750
uniprot id: A0A9E6NJ93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

2745514:HU731 RS03325
gene id: 2745514:HU731_RS03325
uniprot id: A0A9E6NEY4
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS09885
gene id: 2745514:HU731_RS09885
uniprot id: A0A9E6NHC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

2745514:HU731 RS04465
gene id: 2745514:HU731_RS04465
uniprot id: A0A9E6NGC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745514:HU731 RS20295
gene id: 2745514:HU731_RS20295
uniprot id: A0A9E6T4P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

2745514:HU731 RS09065
gene id: 2745514:HU731_RS09065
uniprot id: A0A9E6NI01
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS04460
gene id: 2745514:HU731_RS04460
uniprot id: A0A9E6NF88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

2745514:HU731 RS06765
gene id: 2745514:HU731_RS06765
uniprot id: A0A9E6NGH7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

2745514:HU731 RS23235
gene id: 2745514:HU731_RS23235
uniprot id: A0A9E6NCB5
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

2745514:HU731 RS00770
gene id: 2745514:HU731_RS00770
uniprot id: A0A9E6NE55
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

2745514:HU731 RS20795
gene id: 2745514:HU731_RS20795
uniprot id: A0A9E6NBZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS16470
gene id: 2745514:HU731_RS16470
uniprot id: A0A9E6T444
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

2745514:HU731 RS10865
gene id: 2745514:HU731_RS10865
uniprot id: A0A9E6NHN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

2745514:HU731 RS03240
gene id: 2745514:HU731_RS03240
uniprot id: A0A9E6T6Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS08280
gene id: 2745514:HU731_RS08280
uniprot id: A0A9E6T7H8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

2745514:HU731 RS11550
gene id: 2745514:HU731_RS11550
uniprot id: A0A9E6NJD8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

2745514:HU731 RS09365
gene id: 2745514:HU731_RS09365
uniprot id: A0A9E6T7T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745514:HU731 RS14045
gene id: 2745514:HU731_RS14045
uniprot id: A0A9E6NJW9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

2745514:HU731 RS10840
gene id: 2745514:HU731_RS10840
uniprot id: A0A9E6NIJ9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

2745514:HU731 RS08650
gene id: 2745514:HU731_RS08650
uniprot id: A0A9E6NGW7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2745514:HU731 RS23060
gene id: 2745514:HU731_RS23060
uniprot id: A0A9E6NC13
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

2745514:HU731 RS13935
gene id: 2745514:HU731_RS13935
uniprot id: A0A9E6T8K3
names: Similarity
messages: Belongs to the peptidase C40 family.

2745514:HU731 RS16345
gene id: 2745514:HU731_RS16345
uniprot id: A0A9E6NAE3
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

2745514:HU731 RS14025
gene id: 2745514:HU731_RS14025
uniprot id: A0A9E6T8S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

2745514:HU731 RS19340
gene id: 2745514:HU731_RS19340
uniprot id: A0A9E6NAU5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

2745514:HU731 RS00820
gene id: 2745514:HU731_RS00820
uniprot id: A0A9E6T6A4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS24895
gene id: 2745514:HU731_RS24895
uniprot id: A0A9E6T5P4
names: Similarity
messages: Belongs to the MlaA family.

2745514:HU731 RS19850
gene id: 2745514:HU731_RS19850
uniprot id: A0A9E6T4S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

2745514:HU731 RS04150
gene id: 2745514:HU731_RS04150
uniprot id: A0A9E6NG82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

2745514:HU731 RS04255
gene id: 2745514:HU731_RS04255
uniprot id: A0A9E6NFM2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

2745514:HU731 RS06800
gene id: 2745514:HU731_RS06800
uniprot id: A0A9E6T7C9
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

2745514:HU731 RS01250
gene id: 2745514:HU731_RS01250
uniprot id: A0A9E6NEB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

2745514:HU731 RS07520
gene id: 2745514:HU731_RS07520
uniprot id: A0A9E6T7M5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745514:HU731 RS14035
gene id: 2745514:HU731_RS14035
uniprot id: A0A9E6NIP3
names: Similarity
messages: Belongs to the peptidase M16 family.

2745514:HU731 RS13060
gene id: 2745514:HU731_RS13060
uniprot id: A0A9E6T8E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

2745514:HU731 RS18630
gene id: 2745514:HU731_RS18630
uniprot id: A0A9E6NAY5
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

2745514:HU731 RS11955
gene id: 2745514:HU731_RS11955
uniprot id: A0A9E6NI57
names: Similarity
messages: Belongs to the DEAD box helicase family.

2745514:HU731 RS12965
gene id: 2745514:HU731_RS12965
uniprot id: A0A9E6NID0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

2745514:HU731 RS08070
gene id: 2745514:HU731_RS08070
uniprot id: A0A9E6NHL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

2745514:HU731 RS16000
gene id: 2745514:HU731_RS16000
uniprot id: A0A9E6T424
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

2745514:HU731 RS08635
gene id: 2745514:HU731_RS08635
uniprot id: A0A9E6NH58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

2745514:HU731 RS25360
gene id: 2745514:HU731_RS25360
uniprot id: A0A9E6NDS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS25870
gene id: 2745514:HU731_RS25870
uniprot id: A0A9E6NDZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

2745514:HU731 RS13520
gene id: 2745514:HU731_RS13520
uniprot id: A0A9E6NJ37
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

2745514:HU731 RS21315
gene id: 2745514:HU731_RS21315
uniprot id: A0A9E6T4W4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745514:HU731 RS09780
gene id: 2745514:HU731_RS09780
uniprot id: A0A9E6T7R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2745514:HU731 RS18700
gene id: 2745514:HU731_RS18700
uniprot id: A0A9E6NB63
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

2745514:HU731 RS22400
gene id: 2745514:HU731_RS22400
uniprot id: A0A9E6T542
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

2745514:HU731 RS07350
gene id: 2745514:HU731_RS07350
uniprot id: A0A9E6T7C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

2745514:HU731 RS23290
gene id: 2745514:HU731_RS23290
uniprot id: A0A9E6NCX5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745514:HU731 RS11535
gene id: 2745514:HU731_RS11535
uniprot id: A0A9E6T829
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

2745514:HU731 RS12660
gene id: 2745514:HU731_RS12660
uniprot id: A0A9E6NIY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

2745514:HU731 RS08175
gene id: 2745514:HU731_RS08175
uniprot id: A0A9E6NH21
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

2745514:HU731 RS00420
gene id: 2745514:HU731_RS00420
uniprot id: A0A9E6T6D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745514:HU731 RS15980
gene id: 2745514:HU731_RS15980
uniprot id: A0A9E6N9P5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

2745514:HU731 RS12370
gene id: 2745514:HU731_RS12370
uniprot id: A0A9E6NI64
names: Similarity
messages: Belongs to the PspA/IM30 family.

2745514:HU731 RS07755
gene id: 2745514:HU731_RS07755
uniprot id: A0A9E6NGF8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745514:HU731 RS15825
gene id: 2745514:HU731_RS15825
uniprot id: A0A9E6N9R4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

2745514:HU731 RS13920
gene id: 2745514:HU731_RS13920
uniprot id: A0A9E6NIM8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

2745514:HU731 RS25335
gene id: 2745514:HU731_RS25335
uniprot id: A0A9E6T5N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS06610
gene id: 2745514:HU731_RS06610
uniprot id: A0A9E6NG48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
messages: Cell membrane
messages: Homotetramer.

2745514:HU731 RS25715
gene id: 2745514:HU731_RS25715
uniprot id: A0A9E6NDV9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745514:HU731 RS27150
gene id: 2745514:HU731_RS27150
uniprot id: A0A9E6NDC8
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Has an organic peroxide-dependent peroxidase activity.

2745514:HU731 RS16100
gene id: 2745514:HU731_RS16100
uniprot id: A0A9E6N9R7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

2745514:HU731 RS13825
gene id: 2745514:HU731_RS13825
uniprot id: A0A9E6NJL2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MdcC family.
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm
messages: Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.

2745514:HU731 RS15510
gene id: 2745514:HU731_RS15510
uniprot id: A0A9E6N9M7
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS12905
gene id: 2745514:HU731_RS12905
uniprot id: A0A9E6T8D9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2745514:HU731 RS20320
gene id: 2745514:HU731_RS20320
uniprot id: A0A9E6NBT4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2745514:HU731 RS22745
gene id: 2745514:HU731_RS22745
uniprot id: A0A9E6NCR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2.A.1.15) family.
messages: Membrane

2745514:HU731 RS07535
gene id: 2745514:HU731_RS07535
uniprot id: A0A9E6NHD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

2745514:HU731 RS25485
gene id: 2745514:HU731_RS25485
uniprot id: A0A9E6T5S7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

2745514:HU731 RS08780
gene id: 2745514:HU731_RS08780
uniprot id: A0A9E6NHW9
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

2745514:HU731 RS02290
gene id: 2745514:HU731_RS02290
uniprot id: A0A9E6T6G3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

2745514:HU731 RS14015
gene id: 2745514:HU731_RS14015
uniprot id: A0A9E6T8K8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

2745514:HU731 RS21115
gene id: 2745514:HU731_RS21115
uniprot id: A0A9E6NBD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS12915
gene id: 2745514:HU731_RS12915
uniprot id: A0A9E6T8K4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

2745514:HU731 RS11440
gene id: 2745514:HU731_RS11440
uniprot id: A0A9E6T859
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

2745514:HU731 RS17625
gene id: 2745514:HU731_RS17625
uniprot id: A0A9E6NAD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS15200
gene id: 2745514:HU731_RS15200
uniprot id: A0A9E6N9I8
names: Similarity
messages: Belongs to the UPF0758 family.

2745514:HU731 RS14630
gene id: 2745514:HU731_RS14630
uniprot id: A0A9E6N948
names: Function
names: Similarity
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.

2745514:HU731 RS08490
gene id: 2745514:HU731_RS08490
uniprot id: A0A9E6NGS9
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

2745514:HU731 RS18625
gene id: 2745514:HU731_RS18625
uniprot id: A0A9E6NAJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

2745514:HU731 RS15295
gene id: 2745514:HU731_RS15295
uniprot id: A0A9E6T3V6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745514:HU731 RS21355
gene id: 2745514:HU731_RS21355
uniprot id: A0A9E6NBY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

2745514:HU731 RS22375
gene id: 2745514:HU731_RS22375
uniprot id: A0A9E6NBV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

2745514:HU731 RS10955
gene id: 2745514:HU731_RS10955
uniprot id: A0A9E6T876
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

2745514:HU731 RS25095
gene id: 2745514:HU731_RS25095
uniprot id: A0A9E6NDL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2745514:HU731 RS02835
gene id: 2745514:HU731_RS02835
uniprot id: A0A9E6T6T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS07205
gene id: 2745514:HU731_RS07205
uniprot id: A0A9E6NH99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

2745514:HU731 RS24950
gene id: 2745514:HU731_RS24950
uniprot id: A0A9E6NCV7
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

2745514:HU731 RS22000
gene id: 2745514:HU731_RS22000
uniprot id: A0A9E6NC97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

2745514:HU731 RS23390
gene id: 2745514:HU731_RS23390
uniprot id: A0A9E6NCG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

2745514:HU731 RS18155
gene id: 2745514:HU731_RS18155
uniprot id: A0A9E6NAC5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

2745514:HU731 RS18275
gene id: 2745514:HU731_RS18275
uniprot id: A0A9E6T4E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

2745514:HU731 RS19875
gene id: 2745514:HU731_RS19875
uniprot id: A0A9E6T4Q1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2745514:HU731 RS20510
gene id: 2745514:HU731_RS20510
uniprot id: A0A9E6NB93
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

2745514:HU731 RS19460
gene id: 2745514:HU731_RS19460
uniprot id: A0A9E6T4N9
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

2745514:HU731 RS09500
gene id: 2745514:HU731_RS09500
uniprot id: A0A9E6NHF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

2745514:HU731 RS16520
gene id: 2745514:HU731_RS16520
uniprot id: A0A9E6N9Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

2745514:HU731 RS21785
gene id: 2745514:HU731_RS21785
uniprot id: A0A9E6T502
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

2745514:HU731 RS21410
gene id: 2745514:HU731_RS21410
uniprot id: A0A9E6T4Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

2745514:HU731 RS00310
gene id: 2745514:HU731_RS00310
uniprot id: A0A9E6NDU4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS23675
gene id: 2745514:HU731_RS23675
uniprot id: A0A9E6ND24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

2745514:HU731 RS13185
gene id: 2745514:HU731_RS13185
uniprot id: A0A9E6NJD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS23730
gene id: 2745514:HU731_RS23730
uniprot id: A0A9E6T5A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

2745514:HU731 RS27640
gene id: 2745514:HU731_RS27640
uniprot id: A0A9E6T626
names: Similarity
messages: Belongs to the hyi family.

2745514:HU731 RS15250
gene id: 2745514:HU731_RS15250
uniprot id: A0A9E6N9D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

2745514:HU731 RS19280
gene id: 2745514:HU731_RS19280
uniprot id: A0A9E6T4N5
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

2745514:HU731 RS22520
gene id: 2745514:HU731_RS22520
uniprot id: A0A9E6NCN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2745514:HU731 RS16165
gene id: 2745514:HU731_RS16165
uniprot id: A0A9E6T434
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

2745514:HU731 RS12795
gene id: 2745514:HU731_RS12795
uniprot id: A0A9E6T8J9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

2745514:HU731 RS19955
gene id: 2745514:HU731_RS19955
uniprot id: A0A9E6T4Q5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2745514:HU731 RS23160
gene id: 2745514:HU731_RS23160
uniprot id: A0A9E6NCE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

2745514:HU731 RS16610
gene id: 2745514:HU731_RS16610
uniprot id: A0A9E6N9X3
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

2745514:HU731 RS04430
gene id: 2745514:HU731_RS04430
uniprot id: A0A9E6NFV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745514:HU731 RS05825
gene id: 2745514:HU731_RS05825
uniprot id: A0A9E6NG79
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS12785
gene id: 2745514:HU731_RS12785
uniprot id: A0A9E6T8D4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

2745514:HU731 RS01175
gene id: 2745514:HU731_RS01175
uniprot id: A0A9E6NEA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

2745514:HU731 RS19740
gene id: 2745514:HU731_RS19740
uniprot id: A0A9E6NAX5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

2745514:HU731 RS14575
gene id: 2745514:HU731_RS14575
uniprot id: A0A9E6T3M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

2745514:HU731 RS11515
gene id: 2745514:HU731_RS11515
uniprot id: A0A9E6NHW4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS18110
gene id: 2745514:HU731_RS18110
uniprot id: A0A9E6NAU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

2745514:HU731 RS22070
gene id: 2745514:HU731_RS22070
uniprot id: A0A9E6NBR9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745514:HU731 RS10990
gene id: 2745514:HU731_RS10990
uniprot id: A0A9E6NIM9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

2745514:HU731 RS05060
gene id: 2745514:HU731_RS05060
uniprot id: A0A9E6NFM3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

2745514:HU731 RS17980
gene id: 2745514:HU731_RS17980
uniprot id: A0A9E6T4D6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

2745514:HU731 RS20445
gene id: 2745514:HU731_RS20445
uniprot id: A0A9E6T4W2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

2745514:HU731 RS21360
gene id: 2745514:HU731_RS21360
uniprot id: A0A9E6NBS5
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

2745514:HU731 RS15085
gene id: 2745514:HU731_RS15085
uniprot id: A0A9E6N9X9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745514:HU731 RS14270
gene id: 2745514:HU731_RS14270
uniprot id: A0A9E6N9B0
names: Similarity
messages: Belongs to the UPF0166 family.

2745514:HU731 RS17725
gene id: 2745514:HU731_RS17725
uniprot id: A0A9E6NAE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

2745514:HU731 RS12720
gene id: 2745514:HU731_RS12720
uniprot id: A0A9E6T8J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2745514:HU731 RS02050
gene id: 2745514:HU731_RS02050
uniprot id: A0A9E6T6I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

2745514:HU731 RS06890
gene id: 2745514:HU731_RS06890
uniprot id: A0A9E6NH56
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

2745514:HU731 RS20150
gene id: 2745514:HU731_RS20150
uniprot id: A0A9E6NB13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745514:HU731 RS10495
gene id: 2745514:HU731_RS10495
uniprot id: A0A9E6T808
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

2745514:HU731 RS07200
gene id: 2745514:HU731_RS07200
uniprot id: A0A9E6NG84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

2745514:HU731 RS09450
gene id: 2745514:HU731_RS09450
uniprot id: A0A9E6T7P8
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

2745514:HU731 RS14910
gene id: 2745514:HU731_RS14910
uniprot id: A0A9E6T3R4
names: Similarity
messages: Belongs to the UPF0178 family.

2745514:HU731 RS01200
gene id: 2745514:HU731_RS01200
uniprot id: A0A9E6T6D3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

2745514:HU731 RS09015
gene id: 2745514:HU731_RS09015
uniprot id: A0A9E6NHB2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

2745514:HU731 RS07575
gene id: 2745514:HU731_RS07575
uniprot id: A0A9E6NGW6
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

2745514:HU731 RS18515
gene id: 2745514:HU731_RS18515
uniprot id: A0A9E6T4C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

2745514:HU731 RS04440
gene id: 2745514:HU731_RS04440
uniprot id: A0A9E6T6Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745514:HU731 RS08755
gene id: 2745514:HU731_RS08755
uniprot id: A0A9E6T7Q5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2745514:HU731 RS25055
gene id: 2745514:HU731_RS25055
uniprot id: A0A9E6T5J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

2745514:HU731 RS11490
gene id: 2745514:HU731_RS11490
uniprot id: A0A9E6NIT2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS16620
gene id: 2745514:HU731_RS16620
uniprot id: A0A9E6NA19
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

2745514:HU731 RS24495
gene id: 2745514:HU731_RS24495
uniprot id: A0A9E6NCT3
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

2745514:HU731 RS15875
gene id: 2745514:HU731_RS15875
uniprot id: A0A9E6NA79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS11935
gene id: 2745514:HU731_RS11935
uniprot id: A0A9E6T8A2
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

2745514:HU731 RS10045
gene id: 2745514:HU731_RS10045
uniprot id: A0A9E6NHM4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

2745514:HU731 RS24545
gene id: 2745514:HU731_RS24545
uniprot id: A0A9E6NDD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS17125
gene id: 2745514:HU731_RS17125
uniprot id: A0A9E6NA12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

2745514:HU731 RS12610
gene id: 2745514:HU731_RS12610
uniprot id: A0A9E6NI98
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2745514:HU731 RS27930
gene id: 2745514:HU731_RS27930
uniprot id: A0A9E6NDS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

2745514:HU731 RS14595
gene id: 2745514:HU731_RS14595
uniprot id: A0A9E6N9S3
names: Similarity
messages: Belongs to the glutamine synthetase family.

2745514:HU731 RS15470
gene id: 2745514:HU731_RS15470
uniprot id: A0A9E6N9H6
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

2745514:HU731 RS07945
gene id: 2745514:HU731_RS07945
uniprot id: A0A9E6NGM3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

2745514:HU731 RS01085
gene id: 2745514:HU731_RS01085
uniprot id: A0A9E6NF75
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS08990
gene id: 2745514:HU731_RS08990
uniprot id: A0A9E6NHZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2745514:HU731 RS03420
gene id: 2745514:HU731_RS03420
uniprot id: A0A9E6NFZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

2745514:HU731 RS16020
gene id: 2745514:HU731_RS16020
uniprot id: A0A9E6N9Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

2745514:HU731 RS04365
gene id: 2745514:HU731_RS04365
uniprot id: A0A9E6T6X9
names: Similarity
messages: Belongs to the ClpA/ClpB family.

2745514:HU731 RS18640
gene id: 2745514:HU731_RS18640
uniprot id: A0A9E6NAH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

2745514:HU731 RS10465
gene id: 2745514:HU731_RS10465
uniprot id: A0A9E6NHI9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

2745514:HU731 RS15520
gene id: 2745514:HU731_RS15520
uniprot id: A0A9E6T3Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

2745514:HU731 RS24320
gene id: 2745514:HU731_RS24320
uniprot id: A0A9E6NDA5
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS21725
gene id: 2745514:HU731_RS21725
uniprot id: A0A9E6NCB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS09920
gene id: 2745514:HU731_RS09920
uniprot id: A0A9E6T811
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

2745514:HU731 RS10515
gene id: 2745514:HU731_RS10515
uniprot id: A0A9E6NHK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

2745514:HU731 RS13955
gene id: 2745514:HU731_RS13955
uniprot id: A0A9E6NIN4
names: Similarity
messages: Belongs to the YggT family.

2745514:HU731 RS04700
gene id: 2745514:HU731_RS04700
uniprot id: A0A9E6NFB5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745514:HU731 RS21590
gene id: 2745514:HU731_RS21590
uniprot id: A0A9E6NBV2
names: Similarity
messages: Belongs to the glutamate synthase family.

2745514:HU731 RS24580
gene id: 2745514:HU731_RS24580
uniprot id: A0A9E6NCP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

2745514:HU731 RS18560
gene id: 2745514:HU731_RS18560
uniprot id: A0A9E6NAJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

2745514:HU731 RS07210
gene id: 2745514:HU731_RS07210
uniprot id: A0A9E6NHA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

2745514:HU731 RS10290
gene id: 2745514:HU731_RS10290
uniprot id: A0A9E6NIE7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

2745514:HU731 RS26640
gene id: 2745514:HU731_RS26640
uniprot id: A0A9E6NDB8
names: Similarity
messages: Belongs to the type IA topoisomerase family.

2745514:HU731 RS16240
gene id: 2745514:HU731_RS16240
uniprot id: A0A9E6T440
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS11175
gene id: 2745514:HU731_RS11175
uniprot id: A0A9E6NHS8
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS16040
gene id: 2745514:HU731_RS16040
uniprot id: A0A9E6N9R0
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

2745514:HU731 RS15015
gene id: 2745514:HU731_RS15015
uniprot id: A0A9E6N988
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

2745514:HU731 RS07005
gene id: 2745514:HU731_RS07005
uniprot id: A0A9E6NGP8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745514:HU731 RS08180
gene id: 2745514:HU731_RS08180
uniprot id: A0A9E6NGQ5
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

2745514:HU731 RS12625
gene id: 2745514:HU731_RS12625
uniprot id: A0A9E6NIL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2745514:HU731 RS12190
gene id: 2745514:HU731_RS12190
uniprot id: A0A9E6NIT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

2745514:HU731 RS09985
gene id: 2745514:HU731_RS09985
uniprot id: A0A9E6NHC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

2745514:HU731 RS22415
gene id: 2745514:HU731_RS22415
uniprot id: A0A9E6T547
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

2745514:HU731 RS08995
gene id: 2745514:HU731_RS08995
uniprot id: A0A9E6NH08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2745514:HU731 RS12155
gene id: 2745514:HU731_RS12155
uniprot id: A0A9E6T8F5
names: Similarity
messages: Belongs to the UPF0250 family.

2745514:HU731 RS11425
gene id: 2745514:HU731_RS11425
uniprot id: A0A9E6NHV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

2745514:HU731 RS11920
gene id: 2745514:HU731_RS11920
uniprot id: A0A9E6T887
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS05230
gene id: 2745514:HU731_RS05230
uniprot id: A0A9E6NFP3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS05765
gene id: 2745514:HU731_RS05765
uniprot id: A0A9E6NGA1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2745514:HU731 RS04240
gene id: 2745514:HU731_RS04240
uniprot id: A0A9E6NGB4
names: Similarity
messages: Belongs to the WrbA family.

2745514:HU731 RS17365
gene id: 2745514:HU731_RS17365
uniprot id: A0A9E6NAG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745514:HU731 RS13525
gene id: 2745514:HU731_RS13525
uniprot id: A0A9E6NII9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS09870
gene id: 2745514:HU731_RS09870
uniprot id: A0A9E6NH82
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

2745514:HU731 RS19835
gene id: 2745514:HU731_RS19835
uniprot id: A0A9E6NAZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2745514:HU731 RS11800
gene id: 2745514:HU731_RS11800
uniprot id: A0A9E6NJ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS17975
gene id: 2745514:HU731_RS17975
uniprot id: A0A9E6T492
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

2745514:HU731 RS17700
gene id: 2745514:HU731_RS17700
uniprot id: A0A9E6NA82
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS08230
gene id: 2745514:HU731_RS08230
uniprot id: A0A9E6NGR0
names: Similarity
messages: Belongs to the citrate synthase family.

2745514:HU731 RS04185
gene id: 2745514:HU731_RS04185
uniprot id: A0A9E6NFC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

2745514:HU731 RS22095
gene id: 2745514:HU731_RS22095
uniprot id: A0A9E6T508
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

2745514:HU731 RS10910
gene id: 2745514:HU731_RS10910
uniprot id: A0A9E6NIJ0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2745514:HU731 RS24805
gene id: 2745514:HU731_RS24805
uniprot id: A0A9E6NCS5
names: Function
names: Similarity
messages: Belongs to the ribose 1,5-bisphosphokinase family.
messages: Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).

2745514:HU731 RS10320
gene id: 2745514:HU731_RS10320
uniprot id: A0A9E6T836
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

2745514:HU731 RS13900
gene id: 2745514:HU731_RS13900
uniprot id: A0A9E6NJM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

2745514:HU731 RS12775
gene id: 2745514:HU731_RS12775
uniprot id: A0A9E6NIN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2745514:HU731 RS23650
gene id: 2745514:HU731_RS23650
uniprot id: A0A9E6T5B1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

2745514:HU731 RS11565
gene id: 2745514:HU731_RS11565
uniprot id: A0A9E6NIZ3
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

2745514:HU731 RS12175
gene id: 2745514:HU731_RS12175
uniprot id: A0A9E6T8W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

2745514:HU731 RS01090
gene id: 2745514:HU731_RS01090
uniprot id: A0A9E6NIU8
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

2745514:HU731 RS16015
gene id: 2745514:HU731_RS16015
uniprot id: A0A9E6T409
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

2745514:HU731 RS19070
gene id: 2745514:HU731_RS19070
uniprot id: A0A9E6T4K5
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

2745514:HU731 RS21815
gene id: 2745514:HU731_RS21815
uniprot id: A0A9E6NC46
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

2745514:HU731 RS26160
gene id: 2745514:HU731_RS26160
uniprot id: A0A9E6T5T4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745514:HU731 RS14695
gene id: 2745514:HU731_RS14695
uniprot id: A0A9E6N9J0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

2745514:HU731 RS24965
gene id: 2745514:HU731_RS24965
uniprot id: A0A9E6NDC5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

2745514:HU731 RS15185
gene id: 2745514:HU731_RS15185
uniprot id: A0A9E6N9P1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2745514:HU731 RS22210
gene id: 2745514:HU731_RS22210
uniprot id: A0A9E6NCI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

2745514:HU731 RS17405
gene id: 2745514:HU731_RS17405
uniprot id: A0A9E6T458
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

2745514:HU731 RS02795
gene id: 2745514:HU731_RS02795
uniprot id: A0A9E6NEV1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

2745514:HU731 RS12310
gene id: 2745514:HU731_RS12310
uniprot id: A0A9E6T8G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

2745514:HU731 RS18930
gene id: 2745514:HU731_RS18930
uniprot id: A0A9E6NBB1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

2745514:HU731 RS09160
gene id: 2745514:HU731_RS09160
uniprot id: A0A9E6NI08
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745514:HU731 RS10635
gene id: 2745514:HU731_RS10635
uniprot id: A0A9E6T807
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

2745514:HU731 RS27505
gene id: 2745514:HU731_RS27505
uniprot id: A0A9E6T610
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

2745514:HU731 RS17060
gene id: 2745514:HU731_RS17060
uniprot id: A0A9E6NA80
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2745514:HU731 RS21265
gene id: 2745514:HU731_RS21265
uniprot id: A0A9E6NC75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS23205
gene id: 2745514:HU731_RS23205
uniprot id: A0A9E6NC23
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homodimer.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

2745514:HU731 RS12695
gene id: 2745514:HU731_RS12695
uniprot id: A0A9E6NIA4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2745514:HU731 RS22950
gene id: 2745514:HU731_RS22950
uniprot id: A0A9E6T567
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

2745514:HU731 RS05260
gene id: 2745514:HU731_RS05260
uniprot id: A0A9E6T6Z7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745514:HU731 RS22435
gene id: 2745514:HU731_RS22435
uniprot id: A0A9E6NBT2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745514:HU731 RS12080
gene id: 2745514:HU731_RS12080
uniprot id: A0A9E6T895
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

2745514:HU731 RS17765
gene id: 2745514:HU731_RS17765
uniprot id: A0A9E6NAS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

2745514:HU731 RS19060
gene id: 2745514:HU731_RS19060
uniprot id: A0A9E6T4I5
names: Similarity
messages: Belongs to the GARS family.

2745514:HU731 RS09395
gene id: 2745514:HU731_RS09395
uniprot id: A0A9E6NI39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LysR transcriptional regulatory family.
messages: Controls the transcription of genes involved in arginine and lysine metabolism.
messages: Homodimer.

2745514:HU731 RS18860
gene id: 2745514:HU731_RS18860
uniprot id: A0A9E6NAL8
names: Similarity
messages: Belongs to the bacterioferritin family.

2745514:HU731 RS18675
gene id: 2745514:HU731_RS18675
uniprot id: A0A9E6T4I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

2745514:HU731 RS12770
gene id: 2745514:HU731_RS12770
uniprot id: A0A9E6NIB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2745514:HU731 RS25450
gene id: 2745514:HU731_RS25450
uniprot id: A0A9E6NCU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745514:HU731 RS07795
gene id: 2745514:HU731_RS07795
uniprot id: A0A9E6NGK7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745514:HU731 RS24195
gene id: 2745514:HU731_RS24195
uniprot id: A0A9E6NCE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

2745514:HU731 RS08065
gene id: 2745514:HU731_RS08065
uniprot id: A0A9E6NHK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

2745514:HU731 RS20835
gene id: 2745514:HU731_RS20835
uniprot id: A0A9E6NBV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

2745514:HU731 RS20280
gene id: 2745514:HU731_RS20280
uniprot id: A0A9E6T4S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS13720
gene id: 2745514:HU731_RS13720
uniprot id: A0A9E6T8Q5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

2745514:HU731 RS22365
gene id: 2745514:HU731_RS22365
uniprot id: A0A9E6NC40
names: Similarity
messages: Belongs to the Skp family.

2745514:HU731 RS08150
gene id: 2745514:HU731_RS08150
uniprot id: A0A9E6NHM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

2745514:HU731 RS24530
gene id: 2745514:HU731_RS24530
uniprot id: A0A9E6T5M5
names: Similarity
messages: Belongs to the OsmC/Ohr family.

2745514:HU731 RS12735
gene id: 2745514:HU731_RS12735
uniprot id: A0A9E6NIZ0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2745514:HU731 RS16005
gene id: 2745514:HU731_RS16005
uniprot id: A0A9E6T405
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

2745514:HU731 RS18135
gene id: 2745514:HU731_RS18135
uniprot id: A0A9E6T4E7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS06215
gene id: 2745514:HU731_RS06215
uniprot id: A0A9E6T7D2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745514:HU731 RS04315
gene id: 2745514:HU731_RS04315
uniprot id: A0A9E6NGC3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

2745514:HU731 RS10845
gene id: 2745514:HU731_RS10845
uniprot id: A0A9E6NHW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

2745514:HU731 RS12065
gene id: 2745514:HU731_RS12065
uniprot id: A0A9E6NI27
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

2745514:HU731 RS09975
gene id: 2745514:HU731_RS09975
uniprot id: A0A9E6NHB3
names: Similarity
messages: Belongs to the pyruvate kinase family.

2745514:HU731 RS23585
gene id: 2745514:HU731_RS23585
uniprot id: A0A9E6T5H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

2745514:HU731 RS11030
gene id: 2745514:HU731_RS11030
uniprot id: A0A9E6NI40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

2745514:HU731 RS23100
gene id: 2745514:HU731_RS23100
uniprot id: A0A9E6T5D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

2745514:HU731 RS12880
gene id: 2745514:HU731_RS12880
uniprot id: A0A9E6NIC9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

2745514:HU731 RS28015
gene id: 2745514:HU731_RS28015
uniprot id: A0A9E6NDT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS18615
gene id: 2745514:HU731_RS18615
uniprot id: A0A9E6NB45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

2745514:HU731 RS27140
gene id: 2745514:HU731_RS27140
uniprot id: A0A9E6NDS3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2745514:HU731 RS27355
gene id: 2745514:HU731_RS27355
uniprot id: A0A9E6NDF5
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS17740
gene id: 2745514:HU731_RS17740
uniprot id: A0A9E6T4C8
names: Similarity
messages: Belongs to the peptidase S41A family.

2745514:HU731 RS13615
gene id: 2745514:HU731_RS13615
uniprot id: A0A9E6T8I4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

2745514:HU731 RS12680
gene id: 2745514:HU731_RS12680
uniprot id: A0A9E6NII0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2745514:HU731 RS16035
gene id: 2745514:HU731_RS16035
uniprot id: A0A9E6N9P7
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS25445
gene id: 2745514:HU731_RS25445
uniprot id: A0A9E6NDU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745514:HU731 RS21415
gene id: 2745514:HU731_RS21415
uniprot id: A0A9E6NBC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

2745514:HU731 RS20515
gene id: 2745514:HU731_RS20515
uniprot id: A0A9E6NBP8
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

2745514:HU731 RS02280
gene id: 2745514:HU731_RS02280
uniprot id: A0A9E6T8J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS20665
gene id: 2745514:HU731_RS20665
uniprot id: A0A9E6NBT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

2745514:HU731 RS09275
gene id: 2745514:HU731_RS09275
uniprot id: A0A9E6T7X1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

2745514:HU731 RS17710
gene id: 2745514:HU731_RS17710
uniprot id: A0A9E6NAJ7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

2745514:HU731 RS11580
gene id: 2745514:HU731_RS11580
uniprot id: A0A9E6NI43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

2745514:HU731 RS01600
gene id: 2745514:HU731_RS01600
uniprot id: A0A9E6T6F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

2745514:HU731 RS15055
gene id: 2745514:HU731_RS15055
uniprot id: A0A9E6T3X5
names: Similarity
messages: Belongs to the UPF0047 family.

2745514:HU731 RS07430
gene id: 2745514:HU731_RS07430
uniprot id: A0A9E6T7L7
names: Subcellular Location Annotation
messages: Cell inner membrane

2745514:HU731 RS22455
gene id: 2745514:HU731_RS22455
uniprot id: A0A9E6NBW4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

2745514:HU731 RS21435
gene id: 2745514:HU731_RS21435
uniprot id: A0A9E6NBZ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

2745514:HU731 RS26935
gene id: 2745514:HU731_RS26935
uniprot id: A0A9E6T5T5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745514:HU731 RS25410
gene id: 2745514:HU731_RS25410
uniprot id: A0A9E6T5S2
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS15780
gene id: 2745514:HU731_RS15780
uniprot id: A0A9E6T3W8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745514:HU731 RS22670
gene id: 2745514:HU731_RS22670
uniprot id: A0A9E6NCQ1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS18280
gene id: 2745514:HU731_RS18280
uniprot id: A0A9E6T4A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
messages: Cell membrane
messages: K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.

2745514:HU731 RS17260
gene id: 2745514:HU731_RS17260
uniprot id: A0A9E6NA38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS24970
gene id: 2745514:HU731_RS24970
uniprot id: A0A9E6T5P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

2745514:HU731 RS06025
gene id: 2745514:HU731_RS06025
uniprot id: A0A9E6NFY2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

2745514:HU731 RS07715
gene id: 2745514:HU731_RS07715
uniprot id: A0A9E6NGW2
names: Similarity
messages: Belongs to the DEAD box helicase family.

2745514:HU731 RS01340
gene id: 2745514:HU731_RS01340
uniprot id: A0A9E6NEY9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745514:HU731 RS18695
gene id: 2745514:HU731_RS18695
uniprot id: A0A9E6NAG9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

2745514:HU731 RS06975
gene id: 2745514:HU731_RS06975
uniprot id: A0A9E6NGA0
names: Similarity
messages: Belongs to the Lgt family.

2745514:HU731 RS09280
gene id: 2745514:HU731_RS09280
uniprot id: A0A9E6T7S5
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS24165
gene id: 2745514:HU731_RS24165
uniprot id: A0A9E6ND88
names: Caution
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS00350
gene id: 2745514:HU731_RS00350
uniprot id: A0A9E6T673
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS06710
gene id: 2745514:HU731_RS06710
uniprot id: A0A9E6T7B2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2745514:HU731 RS17885
gene id: 2745514:HU731_RS17885
uniprot id: A0A9E6T4C6
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS15550
gene id: 2745514:HU731_RS15550
uniprot id: A0A9E6T3V4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

2745514:HU731 RS22475
gene id: 2745514:HU731_RS22475
uniprot id: A0A9E6T596
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

2745514:HU731 RS13205
gene id: 2745514:HU731_RS13205
uniprot id: A0A9E6NIF9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

2745514:HU731 RS17080
gene id: 2745514:HU731_RS17080
uniprot id: A0A9E6T469
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS11355
gene id: 2745514:HU731_RS11355
uniprot id: A0A9E6NI78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

2745514:HU731 RS15220
gene id: 2745514:HU731_RS15220
uniprot id: A0A9E6T3V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

2745514:HU731 RS23410
gene id: 2745514:HU731_RS23410
uniprot id: A0A9E6T5E6
names: Similarity
messages: Belongs to the UPF0260 family.

2745514:HU731 RS11430
gene id: 2745514:HU731_RS11430
uniprot id: A0A9E6NI89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2745514:HU731 RS17780
gene id: 2745514:HU731_RS17780
uniprot id: A0A9E6NAE9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

2745514:HU731 RS10460
gene id: 2745514:HU731_RS10460
uniprot id: A0A9E6NHV2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

2745514:HU731 RS26715
gene id: 2745514:HU731_RS26715
uniprot id: A0A9E6NE83
names: Similarity
messages: Belongs to the MQO family.

2745514:HU731 RS07220
gene id: 2745514:HU731_RS07220
uniprot id: A0A9E6NHB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2745514:HU731 RS02285
gene id: 2745514:HU731_RS02285
uniprot id: A0A9E6T6K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

2745514:HU731 RS05580
gene id: 2745514:HU731_RS05580
uniprot id: A0A9E6T7A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS04945
gene id: 2745514:HU731_RS04945
uniprot id: A0A9E6T758
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS13025
gene id: 2745514:HU731_RS13025
uniprot id: A0A9E6NJB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

2745514:HU731 RS18800
gene id: 2745514:HU731_RS18800
uniprot id: A0A9E6NAJ2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2745514:HU731 RS01335
gene id: 2745514:HU731_RS01335
uniprot id: A0A9E6NEE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

2745514:HU731 RS16370
gene id: 2745514:HU731_RS16370
uniprot id: A0A9E6N9U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

2745514:HU731 RS09340
gene id: 2745514:HU731_RS09340
uniprot id: A0A9E6NHF2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS19700
gene id: 2745514:HU731_RS19700
uniprot id: A0A9E6T4P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

2745514:HU731 RS24155
gene id: 2745514:HU731_RS24155
uniprot id: A0A9E6T5G4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

2745514:HU731 RS24125
gene id: 2745514:HU731_RS24125
uniprot id: A0A9E6NCJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745514:HU731 RS25880
gene id: 2745514:HU731_RS25880
uniprot id: A0A9E6NDX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2745514:HU731 RS08515
gene id: 2745514:HU731_RS08515
uniprot id: A0A9E6T7M6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS12085
gene id: 2745514:HU731_RS12085
uniprot id: A0A9E6T866
names: Similarity
messages: Belongs to the PhoH family.

2745514:HU731 RS10795
gene id: 2745514:HU731_RS10795
uniprot id: A0A9E6T817
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

2745514:HU731 RS12715
gene id: 2745514:HU731_RS12715
uniprot id: A0A9E6T8A6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2745514:HU731 RS16255
gene id: 2745514:HU731_RS16255
uniprot id: A0A9E6T423
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

2745514:HU731 RS03415
gene id: 2745514:HU731_RS03415
uniprot id: A0A9E6NEZ3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS23425
gene id: 2745514:HU731_RS23425
uniprot id: A0A9E6T5G6
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

2745514:HU731 RS18195
gene id: 2745514:HU731_RS18195
uniprot id: A0A9E6T4F9
names: Subunit
messages: Monomer.

2745514:HU731 RS07215
gene id: 2745514:HU731_RS07215
uniprot id: A0A9E6NGD1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

2745514:HU731 RS10180
gene id: 2745514:HU731_RS10180
uniprot id: A0A9E6NHC2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

2745514:HU731 RS17530
gene id: 2745514:HU731_RS17530
uniprot id: A0A9E6NA70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

2745514:HU731 RS11710
gene id: 2745514:HU731_RS11710
uniprot id: A0A9E6T881
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS22180
gene id: 2745514:HU731_RS22180
uniprot id: A0A9E6T532
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2745514:HU731 RS24960
gene id: 2745514:HU731_RS24960
uniprot id: A0A9E6NCU5
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: The active site is a redox-active disulfide bond.

2745514:HU731 RS04575
gene id: 2745514:HU731_RS04575
uniprot id: A0A9E6NFS9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

2745514:HU731 RS09795
gene id: 2745514:HU731_RS09795
uniprot id: A0A9E6NH72
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

2745514:HU731 RS24525
gene id: 2745514:HU731_RS24525
uniprot id: A0A9E6T5F1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS13910
gene id: 2745514:HU731_RS13910
uniprot id: A0A9E6NJ62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

2745514:HU731 RS17105
gene id: 2745514:HU731_RS17105
uniprot id: A0A9E6NAL3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

2745514:HU731 RS11520
gene id: 2745514:HU731_RS11520
uniprot id: A0A9E6NI96
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

2745514:HU731 RS26135
gene id: 2745514:HU731_RS26135
uniprot id: A0A9E6ND56
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2745514:HU731 RS10250
gene id: 2745514:HU731_RS10250
uniprot id: A0A9E6T7Y3
names: Similarity
messages: Belongs to the threonine synthase family.

2745514:HU731 RS24170
gene id: 2745514:HU731_RS24170
uniprot id: A0A9E6NDE2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

2745514:HU731 RS20950
gene id: 2745514:HU731_RS20950
uniprot id: A0A9E6NC16
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

2745514:HU731 RS15190
gene id: 2745514:HU731_RS15190
uniprot id: A0A9E6N9B7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2745514:HU731 RS13055
gene id: 2745514:HU731_RS13055
uniprot id: A0A9E6T8L4
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

2745514:HU731 RS12765
gene id: 2745514:HU731_RS12765
uniprot id: A0A9E6NIV2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2745514:HU731 RS16415
gene id: 2745514:HU731_RS16415
uniprot id: A0A9E6NAA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745514:HU731 RS11040
gene id: 2745514:HU731_RS11040
uniprot id: A0A9E6T832
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2745514:HU731 RS09855
gene id: 2745514:HU731_RS09855
uniprot id: A0A9E6T7S2
names: Similarity
messages: Belongs to the UPF0234 family.

2745514:HU731 RS00960
gene id: 2745514:HU731_RS00960
uniprot id: A0A9E6T6B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

2745514:HU731 RS11540
gene id: 2745514:HU731_RS11540
uniprot id: A0A9E6T8C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

2745514:HU731 RS25975
gene id: 2745514:HU731_RS25975
uniprot id: A0A9E6NCZ8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

2745514:HU731 RS19450
gene id: 2745514:HU731_RS19450
uniprot id: A0A9E6NAZ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS00320
gene id: 2745514:HU731_RS00320
uniprot id: A0A9E6NEK8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

2745514:HU731 RS18295
gene id: 2745514:HU731_RS18295
uniprot id: A0A9E6NAY4
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

2745514:HU731 RS22330
gene id: 2745514:HU731_RS22330
uniprot id: A0A9E6T582
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS20130
gene id: 2745514:HU731_RS20130
uniprot id: A0A9E6T4R3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

2745514:HU731 RS23200
gene id: 2745514:HU731_RS23200
uniprot id: A0A9E6T5A6
names: Subcellular Location Annotation
messages: Cytoplasm

2745514:HU731 RS12630
gene id: 2745514:HU731_RS12630
uniprot id: A0A9E6T8I7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2745514:HU731 RS12510
gene id: 2745514:HU731_RS12510
uniprot id: A0A9E6NIW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

2745514:HU731 RS11795
gene id: 2745514:HU731_RS11795
uniprot id: A0A9E6NIR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

2745514:HU731 RS14020
gene id: 2745514:HU731_RS14020
uniprot id: A0A9E6T8I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

2745514:HU731 RS02305
gene id: 2745514:HU731_RS02305
uniprot id: A0A9E6NEL0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

2745514:HU731 RS14950
gene id: 2745514:HU731_RS14950
uniprot id: A0A9E6N969
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

2745514:HU731 RS27160
gene id: 2745514:HU731_RS27160
uniprot id: A0A9E6NE27
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745514:HU731 RS13375
gene id: 2745514:HU731_RS13375
uniprot id: A0A9E6T8G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

2745514:HU731 RS08655
gene id: 2745514:HU731_RS08655
uniprot id: A0A9E6NHA8
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

2745514:HU731 RS10585
gene id: 2745514:HU731_RS10585
uniprot id: A0A9E6NII4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

2745514:HU731 RS20525
gene id: 2745514:HU731_RS20525
uniprot id: A0A9E6T4T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.

2745514:HU731 RS26120
gene id: 2745514:HU731_RS26120
uniprot id: A0A9E6ND62
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS02940
gene id: 2745514:HU731_RS02940
uniprot id: A0A9E6NFV4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2745514:HU731 RS06640
gene id: 2745514:HU731_RS06640
uniprot id: A0A9E6T775
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

2745514:HU731 RS15500
gene id: 2745514:HU731_RS15500
uniprot id: A0A9E6N9I5
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

2745514:HU731 RS08505
gene id: 2745514:HU731_RS08505
uniprot id: A0A9E6NH91
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2745514:HU731 RS15205
gene id: 2745514:HU731_RS15205
uniprot id: A0A9E6N9I3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS21850
gene id: 2745514:HU731_RS21850
uniprot id: A0A9E6T513
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2745514:HU731 RS20545
gene id: 2745514:HU731_RS20545
uniprot id: A0A9E6NB22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

2745514:HU731 RS01790
gene id: 2745514:HU731_RS01790
uniprot id: A0A9E6NED3
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

2745514:HU731 RS04705
gene id: 2745514:HU731_RS04705
uniprot id: A0A9E6NGF3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745514:HU731 RS14650
gene id: 2745514:HU731_RS14650
uniprot id: A0A9E6T3R9
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

2745514:HU731 RS23665
gene id: 2745514:HU731_RS23665
uniprot id: A0A9E6T5D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

2745514:HU731 RS26995
gene id: 2745514:HU731_RS26995
uniprot id: A0A9E6NDA4
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

2745514:HU731 RS05970
gene id: 2745514:HU731_RS05970
uniprot id: A0A9E6T7C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

2745514:HU731 RS14825
gene id: 2745514:HU731_RS14825
uniprot id: A0A9E6T3P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

2745514:HU731 RS06100
gene id: 2745514:HU731_RS06100
uniprot id: A0A9E6NFZ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

2745514:HU731 RS15750
gene id: 2745514:HU731_RS15750
uniprot id: A0A9E6N9Q5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2745514:HU731 RS26780
gene id: 2745514:HU731_RS26780
uniprot id: A0A9E6NE61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

2745514:HU731 RS17800
gene id: 2745514:HU731_RS17800
uniprot id: A0A9E6NAF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS17100
gene id: 2745514:HU731_RS17100
uniprot id: A0A9E6NAJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

2745514:HU731 RS07615
gene id: 2745514:HU731_RS07615
uniprot id: A0A9E6NHF6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

2745514:HU731 RS04265
gene id: 2745514:HU731_RS04265
uniprot id: A0A9E6NFT6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

2745514:HU731 RS13135
gene id: 2745514:HU731_RS13135
uniprot id: A0A9E6NIQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PqqD family.
messages: Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
messages: Monomer. Interacts with PqqE.

2745514:HU731 RS12760
gene id: 2745514:HU731_RS12760
uniprot id: A0A9E6NIB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2745514:HU731 RS11495
gene id: 2745514:HU731_RS11495
uniprot id: A0A9E6NI33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

2745514:HU731 RS06950
gene id: 2745514:HU731_RS06950
uniprot id: A0A9E6T7I6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2745514:HU731 RS12885
gene id: 2745514:HU731_RS12885
uniprot id: A0A9E6NIW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

2745514:HU731 RS19900
gene id: 2745514:HU731_RS19900
uniprot id: A0A9E6NBH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

2745514:HU731 RS09005
gene id: 2745514:HU731_RS09005
uniprot id: A0A9E6NH97
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

2745514:HU731 RS20005
gene id: 2745514:HU731_RS20005
uniprot id: A0A9E6NBA7
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS25110
gene id: 2745514:HU731_RS25110
uniprot id: A0A9E6NCW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

2745514:HU731 RS24935
gene id: 2745514:HU731_RS24935
uniprot id: A0A9E6NCM3
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

2745514:HU731 RS13960
gene id: 2745514:HU731_RS13960
uniprot id: A0A9E6NJG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

2745514:HU731 RS18620
gene id: 2745514:HU731_RS18620
uniprot id: A0A9E6NB95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

2745514:HU731 RS13650
gene id: 2745514:HU731_RS13650
uniprot id: A0A9E6NIQ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS22460
gene id: 2745514:HU731_RS22460
uniprot id: A0A9E6NBY2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

2745514:HU731 RS08965
gene id: 2745514:HU731_RS08965
uniprot id: A0A9E6T7W2
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

2745514:HU731 RS09285
gene id: 2745514:HU731_RS09285
uniprot id: A0A9E6T7N8
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

2745514:HU731 RS27445
gene id: 2745514:HU731_RS27445
uniprot id: A0A9E6NEH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rubredoxin family.
messages: Cytoplasm

2745514:HU731 RS06915
gene id: 2745514:HU731_RS06915
uniprot id: A0A9E6NG87
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

2745514:HU731 RS25285
gene id: 2745514:HU731_RS25285
uniprot id: A0A9E6NDR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

2745514:HU731 RS24360
gene id: 2745514:HU731_RS24360
uniprot id: A0A9E6ND39
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS04325
gene id: 2745514:HU731_RS04325
uniprot id: A0A9E6NF94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

2745514:HU731 RS07375
gene id: 2745514:HU731_RS07375
uniprot id: A0A9E6NHC3
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

2745514:HU731 RS12730
gene id: 2745514:HU731_RS12730
uniprot id: A0A9E6NIA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

2745514:HU731 RS20830
gene id: 2745514:HU731_RS20830
uniprot id: A0A9E6NBC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

2745514:HU731 RS27180
gene id: 2745514:HU731_RS27180
uniprot id: A0A9E6T636
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745514:HU731 RS24860
gene id: 2745514:HU731_RS24860
uniprot id: A0A9E6NCL7
names: Similarity
messages: Belongs to the hyi family.

2745514:HU731 RS23245
gene id: 2745514:HU731_RS23245
uniprot id: A0A9E6NC66
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS09455
gene id: 2745514:HU731_RS09455
uniprot id: A0A9E6T7Z3
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS19050
gene id: 2745514:HU731_RS19050
uniprot id: A0A9E6T4M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS12960
gene id: 2745514:HU731_RS12960
uniprot id: A0A9E6NIX0
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

2745514:HU731 RS12475
gene id: 2745514:HU731_RS12475
uniprot id: A0A9E6NIK0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

2745514:HU731 RS20900
gene id: 2745514:HU731_RS20900
uniprot id: A0A9E6NBC9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745514:HU731 RS27890
gene id: 2745514:HU731_RS27890
uniprot id: A0A9E6T688
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

2745514:HU731 RS19125
gene id: 2745514:HU731_RS19125
uniprot id: A0A9E6T4M8
names: Similarity
messages: Belongs to the SUI1 family.

2745514:HU731 RS08630
gene id: 2745514:HU731_RS08630
uniprot id: A0A9E6NHV1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2745514:HU731 RS16090
gene id: 2745514:HU731_RS16090
uniprot id: A0A9E6T3Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

2745514:HU731 RS09550
gene id: 2745514:HU731_RS09550
uniprot id: A0A9E6NH31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

2745514:HU731 RS27705
gene id: 2745514:HU731_RS27705
uniprot id: A0A9E6NE95
names: Similarity
messages: Belongs to the IlvD/Edd family.

2745514:HU731 RS13895
gene id: 2745514:HU731_RS13895
uniprot id: A0A9E6NIR5
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

2745514:HU731 RS08090
gene id: 2745514:HU731_RS08090
uniprot id: A0A9E6NGP0
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

2745514:HU731 RS14265
gene id: 2745514:HU731_RS14265
uniprot id: A0A9E6N8N1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

2745514:HU731 RS20955
gene id: 2745514:HU731_RS20955
uniprot id: A0A9E6NBB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AlgF family.
messages: Periplasm

2745514:HU731 RS12595
gene id: 2745514:HU731_RS12595
uniprot id: A0A9E6NID9
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

2745514:HU731 RS04450
gene id: 2745514:HU731_RS04450
uniprot id: A0A9E6T737
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

2745514:HU731 RS15745
gene id: 2745514:HU731_RS15745
uniprot id: A0A9E6N9L6
names: Cofactor
messages: Binds 1 zinc ion per subunit.

2745514:HU731 RS18755
gene id: 2745514:HU731_RS18755
uniprot id: A0A9E6T4H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

2745514:HU731 RS19820
gene id: 2745514:HU731_RS19820
uniprot id: A0A9E6NBE0
names: Function
names: Similarity
messages: Belongs to the bacterial renalase family.
messages: Catalyzes the oxidation of the 1,2-dihydro- and 1,6-dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P)+. May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers.

2745514:HU731 RS24020
gene id: 2745514:HU731_RS24020
uniprot id: A0A9E6NDC1
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS07305
gene id: 2745514:HU731_RS07305
uniprot id: A0A9E6NHC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

2745514:HU731 RS19665
gene id: 2745514:HU731_RS19665
uniprot id: A0A9E6NB77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SctL stator family.
messages: Cytoplasm

2745514:HU731 RS06035
gene id: 2745514:HU731_RS06035
uniprot id: A0A9E6NGD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

2745514:HU731 RS17910
gene id: 2745514:HU731_RS17910
uniprot id: A0A9E6NA93
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

2745514:HU731 RS17905
gene id: 2745514:HU731_RS17905
uniprot id: A0A9E6T4D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

2745514:HU731 RS14115
gene id: 2745514:HU731_RS14115
uniprot id: A0A9E6NIU1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS22730
gene id: 2745514:HU731_RS22730
uniprot id: A0A9E6NCQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

2745514:HU731 RS14665
gene id: 2745514:HU731_RS14665
uniprot id: A0A9E6N8Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm

2745514:HU731 RS19950
gene id: 2745514:HU731_RS19950
uniprot id: A0A9E6T4L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

2745514:HU731 RS00675
gene id: 2745514:HU731_RS00675
uniprot id: A0A9E6NE03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

2745514:HU731 RS20235
gene id: 2745514:HU731_RS20235
uniprot id: A0A9E6NBS6
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

2745514:HU731 RS19130
gene id: 2745514:HU731_RS19130
uniprot id: A0A9E6T4L3
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

2745514:HU731 RS16080
gene id: 2745514:HU731_RS16080
uniprot id: A0A9E6T428
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2745514:HU731 RS12685
gene id: 2745514:HU731_RS12685
uniprot id: A0A9E6NIA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2745514:HU731 RS04485
gene id: 2745514:HU731_RS04485
uniprot id: A0A9E6NFR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

2745514:HU731 RS21840
gene id: 2745514:HU731_RS21840
uniprot id: A0A9E6NC67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

2745514:HU731 RS26965
gene id: 2745514:HU731_RS26965
uniprot id: A0A9E6NE87
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

2745514:HU731 RS20765
gene id: 2745514:HU731_RS20765
uniprot id: A0A9E6T4T8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

2745514:HU731 RS20050
gene id: 2745514:HU731_RS20050
uniprot id: A0A9E6T4L5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

2745514:HU731 RS20380
gene id: 2745514:HU731_RS20380
uniprot id: A0A9E6T4S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS14970
gene id: 2745514:HU731_RS14970
uniprot id: A0A9E6N9C0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

2745514:HU731 RS14500
gene id: 2745514:HU731_RS14500
uniprot id: A0A9E6N9K7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

2745514:HU731 RS10530
gene id: 2745514:HU731_RS10530
uniprot id: A0A9E6NHI6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

2745514:HU731 RS20775
gene id: 2745514:HU731_RS20775
uniprot id: A0A9E6T4V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2745514:HU731 RS22665
gene id: 2745514:HU731_RS22665
uniprot id: A0A9E6NBW3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS22575
gene id: 2745514:HU731_RS22575
uniprot id: A0A9E6NBU4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

2745514:HU731 RS07515
gene id: 2745514:HU731_RS07515
uniprot id: A0A9E6T7D0
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

2745514:HU731 RS22315
gene id: 2745514:HU731_RS22315
uniprot id: A0A9E6T585
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2745514:HU731 RS04320
gene id: 2745514:HU731_RS04320
uniprot id: A0A9E6NFP9
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

2745514:HU731 RS18115
gene id: 2745514:HU731_RS18115
uniprot id: A0A9E6T4E1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

2745514:HU731 RS18325
gene id: 2745514:HU731_RS18325
uniprot id: A0A9E6NAE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

2745514:HU731 RS13120
gene id: 2745514:HU731_RS13120
uniprot id: A0A9E6NIZ7
names: Function
names: Similarity
messages: Belongs to the PqqA family.
messages: Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.

2745514:HU731 RS21385
gene id: 2745514:HU731_RS21385
uniprot id: A0A9E6NC19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

2745514:HU731 RS17990
gene id: 2745514:HU731_RS17990
uniprot id: A0A9E6NAU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

2745514:HU731 RS19625
gene id: 2745514:HU731_RS19625
uniprot id: A0A9E6T4L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS12280
gene id: 2745514:HU731_RS12280
uniprot id: A0A9E6NJ32
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS11525
gene id: 2745514:HU731_RS11525
uniprot id: A0A9E6T8B2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

2745514:HU731 RS19035
gene id: 2745514:HU731_RS19035
uniprot id: A0A9E6NAP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the precorrin methyltransferase family.
messages: Homodimer.
messages: Methylates precorrin-2 at the C-20 position to produce precorrin-3A.

2745514:HU731 RS17965
gene id: 2745514:HU731_RS17965
uniprot id: A0A9E6T4E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2745514:HU731 RS08185
gene id: 2745514:HU731_RS08185
uniprot id: A0A9E6NH43
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2745514:HU731 RS16130
gene id: 2745514:HU731_RS16130
uniprot id: A0A9E6N9S0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2745514:HU731 RS12670
gene id: 2745514:HU731_RS12670
uniprot id: A0A9E6NIE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2745514:HU731 RS02160
gene id: 2745514:HU731_RS02160
uniprot id: A0A9E6NEM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

2745514:HU731 RS11290
gene id: 2745514:HU731_RS11290
uniprot id: A0A9E6T849
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

2745514:HU731 RS26975
gene id: 2745514:HU731_RS26975
uniprot id: A0A9E6NDG1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745514:HU731 RS28105
gene id: 2745514:HU731_RS28105
uniprot id: A0A9E6NDV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

2745514:HU731 RS28100
gene id: 2745514:HU731_RS28100
uniprot id: A0A9E6NDN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

2745514:HU731 RS16010
gene id: 2745514:HU731_RS16010
uniprot id: A0A9E6T3Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

2745514:HU731 RS14880
gene id: 2745514:HU731_RS14880
uniprot id: A0A9E6N9C4
names: Similarity
messages: Belongs to the GppA/Ppx family.

2745514:HU731 RS01870
gene id: 2745514:HU731_RS01870
uniprot id: A0A9E6NEM7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

2745514:HU731 RS26970
gene id: 2745514:HU731_RS26970
uniprot id: A0A9E6NEC2
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

2745514:HU731 RS07935
gene id: 2745514:HU731_RS07935
uniprot id: A0A9E6NGM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

2745514:HU731 RS07770
gene id: 2745514:HU731_RS07770
uniprot id: A0A9E6NGJ8
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS12725
gene id: 2745514:HU731_RS12725
uniprot id: A0A9E6T8F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2745514:HU731 RS22655
gene id: 2745514:HU731_RS22655
uniprot id: A0A9E6NCP3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2745514:HU731 RS13385
gene id: 2745514:HU731_RS13385
uniprot id: A0A9E6T8E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
messages: Homotetramer.

2745514:HU731 RS04910
gene id: 2745514:HU731_RS04910
uniprot id: A0A9E6NFV7
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2745514:HU731 RS11475
gene id: 2745514:HU731_RS11475
uniprot id: A0A9E6NIP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

2745514:HU731 RS05745
gene id: 2745514:HU731_RS05745
uniprot id: A0A9E6NG69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2745514:HU731 RS16940
gene id: 2745514:HU731_RS16940
uniprot id: A0A9E6NAH9
names: Function
names: Similarity
messages: Belongs to the CsgG family.
messages: May be involved in the biogenesis of curli organelles.

2745514:HU731 RS05655
gene id: 2745514:HU731_RS05655
uniprot id: A0A9E6NFU2
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

2745514:HU731 RS12940
gene id: 2745514:HU731_RS12940
uniprot id: A0A9E6NIJ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS25000
gene id: 2745514:HU731_RS25000
uniprot id: A0A9E6NDK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

2745514:HU731 RS16070
gene id: 2745514:HU731_RS16070
uniprot id: A0A9E6T417
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

2745514:HU731 RS05200
gene id: 2745514:HU731_RS05200
uniprot id: A0A9E6NFJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS20360
gene id: 2745514:HU731_RS20360
uniprot id: A0A9E6T4V8
names: Similarity
messages: Belongs to the DapA family.

2745514:HU731 RS10145
gene id: 2745514:HU731_RS10145
uniprot id: A0A9E6NHE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

2745514:HU731 RS15430
gene id: 2745514:HU731_RS15430
uniprot id: A0A9E6NJF3
names: Similarity
messages: Belongs to the VgrG protein family.

2745514:HU731 RS04905
gene id: 2745514:HU731_RS04905
uniprot id: A0A9E6NFE6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

2745514:HU731 RS13640
gene id: 2745514:HU731_RS13640
uniprot id: A0A9E6NJC5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

2745514:HU731 RS20535
gene id: 2745514:HU731_RS20535
uniprot id: A0A9E6T4R4
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

2745514:HU731 RS24410
gene id: 2745514:HU731_RS24410
uniprot id: A0A9E6NDD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

2745514:HU731 RS12740
gene id: 2745514:HU731_RS12740
uniprot id: A0A9E6NJE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2745514:HU731 RS02585
gene id: 2745514:HU731_RS02585
uniprot id: A0A9E6NFB1
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS00160
gene id: 2745514:HU731_RS00160
uniprot id: A0A9E6NDR6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745514:HU731 RS20530
gene id: 2745514:HU731_RS20530
uniprot id: A0A9E6T4S4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

2745514:HU731 RS24660
gene id: 2745514:HU731_RS24660
uniprot id: A0A9E6ND81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS07385
gene id: 2745514:HU731_RS07385
uniprot id: A0A9E6NHE0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

2745514:HU731 RS18465
gene id: 2745514:HU731_RS18465
uniprot id: A0A9E6NAW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS17435
gene id: 2745514:HU731_RS17435
uniprot id: A0A9E6NA61
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2745514:HU731 RS09750
gene id: 2745514:HU731_RS09750
uniprot id: A0A9E6NHK2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS07665
gene id: 2745514:HU731_RS07665
uniprot id: A0A9E6T7E0
names: Similarity
messages: Belongs to the CvfB family.

2745514:HU731 RS10360
gene id: 2745514:HU731_RS10360
uniprot id: A0A9E6NHI7
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

2745514:HU731 RS12015
gene id: 2745514:HU731_RS12015
uniprot id: A0A9E6NI04
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS00660
gene id: 2745514:HU731_RS00660
uniprot id: A0A9E6NDZ8
names: Similarity
messages: Belongs to the transglycosylase Slt family.

2745514:HU731 RS17940
gene id: 2745514:HU731_RS17940
uniprot id: A0A9E6NA92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS20825
gene id: 2745514:HU731_RS20825
uniprot id: A0A9E6NBB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2745514:HU731 RS22410
gene id: 2745514:HU731_RS22410
uniprot id: A0A9E6T586
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS15265
gene id: 2745514:HU731_RS15265
uniprot id: A0A9E6N9E4
names: Similarity
messages: Belongs to the RutC family.

2745514:HU731 RS21400
gene id: 2745514:HU731_RS21400
uniprot id: A0A9E6T4W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

2745514:HU731 RS25370
gene id: 2745514:HU731_RS25370
uniprot id: A0A9E6NCY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

2745514:HU731 RS15290
gene id: 2745514:HU731_RS15290
uniprot id: A0A9E6T3Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

2745514:HU731 RS11275
gene id: 2745514:HU731_RS11275
uniprot id: A0A9E6NHT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

2745514:HU731 RS17720
gene id: 2745514:HU731_RS17720
uniprot id: A0A9E6NA91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

2745514:HU731 RS20410
gene id: 2745514:HU731_RS20410
uniprot id: A0A9E6NBM7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

2745514:HU731 RS16760
gene id: 2745514:HU731_RS16760
uniprot id: A0A9E6N9Z0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745514:HU731 RS26960
gene id: 2745514:HU731_RS26960
uniprot id: A0A9E6NDB0
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

2745514:HU731 RS12120
gene id: 2745514:HU731_RS12120
uniprot id: A0A9E6NJ05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

2745514:HU731 RS17705
gene id: 2745514:HU731_RS17705
uniprot id: A0A9E6NAE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

2745514:HU731 RS13265
gene id: 2745514:HU731_RS13265
uniprot id: A0A9E6NJE6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745514:HU731 RS12710
gene id: 2745514:HU731_RS12710
uniprot id: A0A9E6T8C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2745514:HU731 RS24945
gene id: 2745514:HU731_RS24945
uniprot id: A0A9E6ND09
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

2745514:HU731 RS24955
gene id: 2745514:HU731_RS24955
uniprot id: A0A9E6NCM8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

2745514:HU731 RS05155
gene id: 2745514:HU731_RS05155
uniprot id: A0A9E6NFY5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2745514:HU731 RS14590
gene id: 2745514:HU731_RS14590
uniprot id: A0A9E6N9L4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2745514:HU731 RS12230
gene id: 2745514:HU731_RS12230
uniprot id: A0A9E6NIH9
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS00355
gene id: 2745514:HU731_RS00355
uniprot id: A0A9E6NDV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS18705
gene id: 2745514:HU731_RS18705
uniprot id: A0A9E6NBA3
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

2745514:HU731 RS18260
gene id: 2745514:HU731_RS18260
uniprot id: A0A9E6NAV9
names: Similarity
messages: Belongs to the thioredoxin family.

2745514:HU731 RS15105
gene id: 2745514:HU731_RS15105
uniprot id: A0A9E6N9A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

2745514:HU731 RS10850
gene id: 2745514:HU731_RS10850
uniprot id: A0A9E6NHM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

2745514:HU731 RS25030
gene id: 2745514:HU731_RS25030
uniprot id: A0A9E6NCN8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

2745514:HU731 RS11280
gene id: 2745514:HU731_RS11280
uniprot id: A0A9E6NI66
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS24480
gene id: 2745514:HU731_RS24480
uniprot id: A0A9E6NCH1
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

2745514:HU731 RS24210
gene id: 2745514:HU731_RS24210
uniprot id: A0A9E6T5J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2745514:HU731 RS22425
gene id: 2745514:HU731_RS22425
uniprot id: A0A9E6NCL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2745514:HU731 RS05165
gene id: 2745514:HU731_RS05165
uniprot id: A0A9E6NG42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2745514:HU731 RS12800
gene id: 2745514:HU731_RS12800
uniprot id: A0A9E6T8G4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS04170
gene id: 2745514:HU731_RS04170
uniprot id: A0A9E6NFM9
names: Similarity
messages: Belongs to the UPF0434 family.

2745514:HU731 RS18040
gene id: 2745514:HU731_RS18040
uniprot id: A0A9E6T4F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

2745514:HU731 RS08695
gene id: 2745514:HU731_RS08695
uniprot id: A0A9E6NHW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

2745514:HU731 RS12185
gene id: 2745514:HU731_RS12185
uniprot id: A0A9E6NI26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

2745514:HU731 RS06980
gene id: 2745514:HU731_RS06980
uniprot id: A0A9E6NH88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

2745514:HU731 RS12650
gene id: 2745514:HU731_RS12650
uniprot id: A0A9E6T8F6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2745514:HU731 RS04645
gene id: 2745514:HU731_RS04645
uniprot id: A0A9E6NGG6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

2745514:HU731 RS17685
gene id: 2745514:HU731_RS17685
uniprot id: A0A9E6NA71
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

2745514:HU731 RS15230
gene id: 2745514:HU731_RS15230
uniprot id: A0A9E6T3T5
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

2745514:HU731 RS18350
gene id: 2745514:HU731_RS18350
uniprot id: A0A9E6T4G8
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

2745514:HU731 RS16075
gene id: 2745514:HU731_RS16075
uniprot id: A0A9E6T8Q4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

2745514:HU731 RS24700
gene id: 2745514:HU731_RS24700
uniprot id: A0A9E6NDL3
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

2745514:HU731 RS07140
gene id: 2745514:HU731_RS07140
uniprot id: A0A9E6NGM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

2745514:HU731 RS26585
gene id: 2745514:HU731_RS26585
uniprot id: A0A9E6T5Z4
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

2745514:HU731 RS10265
gene id: 2745514:HU731_RS10265
uniprot id: A0A9E6T7Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

2745514:HU731 RS23165
gene id: 2745514:HU731_RS23165
uniprot id: A0A9E6NC57
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745514:HU731 RS25035
gene id: 2745514:HU731_RS25035
uniprot id: A0A9E6NCV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

2745514:HU731 RS10295
gene id: 2745514:HU731_RS10295
uniprot id: A0A9E6NHP9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

2745514:HU731 RS16195
gene id: 2745514:HU731_RS16195
uniprot id: A0A9E6NAA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

2745514:HU731 RS09880
gene id: 2745514:HU731_RS09880
uniprot id: A0A9E6NI95
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

2745514:HU731 RS10520
gene id: 2745514:HU731_RS10520
uniprot id: A0A9E6NIH2
names: Similarity
messages: Belongs to the YfgM family.

2745514:HU731 RS12635
gene id: 2745514:HU731_RS12635
uniprot id: A0A9E6T8C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2745514:HU731 RS16250
gene id: 2745514:HU731_RS16250
uniprot id: A0A9E6T3Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

2745514:HU731 RS24375
gene id: 2745514:HU731_RS24375
uniprot id: A0A9E6T5D6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

2745514:HU731 RS09835
gene id: 2745514:HU731_RS09835
uniprot id: A0A9E6NHA5
names: Similarity
messages: Belongs to the SlyX family.

2745514:HU731 RS09845
gene id: 2745514:HU731_RS09845
uniprot id: A0A9E6T806
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

2745514:HU731 RS14160
gene id: 2745514:HU731_RS14160
uniprot id: A0A9E6N9H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745514:HU731 RS20140
gene id: 2745514:HU731_RS20140
uniprot id: A0A9E6NBT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745514:HU731 RS11770
gene id: 2745514:HU731_RS11770
uniprot id: A0A9E6T879
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745514:HU731 RS20840
gene id: 2745514:HU731_RS20840
uniprot id: A0A9E6T4Z2
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

2745514:HU731 RS03055
gene id: 2745514:HU731_RS03055
uniprot id: A0A9E6NFF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745514:HU731 RS12255
gene id: 2745514:HU731_RS12255
uniprot id: A0A9E6T8C5
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.

2745514:HU731 RS10280
gene id: 2745514:HU731_RS10280
uniprot id: A0A9E6NIE8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2745514:HU731 RS04290
gene id: 2745514:HU731_RS04290
uniprot id: A0A9E6T6X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

2745514:HU731 RS05860
gene id: 2745514:HU731_RS05860
uniprot id: A0A9E6T769
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

2745514:HU731 RS15060
gene id: 2745514:HU731_RS15060
uniprot id: A0A9E6T3U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS12675
gene id: 2745514:HU731_RS12675
uniprot id: A0A9E6NJ84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

2745514:HU731 RS18045
gene id: 2745514:HU731_RS18045
uniprot id: A0A9E6T4C9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

2745514:HU731 RS27260
gene id: 2745514:HU731_RS27260
uniprot id: A0A9E6T601
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS11050
gene id: 2745514:HU731_RS11050
uniprot id: A0A9E6T892
names: Similarity
messages: Belongs to the YjdM family.

2745514:HU731 RS18575
gene id: 2745514:HU731_RS18575
uniprot id: A0A9E6T4J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

2745514:HU731 RS15575
gene id: 2745514:HU731_RS15575
uniprot id: A0A9E6N9I9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

2745514:HU731 RS24440
gene id: 2745514:HU731_RS24440
uniprot id: A0A9E6T5L5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

2745514:HU731 RS15600
gene id: 2745514:HU731_RS15600
uniprot id: A0A9E6N9M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745514:HU731 RS20895
gene id: 2745514:HU731_RS20895
uniprot id: A0A9E6NB86
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

2745514:HU731 RS15070
gene id: 2745514:HU731_RS15070
uniprot id: A0A9E6T3S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

2745514:HU731 RS10050
gene id: 2745514:HU731_RS10050
uniprot id: A0A9E6NHC8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

2745514:HU731 RS20340
gene id: 2745514:HU731_RS20340
uniprot id: A0A9E6NB02
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

2745514:HU731 RS11545
gene id: 2745514:HU731_RS11545
uniprot id: A0A9E6T873
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

2745514:HU731 RS10605
gene id: 2745514:HU731_RS10605
uniprot id: A0A9E6NHJ8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

2745514:HU731 RS17795
gene id: 2745514:HU731_RS17795
uniprot id: A0A9E6NA99
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

2745514:HU731 RS16635
gene id: 2745514:HU731_RS16635
uniprot id: A0A9E6T446
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745514:HU731 RS14080
gene id: 2745514:HU731_RS14080
uniprot id: A0A9E6NIY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

2745514:HU731 RS22010
gene id: 2745514:HU731_RS22010
uniprot id: A0A9E6T523
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

2745514:HU731 RS22310
gene id: 2745514:HU731_RS22310
uniprot id: A0A9E6NCC1
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

2745514:HU731 RS16025
gene id: 2745514:HU731_RS16025
uniprot id: A0A9E6NA31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2745514:HU731 RS04915
gene id: 2745514:HU731_RS04915
uniprot id: A0A9E6NFK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2745514:HU731 RS06880
gene id: 2745514:HU731_RS06880
uniprot id: A0A9E6T7D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

2745514:HU731 RS01140
gene id: 2745514:HU731_RS01140
uniprot id: A0A9E6T6C2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745514:HU731 RS11285
gene id: 2745514:HU731_RS11285
uniprot id: A0A9E6T898
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

2745514:HU731 RS19710
gene id: 2745514:HU731_RS19710
uniprot id: A0A9E6T4J2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

2745514:HU731 RS27100
gene id: 2745514:HU731_RS27100
uniprot id: A0A9E6T633
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS15210
gene id: 2745514:HU731_RS15210
uniprot id: A0A9E6T3X4
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

2745514:HU731 RS16095
gene id: 2745514:HU731_RS16095
uniprot id: A0A9E6T413
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

2745514:HU731 RS19335
gene id: 2745514:HU731_RS19335
uniprot id: A0A9E6NAP5
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS11035
gene id: 2745514:HU731_RS11035
uniprot id: A0A9E6T882
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2745514:HU731 RS02595
gene id: 2745514:HU731_RS02595
uniprot id: A0A9E6T6M1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745514:HU731 RS13930
gene id: 2745514:HU731_RS13930
uniprot id: A0A9E6T8R8
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS10260
gene id: 2745514:HU731_RS10260
uniprot id: A0A9E6T844
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

2745514:HU731 RS07150
gene id: 2745514:HU731_RS07150
uniprot id: A0A9E6NGM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

2745514:HU731 RS17870
gene id: 2745514:HU731_RS17870
uniprot id: A0A9E6NAA6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2745514:HU731 RS07870
gene id: 2745514:HU731_RS07870
uniprot id: A0A9E6NGL3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

2745514:HU731 RS16400
gene id: 2745514:HU731_RS16400
uniprot id: A0A9E6T400
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

2745514:HU731 RS04620
gene id: 2745514:HU731_RS04620
uniprot id: A0A9E6T6Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS13130
gene id: 2745514:HU731_RS13130
uniprot id: A0A9E6NIF0
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

2745514:HU731 RS12435
gene id: 2745514:HU731_RS12435
uniprot id: A0A9E6NIV5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

2745514:HU731 RS08235
gene id: 2745514:HU731_RS08235
uniprot id: A0A9E6NHQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

2745514:HU731 RS04260
gene id: 2745514:HU731_RS04260
uniprot id: A0A9E6NFE9
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS11185
gene id: 2745514:HU731_RS11185
uniprot id: A0A9E6T893
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Cyclase 1 superfamily. KynB family.
messages: Binds 2 zinc ions per subunit.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
messages: Homodimer.

2745514:HU731 RS21720
gene id: 2745514:HU731_RS21720
uniprot id: A0A9E6NBF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS23520
gene id: 2745514:HU731_RS23520
uniprot id: A0A9E6ND67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Sulfur carrier protein which probably makes part of a sulfur-relay system.

2745514:HU731 RS11745
gene id: 2745514:HU731_RS11745
uniprot id: A0A9E6NHY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

2745514:HU731 RS12615
gene id: 2745514:HU731_RS12615
uniprot id: A0A9E6NIN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

2745514:HU731 RS20480
gene id: 2745514:HU731_RS20480
uniprot id: A0A9E6NBV4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

2745514:HU731 RS26580
gene id: 2745514:HU731_RS26580
uniprot id: A0A9E6NDW4
names: Similarity
messages: Belongs to the DapA family.

2745514:HU731 RS19735
gene id: 2745514:HU731_RS19735
uniprot id: A0A9E6NBM2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

2745514:HU731 RS08890
gene id: 2745514:HU731_RS08890
uniprot id: A0A9E6NHY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

2745514:HU731 RS13035
gene id: 2745514:HU731_RS13035
uniprot id: A0A9E6NIE6
names: Similarity
messages: Belongs to the UPF0229 family.

2745514:HU731 RS20580
gene id: 2745514:HU731_RS20580
uniprot id: A0A9E6NB88
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

2745514:HU731 RS19760
gene id: 2745514:HU731_RS19760
uniprot id: A0A9E6NAY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PagL family.
messages: Cell outer membrane
messages: Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety.
messages: Homodimer.

2745514:HU731 RS23330
gene id: 2745514:HU731_RS23330
uniprot id: A0A9E6NCM6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745514:HU731 RS07955
gene id: 2745514:HU731_RS07955
uniprot id: A0A9E6T7P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

2745514:HU731 RS14795
gene id: 2745514:HU731_RS14795
uniprot id: A0A9E6N930
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

2745514:HU731 RS23170
gene id: 2745514:HU731_RS23170
uniprot id: A0A9E6NC71
names: Similarity
messages: Belongs to the RseA family.

2745514:HU731 RS09785
gene id: 2745514:HU731_RS09785
uniprot id: A0A9E6T815
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

2745514:HU731 RS12700
gene id: 2745514:HU731_RS12700
uniprot id: A0A9E6NIM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2745514:HU731 RS15490
gene id: 2745514:HU731_RS15490
uniprot id: A0A9E6N9H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

2745514:HU731 RS15260
gene id: 2745514:HU731_RS15260
uniprot id: A0A9E6N9Q0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

2745514:HU731 RS16180
gene id: 2745514:HU731_RS16180
uniprot id: A0A9E6T418
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

2745514:HU731 RS21640
gene id: 2745514:HU731_RS21640
uniprot id: A0A9E6T505
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

2745514:HU731 RS04635
gene id: 2745514:HU731_RS04635
uniprot id: A0A9E6NGF2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

2745514:HU731 RS07225
gene id: 2745514:HU731_RS07225
uniprot id: A0A9E6NGN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2745514:HU731 RS12300
gene id: 2745514:HU731_RS12300
uniprot id: A0A9E6NI53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS21600
gene id: 2745514:HU731_RS21600
uniprot id: A0A9E6NBH7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

2745514:HU731 RS17655
gene id: 2745514:HU731_RS17655
uniprot id: A0A9E6T4B2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745514:HU731 RS16435
gene id: 2745514:HU731_RS16435
uniprot id: A0A9E6NA42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS13950
gene id: 2745514:HU731_RS13950
uniprot id: A0A9E6T8N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

2745514:HU731 RS04605
gene id: 2745514:HU731_RS04605
uniprot id: A0A9E6T6Z4
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS17065
gene id: 2745514:HU731_RS17065
uniprot id: A0A9E6NAG2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2745514:HU731 RS18635
gene id: 2745514:HU731_RS18635
uniprot id: A0A9E6NAS9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

2745514:HU731 RS19600
gene id: 2745514:HU731_RS19600
uniprot id: A0A9E6NAW9
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.

2745514:HU731 RS10350
gene id: 2745514:HU731_RS10350
uniprot id: A0A9E6NID1
names: Similarity
messages: Belongs to the YkuD family.

2745514:HU731 RS09850
gene id: 2745514:HU731_RS09850
uniprot id: A0A9E6T7V9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

2745514:HU731 RS10835
gene id: 2745514:HU731_RS10835
uniprot id: A0A9E6NHP7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

2745514:HU731 RS26735
gene id: 2745514:HU731_RS26735
uniprot id: A0A9E6ND97
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS19075
gene id: 2745514:HU731_RS19075
uniprot id: A0A9E6NAM8
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

2745514:HU731 RS04425
gene id: 2745514:HU731_RS04425
uniprot id: A0A9E6NFG2
names: Cofactor
messages: Can also use Mn(2+) ion.

2745514:HU731 RS10625
gene id: 2745514:HU731_RS10625
uniprot id: A0A9E6T856
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS20400
gene id: 2745514:HU731_RS20400
uniprot id: A0A9E6NBU5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

2745514:HU731 RS02070
gene id: 2745514:HU731_RS02070
uniprot id: A0A9E6NEH7
names: Similarity
messages: Belongs to the UDPGP type 2 family.

2745514:HU731 RS20135
gene id: 2745514:HU731_RS20135
uniprot id: A0A9E6NAX9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2745514:HU731 RS12450
gene id: 2745514:HU731_RS12450
uniprot id: A0A9E6NJ53
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

2745514:HU731 RS02580
gene id: 2745514:HU731_RS02580
uniprot id: A0A9E6NEX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

2745514:HU731 RS19095
gene id: 2745514:HU731_RS19095
uniprot id: A0A9E6NB42
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

2745514:HU731 RS13080
gene id: 2745514:HU731_RS13080
uniprot id: A0A9E6NIE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

2745514:HU731 RS02810
gene id: 2745514:HU731_RS02810
uniprot id: A0A9E6NF04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP.
messages: Membrane

2745514:HU731 RS19855
gene id: 2745514:HU731_RS19855
uniprot id: A0A9E6T4Q0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

2745514:HU731 RS12580
gene id: 2745514:HU731_RS12580
uniprot id: A0A9E6NI81
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

2745514:HU731 RS06055
gene id: 2745514:HU731_RS06055
uniprot id: A0A9E6T7D1
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS09330
gene id: 2745514:HU731_RS09330
uniprot id: A0A9E6NHD2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

2745514:HU731 RS08005
gene id: 2745514:HU731_RS08005
uniprot id: A0A9E6NHM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

2745514:HU731 RS05840
gene id: 2745514:HU731_RS05840
uniprot id: A0A9E6NFW2
names: Similarity
messages: Belongs to the asparaginase 1 family.

2745514:HU731 RS13730
gene id: 2745514:HU731_RS13730
uniprot id: A0A9E6NIL1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

2745514:HU731 RS11720
gene id: 2745514:HU731_RS11720
uniprot id: A0A9E6NIQ6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

2745514:HU731 RS25365
gene id: 2745514:HU731_RS25365
uniprot id: A0A9E6ND55
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS07360
gene id: 2745514:HU731_RS07360
uniprot id: A0A9E6T7G2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

2745514:HU731 RS16280
gene id: 2745514:HU731_RS16280
uniprot id: A0A9E6N9U0
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

2745514:HU731 RS01180
gene id: 2745514:HU731_RS01180
uniprot id: A0A9E6NE48
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS22480
gene id: 2745514:HU731_RS22480
uniprot id: A0A9E6T546
names: Subcellular Location Annotation
messages: Cytoplasm

2745514:HU731 RS13350
gene id: 2745514:HU731_RS13350
uniprot id: A0A9E6NIZ2
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

2745514:HU731 RS11140
gene id: 2745514:HU731_RS11140
uniprot id: A0A9E6NIL4
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

2745514:HU731 RS27745
gene id: 2745514:HU731_RS27745
uniprot id: A0A9E6NEL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

2745514:HU731 RS12640
gene id: 2745514:HU731_RS12640
uniprot id: A0A9E6T8A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2745514:HU731 RS12690
gene id: 2745514:HU731_RS12690
uniprot id: A0A9E6NIU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2745514:HU731 RS20425
gene id: 2745514:HU731_RS20425
uniprot id: A0A9E6NB28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

2745514:HU731 RS04065
gene id: 2745514:HU731_RS04065
uniprot id: A0A9E6NFK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ivy family.
messages: Periplasm

2745514:HU731 RS22320
gene id: 2745514:HU731_RS22320
uniprot id: A0A9E6T538
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

2745514:HU731 RS24595
gene id: 2745514:HU731_RS24595
uniprot id: A0A9E6T5G5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS10055
gene id: 2745514:HU731_RS10055
uniprot id: A0A9E6NHP4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745514:HU731 RS19880
gene id: 2745514:HU731_RS19880
uniprot id: A0A9E6NAV0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

2745514:HU731 RS19360
gene id: 2745514:HU731_RS19360
uniprot id: A0A9E6T4M3
names: Similarity
messages: Belongs to the IMPACT family.

2745514:HU731 RS24180
gene id: 2745514:HU731_RS24180
uniprot id: A0A9E6NDA1
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

2745514:HU731 RS00395
gene id: 2745514:HU731_RS00395
uniprot id: A0A9E6NE10
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2745514:HU731 RS12705
gene id: 2745514:HU731_RS12705
uniprot id: A0A9E6T8J5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2745514:HU731 RS08910
gene id: 2745514:HU731_RS08910
uniprot id: A0A9E6NH00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

2745514:HU731 RS21060
gene id: 2745514:HU731_RS21060
uniprot id: A0A9E6NBF8
names: Similarity
messages: Belongs to the PhoH family.

2745514:HU731 RS14785
gene id: 2745514:HU731_RS14785
uniprot id: A0A9E6N9K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

2745514:HU731 RS17095
gene id: 2745514:HU731_RS17095
uniprot id: A0A9E6NA18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

2745514:HU731 RS22325
gene id: 2745514:HU731_RS22325
uniprot id: A0A9E6T521
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

2745514:HU731 RS25230
gene id: 2745514:HU731_RS25230
uniprot id: A0A9E6NCV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

2745514:HU731 RS10545
gene id: 2745514:HU731_RS10545
uniprot id: A0A9E6NHX5
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

2745514:HU731 RS21120
gene id: 2745514:HU731_RS21120
uniprot id: A0A9E6NBV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS09000
gene id: 2745514:HU731_RS09000
uniprot id: A0A9E6NHY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

2745514:HU731 RS17805
gene id: 2745514:HU731_RS17805
uniprot id: A0A9E6NAQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

2745514:HU731 RS18545
gene id: 2745514:HU731_RS18545
uniprot id: A0A9E6NAX4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

2745514:HU731 RS10150
gene id: 2745514:HU731_RS10150
uniprot id: A0A9E6NHT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2745514:HU731 RS07255
gene id: 2745514:HU731_RS07255
uniprot id: A0A9E6T7E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS27390
gene id: 2745514:HU731_RS27390
uniprot id: A0A9E6NDL5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

2745514:HU731 RS08930
gene id: 2745514:HU731_RS08930
uniprot id: A0A9E6NHA6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS13175
gene id: 2745514:HU731_RS13175
uniprot id: A0A9E6NJJ3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745514:HU731 RS04370
gene id: 2745514:HU731_RS04370
uniprot id: A0A9E6T6U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

2745514:HU731 RS02695
gene id: 2745514:HU731_RS02695
uniprot id: A0A9E6NFP6
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS11715
gene id: 2745514:HU731_RS11715
uniprot id: A0A9E6NHV6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745514:HU731 RS11530
gene id: 2745514:HU731_RS11530
uniprot id: A0A9E6T864
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

2745514:HU731 RS12160
gene id: 2745514:HU731_RS12160
uniprot id: A0A9E6T899
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

2745514:HU731 RS12655
gene id: 2745514:HU731_RS12655
uniprot id: A0A9E6NI91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

2745514:HU731 RS14450
gene id: 2745514:HU731_RS14450
uniprot id: A0A9E6T8W7
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

2745514:HU731 RS16580
gene id: 2745514:HU731_RS16580
uniprot id: A0A9E6NAC7
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS16530
gene id: 2745514:HU731_RS16530
uniprot id: A0A9E6N9V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.
messages: Catalyzes the proton-dependent transport of glutamate and aspartate.
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS18825
gene id: 2745514:HU731_RS18825
uniprot id: A0A9E6T4J3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

2745514:HU731 RS17770
gene id: 2745514:HU731_RS17770
uniprot id: A0A9E6NAZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

2745514:HU731 RS24735
gene id: 2745514:HU731_RS24735
uniprot id: A0A9E6ND92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

2745514:HU731 RS11755
gene id: 2745514:HU731_RS11755
uniprot id: A0A9E6NHZ3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

2745514:HU731 RS04020
gene id: 2745514:HU731_RS04020
uniprot id: A0A9E6T710
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745514:HU731 RS17230
gene id: 2745514:HU731_RS17230
uniprot id: A0A9E6T486
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

2745514:HU731 RS06725
gene id: 2745514:HU731_RS06725
uniprot id: A0A9E6T7C6
names: Subcellular Location Annotation
messages: Membrane

2745514:HU731 RS24115
gene id: 2745514:HU731_RS24115
uniprot id: A0A9E6NCN9
names: Similarity
messages: Belongs to the peptidase S33 family.

2745514:HU731 RS15995
gene id: 2745514:HU731_RS15995
uniprot id: A0A9E6T412
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

2745514:HU731 RS19225
gene id: 2745514:HU731_RS19225
uniprot id: A0A9E6T4L2
names: Similarity
messages: Belongs to the GSP E family.

2745514:HU731 RS04400
gene id: 2745514:HU731_RS04400
uniprot id: A0A9E6NFC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

2745514:HU731 RS12780
gene id: 2745514:HU731_RS12780
uniprot id: A0A9E6T8J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2745514:HU731 RS10580
gene id: 2745514:HU731_RS10580
uniprot id: A0A9E6NIG2
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

2745514:HU731 RS08600
gene id: 2745514:HU731_RS08600
uniprot id: A0A9E6T7U2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

2745514:HU731 RS08400
gene id: 2745514:HU731_RS08400
uniprot id: A0A9E6NHS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

2745514:HU731 RS17935
gene id: 2745514:HU731_RS17935
uniprot id: A0A9E6NAM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS07035
gene id: 2745514:HU731_RS07035
uniprot id: A0A9E6NG57
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745514:HU731 RS11510
gene id: 2745514:HU731_RS11510
uniprot id: A0A9E6NJ34
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

2745514:HU731 RS07635
gene id: 2745514:HU731_RS07635
uniprot id: A0A9E6NGH9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745514:HU731 RS20965
gene id: 2745514:HU731_RS20965
uniprot id: A0A9E6NBN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell inner membrane
messages: Membrane

2745514:HU731 RS23180
gene id: 2745514:HU731_RS23180
uniprot id: A0A9E6T5D4
names: Function
messages: Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions.

2745514:HU731 RS17815
gene id: 2745514:HU731_RS17815
uniprot id: A0A9E6T4D4
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

2745514:HU731 RS27680
gene id: 2745514:HU731_RS27680
uniprot id: A0A9E6NEJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm

2745514:HU731 RS22595
gene id: 2745514:HU731_RS22595
uniprot id: A0A9E6NCP6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS09470
gene id: 2745514:HU731_RS09470
uniprot id: A0A9E6NI25
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

2745514:HU731 RS27090
gene id: 2745514:HU731_RS27090
uniprot id: A0A9E6T5Z0
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

2745514:HU731 RS07570
gene id: 2745514:HU731_RS07570
uniprot id: A0A9E6NGH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

2745514:HU731 RS22700
gene id: 2745514:HU731_RS22700
uniprot id: A0A9E6T5A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

2745514:HU731 RS08915
gene id: 2745514:HU731_RS08915
uniprot id: A0A9E6NHX8
names: Similarity
messages: Belongs to the aspartokinase family.

2745514:HU731 RS06910
gene id: 2745514:HU731_RS06910
uniprot id: A0A9E6NGK0
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

2745514:HU731 RS19865
gene id: 2745514:HU731_RS19865
uniprot id: A0A9E6T4K3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

2745514:HU731 RS22340
gene id: 2745514:HU731_RS22340
uniprot id: A0A9E6NBP4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS22485
gene id: 2745514:HU731_RS22485
uniprot id: A0A9E6T541
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745514:HU731 RS04660
gene id: 2745514:HU731_RS04660
uniprot id: A0A9E6NFS8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2745514:HU731 RS14625
gene id: 2745514:HU731_RS14625
uniprot id: A0A9E6N973
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745514:HU731 RS21730
gene id: 2745514:HU731_RS21730
uniprot id: A0A9E6NCA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS12150
gene id: 2745514:HU731_RS12150
uniprot id: A0A9E6NIH1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

2745514:HU731 RS12745
gene id: 2745514:HU731_RS12745
uniprot id: A0A9E6NIG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2745514:HU731 RS07275
gene id: 2745514:HU731_RS07275
uniprot id: A0A9E6NG94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

2745514:HU731 RS27075
gene id: 2745514:HU731_RS27075
uniprot id: A0A9E6NDD7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745514:HU731 RS24925
gene id: 2745514:HU731_RS24925
uniprot id: A0A9E6NDJ4
names: Similarity
messages: Belongs to the citrate synthase family.

2745514:HU731 RS22335
gene id: 2745514:HU731_RS22335
uniprot id: A0A9E6T543
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

2745514:HU731 RS03105
gene id: 2745514:HU731_RS03105
uniprot id: A0A9E6NFX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2745514:HU731 RS13430
gene id: 2745514:HU731_RS13430
uniprot id: A0A9E6NJG4
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.