2745503:HU724 RS04710
gene id: 2745503:HU724_RS04710
uniprot id: A0A9E6PBV4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

2745503:HU724 RS09195
gene id: 2745503:HU724_RS09195
uniprot id: A0A9E6PDM3
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

2745503:HU724 RS18710
gene id: 2745503:HU724_RS18710
uniprot id: A0A9E6P727
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745503:HU724 RS00095
gene id: 2745503:HU724_RS00095
uniprot id: A0A9E6TL19
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2745503:HU724 RS24780
gene id: 2745503:HU724_RS24780
uniprot id: A0A9E6P8S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

2745503:HU724 RS05095
gene id: 2745503:HU724_RS05095
uniprot id: A0A9E6PCG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

2745503:HU724 RS06915
gene id: 2745503:HU724_RS06915
uniprot id: A0A9E6PC27
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS23255
gene id: 2745503:HU724_RS23255
uniprot id: A0A9E6TKW7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS21285
gene id: 2745503:HU724_RS21285
uniprot id: A0A9E6P892
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

2745503:HU724 RS00995
gene id: 2745503:HU724_RS00995
uniprot id: A0A9E6TNF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

2745503:HU724 RS09635
gene id: 2745503:HU724_RS09635
uniprot id: A0A9E6TP73
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

2745503:HU724 RS04020
gene id: 2745503:HU724_RS04020
uniprot id: A0A9E6TN60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

2745503:HU724 RS15135
gene id: 2745503:HU724_RS15135
uniprot id: A0A9E6TK29
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

2745503:HU724 RS00585
gene id: 2745503:HU724_RS00585
uniprot id: A0A9E6TMJ5
names: Similarity
messages: Belongs to the asparaginase 1 family.

2745503:HU724 RS20115
gene id: 2745503:HU724_RS20115
uniprot id: A0A9E6P8C1
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

2745503:HU724 RS25390
gene id: 2745503:HU724_RS25390
uniprot id: A0A9E6TLM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2745503:HU724 RS26960
gene id: 2745503:HU724_RS26960
uniprot id: A0A9E6P9I9
names: Similarity
messages: Belongs to the glutamine synthetase family.

2745503:HU724 RS09295
gene id: 2745503:HU724_RS09295
uniprot id: A0A9E6TMN1
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

2745503:HU724 RS07525
gene id: 2745503:HU724_RS07525
uniprot id: A0A9E6PCC7
names: Function
messages: Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions.

2745503:HU724 RS02620
gene id: 2745503:HU724_RS02620
uniprot id: A0A9E6PBJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS07495
gene id: 2745503:HU724_RS07495
uniprot id: A0A9E6TMB9
names: Function
names: Similarity
messages: An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
messages: Belongs to the SdhE FAD assembly factor family.

2745503:HU724 RS05320
gene id: 2745503:HU724_RS05320
uniprot id: A0A9E6TNE0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

2745503:HU724 RS20375
gene id: 2745503:HU724_RS20375
uniprot id: A0A9E6P7J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

2745503:HU724 RS01770
gene id: 2745503:HU724_RS01770
uniprot id: A0A9E6PB96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

2745503:HU724 RS23980
gene id: 2745503:HU724_RS23980
uniprot id: A0A9E6P9U4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2745503:HU724 RS23670
gene id: 2745503:HU724_RS23670
uniprot id: A0A9E6P9E0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

2745503:HU724 RS21885
gene id: 2745503:HU724_RS21885
uniprot id: A0A9E6P8V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

2745503:HU724 RS04655
gene id: 2745503:HU724_RS04655
uniprot id: A0A9E6PBV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

2745503:HU724 RS06680
gene id: 2745503:HU724_RS06680
uniprot id: A0A9E6TN61
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

2745503:HU724 RS00055
gene id: 2745503:HU724_RS00055
uniprot id: A0A9E6PAR6
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

2745503:HU724 RS20530
gene id: 2745503:HU724_RS20530
uniprot id: A0A9E6P7L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

2745503:HU724 RS15335
gene id: 2745503:HU724_RS15335
uniprot id: A0A9E6P5K1
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS21170
gene id: 2745503:HU724_RS21170
uniprot id: A0A9E6P8M0
names: Similarity
messages: Belongs to the WrbA family.

2745503:HU724 RS24920
gene id: 2745503:HU724_RS24920
uniprot id: A0A9E6P8V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

2745503:HU724 RS08350
gene id: 2745503:HU724_RS08350
uniprot id: A0A9E6TMH6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

2745503:HU724 RS24475
gene id: 2745503:HU724_RS24475
uniprot id: A0A9E6TLG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS02880
gene id: 2745503:HU724_RS02880
uniprot id: A0A9E6PBA1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

2745503:HU724 RS05075
gene id: 2745503:HU724_RS05075
uniprot id: A0A9E6TMS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

2745503:HU724 RS22605
gene id: 2745503:HU724_RS22605
uniprot id: A0A9E6P8C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

2745503:HU724 RS01320
gene id: 2745503:HU724_RS01320
uniprot id: A0A9E6PAF6
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

2745503:HU724 RS25135
gene id: 2745503:HU724_RS25135
uniprot id: A0A9E6P9Y1
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS20585
gene id: 2745503:HU724_RS20585
uniprot id: A0A9E6P7N4
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

2745503:HU724 RS04715
gene id: 2745503:HU724_RS04715
uniprot id: A0A9E6PBD1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

2745503:HU724 RS26800
gene id: 2745503:HU724_RS26800
uniprot id: A0A9E6PAC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

2745503:HU724 RS08985
gene id: 2745503:HU724_RS08985
uniprot id: A0A9E6PDI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

2745503:HU724 RS09240
gene id: 2745503:HU724_RS09240
uniprot id: A0A9E6PE37
names: Similarity
messages: Belongs to the allantoicase family.

2745503:HU724 RS09055
gene id: 2745503:HU724_RS09055
uniprot id: A0A9E6TNI3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2745503:HU724 RS22610
gene id: 2745503:HU724_RS22610
uniprot id: A0A9E6TL67
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

2745503:HU724 RS16570
gene id: 2745503:HU724_RS16570
uniprot id: A0A9E6P625
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2745503:HU724 RS14615
gene id: 2745503:HU724_RS14615
uniprot id: A0A9E6P5B0
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

2745503:HU724 RS22585
gene id: 2745503:HU724_RS22585
uniprot id: A0A9E6P8F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

2745503:HU724 RS18440
gene id: 2745503:HU724_RS18440
uniprot id: A0A9E6P6Y3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

2745503:HU724 RS04330
gene id: 2745503:HU724_RS04330
uniprot id: A0A9E6PC68
names: Similarity
messages: Belongs to the IMPACT family.

2745503:HU724 RS02850
gene id: 2745503:HU724_RS02850
uniprot id: A0A9E6PBT7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

2745503:HU724 RS25760
gene id: 2745503:HU724_RS25760
uniprot id: A0A9E6TKQ2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

2745503:HU724 RS22975
gene id: 2745503:HU724_RS22975
uniprot id: A0A9E6P8K3
names: Similarity
messages: Belongs to the HesB/IscA family.

2745503:HU724 RS14250
gene id: 2745503:HU724_RS14250
uniprot id: A0A9E6P580
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

2745503:HU724 RS07065
gene id: 2745503:HU724_RS07065
uniprot id: A0A9E6PC49
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS05135
gene id: 2745503:HU724_RS05135
uniprot id: A0A9E6PD41
names: Similarity
messages: Belongs to the UPF0307 family.

2745503:HU724 RS24350
gene id: 2745503:HU724_RS24350
uniprot id: A0A9E6P9L6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

2745503:HU724 RS00385
gene id: 2745503:HU724_RS00385
uniprot id: A0A9E6PA50
names: Similarity
messages: Belongs to the ClpA/ClpB family.

2745503:HU724 RS11605
gene id: 2745503:HU724_RS11605
uniprot id: A0A9E6PEG6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2745503:HU724 RS25380
gene id: 2745503:HU724_RS25380
uniprot id: A0A9E6P913
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2745503:HU724 RS22370
gene id: 2745503:HU724_RS22370
uniprot id: A0A9E6P7X0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

2745503:HU724 RS09790
gene id: 2745503:HU724_RS09790
uniprot id: A0A9E6TP79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

2745503:HU724 RS08430
gene id: 2745503:HU724_RS08430
uniprot id: A0A9E6TN22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

2745503:HU724 RS00225
gene id: 2745503:HU724_RS00225
uniprot id: A0A9E6PB66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

2745503:HU724 RS26335
gene id: 2745503:HU724_RS26335
uniprot id: A0A9E6PA63
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

2745503:HU724 RS20810
gene id: 2745503:HU724_RS20810
uniprot id: A0A9E6P7J9
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

2745503:HU724 RS00935
gene id: 2745503:HU724_RS00935
uniprot id: A0A9E6PAB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

2745503:HU724 RS21695
gene id: 2745503:HU724_RS21695
uniprot id: A0A9E6P8E0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

2745503:HU724 RS22635
gene id: 2745503:HU724_RS22635
uniprot id: A0A9E6P8P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS24970
gene id: 2745503:HU724_RS24970
uniprot id: A0A9E6P9U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2745503:HU724 RS05755
gene id: 2745503:HU724_RS05755
uniprot id: A0A9E6TMX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS09460
gene id: 2745503:HU724_RS09460
uniprot id: A0A9E6TNM8
names: Similarity
messages: Belongs to the peptidase S24 family.

2745503:HU724 RS05290
gene id: 2745503:HU724_RS05290
uniprot id: A0A9E6PBW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

2745503:HU724 RS00910
gene id: 2745503:HU724_RS00910
uniprot id: A0A9E6PA18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

2745503:HU724 RS21935
gene id: 2745503:HU724_RS21935
uniprot id: A0A9E6P8T2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

2745503:HU724 RS18055
gene id: 2745503:HU724_RS18055
uniprot id: A0A9E6P6U6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745503:HU724 RS23320
gene id: 2745503:HU724_RS23320
uniprot id: A0A9E6P9L1
names: Similarity
messages: Belongs to the UPF0102 family.

2745503:HU724 RS14870
gene id: 2745503:HU724_RS14870
uniprot id: A0A9E6P5G3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745503:HU724 RS19380
gene id: 2745503:HU724_RS19380
uniprot id: A0A9E6P7V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

2745503:HU724 RS22000
gene id: 2745503:HU724_RS22000
uniprot id: A0A9E6TK20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

2745503:HU724 RS18480
gene id: 2745503:HU724_RS18480
uniprot id: A0A9E6P704
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS08080
gene id: 2745503:HU724_RS08080
uniprot id: A0A9E6PCH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

2745503:HU724 RS17590
gene id: 2745503:HU724_RS17590
uniprot id: A0A9E6P6C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

2745503:HU724 RS12075
gene id: 2745503:HU724_RS12075
uniprot id: A0A9E6PDY4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

2745503:HU724 RS06020
gene id: 2745503:HU724_RS06020
uniprot id: A0A9E6PCR5
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

2745503:HU724 RS24785
gene id: 2745503:HU724_RS24785
uniprot id: A0A9E6P932
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

2745503:HU724 RS21025
gene id: 2745503:HU724_RS21025
uniprot id: A0A9E6TJV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2745503:HU724 RS21905
gene id: 2745503:HU724_RS21905
uniprot id: A0A9E6TKN9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2745503:HU724 RS25400
gene id: 2745503:HU724_RS25400
uniprot id: A0A9E6TKN8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2745503:HU724 RS02690
gene id: 2745503:HU724_RS02690
uniprot id: A0A9E6PBH7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS05990
gene id: 2745503:HU724_RS05990
uniprot id: A0A9E6TMM7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

2745503:HU724 RS25340
gene id: 2745503:HU724_RS25340
uniprot id: A0A9E6P9W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

2745503:HU724 RS22270
gene id: 2745503:HU724_RS22270
uniprot id: A0A9E6P939
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS03475
gene id: 2745503:HU724_RS03475
uniprot id: A0A9E6PBR7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

2745503:HU724 RS04995
gene id: 2745503:HU724_RS04995
uniprot id: A0A9E6TMS2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

2745503:HU724 RS05485
gene id: 2745503:HU724_RS05485
uniprot id: A0A9E6PCG9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS08635
gene id: 2745503:HU724_RS08635
uniprot id: A0A9E6PDD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

2745503:HU724 RS03710
gene id: 2745503:HU724_RS03710
uniprot id: A0A9E6PBY7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS23975
gene id: 2745503:HU724_RS23975
uniprot id: A0A9E6P8I0
names: Similarity
messages: Belongs to the SfsA family.

2745503:HU724 RS06000
gene id: 2745503:HU724_RS06000
uniprot id: A0A9E6PCY3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2745503:HU724 RS05215
gene id: 2745503:HU724_RS05215
uniprot id: A0A9E6PBV8
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

2745503:HU724 RS07785
gene id: 2745503:HU724_RS07785
uniprot id: A0A9E6PCV6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

2745503:HU724 RS03315
gene id: 2745503:HU724_RS03315
uniprot id: A0A9E6PBT1
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS25060
gene id: 2745503:HU724_RS25060
uniprot id: A0A9E6P9W7
names: Similarity
messages: Belongs to the thioredoxin family.

2745503:HU724 RS05705
gene id: 2745503:HU724_RS05705
uniprot id: A0A9E6PCV0
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

2745503:HU724 RS02410
gene id: 2745503:HU724_RS02410
uniprot id: A0A9E6TLC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS18010
gene id: 2745503:HU724_RS18010
uniprot id: A0A9E6TJY6
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

2745503:HU724 RS22135
gene id: 2745503:HU724_RS22135
uniprot id: A0A9E6P7T7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

2745503:HU724 RS10725
gene id: 2745503:HU724_RS10725
uniprot id: A0A9E6PE83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

2745503:HU724 RS19445
gene id: 2745503:HU724_RS19445
uniprot id: A0A9E6TKY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

2745503:HU724 RS20765
gene id: 2745503:HU724_RS20765
uniprot id: A0A9E6TKW0
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

2745503:HU724 RS06015
gene id: 2745503:HU724_RS06015
uniprot id: A0A9E6PBU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

2745503:HU724 RS19860
gene id: 2745503:HU724_RS19860
uniprot id: A0A9E6TL07
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
messages: Binds 1 Mg(2+) ion per subunit. Ca(2+) may be able to substitute.
messages: Cytoplasm
messages: Probably phosphorylates lipids; the in vivo substrate is unknown.

2745503:HU724 RS11565
gene id: 2745503:HU724_RS11565
uniprot id: A0A9E6TNY8
names: Similarity
messages: Belongs to the SCO1/2 family.

2745503:HU724 RS02670
gene id: 2745503:HU724_RS02670
uniprot id: A0A9E6TMX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

2745503:HU724 RS07890
gene id: 2745503:HU724_RS07890
uniprot id: A0A9E6TMZ0
names: Similarity
messages: Belongs to the DEAD box helicase family.

2745503:HU724 RS10210
gene id: 2745503:HU724_RS10210
uniprot id: A0A9E6PDW4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS22245
gene id: 2745503:HU724_RS22245
uniprot id: A0A9E6TLF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

2745503:HU724 RS18245
gene id: 2745503:HU724_RS18245
uniprot id: A0A9E6TK60
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

2745503:HU724 RS17985
gene id: 2745503:HU724_RS17985
uniprot id: A0A9E6P6D9
names: Similarity
messages: Belongs to the ClpA/ClpB family.

2745503:HU724 RS17980
gene id: 2745503:HU724_RS17980
uniprot id: A0A9E6P6T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2745503:HU724 RS07015
gene id: 2745503:HU724_RS07015
uniprot id: A0A9E6TN53
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2745503:HU724 RS26140
gene id: 2745503:HU724_RS26140
uniprot id: A0A9E6TLQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745503:HU724 RS18125
gene id: 2745503:HU724_RS18125
uniprot id: A0A9E6P7N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745503:HU724 RS05880
gene id: 2745503:HU724_RS05880
uniprot id: A0A9E6PBR0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

2745503:HU724 RS09685
gene id: 2745503:HU724_RS09685
uniprot id: A0A9E6PDQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

2745503:HU724 RS25860
gene id: 2745503:HU724_RS25860
uniprot id: A0A9E6PA24
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

2745503:HU724 RS05040
gene id: 2745503:HU724_RS05040
uniprot id: A0A9E6PBZ2
names: Similarity
messages: Belongs to the DapA family.

2745503:HU724 RS27200
gene id: 2745503:HU724_RS27200
uniprot id: A0A9E6PAG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS01020
gene id: 2745503:HU724_RS01020
uniprot id: A0A9E6PAM5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

2745503:HU724 RS04345
gene id: 2745503:HU724_RS04345
uniprot id: A0A9E6PBC6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS08375
gene id: 2745503:HU724_RS08375
uniprot id: A0A9E6PD85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS04750
gene id: 2745503:HU724_RS04750
uniprot id: A0A9E6TLT5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS11420
gene id: 2745503:HU724_RS11420
uniprot id: A0A9E6TN14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745503:HU724 RS00960
gene id: 2745503:HU724_RS00960
uniprot id: A0A9E6TLR2
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

2745503:HU724 RS21585
gene id: 2745503:HU724_RS21585
uniprot id: A0A9E6P7M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

2745503:HU724 RS18005
gene id: 2745503:HU724_RS18005
uniprot id: A0A9E6TKC0
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

2745503:HU724 RS07515
gene id: 2745503:HU724_RS07515
uniprot id: A0A9E6PDH2
names: Similarity
messages: Belongs to the RseA family.

2745503:HU724 RS09200
gene id: 2745503:HU724_RS09200
uniprot id: A0A9E6PDJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

2745503:HU724 RS14375
gene id: 2745503:HU724_RS14375
uniprot id: A0A9E6P633
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS05855
gene id: 2745503:HU724_RS05855
uniprot id: A0A9E6PCX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

2745503:HU724 RS08255
gene id: 2745503:HU724_RS08255
uniprot id: A0A9E6PDB6
names: Function
names: Similarity
messages: Belongs to the rhamnosyl O-methyltransferase family.
messages: Catalyzes the O-methylation of the hydroxyl group located on C-2 of the first rhamnosyl residue linked to the phenolic group of glycosylated phenolphthiocerol dimycocerosates (PGL) and p-hydroxybenzoic acid derivatives (p-HBAD).

2745503:HU724 RS00575
gene id: 2745503:HU724_RS00575
uniprot id: A0A9E6TL49
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

2745503:HU724 RS18095
gene id: 2745503:HU724_RS18095
uniprot id: A0A9E6TK50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745503:HU724 RS04725
gene id: 2745503:HU724_RS04725
uniprot id: A0A9E6PBP7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS23360
gene id: 2745503:HU724_RS23360
uniprot id: A0A9E6P8Z0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2745503:HU724 RS23420
gene id: 2745503:HU724_RS23420
uniprot id: A0A9E6TKZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS27405
gene id: 2745503:HU724_RS27405
uniprot id: A0A9E6TL12
names: Similarity
messages: Belongs to the UPF0047 family.

2745503:HU724 RS25205
gene id: 2745503:HU724_RS25205
uniprot id: A0A9E6P916
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

2745503:HU724 RS21925
gene id: 2745503:HU724_RS21925
uniprot id: A0A9E6P8F3
names: Subcellular Location Annotation
messages: Cytoplasm

2745503:HU724 RS25560
gene id: 2745503:HU724_RS25560
uniprot id: A0A9E6PA33
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS09535
gene id: 2745503:HU724_RS09535
uniprot id: A0A9E6TNN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

2745503:HU724 RS02650
gene id: 2745503:HU724_RS02650
uniprot id: A0A9E6TME6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS26640
gene id: 2745503:HU724_RS26640
uniprot id: A0A9E6PAF9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

2745503:HU724 RS26950
gene id: 2745503:HU724_RS26950
uniprot id: A0A9E6PAJ4
names: Similarity
messages: Belongs to the glutamine synthetase family.

2745503:HU724 RS20525
gene id: 2745503:HU724_RS20525
uniprot id: A0A9E6P7B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

2745503:HU724 RS01340
gene id: 2745503:HU724_RS01340
uniprot id: A0A9E6TL81
names: Similarity
messages: Belongs to the SCO1/2 family.

2745503:HU724 RS08950
gene id: 2745503:HU724_RS08950
uniprot id: A0A9E6TNH8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

2745503:HU724 RS12025
gene id: 2745503:HU724_RS12025
uniprot id: A0A9E6PF24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

2745503:HU724 RS25370
gene id: 2745503:HU724_RS25370
uniprot id: A0A9E6P914
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2745503:HU724 RS09610
gene id: 2745503:HU724_RS09610
uniprot id: A0A9E6PDN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

2745503:HU724 RS21490
gene id: 2745503:HU724_RS21490
uniprot id: A0A9E6P819
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

2745503:HU724 RS22500
gene id: 2745503:HU724_RS22500
uniprot id: A0A9E6P846
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

2745503:HU724 RS26820
gene id: 2745503:HU724_RS26820
uniprot id: A0A9E6P9G1
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

2745503:HU724 RS05105
gene id: 2745503:HU724_RS05105
uniprot id: A0A9E6PCJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

2745503:HU724 RS11255
gene id: 2745503:HU724_RS11255
uniprot id: A0A9E6PES7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily.
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate.
messages: Homotetramer; dimer of dimers.

2745503:HU724 RS22885
gene id: 2745503:HU724_RS22885
uniprot id: A0A9E6P952
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2745503:HU724 RS05045
gene id: 2745503:HU724_RS05045
uniprot id: A0A9E6PBI1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2745503:HU724 RS21835
gene id: 2745503:HU724_RS21835
uniprot id: A0A9E6TK08
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745503:HU724 RS20780
gene id: 2745503:HU724_RS20780
uniprot id: A0A9E6TKL6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

2745503:HU724 RS09010
gene id: 2745503:HU724_RS09010
uniprot id: A0A9E6PCX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS05630
gene id: 2745503:HU724_RS05630
uniprot id: A0A9E6PCU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS11995
gene id: 2745503:HU724_RS11995
uniprot id: A0A9E6PDX6
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS15070
gene id: 2745503:HU724_RS15070
uniprot id: A0A9E6P6C8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745503:HU724 RS00050
gene id: 2745503:HU724_RS00050
uniprot id: A0A9E6P9Q3
names: Similarity
messages: Belongs to the RutC family.

2745503:HU724 RS20360
gene id: 2745503:HU724_RS20360
uniprot id: A0A9E6P760
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2745503:HU724 RS05995
gene id: 2745503:HU724_RS05995
uniprot id: A0A9E6TNI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

2745503:HU724 RS25530
gene id: 2745503:HU724_RS25530
uniprot id: A0A9E6TLA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

2745503:HU724 RS24550
gene id: 2745503:HU724_RS24550
uniprot id: A0A9E6TLG6
names: Similarity
messages: Belongs to the histone deacetylase family.

2745503:HU724 RS03605
gene id: 2745503:HU724_RS03605
uniprot id: A0A9E6TMK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

2745503:HU724 RS26675
gene id: 2745503:HU724_RS26675
uniprot id: A0A9E6P9P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

2745503:HU724 RS18455
gene id: 2745503:HU724_RS18455
uniprot id: A0A9E6P6M8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

2745503:HU724 RS22340
gene id: 2745503:HU724_RS22340
uniprot id: A0A9E6P8Y2
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS09905
gene id: 2745503:HU724_RS09905
uniprot id: A0A9E6PEL3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

2745503:HU724 RS26290
gene id: 2745503:HU724_RS26290
uniprot id: A0A9E6P9J2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS18525
gene id: 2745503:HU724_RS18525
uniprot id: A0A9E6P6Q1
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS25175
gene id: 2745503:HU724_RS25175
uniprot id: A0A9E6TKL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

2745503:HU724 RS08735
gene id: 2745503:HU724_RS08735
uniprot id: A0A9E6TN42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

2745503:HU724 RS16815
gene id: 2745503:HU724_RS16815
uniprot id: A0A9E6P620
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS21790
gene id: 2745503:HU724_RS21790
uniprot id: A0A9E6P7V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745503:HU724 RS25350
gene id: 2745503:HU724_RS25350
uniprot id: A0A9E6P9U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2745503:HU724 RS20590
gene id: 2745503:HU724_RS20590
uniprot id: A0A9E6P786
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

2745503:HU724 RS18830
gene id: 2745503:HU724_RS18830
uniprot id: A0A9E6P7P8
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS09680
gene id: 2745503:HU724_RS09680
uniprot id: A0A9E6PDU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

2745503:HU724 RS16535
gene id: 2745503:HU724_RS16535
uniprot id: A0A9E6P6S5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2745503:HU724 RS20605
gene id: 2745503:HU724_RS20605
uniprot id: A0A9E6P7M2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2745503:HU724 RS19510
gene id: 2745503:HU724_RS19510
uniprot id: A0A9E6TK76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

2745503:HU724 RS22915
gene id: 2745503:HU724_RS22915
uniprot id: A0A9E6P837
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

2745503:HU724 RS26700
gene id: 2745503:HU724_RS26700
uniprot id: A0A9E6TKW2
names: Similarity
messages: Belongs to the peptidase C56 family.

2745503:HU724 RS13140
gene id: 2745503:HU724_RS13140
uniprot id: A0A9E6TP24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

2745503:HU724 RS23005
gene id: 2745503:HU724_RS23005
uniprot id: A0A9E6TKV4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

2745503:HU724 RS17960
gene id: 2745503:HU724_RS17960
uniprot id: A0A9E6P777
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

2745503:HU724 RS03190
gene id: 2745503:HU724_RS03190
uniprot id: A0A9E6PB29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

2745503:HU724 RS26585
gene id: 2745503:HU724_RS26585
uniprot id: A0A9E6P9Q5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS24030
gene id: 2745503:HU724_RS24030
uniprot id: A0A9E6P9E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

2745503:HU724 RS18825
gene id: 2745503:HU724_RS18825
uniprot id: A0A9E6P7N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

2745503:HU724 RS24240
gene id: 2745503:HU724_RS24240
uniprot id: A0A9E6TLE8
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

2745503:HU724 RS10735
gene id: 2745503:HU724_RS10735
uniprot id: A0A9E6PDK8
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

2745503:HU724 RS11990
gene id: 2745503:HU724_RS11990
uniprot id: A0A9E6PEM1
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

2745503:HU724 RS01560
gene id: 2745503:HU724_RS01560
uniprot id: A0A9E6TM81
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

2745503:HU724 RS00010
gene id: 2745503:HU724_RS00010
uniprot id: A0A9E6TLY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

2745503:HU724 RS25190
gene id: 2745503:HU724_RS25190
uniprot id: A0A9E6P9U2
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

2745503:HU724 RS22025
gene id: 2745503:HU724_RS22025
uniprot id: A0A9E6P8U2
names: Similarity
messages: Belongs to the Dps family.

2745503:HU724 RS04685
gene id: 2745503:HU724_RS04685
uniprot id: A0A9E6PCB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

2745503:HU724 RS02575
gene id: 2745503:HU724_RS02575
uniprot id: A0A9E6TLD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

2745503:HU724 RS06500
gene id: 2745503:HU724_RS06500
uniprot id: A0A9E6PCU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

2745503:HU724 RS09380
gene id: 2745503:HU724_RS09380
uniprot id: A0A9E6TMN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

2745503:HU724 RS17190
gene id: 2745503:HU724_RS17190
uniprot id: A0A9E6TKG0
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

2745503:HU724 RS20010
gene id: 2745503:HU724_RS20010
uniprot id: A0A9E6TL15
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2745503:HU724 RS18110
gene id: 2745503:HU724_RS18110
uniprot id: A0A9E6P7D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745503:HU724 RS26495
gene id: 2745503:HU724_RS26495
uniprot id: A0A9E6P9E5
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

2745503:HU724 RS21985
gene id: 2745503:HU724_RS21985
uniprot id: A0A9E6P848
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

2745503:HU724 RS23985
gene id: 2745503:HU724_RS23985
uniprot id: A0A9E6P8I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

2745503:HU724 RS00970
gene id: 2745503:HU724_RS00970
uniprot id: A0A9E6PAZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

2745503:HU724 RS10180
gene id: 2745503:HU724_RS10180
uniprot id: A0A9E6TNQ0
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS27150
gene id: 2745503:HU724_RS27150
uniprot id: A0A9E6PAZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

2745503:HU724 RS10845
gene id: 2745503:HU724_RS10845
uniprot id: A0A9E6TMX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2745503:HU724 RS05210
gene id: 2745503:HU724_RS05210
uniprot id: A0A9E6PD50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

2745503:HU724 RS26395
gene id: 2745503:HU724_RS26395
uniprot id: A0A9E6TLE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

2745503:HU724 RS00950
gene id: 2745503:HU724_RS00950
uniprot id: A0A9E6TM17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

2745503:HU724 RS09810
gene id: 2745503:HU724_RS09810
uniprot id: A0A9E6PD12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

2745503:HU724 RS18080
gene id: 2745503:HU724_RS18080
uniprot id: A0A9E6TKC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

2745503:HU724 RS25255
gene id: 2745503:HU724_RS25255
uniprot id: A0A9E6TL92
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2745503:HU724 RS01215
gene id: 2745503:HU724_RS01215
uniprot id: A0A9E6PA57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

2745503:HU724 RS17460
gene id: 2745503:HU724_RS17460
uniprot id: A0A9E6P6B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

2745503:HU724 RS00130
gene id: 2745503:HU724_RS00130
uniprot id: A0A9E6PAS9
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

2745503:HU724 RS15600
gene id: 2745503:HU724_RS15600
uniprot id: A0A9E6P6K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

2745503:HU724 RS05340
gene id: 2745503:HU724_RS05340
uniprot id: A0A9E6PBM5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

2745503:HU724 RS22895
gene id: 2745503:HU724_RS22895
uniprot id: A0A9E6P993
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

2745503:HU724 RS18905
gene id: 2745503:HU724_RS18905
uniprot id: A0A9E6P7P6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745503:HU724 RS25230
gene id: 2745503:HU724_RS25230
uniprot id: A0A9E6P8Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2745503:HU724 RS03545
gene id: 2745503:HU724_RS03545
uniprot id: A0A9E6PBW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

2745503:HU724 RS25320
gene id: 2745503:HU724_RS25320
uniprot id: A0A9E6TLJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2745503:HU724 RS04340
gene id: 2745503:HU724_RS04340
uniprot id: A0A9E6PC29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

2745503:HU724 RS05865
gene id: 2745503:HU724_RS05865
uniprot id: A0A9E6PBT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

2745503:HU724 RS23075
gene id: 2745503:HU724_RS23075
uniprot id: A0A9E6P857
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

2745503:HU724 RS24685
gene id: 2745503:HU724_RS24685
uniprot id: A0A9E6P8S2
names: Similarity
messages: Belongs to the PhoH family.

2745503:HU724 RS01835
gene id: 2745503:HU724_RS01835
uniprot id: A0A9E6TL98
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2745503:HU724 RS08405
gene id: 2745503:HU724_RS08405
uniprot id: A0A9E6PDD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2745503:HU724 RS16935
gene id: 2745503:HU724_RS16935
uniprot id: A0A9E6TK47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS07480
gene id: 2745503:HU724_RS07480
uniprot id: A0A9E6PD01
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS21660
gene id: 2745503:HU724_RS21660
uniprot id: A0A9E6P7N3
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

2745503:HU724 RS08810
gene id: 2745503:HU724_RS08810
uniprot id: A0A9E6TN48
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

2745503:HU724 RS06150
gene id: 2745503:HU724_RS06150
uniprot id: A0A9E6TNK0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

2745503:HU724 RS22950
gene id: 2745503:HU724_RS22950
uniprot id: A0A9E6P8U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

2745503:HU724 RS03130
gene id: 2745503:HU724_RS03130
uniprot id: A0A9E6TMF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
messages: Cell membrane
messages: K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.

2745503:HU724 RS01000
gene id: 2745503:HU724_RS01000
uniprot id: A0A9E6PAD0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2745503:HU724 RS13010
gene id: 2745503:HU724_RS13010
uniprot id: A0A9E6PEU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS17990
gene id: 2745503:HU724_RS17990
uniprot id: A0A9E6P7G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

2745503:HU724 RS17215
gene id: 2745503:HU724_RS17215
uniprot id: A0A9E6P779
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

2745503:HU724 RS02580
gene id: 2745503:HU724_RS02580
uniprot id: A0A9E6TM10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

2745503:HU724 RS24790
gene id: 2745503:HU724_RS24790
uniprot id: A0A9E6TLI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

2745503:HU724 RS19410
gene id: 2745503:HU724_RS19410
uniprot id: A0A9E6P806
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

2745503:HU724 RS03685
gene id: 2745503:HU724_RS03685
uniprot id: A0A9E6TML3
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

2745503:HU724 RS22920
gene id: 2745503:HU724_RS22920
uniprot id: A0A9E6P8E9
names: Similarity
messages: Belongs to the YfgM family.

2745503:HU724 RS08775
gene id: 2745503:HU724_RS08775
uniprot id: A0A9E6PCU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

2745503:HU724 RS20390
gene id: 2745503:HU724_RS20390
uniprot id: A0A9E6TJR7
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

2745503:HU724 RS04785
gene id: 2745503:HU724_RS04785
uniprot id: A0A9E6PC75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

2745503:HU724 RS02765
gene id: 2745503:HU724_RS02765
uniprot id: A0A9E6PBI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2745503:HU724 RS19365
gene id: 2745503:HU724_RS19365
uniprot id: A0A9E6TKD0
names: Similarity
messages: Belongs to the MlaA family.

2745503:HU724 RS27210
gene id: 2745503:HU724_RS27210
uniprot id: A0A9E6PAN9
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

2745503:HU724 RS25585
gene id: 2745503:HU724_RS25585
uniprot id: A0A9E6P9J4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

2745503:HU724 RS06770
gene id: 2745503:HU724_RS06770
uniprot id: A0A9E6PCN5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

2745503:HU724 RS02950
gene id: 2745503:HU724_RS02950
uniprot id: A0A9E6PB06
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS25395
gene id: 2745503:HU724_RS25395
uniprot id: A0A9E6TLJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

2745503:HU724 RS23300
gene id: 2745503:HU724_RS23300
uniprot id: A0A9E6P9B9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

2745503:HU724 RS01370
gene id: 2745503:HU724_RS01370
uniprot id: A0A9E6PA77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS23225
gene id: 2745503:HU724_RS23225
uniprot id: A0A9E6P9K1
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

2745503:HU724 RS05850
gene id: 2745503:HU724_RS05850
uniprot id: A0A9E6PCW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

2745503:HU724 RS17950
gene id: 2745503:HU724_RS17950
uniprot id: A0A9E6TKK7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

2745503:HU724 RS08510
gene id: 2745503:HU724_RS08510
uniprot id: A0A9E6TP03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

2745503:HU724 RS06355
gene id: 2745503:HU724_RS06355
uniprot id: A0A9E6PCA5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS09630
gene id: 2745503:HU724_RS09630
uniprot id: A0A9E6TN86
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745503:HU724 RS18170
gene id: 2745503:HU724_RS18170
uniprot id: A0A9E6TK55
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS01505
gene id: 2745503:HU724_RS01505
uniprot id: A0A9E6TMQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS17575
gene id: 2745503:HU724_RS17575
uniprot id: A0A9E6P718
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

2745503:HU724 RS21065
gene id: 2745503:HU724_RS21065
uniprot id: A0A9E6P8Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

2745503:HU724 RS25675
gene id: 2745503:HU724_RS25675
uniprot id: A0A9E6TKP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

2745503:HU724 RS25705
gene id: 2745503:HU724_RS25705
uniprot id: A0A9E6P972
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

2745503:HU724 RS14860
gene id: 2745503:HU724_RS14860
uniprot id: A0A9E6P5D1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745503:HU724 RS10805
gene id: 2745503:HU724_RS10805
uniprot id: A0A9E6PE62
names: Subcellular Location Annotation
messages: Cytoplasm

2745503:HU724 RS18695
gene id: 2745503:HU724_RS18695
uniprot id: A0A9E6P7R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

2745503:HU724 RS18050
gene id: 2745503:HU724_RS18050
uniprot id: A0A9E6P7M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745503:HU724 RS09120
gene id: 2745503:HU724_RS09120
uniprot id: A0A9E6PDI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745503:HU724 RS27100
gene id: 2745503:HU724_RS27100
uniprot id: A0A9E6TLI3
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

2745503:HU724 RS21385
gene id: 2745503:HU724_RS21385
uniprot id: A0A9E6P8A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

2745503:HU724 RS23580
gene id: 2745503:HU724_RS23580
uniprot id: A0A9E6TKY7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

2745503:HU724 RS07025
gene id: 2745503:HU724_RS07025
uniprot id: A0A9E6TMT8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS07085
gene id: 2745503:HU724_RS07085
uniprot id: A0A9E6TN84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

2745503:HU724 RS02295
gene id: 2745503:HU724_RS02295
uniprot id: A0A9E6PF36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

2745503:HU724 RS20400
gene id: 2745503:HU724_RS20400
uniprot id: A0A9E6TL37
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

2745503:HU724 RS07690
gene id: 2745503:HU724_RS07690
uniprot id: A0A9E6PD76
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

2745503:HU724 RS02175
gene id: 2745503:HU724_RS02175
uniprot id: A0A9E6PBB9
names: Similarity
messages: Belongs to the thioesterase PaaI family.

2745503:HU724 RS02870
gene id: 2745503:HU724_RS02870
uniprot id: A0A9E6PAZ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2745503:HU724 RS02800
gene id: 2745503:HU724_RS02800
uniprot id: A0A9E6PB92
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

2745503:HU724 RS01235
gene id: 2745503:HU724_RS01235
uniprot id: A0A9E6PBH9
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS02430
gene id: 2745503:HU724_RS02430
uniprot id: A0A9E6PBL2
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS22675
gene id: 2745503:HU724_RS22675
uniprot id: A0A9E6P964
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

2745503:HU724 RS24305
gene id: 2745503:HU724_RS24305
uniprot id: A0A9E6P8M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS02710
gene id: 2745503:HU724_RS02710
uniprot id: A0A9E6PAN0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2745503:HU724 RS21875
gene id: 2745503:HU724_RS21875
uniprot id: A0A9E6P861
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

2745503:HU724 RS23020
gene id: 2745503:HU724_RS23020
uniprot id: A0A9E6TLN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

2745503:HU724 RS20830
gene id: 2745503:HU724_RS20830
uniprot id: A0A9E6P8H8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2745503:HU724 RS01210
gene id: 2745503:HU724_RS01210
uniprot id: A0A9E6PB10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ivy family.
messages: Periplasm

2745503:HU724 RS23125
gene id: 2745503:HU724_RS23125
uniprot id: A0A9E6P987
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS25360
gene id: 2745503:HU724_RS25360
uniprot id: A0A9E6PA11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

2745503:HU724 RS06510
gene id: 2745503:HU724_RS06510
uniprot id: A0A9E6PBY5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

2745503:HU724 RS26545
gene id: 2745503:HU724_RS26545
uniprot id: A0A9E6TLF0
names: Similarity
messages: Belongs to the YggT family.

2745503:HU724 RS23355
gene id: 2745503:HU724_RS23355
uniprot id: A0A9E6TLQ8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

2745503:HU724 RS25450
gene id: 2745503:HU724_RS25450
uniprot id: A0A9E6P945
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

2745503:HU724 RS04770
gene id: 2745503:HU724_RS04770
uniprot id: A0A9E6PCF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745503:HU724 RS22925
gene id: 2745503:HU724_RS22925
uniprot id: A0A9E6TL82
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

2745503:HU724 RS05280
gene id: 2745503:HU724_RS05280
uniprot id: A0A9E6PBK1
names: Function
messages: Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions.

2745503:HU724 RS08145
gene id: 2745503:HU724_RS08145
uniprot id: A0A9E6PCK9
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS22930
gene id: 2745503:HU724_RS22930
uniprot id: A0A9E6TKU9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

2745503:HU724 RS13450
gene id: 2745503:HU724_RS13450
uniprot id: A0A9E6TNE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

2745503:HU724 RS25685
gene id: 2745503:HU724_RS25685
uniprot id: A0A9E6TM42
names: Similarity
messages: Belongs to the UPF0229 family.

2745503:HU724 RS22805
gene id: 2745503:HU724_RS22805
uniprot id: A0A9E6P954
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

2745503:HU724 RS03550
gene id: 2745503:HU724_RS03550
uniprot id: A0A9E6PBZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

2745503:HU724 RS26725
gene id: 2745503:HU724_RS26725
uniprot id: A0A9E6PAB3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS05060
gene id: 2745503:HU724_RS05060
uniprot id: A0A9E6PC05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS07855
gene id: 2745503:HU724_RS07855
uniprot id: A0A9E6PCE7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

2745503:HU724 RS25840
gene id: 2745503:HU724_RS25840
uniprot id: A0A9E6TLL5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS26390
gene id: 2745503:HU724_RS26390
uniprot id: A0A9E6TKT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

2745503:HU724 RS26340
gene id: 2745503:HU724_RS26340
uniprot id: A0A9E6P9D3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

2745503:HU724 RS16920
gene id: 2745503:HU724_RS16920
uniprot id: A0A9E6P708
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS22960
gene id: 2745503:HU724_RS22960
uniprot id: A0A9E6P966
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

2745503:HU724 RS19915
gene id: 2745503:HU724_RS19915
uniprot id: A0A9E6TKP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS00920
gene id: 2745503:HU724_RS00920
uniprot id: A0A9E6PAC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

2745503:HU724 RS05250
gene id: 2745503:HU724_RS05250
uniprot id: A0A9E6PCI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS10135
gene id: 2745503:HU724_RS10135
uniprot id: A0A9E6PDC2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

2745503:HU724 RS13455
gene id: 2745503:HU724_RS13455
uniprot id: A0A9E6TNY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS22965
gene id: 2745503:HU724_RS22965
uniprot id: A0A9E6P8A7
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

2745503:HU724 RS09015
gene id: 2745503:HU724_RS09015
uniprot id: A0A9E6PEC6
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS14920
gene id: 2745503:HU724_RS14920
uniprot id: A0A9E6P5E1
names: Similarity
messages: Belongs to the glutamine synthetase family.

2745503:HU724 RS24455
gene id: 2745503:HU724_RS24455
uniprot id: A0A9E6P8N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS08575
gene id: 2745503:HU724_RS08575
uniprot id: A0A9E6TMI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

2745503:HU724 RS26980
gene id: 2745503:HU724_RS26980
uniprot id: A0A9E6PAX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745503:HU724 RS03145
gene id: 2745503:HU724_RS03145
uniprot id: A0A9E6TN06
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

2745503:HU724 RS21260
gene id: 2745503:HU724_RS21260
uniprot id: A0A9E6TKY2
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

2745503:HU724 RS19975
gene id: 2745503:HU724_RS19975
uniprot id: A0A9E6P873
names: Similarity
messages: Belongs to the glutathione peroxidase family.

2745503:HU724 RS23325
gene id: 2745503:HU724_RS23325
uniprot id: A0A9E6P886
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

2745503:HU724 RS05255
gene id: 2745503:HU724_RS05255
uniprot id: A0A9E6PCL6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

2745503:HU724 RS08780
gene id: 2745503:HU724_RS08780
uniprot id: A0A9E6PEA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

2745503:HU724 RS27785
gene id: 2745503:HU724_RS27785
uniprot id: A0A9E6P7Y9
names: Subcellular Location Annotation
messages: Cytoplasm

2745503:HU724 RS15915
gene id: 2745503:HU724_RS15915
uniprot id: A0A9E6P5S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

2745503:HU724 RS00230
gene id: 2745503:HU724_RS00230
uniprot id: A0A9E6PA20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

2745503:HU724 RS25265
gene id: 2745503:HU724_RS25265
uniprot id: A0A9E6P9V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

2745503:HU724 RS12865
gene id: 2745503:HU724_RS12865
uniprot id: A0A9E6TP84
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

2745503:HU724 RS25720
gene id: 2745503:HU724_RS25720
uniprot id: A0A9E6P951
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2745503:HU724 RS16515
gene id: 2745503:HU724_RS16515
uniprot id: A0A9E6TJU9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2745503:HU724 RS26155
gene id: 2745503:HU724_RS26155
uniprot id: A0A9E6TLD3
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

2745503:HU724 RS03985
gene id: 2745503:HU724_RS03985
uniprot id: A0A9E6PCK8
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

2745503:HU724 RS09225
gene id: 2745503:HU724_RS09225
uniprot id: A0A9E6TP42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

2745503:HU724 RS22445
gene id: 2745503:HU724_RS22445
uniprot id: A0A9E6P927
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2745503:HU724 RS20820
gene id: 2745503:HU724_RS20820
uniprot id: A0A9E6P7S0
names: Similarity
messages: Belongs to the peptidase S49 family.

2745503:HU724 RS06055
gene id: 2745503:HU724_RS06055
uniprot id: A0A9E6TMZ2
names: Similarity
messages: Belongs to the RecJ family.

2745503:HU724 RS05835
gene id: 2745503:HU724_RS05835
uniprot id: A0A9E6TM11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

2745503:HU724 RS00200
gene id: 2745503:HU724_RS00200
uniprot id: A0A9E6PAN4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

2745503:HU724 RS25420
gene id: 2745503:HU724_RS25420
uniprot id: A0A9E6P935
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2745503:HU724 RS25715
gene id: 2745503:HU724_RS25715
uniprot id: A0A9E6P9F2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

2745503:HU724 RS08360
gene id: 2745503:HU724_RS08360
uniprot id: A0A9E6TNY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2745503:HU724 RS24875
gene id: 2745503:HU724_RS24875
uniprot id: A0A9E6TKJ6
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

2745503:HU724 RS22035
gene id: 2745503:HU724_RS22035
uniprot id: A0A9E6P915
names: Similarity
messages: Belongs to the SlyX family.

2745503:HU724 RS01255
gene id: 2745503:HU724_RS01255
uniprot id: A0A9E6TM39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

2745503:HU724 RS09885
gene id: 2745503:HU724_RS09885
uniprot id: A0A9E6PD21
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

2745503:HU724 RS11945
gene id: 2745503:HU724_RS11945
uniprot id: A0A9E6PF16
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS01400
gene id: 2745503:HU724_RS01400
uniprot id: A0A9E6PAS0
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

2745503:HU724 RS23340
gene id: 2745503:HU724_RS23340
uniprot id: A0A9E6TKY0
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

2745503:HU724 RS09255
gene id: 2745503:HU724_RS09255
uniprot id: A0A9E6PDQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

2745503:HU724 RS08435
gene id: 2745503:HU724_RS08435
uniprot id: A0A9E6TNZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

2745503:HU724 RS02490
gene id: 2745503:HU724_RS02490
uniprot id: A0A9E6TMB3
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

2745503:HU724 RS23365
gene id: 2745503:HU724_RS23365
uniprot id: A0A9E6P9B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2745503:HU724 RS00205
gene id: 2745503:HU724_RS00205
uniprot id: A0A9E6P9S1
names: Similarity
messages: Belongs to the RutC family.

2745503:HU724 RS09470
gene id: 2745503:HU724_RS09470
uniprot id: A0A9E6TMP2
names: Similarity
messages: Belongs to the UPF0145 family.

2745503:HU724 RS18025
gene id: 2745503:HU724_RS18025
uniprot id: A0A9E6TKL2
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

2745503:HU724 RS19735
gene id: 2745503:HU724_RS19735
uniprot id: A0A9E6P7D1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS06345
gene id: 2745503:HU724_RS06345
uniprot id: A0A9E6PBW6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

2745503:HU724 RS01155
gene id: 2745503:HU724_RS01155
uniprot id: A0A9E6PA36
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS18045
gene id: 2745503:HU724_RS18045
uniprot id: A0A9E6P6G3
names: Cofactor
messages: Can also use Mn(2+) ion.

2745503:HU724 RS23715
gene id: 2745503:HU724_RS23715
uniprot id: A0A9E6P8P5
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS06885
gene id: 2745503:HU724_RS06885
uniprot id: A0A9E6PD72
names: Similarity
messages: Belongs to the UPF0225 family.

2745503:HU724 RS17520
gene id: 2745503:HU724_RS17520
uniprot id: A0A9E6P6P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

2745503:HU724 RS00710
gene id: 2745503:HU724_RS00710
uniprot id: A0A9E6PAJ0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

2745503:HU724 RS24145
gene id: 2745503:HU724_RS24145
uniprot id: A0A9E6P8K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

2745503:HU724 RS04810
gene id: 2745503:HU724_RS04810
uniprot id: A0A9E6PD00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2745503:HU724 RS08495
gene id: 2745503:HU724_RS08495
uniprot id: A0A9E6TNE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

2745503:HU724 RS15935
gene id: 2745503:HU724_RS15935
uniprot id: A0A9E6P652
names: Similarity
messages: Belongs to the UDPGP type 2 family.

2745503:HU724 RS26540
gene id: 2745503:HU724_RS26540
uniprot id: A0A9E6TKU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

2745503:HU724 RS17320
gene id: 2745503:HU724_RS17320
uniprot id: A0A9E6TK73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP.
messages: Membrane

2745503:HU724 RS09330
gene id: 2745503:HU724_RS09330
uniprot id: A0A9E6PCV5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

2745503:HU724 RS14555
gene id: 2745503:HU724_RS14555
uniprot id: A0A9E6P5B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS20065
gene id: 2745503:HU724_RS20065
uniprot id: A0A9E6P7F0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS12935
gene id: 2745503:HU724_RS12935
uniprot id: A0A9E6PFC9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

2745503:HU724 RS27415
gene id: 2745503:HU724_RS27415
uniprot id: A0A9E6TMF4
names: Similarity
messages: Belongs to the P(II) protein family.

2745503:HU724 RS02195
gene id: 2745503:HU724_RS02195
uniprot id: A0A9E6PAH5
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

2745503:HU724 RS09570
gene id: 2745503:HU724_RS09570
uniprot id: A0A9E6PE71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

2745503:HU724 RS08585
gene id: 2745503:HU724_RS08585
uniprot id: A0A9E6TP06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

2745503:HU724 RS05985
gene id: 2745503:HU724_RS05985
uniprot id: A0A9E6TM20
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

2745503:HU724 RS25285
gene id: 2745503:HU724_RS25285
uniprot id: A0A9E6PA02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

2745503:HU724 RS24840
gene id: 2745503:HU724_RS24840
uniprot id: A0A9E6P988
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS24160
gene id: 2745503:HU724_RS24160
uniprot id: A0A9E6P8U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

2745503:HU724 RS04015
gene id: 2745503:HU724_RS04015
uniprot id: A0A9E6TMA2
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

2745503:HU724 RS26275
gene id: 2745503:HU724_RS26275
uniprot id: A0A9E6P9L8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

2745503:HU724 RS04975
gene id: 2745503:HU724_RS04975
uniprot id: A0A9E6PD16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS04215
gene id: 2745503:HU724_RS04215
uniprot id: A0A9E6PCN7
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

2745503:HU724 RS08195
gene id: 2745503:HU724_RS08195
uniprot id: A0A9E6TND0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

2745503:HU724 RS02705
gene id: 2745503:HU724_RS02705
uniprot id: A0A9E6PAZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745503:HU724 RS04690
gene id: 2745503:HU724_RS04690
uniprot id: A0A9E6PCE1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

2745503:HU724 RS10250
gene id: 2745503:HU724_RS10250
uniprot id: A0A9E6TPD5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS18450
gene id: 2745503:HU724_RS18450
uniprot id: A0A9E6P7M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2745503:HU724 RS09375
gene id: 2745503:HU724_RS09375
uniprot id: A0A9E6TNK3
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS23235
gene id: 2745503:HU724_RS23235
uniprot id: A0A9E6P8I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

2745503:HU724 RS21960
gene id: 2745503:HU724_RS21960
uniprot id: A0A9E6P7P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2745503:HU724 RS04350
gene id: 2745503:HU724_RS04350
uniprot id: A0A9E6PCD3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2745503:HU724 RS26690
gene id: 2745503:HU724_RS26690
uniprot id: A0A9E6TLR1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

2745503:HU724 RS25355
gene id: 2745503:HU724_RS25355
uniprot id: A0A9E6P935
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2745503:HU724 RS20875
gene id: 2745503:HU724_RS20875
uniprot id: A0A9E6P8F4
names: Similarity
messages: Belongs to the UPF0434 family.

2745503:HU724 RS07540
gene id: 2745503:HU724_RS07540
uniprot id: A0A9E6PCA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2745503:HU724 RS24395
gene id: 2745503:HU724_RS24395
uniprot id: A0A9E6P8X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

2745503:HU724 RS23250
gene id: 2745503:HU724_RS23250
uniprot id: A0A9E6TK97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

2745503:HU724 RS23900
gene id: 2745503:HU724_RS23900
uniprot id: A0A9E6P9T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

2745503:HU724 RS00580
gene id: 2745503:HU724_RS00580
uniprot id: A0A9E6TLN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS03750
gene id: 2745503:HU724_RS03750
uniprot id: A0A9E6PB99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

2745503:HU724 RS25260
gene id: 2745503:HU724_RS25260
uniprot id: A0A9E6TM22
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2745503:HU724 RS25405
gene id: 2745503:HU724_RS25405
uniprot id: A0A9E6TLA0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

2745503:HU724 RS16250
gene id: 2745503:HU724_RS16250
uniprot id: A0A9E6P6U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

2745503:HU724 RS07155
gene id: 2745503:HU724_RS07155
uniprot id: A0A9E6PCK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

2745503:HU724 RS22870
gene id: 2745503:HU724_RS22870
uniprot id: A0A9E6TLM2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

2745503:HU724 RS01695
gene id: 2745503:HU724_RS01695
uniprot id: A0A9E6PBE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

2745503:HU724 RS02625
gene id: 2745503:HU724_RS02625
uniprot id: A0A9E6PAY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

2745503:HU724 RS08890
gene id: 2745503:HU724_RS08890
uniprot id: A0A9E6TP25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

2745503:HU724 RS02860
gene id: 2745503:HU724_RS02860
uniprot id: A0A9E6PAQ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

2745503:HU724 RS06240
gene id: 2745503:HU724_RS06240
uniprot id: A0A9E6PD07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS18445
gene id: 2745503:HU724_RS18445
uniprot id: A0A9E6P6K3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2745503:HU724 RS26435
gene id: 2745503:HU724_RS26435
uniprot id: A0A9E6P9C9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MdcC family.
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm
messages: Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.

2745503:HU724 RS25580
gene id: 2745503:HU724_RS25580
uniprot id: A0A9E6P934
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

2745503:HU724 RS21395
gene id: 2745503:HU724_RS21395
uniprot id: A0A9E6P8L5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

2745503:HU724 RS25025
gene id: 2745503:HU724_RS25025
uniprot id: A0A9E6TKK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

2745503:HU724 RS20405
gene id: 2745503:HU724_RS20405
uniprot id: A0A9E6P7Y8
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

2745503:HU724 RS17110
gene id: 2745503:HU724_RS17110
uniprot id: A0A9E6TPF8
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

2745503:HU724 RS04045
gene id: 2745503:HU724_RS04045
uniprot id: A0A9E6PC92
names: Similarity
messages: Belongs to the SUI1 family.

2745503:HU724 RS06850
gene id: 2745503:HU724_RS06850
uniprot id: A0A9E6PCG4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2745503:HU724 RS21110
gene id: 2745503:HU724_RS21110
uniprot id: A0A9E6TJW3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

2745503:HU724 RS14325
gene id: 2745503:HU724_RS14325
uniprot id: A0A9E6P587
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

2745503:HU724 RS14705
gene id: 2745503:HU724_RS14705
uniprot id: A0A9E6P5C2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS08770
gene id: 2745503:HU724_RS08770
uniprot id: A0A9E6PDE6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

2745503:HU724 RS11455
gene id: 2745503:HU724_RS11455
uniprot id: A0A9E6PEF1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

2745503:HU724 RS22985
gene id: 2745503:HU724_RS22985
uniprot id: A0A9E6P9G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

2745503:HU724 RS12030
gene id: 2745503:HU724_RS12030
uniprot id: A0A9E6TP33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

2745503:HU724 RS01335
gene id: 2745503:HU724_RS01335
uniprot id: A0A9E6TM43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

2745503:HU724 RS11315
gene id: 2745503:HU724_RS11315
uniprot id: A0A9E6PDR6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

2745503:HU724 RS07415
gene id: 2745503:HU724_RS07415
uniprot id: A0A9E6TMW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745503:HU724 RS25165
gene id: 2745503:HU724_RS25165
uniprot id: A0A9E6TLL0
names: Similarity
messages: Belongs to the PspA/IM30 family.

2745503:HU724 RS08400
gene id: 2745503:HU724_RS08400
uniprot id: A0A9E6PE67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

2745503:HU724 RS21090
gene id: 2745503:HU724_RS21090
uniprot id: A0A9E6P7T6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

2745503:HU724 RS07990
gene id: 2745503:HU724_RS07990
uniprot id: A0A9E6PCI7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

2745503:HU724 RS02615
gene id: 2745503:HU724_RS02615
uniprot id: A0A9E6PAP9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

2745503:HU724 RS05195
gene id: 2745503:HU724_RS05195
uniprot id: A0A9E6PCN8
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

2745503:HU724 RS09215
gene id: 2745503:HU724_RS09215
uniprot id: A0A9E6TMM4
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

2745503:HU724 RS00925
gene id: 2745503:HU724_RS00925
uniprot id: A0A9E6PA07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

2745503:HU724 RS20090
gene id: 2745503:HU724_RS20090
uniprot id: A0A9E6TL18
names: Similarity
messages: Belongs to the universal stress protein A family.

2745503:HU724 RS03320
gene id: 2745503:HU724_RS03320
uniprot id: A0A9E6PBW5
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

2745503:HU724 RS10280
gene id: 2745503:HU724_RS10280
uniprot id: A0A9E6PEM6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS00185
gene id: 2745503:HU724_RS00185
uniprot id: A0A9E6TMG8
names: Similarity
messages: Belongs to the YicC/YloC family.

2745503:HU724 RS05625
gene id: 2745503:HU724_RS05625
uniprot id: A0A9E6PCN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AlgJ family.
messages: Cell inner membrane
messages: Periplasm

2745503:HU724 RS21615
gene id: 2745503:HU724_RS21615
uniprot id: A0A9E6TLB4
names: Similarity
messages: Belongs to the YciI family.

2745503:HU724 RS20795
gene id: 2745503:HU724_RS20795
uniprot id: A0A9E6P8C9
names: Similarity
messages: Belongs to the fabD family.

2745503:HU724 RS25295
gene id: 2745503:HU724_RS25295
uniprot id: A0A9E6P904
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2745503:HU724 RS18600
gene id: 2745503:HU724_RS18600
uniprot id: A0A9E6P6R1
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS03340
gene id: 2745503:HU724_RS03340
uniprot id: A0A9E6PB84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS21360
gene id: 2745503:HU724_RS21360
uniprot id: A0A9E6TKM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

2745503:HU724 RS03395
gene id: 2745503:HU724_RS03395
uniprot id: A0A9E6PBX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

2745503:HU724 RS26930
gene id: 2745503:HU724_RS26930
uniprot id: A0A9E6TKX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

2745503:HU724 RS06805
gene id: 2745503:HU724_RS06805
uniprot id: A0A9E6PD64
names: Subcellular Location Annotation
messages: Cytoplasm

2745503:HU724 RS01870
gene id: 2745503:HU724_RS01870
uniprot id: A0A9E6PBD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

2745503:HU724 RS03440
gene id: 2745503:HU724_RS03440
uniprot id: A0A9E6TMJ6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

2745503:HU724 RS23645
gene id: 2745503:HU724_RS23645
uniprot id: A0A9E6TL09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PagL family.
messages: Cell outer membrane
messages: Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety.
messages: Homodimer.

2745503:HU724 RS27225
gene id: 2745503:HU724_RS27225
uniprot id: A0A9E6PB03
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

2745503:HU724 RS00140
gene id: 2745503:HU724_RS00140
uniprot id: A0A9E6P9R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

2745503:HU724 RS04730
gene id: 2745503:HU724_RS04730
uniprot id: A0A9E6TPE8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

2745503:HU724 RS05130
gene id: 2745503:HU724_RS05130
uniprot id: A0A9E6PBJ1
names: Similarity
messages: Belongs to the peptidase U62 family.

2745503:HU724 RS05860
gene id: 2745503:HU724_RS05860
uniprot id: A0A9E6PCL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

2745503:HU724 RS09800
gene id: 2745503:HU724_RS09800
uniprot id: A0A9E6PE91
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

2745503:HU724 RS04795
gene id: 2745503:HU724_RS04795
uniprot id: A0A9E6PCI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

2745503:HU724 RS06350
gene id: 2745503:HU724_RS06350
uniprot id: A0A9E6PDJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

2745503:HU724 RS23345
gene id: 2745503:HU724_RS23345
uniprot id: A0A9E6TKA0
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

2745503:HU724 RS11880
gene id: 2745503:HU724_RS11880
uniprot id: A0A9E6TP08
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS08325
gene id: 2745503:HU724_RS08325
uniprot id: A0A9E6PE58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

2745503:HU724 RS23115
gene id: 2745503:HU724_RS23115
uniprot id: A0A9E6P8W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

2745503:HU724 RS22095
gene id: 2745503:HU724_RS22095
uniprot id: A0A9E6P8V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

2745503:HU724 RS02915
gene id: 2745503:HU724_RS02915
uniprot id: A0A9E6PBR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

2745503:HU724 RS21455
gene id: 2745503:HU724_RS21455
uniprot id: A0A9E6TKM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS00570
gene id: 2745503:HU724_RS00570
uniprot id: A0A9E6TLZ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS11750
gene id: 2745503:HU724_RS11750
uniprot id: A0A9E6PET2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2745503:HU724 RS16495
gene id: 2745503:HU724_RS16495
uniprot id: A0A9E6P6C9
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS20160
gene id: 2745503:HU724_RS20160
uniprot id: A0A9E6TKI1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

2745503:HU724 RS01010
gene id: 2745503:HU724_RS01010
uniprot id: A0A9E6PBF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

2745503:HU724 RS27125
gene id: 2745503:HU724_RS27125
uniprot id: A0A9E6PAG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

2745503:HU724 RS25600
gene id: 2745503:HU724_RS25600
uniprot id: A0A9E6TKP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745503:HU724 RS25030
gene id: 2745503:HU724_RS25030
uniprot id: A0A9E6TL75
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

2745503:HU724 RS01380
gene id: 2745503:HU724_RS01380
uniprot id: A0A9E6PAI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

2745503:HU724 RS06360
gene id: 2745503:HU724_RS06360
uniprot id: A0A9E6PCI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

2745503:HU724 RS04250
gene id: 2745503:HU724_RS04250
uniprot id: A0A9E6TN77
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745503:HU724 RS08695
gene id: 2745503:HU724_RS08695
uniprot id: A0A9E6PDE1
names: Similarity
messages: Belongs to the MlaA family.

2745503:HU724 RS21475
gene id: 2745503:HU724_RS21475
uniprot id: A0A9E6P8M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

2745503:HU724 RS04050
gene id: 2745503:HU724_RS04050
uniprot id: A0A9E6PBN5
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

2745503:HU724 RS03355
gene id: 2745503:HU724_RS03355
uniprot id: A0A9E6PB48
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

2745503:HU724 RS07965
gene id: 2745503:HU724_RS07965
uniprot id: A0A9E6TMZ3
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

2745503:HU724 RS22555
gene id: 2745503:HU724_RS22555
uniprot id: A0A9E6TLI2
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

2745503:HU724 RS20415
gene id: 2745503:HU724_RS20415
uniprot id: A0A9E6P884
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

2745503:HU724 RS20870
gene id: 2745503:HU724_RS20870
uniprot id: A0A9E6P843
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

2745503:HU724 RS22060
gene id: 2745503:HU724_RS22060
uniprot id: A0A9E6P858
names: Similarity
messages: Belongs to the UPF0234 family.

2745503:HU724 RS04675
gene id: 2745503:HU724_RS04675
uniprot id: A0A9E6TME4
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

2745503:HU724 RS18105
gene id: 2745503:HU724_RS18105
uniprot id: A0A9E6P750
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

2745503:HU724 RS18280
gene id: 2745503:HU724_RS18280
uniprot id: A0A9E6P6W6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745503:HU724 RS02515
gene id: 2745503:HU724_RS02515
uniprot id: A0A9E6PBL9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

2745503:HU724 RS04080
gene id: 2745503:HU724_RS04080
uniprot id: A0A9E6TML5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS02775
gene id: 2745503:HU724_RS02775
uniprot id: A0A9E6PBS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2745503:HU724 RS10955
gene id: 2745503:HU724_RS10955
uniprot id: A0A9E6PE47
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS21780
gene id: 2745503:HU724_RS21780
uniprot id: A0A9E6P8R7
names: Similarity
messages: Belongs to the OprB family.

2745503:HU724 RS14820
gene id: 2745503:HU724_RS14820
uniprot id: A0A9E6TJJ3
names: Similarity
messages: Belongs to the EfeM/EfeO family.

2745503:HU724 RS20085
gene id: 2745503:HU724_RS20085
uniprot id: A0A9E6TKH6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS21195
gene id: 2745503:HU724_RS21195
uniprot id: A0A9E6TJW8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

2745503:HU724 RS23120
gene id: 2745503:HU724_RS23120
uniprot id: A0A9E6P998
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane
messages: The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains.

2745503:HU724 RS11410
gene id: 2745503:HU724_RS11410
uniprot id: A0A9E6TNZ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

2745503:HU724 RS10235
gene id: 2745503:HU724_RS10235
uniprot id: A0A9E6PEQ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS21950
gene id: 2745503:HU724_RS21950
uniprot id: A0A9E6P905
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS18685
gene id: 2745503:HU724_RS18685
uniprot id: A0A9E6P706
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

2745503:HU724 RS06505
gene id: 2745503:HU724_RS06505
uniprot id: A0A9E6PCI1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2745503:HU724 RS18085
gene id: 2745503:HU724_RS18085
uniprot id: A0A9E6TJZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745503:HU724 RS19290
gene id: 2745503:HU724_RS19290
uniprot id: A0A9E6TKC8
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

2745503:HU724 RS26305
gene id: 2745503:HU724_RS26305
uniprot id: A0A9E6TLN8
names: PTM
messages: Binds 1 heme group per subunit.

2745503:HU724 RS08605
gene id: 2745503:HU724_RS08605
uniprot id: A0A9E6PCQ8
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

2745503:HU724 RS00930
gene id: 2745503:HU724_RS00930
uniprot id: A0A9E6PBE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

2745503:HU724 RS25240
gene id: 2745503:HU724_RS25240
uniprot id: A0A9E6TLL4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2745503:HU724 RS25890
gene id: 2745503:HU724_RS25890
uniprot id: A0A9E6P976
names: Subcellular Location Annotation
messages: Cytoplasm

2745503:HU724 RS04970
gene id: 2745503:HU724_RS04970
uniprot id: A0A9E6PBH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS21990
gene id: 2745503:HU724_RS21990
uniprot id: A0A9E6TL28
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

2745503:HU724 RS21080
gene id: 2745503:HU724_RS21080
uniprot id: A0A9E6P8L0
names: Subcellular Location Annotation
messages: Cell inner membrane

2745503:HU724 RS25280
gene id: 2745503:HU724_RS25280
uniprot id: A0A9E6P926
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2745503:HU724 RS24155
gene id: 2745503:HU724_RS24155
uniprot id: A0A9E6P8K1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2745503:HU724 RS26255
gene id: 2745503:HU724_RS26255
uniprot id: A0A9E6PAA4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

2745503:HU724 RS04700
gene id: 2745503:HU724_RS04700
uniprot id: A0A9E6PBG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

2745503:HU724 RS02940
gene id: 2745503:HU724_RS02940
uniprot id: A0A9E6PAR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS19990
gene id: 2745503:HU724_RS19990
uniprot id: A0A9E6TKQ0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS05840
gene id: 2745503:HU724_RS05840
uniprot id: A0A9E6TML7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

2745503:HU724 RS23000
gene id: 2745503:HU724_RS23000
uniprot id: A0A9E6TL85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

2745503:HU724 RS20235
gene id: 2745503:HU724_RS20235
uniprot id: A0A9E6TKI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

2745503:HU724 RS25250
gene id: 2745503:HU724_RS25250
uniprot id: A0A9E6TKN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2745503:HU724 RS08190
gene id: 2745503:HU724_RS08190
uniprot id: A0A9E6TNE7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2745503:HU724 RS27410
gene id: 2745503:HU724_RS27410
uniprot id: A0A9E6TLJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS19775
gene id: 2745503:HU724_RS19775
uniprot id: A0A9E6TKF5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745503:HU724 RS26160
gene id: 2745503:HU724_RS26160
uniprot id: A0A9E6TM74
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS17495
gene id: 2745503:HU724_RS17495
uniprot id: A0A9E6P6S9
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS26945
gene id: 2745503:HU724_RS26945
uniprot id: A0A9E6PAG1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2745503:HU724 RS18015
gene id: 2745503:HU724_RS18015
uniprot id: A0A9E6TJD7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS06920
gene id: 2745503:HU724_RS06920
uniprot id: A0A9E6PDQ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

2745503:HU724 RS23245
gene id: 2745503:HU724_RS23245
uniprot id: A0A9E6TKX7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

2745503:HU724 RS00220
gene id: 2745503:HU724_RS00220
uniprot id: A0A9E6P9R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

2745503:HU724 RS06810
gene id: 2745503:HU724_RS06810
uniprot id: A0A9E6PD80
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS06270
gene id: 2745503:HU724_RS06270
uniprot id: A0A9E6PBV6
names: Subcellular Location Annotation
messages: Cytoplasm

2745503:HU724 RS23815
gene id: 2745503:HU724_RS23815
uniprot id: A0A9E6TL17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS03630
gene id: 2745503:HU724_RS03630
uniprot id: A0A9E6PBX6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

2745503:HU724 RS27175
gene id: 2745503:HU724_RS27175
uniprot id: A0A9E6TKZ8
names: Similarity
messages: Belongs to the thioredoxin family.

2745503:HU724 RS24010
gene id: 2745503:HU724_RS24010
uniprot id: A0A9E6TL10
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

2745503:HU724 RS23290
gene id: 2745503:HU724_RS23290
uniprot id: A0A9E6P8D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2745503:HU724 RS09700
gene id: 2745503:HU724_RS09700
uniprot id: A0A9E6TMQ9
names: Similarity
messages: Belongs to the peptidase S13 family.

2745503:HU724 RS25555
gene id: 2745503:HU724_RS25555
uniprot id: A0A9E6P953
names: Similarity
messages: Belongs to the TrpC family.

2745503:HU724 RS23665
gene id: 2745503:HU724_RS23665
uniprot id: A0A9E6P930
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

2745503:HU724 RS18605
gene id: 2745503:HU724_RS18605
uniprot id: A0A9E6P7T9
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

2745503:HU724 RS19480
gene id: 2745503:HU724_RS19480
uniprot id: A0A9E6P7A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

2745503:HU724 RS04840
gene id: 2745503:HU724_RS04840
uniprot id: A0A9E6TLU1
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

2745503:HU724 RS04300
gene id: 2745503:HU724_RS04300
uniprot id: A0A9E6PBR6
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS07510
gene id: 2745503:HU724_RS07510
uniprot id: A0A9E6PDE9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745503:HU724 RS27300
gene id: 2745503:HU724_RS27300
uniprot id: A0A9E6P9M0
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

2745503:HU724 RS06670
gene id: 2745503:HU724_RS06670
uniprot id: A0A9E6PCE5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

2745503:HU724 RS01795
gene id: 2745503:HU724_RS01795
uniprot id: A0A9E6PAN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS08215
gene id: 2745503:HU724_RS08215
uniprot id: A0A9E6PDM9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

2745503:HU724 RS07945
gene id: 2745503:HU724_RS07945
uniprot id: A0A9E6PD52
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS04310
gene id: 2745503:HU724_RS04310
uniprot id: A0A9E6TMM9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2745503:HU724 RS10825
gene id: 2745503:HU724_RS10825
uniprot id: A0A9E6PE63
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2745503:HU724 RS07535
gene id: 2745503:HU724_RS07535
uniprot id: A0A9E6PCY6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

2745503:HU724 RS20785
gene id: 2745503:HU724_RS20785
uniprot id: A0A9E6TL56
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2745503:HU724 RS17450
gene id: 2745503:HU724_RS17450
uniprot id: A0A9E6P696
names: Similarity
messages: Belongs to the glutamine synthetase family.

2745503:HU724 RS01950
gene id: 2745503:HU724_RS01950
uniprot id: A0A9E6PAQ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS05260
gene id: 2745503:HU724_RS05260
uniprot id: A0A9E6PCD9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

2745503:HU724 RS00955
gene id: 2745503:HU724_RS00955
uniprot id: A0A9E6TL62
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS17075
gene id: 2745503:HU724_RS17075
uniprot id: A0A9E6P730
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

2745503:HU724 RS07100
gene id: 2745503:HU724_RS07100
uniprot id: A0A9E6TM95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2.A.1.15) family.
messages: Membrane

2745503:HU724 RS24095
gene id: 2745503:HU724_RS24095
uniprot id: A0A9E6P984
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS25410
gene id: 2745503:HU724_RS25410
uniprot id: A0A9E6TM31
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS21930
gene id: 2745503:HU724_RS21930
uniprot id: A0A9E6P8T8
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS01765
gene id: 2745503:HU724_RS01765
uniprot id: A0A9E6TMR9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2745503:HU724 RS08425
gene id: 2745503:HU724_RS08425
uniprot id: A0A9E6TMI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

2745503:HU724 RS07235
gene id: 2745503:HU724_RS07235
uniprot id: A0A9E6PCL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

2745503:HU724 RS06840
gene id: 2745503:HU724_RS06840
uniprot id: A0A9E6PC22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2745503:HU724 RS25105
gene id: 2745503:HU724_RS25105
uniprot id: A0A9E6TL86
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

2745503:HU724 RS27165
gene id: 2745503:HU724_RS27165
uniprot id: A0A9E6TLW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

2745503:HU724 RS23270
gene id: 2745503:HU724_RS23270
uniprot id: A0A9E6P8Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS20915
gene id: 2745503:HU724_RS20915
uniprot id: A0A9E6P7Q6
names: Similarity
messages: Belongs to the GST superfamily.

2745503:HU724 RS20700
gene id: 2745503:HU724_RS20700
uniprot id: A0A9E6TJT8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS05645
gene id: 2745503:HU724_RS05645
uniprot id: A0A9E6PCQ2
names: Similarity
messages: Belongs to the D-mannuronate C5-epimerase family.

2745503:HU724 RS25610
gene id: 2745503:HU724_RS25610
uniprot id: A0A9E6TM38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

2745503:HU724 RS00900
gene id: 2745503:HU724_RS00900
uniprot id: A0A9E6PB21
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

2745503:HU724 RS13340
gene id: 2745503:HU724_RS13340
uniprot id: A0A9E6PED1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

2745503:HU724 RS13445
gene id: 2745503:HU724_RS13445
uniprot id: A0A9E6TPD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

2745503:HU724 RS00455
gene id: 2745503:HU724_RS00455
uniprot id: A0A9E6P9U9
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

2745503:HU724 RS10990
gene id: 2745503:HU724_RS10990
uniprot id: A0A9E6PEN9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS21755
gene id: 2745503:HU724_RS21755
uniprot id: A0A9E6TK03
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

2745503:HU724 RS06635
gene id: 2745503:HU724_RS06635
uniprot id: A0A9E6PD61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

2745503:HU724 RS08760
gene id: 2745503:HU724_RS08760
uniprot id: A0A9E6PCR3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

2745503:HU724 RS13385
gene id: 2745503:HU724_RS13385
uniprot id: A0A9E6PFP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

2745503:HU724 RS00565
gene id: 2745503:HU724_RS00565
uniprot id: A0A9E6TM19
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

2745503:HU724 RS16560
gene id: 2745503:HU724_RS16560
uniprot id: A0A9E6P5Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745503:HU724 RS21795
gene id: 2745503:HU724_RS21795
uniprot id: A0A9E6P8Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745503:HU724 RS08310
gene id: 2745503:HU724_RS08310
uniprot id: A0A9E6PDE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

2745503:HU724 RS25245
gene id: 2745503:HU724_RS25245
uniprot id: A0A9E6TLI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2745503:HU724 RS08095
gene id: 2745503:HU724_RS08095
uniprot id: A0A9E6PD71
names: Similarity
messages: Belongs to the YciI family.

2745503:HU724 RS24450
gene id: 2745503:HU724_RS24450
uniprot id: A0A9E6P936
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

2745503:HU724 RS18520
gene id: 2745503:HU724_RS18520
uniprot id: A0A9E6P7L0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS00510
gene id: 2745503:HU724_RS00510
uniprot id: A0A9E6TMI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

2745503:HU724 RS21265
gene id: 2745503:HU724_RS21265
uniprot id: A0A9E6TKI9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2745503:HU724 RS04800
gene id: 2745503:HU724_RS04800
uniprot id: A0A9E6PBW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

2745503:HU724 RS21605
gene id: 2745503:HU724_RS21605
uniprot id: A0A9E6TJZ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS26490
gene id: 2745503:HU724_RS26490
uniprot id: A0A9E6PA82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

2745503:HU724 RS25305
gene id: 2745503:HU724_RS25305
uniprot id: A0A9E6P901
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2745503:HU724 RS22050
gene id: 2745503:HU724_RS22050
uniprot id: A0A9E6P8X9
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

2745503:HU724 RS06395
gene id: 2745503:HU724_RS06395
uniprot id: A0A9E6PD34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

2745503:HU724 RS05805
gene id: 2745503:HU724_RS05805
uniprot id: A0A9E6PBQ0
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

2745503:HU724 RS26840
gene id: 2745503:HU724_RS26840
uniprot id: A0A9E6TLU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

2745503:HU724 RS07865
gene id: 2745503:HU724_RS07865
uniprot id: A0A9E6PD59
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS18000
gene id: 2745503:HU724_RS18000
uniprot id: A0A9E6P6V0
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

2745503:HU724 RS01205
gene id: 2745503:HU724_RS01205
uniprot id: A0A9E6PB61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.
messages: Catalyzes the proton-dependent transport of glutamate and aspartate.
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS09060
gene id: 2745503:HU724_RS09060
uniprot id: A0A9E6TML4
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS08470
gene id: 2745503:HU724_RS08470
uniprot id: A0A9E6PCM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

2745503:HU724 RS24900
gene id: 2745503:HU724_RS24900
uniprot id: A0A9E6P9P5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

2745503:HU724 RS08740
gene id: 2745503:HU724_RS08740
uniprot id: A0A9E6TP14
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

2745503:HU724 RS18350
gene id: 2745503:HU724_RS18350
uniprot id: A0A9E6P6L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

2745503:HU724 RS03555
gene id: 2745503:HU724_RS03555
uniprot id: A0A9E6PBS9
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

2745503:HU724 RS21295
gene id: 2745503:HU724_RS21295
uniprot id: A0A9E6P8K7
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

2745503:HU724 RS18100
gene id: 2745503:HU724_RS18100
uniprot id: A0A9E6TKM8
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS19980
gene id: 2745503:HU724_RS19980
uniprot id: A0A9E6P753
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

2745503:HU724 RS24775
gene id: 2745503:HU724_RS24775
uniprot id: A0A9E6PG78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

2745503:HU724 RS01115
gene id: 2745503:HU724_RS01115
uniprot id: A0A9E6TLS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

2745503:HU724 RS24615
gene id: 2745503:HU724_RS24615
uniprot id: A0A9E6P8R3
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS08170
gene id: 2745503:HU724_RS08170
uniprot id: A0A9E6PCI6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

2745503:HU724 RS03610
gene id: 2745503:HU724_RS03610
uniprot id: A0A9E6TMI4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

2745503:HU724 RS21705
gene id: 2745503:HU724_RS21705
uniprot id: A0A9E6P8Q6
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

2745503:HU724 RS17945
gene id: 2745503:HU724_RS17945
uniprot id: A0A9E6TK39
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS08590
gene id: 2745503:HU724_RS08590
uniprot id: A0A9E6PDS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

2745503:HU724 RS22970
gene id: 2745503:HU724_RS22970
uniprot id: A0A9E6P996
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

2745503:HU724 RS05085
gene id: 2745503:HU724_RS05085
uniprot id: A0A9E6TMG7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

2745503:HU724 RS21830
gene id: 2745503:HU724_RS21830
uniprot id: A0A9E6TKN5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

2745503:HU724 RS23565
gene id: 2745503:HU724_RS23565
uniprot id: A0A9E6TLB3
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

2745503:HU724 RS02525
gene id: 2745503:HU724_RS02525
uniprot id: A0A9E6PAN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

2745503:HU724 RS01330
gene id: 2745503:HU724_RS01330
uniprot id: A0A9E6TM67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745503:HU724 RS10215
gene id: 2745503:HU724_RS10215
uniprot id: A0A9E6PD58
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

2745503:HU724 RS21275
gene id: 2745503:HU724_RS21275
uniprot id: A0A9E6TKM2
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

2745503:HU724 RS25215
gene id: 2745503:HU724_RS25215
uniprot id: A0A9E6P9C1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2745503:HU724 RS26990
gene id: 2745503:HU724_RS26990
uniprot id: A0A9E6PA39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

2745503:HU724 RS03730
gene id: 2745503:HU724_RS03730
uniprot id: A0A9E6PC50
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2745503:HU724 RS04920
gene id: 2745503:HU724_RS04920
uniprot id: A0A9E6TLU7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

2745503:HU724 RS08185
gene id: 2745503:HU724_RS08185
uniprot id: A0A9E6PD79
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

2745503:HU724 RS26000
gene id: 2745503:HU724_RS26000
uniprot id: A0A9E6TKR6
names: Similarity
messages: Belongs to the GcvT family.

2745503:HU724 RS01085
gene id: 2745503:HU724_RS01085
uniprot id: A0A9E6PBG4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

2745503:HU724 RS01050
gene id: 2745503:HU724_RS01050
uniprot id: A0A9E6PB09
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2745503:HU724 RS02100
gene id: 2745503:HU724_RS02100
uniprot id: A0A9E6PAR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS07450
gene id: 2745503:HU724_RS07450
uniprot id: A0A9E6PCB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

2745503:HU724 RS02550
gene id: 2745503:HU724_RS02550
uniprot id: A0A9E6PC30
names: Similarity
messages: Belongs to the peptidase S41A family.

2745503:HU724 RS03125
gene id: 2745503:HU724_RS03125
uniprot id: A0A9E6TMH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

2745503:HU724 RS05200
gene id: 2745503:HU724_RS05200
uniprot id: A0A9E6PC13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

2745503:HU724 RS25270
gene id: 2745503:HU724_RS25270
uniprot id: A0A9E6P9Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

2745503:HU724 RS01100
gene id: 2745503:HU724_RS01100
uniprot id: A0A9E6TM54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

2745503:HU724 RS02635
gene id: 2745503:HU724_RS02635
uniprot id: A0A9E6PC38
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

2745503:HU724 RS04930
gene id: 2745503:HU724_RS04930
uniprot id: A0A9E6TNB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745503:HU724 RS15215
gene id: 2745503:HU724_RS15215
uniprot id: A0A9E6P5U9
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS00940
gene id: 2745503:HU724_RS00940
uniprot id: A0A9E6PAL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

2745503:HU724 RS06110
gene id: 2745503:HU724_RS06110
uniprot id: A0A9E6PBT6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745503:HU724 RS11095
gene id: 2745503:HU724_RS11095
uniprot id: A0A9E6TPD9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

2745503:HU724 RS21760
gene id: 2745503:HU724_RS21760
uniprot id: A0A9E6TKN7
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

2745503:HU724 RS26505
gene id: 2745503:HU724_RS26505
uniprot id: A0A9E6P9P4
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

2745503:HU724 RS25480
gene id: 2745503:HU724_RS25480
uniprot id: A0A9E6PA25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

2745503:HU724 RS24250
gene id: 2745503:HU724_RS24250
uniprot id: A0A9E6TKF3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

2745503:HU724 RS20395
gene id: 2745503:HU724_RS20395
uniprot id: A0A9E6TKJ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS06440
gene id: 2745503:HU724_RS06440
uniprot id: A0A9E6PCB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

2745503:HU724 RS01045
gene id: 2745503:HU724_RS01045
uniprot id: A0A9E6TMM6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2745503:HU724 RS04270
gene id: 2745503:HU724_RS04270
uniprot id: A0A9E6PBB8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS27215
gene id: 2745503:HU724_RS27215
uniprot id: A0A9E6P9X7
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

2745503:HU724 RS23025
gene id: 2745503:HU724_RS23025
uniprot id: A0A9E6P8V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS25235
gene id: 2745503:HU724_RS25235
uniprot id: A0A9E6P986
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2745503:HU724 RS00465
gene id: 2745503:HU724_RS00465
uniprot id: A0A9E6PA60
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Cytoplasm

2745503:HU724 RS27365
gene id: 2745503:HU724_RS27365
uniprot id: A0A9E6PAQ1
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

2745503:HU724 RS00635
gene id: 2745503:HU724_RS00635
uniprot id: A0A9E6PAH8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2745503:HU724 RS10185
gene id: 2745503:HU724_RS10185
uniprot id: A0A9E6TMU0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

2745503:HU724 RS25990
gene id: 2745503:HU724_RS25990
uniprot id: A0A9E6TLQ2
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

2745503:HU724 RS03625
gene id: 2745503:HU724_RS03625
uniprot id: A0A9E6TN35
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

2745503:HU724 RS22565
gene id: 2745503:HU724_RS22565
uniprot id: A0A9E6P920
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

2745503:HU724 RS26510
gene id: 2745503:HU724_RS26510
uniprot id: A0A9E6P9D5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

2745503:HU724 RS25315
gene id: 2745503:HU724_RS25315
uniprot id: A0A9E6TLL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2745503:HU724 RS04805
gene id: 2745503:HU724_RS04805
uniprot id: A0A9E6PBD6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

2745503:HU724 RS02065
gene id: 2745503:HU724_RS02065
uniprot id: A0A9E6TLY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745503:HU724 RS25880
gene id: 2745503:HU724_RS25880
uniprot id: A0A9E6PA71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

2745503:HU724 RS20885
gene id: 2745503:HU724_RS20885
uniprot id: A0A9E6P7K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

2745503:HU724 RS08745
gene id: 2745503:HU724_RS08745
uniprot id: A0A9E6PDT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS00165
gene id: 2745503:HU724_RS00165
uniprot id: A0A9E6TLZ2
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

2745503:HU724 RS03835
gene id: 2745503:HU724_RS03835
uniprot id: A0A9E6PBL7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

2745503:HU724 RS23680
gene id: 2745503:HU724_RS23680
uniprot id: A0A9E6P8H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

2745503:HU724 RS07470
gene id: 2745503:HU724_RS07470
uniprot id: A0A9E6PDX1
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

2745503:HU724 RS07180
gene id: 2745503:HU724_RS07180
uniprot id: A0A9E6TMU7
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS22005
gene id: 2745503:HU724_RS22005
uniprot id: A0A9E6TKP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

2745503:HU724 RS00990
gene id: 2745503:HU724_RS00990
uniprot id: A0A9E6PB40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

2745503:HU724 RS15690
gene id: 2745503:HU724_RS15690
uniprot id: A0A9E6TJX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745503:HU724 RS05225
gene id: 2745503:HU724_RS05225
uniprot id: A0A9E6TMV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

2745503:HU724 RS19400
gene id: 2745503:HU724_RS19400
uniprot id: A0A9E6P795
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

2745503:HU724 RS25325
gene id: 2745503:HU724_RS25325
uniprot id: A0A9E6TKN4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2745503:HU724 RS08700
gene id: 2745503:HU724_RS08700
uniprot id: A0A9E6PCT4
names: Similarity
messages: Belongs to the MlaA family.

2745503:HU724 RS20710
gene id: 2745503:HU724_RS20710
uniprot id: A0A9E6TL54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm

2745503:HU724 RS19830
gene id: 2745503:HU724_RS19830
uniprot id: A0A9E6P7C3
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

2745503:HU724 RS11745
gene id: 2745503:HU724_RS11745
uniprot id: A0A9E6PF39
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS06310
gene id: 2745503:HU724_RS06310
uniprot id: A0A9E6TNL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS24750
gene id: 2745503:HU724_RS24750
uniprot id: A0A9E6P8V9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

2745503:HU724 RS13095
gene id: 2745503:HU724_RS13095
uniprot id: A0A9E6PFE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745503:HU724 RS17525
gene id: 2745503:HU724_RS17525
uniprot id: A0A9E6P6A3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

2745503:HU724 RS06460
gene id: 2745503:HU724_RS06460
uniprot id: A0A9E6TM55
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS27450
gene id: 2745503:HU724_RS27450
uniprot id: A0A9E6P9P0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS03850
gene id: 2745503:HU724_RS03850
uniprot id: A0A9E6TLK2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

2745503:HU724 RS20055
gene id: 2745503:HU724_RS20055
uniprot id: A0A9E6P882
names: Similarity
messages: Belongs to the OsmC/Ohr family.

2745503:HU724 RS08100
gene id: 2745503:HU724_RS08100
uniprot id: A0A9E6TNE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

2745503:HU724 RS25300
gene id: 2745503:HU724_RS25300
uniprot id: A0A9E6PAC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2745503:HU724 RS08765
gene id: 2745503:HU724_RS08765
uniprot id: A0A9E6PDJ4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: The active site is a redox-active disulfide bond.

2745503:HU724 RS25310
gene id: 2745503:HU724_RS25310
uniprot id: A0A9E6P9G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2745503:HU724 RS24320
gene id: 2745503:HU724_RS24320
uniprot id: A0A9E6TL47
names: Similarity
messages: Belongs to the peptidase S16 family.

2745503:HU724 RS24525
gene id: 2745503:HU724_RS24525
uniprot id: A0A9E6P946
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS03375
gene id: 2745503:HU724_RS03375
uniprot id: A0A9E6TLH5
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

2745503:HU724 RS10140
gene id: 2745503:HU724_RS10140
uniprot id: A0A9E6PEQ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2745503:HU724 RS09595
gene id: 2745503:HU724_RS09595
uniprot id: A0A9E6PD56
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

2745503:HU724 RS24025
gene id: 2745503:HU724_RS24025
uniprot id: A0A9E6P9H4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

2745503:HU724 RS25000
gene id: 2745503:HU724_RS25000
uniprot id: A0A9E6PA89
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

2745503:HU724 RS19515
gene id: 2745503:HU724_RS19515
uniprot id: A0A9E6TJL1
names: Function
names: Similarity
names: Subunit
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).
messages: In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.

2745503:HU724 RS06450
gene id: 2745503:HU724_RS06450
uniprot id: A0A9E6TN43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2745503:HU724 RS03455
gene id: 2745503:HU724_RS03455
uniprot id: A0A9E6TM66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

2745503:HU724 RS19710
gene id: 2745503:HU724_RS19710
uniprot id: A0A9E6P7Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS27390
gene id: 2745503:HU724_RS27390
uniprot id: A0A9E6PA88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

2745503:HU724 RS02425
gene id: 2745503:HU724_RS02425
uniprot id: A0A9E6PBG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS01900
gene id: 2745503:HU724_RS01900
uniprot id: A0A9E6TMA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

2745503:HU724 RS25725
gene id: 2745503:HU724_RS25725
uniprot id: A0A9E6PAH2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

2745503:HU724 RS00915
gene id: 2745503:HU724_RS00915
uniprot id: A0A9E6PB26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

2745503:HU724 RS18435
gene id: 2745503:HU724_RS18435
uniprot id: A0A9E6P7S2
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

2745503:HU724 RS08485
gene id: 2745503:HU724_RS08485
uniprot id: A0A9E6PDC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

2745503:HU724 RS19560
gene id: 2745503:HU724_RS19560
uniprot id: A0A9E6P6W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Sulfur carrier protein which probably makes part of a sulfur-relay system.

2745503:HU724 RS00105
gene id: 2745503:HU724_RS00105
uniprot id: A0A9E6TMG4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2745503:HU724 RS22520
gene id: 2745503:HU724_RS22520
uniprot id: A0A9E6P938
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

2745503:HU724 RS26610
gene id: 2745503:HU724_RS26610
uniprot id: A0A9E6TLT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

2745503:HU724 RS20175
gene id: 2745503:HU724_RS20175
uniprot id: A0A9E6P853
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: Membrane

2745503:HU724 RS23105
gene id: 2745503:HU724_RS23105
uniprot id: A0A9E6TKW1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

2745503:HU724 RS18130
gene id: 2745503:HU724_RS18130
uniprot id: A0A9E6P6V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745503:HU724 RS18065
gene id: 2745503:HU724_RS18065
uniprot id: A0A9E6P7H6
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

2745503:HU724 RS02505
gene id: 2745503:HU724_RS02505
uniprot id: A0A9E6TMW3
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS05870
gene id: 2745503:HU724_RS05870
uniprot id: A0A9E6PCQ9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

2745503:HU724 RS25535
gene id: 2745503:HU724_RS25535
uniprot id: A0A9E6TM35
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

2745503:HU724 RS22090
gene id: 2745503:HU724_RS22090
uniprot id: A0A9E6P8H5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

2745503:HU724 RS25345
gene id: 2745503:HU724_RS25345
uniprot id: A0A9E6P9Z6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2745503:HU724 RS26835
gene id: 2745503:HU724_RS26835
uniprot id: A0A9E6PA15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

2745503:HU724 RS24890
gene id: 2745503:HU724_RS24890
uniprot id: A0A9E6P9Q4
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS15590
gene id: 2745503:HU724_RS15590
uniprot id: A0A9E6P5N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS19525
gene id: 2745503:HU724_RS19525
uniprot id: A0A9E6TKY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

2745503:HU724 RS01880
gene id: 2745503:HU724_RS01880
uniprot id: A0A9E6PAC8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

2745503:HU724 RS00640
gene id: 2745503:HU724_RS00640
uniprot id: A0A9E6TM24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS21480
gene id: 2745503:HU724_RS21480
uniprot id: A0A9E6P7S3
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

2745503:HU724 RS00235
gene id: 2745503:HU724_RS00235
uniprot id: A0A9E6PAC9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS11040
gene id: 2745503:HU724_RS11040
uniprot id: A0A9E6PDI0
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS25225
gene id: 2745503:HU724_RS25225
uniprot id: A0A9E6PAB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

2745503:HU724 RS06065
gene id: 2745503:HU724_RS06065
uniprot id: A0A9E6TMN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm
messages: Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs).

2745503:HU724 RS02570
gene id: 2745503:HU724_RS02570
uniprot id: A0A9E6TMB8
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

2745503:HU724 RS07550
gene id: 2745503:HU724_RS07550
uniprot id: A0A9E6PCT5
names: Subcellular Location Annotation
messages: Cytoplasm

2745503:HU724 RS16485
gene id: 2745503:HU724_RS16485
uniprot id: A0A9E6P6X1
names: Similarity
messages: Belongs to the IlvD/Edd family.

2745503:HU724 RS08475
gene id: 2745503:HU724_RS08475
uniprot id: A0A9E6PE78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

2745503:HU724 RS23705
gene id: 2745503:HU724_RS23705
uniprot id: A0A9E6P9R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

2745503:HU724 RS23110
gene id: 2745503:HU724_RS23110
uniprot id: A0A9E6TLP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

2745503:HU724 RS03165
gene id: 2745503:HU724_RS03165
uniprot id: A0A9E6PAX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS05205
gene id: 2745503:HU724_RS05205
uniprot id: A0A9E6PBJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.

2745503:HU724 RS26015
gene id: 2745503:HU724_RS26015
uniprot id: A0A9E6PA44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

2745503:HU724 RS27420
gene id: 2745503:HU724_RS27420
uniprot id: A0A9E6PAL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

2745503:HU724 RS21270
gene id: 2745503:HU724_RS21270
uniprot id: A0A9E6TJX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

2745503:HU724 RS23490
gene id: 2745503:HU724_RS23490
uniprot id: A0A9E6TLA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

2745503:HU724 RS21190
gene id: 2745503:HU724_RS21190
uniprot id: A0A9E6TKI4
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS24275
gene id: 2745503:HU724_RS24275
uniprot id: A0A9E6P9G2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2745503:HU724 RS18020
gene id: 2745503:HU724_RS18020
uniprot id: A0A9E6TK44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

2745503:HU724 RS00240
gene id: 2745503:HU724_RS00240
uniprot id: A0A9E6TLZ7
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

2745503:HU724 RS00540
gene id: 2745503:HU724_RS00540
uniprot id: A0A9E6PA70
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

2745503:HU724 RS03615
gene id: 2745503:HU724_RS03615
uniprot id: A0A9E6TLJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

2745503:HU724 RS26620
gene id: 2745503:HU724_RS26620
uniprot id: A0A9E6TKV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

2745503:HU724 RS24270
gene id: 2745503:HU724_RS24270
uniprot id: A0A9E6P9K6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2745503:HU724 RS04570
gene id: 2745503:HU724_RS04570
uniprot id: A0A9E6PBN2
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

2745503:HU724 RS24870
gene id: 2745503:HU724_RS24870
uniprot id: A0A9E6TLG7
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.

2745503:HU724 RS02780
gene id: 2745503:HU724_RS02780
uniprot id: A0A9E6PB00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

2745503:HU724 RS00945
gene id: 2745503:HU724_RS00945
uniprot id: A0A9E6TM44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2745503:HU724 RS25335
gene id: 2745503:HU724_RS25335
uniprot id: A0A9E6TM26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2745503:HU724 RS01875
gene id: 2745503:HU724_RS01875
uniprot id: A0A9E6PAP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

2745503:HU724 RS02225
gene id: 2745503:HU724_RS02225
uniprot id: A0A9E6TMA0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2745503:HU724 RS07035
gene id: 2745503:HU724_RS07035
uniprot id: A0A9E6PD98
names: Similarity
messages: Belongs to the leucine-binding protein family.

2745503:HU724 RS24540
gene id: 2745503:HU724_RS24540
uniprot id: A0A9E6P8Q3
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

2745503:HU724 RS12210
gene id: 2745503:HU724_RS12210
uniprot id: A0A9E6TPL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

2745503:HU724 RS23905
gene id: 2745503:HU724_RS23905
uniprot id: A0A9E6P8H0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

2745503:HU724 RS01005
gene id: 2745503:HU724_RS01005
uniprot id: A0A9E6PA17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

2745503:HU724 RS22440
gene id: 2745503:HU724_RS22440
uniprot id: A0A9E6P7U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

2745503:HU724 RS26520
gene id: 2745503:HU724_RS26520
uniprot id: A0A9E6P9M6
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS06400
gene id: 2745503:HU724_RS06400
uniprot id: A0A9E6PCP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

2745503:HU724 RS19295
gene id: 2745503:HU724_RS19295
uniprot id: A0A9E6TKX8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

2745503:HU724 RS07680
gene id: 2745503:HU724_RS07680
uniprot id: A0A9E6PD11
names: Similarity
messages: Belongs to the UPF0260 family.

2745503:HU724 RS20005
gene id: 2745503:HU724_RS20005
uniprot id: A0A9E6TKH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

2745503:HU724 RS08730
gene id: 2745503:HU724_RS08730
uniprot id: A0A9E6TMJ8
names: Similarity
messages: Belongs to the citrate synthase family.

2745503:HU724 RS21915
gene id: 2745503:HU724_RS21915
uniprot id: A0A9E6TKP5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

2745503:HU724 RS09190
gene id: 2745503:HU724_RS09190
uniprot id: A0A9E6PEE4
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

2745503:HU724 RS10765
gene id: 2745503:HU724_RS10765
uniprot id: A0A9E6TMX2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS00530
gene id: 2745503:HU724_RS00530
uniprot id: A0A9E6P9V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

2745503:HU724 RS08420
gene id: 2745503:HU724_RS08420
uniprot id: A0A9E6TNE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

2745503:HU724 RS03415
gene id: 2745503:HU724_RS03415
uniprot id: A0A9E6PB88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

2745503:HU724 RS04705
gene id: 2745503:HU724_RS04705
uniprot id: A0A9E6PCH5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

2745503:HU724 RS26865
gene id: 2745503:HU724_RS26865
uniprot id: A0A9E6PAF5
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

2745503:HU724 RS10830
gene id: 2745503:HU724_RS10830
uniprot id: A0A9E6PEM3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2745503:HU724 RS08920
gene id: 2745503:HU724_RS08920
uniprot id: A0A9E6PDG4
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

2745503:HU724 RS10285
gene id: 2745503:HU724_RS10285
uniprot id: A0A9E6PED6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

2745503:HU724 RS26815
gene id: 2745503:HU724_RS26815
uniprot id: A0A9E6P9T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

2745503:HU724 RS04925
gene id: 2745503:HU724_RS04925
uniprot id: A0A9E6TMF7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2745503:HU724 RS12995
gene id: 2745503:HU724_RS12995
uniprot id: A0A9E6PEV9
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

2745503:HU724 RS20135
gene id: 2745503:HU724_RS20135
uniprot id: A0A9E6P784
names: Similarity
messages: Belongs to the YkuD family.

2745503:HU724 RS05315
gene id: 2745503:HU724_RS05315
uniprot id: A0A9E6TMI6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2745503:HU724 RS25770
gene id: 2745503:HU724_RS25770
uniprot id: A0A9E6TPH3
names: Function
names: Similarity
messages: Belongs to the PqqA family.
messages: Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.

2745503:HU724 RS20370
gene id: 2745503:HU724_RS20370
uniprot id: A0A9E6P7A1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

2745503:HU724 RS25275
gene id: 2745503:HU724_RS25275
uniprot id: A0A9E6P9T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2745503:HU724 RS25220
gene id: 2745503:HU724_RS25220
uniprot id: A0A9E6P8Z4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2745503:HU724 RS02005
gene id: 2745503:HU724_RS02005
uniprot id: A0A9E6PBG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

2745503:HU724 RS02735
gene id: 2745503:HU724_RS02735
uniprot id: A0A9E6TMC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

2745503:HU724 RS02595
gene id: 2745503:HU724_RS02595
uniprot id: A0A9E6PBK7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

2745503:HU724 RS14195
gene id: 2745503:HU724_RS14195
uniprot id: A0A9E6TJ51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

2745503:HU724 RS10085
gene id: 2745503:HU724_RS10085
uniprot id: A0A9E6TMT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

2745503:HU724 RS17465
gene id: 2745503:HU724_RS17465
uniprot id: A0A9E6P6P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2745503:HU724 RS05245
gene id: 2745503:HU724_RS05245
uniprot id: A0A9E6TND6
names: Similarity
messages: Belongs to the BolA/IbaG family.

2745503:HU724 RS02145
gene id: 2745503:HU724_RS02145
uniprot id: A0A9E6TM94
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

2745503:HU724 RS16545
gene id: 2745503:HU724_RS16545
uniprot id: A0A9E6P6Z7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

2745503:HU724 RS24755
gene id: 2745503:HU724_RS24755
uniprot id: A0A9E6P9S8
names: Similarity
messages: Belongs to the UPF0250 family.

2745503:HU724 RS02435
gene id: 2745503:HU724_RS02435
uniprot id: A0A9E6PBD9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

2745503:HU724 RS11320
gene id: 2745503:HU724_RS11320
uniprot id: A0A9E6PF45
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS06785
gene id: 2745503:HU724_RS06785
uniprot id: A0A9E6TM75
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS24280
gene id: 2745503:HU724_RS24280
uniprot id: A0A9E6P8P7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

2745503:HU724 RS12855
gene id: 2745503:HU724_RS12855
uniprot id: A0A9E6PFB9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS18485
gene id: 2745503:HU724_RS18485
uniprot id: A0A9E6TKE9
names: Similarity
messages: Belongs to the peptidase S11 family.

2745503:HU724 RS11085
gene id: 2745503:HU724_RS11085
uniprot id: A0A9E6TMZ4
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

2745503:HU724 RS07030
gene id: 2745503:HU724_RS07030
uniprot id: A0A9E6TNQ8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS04495
gene id: 2745503:HU724_RS04495
uniprot id: A0A9E6TPC7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS06415
gene id: 2745503:HU724_RS06415
uniprot id: A0A9E6PF62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

2745503:HU724 RS00120
gene id: 2745503:HU724_RS00120
uniprot id: A0A9E6PAM4
names: Similarity
messages: Belongs to the UPF0758 family.

2745503:HU724 RS07570
gene id: 2745503:HU724_RS07570
uniprot id: A0A9E6TMC3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

2745503:HU724 RS27195
gene id: 2745503:HU724_RS27195
uniprot id: A0A9E6PAM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS18755
gene id: 2745503:HU724_RS18755
uniprot id: A0A9E6P7P0
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

2745503:HU724 RS24845
gene id: 2745503:HU724_RS24845
uniprot id: A0A9E6P8U4
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS06720
gene id: 2745503:HU724_RS06720
uniprot id: A0A9E6PCR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

2745503:HU724 RS21470
gene id: 2745503:HU724_RS21470
uniprot id: A0A9E6P8M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2745503:HU724 RS25020
gene id: 2745503:HU724_RS25020
uniprot id: A0A9E6TLH4
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

2745503:HU724 RS26025
gene id: 2745503:HU724_RS26025
uniprot id: A0A9E6PA22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
messages: Homotetramer.

2745503:HU724 RS23495
gene id: 2745503:HU724_RS23495
uniprot id: A0A9E6TL00
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

2745503:HU724 RS26795
gene id: 2745503:HU724_RS26795
uniprot id: A0A9E6PAH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS07650
gene id: 2745503:HU724_RS07650
uniprot id: A0A9E6TN91
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS00485
gene id: 2745503:HU724_RS00485
uniprot id: A0A9E6PAF8
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

2745503:HU724 RS03965
gene id: 2745503:HU724_RS03965
uniprot id: A0A9E6PB79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS26345
gene id: 2745503:HU724_RS26345
uniprot id: A0A9E6PAD1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

2745503:HU724 RS01635
gene id: 2745503:HU724_RS01635
uniprot id: A0A9E6PBB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

2745503:HU724 RS17620
gene id: 2745503:HU724_RS17620
uniprot id: A0A9E6P6R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

2745503:HU724 RS26615
gene id: 2745503:HU724_RS26615
uniprot id: A0A9E6TLQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

2745503:HU724 RS01395
gene id: 2745503:HU724_RS01395
uniprot id: A0A9E6PAH0
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS05335
gene id: 2745503:HU724_RS05335
uniprot id: A0A9E6PCE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

2745503:HU724 RS05930
gene id: 2745503:HU724_RS05930
uniprot id: A0A9E6PCY8
names: Similarity
messages: Belongs to the YkuD family.

2745503:HU724 RS05090
gene id: 2745503:HU724_RS05090
uniprot id: A0A9E6TNC7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

2745503:HU724 RS20045
gene id: 2745503:HU724_RS20045
uniprot id: A0A9E6P7G4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS21955
gene id: 2745503:HU724_RS21955
uniprot id: A0A9E6P876
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

2745503:HU724 RS10230
gene id: 2745503:HU724_RS10230
uniprot id: A0A9E6PDD8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

2745503:HU724 RS25085
gene id: 2745503:HU724_RS25085
uniprot id: A0A9E6P968
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

2745503:HU724 RS25785
gene id: 2745503:HU724_RS25785
uniprot id: A0A9E6PA45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PqqD family.
messages: Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
messages: Monomer. Interacts with PqqE.

2745503:HU724 RS24260
gene id: 2745503:HU724_RS24260
uniprot id: A0A9E6TLW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS20805
gene id: 2745503:HU724_RS20805
uniprot id: A0A9E6P8D3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2745503:HU724 RS25830
gene id: 2745503:HU724_RS25830
uniprot id: A0A9E6P9M2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2745503:HU724 RS07530
gene id: 2745503:HU724_RS07530
uniprot id: A0A9E6PD57
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

2745503:HU724 RS26320
gene id: 2745503:HU724_RS26320
uniprot id: A0A9E6TM83
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS25045
gene id: 2745503:HU724_RS25045
uniprot id: A0A9E6P9V8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

2745503:HU724 RS27380
gene id: 2745503:HU724_RS27380
uniprot id: A0A9E6PB31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

2745503:HU724 RS10815
gene id: 2745503:HU724_RS10815
uniprot id: A0A9E6PEY7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

2745503:HU724 RS19875
gene id: 2745503:HU724_RS19875
uniprot id: A0A9E6P821
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

2745503:HU724 RS06390
gene id: 2745503:HU724_RS06390
uniprot id: A0A9E6PD23
names: Similarity
messages: Belongs to the Skp family.

2745503:HU724 RS03540
gene id: 2745503:HU724_RS03540
uniprot id: A0A9E6TN32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

2745503:HU724 RS08850
gene id: 2745503:HU724_RS08850
uniprot id: A0A9E6PCV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

2745503:HU724 RS18160
gene id: 2745503:HU724_RS18160
uniprot id: A0A9E6TJZ6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

2745503:HU724 RS05690
gene id: 2745503:HU724_RS05690
uniprot id: A0A9E6TMK5
names: Similarity
messages: Belongs to the PhoH family.

2745503:HU724 RS05470
gene id: 2745503:HU724_RS05470
uniprot id: A0A9E6TNF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS23710
gene id: 2745503:HU724_RS23710
uniprot id: A0A9E6P8D2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

2745503:HU724 RS24760
gene id: 2745503:HU724_RS24760
uniprot id: A0A9E6P978
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

2745503:HU724 RS19425
gene id: 2745503:HU724_RS19425
uniprot id: A0A9E6TKK8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

2745503:HU724 RS08750
gene id: 2745503:HU724_RS08750
uniprot id: A0A9E6PDZ6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

2745503:HU724 RS01985
gene id: 2745503:HU724_RS01985
uniprot id: A0A9E6TLA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

2745503:HU724 RS23895
gene id: 2745503:HU724_RS23895
uniprot id: A0A9E6P8H1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2745503:HU724 RS26535
gene id: 2745503:HU724_RS26535
uniprot id: A0A9E6TLQ6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

2745503:HU724 RS08670
gene id: 2745503:HU724_RS08670
uniprot id: A0A9E6PDY7
names: Similarity
messages: Belongs to the TPP enzyme family.

2745503:HU724 RS03430
gene id: 2745503:HU724_RS03430
uniprot id: A0A9E6PB56
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

2745503:HU724 RS02530
gene id: 2745503:HU724_RS02530
uniprot id: A0A9E6PBJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

2745503:HU724 RS05525
gene id: 2745503:HU724_RS05525
uniprot id: A0A9E6TMX8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2745503:HU724 RS21880
gene id: 2745503:HU724_RS21880
uniprot id: A0A9E6P7N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

2745503:HU724 RS06715
gene id: 2745503:HU724_RS06715
uniprot id: A0A9E6PD70
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

2745503:HU724 RS27445
gene id: 2745503:HU724_RS27445
uniprot id: A0A9E6PA08
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2745503:HU724 RS24495
gene id: 2745503:HU724_RS24495
uniprot id: A0A9E6TLX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

2745503:HU724 RS10260
gene id: 2745503:HU724_RS10260
uniprot id: A0A9E6TNQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

2745503:HU724 RS18645
gene id: 2745503:HU724_RS18645
uniprot id: A0A9E6TJG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS04815
gene id: 2745503:HU724_RS04815
uniprot id: A0A9E6PBQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

2745503:HU724 RS26060
gene id: 2745503:HU724_RS26060
uniprot id: A0A9E6P9Q1
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

2745503:HU724 RS04680
gene id: 2745503:HU724_RS04680
uniprot id: A0A9E6TNA4
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

2745503:HU724 RS08600
gene id: 2745503:HU724_RS08600
uniprot id: A0A9E6PDB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

2745503:HU724 RS24265
gene id: 2745503:HU724_RS24265
uniprot id: A0A9E6P9H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

2745503:HU724 RS26500
gene id: 2745503:HU724_RS26500
uniprot id: A0A9E6PAE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

2745503:HU724 RS25290
gene id: 2745503:HU724_RS25290
uniprot id: A0A9E6P9C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2745503:HU724 RS19530
gene id: 2745503:HU724_RS19530
uniprot id: A0A9E6P7N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

2745503:HU724 RS24060
gene id: 2745503:HU724_RS24060
uniprot id: A0A9E6P8J0
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

2745503:HU724 RS09625
gene id: 2745503:HU724_RS09625
uniprot id: A0A9E6TMQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

2745503:HU724 RS15555
gene id: 2745503:HU724_RS15555
uniprot id: A0A9E6P5Z4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2745503:HU724 RS25385
gene id: 2745503:HU724_RS25385
uniprot id: A0A9E6P9H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2745503:HU724 RS03270
gene id: 2745503:HU724_RS03270
uniprot id: A0A9E6PB35
names: Similarity
messages: Belongs to the NodU/CmcH family.

2745503:HU724 RS00520
gene id: 2745503:HU724_RS00520
uniprot id: A0A9E6PAX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS25365
gene id: 2745503:HU724_RS25365
uniprot id: A0A9E6P9D1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2745503:HU724 RS08010
gene id: 2745503:HU724_RS08010
uniprot id: A0A9E6PE20
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

2745503:HU724 RS11310
gene id: 2745503:HU724_RS11310
uniprot id: A0A9E6PEA4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

2745503:HU724 RS02355
gene id: 2745503:HU724_RS02355
uniprot id: A0A9E6PBI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

2745503:HU724 RS25800
gene id: 2745503:HU724_RS25800
uniprot id: A0A9E6P980
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

2745503:HU724 RS03565
gene id: 2745503:HU724_RS03565
uniprot id: A0A9E6PC28
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

2745503:HU724 RS02510
gene id: 2745503:HU724_RS02510
uniprot id: A0A9E6PBJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

2745503:HU724 RS07850
gene id: 2745503:HU724_RS07850
uniprot id: A0A9E6PD20
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS22980
gene id: 2745503:HU724_RS22980
uniprot id: A0A9E6P847
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

2745503:HU724 RS24765
gene id: 2745503:HU724_RS24765
uniprot id: A0A9E6P8T4
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

2745503:HU724 RS04010
gene id: 2745503:HU724_RS04010
uniprot id: A0A9E6TLL3
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

2745503:HU724 RS06285
gene id: 2745503:HU724_RS06285
uniprot id: A0A9E6PCH0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

2745503:HU724 RS20565
gene id: 2745503:HU724_RS20565
uniprot id: A0A9E6P899
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2745503:HU724 RS05055
gene id: 2745503:HU724_RS05055
uniprot id: A0A9E6PBT8
names: Similarity
messages: Belongs to the UxaA family.

2745503:HU724 RS06485
gene id: 2745503:HU724_RS06485
uniprot id: A0A9E6PCQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

2745503:HU724 RS19350
gene id: 2745503:HU724_RS19350
uniprot id: A0A9E6TKK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

2745503:HU724 RS07925
gene id: 2745503:HU724_RS07925
uniprot id: A0A9E6PD27
names: Similarity
messages: Belongs to the CvfB family.

2745503:HU724 RS00110
gene id: 2745503:HU724_RS00110
uniprot id: A0A9E6PAN8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2745503:HU724 RS03425
gene id: 2745503:HU724_RS03425
uniprot id: A0A9E6PCD8
names: Similarity
messages: Belongs to the Smp family.

2745503:HU724 RS03570
gene id: 2745503:HU724_RS03570
uniprot id: A0A9E6PBD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

2745503:HU724 RS05460
gene id: 2745503:HU724_RS05460
uniprot id: A0A9E6TLY6
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

2745503:HU724 RS17975
gene id: 2745503:HU724_RS17975
uniprot id: A0A9E6P7L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

2745503:HU724 RS17145
gene id: 2745503:HU724_RS17145
uniprot id: A0A9E6P695
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

2745503:HU724 RS20905
gene id: 2745503:HU724_RS20905
uniprot id: A0A9E6P8I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS22645
gene id: 2745503:HU724_RS22645
uniprot id: A0A9E6P919
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS27170
gene id: 2745503:HU724_RS27170
uniprot id: A0A9E6TLT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

2745503:HU724 RS14775
gene id: 2745503:HU724_RS14775
uniprot id: A0A9E6P5D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

2745503:HU724 RS21995
gene id: 2745503:HU724_RS21995
uniprot id: A0A9E6TKP3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

2745503:HU724 RS13260
gene id: 2745503:HU724_RS13260
uniprot id: A0A9E6PEC2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane
messages: The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains.

2745503:HU724 RS05845
gene id: 2745503:HU724_RS05845
uniprot id: A0A9E6TNH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

2745503:HU724 RS18090
gene id: 2745503:HU724_RS18090
uniprot id: A0A9E6TJD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2745503:HU724 RS04790
gene id: 2745503:HU724_RS04790
uniprot id: A0A9E6PBH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

2745503:HU724 RS02105
gene id: 2745503:HU724_RS02105
uniprot id: A0A9E6PAG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS15000
gene id: 2745503:HU724_RS15000
uniprot id: A0A9E6P5E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 4-oxalocrotonate tautomerase family.
messages: Catalyzes the ketonization of 2-hydroxymuconate stereoselectively to yield 2-oxo-3-hexenedioate.
messages: Homohexamer.

2745503:HU724 RS22640
gene id: 2745503:HU724_RS22640
uniprot id: A0A9E6P929
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2745503:HU724 RS21825
gene id: 2745503:HU724_RS21825
uniprot id: A0A9E6TL20
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

2745503:HU724 RS01295
gene id: 2745503:HU724_RS01295
uniprot id: A0A9E6PB81
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

2745503:HU724 RS21980
gene id: 2745503:HU724_RS21980
uniprot id: A0A9E6P7R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2745503:HU724 RS22910
gene id: 2745503:HU724_RS22910
uniprot id: A0A9E6P9G3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

2745503:HU724 RS00195
gene id: 2745503:HU724_RS00195
uniprot id: A0A9E6PAU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2745503:HU724 RS02415
gene id: 2745503:HU724_RS02415
uniprot id: A0A9E6TM00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2745503:HU724 RS26400
gene id: 2745503:HU724_RS26400
uniprot id: A0A9E6TM88
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS13680
gene id: 2745503:HU724_RS13680
uniprot id: A0A9E6P526
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

2745503:HU724 RS20520
gene id: 2745503:HU724_RS20520
uniprot id: A0A9E6P8E6
names: Similarity
messages: Belongs to the UPF0270 family.

2745503:HU724 RS26280
gene id: 2745503:HU724_RS26280
uniprot id: A0A9E6P9B6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

2745503:HU724 RS20790
gene id: 2745503:HU724_RS20790
uniprot id: A0A9E6P832
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

2745503:HU724 RS07160
gene id: 2745503:HU724_RS07160
uniprot id: A0A9E6PCW5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2745503:HU724 RS23890
gene id: 2745503:HU724_RS23890
uniprot id: A0A9E6P8W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

2745503:HU724 RS20545
gene id: 2745503:HU724_RS20545
uniprot id: A0A9E6TJS8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2745503:HU724 RS06195
gene id: 2745503:HU724_RS06195
uniprot id: A0A9E6PDH9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2745503:HU724 RS06845
gene id: 2745503:HU724_RS06845
uniprot id: A0A9E6PDP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2745503:HU724 RS01715
gene id: 2745503:HU724_RS01715
uniprot id: A0A9E6PAM3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS00555
gene id: 2745503:HU724_RS00555
uniprot id: A0A9E6PA62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2745503:HU724 RS07970
gene id: 2745503:HU724_RS07970
uniprot id: A0A9E6TNW6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2745503:HU724 RS05695
gene id: 2745503:HU724_RS05695
uniprot id: A0A9E6TNG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

2745503:HU724 RS25330
gene id: 2745503:HU724_RS25330
uniprot id: A0A9E6TL96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2745503:HU724 RS26550
gene id: 2745503:HU724_RS26550
uniprot id: A0A9E6TM98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

2745503:HU724 RS23240
gene id: 2745503:HU724_RS23240
uniprot id: A0A9E6TL95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2745503:HU724 RS25780
gene id: 2745503:HU724_RS25780
uniprot id: A0A9E6PA14
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

2745503:HU724 RS07980
gene id: 2745503:HU724_RS07980
uniprot id: A0A9E6PDR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

2745503:HU724 RS01305
gene id: 2745503:HU724_RS01305
uniprot id: A0A9E6PA58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS26180
gene id: 2745503:HU724_RS26180
uniprot id: A0A9E6P9C0
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS02495
gene id: 2745503:HU724_RS02495
uniprot id: A0A9E6TLD2
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

2745503:HU724 RS24680
gene id: 2745503:HU724_RS24680
uniprot id: A0A9E6P961
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

2745503:HU724 RS25495
gene id: 2745503:HU724_RS25495
uniprot id: A0A9E6P923
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

2745503:HU724 RS09750
gene id: 2745503:HU724_RS09750
uniprot id: A0A9E6PEJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

2745503:HU724 RS21250
gene id: 2745503:HU724_RS21250
uniprot id: A0A9E6P7I7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

2745503:HU724 RS23230
gene id: 2745503:HU724_RS23230
uniprot id: A0A9E6P879
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

2745503:HU724 RS00160
gene id: 2745503:HU724_RS00160
uniprot id: A0A9E6PAB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

2745503:HU724 RS19440
gene id: 2745503:HU724_RS19440
uniprot id: A0A9E6TKD5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

2745503:HU724 RS25130
gene id: 2745503:HU724_RS25130
uniprot id: A0A9E6P906
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsB sub-subfamily.
messages: Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane

2745503:HU724 RS06445
gene id: 2745503:HU724_RS06445
uniprot id: A0A9E6PCJ2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

2745503:HU724 RS00180
gene id: 2745503:HU724_RS00180
uniprot id: A0A9E6TLL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

2745503:HU724 RS04665
gene id: 2745503:HU724_RS04665
uniprot id: A0A9E6TMQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2745503:HU724 RS10275
gene id: 2745503:HU724_RS10275
uniprot id: A0A9E6TP98
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS17955
gene id: 2745503:HU724_RS17955
uniprot id: A0A9E6P725
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

2745503:HU724 RS22630
gene id: 2745503:HU724_RS22630
uniprot id: A0A9E6TLI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2745503:HU724 RS17675
gene id: 2745503:HU724_RS17675
uniprot id: A0A9E6P6Q6
names: Subcellular Location Annotation
messages: Membrane

2745503:HU724 RS08875
gene id: 2745503:HU724_RS08875
uniprot id: A0A9E6TNH2
names: Similarity
messages: Belongs to the peptidase C40 family.