2710756:G4Z16 RS21510
gene id: 2710756:G4Z16_RS21510
uniprot id: A0A7T1WRX1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2710756:G4Z16 RS24455
gene id: 2710756:G4Z16_RS24455
uniprot id: A0A7T1T9S9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2710756:G4Z16 RS08210
gene id: 2710756:G4Z16_RS08210
uniprot id: A0A7T1TCN6
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

2710756:G4Z16 RS24060
gene id: 2710756:G4Z16_RS24060
uniprot id: A0A7T1T9P6
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

2710756:G4Z16 RS12180
gene id: 2710756:G4Z16_RS12180
uniprot id: A0A7T1T5Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2710756:G4Z16 RS17775
gene id: 2710756:G4Z16_RS17775
uniprot id: A0A7T1T7Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2710756:G4Z16 RS09160
gene id: 2710756:G4Z16_RS09160
uniprot id: A0A7T1T544
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2710756:G4Z16 RS12100
gene id: 2710756:G4Z16_RS12100
uniprot id: A0A7T1T5Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2710756:G4Z16 RS13970
gene id: 2710756:G4Z16_RS13970
uniprot id: A0A7T1T6L0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

2710756:G4Z16 RS10075
gene id: 2710756:G4Z16_RS10075
uniprot id: A0A7T1WRM9
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

2710756:G4Z16 RS07885
gene id: 2710756:G4Z16_RS07885
uniprot id: A0A7T1T4S9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2710756:G4Z16 RS22490
gene id: 2710756:G4Z16_RS22490
uniprot id: A0A7T1WS22
names: Similarity
messages: Belongs to the universal stress protein A family.

2710756:G4Z16 RS13560
gene id: 2710756:G4Z16_RS13560
uniprot id: A0A7T1T6C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

2710756:G4Z16 RS08040
gene id: 2710756:G4Z16_RS08040
uniprot id: A0A7T1T4Q4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2710756:G4Z16 RS28800
gene id: 2710756:G4Z16_RS28800
uniprot id: A0A7T1WV05
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2710756:G4Z16 RS11865
gene id: 2710756:G4Z16_RS11865
uniprot id: A0A7T1T5U6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

2710756:G4Z16 RS21875
gene id: 2710756:G4Z16_RS21875
uniprot id: A0A7T1WTH4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2710756:G4Z16 RS08015
gene id: 2710756:G4Z16_RS08015
uniprot id: A0A7T1WT17
names: Similarity
messages: Belongs to the acylphosphatase family.

2710756:G4Z16 RS10370
gene id: 2710756:G4Z16_RS10370
uniprot id: A0A7T1WRP5
names: Similarity
messages: Belongs to the LOG family.

2710756:G4Z16 RS00155
gene id: 2710756:G4Z16_RS00155
uniprot id: A0A7T1T291
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

2710756:G4Z16 RS10395
gene id: 2710756:G4Z16_RS10395
uniprot id: A0A7T1T5E9
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2710756:G4Z16 RS12185
gene id: 2710756:G4Z16_RS12185
uniprot id: A0A7T1T5Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2710756:G4Z16 RS12320
gene id: 2710756:G4Z16_RS12320
uniprot id: A0A7T1WTP7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2710756:G4Z16 RS25900
gene id: 2710756:G4Z16_RS25900
uniprot id: A0A7T1WSK9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

2710756:G4Z16 RS12110
gene id: 2710756:G4Z16_RS12110
uniprot id: A0A7T1T616
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2710756:G4Z16 RS12650
gene id: 2710756:G4Z16_RS12650
uniprot id: A0A7T1T646
names: Subcellular Location Annotation
messages: Cytoplasm

2710756:G4Z16 RS09200
gene id: 2710756:G4Z16_RS09200
uniprot id: A0A7T1WQ86
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2710756:G4Z16 RS12130
gene id: 2710756:G4Z16_RS12130
uniprot id: A0A7T1T617
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2710756:G4Z16 RS05920
gene id: 2710756:G4Z16_RS05920
uniprot id: A0A7T1T423
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2710756:G4Z16 RS10640
gene id: 2710756:G4Z16_RS10640
uniprot id: A0A7T1WQE0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2710756:G4Z16 RS08190
gene id: 2710756:G4Z16_RS08190
uniprot id: A0A7T1T4S6
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

2710756:G4Z16 RS12105
gene id: 2710756:G4Z16_RS12105
uniprot id: A0A7T1TCV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2710756:G4Z16 RS11965
gene id: 2710756:G4Z16_RS11965
uniprot id: A0A7T1T623
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2710756:G4Z16 RS28765
gene id: 2710756:G4Z16_RS28765
uniprot id: A0A7T1TB92
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

2710756:G4Z16 RS23415
gene id: 2710756:G4Z16_RS23415
uniprot id: A0A7T1TDE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

2710756:G4Z16 RS26090
gene id: 2710756:G4Z16_RS26090
uniprot id: A0A7T1WU60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

2710756:G4Z16 RS30675
gene id: 2710756:G4Z16_RS30675
uniprot id: A0A7T1WTB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

2710756:G4Z16 RS28750
gene id: 2710756:G4Z16_RS28750
uniprot id: A0A7T1TDU0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2710756:G4Z16 RS16205
gene id: 2710756:G4Z16_RS16205
uniprot id: A0A7T1WUA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

2710756:G4Z16 RS23785
gene id: 2710756:G4Z16_RS23785
uniprot id: A0A7T1T9Q5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

2710756:G4Z16 RS26565
gene id: 2710756:G4Z16_RS26565
uniprot id: A0A7T1WU86
names: Similarity
messages: Belongs to the TrpC family.

2710756:G4Z16 RS27480
gene id: 2710756:G4Z16_RS27480
uniprot id: A0A7T1WUE0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

2710756:G4Z16 RS07435
gene id: 2710756:G4Z16_RS07435
uniprot id: A0A7T1T4J1
names: Similarity
messages: Belongs to the WXG100 family.

2710756:G4Z16 RS12550
gene id: 2710756:G4Z16_RS12550
uniprot id: A0A7T1T634
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2710756:G4Z16 RS12075
gene id: 2710756:G4Z16_RS12075
uniprot id: A0A7T1WSD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2710756:G4Z16 RS00135
gene id: 2710756:G4Z16_RS00135
uniprot id: A0A7T1T2B7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2710756:G4Z16 RS07905
gene id: 2710756:G4Z16_RS07905
uniprot id: A0A7T1WRB6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

2710756:G4Z16 RS12090
gene id: 2710756:G4Z16_RS12090
uniprot id: A0A7T1T602
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2710756:G4Z16 RS27830
gene id: 2710756:G4Z16_RS27830
uniprot id: A0A7T1TAU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

2710756:G4Z16 RS17745
gene id: 2710756:G4Z16_RS17745
uniprot id: A0A7T1T7R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

2710756:G4Z16 RS18255
gene id: 2710756:G4Z16_RS18255
uniprot id: A0A7T1T7W5
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

2710756:G4Z16 RS12065
gene id: 2710756:G4Z16_RS12065
uniprot id: A0A7T1WTN4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2710756:G4Z16 RS07815
gene id: 2710756:G4Z16_RS07815
uniprot id: A0A7T1WQ41
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2710756:G4Z16 RS19190
gene id: 2710756:G4Z16_RS19190
uniprot id: A0A7T1T867
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

2710756:G4Z16 RS19185
gene id: 2710756:G4Z16_RS19185
uniprot id: A0A7T1T856
names: Subcellular Location Annotation
messages: Cytoplasm

2710756:G4Z16 RS22140
gene id: 2710756:G4Z16_RS22140
uniprot id: A0A7T1WV68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

2710756:G4Z16 RS11885
gene id: 2710756:G4Z16_RS11885
uniprot id: A0A7T1T5Z4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

2710756:G4Z16 RS07810
gene id: 2710756:G4Z16_RS07810
uniprot id: A0A7T1T4M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

2710756:G4Z16 RS23115
gene id: 2710756:G4Z16_RS23115
uniprot id: A0A7T1WTP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

2710756:G4Z16 RS29545
gene id: 2710756:G4Z16_RS29545
uniprot id: A0A7T1WV52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2710756:G4Z16 RS12080
gene id: 2710756:G4Z16_RS12080
uniprot id: A0A7T1T5X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2710756:G4Z16 RS26240
gene id: 2710756:G4Z16_RS26240
uniprot id: A0A7T1WVT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

2710756:G4Z16 RS12030
gene id: 2710756:G4Z16_RS12030
uniprot id: A0A7T1T5W9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2710756:G4Z16 RS29820
gene id: 2710756:G4Z16_RS29820
uniprot id: A0A7T1TBH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

2710756:G4Z16 RS08615
gene id: 2710756:G4Z16_RS08615
uniprot id: A0A7T1TCP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2710756:G4Z16 RS21095
gene id: 2710756:G4Z16_RS21095
uniprot id: A0A7T1T8R5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

2710756:G4Z16 RS20415
gene id: 2710756:G4Z16_RS20415
uniprot id: A0A7T1WUX3
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

2710756:G4Z16 RS12205
gene id: 2710756:G4Z16_RS12205
uniprot id: A0A7T1T5Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2710756:G4Z16 RS08345
gene id: 2710756:G4Z16_RS08345
uniprot id: A0A7T1T4T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

2710756:G4Z16 RS21865
gene id: 2710756:G4Z16_RS21865
uniprot id: A0A7T1WTI1
names: Subcellular Location Annotation
messages: Cytoplasm

2710756:G4Z16 RS09055
gene id: 2710756:G4Z16_RS09055
uniprot id: A0A7T1T507
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

2710756:G4Z16 RS12225
gene id: 2710756:G4Z16_RS12225
uniprot id: A0A7T1WQK9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2710756:G4Z16 RS16215
gene id: 2710756:G4Z16_RS16215
uniprot id: A0A7T1WT02
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2710756:G4Z16 RS12095
gene id: 2710756:G4Z16_RS12095
uniprot id: A0A7T1T5X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2710756:G4Z16 RS09920
gene id: 2710756:G4Z16_RS09920
uniprot id: A0A7T1T5B4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2710756:G4Z16 RS12055
gene id: 2710756:G4Z16_RS12055
uniprot id: A0A7T1T611
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

2710756:G4Z16 RS22720
gene id: 2710756:G4Z16_RS22720
uniprot id: A0A7T1T9A1
names: Subcellular Location Annotation
messages: Membrane

2710756:G4Z16 RS26970
gene id: 2710756:G4Z16_RS26970
uniprot id: A0A7T1WUA9
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

2710756:G4Z16 RS10955
gene id: 2710756:G4Z16_RS10955
uniprot id: A0A7T1WS59
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

2710756:G4Z16 RS12015
gene id: 2710756:G4Z16_RS12015
uniprot id: A0A7T1T5Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2710756:G4Z16 RS25135
gene id: 2710756:G4Z16_RS25135
uniprot id: A0A7T1T9Z3
names: Similarity
messages: Belongs to the glutamine synthetase family.

2710756:G4Z16 RS21765
gene id: 2710756:G4Z16_RS21765
uniprot id: A0A7T1T8Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

2710756:G4Z16 RS26285
gene id: 2710756:G4Z16_RS26285
uniprot id: A0A7T1WU70
names: Similarity
messages: Belongs to the YggT family.

2710756:G4Z16 RS19940
gene id: 2710756:G4Z16_RS19940
uniprot id: A0A7T1T8E3
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

2710756:G4Z16 RS27540
gene id: 2710756:G4Z16_RS27540
uniprot id: A0A7T1TAS1
names: Subcellular Location Annotation
messages: Membrane

2710756:G4Z16 RS11990
gene id: 2710756:G4Z16_RS11990
uniprot id: A0A7T1WRX3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2710756:G4Z16 RS05590
gene id: 2710756:G4Z16_RS05590
uniprot id: A0A7T1T3Y2
names: Subcellular Location Annotation
messages: Cytoplasm

2710756:G4Z16 RS08470
gene id: 2710756:G4Z16_RS08470
uniprot id: A0A7T1T4U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

2710756:G4Z16 RS17445
gene id: 2710756:G4Z16_RS17445
uniprot id: A0A7T1T7Q3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

2710756:G4Z16 RS11870
gene id: 2710756:G4Z16_RS11870
uniprot id: A0A7T1WVF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2710756:G4Z16 RS12600
gene id: 2710756:G4Z16_RS12600
uniprot id: A0A7T1T695
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2710756:G4Z16 RS02660
gene id: 2710756:G4Z16_RS02660
uniprot id: A0A7T1WQX6
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

2710756:G4Z16 RS29245
gene id: 2710756:G4Z16_RS29245
uniprot id: A0A7T1WT33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

2710756:G4Z16 RS14100
gene id: 2710756:G4Z16_RS14100
uniprot id: A0A7T1WQV8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2710756:G4Z16 RS12595
gene id: 2710756:G4Z16_RS12595
uniprot id: A0A7T1T635
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2710756:G4Z16 RS12045
gene id: 2710756:G4Z16_RS12045
uniprot id: A0A7T1T631
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2710756:G4Z16 RS08420
gene id: 2710756:G4Z16_RS08420
uniprot id: A0A7T1WRR4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

2710756:G4Z16 RS23425
gene id: 2710756:G4Z16_RS23425
uniprot id: A0A7T1T9H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

2710756:G4Z16 RS12010
gene id: 2710756:G4Z16_RS12010
uniprot id: A0A7T1T5V6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2710756:G4Z16 RS07360
gene id: 2710756:G4Z16_RS07360
uniprot id: A0A7T1T4J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2710756:G4Z16 RS26990
gene id: 2710756:G4Z16_RS26990
uniprot id: A0A7T1TAL1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2710756:G4Z16 RS12000
gene id: 2710756:G4Z16_RS12000
uniprot id: A0A7T1WRZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2710756:G4Z16 RS11935
gene id: 2710756:G4Z16_RS11935
uniprot id: A0A7T1T5X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

2710756:G4Z16 RS12135
gene id: 2710756:G4Z16_RS12135
uniprot id: A0A7T1WQK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2710756:G4Z16 RS16065
gene id: 2710756:G4Z16_RS16065
uniprot id: A0A7T1T761
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

2710756:G4Z16 RS08075
gene id: 2710756:G4Z16_RS08075
uniprot id: A0A7T1T4V3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2710756:G4Z16 RS06835
gene id: 2710756:G4Z16_RS06835
uniprot id: A0A7T1WR63
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2710756:G4Z16 RS12115
gene id: 2710756:G4Z16_RS12115
uniprot id: A0A7T1T5X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2710756:G4Z16 RS16225
gene id: 2710756:G4Z16_RS16225
uniprot id: A0A7T1T793
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

2710756:G4Z16 RS12170
gene id: 2710756:G4Z16_RS12170
uniprot id: A0A7T1T600
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.