273121:WS RS04780
gene id: 273121:WS_RS04780
uniprot id: Q7M9D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

273121:WS RS04140
gene id: 273121:WS_RS04140
uniprot id: Q7M9J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

273121:WS RS07700
gene id: 273121:WS_RS07700
uniprot id: Q7M8J0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

273121:WS RS05280
gene id: 273121:WS_RS05280
uniprot id: Q7M993
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

273121:WS RS03425
gene id: 273121:WS_RS03425
uniprot id: Q7M9S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

273121:WS RS02995
gene id: 273121:WS_RS02995
uniprot id: Q7M9X1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

273121:WS RS00490
gene id: 273121:WS_RS00490
uniprot id: Q7MAQ0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

273121:WS RS02035
gene id: 273121:WS_RS02035
uniprot id: Q7MSI3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

273121:WS RS05930
gene id: 273121:WS_RS05930
uniprot id: Q7M928
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

273121:WS RS05145
gene id: 273121:WS_RS05145
uniprot id: Q7M9A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.

273121:WS RS02485
gene id: 273121:WS_RS02485
uniprot id: Q7MA28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

273121:WS RS02990
gene id: 273121:WS_RS02990
uniprot id: Q7M9X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

273121:WS RS00705
gene id: 273121:WS_RS00705
uniprot id: Q7MAM8
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS10390
gene id: 273121:WS_RS10390
uniprot id: Q7M7M7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

273121:WS RS04030
gene id: 273121:WS_RS04030
uniprot id: Q7M9L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

273121:WS RS09805
gene id: 273121:WS_RS09805
uniprot id: Q7M7U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

273121:WS RS02520
gene id: 273121:WS_RS02520
uniprot id: Q7MA22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

273121:WS RS01520
gene id: 273121:WS_RS01520
uniprot id: Q7MAE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

273121:WS RS07620
gene id: 273121:WS_RS07620
uniprot id: Q7MR70
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

273121:WS RS00360
gene id: 273121:WS_RS00360
uniprot id: Q7MAR6
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

273121:WS RS09030
gene id: 273121:WS_RS09030
uniprot id: Q7M826
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 2Fe-2S cluster.
messages: Binds 2 [4Fe-4S] cluster.
messages: Cell membrane
messages: Iron-sulfur subunit of 8-methylmenaquinol:fumarate reductase (MFR), that catalyzes the reduction of fumarate using 8-methylmenaquinol-6 as electron donor. The complex shows no succinate oxidation activity. Is involved in anaerobic metabolism.
messages: Periplasm
messages: The MFR complex is composed of three subunits: a flavoprotein (SdhA), an iron-sulfur protein (SdhB), and one hydrophobic anchor protein (SdhE).

273121:WS RS01895
gene id: 273121:WS_RS01895
uniprot id: Q7MA98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

273121:WS RS01825
gene id: 273121:WS_RS01825
uniprot id: Q7MAA7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273121:WS RS00945
gene id: 273121:WS_RS00945
uniprot id: Q7MAK6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

273121:WS RS02170
gene id: 273121:WS_RS02170
uniprot id: Q7MA68
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

273121:WS RS04675
gene id: 273121:WS_RS04675
uniprot id: Q7M9F2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273121:WS RS09320
gene id: 273121:WS_RS09320
uniprot id: Q7MQV3
names: Similarity
messages: Belongs to the SUI1 family.

273121:WS RS04020
gene id: 273121:WS_RS04020
uniprot id: Q7M9L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

273121:WS RS10090
gene id: 273121:WS_RS10090
uniprot id: Q7M7Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

273121:WS RS05840
gene id: 273121:WS_RS05840
uniprot id: Q7M936
names: Cofactor
names: Function
names: Similarity
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

273121:WS RS05240
gene id: 273121:WS_RS05240
uniprot id: Q7M994
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

273121:WS RS03800
gene id: 273121:WS_RS03800
uniprot id: Q7M9N6
names: Similarity
messages: Belongs to the HupF/HypC family.

273121:WS RS03795
gene id: 273121:WS_RS03795
uniprot id: Q7M9N7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

273121:WS RS00715
gene id: 273121:WS_RS00715
uniprot id: Q7MAM6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

273121:WS RS00805
gene id: 273121:WS_RS00805
uniprot id: Q7MAL8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

273121:WS RS02340
gene id: 273121:WS_RS02340
uniprot id: Q7MA51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

273121:WS RS06230
gene id: 273121:WS_RS06230
uniprot id: Q7M8Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

273121:WS RS09865
gene id: 273121:WS_RS09865
uniprot id: Q7MQQ7
names: Similarity
messages: Belongs to the MotB family.

273121:WS RS06270
gene id: 273121:WS_RS06270
uniprot id: Q7M8Y6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

273121:WS RS00010
gene id: 273121:WS_RS00010
uniprot id: Q7MAV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

273121:WS RS08880
gene id: 273121:WS_RS08880
uniprot id: Q7M846
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

273121:WS RS04275
gene id: 273121:WS_RS04275
uniprot id: Q7MS06
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS03295
gene id: 273121:WS_RS03295
uniprot id: Q7MS81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

273121:WS RS07470
gene id: 273121:WS_RS07470
uniprot id: Q7MBG5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

273121:WS RS04960
gene id: 273121:WS_RS04960
uniprot id: Q7M9C0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Cell inner membrane
messages: Homopentamer. In the absence of Mg(2+), interactions between subunits are weakened, and dimers, trimers and tetramers can be observed in vitro (By similarity).
messages: Mediates influx of magnesium ions (By similarity). Alternates between open and closed states. Activated by low cytoplasmic Mg(2+) levels. Inactive when cytoplasmic Mg(2+) levels are high (By similarity).
messages: The central ion permeation pathway is formed by the first transmembrane domain from each of the five subunits. Mg(2+) binding strengthens interactions between subunits and leads to the formation of a symmetrical homopentamer surrounding a closed ion permeation pathway. Low Mg(2+) concentrations trigger both a conformation change within each subunit and a loosening of the interactions between subunits. This results in an open ion conduction pathway. In addition, this results in a less symmetrical shape of the whole complex.

273121:WS RS10150
gene id: 273121:WS_RS10150
uniprot id: Q7M7Q1
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS04235
gene id: 273121:WS_RS04235
uniprot id: Q7MS12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

273121:WS RS05385
gene id: 273121:WS_RS05385
uniprot id: Q7M981
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

273121:WS RS03920
gene id: 273121:WS_RS03920
uniprot id: Q7M9M4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

273121:WS RS03830
gene id: 273121:WS_RS03830
uniprot id: Q7M9N3
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

273121:WS RS07025
gene id: 273121:WS_RS07025
uniprot id: Q7M8R2
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

273121:WS RS01470
gene id: 273121:WS_RS01470
uniprot id: Q7MAE7
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

273121:WS RS10460
gene id: 273121:WS_RS10460
uniprot id: Q7M7L6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

273121:WS RS02535
gene id: 273121:WS_RS02535
uniprot id: Q7MA19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

273121:WS RS08040
gene id: 273121:WS_RS08040
uniprot id: Q7M8E2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

273121:WS RS00500
gene id: 273121:WS_RS00500
uniprot id: Q7MAP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

273121:WS RS03900
gene id: 273121:WS_RS03900
uniprot id: Q7M9M7
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

273121:WS RS08985
gene id: 273121:WS_RS08985
uniprot id: Q7M831
names: Similarity
messages: Belongs to the TrpC family.

273121:WS RS11260
gene id: 273121:WS_RS11260
uniprot id: Q7M7S5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

273121:WS RS06890
gene id: 273121:WS_RS06890
uniprot id: Q7MRD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

273121:WS RS02570
gene id: 273121:WS_RS02570
uniprot id: Q7MSF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

273121:WS RS08430
gene id: 273121:WS_RS08430
uniprot id: Q7M899
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS09450
gene id: 273121:WS_RS09450
uniprot id: Q7M7X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

273121:WS RS04215
gene id: 273121:WS_RS04215
uniprot id: Q7MS14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

273121:WS RS10225
gene id: 273121:WS_RS10225
uniprot id: Q7M7P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

273121:WS RS02145
gene id: 273121:WS_RS02145
uniprot id: Q7MA71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

273121:WS RS09395
gene id: 273121:WS_RS09395
uniprot id: Q7M7Y8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

273121:WS RS06050
gene id: 273121:WS_RS06050
uniprot id: Q7M918
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS04680
gene id: 273121:WS_RS04680
uniprot id: Q7M9F1
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

273121:WS RS00855
gene id: 273121:WS_RS00855
uniprot id: Q7MAL2
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

273121:WS RS10160
gene id: 273121:WS_RS10160
uniprot id: Q7MQN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

273121:WS RS08560
gene id: 273121:WS_RS08560
uniprot id: Q7M882
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

273121:WS RS07550
gene id: 273121:WS_RS07550
uniprot id: Q7M8K5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

273121:WS RS06110
gene id: 273121:WS_RS06110
uniprot id: Q7M907
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

273121:WS RS02345
gene id: 273121:WS_RS02345
uniprot id: Q7MA50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

273121:WS RS06610
gene id: 273121:WS_RS06610
uniprot id: Q7MRG3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

273121:WS RS02785
gene id: 273121:WS_RS02785
uniprot id: Q7M9Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

273121:WS RS02975
gene id: 273121:WS_RS02975
uniprot id: Q7M9X4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent (By similarity).
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
messages: The Clp repeat (R) domain probably functions as a substrate-discriminating domain, recruiting aggregated proteins to the ClpB hexamer and/or stabilizing bound proteins. The NBD2 domain is responsible for oligomerization, whereas the NBD1 domain stabilizes the hexamer probably in an ATP-dependent manner. The movement of the coiled-coil domain is essential for ClpB ability to rescue proteins from an aggregated state, probably by pulling apart large aggregated proteins, which are bound between the coiled-coils motifs of adjacent ClpB subunits in the functional hexamer (By similarity).

273121:WS RS01330
gene id: 273121:WS_RS01330
uniprot id: Q7MAG5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

273121:WS RS10315
gene id: 273121:WS_RS10315
uniprot id: Q7M7N3
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

273121:WS RS04230
gene id: 273121:WS_RS04230
uniprot id: Q7M9I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

273121:WS RS08580
gene id: 273121:WS_RS08580
uniprot id: Q7M879
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

273121:WS RS04000
gene id: 273121:WS_RS04000
uniprot id: Q79HR6
names: Similarity
messages: Belongs to the universal stress protein A family.

273121:WS RS09260
gene id: 273121:WS_RS09260
uniprot id: Q7MQV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

273121:WS RS04815
gene id: 273121:WS_RS04815
uniprot id: Q7MRW0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

273121:WS RS06295
gene id: 273121:WS_RS06295
uniprot id: Q7M8Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

273121:WS RS05715
gene id: 273121:WS_RS05715
uniprot id: Q7M955
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273121:WS RS06200
gene id: 273121:WS_RS06200
uniprot id: Q7M8Z6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

273121:WS RS01030
gene id: 273121:WS_RS01030
uniprot id: Q7MAJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

273121:WS RS08915
gene id: 273121:WS_RS08915
uniprot id: Q7M841
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

273121:WS RS10255
gene id: 273121:WS_RS10255
uniprot id: Q7MQM6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

273121:WS RS01495
gene id: 273121:WS_RS01495
uniprot id: Q7MSM3
names: Subcellular Location Annotation
messages: Mitochondrion

273121:WS RS02745
gene id: 273121:WS_RS02745
uniprot id: Q7M9Z8
names: Similarity
messages: Belongs to the P(II) protein family.

273121:WS RS03855
gene id: 273121:WS_RS03855
uniprot id: Q7MS38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

273121:WS RS01675
gene id: 273121:WS_RS01675
uniprot id: Q7MSL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

273121:WS RS01955
gene id: 273121:WS_RS01955
uniprot id: Q7MA94
names: Similarity
messages: Belongs to the AOR/FOR family.

273121:WS RS03450
gene id: 273121:WS_RS03450
uniprot id: Q7M9S5
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

273121:WS RS08245
gene id: 273121:WS_RS08245
uniprot id: Q7MR38
names: Similarity
messages: Belongs to the UPF0763 family.

273121:WS RS00905
gene id: 273121:WS_RS00905
uniprot id: Q7MAL0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

273121:WS RS05440
gene id: 273121:WS_RS05440
uniprot id: Q7M974
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

273121:WS RS02970
gene id: 273121:WS_RS02970
uniprot id: Q7MSB3
names: Similarity
messages: Belongs to the peptidase S41A family.

273121:WS RS02960
gene id: 273121:WS_RS02960
uniprot id: Q7M9X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

273121:WS RS00185
gene id: 273121:WS_RS00185
uniprot id: Q7MAT7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

273121:WS RS01080
gene id: 273121:WS_RS01080
uniprot id: Q7MAJ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273121:WS RS03980
gene id: 273121:WS_RS03980
uniprot id: Q79HR7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: The fumarate reductase enzyme complex is required for fumarate respiration. This subunit anchors the complex in the membrane and binds a diheme cytochrome b.

273121:WS RS06635
gene id: 273121:WS_RS06635
uniprot id: Q7M8U9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

273121:WS RS07505
gene id: 273121:WS_RS07505
uniprot id: Q7M8K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Dps family.
messages: Cytoplasm

273121:WS RS05875
gene id: 273121:WS_RS05875
uniprot id: P59893
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

273121:WS RS04990
gene id: 273121:WS_RS04990
uniprot id: Q7M9B6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

273121:WS RS09715
gene id: 273121:WS_RS09715
uniprot id: Q7M7V6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273121:WS RS04270
gene id: 273121:WS_RS04270
uniprot id: Q7M9I6
names: Similarity
messages: Belongs to the GARS family.

273121:WS RS04880
gene id: 273121:WS_RS04880
uniprot id: Q7M9C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

273121:WS RS00985
gene id: 273121:WS_RS00985
uniprot id: Q7MAK0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

273121:WS RS04470
gene id: 273121:WS_RS04470
uniprot id: Q7M9H0
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

273121:WS RS09890
gene id: 273121:WS_RS09890
uniprot id: Q7M7T4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273121:WS RS08895
gene id: 273121:WS_RS08895
uniprot id: Q7M845
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

273121:WS RS06970
gene id: 273121:WS_RS06970
uniprot id: Q7M8S1
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

273121:WS RS07800
gene id: 273121:WS_RS07800
uniprot id: Q7M8H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

273121:WS RS10200
gene id: 273121:WS_RS10200
uniprot id: Q7M7P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

273121:WS RS01990
gene id: 273121:WS_RS01990
uniprot id: Q7MA90
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS09995
gene id: 273121:WS_RS09995
uniprot id: Q7M7S2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

273121:WS RS07205
gene id: 273121:WS_RS07205
uniprot id: Q7M8N8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

273121:WS RS07565
gene id: 273121:WS_RS07565
uniprot id: Q7M8K2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

273121:WS RS09630
gene id: 273121:WS_RS09630
uniprot id: Q7MQS5
names: Similarity
messages: Belongs to the UPF0751 family.

273121:WS RS07295
gene id: 273121:WS_RS07295
uniprot id: Q7MRA2
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS03885
gene id: 273121:WS_RS03885
uniprot id: Q7M9M9
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

273121:WS RS04955
gene id: 273121:WS_RS04955
uniprot id: Q7M9C1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

273121:WS RS08000
gene id: 273121:WS_RS08000
uniprot id: Q7M8F0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

273121:WS RS07305
gene id: 273121:WS_RS07305
uniprot id: Q7M8M8
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

273121:WS RS07140
gene id: 273121:WS_RS07140
uniprot id: Q7M8P6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

273121:WS RS08520
gene id: 273121:WS_RS08520
uniprot id: Q7M886
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

273121:WS RS08280
gene id: 273121:WS_RS08280
uniprot id: Q7M8B2
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

273121:WS RS10300
gene id: 273121:WS_RS10300
uniprot id: Q7M7N6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

273121:WS RS08065
gene id: 273121:WS_RS08065
uniprot id: Q7M8D8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

273121:WS RS02720
gene id: 273121:WS_RS02720
uniprot id: Q7MSD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

273121:WS RS08310
gene id: 273121:WS_RS08310
uniprot id: Q79HP0
names: Similarity
messages: Belongs to the class-I fumarase family.

273121:WS RS09760
gene id: 273121:WS_RS09760
uniprot id: Q7M7V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

273121:WS RS03930
gene id: 273121:WS_RS03930
uniprot id: Q7M9M2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

273121:WS RS06180
gene id: 273121:WS_RS06180
uniprot id: Q7M8Z9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

273121:WS RS08660
gene id: 273121:WS_RS08660
uniprot id: Q7M868
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS09430
gene id: 273121:WS_RS09430
uniprot id: Q7M7Y2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

273121:WS RS09345
gene id: 273121:WS_RS09345
uniprot id: Q7M7Z5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

273121:WS RS08795
gene id: 273121:WS_RS08795
uniprot id: Q7MQZ8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

273121:WS RS05260
gene id: 273121:WS_RS05260
uniprot id: Q7MRR8
names: Similarity
messages: Belongs to the TrbI/VirB10 family.

273121:WS RS10010
gene id: 273121:WS_RS10010
uniprot id: Q7M7S1
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

273121:WS RS06020
gene id: 273121:WS_RS06020
uniprot id: Q7MRK5
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS05495
gene id: 273121:WS_RS05495
uniprot id: P27273
names: Cofactor
names: Function
names: Subunit
messages: Binds 4 [4Fe-4S] clusters.
messages: Formate dehydrogenase is a membrane-bound complex, formed of at least three different subunits.
messages: This chain is an electron transfer unit containing 18 cysteine residues, 16 of which occur in four clusters.

273121:WS RS03030
gene id: 273121:WS_RS03030
uniprot id: P60095
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

273121:WS RS00020
gene id: 273121:WS_RS00020
uniprot id: Q7MSY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

273121:WS RS08075
gene id: 273121:WS_RS08075
uniprot id: Q7M8D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

273121:WS RS03935
gene id: 273121:WS_RS03935
uniprot id: Q7M9M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

273121:WS RS08215
gene id: 273121:WS_RS08215
uniprot id: Q7M8C0
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

273121:WS RS09020
gene id: 273121:WS_RS09020
uniprot id: Q7M828
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

273121:WS RS00315
gene id: 273121:WS_RS00315
uniprot id: Q7MSV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

273121:WS RS00505
gene id: 273121:WS_RS00505
uniprot id: Q7MAP7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

273121:WS RS01185
gene id: 273121:WS_RS01185
uniprot id: Q7MSQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta/beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription (By similarity).

273121:WS RS09045
gene id: 273121:WS_RS09045
uniprot id: Q7M823
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

273121:WS RS09400
gene id: 273121:WS_RS09400
uniprot id: Q7M7Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

273121:WS RS03110
gene id: 273121:WS_RS03110
uniprot id: Q7MSA2
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS00180
gene id: 273121:WS_RS00180
uniprot id: Q7MAT8
names: Similarity
messages: Belongs to the polysaccharide synthase family.

273121:WS RS07455
gene id: 273121:WS_RS07455
uniprot id: Q7M8L2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

273121:WS RS02715
gene id: 273121:WS_RS02715
uniprot id: Q7MA01
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

273121:WS RS08390
gene id: 273121:WS_RS08390
uniprot id: Q7M8A5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

273121:WS RS01190
gene id: 273121:WS_RS01190
uniprot id: Q7MAH7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

273121:WS RS10685
gene id: 273121:WS_RS10685
uniprot id: Q7MRA7
names: Similarity
messages: Belongs to the hemerythrin family.

273121:WS RS00550
gene id: 273121:WS_RS00550
uniprot id: P31076
names: Function
names: Subunit
messages: Component of the phosphorylative electron transport system with polysulfide as the terminal acceptor.
messages: Functional polysulfide reductase is made up of three different (A, B, and C) subunits.

273121:WS RS04535
gene id: 273121:WS_RS04535
uniprot id: Q7M9G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

273121:WS RS07615
gene id: 273121:WS_RS07615
uniprot id: Q7MR71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

273121:WS RS09120
gene id: 273121:WS_RS09120
uniprot id: Q7MQW9
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.

273121:WS RS02470
gene id: 273121:WS_RS02470
uniprot id: Q7MA31
names: Similarity
messages: Belongs to the RutC family.

273121:WS RS06030
gene id: 273121:WS_RS06030
uniprot id: Q7MRK3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

273121:WS RS02870
gene id: 273121:WS_RS02870
uniprot id: Q7MSC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

273121:WS RS01165
gene id: 273121:WS_RS01165
uniprot id: Q7MAH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

273121:WS RS06225
gene id: 273121:WS_RS06225
uniprot id: Q7M8Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

273121:WS RS05505
gene id: 273121:WS_RS05505
uniprot id: P28181
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

273121:WS RS07500
gene id: 273121:WS_RS07500
uniprot id: Q7MR82
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS02665
gene id: 273121:WS_RS02665
uniprot id: Q7MA09
names: Similarity
messages: Belongs to the GSP E family.

273121:WS RS01230
gene id: 273121:WS_RS01230
uniprot id: Q7MSP5
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS07160
gene id: 273121:WS_RS07160
uniprot id: Q7M8P4
names: Similarity
messages: Belongs to the nitroreductase family.

273121:WS RS09125
gene id: 273121:WS_RS09125
uniprot id: Q7M818
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

273121:WS RS06650
gene id: 273121:WS_RS06650
uniprot id: Q7M8U8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg-115 inactivates the nitrogenase reductase and regulates nitrogenase activity.

273121:WS RS10735
gene id: 273121:WS_RS10735
uniprot id: Q7MR03
names: Similarity
messages: Belongs to the UPF0251 family.

273121:WS RS00430
gene id: 273121:WS_RS00430
uniprot id: Q7MAQ8
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

273121:WS RS07560
gene id: 273121:WS_RS07560
uniprot id: Q7M8K3
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

273121:WS RS08150
gene id: 273121:WS_RS08150
uniprot id: Q7M8C7
names: Similarity
messages: Belongs to the aspartokinase family.

273121:WS RS05680
gene id: 273121:WS_RS05680
uniprot id: Q7M959
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

273121:WS RS08575
gene id: 273121:WS_RS08575
uniprot id: Q7M880
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

273121:WS RS02270
gene id: 273121:WS_RS02270
uniprot id: P42482
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

273121:WS RS02460
gene id: 273121:WS_RS02460
uniprot id: Q7MA32
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

273121:WS RS01725
gene id: 273121:WS_RS01725
uniprot id: Q7MSL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

273121:WS RS08315
gene id: 273121:WS_RS08315
uniprot id: Q79HN9
names: Similarity
messages: Belongs to the class-I fumarase family.

273121:WS RS02955
gene id: 273121:WS_RS02955
uniprot id: Q7M9X7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

273121:WS RS02310
gene id: 273121:WS_RS02310
uniprot id: Q7MA57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

273121:WS RS06175
gene id: 273121:WS_RS06175
uniprot id: Q7M900
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

273121:WS RS09720
gene id: 273121:WS_RS09720
uniprot id: Q7M7V5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

273121:WS RS02700
gene id: 273121:WS_RS02700
uniprot id: Q7MA04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

273121:WS RS04855
gene id: 273121:WS_RS04855
uniprot id: Q7M9D0
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

273121:WS RS01350
gene id: 273121:WS_RS01350
uniprot id: Q7MAG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

273121:WS RS03985
gene id: 273121:WS_RS03985
uniprot id: P17596
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: Part of an enzyme complex containing three subunits: a flavoprotein (frdA), an iron-sulfur protein (frdB), and diheme cytochrome b (frdC).
messages: The fumarate reductase enzyme complex is required for fumarate respiration using formate or sulfide as electron donor.

273121:WS RS00480
gene id: 273121:WS_RS00480
uniprot id: Q7MAQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

273121:WS RS05065
gene id: 273121:WS_RS05065
uniprot id: Q7M9B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

273121:WS RS03185
gene id: 273121:WS_RS03185
uniprot id: Q7M9V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

273121:WS RS07100
gene id: 273121:WS_RS07100
uniprot id: Q7M8Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

273121:WS RS04100
gene id: 273121:WS_RS04100
uniprot id: Q7M9K2
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

273121:WS RS08920
gene id: 273121:WS_RS08920
uniprot id: Q7M840
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

273121:WS RS07900
gene id: 273121:WS_RS07900
uniprot id: Q7M8G0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

273121:WS RS10475
gene id: 273121:WS_RS10475
uniprot id: Q7M7L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

273121:WS RS06430
gene id: 273121:WS_RS06430
uniprot id: Q7MRH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

273121:WS RS06125
gene id: 273121:WS_RS06125
uniprot id: Q7M904
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

273121:WS RS07810
gene id: 273121:WS_RS07810
uniprot id: Q7M8H4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

273121:WS RS07685
gene id: 273121:WS_RS07685
uniprot id: Q7MR63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Slam family.
messages: Cell outer membrane
messages: Membrane

273121:WS RS02230
gene id: 273121:WS_RS02230
uniprot id: Q7MA63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

273121:WS RS02335
gene id: 273121:WS_RS02335
uniprot id: Q7MA52
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

273121:WS RS03705
gene id: 273121:WS_RS03705
uniprot id: Q7M9P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

273121:WS RS03070
gene id: 273121:WS_RS03070
uniprot id: Q7M9W2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

273121:WS RS00250
gene id: 273121:WS_RS00250
uniprot id: Q7MAS9
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS06935
gene id: 273121:WS_RS06935
uniprot id: Q7M8S3
names: Similarity
messages: Belongs to the citrate synthase family.

273121:WS RS07750
gene id: 273121:WS_RS07750
uniprot id: Q7M8I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

273121:WS RS06130
gene id: 273121:WS_RS06130
uniprot id: Q7M903
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

273121:WS RS03915
gene id: 273121:WS_RS03915
uniprot id: Q7M9M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

273121:WS RS09405
gene id: 273121:WS_RS09405
uniprot id: Q7M7Y6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

273121:WS RS07710
gene id: 273121:WS_RS07710
uniprot id: Q7M8I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

273121:WS RS03950
gene id: 273121:WS_RS03950
uniprot id: Q7M9L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

273121:WS RS01285
gene id: 273121:WS_RS01285
uniprot id: Q7MAG7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

273121:WS RS00925
gene id: 273121:WS_RS00925
uniprot id: Q7MAK7
names: Cofactor
names: Similarity
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.

273121:WS RS00955
gene id: 273121:WS_RS00955
uniprot id: Q7MAK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

273121:WS RS00345
gene id: 273121:WS_RS00345
uniprot id: Q7MSV4
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

273121:WS RS05460
gene id: 273121:WS_RS05460
uniprot id: Q7MRQ1
names: Similarity
messages: Belongs to the UPF0166 family.

273121:WS RS03200
gene id: 273121:WS_RS03200
uniprot id: Q7M9U8
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Homodimer.

273121:WS RS03160
gene id: 273121:WS_RS03160
uniprot id: Q7M9V2
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS03020
gene id: 273121:WS_RS03020
uniprot id: Q7M9W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

273121:WS RS00005
gene id: 273121:WS_RS00005
uniprot id: Q7MSY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

273121:WS RS09035
gene id: 273121:WS_RS09035
uniprot id: Q7M825
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Membrane anchor subunit of 8-methylmenaquinol:fumarate reductase (MFR), that catalyzes the reduction of fumarate using 8-methylmenaquinol-6 as electron donor. The complex shows no succinate oxidation activity. Is involved in anaerobic metabolism. SdhE likely contains the quinol/quinone binding site.
messages: Periplasm
messages: The MFR complex is composed of three subunits: a flavoprotein (SdhA), an iron-sulfur protein (SdhB), and one hydrophobic anchor protein (SdhE).

273121:WS RS09415
gene id: 273121:WS_RS09415
uniprot id: Q7M7Y5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273121:WS RS08905
gene id: 273121:WS_RS08905
uniprot id: Q7M843
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

273121:WS RS09855
gene id: 273121:WS_RS09855
uniprot id: Q7M7T9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

273121:WS RS04935
gene id: 273121:WS_RS04935
uniprot id: Q7M9C4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

273121:WS RS02015
gene id: 273121:WS_RS02015
uniprot id: Q7MA88
names: Similarity
messages: Belongs to the P(II) protein family.

273121:WS RS01005
gene id: 273121:WS_RS01005
uniprot id: Q7MSR5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

273121:WS RS05510
gene id: 273121:WS_RS05510
uniprot id: Q7MRP7
names: Similarity
messages: Belongs to the DinB family.

273121:WS RS07610
gene id: 273121:WS_RS07610
uniprot id: Q7MR72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

273121:WS RS01555
gene id: 273121:WS_RS01555
uniprot id: Q7MSM0
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS04165
gene id: 273121:WS_RS04165
uniprot id: Q7M9J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

273121:WS RS10405
gene id: 273121:WS_RS10405
uniprot id: Q7M7M4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

273121:WS RS04070
gene id: 273121:WS_RS04070
uniprot id: Q7MS25
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS00525
gene id: 273121:WS_RS00525
uniprot id: Q7MAP4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

273121:WS RS08185
gene id: 273121:WS_RS08185
uniprot id: Q7M8C3
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS09230
gene id: 273121:WS_RS09230
uniprot id: Q7M805
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

273121:WS RS01635
gene id: 273121:WS_RS01635
uniprot id: Q7MAD1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

273121:WS RS07910
gene id: 273121:WS_RS07910
uniprot id: O34247
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

273121:WS RS00160
gene id: 273121:WS_RS00160
uniprot id: Q7MSX1
names: Similarity
messages: Belongs to the YciI family.

273121:WS RS00220
gene id: 273121:WS_RS00220
uniprot id: Q7MSW6
names: Similarity
messages: Belongs to the asparagine synthetase family.

273121:WS RS01100
gene id: 273121:WS_RS01100
uniprot id: Q7MAI7
names: Similarity
messages: Belongs to the TrpF family.

273121:WS RS07930
gene id: 273121:WS_RS07930
uniprot id: P31875
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: B-type cytochrome that interacts with quinones and anchor the hydrogenase to the membrane.
messages: Belongs to the HupC/HyaC/HydC family.
messages: Cell membrane

273121:WS RS03615
gene id: 273121:WS_RS03615
uniprot id: Q7M9Q8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

273121:WS RS05855
gene id: 273121:WS_RS05855
uniprot id: Q7M935
names: Similarity
messages: Belongs to the MipA/OmpV family.

273121:WS RS02865
gene id: 273121:WS_RS02865
uniprot id: Q7M9Y5
names: Similarity
messages: Belongs to the ribF family.

273121:WS RS01670
gene id: 273121:WS_RS01670
uniprot id: Q7MAC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.

273121:WS RS07985
gene id: 273121:WS_RS07985
uniprot id: Q7M8F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

273121:WS RS01550
gene id: 273121:WS_RS01550
uniprot id: Q7MAD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

273121:WS RS00135
gene id: 273121:WS_RS00135
uniprot id: Q7MAU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

273121:WS RS06420
gene id: 273121:WS_RS06420
uniprot id: Q7M8X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

273121:WS RS06625
gene id: 273121:WS_RS06625
uniprot id: Q7MRG0
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

273121:WS RS08400
gene id: 273121:WS_RS08400
uniprot id: Q7M8A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

273121:WS RS08620
gene id: 273121:WS_RS08620
uniprot id: Q7MR08
names: Similarity
messages: Belongs to the peptidase A31 family.

273121:WS RS03085
gene id: 273121:WS_RS03085
uniprot id: Q7MSA5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

273121:WS RS09960
gene id: 273121:WS_RS09960
uniprot id: Q7M7S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

273121:WS RS00295
gene id: 273121:WS_RS00295
uniprot id: Q7MSW1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

273121:WS RS08550
gene id: 273121:WS_RS08550
uniprot id: Q7M883
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

273121:WS RS04540
gene id: 273121:WS_RS04540
uniprot id: Q7M9G2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

273121:WS RS07240
gene id: 273121:WS_RS07240
uniprot id: Q7MRA6
names: Similarity
messages: Belongs to the hemerythrin family.

273121:WS RS09425
gene id: 273121:WS_RS09425
uniprot id: Q7M7Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

273121:WS RS08465
gene id: 273121:WS_RS08465
uniprot id: Q7M895
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

273121:WS RS09605
gene id: 273121:WS_RS09605
uniprot id: Q7M7W9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

273121:WS RS05820
gene id: 273121:WS_RS05820
uniprot id: Q7M938
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

273121:WS RS09860
gene id: 273121:WS_RS09860
uniprot id: Q7M7T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Cell inner membrane
messages: Membrane

273121:WS RS01090
gene id: 273121:WS_RS01090
uniprot id: Q7MAI9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

273121:WS RS06330
gene id: 273121:WS_RS06330
uniprot id: Q7MRI5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

273121:WS RS09650
gene id: 273121:WS_RS09650
uniprot id: Q7M7W2
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

273121:WS RS05405
gene id: 273121:WS_RS05405
uniprot id: Q7M977
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

273121:WS RS00255
gene id: 273121:WS_RS00255
uniprot id: Q7MAS8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

273121:WS RS03490
gene id: 273121:WS_RS03490
uniprot id: Q7M9S0
names: Similarity
messages: Belongs to the peptidase S11 family.

273121:WS RS02435
gene id: 273121:WS_RS02435
uniprot id: Q7MA35
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

273121:WS RS07570
gene id: 273121:WS_RS07570
uniprot id: Q7M8K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

273121:WS RS05420
gene id: 273121:WS_RS05420
uniprot id: Q7M976
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

273121:WS RS02295
gene id: 273121:WS_RS02295
uniprot id: P60106
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

273121:WS RS01525
gene id: 273121:WS_RS01525
uniprot id: Q7MAE1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

273121:WS RS08035
gene id: 273121:WS_RS08035
uniprot id: Q7M8E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

273121:WS RS04670
gene id: 273121:WS_RS04670
uniprot id: Q9S1E6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.
messages: Cell inner membrane
messages: Heterodimer with NrfA.
messages: Subunit of the nitrite reductase complex that mediates electron transfer from quinol to the catalytic subunit.
messages: The N-terminus is blocked.

273121:WS RS03225
gene id: 273121:WS_RS03225
uniprot id: P50286
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the asparaginase 1 family.
messages: Cytoplasm
messages: Homotetramer.

273121:WS RS07520
gene id: 273121:WS_RS07520
uniprot id: Q7M8K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

273121:WS RS06075
gene id: 273121:WS_RS06075
uniprot id: Q7M914
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

273121:WS RS03740
gene id: 273121:WS_RS03740
uniprot id: Q7MS46
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

273121:WS RS09285
gene id: 273121:WS_RS09285
uniprot id: Q7M801
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

273121:WS RS08060
gene id: 273121:WS_RS08060
uniprot id: Q7M8D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

273121:WS RS01035
gene id: 273121:WS_RS01035
uniprot id: Q7MSR2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

273121:WS RS00405
gene id: 273121:WS_RS00405
uniprot id: Q7MAR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

273121:WS RS04945
gene id: 273121:WS_RS04945
uniprot id: Q7M9C2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

273121:WS RS00440
gene id: 273121:WS_RS00440
uniprot id: Q7MAQ7
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

273121:WS RS08240
gene id: 273121:WS_RS08240
uniprot id: Q7M8B6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

273121:WS RS08005
gene id: 273121:WS_RS08005
uniprot id: Q7M8E9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

273121:WS RS10075
gene id: 273121:WS_RS10075
uniprot id: Q7M7R1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

273121:WS RS01345
gene id: 273121:WS_RS01345
uniprot id: Q7MSN3
names: Similarity
messages: Belongs to the YggT family.

273121:WS RS06930
gene id: 273121:WS_RS06930
uniprot id: Q7M8S4
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

273121:WS RS08115
gene id: 273121:WS_RS08115
uniprot id: Q7M8D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

273121:WS RS07815
gene id: 273121:WS_RS07815
uniprot id: Q7MR56
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

273121:WS RS07925
gene id: 273121:WS_RS07925
uniprot id: P31876
names: Similarity
messages: Belongs to the peptidase A31 family.

273121:WS RS09375
gene id: 273121:WS_RS09375
uniprot id: Q7M7Z2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

273121:WS RS06775
gene id: 273121:WS_RS06775
uniprot id: Q7M8T6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

273121:WS RS03540
gene id: 273121:WS_RS03540
uniprot id: P27273
names: Cofactor
names: Function
names: Subunit
messages: Binds 4 [4Fe-4S] clusters.
messages: Formate dehydrogenase is a membrane-bound complex, formed of at least three different subunits.
messages: This chain is an electron transfer unit containing 18 cysteine residues, 16 of which occur in four clusters.

273121:WS RS09155
gene id: 273121:WS_RS09155
uniprot id: Q7MQW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

273121:WS RS07580
gene id: 273121:WS_RS07580
uniprot id: Q7M8K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

273121:WS RS01975
gene id: 273121:WS_RS01975
uniprot id: Q7MSI8
names: Similarity
messages: Belongs to the UPF0306 family.

273121:WS RS00270
gene id: 273121:WS_RS00270
uniprot id: Q7MAS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

273121:WS RS06095
gene id: 273121:WS_RS06095
uniprot id: Q7M910
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

273121:WS RS02305
gene id: 273121:WS_RS02305
uniprot id: Q7MA58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

273121:WS RS07090
gene id: 273121:WS_RS07090
uniprot id: Q7M8Q2
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

273121:WS RS00630
gene id: 273121:WS_RS00630
uniprot id: Q7MAN4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

273121:WS RS02565
gene id: 273121:WS_RS02565
uniprot id: Q7MA16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

273121:WS RS09485
gene id: 273121:WS_RS09485
uniprot id: Q7M7X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

273121:WS RS00750
gene id: 273121:WS_RS00750
uniprot id: Q7MAM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

273121:WS RS07825
gene id: 273121:WS_RS07825
uniprot id: Q7M8H2
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS09905
gene id: 273121:WS_RS09905
uniprot id: Q7M7T2
names: Similarity
messages: Belongs to the sigma-54 factor family.

273121:WS RS03080
gene id: 273121:WS_RS03080
uniprot id: Q7M9W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

273121:WS RS06460
gene id: 273121:WS_RS06460
uniprot id: Q7M8W6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

273121:WS RS01615
gene id: 273121:WS_RS01615
uniprot id: Q7MAD3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

273121:WS RS00400
gene id: 273121:WS_RS00400
uniprot id: Q7MAR1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

273121:WS RS07325
gene id: 273121:WS_RS07325
uniprot id: Q7M8M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

273121:WS RS00385
gene id: 273121:WS_RS00385
uniprot id: Q7MAR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane

273121:WS RS08510
gene id: 273121:WS_RS08510
uniprot id: Q7M888
names: Similarity
messages: Belongs to the ModE family.

273121:WS RS08805
gene id: 273121:WS_RS08805
uniprot id: Q7MQZ6
names: Subcellular Location Annotation
messages: Cytoplasm

273121:WS RS06255
gene id: 273121:WS_RS06255
uniprot id: Q7M8Y9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

273121:WS RS07085
gene id: 273121:WS_RS07085
uniprot id: Q7M8Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

273121:WS RS10250
gene id: 273121:WS_RS10250
uniprot id: Q7MQM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

273121:WS RS09025
gene id: 273121:WS_RS09025
uniprot id: Q7M827
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell membrane
messages: Flavoprotein subunit of 8-methylmenaquinol:fumarate reductase (MFR), that catalyzes the reduction of fumarate using 8-methylmenaquinol-6 as electron donor. The complex shows no succinate oxidation activity. Is involved in anaerobic metabolism. SdhA contains the dicarboxylate reduction site.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.
messages: The MFR complex is composed of three subunits: a flavoprotein (SdhA), an iron-sulfur protein (SdhB), and one hydrophobic anchor protein (SdhE).

273121:WS RS00040
gene id: 273121:WS_RS00040
uniprot id: Q7MSX9
names: Similarity
messages: Belongs to the universal stress protein A family.

273121:WS RS08890
gene id: 273121:WS_RS08890
uniprot id: Q7MQY6
names: Similarity
messages: Belongs to the XseB family.

273121:WS RS02540
gene id: 273121:WS_RS02540
uniprot id: P42470
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

273121:WS RS09215
gene id: 273121:WS_RS09215
uniprot id: Q7M806
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

273121:WS RS00285
gene id: 273121:WS_RS00285
uniprot id: Q7MAS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

273121:WS RS07895
gene id: 273121:WS_RS07895
uniprot id: Q7M8G1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

273121:WS RS06660
gene id: 273121:WS_RS06660
uniprot id: Q7M8U7
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

273121:WS RS06445
gene id: 273121:WS_RS06445
uniprot id: Q7M8W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

273121:WS RS10135
gene id: 273121:WS_RS10135
uniprot id: Q7M7Q4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273121:WS RS01370
gene id: 273121:WS_RS01370
uniprot id: Q7MAG0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

273121:WS RS00205
gene id: 273121:WS_RS00205
uniprot id: Q7MSW7
names: Similarity
messages: Belongs to the asparagine synthetase family.

273121:WS RS10100
gene id: 273121:WS_RS10100
uniprot id: Q7MQN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

273121:WS RS06165
gene id: 273121:WS_RS06165
uniprot id: Q7MRJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

273121:WS RS01695
gene id: 273121:WS_RS01695
uniprot id: Q7MAC2
names: Similarity
messages: Belongs to the UDPGP type 2 family.

273121:WS RS04495
gene id: 273121:WS_RS04495
uniprot id: Q7MRY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

273121:WS RS02490
gene id: 273121:WS_RS02490
uniprot id: Q7MA27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

273121:WS RS02330
gene id: 273121:WS_RS02330
uniprot id: Q7MA53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

273121:WS RS05660
gene id: 273121:WS_RS05660
uniprot id: Q7M961
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

273121:WS RS02355
gene id: 273121:WS_RS02355
uniprot id: Q7MA48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

273121:WS RS08735
gene id: 273121:WS_RS08735
uniprot id: Q7M858
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

273121:WS RS02945
gene id: 273121:WS_RS02945
uniprot id: Q7M9X8
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

273121:WS RS08275
gene id: 273121:WS_RS08275
uniprot id: Q7M8B3
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

273121:WS RS00900
gene id: 273121:WS_RS00900
uniprot id: Q7MSS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

273121:WS RS09800
gene id: 273121:WS_RS09800
uniprot id: Q7M7U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

273121:WS RS04195
gene id: 273121:WS_RS04195
uniprot id: Q7M9J3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

273121:WS RS00305
gene id: 273121:WS_RS00305
uniprot id: Q7MAS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

273121:WS RS09470
gene id: 273121:WS_RS09470
uniprot id: Q7M7X7
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

273121:WS RS07475
gene id: 273121:WS_RS07475
uniprot id: Q7MBG4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

273121:WS RS05810
gene id: 273121:WS_RS05810
uniprot id: Q7M940
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

273121:WS RS02875
gene id: 273121:WS_RS02875
uniprot id: Q7MSC2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

273121:WS RS00340
gene id: 273121:WS_RS00340
uniprot id: Q7MAR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

273121:WS RS05960
gene id: 273121:WS_RS05960
uniprot id: Q7M926
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

273121:WS RS03545
gene id: 273121:WS_RS03545
uniprot id: Q4KKT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

273121:WS RS01405
gene id: 273121:WS_RS01405
uniprot id: Q7MSM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

273121:WS RS02675
gene id: 273121:WS_RS02675
uniprot id: Q7MA07
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.
messages: Homodimer.

273121:WS RS01335
gene id: 273121:WS_RS01335
uniprot id: Q7MSN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

273121:WS RS04570
gene id: 273121:WS_RS04570
uniprot id: Q7MRY0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273121:WS RS05900
gene id: 273121:WS_RS05900
uniprot id: Q7M930
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

273121:WS RS00995
gene id: 273121:WS_RS00995
uniprot id: Q7MSR6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

273121:WS RS03015
gene id: 273121:WS_RS03015
uniprot id: Q7M9X0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

273121:WS RS03955
gene id: 273121:WS_RS03955
uniprot id: Q7M9L8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

273121:WS RS01270
gene id: 273121:WS_RS01270
uniprot id: Q7MAG9
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS08500
gene id: 273121:WS_RS08500
uniprot id: Q7M890
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

273121:WS RS07285
gene id: 273121:WS_RS07285
uniprot id: Q7M8N0
names: Similarity
messages: Belongs to the UbiD family.

273121:WS RS01450
gene id: 273121:WS_RS01450
uniprot id: Q7MAF0
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

273121:WS RS00120
gene id: 273121:WS_RS00120
uniprot id: Q7MAU2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

273121:WS RS10420
gene id: 273121:WS_RS10420
uniprot id: Q7M7M2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

273121:WS RS09040
gene id: 273121:WS_RS09040
uniprot id: Q7M824
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

273121:WS RS02085
gene id: 273121:WS_RS02085
uniprot id: Q7MA78
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

273121:WS RS00275
gene id: 273121:WS_RS00275
uniprot id: Q7MAS4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

273121:WS RS07765
gene id: 273121:WS_RS07765
uniprot id: Q7MR60
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

273121:WS RS03560
gene id: 273121:WS_RS03560
uniprot id: Q7M9R3
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

273121:WS RS07990
gene id: 273121:WS_RS07990
uniprot id: Q7M8F2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

273121:WS RS00280
gene id: 273121:WS_RS00280
uniprot id: Q7MAS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

273121:WS RS11240
gene id: 273121:WS_RS11240
uniprot id: Q7M8X5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

273121:WS RS09365
gene id: 273121:WS_RS09365
uniprot id: Q7M7Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

273121:WS RS09385
gene id: 273121:WS_RS09385
uniprot id: Q7M7Z0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

273121:WS RS03045
gene id: 273121:WS_RS03045
uniprot id: Q7M9W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

273121:WS RS10235
gene id: 273121:WS_RS10235
uniprot id: Q7MQM9
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS07330
gene id: 273121:WS_RS07330
uniprot id: Q7M8M5
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

273121:WS RS01655
gene id: 273121:WS_RS01655
uniprot id: Q7MAC8
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

273121:WS RS07945
gene id: 273121:WS_RS07945
uniprot id: Q7M8F9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm

273121:WS RS05620
gene id: 273121:WS_RS05620
uniprot id: Q7M963
names: Disruption Phenotype
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB. Transfers electrons to NapA subunit, thus allowing electron flow between membrane and periplasm. Essential for periplasmic nitrate reduction with nitrate as the terminal electron acceptor.
messages: Mutants fail to grow by nitrate respiration and also fail to reduce nitrate and contain increased amounts of NapA.
messages: Periplasm

273121:WS RS07075
gene id: 273121:WS_RS07075
uniprot id: Q7M8Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

273121:WS RS03990
gene id: 273121:WS_RS03990
uniprot id: P17412
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD covalently per subunit.
messages: Cell inner membrane
messages: Part of an enzyme complex containing three subunits: a flavoprotein (frdA), an iron-sulfur protein (frdB), and diheme cytochrome b (frdC).
messages: The fumarate reductase enzyme complex is required for fumarate respiration using formate or sulfide as electron donor.

273121:WS RS07775
gene id: 273121:WS_RS07775
uniprot id: Q7M8H8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

273121:WS RS02075
gene id: 273121:WS_RS02075
uniprot id: Q7MA79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

273121:WS RS01120
gene id: 273121:WS_RS01120
uniprot id: Q7MAI3
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

273121:WS RS01375
gene id: 273121:WS_RS01375
uniprot id: Q7MAF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

273121:WS RS07400
gene id: 273121:WS_RS07400
uniprot id: Q7MR93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

273121:WS RS07845
gene id: 273121:WS_RS07845
uniprot id: Q7M8G9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

273121:WS RS05635
gene id: 273121:WS_RS05635
uniprot id: Q7M962
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

273121:WS RS06195
gene id: 273121:WS_RS06195
uniprot id: Q7M8Z7
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

273121:WS RS03035
gene id: 273121:WS_RS03035
uniprot id: Q7M9W6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

273121:WS RS08080
gene id: 273121:WS_RS08080
uniprot id: Q7M8D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

273121:WS RS02395
gene id: 273121:WS_RS02395
uniprot id: Q7MA40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

273121:WS RS07805
gene id: 273121:WS_RS07805
uniprot id: Q7MR57
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273121:WS RS00110
gene id: 273121:WS_RS00110
uniprot id: Q7MAU3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

273121:WS RS03995
gene id: 273121:WS_RS03995
uniprot id: P17413
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diheme cytochrome b FrdC family.
messages: Binds 2 heme b molecules per subunit, called the proximal (bP) and distal (bD) hemes.
messages: Cell inner membrane
messages: Part of an enzyme complex containing three subunits: a flavoprotein (frdA), an iron-sulfur protein (frdB), and diheme cytochrome b (frdC).
messages: The fumarate reductase enzyme complex is required for fumarate respiration using formate or sulfide as electron donor. This subunit anchors the complex in the membrane and binds a diheme cytochrome b.

273121:WS RS03805
gene id: 273121:WS_RS03805
uniprot id: Q7M9N5
names: Similarity
messages: Belongs to the HypD family.

273121:WS RS01645
gene id: 273121:WS_RS01645
uniprot id: Q7MAC9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e. capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

273121:WS RS02670
gene id: 273121:WS_RS02670
uniprot id: Q7MA08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

273121:WS RS05060
gene id: 273121:WS_RS05060
uniprot id: Q7M9B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

273121:WS RS01705
gene id: 273121:WS_RS01705
uniprot id: Q7MAC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

273121:WS RS06435
gene id: 273121:WS_RS06435
uniprot id: Q7M8W9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

273121:WS RS06115
gene id: 273121:WS_RS06115
uniprot id: Q7M906
names: Similarity
messages: Belongs to the transglycosylase Slt family.

273121:WS RS02380
gene id: 273121:WS_RS02380
uniprot id: Q7MA43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

273121:WS RS00210
gene id: 273121:WS_RS00210
uniprot id: Q7MAT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

273121:WS RS06540
gene id: 273121:WS_RS06540
uniprot id: Q7M8V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

273121:WS RS00755
gene id: 273121:WS_RS00755
uniprot id: Q7MAM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

273121:WS RS01195
gene id: 273121:WS_RS01195
uniprot id: Q7MAH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

273121:WS RS00395
gene id: 273121:WS_RS00395
uniprot id: Q7MAR2
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS06260
gene id: 273121:WS_RS06260
uniprot id: Q7M8Y8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

273121:WS RS06750
gene id: 273121:WS_RS06750
uniprot id: Q7M8U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

273121:WS RS08770
gene id: 273121:WS_RS08770
uniprot id: Q7M855
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

273121:WS RS08330
gene id: 273121:WS_RS08330
uniprot id: Q7MR31
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

273121:WS RS05080
gene id: 273121:WS_RS05080
uniprot id: Q7M9A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

273121:WS RS09625
gene id: 273121:WS_RS09625
uniprot id: Q7M7W6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Homodimer.

273121:WS RS04820
gene id: 273121:WS_RS04820
uniprot id: Q7M9D4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

273121:WS RS04125
gene id: 273121:WS_RS04125
uniprot id: Q7M9K0
names: Similarity
messages: Belongs to the AAA ATPase family.

273121:WS RS05150
gene id: 273121:WS_RS05150
uniprot id: Q7M999
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

273121:WS RS07095
gene id: 273121:WS_RS07095
uniprot id: Q7MRB9
names: Caution
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273121:WS RS06755
gene id: 273121:WS_RS06755
uniprot id: Q7M8U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
messages: Cell inner membrane
messages: Homodimer.
messages: Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.

273121:WS RS02205
gene id: 273121:WS_RS02205
uniprot id: Q7MA65
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

273121:WS RS08370
gene id: 273121:WS_RS08370
uniprot id: Q7M8A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

273121:WS RS03310
gene id: 273121:WS_RS03310
uniprot id: Q7M9U0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

273121:WS RS09810
gene id: 273121:WS_RS09810
uniprot id: Q7M7U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

273121:WS RS08405
gene id: 273121:WS_RS08405
uniprot id: Q7M8A2
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS05805
gene id: 273121:WS_RS05805
uniprot id: Q7MRM3
names: Similarity
messages: Belongs to the IMPACT family.

273121:WS RS01925
gene id: 273121:WS_RS01925
uniprot id: Q7MSJ4
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS09885
gene id: 273121:WS_RS09885
uniprot id: Q7M7T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

273121:WS RS06940
gene id: 273121:WS_RS06940
uniprot id: Q7M8S2
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

273121:WS RS00290
gene id: 273121:WS_RS00290
uniprot id: Q7MSW2
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

273121:WS RS08820
gene id: 273121:WS_RS08820
uniprot id: Q7M851
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

273121:WS RS08125
gene id: 273121:WS_RS08125
uniprot id: Q7MR47
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

273121:WS RS03815
gene id: 273121:WS_RS03815
uniprot id: Q7M9N4
names: Similarity
messages: Belongs to the HypE family.

273121:WS RS00485
gene id: 273121:WS_RS00485
uniprot id: Q7MAQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

273121:WS RS02320
gene id: 273121:WS_RS02320
uniprot id: Q7MA55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

273121:WS RS09100
gene id: 273121:WS_RS09100
uniprot id: Q7MQX0
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS01565
gene id: 273121:WS_RS01565
uniprot id: Q7MAD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

273121:WS RS01110
gene id: 273121:WS_RS01110
uniprot id: Q7MAI5
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

273121:WS RS02775
gene id: 273121:WS_RS02775
uniprot id: Q7M9Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

273121:WS RS05265
gene id: 273121:WS_RS05265
uniprot id: Q7MRR7
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

273121:WS RS04225
gene id: 273121:WS_RS04225
uniprot id: Q7M9J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

273121:WS RS09265
gene id: 273121:WS_RS09265
uniprot id: Q7M803
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

273121:WS RS05640
gene id: 273121:WS_RS05640
uniprot id: Q7MRN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

273121:WS RS01365
gene id: 273121:WS_RS01365
uniprot id: Q7MAG1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

273121:WS RS02515
gene id: 273121:WS_RS02515
uniprot id: Q7MSF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase B chain family.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Membrane

273121:WS RS02965
gene id: 273121:WS_RS02965
uniprot id: Q7M9X5
names: Similarity
messages: Belongs to the SAICAR synthetase family.

273121:WS RS04200
gene id: 273121:WS_RS04200
uniprot id: Q7M9J2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

273121:WS RS09175
gene id: 273121:WS_RS09175
uniprot id: Q7M811
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS08830
gene id: 273121:WS_RS08830
uniprot id: Q7MQZ4
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

273121:WS RS11265
gene id: 273121:WS_RS11265
uniprot id: Q7M7P7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

273121:WS RS01460
gene id: 273121:WS_RS01460
uniprot id: Q7MAE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

273121:WS RS08285
gene id: 273121:WS_RS08285
uniprot id: Q7M8B1
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

273121:WS RS04795
gene id: 273121:WS_RS04795
uniprot id: Q7MRW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

273121:WS RS05115
gene id: 273121:WS_RS05115
uniprot id: Q7M9A6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

273121:WS RS08790
gene id: 273121:WS_RS08790
uniprot id: P59933
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

273121:WS RS08825
gene id: 273121:WS_RS08825
uniprot id: Q7M850
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

273121:WS RS02110
gene id: 273121:WS_RS02110
uniprot id: Q7MA76
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

273121:WS RS01545
gene id: 273121:WS_RS01545
uniprot id: Q7MAD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

273121:WS RS09495
gene id: 273121:WS_RS09495
uniprot id: Q7MQU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

273121:WS RS08595
gene id: 273121:WS_RS08595
uniprot id: Q7M876
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

273121:WS RS07490
gene id: 273121:WS_RS07490
uniprot id: Q7M8L0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

273121:WS RS09895
gene id: 273121:WS_RS09895
uniprot id: Q7MQQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

273121:WS RS06465
gene id: 273121:WS_RS06465
uniprot id: Q7M8W5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

273121:WS RS08300
gene id: 273121:WS_RS08300
uniprot id: Q7M8A9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

273121:WS RS02390
gene id: 273121:WS_RS02390
uniprot id: Q7MA41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

273121:WS RS01685
gene id: 273121:WS_RS01685
uniprot id: Q7MAC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

273121:WS RS04740
gene id: 273121:WS_RS04740
uniprot id: Q7M9E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

273121:WS RS10195
gene id: 273121:WS_RS10195
uniprot id: Q7M7P6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

273121:WS RS03140
gene id: 273121:WS_RS03140
uniprot id: Q7MSA0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

273121:WS RS08085
gene id: 273121:WS_RS08085
uniprot id: Q7M8D4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19 (By similarity).

273121:WS RS04095
gene id: 273121:WS_RS04095
uniprot id: Q7M9K3
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

273121:WS RS09290
gene id: 273121:WS_RS09290
uniprot id: Q7M800
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

273121:WS RS06810
gene id: 273121:WS_RS06810
uniprot id: Q7M8T2
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

273121:WS RS01020
gene id: 273121:WS_RS01020
uniprot id: Q7MSR3
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

273121:WS RS08755
gene id: 273121:WS_RS08755
uniprot id: Q7M856
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

273121:WS RS03960
gene id: 273121:WS_RS03960
uniprot id: Q7M9L7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

273121:WS RS08710
gene id: 273121:WS_RS08710
uniprot id: Q7M859
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

273121:WS RS04005
gene id: 273121:WS_RS04005
uniprot id: Q79HR5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

273121:WS RS09955
gene id: 273121:WS_RS09955
uniprot id: Q7M7S7
names: Similarity
messages: Belongs to the threonine synthase family.

273121:WS RS02820
gene id: 273121:WS_RS02820
uniprot id: Q7M9Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0323 family.
messages: Cell membrane

273121:WS RS06665
gene id: 273121:WS_RS06665
uniprot id: Q7MRF5
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.
messages: Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.

273121:WS RS03050
gene id: 273121:WS_RS03050
uniprot id: Q7M9W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

273121:WS RS08505
gene id: 273121:WS_RS08505
uniprot id: Q7M889
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

273121:WS RS08910
gene id: 273121:WS_RS08910
uniprot id: Q7M842
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

273121:WS RS01150
gene id: 273121:WS_RS01150
uniprot id: Q7MAI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

273121:WS RS08055
gene id: 273121:WS_RS08055
uniprot id: Q7M8E0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

273121:WS RS09140
gene id: 273121:WS_RS09140
uniprot id: Q7M815
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

273121:WS RS10130
gene id: 273121:WS_RS10130
uniprot id: Q7M7Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

273121:WS RS10035
gene id: 273121:WS_RS10035
uniprot id: Q7MQP3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

273121:WS RS10355
gene id: 273121:WS_RS10355
uniprot id: Q7M7N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Important for motility and virulence.
messages: Heteromer of FlaA and FlaB. FlaB is located proximal to the hook while the remainder of the filament is composed of the predominant FlaA.
messages: Secreted

273121:WS RS01885
gene id: 273121:WS_RS01885
uniprot id: Q7MAA0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

273121:WS RS02325
gene id: 273121:WS_RS02325
uniprot id: Q7MA54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

273121:WS RS02440
gene id: 273121:WS_RS02440
uniprot id: Q7MA34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

273121:WS RS10120
gene id: 273121:WS_RS10120
uniprot id: Q7M7Q7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273121:WS RS07170
gene id: 273121:WS_RS07170
uniprot id: Q7M8P2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

273121:WS RS01440
gene id: 273121:WS_RS01440
uniprot id: Q7MAF2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

273121:WS RS08295
gene id: 273121:WS_RS08295
uniprot id: Q7M8B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

273121:WS RS05160
gene id: 273121:WS_RS05160
uniprot id: Q7MRS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Important for motility and virulence.
messages: Heteromer of FlaA and FlaB. FlaB is located proximal to the hook while the remainder of the filament is composed of the predominant FlaA.
messages: Secreted

273121:WS RS08325
gene id: 273121:WS_RS08325
uniprot id: Q9ZEN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

273121:WS RS06515
gene id: 273121:WS_RS06515
uniprot id: Q7M8W2
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS07020
gene id: 273121:WS_RS07020
uniprot id: Q7M8R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

273121:WS RS01155
gene id: 273121:WS_RS01155
uniprot id: Q7MAI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

273121:WS RS02750
gene id: 273121:WS_RS02750
uniprot id: Q7M9Z7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

273121:WS RS02020
gene id: 273121:WS_RS02020
uniprot id: Q7MA87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

273121:WS RS01215
gene id: 273121:WS_RS01215
uniprot id: Q7MSP7
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

273121:WS RS02880
gene id: 273121:WS_RS02880
uniprot id: Q7MSC1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

273121:WS RS07270
gene id: 273121:WS_RS07270
uniprot id: Q7MRA4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

273121:WS RS07180
gene id: 273121:WS_RS07180
uniprot id: Q7M8P1
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

273121:WS RS09490
gene id: 273121:WS_RS09490
uniprot id: Q7MQU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

273121:WS RS06220
gene id: 273121:WS_RS06220
uniprot id: Q7MRJ3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

273121:WS RS02180
gene id: 273121:WS_RS02180
uniprot id: Q7MA67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

273121:WS RS07995
gene id: 273121:WS_RS07995
uniprot id: Q7M8F1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

273121:WS RS07380
gene id: 273121:WS_RS07380
uniprot id: Q7M8L9
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS10105
gene id: 273121:WS_RS10105
uniprot id: Q7M7Q8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

273121:WS RS04105
gene id: 273121:WS_RS04105
uniprot id: Q7MS24
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

273121:WS RS01015
gene id: 273121:WS_RS01015
uniprot id: Q7MAJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

273121:WS RS09145
gene id: 273121:WS_RS09145
uniprot id: Q7M814
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

273121:WS RS06090
gene id: 273121:WS_RS06090
uniprot id: Q7M911
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

273121:WS RS01720
gene id: 273121:WS_RS01720
uniprot id: Q7MAB8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

273121:WS RS03235
gene id: 273121:WS_RS03235
uniprot id: Q7M9U5
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

273121:WS RS08670
gene id: 273121:WS_RS08670
uniprot id: Q7M866
names: Similarity
messages: Belongs to the AOR/FOR family.

273121:WS RS02410
gene id: 273121:WS_RS02410
uniprot id: Q7MA37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

273121:WS RS05455
gene id: 273121:WS_RS05455
uniprot id: Q7MRQ2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

273121:WS RS10470
gene id: 273121:WS_RS10470
uniprot id: Q7M7L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

273121:WS RS00910
gene id: 273121:WS_RS00910
uniprot id: Q7MAK9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

273121:WS RS06010
gene id: 273121:WS_RS06010
uniprot id: Q7MRK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

273121:WS RS01530
gene id: 273121:WS_RS01530
uniprot id: Q7MAE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

273121:WS RS05550
gene id: 273121:WS_RS05550
uniprot id: Q7MRP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

273121:WS RS08025
gene id: 273121:WS_RS08025
uniprot id: Q7M8E5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

273121:WS RS02910
gene id: 273121:WS_RS02910
uniprot id: Q7M9Y2
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

273121:WS RS06285
gene id: 273121:WS_RS06285
uniprot id: Q7M8Y4
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

273121:WS RS01540
gene id: 273121:WS_RS01540
uniprot id: Q7MSM1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

273121:WS RS08070
gene id: 273121:WS_RS08070
uniprot id: Q7M8D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

273121:WS RS10440
gene id: 273121:WS_RS10440
uniprot id: Q7M7L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

273121:WS RS02405
gene id: 273121:WS_RS02405
uniprot id: Q7MA38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

273121:WS RS01305
gene id: 273121:WS_RS01305
uniprot id: Q7MSN8
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS00765
gene id: 273121:WS_RS00765
uniprot id: Q7MST4
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS05755
gene id: 273121:WS_RS05755
uniprot id: Q7M948
names: Similarity
messages: Belongs to the glutamate synthase family.

273121:WS RS02710
gene id: 273121:WS_RS02710
uniprot id: Q7MA02
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

273121:WS RS09280
gene id: 273121:WS_RS09280
uniprot id: Q7MQV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

273121:WS RS04745
gene id: 273121:WS_RS04745
uniprot id: Q7M9E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

273121:WS RS09740
gene id: 273121:WS_RS09740
uniprot id: Q7M7V3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

273121:WS RS02830
gene id: 273121:WS_RS02830
uniprot id: Q7MSC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

273121:WS RS02850
gene id: 273121:WS_RS02850
uniprot id: Q7M9Y7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

273121:WS RS03065
gene id: 273121:WS_RS03065
uniprot id: Q7M9W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

273121:WS RS03485
gene id: 273121:WS_RS03485
uniprot id: Q7MS66
names: Similarity
messages: Belongs to the nitroreductase family.

273121:WS RS02210
gene id: 273121:WS_RS02210
uniprot id: Q7MSG7
names: Similarity
messages: Belongs to the UPF0102 family.

273121:WS RS02315
gene id: 273121:WS_RS02315
uniprot id: Q7MA56
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Fusion of rpoB and rpoC occurs naturally in Helicobacter species and at least some Wolbachia; the protein has been artificially split in two in H.pylori. The split protein seems to function normally.
messages: In the C-terminal section; belongs to the RNA polymerase beta' chain family.
messages: In the N-terminal section; belongs to the RNA polymerase beta chain family.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta/beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

273121:WS RS10385
gene id: 273121:WS_RS10385
uniprot id: Q7MQL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Cell membrane

273121:WS RS08860
gene id: 273121:WS_RS08860
uniprot id: Q7M847
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

273121:WS RS09180
gene id: 273121:WS_RS09180
uniprot id: Q7MQW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

273121:WS RS00555
gene id: 273121:WS_RS00555
uniprot id: P31077
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NrfD family.
messages: Cell inner membrane
messages: Component of the phosphorylative electron transport system with polysulfide as the terminal acceptor.
messages: Could possibly serve as the membrane anchor of the enzyme.
messages: Functional polysulfide reductase is made up of three different (A, B, and C) subunits.

273121:WS RS03230
gene id: 273121:WS_RS03230
uniprot id: O34245
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Responsible for the transport of C4-dicarboxylates.

273121:WS RS06205
gene id: 273121:WS_RS06205
uniprot id: Q7M8Z5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

273121:WS RS09380
gene id: 273121:WS_RS09380
uniprot id: Q7M7Z1
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

273121:WS RS02740
gene id: 273121:WS_RS02740
uniprot id: Q7M9Z9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

273121:WS RS05155
gene id: 273121:WS_RS05155
uniprot id: Q7M998
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

273121:WS RS06335
gene id: 273121:WS_RS06335
uniprot id: Q7M8Y0
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

273121:WS RS00785
gene id: 273121:WS_RS00785
uniprot id: Q7MAM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

273121:WS RS03835
gene id: 273121:WS_RS03835
uniprot id: Q7M9N2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

273121:WS RS03470
gene id: 273121:WS_RS03470
uniprot id: Q7MS67
names: Similarity
messages: Belongs to the thioesterase PaaI family.

273121:WS RS06325
gene id: 273121:WS_RS06325
uniprot id: Q7M8Y1
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS02860
gene id: 273121:WS_RS02860
uniprot id: Q7M9Y6
names: Similarity
messages: Belongs to the TlyA family.

273121:WS RS03720
gene id: 273121:WS_RS03720
uniprot id: Q7MS48
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

273121:WS RS01095
gene id: 273121:WS_RS01095
uniprot id: Q7MAI8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

273121:WS RS03135
gene id: 273121:WS_RS03135
uniprot id: Q7M9V4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

273121:WS RS02935
gene id: 273121:WS_RS02935
uniprot id: Q7M9X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

273121:WS RS07850
gene id: 273121:WS_RS07850
uniprot id: Q7M8G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

273121:WS RS08645
gene id: 273121:WS_RS08645
uniprot id: Q7M871
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS02300
gene id: 273121:WS_RS02300
uniprot id: Q7MA59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

273121:WS RS03585
gene id: 273121:WS_RS03585
uniprot id: Q7M9R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

273121:WS RS07065
gene id: 273121:WS_RS07065
uniprot id: Q7M8Q6
names: Subcellular Location Annotation
messages: Cytoplasm

273121:WS RS05970
gene id: 273121:WS_RS05970
uniprot id: Q7M925
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

273121:WS RS03465
gene id: 273121:WS_RS03465
uniprot id: Q7M9S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

273121:WS RS04575
gene id: 273121:WS_RS04575
uniprot id: Q7M9F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

273121:WS RS04885
gene id: 273121:WS_RS04885
uniprot id: Q7M9C6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

273121:WS RS06620
gene id: 273121:WS_RS06620
uniprot id: Q7MRG1
names: Similarity
messages: Belongs to the NifX/NifY family.

273121:WS RS10450
gene id: 273121:WS_RS10450
uniprot id: Q7M7L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane

273121:WS RS04870
gene id: 273121:WS_RS04870
uniprot id: Q7M9C8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

273121:WS RS09010
gene id: 273121:WS_RS09010
uniprot id: Q7M829
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

273121:WS RS04330
gene id: 273121:WS_RS04330
uniprot id: Q7M9I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

273121:WS RS04050
gene id: 273121:WS_RS04050
uniprot id: Q7M9K8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

273121:WS RS02290
gene id: 273121:WS_RS02290
uniprot id: Q7MA61
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

273121:WS RS08100
gene id: 273121:WS_RS08100
uniprot id: Q7M8D3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

273121:WS RS06700
gene id: 273121:WS_RS06700
uniprot id: Q7MRF1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

273121:WS RS05980
gene id: 273121:WS_RS05980
uniprot id: Q7M923
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

273121:WS RS01455
gene id: 273121:WS_RS01455
uniprot id: Q7MAE9
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

273121:WS RS04890
gene id: 273121:WS_RS04890
uniprot id: Q7MRV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

273121:WS RS06690
gene id: 273121:WS_RS06690
uniprot id: Q7M8U5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

273121:WS RS03280
gene id: 273121:WS_RS03280
uniprot id: Q7MS83
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS09440
gene id: 273121:WS_RS09440
uniprot id: Q7M7Y0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

273121:WS RS00980
gene id: 273121:WS_RS00980
uniprot id: Q7MAK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

273121:WS RS01760
gene id: 273121:WS_RS01760
uniprot id: Q7MAB3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

273121:WS RS05985
gene id: 273121:WS_RS05985
uniprot id: Q7M922
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

273121:WS RS07555
gene id: 273121:WS_RS07555
uniprot id: Q7M8K4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

273121:WS RS02090
gene id: 273121:WS_RS02090
uniprot id: Q7MA77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

273121:WS RS09875
gene id: 273121:WS_RS09875
uniprot id: Q7M7T6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

273121:WS RS06705
gene id: 273121:WS_RS06705
uniprot id: Q7M8U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

273121:WS RS10145
gene id: 273121:WS_RS10145
uniprot id: Q7M7Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

273121:WS RS07260
gene id: 273121:WS_RS07260
uniprot id: Q7MRA5
names: Similarity
messages: Belongs to the CvfB family.

273121:WS RS03075
gene id: 273121:WS_RS03075
uniprot id: Q7M9W1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

273121:WS RS00035
gene id: 273121:WS_RS00035
uniprot id: Q7MAU9
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS07970
gene id: 273121:WS_RS07970
uniprot id: Q7M8F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

273121:WS RS08780
gene id: 273121:WS_RS08780
uniprot id: Q7M853
names: Similarity
messages: Belongs to the NadC/ModD family.

273121:WS RS00815
gene id: 273121:WS_RS00815
uniprot id: Q7MAL6
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

273121:WS RS00445
gene id: 273121:WS_RS00445
uniprot id: Q7MAQ6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

273121:WS RS07030
gene id: 273121:WS_RS07030
uniprot id: Q7M8R1
names: Similarity
messages: Belongs to the peptidase S49 family.

273121:WS RS03385
gene id: 273121:WS_RS03385
uniprot id: Q7M9T3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

273121:WS RS04185
gene id: 273121:WS_RS04185
uniprot id: Q7M9J5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

273121:WS RS02790
gene id: 273121:WS_RS02790
uniprot id: Q7M9Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

273121:WS RS06800
gene id: 273121:WS_RS06800
uniprot id: Q7M8T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

273121:WS RS03860
gene id: 273121:WS_RS03860
uniprot id: Q7M9N0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

273121:WS RS00970
gene id: 273121:WS_RS00970
uniprot id: Q7MAK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

273121:WS RS08015
gene id: 273121:WS_RS08015
uniprot id: Q7M8E7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

273121:WS RS02050
gene id: 273121:WS_RS02050
uniprot id: Q7MA83
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

273121:WS RS04585
gene id: 273121:WS_RS04585
uniprot id: Q7M9F5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

273121:WS RS07590
gene id: 273121:WS_RS07590
uniprot id: Q7M8J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

273121:WS RS08650
gene id: 273121:WS_RS08650
uniprot id: Q7M870
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS09600
gene id: 273121:WS_RS09600
uniprot id: Q7M7X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

273121:WS RS01125
gene id: 273121:WS_RS01125
uniprot id: Q7MAI2
names: Similarity
messages: Belongs to the RecJ family.

273121:WS RS03100
gene id: 273121:WS_RS03100
uniprot id: Q7M9V8
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS05645
gene id: 273121:WS_RS05645
uniprot id: Q7MRN3
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS05250
gene id: 273121:WS_RS05250
uniprot id: Q7MRS0
names: Similarity
messages: Belongs to the GSP E family.

273121:WS RS08655
gene id: 273121:WS_RS08655
uniprot id: Q7M869
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS09165
gene id: 273121:WS_RS09165
uniprot id: Q7M813
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

273121:WS RS06600
gene id: 273121:WS_RS06600
uniprot id: Q7M8V0
names: Similarity
messages: Belongs to the NifZ family.

273121:WS RS09595
gene id: 273121:WS_RS09595
uniprot id: Q7M7X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

273121:WS RS07465
gene id: 273121:WS_RS07465
uniprot id: Q7M8L1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

273121:WS RS08050
gene id: 273121:WS_RS08050
uniprot id: Q7M8E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

273121:WS RS06580
gene id: 273121:WS_RS06580
uniprot id: Q7M8V2
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS10380
gene id: 273121:WS_RS10380
uniprot id: Q7M7M8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

273121:WS RS08925
gene id: 273121:WS_RS08925
uniprot id: Q7M839
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

273121:WS RS10125
gene id: 273121:WS_RS10125
uniprot id: Q7M7Q6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks the conserved Asp active site.

273121:WS RS00330
gene id: 273121:WS_RS00330
uniprot id: Q7MSV6
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS03820
gene id: 273121:WS_RS03820
uniprot id: Q7MS42
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

273121:WS RS02455
gene id: 273121:WS_RS02455
uniprot id: Q7MA33
names: Function
names: Subunit
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Important for motility and virulence.
messages: Heteromer of FlaA and FlaB. FlaB is located proximal to the hook while the remainder of the filament is composed of the predominant FlaA.

273121:WS RS03170
gene id: 273121:WS_RS03170
uniprot id: Q7MS97
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS01380
gene id: 273121:WS_RS01380
uniprot id: Q7MAF8
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS02550
gene id: 273121:WS_RS02550
uniprot id: Q7MA18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

273121:WS RS06070
gene id: 273121:WS_RS06070
uniprot id: Q7M915
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Probably functions as a manganese efflux pump.

273121:WS RS08935
gene id: 273121:WS_RS08935
uniprot id: Q7M838
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

273121:WS RS01435
gene id: 273121:WS_RS01435
uniprot id: Q7MAF3
names: Similarity
messages: Belongs to the MotB family.

273121:WS RS07120
gene id: 273121:WS_RS07120
uniprot id: Q7M8P9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

273121:WS RS03495
gene id: 273121:WS_RS03495
uniprot id: Q7M9R9
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS00850
gene id: 273121:WS_RS00850
uniprot id: Q7MSS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

273121:WS RS08410
gene id: 273121:WS_RS08410
uniprot id: Q7MR21
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS03580
gene id: 273121:WS_RS03580
uniprot id: Q7M9R1
names: Similarity
messages: Belongs to the Nth/MutY family.

273121:WS RS07960
gene id: 273121:WS_RS07960
uniprot id: Q7M8F8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

273121:WS RS02685
gene id: 273121:WS_RS02685
uniprot id: Q7MSD9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

273121:WS RS04660
gene id: 273121:WS_RS04660
uniprot id: Q9S1E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: In the C-terminal section; belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: May play a role in cytochrome c biogenesis and may be required for maturation of the NrfA protein.

273121:WS RS00530
gene id: 273121:WS_RS00530
uniprot id: Q7MAP3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

273121:WS RS00140
gene id: 273121:WS_RS00140
uniprot id: Q4KKT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

273121:WS RS04370
gene id: 273121:WS_RS04370
uniprot id: Q7M9H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

273121:WS RS05975
gene id: 273121:WS_RS05975
uniprot id: Q7M924
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

273121:WS RS10565
gene id: 273121:WS_RS10565
uniprot id: Q7MS51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

273121:WS RS04860
gene id: 273121:WS_RS04860
uniprot id: Q7M9C9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

273121:WS RS03390
gene id: 273121:WS_RS03390
uniprot id: Q7M9T2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

273121:WS RS06015
gene id: 273121:WS_RS06015
uniprot id: Q7M919
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

273121:WS RS04355
gene id: 273121:WS_RS04355
uniprot id: Q7M9H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

273121:WS RS07915
gene id: 273121:WS_RS07915
uniprot id: O34246
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

273121:WS RS07735
gene id: 273121:WS_RS07735
uniprot id: Q7M8I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

273121:WS RS02215
gene id: 273121:WS_RS02215
uniprot id: Q7MSG6
names: Similarity
messages: Belongs to the thioredoxin family.

273121:WS RS08255
gene id: 273121:WS_RS08255
uniprot id: Q7M8B4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

273121:WS RS07145
gene id: 273121:WS_RS07145
uniprot id: Q79HP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Important for motility and virulence.
messages: Heteromer of FlaA and FlaB. FlaB is located proximal to the hook while the remainder of the filament is composed of the predominant FlaA.
messages: Secreted

273121:WS RS05815
gene id: 273121:WS_RS05815
uniprot id: Q7M939
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

273121:WS RS00625
gene id: 273121:WS_RS00625
uniprot id: Q7MAN5
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS02605
gene id: 273121:WS_RS02605
uniprot id: Q7MSE9
names: Similarity
messages: Belongs to the GSP E family.

273121:WS RS01045
gene id: 273121:WS_RS01045
uniprot id: Q7MAJ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

273121:WS RS07135
gene id: 273121:WS_RS07135
uniprot id: Q7M8P7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

273121:WS RS06795
gene id: 273121:WS_RS06795
uniprot id: Q7M8T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

273121:WS RS07840
gene id: 273121:WS_RS07840
uniprot id: Q7M8H0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

273121:WS RS09115
gene id: 273121:WS_RS09115
uniprot id: Q7M819
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273121:WS RS02475
gene id: 273121:WS_RS02475
uniprot id: Q7MA30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

273121:WS RS06055
gene id: 273121:WS_RS06055
uniprot id: Q7M917
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS08250
gene id: 273121:WS_RS08250
uniprot id: Q7M8B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

273121:WS RS06895
gene id: 273121:WS_RS06895
uniprot id: Q7MRD3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Monomer. Binds crRNA and tracrRNA.

273121:WS RS05605
gene id: 273121:WS_RS05605
uniprot id: Q79HQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

273121:WS RS09130
gene id: 273121:WS_RS09130
uniprot id: Q7M817
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

273121:WS RS07335
gene id: 273121:WS_RS07335
uniprot id: Q7M8M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PhnC), two transmembrane proteins (PhnE) and a solute-binding protein (PhnD).

273121:WS RS08515
gene id: 273121:WS_RS08515
uniprot id: Q7M887
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

273121:WS RS01835
gene id: 273121:WS_RS01835
uniprot id: Q7MAA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

273121:WS RS05045
gene id: 273121:WS_RS05045
uniprot id: Q7M9B2
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

273121:WS RS10480
gene id: 273121:WS_RS10480
uniprot id: Q7MQL0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

273121:WS RS05745
gene id: 273121:WS_RS05745
uniprot id: Q7M950
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

273121:WS RS09410
gene id: 273121:WS_RS09410
uniprot id: Q7MQU6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

273121:WS RS04685
gene id: 273121:WS_RS04685
uniprot id: Q7MRX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Probably functions as a manganese efflux pump.

273121:WS RS01840
gene id: 273121:WS_RS01840
uniprot id: Q7MSK1
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS09815
gene id: 273121:WS_RS09815
uniprot id: Q7M7U5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

273121:WS RS05500
gene id: 273121:WS_RS05500
uniprot id: Q4KKT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

273121:WS RS01810
gene id: 273121:WS_RS01810
uniprot id: Q7MAA9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

273121:WS RS06765
gene id: 273121:WS_RS06765
uniprot id: Q7M8T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

273121:WS RS08020
gene id: 273121:WS_RS08020
uniprot id: Q7M8E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

273121:WS RS01800
gene id: 273121:WS_RS01800
uniprot id: Q7MAB0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

273121:WS RS00695
gene id: 273121:WS_RS00695
uniprot id: Q7MSU1
names: Similarity
messages: Belongs to the LarC family.

273121:WS RS10455
gene id: 273121:WS_RS10455
uniprot id: Q7M7L7
names: Similarity
messages: Belongs to the peptidase M16 family.

273121:WS RS03550
gene id: 273121:WS_RS03550
uniprot id: Q7M9R5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

273121:WS RS10510
gene id: 273121:WS_RS10510
uniprot id: Q7MAU5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Membrane

273121:WS RS05120
gene id: 273121:WS_RS05120
uniprot id: Q7M9A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

273121:WS RS08460
gene id: 273121:WS_RS08460
uniprot id: Q7M896
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

273121:WS RS07965
gene id: 273121:WS_RS07965
uniprot id: Q7M8F7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta/beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription (By similarity).
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

273121:WS RS02060
gene id: 273121:WS_RS02060
uniprot id: Q7MA81
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

273121:WS RS00470
gene id: 273121:WS_RS00470
uniprot id: Q7MAQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

273121:WS RS07755
gene id: 273121:WS_RS07755
uniprot id: Q7M8I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

273121:WS RS04335
gene id: 273121:WS_RS04335
uniprot id: Q7M9H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

273121:WS RS06060
gene id: 273121:WS_RS06060
uniprot id: Q7MRK1
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS08030
gene id: 273121:WS_RS08030
uniprot id: Q7M8E4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

273121:WS RS07715
gene id: 273121:WS_RS07715
uniprot id: Q7M8I7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

273121:WS RS09660
gene id: 273121:WS_RS09660
uniprot id: Q7M7W0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

273121:WS RS07935
gene id: 273121:WS_RS07935
uniprot id: P31883
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Binds 1 nickel ion per subunit.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.
messages: This enzyme recycles the H(2) produced by nitrogenase to increase the production of ATP and to protect nitrogenase against inhibition or damage by O(2) under carbon- or phosphate-limited conditions.

273121:WS RS04665
gene id: 273121:WS_RS04665
uniprot id: Q9S1E5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c-552 family.
messages: Binds 1 Ca(2+) ion per monomer.
messages: Binds 5 heme c groups covalently per monomer.
messages: Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process. Has very low activity toward hydroxylamine, and even lower activity toward sulfite. Sulfite reductase activity is maximal at neutral pH.
messages: Homodimer (PubMed:10984487, PubMed:12296741). Interacts with NrfH (PubMed:10672190). May form a heterotetramer with NrfH (PubMed:11807271).
messages: Periplasm

273121:WS RS03925
gene id: 273121:WS_RS03925
uniprot id: Q7M9M3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

273121:WS RS09690
gene id: 273121:WS_RS09690
uniprot id: Q7MQS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

273121:WS RS01515
gene id: 273121:WS_RS01515
uniprot id: Q7MAE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

273121:WS RS07780
gene id: 273121:WS_RS07780
uniprot id: Q7MR59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

273121:WS RS06915
gene id: 273121:WS_RS06915
uniprot id: Q7M8S6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

273121:WS RS08420
gene id: 273121:WS_RS08420
uniprot id: Q7M8A0
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

273121:WS RS08705
gene id: 273121:WS_RS08705
uniprot id: Q7M860
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

273121:WS RS09755
gene id: 273121:WS_RS09755
uniprot id: Q7MQR4
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

273121:WS RS00725
gene id: 273121:WS_RS00725
uniprot id: Q7MST9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

273121:WS RS09610
gene id: 273121:WS_RS09610
uniprot id: Q7M7W8
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

273121:WS RS02680
gene id: 273121:WS_RS02680
uniprot id: Q7MA06
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

273121:WS RS08855
gene id: 273121:WS_RS08855
uniprot id: Q7M848
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

273121:WS RS02155
gene id: 273121:WS_RS02155
uniprot id: Q7MA70
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

273121:WS RS10590
gene id: 273121:WS_RS10590
uniprot id: Q7MS10
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

273121:WS RS02480
gene id: 273121:WS_RS02480
uniprot id: Q7MA29
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

273121:WS RS10495
gene id: 273121:WS_RS10495
uniprot id: Q7MQK8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

273121:WS RS07250
gene id: 273121:WS_RS07250
uniprot id: Q7M8N4
names: Similarity
messages: Belongs to the class-I fumarase family.

273121:WS RS07535
gene id: 273121:WS_RS07535
uniprot id: Q7MR79
names: Similarity
messages: Belongs to the peptidase S51 family.

273121:WS RS01745
gene id: 273121:WS_RS01745
uniprot id: Q7MSK9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

273121:WS RS08435
gene id: 273121:WS_RS08435
uniprot id: Q7MR19
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

273121:WS RS05165
gene id: 273121:WS_RS05165
uniprot id: Q7M997
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

273121:WS RS10500
gene id: 273121:WS_RS10500
uniprot id: Q7M7L1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

273121:WS RS10170
gene id: 273121:WS_RS10170
uniprot id: Q7M7P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

273121:WS RS08585
gene id: 273121:WS_RS08585
uniprot id: Q7M878
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

273121:WS RS08010
gene id: 273121:WS_RS08010
uniprot id: Q7M8E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

273121:WS RS08900
gene id: 273121:WS_RS08900
uniprot id: Q7M844
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

273121:WS RS03965
gene id: 273121:WS_RS03965
uniprot id: Q7M9L6
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

273121:WS RS07980
gene id: 273121:WS_RS07980
uniprot id: Q7M8F4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

273121:WS RS09795
gene id: 273121:WS_RS09795
uniprot id: Q7MQR0
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS00355
gene id: 273121:WS_RS00355
uniprot id: Q7MAR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

273121:WS RS07105
gene id: 273121:WS_RS07105
uniprot id: Q7M8Q0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

273121:WS RS05090
gene id: 273121:WS_RS05090
uniprot id: Q7M9A8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

273121:WS RS05835
gene id: 273121:WS_RS05835
uniprot id: Q7M937
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family. XerH subfamily.
messages: Cytoplasm
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

273121:WS RS02620
gene id: 273121:WS_RS02620
uniprot id: Q7MA11
names: Similarity
messages: Belongs to the GSP E family.

273121:WS RS02525
gene id: 273121:WS_RS02525
uniprot id: Q7MA21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

273121:WS RS09480
gene id: 273121:WS_RS09480
uniprot id: Q7M7X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

273121:WS RS08225
gene id: 273121:WS_RS08225
uniprot id: Q7MR39
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

273121:WS RS04940
gene id: 273121:WS_RS04940
uniprot id: Q7M9C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

273121:WS RS00780
gene id: 273121:WS_RS00780
uniprot id: Q7MST2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

273121:WS RS00025
gene id: 273121:WS_RS00025
uniprot id: Q7MAV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

273121:WS RS05870
gene id: 273121:WS_RS05870
uniprot id: Q7M932
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

273121:WS RS00145
gene id: 273121:WS_RS00145
uniprot id: P27273
names: Cofactor
names: Function
names: Subunit
messages: Binds 4 [4Fe-4S] clusters.
messages: Formate dehydrogenase is a membrane-bound complex, formed of at least three different subunits.
messages: This chain is an electron transfer unit containing 18 cysteine residues, 16 of which occur in four clusters.

273121:WS RS02705
gene id: 273121:WS_RS02705
uniprot id: Q7MA03
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

273121:WS RS00640
gene id: 273121:WS_RS00640
uniprot id: Q7MAN2
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

273121:WS RS04170
gene id: 273121:WS_RS04170
uniprot id: Q7M9J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

273121:WS RS06785
gene id: 273121:WS_RS06785
uniprot id: Q7M8T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

273121:WS RS08845
gene id: 273121:WS_RS08845
uniprot id: Q7MQZ2
names: Similarity
messages: Belongs to the DprA/Smf family.

273121:WS RS02175
gene id: 273121:WS_RS02175
uniprot id: Q7MSH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

273121:WS RS08785
gene id: 273121:WS_RS08785
uniprot id: Q7MQZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

273121:WS RS01025
gene id: 273121:WS_RS01025
uniprot id: Q7MAJ6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

273121:WS RS00950
gene id: 273121:WS_RS00950
uniprot id: Q7MSR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

273121:WS RS10410
gene id: 273121:WS_RS10410
uniprot id: Q7M7M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

273121:WS RS06065
gene id: 273121:WS_RS06065
uniprot id: Q7M916
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS09350
gene id: 273121:WS_RS09350
uniprot id: Q7M7Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

273121:WS RS01445
gene id: 273121:WS_RS01445
uniprot id: Q7MAF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

273121:WS RS07080
gene id: 273121:WS_RS07080
uniprot id: Q7M8Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

273121:WS RS00015
gene id: 273121:WS_RS00015
uniprot id: Q7MAV1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

273121:WS RS01490
gene id: 273121:WS_RS01490
uniprot id: Q7MSM4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

273121:WS RS04160
gene id: 273121:WS_RS04160
uniprot id: Q7M9J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

273121:WS RS06265
gene id: 273121:WS_RS06265
uniprot id: Q7M8Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

273121:WS RS05015
gene id: 273121:WS_RS05015
uniprot id: Q7MRU0
names: Similarity
messages: Belongs to the CutA family.

273121:WS RS01170
gene id: 273121:WS_RS01170
uniprot id: Q7MSQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

273121:WS RS04440
gene id: 273121:WS_RS04440
uniprot id: Q7MRZ1
names: Subcellular Location Annotation
messages: Membrane

273121:WS RS06150
gene id: 273121:WS_RS06150
uniprot id: Q7M901
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

273121:WS RS09270
gene id: 273121:WS_RS09270
uniprot id: Q7M802
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

273121:WS RS08475
gene id: 273121:WS_RS08475
uniprot id: Q7M893
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

273121:WS RS07245
gene id: 273121:WS_RS07245
uniprot id: Q7M8N5
names: Similarity
messages: Belongs to the class-I fumarase family.

273121:WS RS01910
gene id: 273121:WS_RS01910
uniprot id: Q7MSJ7
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

273121:WS RS04830
gene id: 273121:WS_RS04830
uniprot id: Q7MRV9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

273121:WS RS07790
gene id: 273121:WS_RS07790
uniprot id: Q7M8H6
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

273121:WS RS05025
gene id: 273121:WS_RS05025
uniprot id: Q7MRT9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Homodimer.

273121:WS RS07975
gene id: 273121:WS_RS07975
uniprot id: Q7M8F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

273121:WS RS02735
gene id: 273121:WS_RS02735
uniprot id: Q7MSD5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

273121:WS RS01680
gene id: 273121:WS_RS01680
uniprot id: Q7MAC5
names: Similarity
messages: Belongs to the ClpA/ClpB family.