2745504:HU739 RS26250
gene id: 2745504:HU739_RS26250
uniprot id: A0A9E6NZQ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

2745504:HU739 RS10340
gene id: 2745504:HU739_RS10340
uniprot id: A0A9E6P476
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745504:HU739 RS06780
gene id: 2745504:HU739_RS06780
uniprot id: A0A9E6TIH2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

2745504:HU739 RS18000
gene id: 2745504:HU739_RS18000
uniprot id: A0A9E6TFC8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

2745504:HU739 RS18260
gene id: 2745504:HU739_RS18260
uniprot id: A0A9E6NXT1
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

2745504:HU739 RS17670
gene id: 2745504:HU739_RS17670
uniprot id: A0A9E6NX27
names: Subcellular Location Annotation
messages: Membrane

2745504:HU739 RS09810
gene id: 2745504:HU739_RS09810
uniprot id: A0A9E6P3Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

2745504:HU739 RS13690
gene id: 2745504:HU739_RS13690
uniprot id: A0A9E6NVA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

2745504:HU739 RS01510
gene id: 2745504:HU739_RS01510
uniprot id: A0A9E6P0X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

2745504:HU739 RS26570
gene id: 2745504:HU739_RS26570
uniprot id: A0A9E6P0D5
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

2745504:HU739 RS01395
gene id: 2745504:HU739_RS01395
uniprot id: A0A9E6TH21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

2745504:HU739 RS09535
gene id: 2745504:HU739_RS09535
uniprot id: A0A9E6P350
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

2745504:HU739 RS24640
gene id: 2745504:HU739_RS24640
uniprot id: A0A9E6P010
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

2745504:HU739 RS19650
gene id: 2745504:HU739_RS19650
uniprot id: A0A9E6TFB5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

2745504:HU739 RS17710
gene id: 2745504:HU739_RS17710
uniprot id: A0A9E6NXR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

2745504:HU739 RS25520
gene id: 2745504:HU739_RS25520
uniprot id: A0A9E6P003
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

2745504:HU739 RS11580
gene id: 2745504:HU739_RS11580
uniprot id: A0A9E6P4Y2
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

2745504:HU739 RS01060
gene id: 2745504:HU739_RS01060
uniprot id: A0A9E6P056
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2745504:HU739 RS26015
gene id: 2745504:HU739_RS26015
uniprot id: A0A9E6TG36
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2745504:HU739 RS13680
gene id: 2745504:HU739_RS13680
uniprot id: A0A9E6NVX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2745504:HU739 RS25975
gene id: 2745504:HU739_RS25975
uniprot id: A0A9E6P0P9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2745504:HU739 RS13700
gene id: 2745504:HU739_RS13700
uniprot id: A0A9E6TEP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

2745504:HU739 RS26080
gene id: 2745504:HU739_RS26080
uniprot id: A0A9E6TH05
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2745504:HU739 RS20645
gene id: 2745504:HU739_RS20645
uniprot id: A0A9E6NYD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745504:HU739 RS09800
gene id: 2745504:HU739_RS09800
uniprot id: A0A9E6P414
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

2745504:HU739 RS23700
gene id: 2745504:HU739_RS23700
uniprot id: A0A9E6NZQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

2745504:HU739 RS17675
gene id: 2745504:HU739_RS17675
uniprot id: A0A9E6TFK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

2745504:HU739 RS01430
gene id: 2745504:HU739_RS01430
uniprot id: A0A9E6P0D2
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

2745504:HU739 RS12690
gene id: 2745504:HU739_RS12690
uniprot id: A0A9E6P4G5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

2745504:HU739 RS21405
gene id: 2745504:HU739_RS21405
uniprot id: A0A9E6NZ03
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

2745504:HU739 RS08695
gene id: 2745504:HU739_RS08695
uniprot id: A0A9E6P384
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745504:HU739 RS11590
gene id: 2745504:HU739_RS11590
uniprot id: A0A9E6P524
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

2745504:HU739 RS11915
gene id: 2745504:HU739_RS11915
uniprot id: A0A9E6P474
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

2745504:HU739 RS26005
gene id: 2745504:HU739_RS26005
uniprot id: A0A9E6TH03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2745504:HU739 RS09080
gene id: 2745504:HU739_RS09080
uniprot id: A0A9E6P3S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ureidoglycolate lyase family.
messages: Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.
messages: Homodimer.

2745504:HU739 RS12520
gene id: 2745504:HU739_RS12520
uniprot id: A0A9E6P5G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

2745504:HU739 RS17025
gene id: 2745504:HU739_RS17025
uniprot id: A0A9E6NWA9
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

2745504:HU739 RS24140
gene id: 2745504:HU739_RS24140
uniprot id: A0A9E6TGQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2745504:HU739 RS26160
gene id: 2745504:HU739_RS26160
uniprot id: A0A9E6TGA7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

2745504:HU739 RS09540
gene id: 2745504:HU739_RS09540
uniprot id: A0A9E6P4C7
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

2745504:HU739 RS18180
gene id: 2745504:HU739_RS18180
uniprot id: A0A9E6NXS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

2745504:HU739 RS26010
gene id: 2745504:HU739_RS26010
uniprot id: A0A9E6TG99
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2745504:HU739 RS26540
gene id: 2745504:HU739_RS26540
uniprot id: A0A9E6P503
names: Function
names: Similarity
messages: Belongs to the PqqA family.
messages: Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.

2745504:HU739 RS19815
gene id: 2745504:HU739_RS19815
uniprot id: A0A9E6TFN0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

2745504:HU739 RS12515
gene id: 2745504:HU739_RS12515
uniprot id: A0A9E6P4C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

2745504:HU739 RS22095
gene id: 2745504:HU739_RS22095
uniprot id: A0A9E6NZ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745504:HU739 RS26090
gene id: 2745504:HU739_RS26090
uniprot id: A0A9E6TG40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2745504:HU739 RS23365
gene id: 2745504:HU739_RS23365
uniprot id: A0A9E6NZT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745504:HU739 RS26050
gene id: 2745504:HU739_RS26050
uniprot id: A0A9E6P0Q9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2745504:HU739 RS13305
gene id: 2745504:HU739_RS13305
uniprot id: A0A9E6TE87
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

2745504:HU739 RS15665
gene id: 2745504:HU739_RS15665
uniprot id: A0A9E6NWX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

2745504:HU739 RS23730
gene id: 2745504:HU739_RS23730
uniprot id: A0A9E6TGM7
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

2745504:HU739 RS23775
gene id: 2745504:HU739_RS23775
uniprot id: A0A9E6NYQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

2745504:HU739 RS20965
gene id: 2745504:HU739_RS20965
uniprot id: A0A9E6NYR2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

2745504:HU739 RS12405
gene id: 2745504:HU739_RS12405
uniprot id: A0A9E6TIP5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

2745504:HU739 RS21480
gene id: 2745504:HU739_RS21480
uniprot id: A0A9E6NZ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

2745504:HU739 RS06115
gene id: 2745504:HU739_RS06115
uniprot id: A0A9E6P1Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

2745504:HU739 RS25990
gene id: 2745504:HU739_RS25990
uniprot id: A0A9E6P0E7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2745504:HU739 RS01445
gene id: 2745504:HU739_RS01445
uniprot id: A0A9E6P0A7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745504:HU739 RS15660
gene id: 2745504:HU739_RS15660
uniprot id: A0A9E6NVT9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

2745504:HU739 RS24635
gene id: 2745504:HU739_RS24635
uniprot id: A0A9E6NZQ8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745504:HU739 RS14845
gene id: 2745504:HU739_RS14845
uniprot id: A0A9E6TEH6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

2745504:HU739 RS25015
gene id: 2745504:HU739_RS25015
uniprot id: A0A9E6P013
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2745504:HU739 RS16040
gene id: 2745504:HU739_RS16040
uniprot id: A0A9E6NX64
names: Similarity
messages: Belongs to the VapB family.

2745504:HU739 RS10345
gene id: 2745504:HU739_RS10345
uniprot id: A0A9E6P3P5
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

2745504:HU739 RS15930
gene id: 2745504:HU739_RS15930
uniprot id: A0A9E6TEM6
names: Similarity
messages: Belongs to the peptidase S41A family.

2745504:HU739 RS16450
gene id: 2745504:HU739_RS16450
uniprot id: A0A9E6NXB0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

2745504:HU739 RS13785
gene id: 2745504:HU739_RS13785
uniprot id: A0A9E6NVB3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

2745504:HU739 RS25755
gene id: 2745504:HU739_RS25755
uniprot id: A0A9E6NZH7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

2745504:HU739 RS11910
gene id: 2745504:HU739_RS11910
uniprot id: A0A9E6P4P3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

2745504:HU739 RS22960
gene id: 2745504:HU739_RS22960
uniprot id: A0A9E6NYJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

2745504:HU739 RS06770
gene id: 2745504:HU739_RS06770
uniprot id: A0A9E6THC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745504:HU739 RS23710
gene id: 2745504:HU739_RS23710
uniprot id: A0A9E6NZF1
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

2745504:HU739 RS12630
gene id: 2745504:HU739_RS12630
uniprot id: A0A9E6TIQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745504:HU739 RS24130
gene id: 2745504:HU739_RS24130
uniprot id: A0A9E6NYX1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

2745504:HU739 RS10620
gene id: 2745504:HU739_RS10620
uniprot id: A0A9E6P4P8
names: Similarity
messages: Belongs to the UPF0260 family.

2745504:HU739 RS09550
gene id: 2745504:HU739_RS09550
uniprot id: A0A9E6P356
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

2745504:HU739 RS18990
gene id: 2745504:HU739_RS18990
uniprot id: A0A9E6NXZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745504:HU739 RS18600
gene id: 2745504:HU739_RS18600
uniprot id: A0A9E6NXC3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2745504:HU739 RS26060
gene id: 2745504:HU739_RS26060
uniprot id: A0A9E6P073
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2745504:HU739 RS06735
gene id: 2745504:HU739_RS06735
uniprot id: A0A9E6P2B6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

2745504:HU739 RS14465
gene id: 2745504:HU739_RS14465
uniprot id: A0A9E6TER3
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

2745504:HU739 RS20355
gene id: 2745504:HU739_RS20355
uniprot id: A0A9E6TFS4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745504:HU739 RS07965
gene id: 2745504:HU739_RS07965
uniprot id: A0A9E6THK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

2745504:HU739 RS24175
gene id: 2745504:HU739_RS24175
uniprot id: A0A9E6NYZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

2745504:HU739 RS25145
gene id: 2745504:HU739_RS25145
uniprot id: A0A9E6TIN2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

2745504:HU739 RS26475
gene id: 2745504:HU739_RS26475
uniprot id: A0A9E6NZT3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2745504:HU739 RS21160
gene id: 2745504:HU739_RS21160
uniprot id: A0A9E6TFW6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2745504:HU739 RS05765
gene id: 2745504:HU739_RS05765
uniprot id: A0A9E6TI45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745504:HU739 RS17705
gene id: 2745504:HU739_RS17705
uniprot id: A0A9E6NXF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

2745504:HU739 RS13105
gene id: 2745504:HU739_RS13105
uniprot id: A0A9E6TJM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

2745504:HU739 RS01410
gene id: 2745504:HU739_RS01410
uniprot id: A0A9E6P1B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745504:HU739 RS26155
gene id: 2745504:HU739_RS26155
uniprot id: A0A9E6TH06
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2745504:HU739 RS09920
gene id: 2745504:HU739_RS09920
uniprot id: A0A9E6P4H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2745504:HU739 RS18500
gene id: 2745504:HU739_RS18500
uniprot id: A0A9E6NX08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

2745504:HU739 RS13685
gene id: 2745504:HU739_RS13685
uniprot id: A0A9E6NW14
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

2745504:HU739 RS18995
gene id: 2745504:HU739_RS18995
uniprot id: A0A9E6NX40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745504:HU739 RS26025
gene id: 2745504:HU739_RS26025
uniprot id: A0A9E6TH51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

2745504:HU739 RS26105
gene id: 2745504:HU739_RS26105
uniprot id: A0A9E6NZP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2745504:HU739 RS09280
gene id: 2745504:HU739_RS09280
uniprot id: A0A9E6THS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2745504:HU739 RS25770
gene id: 2745504:HU739_RS25770
uniprot id: A0A9E6NZG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

2745504:HU739 RS12000
gene id: 2745504:HU739_RS12000
uniprot id: A0A9E6P482
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745504:HU739 RS16455
gene id: 2745504:HU739_RS16455
uniprot id: A0A9E6NW42
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

2745504:HU739 RS14485
gene id: 2745504:HU739_RS14485
uniprot id: A0A9E6NVE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

2745504:HU739 RS09875
gene id: 2745504:HU739_RS09875
uniprot id: A0A9E6P424
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2745504:HU739 RS24435
gene id: 2745504:HU739_RS24435
uniprot id: A0A9E6NZN0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

2745504:HU739 RS08640
gene id: 2745504:HU739_RS08640
uniprot id: A0A9E6TI96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

2745504:HU739 RS26550
gene id: 2745504:HU739_RS26550
uniprot id: A0A9E6P0U1
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

2745504:HU739 RS15955
gene id: 2745504:HU739_RS15955
uniprot id: A0A9E6NWL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

2745504:HU739 RS25995
gene id: 2745504:HU739_RS25995
uniprot id: A0A9E6NZJ5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2745504:HU739 RS19330
gene id: 2745504:HU739_RS19330
uniprot id: A0A9E6TFV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

2745504:HU739 RS26150
gene id: 2745504:HU739_RS26150
uniprot id: A0A9E6P017
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

2745504:HU739 RS20150
gene id: 2745504:HU739_RS20150
uniprot id: A0A9E6NXE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
messages: Homotetramer.

2745504:HU739 RS09020
gene id: 2745504:HU739_RS09020
uniprot id: A0A9E6TIP7
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

2745504:HU739 RS15905
gene id: 2745504:HU739_RS15905
uniprot id: A0A9E6NWP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

2745504:HU739 RS26290
gene id: 2745504:HU739_RS26290
uniprot id: A0A9E6TGQ1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

2745504:HU739 RS25790
gene id: 2745504:HU739_RS25790
uniprot id: A0A9E6TG22
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

2745504:HU739 RS21115
gene id: 2745504:HU739_RS21115
uniprot id: A0A9E6NXX7
names: Similarity
messages: Belongs to the UPF0270 family.

2745504:HU739 RS13265
gene id: 2745504:HU739_RS13265
uniprot id: A0A9E6NW31
names: Similarity
messages: Belongs to the peptidase U62 family.

2745504:HU739 RS15975
gene id: 2745504:HU739_RS15975
uniprot id: A0A9E6NW40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

2745504:HU739 RS06695
gene id: 2745504:HU739_RS06695
uniprot id: A0A9E6THC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745504:HU739 RS26030
gene id: 2745504:HU739_RS26030
uniprot id: A0A9E6NZN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2745504:HU739 RS11260
gene id: 2745504:HU739_RS11260
uniprot id: A0A9E6P3U5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2745504:HU739 RS23715
gene id: 2745504:HU739_RS23715
uniprot id: A0A9E6NZQ9
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

2745504:HU739 RS24005
gene id: 2745504:HU739_RS24005
uniprot id: A0A9E6P029
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

2745504:HU739 RS09120
gene id: 2745504:HU739_RS09120
uniprot id: A0A9E6P302
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

2745504:HU739 RS24100
gene id: 2745504:HU739_RS24100
uniprot id: A0A9E6P041
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

2745504:HU739 RS22025
gene id: 2745504:HU739_RS22025
uniprot id: A0A9E6NZ43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

2745504:HU739 RS18605
gene id: 2745504:HU739_RS18605
uniprot id: A0A9E6TFR1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2745504:HU739 RS12400
gene id: 2745504:HU739_RS12400
uniprot id: A0A9E6TJA1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

2745504:HU739 RS21695
gene id: 2745504:HU739_RS21695
uniprot id: A0A9E6TGA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

2745504:HU739 RS01075
gene id: 2745504:HU739_RS01075
uniprot id: A0A9E6TGK2
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

2745504:HU739 RS26075
gene id: 2745504:HU739_RS26075
uniprot id: A0A9E6P005
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2745504:HU739 RS22725
gene id: 2745504:HU739_RS22725
uniprot id: A0A9E6NYG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

2745504:HU739 RS23680
gene id: 2745504:HU739_RS23680
uniprot id: A0A9E6NYT7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

2745504:HU739 RS09125
gene id: 2745504:HU739_RS09125
uniprot id: A0A9E6P473
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

2745504:HU739 RS12385
gene id: 2745504:HU739_RS12385
uniprot id: A0A9E6P4U2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2745504:HU739 RS25970
gene id: 2745504:HU739_RS25970
uniprot id: A0A9E6NZH2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2745504:HU739 RS18770
gene id: 2745504:HU739_RS18770
uniprot id: A0A9E6NXE3
names: Similarity
messages: Belongs to the P(II) protein family.

2745504:HU739 RS19555
gene id: 2745504:HU739_RS19555
uniprot id: A0A9E6NX95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

2745504:HU739 RS26125
gene id: 2745504:HU739_RS26125
uniprot id: A0A9E6P0R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2745504:HU739 RS25985
gene id: 2745504:HU739_RS25985
uniprot id: A0A9E6P064
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2745504:HU739 RS14750
gene id: 2745504:HU739_RS14750
uniprot id: A0A9E6NVK4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745504:HU739 RS13775
gene id: 2745504:HU739_RS13775
uniprot id: A0A9E6NVY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

2745504:HU739 RS17365
gene id: 2745504:HU739_RS17365
uniprot id: A0A9E6TFI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

2745504:HU739 RS22680
gene id: 2745504:HU739_RS22680
uniprot id: A0A9E6NYD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2745504:HU739 RS10785
gene id: 2745504:HU739_RS10785
uniprot id: A0A9E6P4R1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745504:HU739 RS23895
gene id: 2745504:HU739_RS23895
uniprot id: A0A9E6TG09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

2745504:HU739 RS25010
gene id: 2745504:HU739_RS25010
uniprot id: A0A9E6NZA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

2745504:HU739 RS01985
gene id: 2745504:HU739_RS01985
uniprot id: A0A9E6P1G5
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

2745504:HU739 RS20970
gene id: 2745504:HU739_RS20970
uniprot id: A0A9E6NXT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

2745504:HU739 RS03260
gene id: 2745504:HU739_RS03260
uniprot id: A0A9E6P0W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

2745504:HU739 RS08070
gene id: 2745504:HU739_RS08070
uniprot id: A0A9E6THK9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745504:HU739 RS17205
gene id: 2745504:HU739_RS17205
uniprot id: A0A9E6NWX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

2745504:HU739 RS07860
gene id: 2745504:HU739_RS07860
uniprot id: A0A9E6P2Q7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2745504:HU739 RS07840
gene id: 2745504:HU739_RS07840
uniprot id: A0A9E6P3W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2745504:HU739 RS23245
gene id: 2745504:HU739_RS23245
uniprot id: A0A9E6NYZ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

2745504:HU739 RS13720
gene id: 2745504:HU739_RS13720
uniprot id: A0A9E6P5M8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745504:HU739 RS22720
gene id: 2745504:HU739_RS22720
uniprot id: A0A9E6TGH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

2745504:HU739 RS13825
gene id: 2745504:HU739_RS13825
uniprot id: A0A9E6NVU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2745504:HU739 RS18250
gene id: 2745504:HU739_RS18250
uniprot id: A0A9E6NXX5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Cytoplasm

2745504:HU739 RS19015
gene id: 2745504:HU739_RS19015
uniprot id: A0A9E6TEV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

2745504:HU739 RS23720
gene id: 2745504:HU739_RS23720
uniprot id: A0A9E6NYR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

2745504:HU739 RS21720
gene id: 2745504:HU739_RS21720
uniprot id: A0A9E6NY43
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

2745504:HU739 RS25525
gene id: 2745504:HU739_RS25525
uniprot id: A0A9E6P0B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

2745504:HU739 RS15595
gene id: 2745504:HU739_RS15595
uniprot id: A0A9E6NVY9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

2745504:HU739 RS00440
gene id: 2745504:HU739_RS00440
uniprot id: A0A9E6TG83
names: Similarity
messages: Belongs to the UDPGP type 2 family.

2745504:HU739 RS19545
gene id: 2745504:HU739_RS19545
uniprot id: A0A9E6NXY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

2745504:HU739 RS07880
gene id: 2745504:HU739_RS07880
uniprot id: A0A9E6THW0
names: Subcellular Location Annotation
messages: Cytoplasm

2745504:HU739 RS15125
gene id: 2745504:HU739_RS15125
uniprot id: A0A9E6NVM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2745504:HU739 RS23755
gene id: 2745504:HU739_RS23755
uniprot id: A0A9E6TGP1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

2745504:HU739 RS16790
gene id: 2745504:HU739_RS16790
uniprot id: A0A9E6NX76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745504:HU739 RS18530
gene id: 2745504:HU739_RS18530
uniprot id: A0A9E6TF37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2745504:HU739 RS26120
gene id: 2745504:HU739_RS26120
uniprot id: A0A9E6NZJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2745504:HU739 RS18820
gene id: 2745504:HU739_RS18820
uniprot id: A0A9E6NY05
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

2745504:HU739 RS11905
gene id: 2745504:HU739_RS11905
uniprot id: A0A9E6P4A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2745504:HU739 RS17635
gene id: 2745504:HU739_RS17635
uniprot id: A0A9E6NXQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

2745504:HU739 RS21185
gene id: 2745504:HU739_RS21185
uniprot id: A0A9E6NYU6
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

2745504:HU739 RS11490
gene id: 2745504:HU739_RS11490
uniprot id: A0A9E6P521
names: Subcellular Location Annotation
messages: Cytoplasm

2745504:HU739 RS13800
gene id: 2745504:HU739_RS13800
uniprot id: A0A9E6TEB4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

2745504:HU739 RS17625
gene id: 2745504:HU739_RS17625
uniprot id: A0A9E6NXE4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2745504:HU739 RS11965
gene id: 2745504:HU739_RS11965
uniprot id: A0A9E6P571
names: Similarity
messages: Belongs to the Skp family.

2745504:HU739 RS23910
gene id: 2745504:HU739_RS23910
uniprot id: A0A9E6TGQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

2745504:HU739 RS18560
gene id: 2745504:HU739_RS18560
uniprot id: A0A9E6NY13
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

2745504:HU739 RS10610
gene id: 2745504:HU739_RS10610
uniprot id: A0A9E6P3F8
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

2745504:HU739 RS20410
gene id: 2745504:HU739_RS20410
uniprot id: A0A9E6NY11
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

2745504:HU739 RS25485
gene id: 2745504:HU739_RS25485
uniprot id: A0A9E6NZG7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

2745504:HU739 RS21385
gene id: 2745504:HU739_RS21385
uniprot id: A0A9E6TFY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

2745504:HU739 RS13300
gene id: 2745504:HU739_RS13300
uniprot id: A0A9E6TEM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

2745504:HU739 RS01450
gene id: 2745504:HU739_RS01450
uniprot id: A0A9E6P0R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745504:HU739 RS01065
gene id: 2745504:HU739_RS01065
uniprot id: A0A9E6P0L1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2745504:HU739 RS07855
gene id: 2745504:HU739_RS07855
uniprot id: A0A9E6P3E8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2745504:HU739 RS01455
gene id: 2745504:HU739_RS01455
uniprot id: A0A9E6THD1
names: Cofactor
messages: Can also use Mn(2+) ion.

2745504:HU739 RS26085
gene id: 2745504:HU739_RS26085
uniprot id: A0A9E6TGA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2745504:HU739 RS25715
gene id: 2745504:HU739_RS25715
uniprot id: A0A9E6TG18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2745504:HU739 RS00225
gene id: 2745504:HU739_RS00225
uniprot id: A0A9E6TH96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

2745504:HU739 RS18225
gene id: 2745504:HU739_RS18225
uniprot id: A0A9E6TER1
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

2745504:HU739 RS01515
gene id: 2745504:HU739_RS01515
uniprot id: A0A9E6P153
names: Similarity
messages: Belongs to the ClpA/ClpB family.

2745504:HU739 RS17080
gene id: 2745504:HU739_RS17080
uniprot id: A0A9E6TF53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

2745504:HU739 RS26175
gene id: 2745504:HU739_RS26175
uniprot id: A0A9E6TGQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2745504:HU739 RS10725
gene id: 2745504:HU739_RS10725
uniprot id: A0A9E6P3U8
names: Similarity
messages: Belongs to the SAICAR synthetase family.

2745504:HU739 RS01340
gene id: 2745504:HU739_RS01340
uniprot id: A0A9E6P1I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745504:HU739 RS22645
gene id: 2745504:HU739_RS22645
uniprot id: A0A9E6NZH5
names: Subcellular Location Annotation
messages: Cytoplasm

2745504:HU739 RS24000
gene id: 2745504:HU739_RS24000
uniprot id: A0A9E6NZN7
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

2745504:HU739 RS26055
gene id: 2745504:HU739_RS26055
uniprot id: A0A9E6NZM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2745504:HU739 RS20665
gene id: 2745504:HU739_RS20665
uniprot id: A0A9E6TG42
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745504:HU739 RS26095
gene id: 2745504:HU739_RS26095
uniprot id: A0A9E6TGP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

2745504:HU739 RS19920
gene id: 2745504:HU739_RS19920
uniprot id: A0A9E6NXB2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

2745504:HU739 RS14855
gene id: 2745504:HU739_RS14855
uniprot id: A0A9E6TEV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

2745504:HU739 RS26140
gene id: 2745504:HU739_RS26140
uniprot id: A0A9E6P0G3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2745504:HU739 RS08940
gene id: 2745504:HU739_RS08940
uniprot id: A0A9E6P3B4
names: Subcellular Location Annotation
messages: Membrane

2745504:HU739 RS26065
gene id: 2745504:HU739_RS26065
uniprot id: A0A9E6P0F3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2745504:HU739 RS15830
gene id: 2745504:HU739_RS15830
uniprot id: A0A9E6NWN9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745504:HU739 RS10110
gene id: 2745504:HU739_RS10110
uniprot id: A0A9E6P3U2
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

2745504:HU739 RS21885
gene id: 2745504:HU739_RS21885
uniprot id: A0A9E6NY59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

2745504:HU739 RS19660
gene id: 2745504:HU739_RS19660
uniprot id: A0A9E6TFM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

2745504:HU739 RS26165
gene id: 2745504:HU739_RS26165
uniprot id: A0A9E6TG43
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745504:HU739 RS16330
gene id: 2745504:HU739_RS16330
uniprot id: A0A9E6NW51
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

2745504:HU739 RS19725
gene id: 2745504:HU739_RS19725
uniprot id: A0A9E6TFC0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MdcC family.
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm
messages: Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.

2745504:HU739 RS19350
gene id: 2745504:HU739_RS19350
uniprot id: A0A9E6TFJ7
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

2745504:HU739 RS09690
gene id: 2745504:HU739_RS09690
uniprot id: A0A9E6P368
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

2745504:HU739 RS24995
gene id: 2745504:HU739_RS24995
uniprot id: A0A9E6TGH9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

2745504:HU739 RS13290
gene id: 2745504:HU739_RS13290
uniprot id: A0A9E6NVK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

2745504:HU739 RS13770
gene id: 2745504:HU739_RS13770
uniprot id: A0A9E6NVA9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

2745504:HU739 RS22745
gene id: 2745504:HU739_RS22745
uniprot id: A0A9E6NZE8
names: Similarity
messages: Belongs to the Dps family.

2745504:HU739 RS26040
gene id: 2745504:HU739_RS26040
uniprot id: A0A9E6P0N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

2745504:HU739 RS23095
gene id: 2745504:HU739_RS23095
uniprot id: A0A9E6TGI6
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

2745504:HU739 RS24545
gene id: 2745504:HU739_RS24545
uniprot id: A0A9E6NZE9
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

2745504:HU739 RS06955
gene id: 2745504:HU739_RS06955
uniprot id: A0A9E6P3L1
names: Similarity
messages: Belongs to the glutamine synthetase family.

2745504:HU739 RS17690
gene id: 2745504:HU739_RS17690
uniprot id: A0A9E6TFA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

2745504:HU739 RS25570
gene id: 2745504:HU739_RS25570
uniprot id: A0A9E6TH09
names: Subcellular Location Annotation
messages: Membrane

2745504:HU739 RS18525
gene id: 2745504:HU739_RS18525
uniprot id: A0A9E6TFQ6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

2745504:HU739 RS07170
gene id: 2745504:HU739_RS07170
uniprot id: A0A9E6P2B5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

2745504:HU739 RS26000
gene id: 2745504:HU739_RS26000
uniprot id: A0A9E6NZZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2745504:HU739 RS15735
gene id: 2745504:HU739_RS15735
uniprot id: A0A9E6NVU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

2745504:HU739 RS25650
gene id: 2745504:HU739_RS25650
uniprot id: A0A9E6NZI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

2745504:HU739 RS11485
gene id: 2745504:HU739_RS11485
uniprot id: A0A9E6P3R4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745504:HU739 RS17680
gene id: 2745504:HU739_RS17680
uniprot id: A0A9E6TEY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2745504:HU739 RS21470
gene id: 2745504:HU739_RS21470
uniprot id: A0A9E6NY10
names: Similarity
messages: Belongs to the UPF0434 family.

2745504:HU739 RS08730
gene id: 2745504:HU739_RS08730
uniprot id: A0A9E6P426
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

2745504:HU739 RS16685
gene id: 2745504:HU739_RS16685
uniprot id: A0A9E6NXD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

2745504:HU739 RS19490
gene id: 2745504:HU739_RS19490
uniprot id: A0A9E6TFW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

2745504:HU739 RS14435
gene id: 2745504:HU739_RS14435
uniprot id: A0A9E6NVG5
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

2745504:HU739 RS26070
gene id: 2745504:HU739_RS26070
uniprot id: A0A9E6NZK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2745504:HU739 RS11955
gene id: 2745504:HU739_RS11955
uniprot id: A0A9E6TJG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

2745504:HU739 RS13260
gene id: 2745504:HU739_RS13260
uniprot id: A0A9E6NUX8
names: Similarity
messages: Belongs to the UPF0307 family.

2745504:HU739 RS20985
gene id: 2745504:HU739_RS20985
uniprot id: A0A9E6TFK0
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

2745504:HU739 RS19820
gene id: 2745504:HU739_RS19820
uniprot id: A0A9E6NXF3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

2745504:HU739 RS01435
gene id: 2745504:HU739_RS01435
uniprot id: A0A9E6P0W8
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

2745504:HU739 RS17685
gene id: 2745504:HU739_RS17685
uniprot id: A0A9E6TEL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

2745504:HU739 RS19010
gene id: 2745504:HU739_RS19010
uniprot id: A0A9E6TF66
names: Similarity
messages: Belongs to the thioredoxin family.

2745504:HU739 RS08535
gene id: 2745504:HU739_RS08535
uniprot id: A0A9E6P363
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

2745504:HU739 RS24890
gene id: 2745504:HU739_RS24890
uniprot id: A0A9E6P038
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

2745504:HU739 RS26020
gene id: 2745504:HU739_RS26020
uniprot id: A0A9E6TGP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

2745504:HU739 RS26340
gene id: 2745504:HU739_RS26340
uniprot id: A0A9E6NZM7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

2745504:HU739 RS03480
gene id: 2745504:HU739_RS03480
uniprot id: A0A9E6P1V8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

2745504:HU739 RS26110
gene id: 2745504:HU739_RS26110
uniprot id: A0A9E6TGQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2745504:HU739 RS18170
gene id: 2745504:HU739_RS18170
uniprot id: A0A9E6NXW5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

2745504:HU739 RS19580
gene id: 2745504:HU739_RS19580
uniprot id: A0A9E6TFM4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745504:HU739 RS25020
gene id: 2745504:HU739_RS25020
uniprot id: A0A9E6P0C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2745504:HU739 RS18580
gene id: 2745504:HU739_RS18580
uniprot id: A0A9E6NXM2
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

2745504:HU739 RS24015
gene id: 2745504:HU739_RS24015
uniprot id: A0A9E6NZU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2745504:HU739 RS16055
gene id: 2745504:HU739_RS16055
uniprot id: A0A9E6NW50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745504:HU739 RS09400
gene id: 2745504:HU739_RS09400
uniprot id: A0A9E6P339
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

2745504:HU739 RS20185
gene id: 2745504:HU739_RS20185
uniprot id: A0A9E6TG20
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

2745504:HU739 RS22700
gene id: 2745504:HU739_RS22700
uniprot id: A0A9E6TGG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2745504:HU739 RS14600
gene id: 2745504:HU739_RS14600
uniprot id: A0A9E6NW12
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

2745504:HU739 RS17610
gene id: 2745504:HU739_RS17610
uniprot id: A0A9E6TFA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

2745504:HU739 RS20955
gene id: 2745504:HU739_RS20955
uniprot id: A0A9E6NXV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2745504:HU739 RS23170
gene id: 2745504:HU739_RS23170
uniprot id: A0A9E6NYY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2745504:HU739 RS25660
gene id: 2745504:HU739_RS25660
uniprot id: A0A9E6P0I7
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

2745504:HU739 RS08515
gene id: 2745504:HU739_RS08515
uniprot id: A0A9E6P2Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

2745504:HU739 RS21400
gene id: 2745504:HU739_RS21400
uniprot id: A0A9E6NYT1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2745504:HU739 RS17700
gene id: 2745504:HU739_RS17700
uniprot id: A0A9E6NWC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

2745504:HU739 RS01405
gene id: 2745504:HU739_RS01405
uniprot id: A0A9E6P0B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745504:HU739 RS21870
gene id: 2745504:HU739_RS21870
uniprot id: A0A9E6TFC2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

2745504:HU739 RS09555
gene id: 2745504:HU739_RS09555
uniprot id: A0A9E6P4H4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

2745504:HU739 RS25960
gene id: 2745504:HU739_RS25960
uniprot id: A0A9E6P0L3
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

2745504:HU739 RS25640
gene id: 2745504:HU739_RS25640
uniprot id: A0A9E6TGL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

2745504:HU739 RS03035
gene id: 2745504:HU739_RS03035
uniprot id: A0A9E6THK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

2745504:HU739 RS20015
gene id: 2745504:HU739_RS20015
uniprot id: A0A9E6NYD7
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

2745504:HU739 RS26100
gene id: 2745504:HU739_RS26100
uniprot id: A0A9E6TH54
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2745504:HU739 RS13355
gene id: 2745504:HU739_RS13355
uniprot id: A0A9E6NV56
names: Similarity
messages: Belongs to the DapA family.

2745504:HU739 RS18520
gene id: 2745504:HU739_RS18520
uniprot id: A0A9E6NXB4
names: Similarity
messages: Belongs to the RutC family.

2745504:HU739 RS24135
gene id: 2745504:HU739_RS24135
uniprot id: A0A9E6NZA2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2745504:HU739 RS22030
gene id: 2745504:HU739_RS22030
uniprot id: A0A9E6NYA3
names: Similarity
messages: Belongs to the aspartokinase family.

2745504:HU739 RS01335
gene id: 2745504:HU739_RS01335
uniprot id: A0A9E6P070
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745504:HU739 RS01420
gene id: 2745504:HU739_RS01420
uniprot id: A0A9E6P081
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

2745504:HU739 RS01520
gene id: 2745504:HU739_RS01520
uniprot id: A0A9E6P0C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2745504:HU739 RS11950
gene id: 2745504:HU739_RS11950
uniprot id: A0A9E6TIV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

2745504:HU739 RS10745
gene id: 2745504:HU739_RS10745
uniprot id: A0A9E6P422
names: Subcellular Location Annotation
messages: Cytoplasm

2745504:HU739 RS26145
gene id: 2745504:HU739_RS26145
uniprot id: A0A9E6NZL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2745504:HU739 RS17575
gene id: 2745504:HU739_RS17575
uniprot id: A0A9E6NXA7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2745504:HU739 RS18155
gene id: 2745504:HU739_RS18155
uniprot id: A0A9E6TFB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2745504:HU739 RS14405
gene id: 2745504:HU739_RS14405
uniprot id: A0A9E6NWM5
names: Similarity
messages: Belongs to the SUI1 family.

2745504:HU739 RS25980
gene id: 2745504:HU739_RS25980
uniprot id: A0A9E6NZL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.