2745510:HU754 RS21255
gene id: 2745510:HU754_RS21255
uniprot id: A0A9E6TA72
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745510:HU754 RS28350
gene id: 2745510:HU754_RS28350
uniprot id: A0A9E6NP23
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

2745510:HU754 RS25185
gene id: 2745510:HU754_RS25185
uniprot id: A0A9E6NNQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

2745510:HU754 RS00975
gene id: 2745510:HU754_RS00975
uniprot id: A0A9E6TBR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

2745510:HU754 RS24890
gene id: 2745510:HU754_RS24890
uniprot id: A0A9E6NMS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

2745510:HU754 RS05590
gene id: 2745510:HU754_RS05590
uniprot id: A0A9E6NRD0
names: Similarity
messages: Belongs to the DapA family.

2745510:HU754 RS00135
gene id: 2745510:HU754_RS00135
uniprot id: A0A9E6NUF1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745510:HU754 RS13530
gene id: 2745510:HU754_RS13530
uniprot id: A0A9E6TE50
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

2745510:HU754 RS05255
gene id: 2745510:HU754_RS05255
uniprot id: A0A9E6NRZ2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

2745510:HU754 RS21955
gene id: 2745510:HU754_RS21955
uniprot id: A0A9E6NLS6
names: Similarity
messages: Belongs to the fabD family.

2745510:HU754 RS06960
gene id: 2745510:HU754_RS06960
uniprot id: A0A9E6TCI4
names: Subcellular Location Annotation
messages: Cytoplasm

2745510:HU754 RS22375
gene id: 2745510:HU754_RS22375
uniprot id: A0A9E6NM24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

2745510:HU754 RS24610
gene id: 2745510:HU754_RS24610
uniprot id: A0A9E6NMN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

2745510:HU754 RS28810
gene id: 2745510:HU754_RS28810
uniprot id: A0A9E6TBH0
names: Similarity
messages: Belongs to the glutamine synthetase family.

2745510:HU754 RS08205
gene id: 2745510:HU754_RS08205
uniprot id: A0A9E6NSU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745510:HU754 RS26880
gene id: 2745510:HU754_RS26880
uniprot id: A0A9E6NPR5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

2745510:HU754 RS00120
gene id: 2745510:HU754_RS00120
uniprot id: A0A9E6NQQ3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2745510:HU754 RS10075
gene id: 2745510:HU754_RS10075
uniprot id: A0A9E6NTY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ureidoglycolate lyase family.
messages: Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.
messages: Homodimer.

2745510:HU754 RS09280
gene id: 2745510:HU754_RS09280
uniprot id: A0A9E6NTX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2745510:HU754 RS25810
gene id: 2745510:HU754_RS25810
uniprot id: A0A9E6TAX4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2745510:HU754 RS00460
gene id: 2745510:HU754_RS00460
uniprot id: A0A9E6NPI2
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

2745510:HU754 RS22260
gene id: 2745510:HU754_RS22260
uniprot id: A0A9E6NLU1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

2745510:HU754 RS01540
gene id: 2745510:HU754_RS01540
uniprot id: A0A9E6NQP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

2745510:HU754 RS19300
gene id: 2745510:HU754_RS19300
uniprot id: A0A9E6T9S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2745510:HU754 RS24725
gene id: 2745510:HU754_RS24725
uniprot id: A0A9E6TAR1
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

2745510:HU754 RS22445
gene id: 2745510:HU754_RS22445
uniprot id: A0A9E6NMS3
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

2745510:HU754 RS01440
gene id: 2745510:HU754_RS01440
uniprot id: A0A9E6TBM9
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

2745510:HU754 RS03765
gene id: 2745510:HU754_RS03765
uniprot id: A0A9E6TC84
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

2745510:HU754 RS20535
gene id: 2745510:HU754_RS20535
uniprot id: A0A9E6T9T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

2745510:HU754 RS01835
gene id: 2745510:HU754_RS01835
uniprot id: A0A9E6NQ09
names: Similarity
messages: Belongs to the band 7/mec-2 family.

2745510:HU754 RS10020
gene id: 2745510:HU754_RS10020
uniprot id: A0A9E6NT54
names: Similarity
messages: Belongs to the peptidase M18 family.

2745510:HU754 RS23920
gene id: 2745510:HU754_RS23920
uniprot id: A0A9E6NMF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745510:HU754 RS06830
gene id: 2745510:HU754_RS06830
uniprot id: A0A9E6NRT8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

2745510:HU754 RS19645
gene id: 2745510:HU754_RS19645
uniprot id: A0A9E6T9X3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

2745510:HU754 RS09595
gene id: 2745510:HU754_RS09595
uniprot id: A0A9E6NTS8
names: Similarity
messages: Belongs to the citrate synthase family.

2745510:HU754 RS07190
gene id: 2745510:HU754_RS07190
uniprot id: A0A9E6TCV4
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2745510:HU754 RS23030
gene id: 2745510:HU754_RS23030
uniprot id: A0A9E6NNB5
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

2745510:HU754 RS29090
gene id: 2745510:HU754_RS29090
uniprot id: A0A9E6NPX2
names: Similarity
messages: Belongs to the UPF0178 family.

2745510:HU754 RS21520
gene id: 2745510:HU754_RS21520
uniprot id: A0A9E6TA53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2745510:HU754 RS04865
gene id: 2745510:HU754_RS04865
uniprot id: A0A9E6NRL3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745510:HU754 RS09390
gene id: 2745510:HU754_RS09390
uniprot id: A0A9E6NSW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

2745510:HU754 RS22635
gene id: 2745510:HU754_RS22635
uniprot id: A0A9E6NLY6
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

2745510:HU754 RS29235
gene id: 2745510:HU754_RS29235
uniprot id: A0A9E6NPH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

2745510:HU754 RS05295
gene id: 2745510:HU754_RS05295
uniprot id: A0A9E6NRS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

2745510:HU754 RS24360
gene id: 2745510:HU754_RS24360
uniprot id: A0A9E6NNU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

2745510:HU754 RS23165
gene id: 2745510:HU754_RS23165
uniprot id: A0A9E6TA86
names: Similarity
messages: Belongs to the carbamate kinase family.

2745510:HU754 RS23750
gene id: 2745510:HU754_RS23750
uniprot id: A0A9E6NN87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2745510:HU754 RS00220
gene id: 2745510:HU754_RS00220
uniprot id: A0A9E6NQ38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

2745510:HU754 RS03025
gene id: 2745510:HU754_RS03025
uniprot id: A0A9E6NR90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

2745510:HU754 RS07135
gene id: 2745510:HU754_RS07135
uniprot id: A0A9E6NSP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2745510:HU754 RS11555
gene id: 2745510:HU754_RS11555
uniprot id: A0A9E6TDT0
names: Similarity
messages: Belongs to the ClpA/ClpB family.

2745510:HU754 RS27825
gene id: 2745510:HU754_RS27825
uniprot id: A0A9E6NNV8
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

2745510:HU754 RS23925
gene id: 2745510:HU754_RS23925
uniprot id: A0A9E6NMT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745510:HU754 RS21750
gene id: 2745510:HU754_RS21750
uniprot id: A0A9E6TA78
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

2745510:HU754 RS09025
gene id: 2745510:HU754_RS09025
uniprot id: A0A9E6TDB8
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

2745510:HU754 RS07025
gene id: 2745510:HU754_RS07025
uniprot id: A0A9E6TCU8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2745510:HU754 RS11010
gene id: 2745510:HU754_RS11010
uniprot id: A0A9E6TDQ6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

2745510:HU754 RS22365
gene id: 2745510:HU754_RS22365
uniprot id: A0A9E6NLV8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

2745510:HU754 RS25815
gene id: 2745510:HU754_RS25815
uniprot id: A0A9E6TAS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2745510:HU754 RS08320
gene id: 2745510:HU754_RS08320
uniprot id: A0A9E6NTL4
names: Similarity
messages: Belongs to the RseA family.

2745510:HU754 RS21680
gene id: 2745510:HU754_RS21680
uniprot id: A0A9E6NLM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

2745510:HU754 RS06475
gene id: 2745510:HU754_RS06475
uniprot id: A0A9E6TCG4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745510:HU754 RS28120
gene id: 2745510:HU754_RS28120
uniprot id: A0A9E6TBF4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2745510:HU754 RS28455
gene id: 2745510:HU754_RS28455
uniprot id: A0A9E6NP75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

2745510:HU754 RS07420
gene id: 2745510:HU754_RS07420
uniprot id: A0A9E6TCW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

2745510:HU754 RS26825
gene id: 2745510:HU754_RS26825
uniprot id: A0A9E6NP41
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

2745510:HU754 RS09275
gene id: 2745510:HU754_RS09275
uniprot id: A0A9E6NTH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

2745510:HU754 RS05315
gene id: 2745510:HU754_RS05315
uniprot id: A0A9E6TCL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

2745510:HU754 RS02035
gene id: 2745510:HU754_RS02035
uniprot id: A0A9E6TC32
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

2745510:HU754 RS14030
gene id: 2745510:HU754_RS14030
uniprot id: A0A9E6TDX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

2745510:HU754 RS27360
gene id: 2745510:HU754_RS27360
uniprot id: A0A9E6TBB4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

2745510:HU754 RS07160
gene id: 2745510:HU754_RS07160
uniprot id: A0A9E6NSE7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

2745510:HU754 RS21685
gene id: 2745510:HU754_RS21685
uniprot id: A0A9E6NMG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

2745510:HU754 RS13355
gene id: 2745510:HU754_RS13355
uniprot id: A0A9E6TE40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

2745510:HU754 RS25225
gene id: 2745510:HU754_RS25225
uniprot id: A0A9E6TAN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745510:HU754 RS05745
gene id: 2745510:HU754_RS05745
uniprot id: A0A9E6NRE7
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

2745510:HU754 RS28690
gene id: 2745510:HU754_RS28690
uniprot id: A0A9E6NPA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

2745510:HU754 RS05800
gene id: 2745510:HU754_RS05800
uniprot id: A0A9E6TCW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745510:HU754 RS28010
gene id: 2745510:HU754_RS28010
uniprot id: A0A9E6NPS1
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

2745510:HU754 RS28345
gene id: 2745510:HU754_RS28345
uniprot id: A0A9E6TBG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

2745510:HU754 RS03830
gene id: 2745510:HU754_RS03830
uniprot id: A0A9E6NR53
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

2745510:HU754 RS01875
gene id: 2745510:HU754_RS01875
uniprot id: A0A9E6NQU2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2745510:HU754 RS23235
gene id: 2745510:HU754_RS23235
uniprot id: A0A9E6TAI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2745510:HU754 RS13115
gene id: 2745510:HU754_RS13115
uniprot id: A0A9E6TDR6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

2745510:HU754 RS05680
gene id: 2745510:HU754_RS05680
uniprot id: A0A9E6NRJ0
names: Similarity
messages: Belongs to the peptidase U62 family.

2745510:HU754 RS28125
gene id: 2745510:HU754_RS28125
uniprot id: A0A9E6NNZ0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

2745510:HU754 RS22065
gene id: 2745510:HU754_RS22065
uniprot id: A0A9E6TA96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

2745510:HU754 RS27030
gene id: 2745510:HU754_RS27030
uniprot id: A0A9E6NPT6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2745510:HU754 RS03685
gene id: 2745510:HU754_RS03685
uniprot id: A0A9E6TCE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

2745510:HU754 RS26810
gene id: 2745510:HU754_RS26810
uniprot id: A0A9E6NNF3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

2745510:HU754 RS26525
gene id: 2745510:HU754_RS26525
uniprot id: A0A9E6NND0
names: Similarity
messages: Belongs to the UPF0250 family.

2745510:HU754 RS20550
gene id: 2745510:HU754_RS20550
uniprot id: A0A9E6NL80
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

2745510:HU754 RS27090
gene id: 2745510:HU754_RS27090
uniprot id: A0A9E6TBA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2745510:HU754 RS27040
gene id: 2745510:HU754_RS27040
uniprot id: A0A9E6NPD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

2745510:HU754 RS06290
gene id: 2745510:HU754_RS06290
uniprot id: A0A9E6NSL6
names: Similarity
messages: Belongs to the PhoH family.

2745510:HU754 RS00715
gene id: 2745510:HU754_RS00715
uniprot id: A0A9E6NQI7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

2745510:HU754 RS25195
gene id: 2745510:HU754_RS25195
uniprot id: A0A9E6NNK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

2745510:HU754 RS04455
gene id: 2745510:HU754_RS04455
uniprot id: A0A9E6NRP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

2745510:HU754 RS08420
gene id: 2745510:HU754_RS08420
uniprot id: A0A9E6NST9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745510:HU754 RS03975
gene id: 2745510:HU754_RS03975
uniprot id: A0A9E6NRK1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745510:HU754 RS08480
gene id: 2745510:HU754_RS08480
uniprot id: A0A9E6NSD5
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

2745510:HU754 RS04185
gene id: 2745510:HU754_RS04185
uniprot id: A0A9E6NQU7
names: Similarity
messages: Belongs to the leucine-binding protein family.

2745510:HU754 RS25530
gene id: 2745510:HU754_RS25530
uniprot id: A0A9E6NNP4
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

2745510:HU754 RS03090
gene id: 2745510:HU754_RS03090
uniprot id: A0A9E6NRN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

2745510:HU754 RS01260
gene id: 2745510:HU754_RS01260
uniprot id: A0A9E6NQQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

2745510:HU754 RS20045
gene id: 2745510:HU754_RS20045
uniprot id: A0A9E6NLR7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

2745510:HU754 RS19315
gene id: 2745510:HU754_RS19315
uniprot id: A0A9E6NLL9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2745510:HU754 RS11600
gene id: 2745510:HU754_RS11600
uniprot id: A0A9E6NUB0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745510:HU754 RS05215
gene id: 2745510:HU754_RS05215
uniprot id: A0A9E6NR89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2745510:HU754 RS11305
gene id: 2745510:HU754_RS11305
uniprot id: A0A9E6NTJ2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2745510:HU754 RS05120
gene id: 2745510:HU754_RS05120
uniprot id: A0A9E6NRN8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745510:HU754 RS04795
gene id: 2745510:HU754_RS04795
uniprot id: A0A9E6NRL9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

2745510:HU754 RS15395
gene id: 2745510:HU754_RS15395
uniprot id: A0A9E6NJI5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

2745510:HU754 RS21745
gene id: 2745510:HU754_RS21745
uniprot id: A0A9E6TA03
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

2745510:HU754 RS07460
gene id: 2745510:HU754_RS07460
uniprot id: A0A9E6NS12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

2745510:HU754 RS23025
gene id: 2745510:HU754_RS23025
uniprot id: A0A9E6NMW0
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

2745510:HU754 RS19425
gene id: 2745510:HU754_RS19425
uniprot id: A0A9E6NLJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

2745510:HU754 RS04535
gene id: 2745510:HU754_RS04535
uniprot id: A0A9E6NS48
names: Similarity
messages: Belongs to the SUI1 family.

2745510:HU754 RS11550
gene id: 2745510:HU754_RS11550
uniprot id: A0A9E6TD79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

2745510:HU754 RS04190
gene id: 2745510:HU754_RS04190
uniprot id: A0A9E6NR93
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745510:HU754 RS02620
gene id: 2745510:HU754_RS02620
uniprot id: A0A9E6NQB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2745510:HU754 RS02170
gene id: 2745510:HU754_RS02170
uniprot id: A0A9E6TC20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745510:HU754 RS02735
gene id: 2745510:HU754_RS02735
uniprot id: A0A9E6NQB6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

2745510:HU754 RS27080
gene id: 2745510:HU754_RS27080
uniprot id: A0A9E6TAY2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2745510:HU754 RS05225
gene id: 2745510:HU754_RS05225
uniprot id: A0A9E6TCI6
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

2745510:HU754 RS11460
gene id: 2745510:HU754_RS11460
uniprot id: A0A9E6NTY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

2745510:HU754 RS24400
gene id: 2745510:HU754_RS24400
uniprot id: A0A9E6TAP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

2745510:HU754 RS21165
gene id: 2745510:HU754_RS21165
uniprot id: A0A9E6NLH9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

2745510:HU754 RS24840
gene id: 2745510:HU754_RS24840
uniprot id: A0A9E6TAW0
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

2745510:HU754 RS21675
gene id: 2745510:HU754_RS21675
uniprot id: A0A9E6TA64
names: Similarity
messages: Belongs to the UPF0270 family.

2745510:HU754 RS03775
gene id: 2745510:HU754_RS03775
uniprot id: A0A9E6NQP9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

2745510:HU754 RS28525
gene id: 2745510:HU754_RS28525
uniprot id: A0A9E6NPW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

2745510:HU754 RS18625
gene id: 2745510:HU754_RS18625
uniprot id: A0A9E6NKR8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

2745510:HU754 RS01990
gene id: 2745510:HU754_RS01990
uniprot id: A0A9E6NQ78
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2745510:HU754 RS26980
gene id: 2745510:HU754_RS26980
uniprot id: A0A9E6NPD3
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

2745510:HU754 RS00195
gene id: 2745510:HU754_RS00195
uniprot id: A0A9E6NQ83
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

2745510:HU754 RS26035
gene id: 2745510:HU754_RS26035
uniprot id: A0A9E6TAY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

2745510:HU754 RS08645
gene id: 2745510:HU754_RS08645
uniprot id: A0A9E6NTH1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745510:HU754 RS09755
gene id: 2745510:HU754_RS09755
uniprot id: A0A9E6NT75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

2745510:HU754 RS25865
gene id: 2745510:HU754_RS25865
uniprot id: A0A9E6NNT4
names: Similarity
messages: Belongs to the peptidase S16 family.

2745510:HU754 RS09605
gene id: 2745510:HU754_RS09605
uniprot id: A0A9E6NT59
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

2745510:HU754 RS28015
gene id: 2745510:HU754_RS28015
uniprot id: A0A9E6NNW9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745510:HU754 RS02150
gene id: 2745510:HU754_RS02150
uniprot id: A0A9E6NQS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

2745510:HU754 RS01725
gene id: 2745510:HU754_RS01725
uniprot id: A0A9E6NR86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

2745510:HU754 RS09375
gene id: 2745510:HU754_RS09375
uniprot id: A0A9E6NST1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

2745510:HU754 RS05600
gene id: 2745510:HU754_RS05600
uniprot id: A0A9E6NRI2
names: Subcellular Location Annotation
messages: Membrane

2745510:HU754 RS28685
gene id: 2745510:HU754_RS28685
uniprot id: A0A9E6NPY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

2745510:HU754 RS27385
gene id: 2745510:HU754_RS27385
uniprot id: A0A9E6NPH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

2745510:HU754 RS03510
gene id: 2745510:HU754_RS03510
uniprot id: A0A9E6NR15
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

2745510:HU754 RS27195
gene id: 2745510:HU754_RS27195
uniprot id: A0A9E6NPF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2745510:HU754 RS27185
gene id: 2745510:HU754_RS27185
uniprot id: A0A9E6NNL0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745510:HU754 RS25410
gene id: 2745510:HU754_RS25410
uniprot id: A0A9E6TAN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

2745510:HU754 RS23845
gene id: 2745510:HU754_RS23845
uniprot id: A0A9E6NME7
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

2745510:HU754 RS23840
gene id: 2745510:HU754_RS23840
uniprot id: A0A9E6NN61
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

2745510:HU754 RS10655
gene id: 2745510:HU754_RS10655
uniprot id: A0A9E6NTY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

2745510:HU754 RS24855
gene id: 2745510:HU754_RS24855
uniprot id: A0A9E6NP11
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

2745510:HU754 RS27655
gene id: 2745510:HU754_RS27655
uniprot id: A0A9E6TB40
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745510:HU754 RS06215
gene id: 2745510:HU754_RS06215
uniprot id: A0A9E6NSK5
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

2745510:HU754 RS02030
gene id: 2745510:HU754_RS02030
uniprot id: A0A9E6TBW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

2745510:HU754 RS07750
gene id: 2745510:HU754_RS07750
uniprot id: A0A9E6TCN1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2745510:HU754 RS06595
gene id: 2745510:HU754_RS06595
uniprot id: A0A9E6NSQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

2745510:HU754 RS24260
gene id: 2745510:HU754_RS24260
uniprot id: A0A9E6TAF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2745510:HU754 RS27035
gene id: 2745510:HU754_RS27035
uniprot id: A0A9E6NNJ0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2745510:HU754 RS27005
gene id: 2745510:HU754_RS27005
uniprot id: A0A9E6TAX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2745510:HU754 RS09440
gene id: 2745510:HU754_RS09440
uniprot id: A0A9E6NSQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

2745510:HU754 RS29640
gene id: 2745510:HU754_RS29640
uniprot id: A0A9E6NMZ4
names: Subcellular Location Annotation
messages: Cytoplasm

2745510:HU754 RS28195
gene id: 2745510:HU754_RS28195
uniprot id: A0A9E6TBF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

2745510:HU754 RS26555
gene id: 2745510:HU754_RS26555
uniprot id: A0A9E6TB26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

2745510:HU754 RS13500
gene id: 2745510:HU754_RS13500
uniprot id: A0A9E6NUC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

2745510:HU754 RS02215
gene id: 2745510:HU754_RS02215
uniprot id: A0A9E6NQY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745510:HU754 RS22665
gene id: 2745510:HU754_RS22665
uniprot id: A0A9E6NMM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2745510:HU754 RS01350
gene id: 2745510:HU754_RS01350
uniprot id: A0A9E6NQ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2745510:HU754 RS07855
gene id: 2745510:HU754_RS07855
uniprot id: A0A9E6NS63
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

2745510:HU754 RS21620
gene id: 2745510:HU754_RS21620
uniprot id: A0A9E6NLM4
names: Similarity
messages: Belongs to the BolA/IbaG family.

2745510:HU754 RS21990
gene id: 2745510:HU754_RS21990
uniprot id: A0A9E6TA84
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2745510:HU754 RS02745
gene id: 2745510:HU754_RS02745
uniprot id: A0A9E6TC52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

2745510:HU754 RS10375
gene id: 2745510:HU754_RS10375
uniprot id: A0A9E6TDJ5
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

2745510:HU754 RS09300
gene id: 2745510:HU754_RS09300
uniprot id: A0A9E6NT30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

2745510:HU754 RS19900
gene id: 2745510:HU754_RS19900
uniprot id: A0A9E6NL20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2745510:HU754 RS24345
gene id: 2745510:HU754_RS24345
uniprot id: A0A9E6TAT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

2745510:HU754 RS05275
gene id: 2745510:HU754_RS05275
uniprot id: A0A9E6NRE0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745510:HU754 RS27600
gene id: 2745510:HU754_RS27600
uniprot id: A0A9E6NNS9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

2745510:HU754 RS07385
gene id: 2745510:HU754_RS07385
uniprot id: A0A9E6NS03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

2745510:HU754 RS03835
gene id: 2745510:HU754_RS03835
uniprot id: A0A9E6TCB4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

2745510:HU754 RS28215
gene id: 2745510:HU754_RS28215
uniprot id: A0A9E6NNY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0312 family. Type 1 subfamily.
messages: Periplasm

2745510:HU754 RS24380
gene id: 2745510:HU754_RS24380
uniprot id: A0A9E6NN86
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

2745510:HU754 RS02750
gene id: 2745510:HU754_RS02750
uniprot id: A0A9E6TBU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

2745510:HU754 RS26950
gene id: 2745510:HU754_RS26950
uniprot id: A0A9E6NPA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

2745510:HU754 RS24885
gene id: 2745510:HU754_RS24885
uniprot id: A0A9E6NNK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

2745510:HU754 RS13040
gene id: 2745510:HU754_RS13040
uniprot id: A0A9E6TDR1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745510:HU754 RS18685
gene id: 2745510:HU754_RS18685
uniprot id: A0A9E6NLS3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily.
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate.
messages: Homotetramer; dimer of dimers.

2745510:HU754 RS11995
gene id: 2745510:HU754_RS11995
uniprot id: A0A9E6NUN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

2745510:HU754 RS26800
gene id: 2745510:HU754_RS26800
uniprot id: A0A9E6NP81
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

2745510:HU754 RS01380
gene id: 2745510:HU754_RS01380
uniprot id: A0A9E6TBZ6
names: Similarity
messages: Belongs to the SCO1/2 family.

2745510:HU754 RS27140
gene id: 2745510:HU754_RS27140
uniprot id: A0A9E6NNY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2745510:HU754 RS06635
gene id: 2745510:HU754_RS06635
uniprot id: A0A9E6TCG6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2745510:HU754 RS01010
gene id: 2745510:HU754_RS01010
uniprot id: A0A9E6NQI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

2745510:HU754 RS07085
gene id: 2745510:HU754_RS07085
uniprot id: A0A9E6NSS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

2745510:HU754 RS22660
gene id: 2745510:HU754_RS22660
uniprot id: A0A9E6NM48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2745510:HU754 RS00160
gene id: 2745510:HU754_RS00160
uniprot id: A0A9E6NPU6
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

2745510:HU754 RS25160
gene id: 2745510:HU754_RS25160
uniprot id: A0A9E6NMX2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

2745510:HU754 RS10150
gene id: 2745510:HU754_RS10150
uniprot id: A0A9E6NT02
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

2745510:HU754 RS19330
gene id: 2745510:HU754_RS19330
uniprot id: A0A9E6NKW0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

2745510:HU754 RS26115
gene id: 2745510:HU754_RS26115
uniprot id: A0A9E6TAZ4
names: Similarity
messages: Belongs to the histone deacetylase family.

2745510:HU754 RS28865
gene id: 2745510:HU754_RS28865
uniprot id: A0A9E6NPL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm

2745510:HU754 RS09675
gene id: 2745510:HU754_RS09675
uniprot id: A0A9E6NSX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

2745510:HU754 RS04730
gene id: 2745510:HU754_RS04730
uniprot id: A0A9E6TC59
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

2745510:HU754 RS01620
gene id: 2745510:HU754_RS01620
uniprot id: A0A9E6NR76
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745510:HU754 RS12275
gene id: 2745510:HU754_RS12275
uniprot id: A0A9E6TDV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745510:HU754 RS21335
gene id: 2745510:HU754_RS21335
uniprot id: A0A9E6TA77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

2745510:HU754 RS21860
gene id: 2745510:HU754_RS21860
uniprot id: A0A9E6NML8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745510:HU754 RS27095
gene id: 2745510:HU754_RS27095
uniprot id: A0A9E6NNL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2745510:HU754 RS13510
gene id: 2745510:HU754_RS13510
uniprot id: A0A9E6TE74
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

2745510:HU754 RS27460
gene id: 2745510:HU754_RS27460
uniprot id: A0A9E6NPI3
names: Similarity
messages: Belongs to the UPF0229 family.

2745510:HU754 RS02500
gene id: 2745510:HU754_RS02500
uniprot id: A0A9E6TBP8
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

2745510:HU754 RS24600
gene id: 2745510:HU754_RS24600
uniprot id: A0A9E6NNF6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

2745510:HU754 RS22585
gene id: 2745510:HU754_RS22585
uniprot id: A0A9E6NML4
names: Similarity
messages: Belongs to the aspartokinase family.

2745510:HU754 RS09185
gene id: 2745510:HU754_RS09185
uniprot id: A0A9E6NSL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

2745510:HU754 RS11000
gene id: 2745510:HU754_RS11000
uniprot id: A0A9E6NTF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2745510:HU754 RS17220
gene id: 2745510:HU754_RS17220
uniprot id: A0A9E6NL85
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745510:HU754 RS27105
gene id: 2745510:HU754_RS27105
uniprot id: A0A9E6NPV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2745510:HU754 RS02840
gene id: 2745510:HU754_RS02840
uniprot id: A0A9E6TC93
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

2745510:HU754 RS24620
gene id: 2745510:HU754_RS24620
uniprot id: A0A9E6NMU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

2745510:HU754 RS09600
gene id: 2745510:HU754_RS09600
uniprot id: A0A9E6NSW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

2745510:HU754 RS24755
gene id: 2745510:HU754_RS24755
uniprot id: A0A9E6NNH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745510:HU754 RS26700
gene id: 2745510:HU754_RS26700
uniprot id: A0A9E6TAV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

2745510:HU754 RS24320
gene id: 2745510:HU754_RS24320
uniprot id: A0A9E6NMZ0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

2745510:HU754 RS02270
gene id: 2745510:HU754_RS02270
uniprot id: A0A9E6TC45
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

2745510:HU754 RS00175
gene id: 2745510:HU754_RS00175
uniprot id: A0A9E6TBC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

2745510:HU754 RS02350
gene id: 2745510:HU754_RS02350
uniprot id: A0A9E6TC50
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

2745510:HU754 RS05655
gene id: 2745510:HU754_RS05655
uniprot id: A0A9E6NRE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

2745510:HU754 RS27850
gene id: 2745510:HU754_RS27850
uniprot id: A0A9E6NNY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

2745510:HU754 RS24290
gene id: 2745510:HU754_RS24290
uniprot id: A0A9E6NMJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

2745510:HU754 RS24735
gene id: 2745510:HU754_RS24735
uniprot id: A0A9E6TAK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

2745510:HU754 RS12935
gene id: 2745510:HU754_RS12935
uniprot id: A0A9E6NUR0
names: Similarity
messages: Belongs to the DapA family.

2745510:HU754 RS12080
gene id: 2745510:HU754_RS12080
uniprot id: A0A9E6NTT4
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

2745510:HU754 RS28670
gene id: 2745510:HU754_RS28670
uniprot id: A0A9E6NPW3
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

2745510:HU754 RS06240
gene id: 2745510:HU754_RS06240
uniprot id: A0A9E6NS47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AlgX family.
messages: Periplasm

2745510:HU754 RS00010
gene id: 2745510:HU754_RS00010
uniprot id: A0A9E6TBD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

2745510:HU754 RS01995
gene id: 2745510:HU754_RS01995
uniprot id: A0A9E6NQQ6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2745510:HU754 RS08315
gene id: 2745510:HU754_RS08315
uniprot id: A0A9E6NT49
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745510:HU754 RS27060
gene id: 2745510:HU754_RS27060
uniprot id: A0A9E6NNJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

2745510:HU754 RS25770
gene id: 2745510:HU754_RS25770
uniprot id: A0A9E6NPC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

2745510:HU754 RS00140
gene id: 2745510:HU754_RS00140
uniprot id: A0A9E6NPK2
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

2745510:HU754 RS09225
gene id: 2745510:HU754_RS09225
uniprot id: A0A9E6NTG6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

2745510:HU754 RS11445
gene id: 2745510:HU754_RS11445
uniprot id: A0A9E6NU87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745510:HU754 RS27065
gene id: 2745510:HU754_RS27065
uniprot id: A0A9E6NNX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2745510:HU754 RS11220
gene id: 2745510:HU754_RS11220
uniprot id: A0A9E6NU63
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745510:HU754 RS28280
gene id: 2745510:HU754_RS28280
uniprot id: A0A9E6NPS7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MdcC family.
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm
messages: Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.

2745510:HU754 RS11450
gene id: 2745510:HU754_RS11450
uniprot id: A0A9E6NU89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745510:HU754 RS21630
gene id: 2745510:HU754_RS21630
uniprot id: A0A9E6NLU2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

2745510:HU754 RS00200
gene id: 2745510:HU754_RS00200
uniprot id: A0A9E6NQR4
names: Similarity
messages: Belongs to the RutC family.

2745510:HU754 RS05360
gene id: 2745510:HU754_RS05360
uniprot id: A0A9E6NRE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2745510:HU754 RS25200
gene id: 2745510:HU754_RS25200
uniprot id: A0A9E6NNP8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

2745510:HU754 RS24240
gene id: 2745510:HU754_RS24240
uniprot id: A0A9E6NMK3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

2745510:HU754 RS00115
gene id: 2745510:HU754_RS00115
uniprot id: A0A9E6NQ74
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2745510:HU754 RS24860
gene id: 2745510:HU754_RS24860
uniprot id: A0A9E6NMR8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2745510:HU754 RS17470
gene id: 2745510:HU754_RS17470
uniprot id: A0A9E6NKA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745510:HU754 RS19550
gene id: 2745510:HU754_RS19550
uniprot id: A0A9E6T9R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

2745510:HU754 RS27015
gene id: 2745510:HU754_RS27015
uniprot id: A0A9E6TB90
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2745510:HU754 RS09820
gene id: 2745510:HU754_RS09820
uniprot id: A0A9E6NTV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

2745510:HU754 RS02490
gene id: 2745510:HU754_RS02490
uniprot id: A0A9E6TC37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

2745510:HU754 RS06355
gene id: 2745510:HU754_RS06355
uniprot id: A0A9E6NSU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745510:HU754 RS02875
gene id: 2745510:HU754_RS02875
uniprot id: A0A9E6NR13
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745510:HU754 RS24800
gene id: 2745510:HU754_RS24800
uniprot id: A0A9E6NNJ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

2745510:HU754 RS12770
gene id: 2745510:HU754_RS12770
uniprot id: A0A9E6NUZ6
names: Similarity
messages: Belongs to the SCO1/2 family.

2745510:HU754 RS11455
gene id: 2745510:HU754_RS11455
uniprot id: A0A9E6NTL0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745510:HU754 RS22435
gene id: 2745510:HU754_RS22435
uniprot id: A0A9E6NN47
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2745510:HU754 RS23825
gene id: 2745510:HU754_RS23825
uniprot id: A0A9E6NN99
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

2745510:HU754 RS23200
gene id: 2745510:HU754_RS23200
uniprot id: A0A9E6NN09
names: Subcellular Location Annotation
messages: Cytoplasm

2745510:HU754 RS23265
gene id: 2745510:HU754_RS23265
uniprot id: A0A9E6TAG4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

2745510:HU754 RS17205
gene id: 2745510:HU754_RS17205
uniprot id: A0A9E6T9C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

2745510:HU754 RS26750
gene id: 2745510:HU754_RS26750
uniprot id: A0A9E6NP31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2745510:HU754 RS06620
gene id: 2745510:HU754_RS06620
uniprot id: A0A9E6NS96
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

2745510:HU754 RS07430
gene id: 2745510:HU754_RS07430
uniprot id: A0A9E6TCL2
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

2745510:HU754 RS01420
gene id: 2745510:HU754_RS01420
uniprot id: A0A9E6NQS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

2745510:HU754 RS16140
gene id: 2745510:HU754_RS16140
uniprot id: A0A9E6T9A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

2745510:HU754 RS10755
gene id: 2745510:HU754_RS10755
uniprot id: A0A9E6TDP1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

2745510:HU754 RS05240
gene id: 2745510:HU754_RS05240
uniprot id: A0A9E6TCK7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

2745510:HU754 RS11200
gene id: 2745510:HU754_RS11200
uniprot id: A0A9E6NUM7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745510:HU754 RS07645
gene id: 2745510:HU754_RS07645
uniprot id: A0A9E6NSZ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

2745510:HU754 RS28465
gene id: 2745510:HU754_RS28465
uniprot id: A0A9E6NPY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

2745510:HU754 RS27075
gene id: 2745510:HU754_RS27075
uniprot id: A0A9E6TB06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2745510:HU754 RS08690
gene id: 2745510:HU754_RS08690
uniprot id: A0A9E6TD88
names: Similarity
messages: Belongs to the DEAD box helicase family.

2745510:HU754 RS22970
gene id: 2745510:HU754_RS22970
uniprot id: A0A9E6NM87
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

2745510:HU754 RS07185
gene id: 2745510:HU754_RS07185
uniprot id: A0A9E6NSG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

2745510:HU754 RS11520
gene id: 2745510:HU754_RS11520
uniprot id: A0A9E6NU97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

2745510:HU754 RS10030
gene id: 2745510:HU754_RS10030
uniprot id: A0A9E6TDK5
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

2745510:HU754 RS27100
gene id: 2745510:HU754_RS27100
uniprot id: A0A9E6NPC4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2745510:HU754 RS07525
gene id: 2745510:HU754_RS07525
uniprot id: A0A9E6TD47
names: Subcellular Location Annotation
messages: Cytoplasm

2745510:HU754 RS09435
gene id: 2745510:HU754_RS09435
uniprot id: A0A9E6NTZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

2745510:HU754 RS00960
gene id: 2745510:HU754_RS00960
uniprot id: A0A9E6TBT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

2745510:HU754 RS27025
gene id: 2745510:HU754_RS27025
uniprot id: A0A9E6NPB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2745510:HU754 RS01005
gene id: 2745510:HU754_RS01005
uniprot id: A0A9E6NPQ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

2745510:HU754 RS11475
gene id: 2745510:HU754_RS11475
uniprot id: A0A9E6TD78
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

2745510:HU754 RS24900
gene id: 2745510:HU754_RS24900
uniprot id: A0A9E6NN65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

2745510:HU754 RS27145
gene id: 2745510:HU754_RS27145
uniprot id: A0A9E6TB66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2745510:HU754 RS24790
gene id: 2745510:HU754_RS24790
uniprot id: A0A9E6NNG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2745510:HU754 RS23210
gene id: 2745510:HU754_RS23210
uniprot id: A0A9E6NMU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

2745510:HU754 RS03215
gene id: 2745510:HU754_RS03215
uniprot id: A0A9E6TBW9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

2745510:HU754 RS00950
gene id: 2745510:HU754_RS00950
uniprot id: A0A9E6NPR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

2745510:HU754 RS21090
gene id: 2745510:HU754_RS21090
uniprot id: A0A9E6NLH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

2745510:HU754 RS19400
gene id: 2745510:HU754_RS19400
uniprot id: A0A9E6NM29
names: Similarity
messages: Belongs to the asparaginase 1 family.

2745510:HU754 RS05685
gene id: 2745510:HU754_RS05685
uniprot id: A0A9E6NRV6
names: Similarity
messages: Belongs to the UPF0307 family.

2745510:HU754 RS12280
gene id: 2745510:HU754_RS12280
uniprot id: A0A9E6NTQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745510:HU754 RS23255
gene id: 2745510:HU754_RS23255
uniprot id: A0A9E6TA91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2745510:HU754 RS13225
gene id: 2745510:HU754_RS13225
uniprot id: A0A9E6NU05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745510:HU754 RS27155
gene id: 2745510:HU754_RS27155
uniprot id: A0A9E6TAY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2745510:HU754 RS27160
gene id: 2745510:HU754_RS27160
uniprot id: A0A9E6TB63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2745510:HU754 RS23060
gene id: 2745510:HU754_RS23060
uniprot id: A0A9E6NMW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745510:HU754 RS20890
gene id: 2745510:HU754_RS20890
uniprot id: A0A9E6NLC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2745510:HU754 RS25820
gene id: 2745510:HU754_RS25820
uniprot id: A0A9E6TAQ6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

2745510:HU754 RS07765
gene id: 2745510:HU754_RS07765
uniprot id: A0A9E6NS29
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745510:HU754 RS11485
gene id: 2745510:HU754_RS11485
uniprot id: A0A9E6TDQ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745510:HU754 RS01605
gene id: 2745510:HU754_RS01605
uniprot id: A0A9E6TC09
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

2745510:HU754 RS28355
gene id: 2745510:HU754_RS28355
uniprot id: A0A9E6NPT4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

2745510:HU754 RS22440
gene id: 2745510:HU754_RS22440
uniprot id: A0A9E6NLW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

2745510:HU754 RS06270
gene id: 2745510:HU754_RS06270
uniprot id: A0A9E6NRL1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

2745510:HU754 RS20635
gene id: 2745510:HU754_RS20635
uniprot id: A0A9E6NM27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

2745510:HU754 RS22550
gene id: 2745510:HU754_RS22550
uniprot id: A0A9E6NLX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

2745510:HU754 RS17110
gene id: 2745510:HU754_RS17110
uniprot id: A0A9E6NK42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

2745510:HU754 RS09560
gene id: 2745510:HU754_RS09560
uniprot id: A0A9E6TCV8
names: Similarity
messages: Belongs to the MlaA family.

2745510:HU754 RS21970
gene id: 2745510:HU754_RS21970
uniprot id: A0A9E6TAB7
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

2745510:HU754 RS15390
gene id: 2745510:HU754_RS15390
uniprot id: A0A9E6NKK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnF family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

2745510:HU754 RS15295
gene id: 2745510:HU754_RS15295
uniprot id: A0A9E6T911
names: Similarity
messages: Belongs to the glutamine synthetase family.

2745510:HU754 RS19950
gene id: 2745510:HU754_RS19950
uniprot id: A0A9E6NL22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

2745510:HU754 RS27020
gene id: 2745510:HU754_RS27020
uniprot id: A0A9E6NNK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2745510:HU754 RS27000
gene id: 2745510:HU754_RS27000
uniprot id: A0A9E6TB01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

2745510:HU754 RS24770
gene id: 2745510:HU754_RS24770
uniprot id: A0A9E6NMQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

2745510:HU754 RS00500
gene id: 2745510:HU754_RS00500
uniprot id: A0A9E6TBG1
names: Subcellular Location Annotation
messages: Membrane

2745510:HU754 RS03540
gene id: 2745510:HU754_RS03540
uniprot id: A0A9E6NQL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2745510:HU754 RS02010
gene id: 2745510:HU754_RS02010
uniprot id: A0A9E6NQI1
names: Subcellular Location Annotation
messages: Membrane

2745510:HU754 RS07570
gene id: 2745510:HU754_RS07570
uniprot id: A0A9E6NSA4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2745510:HU754 RS09045
gene id: 2745510:HU754_RS09045
uniprot id: A0A9E6NSL1
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

2745510:HU754 RS25945
gene id: 2745510:HU754_RS25945
uniprot id: A0A9E6NNZ9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

2745510:HU754 RS13785
gene id: 2745510:HU754_RS13785
uniprot id: A0A9E6TDV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745510:HU754 RS18545
gene id: 2745510:HU754_RS18545
uniprot id: A0A9E6NL87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP.
messages: Membrane

2745510:HU754 RS27610
gene id: 2745510:HU754_RS27610
uniprot id: A0A9E6NQ18
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

2745510:HU754 RS08790
gene id: 2745510:HU754_RS08790
uniprot id: A0A9E6NTB4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745510:HU754 RS28985
gene id: 2745510:HU754_RS28985
uniprot id: A0A9E6NP91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

2745510:HU754 RS20590
gene id: 2745510:HU754_RS20590
uniprot id: A0A9E6NM04
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745510:HU754 RS08250
gene id: 2745510:HU754_RS08250
uniprot id: A0A9E6NSA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

2745510:HU754 RS01035
gene id: 2745510:HU754_RS01035
uniprot id: A0A9E6NPR9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2745510:HU754 RS05320
gene id: 2745510:HU754_RS05320
uniprot id: A0A9E6TCR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745510:HU754 RS06430
gene id: 2745510:HU754_RS06430
uniprot id: A0A9E6NSV9
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

2745510:HU754 RS28190
gene id: 2745510:HU754_RS28190
uniprot id: A0A9E6TBD0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

2745510:HU754 RS02165
gene id: 2745510:HU754_RS02165
uniprot id: A0A9E6NQJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

2745510:HU754 RS27180
gene id: 2745510:HU754_RS27180
uniprot id: A0A9E6NPW6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

2745510:HU754 RS11005
gene id: 2745510:HU754_RS11005
uniprot id: A0A9E6NTS2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2745510:HU754 RS10200
gene id: 2745510:HU754_RS10200
uniprot id: A0A9E6TDF3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

2745510:HU754 RS02615
gene id: 2745510:HU754_RS02615
uniprot id: A0A9E6NRJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745510:HU754 RS00710
gene id: 2745510:HU754_RS00710
uniprot id: A0A9E6NQ95
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

2745510:HU754 RS28715
gene id: 2745510:HU754_RS28715
uniprot id: A0A9E6TBL9
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

2745510:HU754 RS07550
gene id: 2745510:HU754_RS07550
uniprot id: A0A9E6NT42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745510:HU754 RS02980
gene id: 2745510:HU754_RS02980
uniprot id: A0A9E6TBV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. OpgH subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
messages: Membrane

2745510:HU754 RS07920
gene id: 2745510:HU754_RS07920
uniprot id: A0A9E6NSZ8
names: Subcellular Location Annotation
messages: Membrane

2745510:HU754 RS01315
gene id: 2745510:HU754_RS01315
uniprot id: A0A9E6NR42
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

2745510:HU754 RS10645
gene id: 2745510:HU754_RS10645
uniprot id: A0A9E6NU50
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

2745510:HU754 RS07030
gene id: 2745510:HU754_RS07030
uniprot id: A0A9E6TCK2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

2745510:HU754 RS24335
gene id: 2745510:HU754_RS24335
uniprot id: A0A9E6TAG0
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

2745510:HU754 RS08335
gene id: 2745510:HU754_RS08335
uniprot id: A0A9E6NSF1
names: Function
messages: Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions.

2745510:HU754 RS00685
gene id: 2745510:HU754_RS00685
uniprot id: A0A9E6NQE1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

2745510:HU754 RS26780
gene id: 2745510:HU754_RS26780
uniprot id: A0A9E6TAV9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

2745510:HU754 RS19495
gene id: 2745510:HU754_RS19495
uniprot id: A0A9E6NLP2
names: Subcellular Location Annotation
messages: Membrane

2745510:HU754 RS05350
gene id: 2745510:HU754_RS05350
uniprot id: A0A9E6NRA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

2745510:HU754 RS01305
gene id: 2745510:HU754_RS01305
uniprot id: A0A9E6NPU2
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

2745510:HU754 RS01050
gene id: 2745510:HU754_RS01050
uniprot id: A0A9E6TBJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

2745510:HU754 RS19535
gene id: 2745510:HU754_RS19535
uniprot id: A0A9E6NKY4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745510:HU754 RS01525
gene id: 2745510:HU754_RS01525
uniprot id: A0A9E6TBT4
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

2745510:HU754 RS21260
gene id: 2745510:HU754_RS21260
uniprot id: A0A9E6TA21
names: Similarity
messages: Belongs to the universal stress protein A family.

2745510:HU754 RS25505
gene id: 2745510:HU754_RS25505
uniprot id: A0A9E6NNR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

2745510:HU754 RS10490
gene id: 2745510:HU754_RS10490
uniprot id: A0A9E6NU33
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

2745510:HU754 RS27085
gene id: 2745510:HU754_RS27085
uniprot id: A0A9E6TB58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2745510:HU754 RS23330
gene id: 2745510:HU754_RS23330
uniprot id: A0A9E6TA95
names: Similarity
messages: Belongs to the UPF0234 family.

2745510:HU754 RS05250
gene id: 2745510:HU754_RS05250
uniprot id: A0A9E6NR94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

2745510:HU754 RS27130
gene id: 2745510:HU754_RS27130
uniprot id: A0A9E6NPF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2745510:HU754 RS24300
gene id: 2745510:HU754_RS24300
uniprot id: A0A9E6NMQ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

2745510:HU754 RS00965
gene id: 2745510:HU754_RS00965
uniprot id: A0A9E6TBJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

2745510:HU754 RS19800
gene id: 2745510:HU754_RS19800
uniprot id: A0A9E6NLW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

2745510:HU754 RS08900
gene id: 2745510:HU754_RS08900
uniprot id: A0A9E6NT00
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

2745510:HU754 RS03160
gene id: 2745510:HU754_RS03160
uniprot id: A0A9E6NR99
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

2745510:HU754 RS26990
gene id: 2745510:HU754_RS26990
uniprot id: A0A9E6NNW8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2745510:HU754 RS28780
gene id: 2745510:HU754_RS28780
uniprot id: A0A9E6NQ24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

2745510:HU754 RS20685
gene id: 2745510:HU754_RS20685
uniprot id: A0A9E6T9Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Sulfur carrier protein which probably makes part of a sulfur-relay system.

2745510:HU754 RS05280
gene id: 2745510:HU754_RS05280
uniprot id: A0A9E6NRQ3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

2745510:HU754 RS23405
gene id: 2745510:HU754_RS23405
uniprot id: A0A9E6TAA2
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

2745510:HU754 RS19670
gene id: 2745510:HU754_RS19670
uniprot id: A0A9E6T9T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

2745510:HU754 RS29275
gene id: 2745510:HU754_RS29275
uniprot id: A0A9E6TBJ9
names: Similarity
messages: Belongs to the P(II) protein family.

2745510:HU754 RS01340
gene id: 2745510:HU754_RS01340
uniprot id: A0A9E6NQR5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

2745510:HU754 RS10535
gene id: 2745510:HU754_RS10535
uniprot id: A0A9E6TDI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

2745510:HU754 RS09980
gene id: 2745510:HU754_RS09980
uniprot id: A0A9E6NSW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745510:HU754 RS27170
gene id: 2745510:HU754_RS27170
uniprot id: A0A9E6NNM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

2745510:HU754 RS27045
gene id: 2745510:HU754_RS27045
uniprot id: A0A9E6NNP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

2745510:HU754 RS07865
gene id: 2745510:HU754_RS07865
uniprot id: A0A9E6NS90
names: Subcellular Location Annotation
messages: Membrane

2745510:HU754 RS09445
gene id: 2745510:HU754_RS09445
uniprot id: A0A9E6NTQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

2745510:HU754 RS07090
gene id: 2745510:HU754_RS07090
uniprot id: A0A9E6NS43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

2745510:HU754 RS11560
gene id: 2745510:HU754_RS11560
uniprot id: A0A9E6TDR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2745510:HU754 RS02365
gene id: 2745510:HU754_RS02365
uniprot id: A0A9E6NQZ8
names: Similarity
messages: Belongs to the HSP15 family.

2745510:HU754 RS04345
gene id: 2745510:HU754_RS04345
uniprot id: A0A9E6TCE3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

2745510:HU754 RS01300
gene id: 2745510:HU754_RS01300
uniprot id: A0A9E6TBZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

2745510:HU754 RS02850
gene id: 2745510:HU754_RS02850
uniprot id: A0A9E6NR57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

2745510:HU754 RS23160
gene id: 2745510:HU754_RS23160
uniprot id: A0A9E6TAE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

2745510:HU754 RS27120
gene id: 2745510:HU754_RS27120
uniprot id: A0A9E6NNQ0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2745510:HU754 RS25830
gene id: 2745510:HU754_RS25830
uniprot id: A0A9E6TB17
names: Similarity
messages: Belongs to the YjdM family.

2745510:HU754 RS27115
gene id: 2745510:HU754_RS27115
uniprot id: A0A9E6NPE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

2745510:HU754 RS05805
gene id: 2745510:HU754_RS05805
uniprot id: A0A9E6NRF7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

2745510:HU754 RS06050
gene id: 2745510:HU754_RS06050
uniprot id: A0A9E6NS97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

2745510:HU754 RS21005
gene id: 2745510:HU754_RS21005
uniprot id: A0A9E6NLF8
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

2745510:HU754 RS27050
gene id: 2745510:HU754_RS27050
uniprot id: A0A9E6NP62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2745510:HU754 RS23045
gene id: 2745510:HU754_RS23045
uniprot id: A0A9E6NMZ3
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

2745510:HU754 RS11310
gene id: 2745510:HU754_RS11310
uniprot id: A0A9E6NTW7
names: Subcellular Location Annotation
messages: Membrane

2745510:HU754 RS08665
gene id: 2745510:HU754_RS08665
uniprot id: A0A9E6NSN4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745510:HU754 RS28840
gene id: 2745510:HU754_RS28840
uniprot id: A0A9E6NQ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

2745510:HU754 RS10035
gene id: 2745510:HU754_RS10035
uniprot id: A0A9E6TD48
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

2745510:HU754 RS04205
gene id: 2745510:HU754_RS04205
uniprot id: A0A9E6TC34
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2745510:HU754 RS28105
gene id: 2745510:HU754_RS28105
uniprot id: A0A9E6TB70
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

2745510:HU754 RS27985
gene id: 2745510:HU754_RS27985
uniprot id: A0A9E6NQ70
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

2745510:HU754 RS10130
gene id: 2745510:HU754_RS10130
uniprot id: A0A9E6TDI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

2745510:HU754 RS22035
gene id: 2745510:HU754_RS22035
uniprot id: A0A9E6NLT6
names: Similarity
messages: Belongs to the UPF0434 family.

2745510:HU754 RS08345
gene id: 2745510:HU754_RS08345
uniprot id: A0A9E6NT70
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

2745510:HU754 RS26530
gene id: 2745510:HU754_RS26530
uniprot id: A0A9E6NNQ8
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

2745510:HU754 RS19340
gene id: 2745510:HU754_RS19340
uniprot id: A0A9E6NL23
names: Subcellular Location Annotation
messages: Cytoplasm

2745510:HU754 RS21550
gene id: 2745510:HU754_RS21550
uniprot id: A0A9E6NLT0
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

2745510:HU754 RS12625
gene id: 2745510:HU754_RS12625
uniprot id: A0A9E6NU06
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

2745510:HU754 RS12640
gene id: 2745510:HU754_RS12640
uniprot id: A0A9E6NU02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745510:HU754 RS25325
gene id: 2745510:HU754_RS25325
uniprot id: A0A9E6NNP0
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

2745510:HU754 RS24605
gene id: 2745510:HU754_RS24605
uniprot id: A0A9E6NNX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

2745510:HU754 RS27480
gene id: 2745510:HU754_RS27480
uniprot id: A0A9E6NNP6
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

2745510:HU754 RS27275
gene id: 2745510:HU754_RS27275
uniprot id: A0A9E6TAZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

2745510:HU754 RS01020
gene id: 2745510:HU754_RS01020
uniprot id: A0A9E6NQE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

2745510:HU754 RS23280
gene id: 2745510:HU754_RS23280
uniprot id: A0A9E6NNE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

2745510:HU754 RS23805
gene id: 2745510:HU754_RS23805
uniprot id: A0A9E6NMD9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

2745510:HU754 RS29240
gene id: 2745510:HU754_RS29240
uniprot id: A0A9E6NPZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

2745510:HU754 RS19540
gene id: 2745510:HU754_RS19540
uniprot id: A0A9E6NL83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

2745510:HU754 RS14315
gene id: 2745510:HU754_RS14315
uniprot id: A0A9E6NUL7
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

2745510:HU754 RS07040
gene id: 2745510:HU754_RS07040
uniprot id: A0A9E6TCU9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745510:HU754 RS27685
gene id: 2745510:HU754_RS27685
uniprot id: A0A9E6NQ25
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

2745510:HU754 RS09885
gene id: 2745510:HU754_RS09885
uniprot id: A0A9E6NSV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

2745510:HU754 RS23930
gene id: 2745510:HU754_RS23930
uniprot id: A0A9E6TAM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745510:HU754 RS23300
gene id: 2745510:HU754_RS23300
uniprot id: A0A9E6NMV3
names: Similarity
messages: Belongs to the Dps family.

2745510:HU754 RS06565
gene id: 2745510:HU754_RS06565
uniprot id: A0A9E6TCS1
names: Similarity
messages: Belongs to the YkuD family.

2745510:HU754 RS19320
gene id: 2745510:HU754_RS19320
uniprot id: A0A9E6NM20
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2745510:HU754 RS24165
gene id: 2745510:HU754_RS24165
uniprot id: A0A9E6NMW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

2745510:HU754 RS26690
gene id: 2745510:HU754_RS26690
uniprot id: A0A9E6TB29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

2745510:HU754 RS06760
gene id: 2745510:HU754_RS06760
uniprot id: A0A9E6NSS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745510:HU754 RS07820
gene id: 2745510:HU754_RS07820
uniprot id: A0A9E6TCQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

2745510:HU754 RS25695
gene id: 2745510:HU754_RS25695
uniprot id: A0A9E6NN17
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2745510:HU754 RS22360
gene id: 2745510:HU754_RS22360
uniprot id: A0A9E6NN35
names: Subcellular Location Annotation
messages: Membrane

2745510:HU754 RS24350
gene id: 2745510:HU754_RS24350
uniprot id: A0A9E6NML6
names: Similarity
messages: Belongs to the HesB/IscA family.

2745510:HU754 RS00515
gene id: 2745510:HU754_RS00515
uniprot id: A0A9E6TBU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

2745510:HU754 RS18245
gene id: 2745510:HU754_RS18245
uniprot id: A0A9E6T9E4
names: Subcellular Location Annotation
messages: Membrane

2745510:HU754 RS11440
gene id: 2745510:HU754_RS11440
uniprot id: A0A9E6NTL3
names: Subcellular Location Annotation
messages: Membrane

2745510:HU754 RS21945
gene id: 2745510:HU754_RS21945
uniprot id: A0A9E6NMF6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2745510:HU754 RS12295
gene id: 2745510:HU754_RS12295
uniprot id: A0A9E6NTN5
names: Similarity
messages: Belongs to the glutamine synthetase family.

2745510:HU754 RS07125
gene id: 2745510:HU754_RS07125
uniprot id: A0A9E6TD28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

2745510:HU754 RS29315
gene id: 2745510:HU754_RS29315
uniprot id: A0A9E6NQ02
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745510:HU754 RS16865
gene id: 2745510:HU754_RS16865
uniprot id: A0A9E6T9D6
names: Subcellular Location Annotation
messages: Membrane

2745510:HU754 RS27580
gene id: 2745510:HU754_RS27580
uniprot id: A0A9E6TEH3
names: Function
names: Similarity
messages: Belongs to the PqqA family.
messages: Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.

2745510:HU754 RS05335
gene id: 2745510:HU754_RS05335
uniprot id: A0A9E6NRA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

2745510:HU754 RS08785
gene id: 2745510:HU754_RS08785
uniprot id: A0A9E6NSG7
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

2745510:HU754 RS19310
gene id: 2745510:HU754_RS19310
uniprot id: A0A9E6NKU8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2745510:HU754 RS21285
gene id: 2745510:HU754_RS21285
uniprot id: A0A9E6NMA2
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

2745510:HU754 RS15775
gene id: 2745510:HU754_RS15775
uniprot id: A0A9E6NKB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

2745510:HU754 RS25335
gene id: 2745510:HU754_RS25335
uniprot id: A0A9E6NMX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745510:HU754 RS19510
gene id: 2745510:HU754_RS19510
uniprot id: A0A9E6NLT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

2745510:HU754 RS25055
gene id: 2745510:HU754_RS25055
uniprot id: A0A9E6NN82
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

2745510:HU754 RS28340
gene id: 2745510:HU754_RS28340
uniprot id: A0A9E6TBD7
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

2745510:HU754 RS09640
gene id: 2745510:HU754_RS09640
uniprot id: A0A9E6TDC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

2745510:HU754 RS28655
gene id: 2745510:HU754_RS28655
uniprot id: A0A9E6TBG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2745510:HU754 RS24325
gene id: 2745510:HU754_RS24325
uniprot id: A0A9E6TAP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

2745510:HU754 RS00565
gene id: 2745510:HU754_RS00565
uniprot id: A0A9E6NQG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

2745510:HU754 RS11430
gene id: 2745510:HU754_RS11430
uniprot id: A0A9E6NTE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745510:HU754 RS00955
gene id: 2745510:HU754_RS00955
uniprot id: A0A9E6NQ43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

2745510:HU754 RS16650
gene id: 2745510:HU754_RS16650
uniprot id: A0A9E6NJZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

2745510:HU754 RS19520
gene id: 2745510:HU754_RS19520
uniprot id: A0A9E6TED5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745510:HU754 RS03655
gene id: 2745510:HU754_RS03655
uniprot id: A0A9E6NQN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

2745510:HU754 RS10230
gene id: 2745510:HU754_RS10230
uniprot id: A0A9E6NU04
names: Subcellular Location Annotation
messages: Membrane

2745510:HU754 RS08950
gene id: 2745510:HU754_RS08950
uniprot id: A0A9E6NTD1
names: Similarity
messages: Belongs to the YciI family.

2745510:HU754 RS02635
gene id: 2745510:HU754_RS02635
uniprot id: A0A9E6NQY7
names: Subcellular Location Annotation
messages: Membrane

2745510:HU754 RS22580
gene id: 2745510:HU754_RS22580
uniprot id: A0A9E6NM38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

2745510:HU754 RS23275
gene id: 2745510:HU754_RS23275
uniprot id: A0A9E6NMY7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

2745510:HU754 RS05640
gene id: 2745510:HU754_RS05640
uniprot id: A0A9E6TCM3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

2745510:HU754 RS27055
gene id: 2745510:HU754_RS27055
uniprot id: A0A9E6NPD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2745510:HU754 RS00490
gene id: 2745510:HU754_RS00490
uniprot id: A0A9E6NPY5
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

2745510:HU754 RS23270
gene id: 2745510:HU754_RS23270
uniprot id: A0A9E6NM68
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

2745510:HU754 RS01030
gene id: 2745510:HU754_RS01030
uniprot id: A0A9E6TEE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

2745510:HU754 RS01045
gene id: 2745510:HU754_RS01045
uniprot id: A0A9E6TBT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

2745510:HU754 RS09065
gene id: 2745510:HU754_RS09065
uniprot id: A0A9E6NTF0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2745510:HU754 RS26965
gene id: 2745510:HU754_RS26965
uniprot id: A0A9E6NPC1
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

2745510:HU754 RS11595
gene id: 2745510:HU754_RS11595
uniprot id: A0A9E6NUA7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

2745510:HU754 RS23505
gene id: 2745510:HU754_RS23505
uniprot id: A0A9E6NN14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

2745510:HU754 RS11490
gene id: 2745510:HU754_RS11490
uniprot id: A0A9E6NTG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745510:HU754 RS10635
gene id: 2745510:HU754_RS10635
uniprot id: A0A9E6NUE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

2745510:HU754 RS02330
gene id: 2745510:HU754_RS02330
uniprot id: A0A9E6TC27
names: Similarity
messages: Belongs to the thioesterase PaaI family.

2745510:HU754 RS29025
gene id: 2745510:HU754_RS29025
uniprot id: A0A9E6NPA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

2745510:HU754 RS03020
gene id: 2745510:HU754_RS03020
uniprot id: A0A9E6NQG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2745510:HU754 RS05300
gene id: 2745510:HU754_RS05300
uniprot id: A0A9E6TCJ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745510:HU754 RS06220
gene id: 2745510:HU754_RS06220
uniprot id: A0A9E6NRP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AlgF family.
messages: Periplasm

2745510:HU754 RS16215
gene id: 2745510:HU754_RS16215
uniprot id: A0A9E6T941
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

2745510:HU754 RS04240
gene id: 2745510:HU754_RS04240
uniprot id: A0A9E6NRV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

2745510:HU754 RS27110
gene id: 2745510:HU754_RS27110
uniprot id: A0A9E6NNJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2745510:HU754 RS22675
gene id: 2745510:HU754_RS22675
uniprot id: A0A9E6NLZ6
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

2745510:HU754 RS09735
gene id: 2745510:HU754_RS09735
uniprot id: A0A9E6NU39
names: Similarity
messages: Belongs to the peptidase C40 family.

2745510:HU754 RS21180
gene id: 2745510:HU754_RS21180
uniprot id: A0A9E6TA16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

2745510:HU754 RS24355
gene id: 2745510:HU754_RS24355
uniprot id: A0A9E6NNC4
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

2745510:HU754 RS06655
gene id: 2745510:HU754_RS06655
uniprot id: A0A9E6NSI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

2745510:HU754 RS23670
gene id: 2745510:HU754_RS23670
uniprot id: A0A9E6NMB2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

2745510:HU754 RS28650
gene id: 2745510:HU754_RS28650
uniprot id: A0A9E6TB79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

2745510:HU754 RS19490
gene id: 2745510:HU754_RS19490
uniprot id: A0A9E6NKW5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745510:HU754 RS03425
gene id: 2745510:HU754_RS03425
uniprot id: A0A9E6NRG4
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

2745510:HU754 RS27135
gene id: 2745510:HU754_RS27135
uniprot id: A0A9E6NNK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

2745510:HU754 RS22255
gene id: 2745510:HU754_RS22255
uniprot id: A0A9E6TA99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

2745510:HU754 RS05515
gene id: 2745510:HU754_RS05515
uniprot id: A0A9E6NRC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2745510:HU754 RS05775
gene id: 2745510:HU754_RS05775
uniprot id: A0A9E6NRY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

2745510:HU754 RS02820
gene id: 2745510:HU754_RS02820
uniprot id: A0A9E6TC56
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

2745510:HU754 RS11015
gene id: 2745510:HU754_RS11015
uniprot id: A0A9E6TDE5
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

2745510:HU754 RS07770
gene id: 2745510:HU754_RS07770
uniprot id: A0A9E6NSX6
names: Similarity
messages: Belongs to the leucine-binding protein family.

2745510:HU754 RS25790
gene id: 2745510:HU754_RS25790
uniprot id: A0A9E6NNS5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

2745510:HU754 RS23855
gene id: 2745510:HU754_RS23855
uniprot id: A0A9E6TAL8
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

2745510:HU754 RS08395
gene id: 2745510:HU754_RS08395
uniprot id: A0A9E6NT64
names: Similarity
messages: Belongs to the UPF0339 family. Duplicated subfamily.

2745510:HU754 RS13960
gene id: 2745510:HU754_RS13960
uniprot id: A0A9E6TDL1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2745510:HU754 RS02730
gene id: 2745510:HU754_RS02730
uniprot id: A0A9E6NR78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

2745510:HU754 RS07170
gene id: 2745510:HU754_RS07170
uniprot id: A0A9E6NS52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

2745510:HU754 RS03690
gene id: 2745510:HU754_RS03690
uniprot id: A0A9E6NQN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

2745510:HU754 RS27125
gene id: 2745510:HU754_RS27125
uniprot id: A0A9E6NP72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2745510:HU754 RS10040
gene id: 2745510:HU754_RS10040
uniprot id: A0A9E6TCY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

2745510:HU754 RS05465
gene id: 2745510:HU754_RS05465
uniprot id: A0A9E6NRU1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2745510:HU754 RS20605
gene id: 2745510:HU754_RS20605
uniprot id: A0A9E6TA33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

2745510:HU754 RS25850
gene id: 2745510:HU754_RS25850
uniprot id: A0A9E6NN38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

2745510:HU754 RS05245
gene id: 2745510:HU754_RS05245
uniprot id: A0A9E6TCR3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

2745510:HU754 RS09050
gene id: 2745510:HU754_RS09050
uniprot id: A0A9E6NTL1
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

2745510:HU754 RS00970
gene id: 2745510:HU754_RS00970
uniprot id: A0A9E6TBH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

2745510:HU754 RS03820
gene id: 2745510:HU754_RS03820
uniprot id: A0A9E6NRM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

2745510:HU754 RS27280
gene id: 2745510:HU754_RS27280
uniprot id: A0A9E6TB67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

2745510:HU754 RS21950
gene id: 2745510:HU754_RS21950
uniprot id: A0A9E6NMH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

2745510:HU754 RS24305
gene id: 2745510:HU754_RS24305
uniprot id: A0A9E6NN81
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

2745510:HU754 RS25170
gene id: 2745510:HU754_RS25170
uniprot id: A0A9E6NP45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

2745510:HU754 RS21360
gene id: 2745510:HU754_RS21360
uniprot id: A0A9E6NLI0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

2745510:HU754 RS24410
gene id: 2745510:HU754_RS24410
uniprot id: A0A9E6TAG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

2745510:HU754 RS03770
gene id: 2745510:HU754_RS03770
uniprot id: A0A9E6TCF0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

2745510:HU754 RS03045
gene id: 2745510:HU754_RS03045
uniprot id: A0A9E6NQF3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

2745510:HU754 RS03030
gene id: 2745510:HU754_RS03030
uniprot id: A0A9E6NQL1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

2745510:HU754 RS02970
gene id: 2745510:HU754_RS02970
uniprot id: A0A9E6NQT8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

2745510:HU754 RS02380
gene id: 2745510:HU754_RS02380
uniprot id: A0A9E6NR08
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2745510:HU754 RS06470
gene id: 2745510:HU754_RS06470
uniprot id: A0A9E6TCS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

2745510:HU754 RS26650
gene id: 2745510:HU754_RS26650
uniprot id: A0A9E6NPN6
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.

2745510:HU754 RS01370
gene id: 2745510:HU754_RS01370
uniprot id: A0A9E6TBI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745510:HU754 RS00230
gene id: 2745510:HU754_RS00230
uniprot id: A0A9E6NPG9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745510:HU754 RS28365
gene id: 2745510:HU754_RS28365
uniprot id: A0A9E6NP00
names: Subcellular Location Annotation
messages: Membrane

2745510:HU754 RS25415
gene id: 2745510:HU754_RS25415
uniprot id: A0A9E6TAV3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745510:HU754 RS27175
gene id: 2745510:HU754_RS27175
uniprot id: A0A9E6NPD2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2745510:HU754 RS26995
gene id: 2745510:HU754_RS26995
uniprot id: A0A9E6TB49
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2745510:HU754 RS05865
gene id: 2745510:HU754_RS05865
uniprot id: A0A9E6TCC0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2745510:HU754 RS21150
gene id: 2745510:HU754_RS21150
uniprot id: A0A9E6NLN5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

2745510:HU754 RS29250
gene id: 2745510:HU754_RS29250
uniprot id: A0A9E6NPD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

2745510:HU754 RS05070
gene id: 2745510:HU754_RS05070
uniprot id: A0A9E6TC77
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

2745510:HU754 RS02795
gene id: 2745510:HU754_RS02795
uniprot id: A0A9E6NQH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

2745510:HU754 RS21235
gene id: 2745510:HU754_RS21235
uniprot id: A0A9E6NM71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745510:HU754 RS22650
gene id: 2745510:HU754_RS22650
uniprot id: A0A9E6NLY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745510:HU754 RS26710
gene id: 2745510:HU754_RS26710
uniprot id: A0A9E6TB73
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

2745510:HU754 RS27270
gene id: 2745510:HU754_RS27270
uniprot id: A0A9E6TB16
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

2745510:HU754 RS03750
gene id: 2745510:HU754_RS03750
uniprot id: A0A9E6TCB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

2745510:HU754 RS21965
gene id: 2745510:HU754_RS21965
uniprot id: A0A9E6NM35
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2745510:HU754 RS13505
gene id: 2745510:HU754_RS13505
uniprot id: A0A9E6NUR9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

2745510:HU754 RS00005
gene id: 2745510:HU754_RS00005
uniprot id: A0A9E6TBQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

2745510:HU754 RS29065
gene id: 2745510:HU754_RS29065
uniprot id: A0A9E6NQ21
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

2745510:HU754 RS11540
gene id: 2745510:HU754_RS11540
uniprot id: A0A9E6TDU5
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

2745510:HU754 RS10450
gene id: 2745510:HU754_RS10450
uniprot id: A0A9E6TD72
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

2745510:HU754 RS29020
gene id: 2745510:HU754_RS29020
uniprot id: A0A9E6NQ51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

2745510:HU754 RS07110
gene id: 2745510:HU754_RS07110
uniprot id: A0A9E6TCK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

2745510:HU754 RS29030
gene id: 2745510:HU754_RS29030
uniprot id: A0A9E6NPN4
names: Similarity
messages: Belongs to the thioredoxin family.

2745510:HU754 RS18025
gene id: 2745510:HU754_RS18025
uniprot id: A0A9E6NKF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

2745510:HU754 RS27495
gene id: 2745510:HU754_RS27495
uniprot id: A0A9E6TB28
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2745510:HU754 RS09875
gene id: 2745510:HU754_RS09875
uniprot id: A0A9E6TDD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2745510:HU754 RS02965
gene id: 2745510:HU754_RS02965
uniprot id: A0A9E6NQE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

2745510:HU754 RS03815
gene id: 2745510:HU754_RS03815
uniprot id: A0A9E6NRD4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

2745510:HU754 RS07075
gene id: 2745510:HU754_RS07075
uniprot id: A0A9E6NRZ4
names: Similarity
messages: Belongs to the Skp family.

2745510:HU754 RS02935
gene id: 2745510:HU754_RS02935
uniprot id: A0A9E6NRL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745510:HU754 RS00155
gene id: 2745510:HU754_RS00155
uniprot id: A0A9E6NPF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

2745510:HU754 RS10485
gene id: 2745510:HU754_RS10485
uniprot id: A0A9E6NT37
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745510:HU754 RS22870
gene id: 2745510:HU754_RS22870
uniprot id: A0A9E6NMU0
names: Similarity
messages: Belongs to the YciI family.

2745510:HU754 RS02705
gene id: 2745510:HU754_RS02705
uniprot id: A0A9E6NRK0
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

2745510:HU754 RS09075
gene id: 2745510:HU754_RS09075
uniprot id: A0A9E6NV81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

2745510:HU754 RS00560
gene id: 2745510:HU754_RS00560
uniprot id: A0A9E6NQ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2745510:HU754 RS06630
gene id: 2745510:HU754_RS06630
uniprot id: A0A9E6TCH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

2745510:HU754 RS02540
gene id: 2745510:HU754_RS02540
uniprot id: A0A9E6NR27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

2745510:HU754 RS10605
gene id: 2745510:HU754_RS10605
uniprot id: A0A9E6TD30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

2745510:HU754 RS04475
gene id: 2745510:HU754_RS04475
uniprot id: A0A9E6NR45
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

2745510:HU754 RS15340
gene id: 2745510:HU754_RS15340
uniprot id: A0A9E6NJI2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

2745510:HU754 RS27165
gene id: 2745510:HU754_RS27165
uniprot id: A0A9E6TBA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2745510:HU754 RS10095
gene id: 2745510:HU754_RS10095
uniprot id: A0A9E6NT57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

2745510:HU754 RS07380
gene id: 2745510:HU754_RS07380
uniprot id: A0A9E6NT90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

2745510:HU754 RS28415
gene id: 2745510:HU754_RS28415
uniprot id: A0A9E6TBE2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

2745510:HU754 RS16615
gene id: 2745510:HU754_RS16615
uniprot id: A0A9E6T948
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

2745510:HU754 RS09235
gene id: 2745510:HU754_RS09235
uniprot id: A0A9E6NT82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2745510:HU754 RS12715
gene id: 2745510:HU754_RS12715
uniprot id: A0A9E6NU13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745510:HU754 RS03195
gene id: 2745510:HU754_RS03195
uniprot id: A0A9E6NQH5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745510:HU754 RS24615
gene id: 2745510:HU754_RS24615
uniprot id: A0A9E6NNI6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane
messages: The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains.

2745510:HU754 RS28435
gene id: 2745510:HU754_RS28435
uniprot id: A0A9E6NPU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

2745510:HU754 RS03730
gene id: 2745510:HU754_RS03730
uniprot id: A0A9E6NQP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

2745510:HU754 RS05895
gene id: 2745510:HU754_RS05895
uniprot id: A0A9E6NSN2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

2745510:HU754 RS03095
gene id: 2745510:HU754_RS03095
uniprot id: A0A9E6NQH2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

2745510:HU754 RS10540
gene id: 2745510:HU754_RS10540
uniprot id: A0A9E6TDK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

2745510:HU754 RS11470
gene id: 2745510:HU754_RS11470
uniprot id: A0A9E6TDH1
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

2745510:HU754 RS27070
gene id: 2745510:HU754_RS27070
uniprot id: A0A9E6TB59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2745510:HU754 RS26520
gene id: 2745510:HU754_RS26520
uniprot id: A0A9E6NP79
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

2745510:HU754 RS27595
gene id: 2745510:HU754_RS27595
uniprot id: A0A9E6TBC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PqqD family.
messages: Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
messages: Monomer. Interacts with PqqE.

2745510:HU754 RS00545
gene id: 2745510:HU754_RS00545
uniprot id: A0A9E6NVF6
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

2745510:HU754 RS10970
gene id: 2745510:HU754_RS10970
uniprot id: A0A9E6NU27
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745510:HU754 RS24375
gene id: 2745510:HU754_RS24375
uniprot id: A0A9E6NMR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

2745510:HU754 RS24730
gene id: 2745510:HU754_RS24730
uniprot id: A0A9E6TAN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

2745510:HU754 RS08360
gene id: 2745510:HU754_RS08360
uniprot id: A0A9E6TD54
names: Subcellular Location Annotation
messages: Cytoplasm

2745510:HU754 RS08340
gene id: 2745510:HU754_RS08340
uniprot id: A0A9E6NST2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

2745510:HU754 RS03115
gene id: 2745510:HU754_RS03115
uniprot id: A0A9E6NRC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2745510:HU754 RS05645
gene id: 2745510:HU754_RS05645
uniprot id: A0A9E6TCV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

2745510:HU754 RS26105
gene id: 2745510:HU754_RS26105
uniprot id: A0A9E6NNK1
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

2745510:HU754 RS00185
gene id: 2745510:HU754_RS00185
uniprot id: A0A9E6TBN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

2745510:HU754 RS27150
gene id: 2745510:HU754_RS27150
uniprot id: A0A9E6TB11
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2745510:HU754 RS22050
gene id: 2745510:HU754_RS22050
uniprot id: A0A9E6NV03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

2745510:HU754 RS00995
gene id: 2745510:HU754_RS00995
uniprot id: A0A9E6NQI0
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

2745510:HU754 RS11515
gene id: 2745510:HU754_RS11515
uniprot id: A0A9E6NTM3
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

2745510:HU754 RS19130
gene id: 2745510:HU754_RS19130
uniprot id: A0A9E6T9U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

2745510:HU754 RS05605
gene id: 2745510:HU754_RS05605
uniprot id: A0A9E6NRU6
names: Similarity
messages: Belongs to the UxaA family.

2745510:HU754 RS12895
gene id: 2745510:HU754_RS12895
uniprot id: A0A9E6TE11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 4-oxalocrotonate tautomerase family.
messages: Catalyzes the ketonization of 2-hydroxymuconate stereoselectively to yield 2-oxo-3-hexenedioate.
messages: Homohexamer.

2745510:HU754 RS26790
gene id: 2745510:HU754_RS26790
uniprot id: A0A9E6TB76
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

2745510:HU754 RS05460
gene id: 2745510:HU754_RS05460
uniprot id: A0A9E6NRC0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

2745510:HU754 RS27370
gene id: 2745510:HU754_RS27370
uniprot id: A0A9E6NPF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745510:HU754 RS08270
gene id: 2745510:HU754_RS08270
uniprot id: A0A9E6NT62
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

2745510:HU754 RS01125
gene id: 2745510:HU754_RS01125
uniprot id: A0A9E6TBL2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

2745510:HU754 RS10080
gene id: 2745510:HU754_RS10080
uniprot id: A0A9E6NT17
names: Similarity
messages: Belongs to the allantoicase family.

2745510:HU754 RS13310
gene id: 2745510:HU754_RS13310
uniprot id: A0A9E6NU88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745510:HU754 RS00190
gene id: 2745510:HU754_RS00190
uniprot id: A0A9E6NPF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2745510:HU754 RS02790
gene id: 2745510:HU754_RS02790
uniprot id: A0A9E6NR60
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

2745510:HU754 RS07045
gene id: 2745510:HU754_RS07045
uniprot id: A0A9E6TD25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

2745510:HU754 RS18010
gene id: 2745510:HU754_RS18010
uniprot id: A0A9E6T9D5
names: Subcellular Location Annotation
messages: Membrane

2745510:HU754 RS25420
gene id: 2745510:HU754_RS25420
uniprot id: A0A9E6TAZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

2745510:HU754 RS10600
gene id: 2745510:HU754_RS10600
uniprot id: A0A9E6TD93
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

2745510:HU754 RS03355
gene id: 2745510:HU754_RS03355
uniprot id: A0A9E6NQJ7
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

2745510:HU754 RS02025
gene id: 2745510:HU754_RS02025
uniprot id: A0A9E6TBM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

2745510:HU754 RS02800
gene id: 2745510:HU754_RS02800
uniprot id: A0A9E6NR04
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

2745510:HU754 RS10480
gene id: 2745510:HU754_RS10480
uniprot id: A0A9E6NUB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

2745510:HU754 RS29280
gene id: 2745510:HU754_RS29280
uniprot id: A0A9E6TBM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

2745510:HU754 RS05755
gene id: 2745510:HU754_RS05755
uniprot id: A0A9E6NRK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.

2745510:HU754 RS29085
gene id: 2745510:HU754_RS29085
uniprot id: A0A9E6NPF4
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

2745510:HU754 RS09920
gene id: 2745510:HU754_RS09920
uniprot id: A0A9E6NSX7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2745510:HU754 RS22965
gene id: 2745510:HU754_RS22965
uniprot id: A0A9E6NMY4
names: Subcellular Location Annotation
messages: Membrane

2745510:HU754 RS23065
gene id: 2745510:HU754_RS23065
uniprot id: A0A9E6NM46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745510:HU754 RS01200
gene id: 2745510:HU754_RS01200
uniprot id: A0A9E6TBU5
names: Subcellular Location Annotation
messages: Membrane

2745510:HU754 RS26805
gene id: 2745510:HU754_RS26805
uniprot id: A0A9E6NPQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

2745510:HU754 RS12060
gene id: 2745510:HU754_RS12060
uniprot id: A0A9E6NUF2
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

2745510:HU754 RS05840
gene id: 2745510:HU754_RS05840
uniprot id: A0A9E6NSC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

2745510:HU754 RS12490
gene id: 2745510:HU754_RS12490
uniprot id: A0A9E6TE04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the agmatine deiminase family.
messages: Homodimer.
messages: Mediates the hydrolysis of agmatine into N-carbamoylputrescine in the arginine decarboxylase (ADC) pathway of putrescine biosynthesis, a basic polyamine.

2745510:HU754 RS01025
gene id: 2745510:HU754_RS01025
uniprot id: A0A9E6NQM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

2745510:HU754 RS00980
gene id: 2745510:HU754_RS00980
uniprot id: A0A9E6TBW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2745510:HU754 RS09925
gene id: 2745510:HU754_RS09925
uniprot id: A0A9E6NTW5
names: Subcellular Location Annotation
messages: Membrane

2745510:HU754 RS28835
gene id: 2745510:HU754_RS28835
uniprot id: A0A9E6NP54
names: Function
names: Similarity
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.

2745510:HU754 RS25550
gene id: 2745510:HU754_RS25550
uniprot id: A0A9E6TAW2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

2745510:HU754 RS01085
gene id: 2745510:HU754_RS01085
uniprot id: A0A9E6NPR3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2745510:HU754 RS05470
gene id: 2745510:HU754_RS05470
uniprot id: A0A9E6TCJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745510:HU754 RS24865
gene id: 2745510:HU754_RS24865
uniprot id: A0A9E6NNL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2745510:HU754 RS25840
gene id: 2745510:HU754_RS25840
uniprot id: A0A9E6NNU9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2745510:HU754 RS21535
gene id: 2745510:HU754_RS21535
uniprot id: A0A9E6NMU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

2745510:HU754 RS20020
gene id: 2745510:HU754_RS20020
uniprot id: A0A9E6NMB0
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

2745510:HU754 RS28005
gene id: 2745510:HU754_RS28005
uniprot id: A0A9E6NPI1
names: Subcellular Location Annotation
messages: Membrane

2745510:HU754 RS23965
gene id: 2745510:HU754_RS23965
uniprot id: A0A9E6NN75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

2745510:HU754 RS27010
gene id: 2745510:HU754_RS27010
uniprot id: A0A9E6TB55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2745510:HU754 RS04230
gene id: 2745510:HU754_RS04230
uniprot id: A0A9E6NS09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

2745510:HU754 RS20150
gene id: 2745510:HU754_RS20150
uniprot id: A0A9E6T9Q5
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

2745510:HU754 RS09070
gene id: 2745510:HU754_RS09070
uniprot id: A0A9E6NSS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.