266940:KRAD RS17265
gene id: 266940:KRAD_RS17265
uniprot id: A6WDB9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

266940:KRAD RS04105
gene id: 266940:KRAD_RS04105
uniprot id: A6W7T9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

266940:KRAD RS03980
gene id: 266940:KRAD_RS03980
uniprot id: A6W7W4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

266940:KRAD RS08845
gene id: 266940:KRAD_RS08845
uniprot id: A6W562
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

266940:KRAD RS07495
gene id: 266940:KRAD_RS07495
uniprot id: A6W5X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

266940:KRAD RS24175
gene id: 266940:KRAD_RS24175
uniprot id: A6W4W0
names: Similarity
messages: Belongs to the peptidase S8 family.

266940:KRAD RS03910
gene id: 266940:KRAD_RS03910
uniprot id: A6W7X8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

266940:KRAD RS13390
gene id: 266940:KRAD_RS13390
uniprot id: A6WFG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS08535
gene id: 266940:KRAD_RS08535
uniprot id: A6W5B7
names: Subcellular Location Annotation
messages: Cytoplasm

266940:KRAD RS04605
gene id: 266940:KRAD_RS04605
uniprot id: A6W7J4
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

266940:KRAD RS04740
gene id: 266940:KRAD_RS04740
uniprot id: A6W7G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

266940:KRAD RS07595
gene id: 266940:KRAD_RS07595
uniprot id: A6W5V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

266940:KRAD RS10520
gene id: 266940:KRAD_RS10520
uniprot id: A6W485
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS05470
gene id: 266940:KRAD_RS05470
uniprot id: A6W725
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

266940:KRAD RS18155
gene id: 266940:KRAD_RS18155
uniprot id: A6WCU2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

266940:KRAD RS12505
gene id: 266940:KRAD_RS12505
uniprot id: A6WFY8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

266940:KRAD RS16335
gene id: 266940:KRAD_RS16335
uniprot id: A6WDU6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

266940:KRAD RS16790
gene id: 266940:KRAD_RS16790
uniprot id: A6WDL0
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

266940:KRAD RS04165
gene id: 266940:KRAD_RS04165
uniprot id: A6W7S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS07895
gene id: 266940:KRAD_RS07895
uniprot id: A6W5P6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

266940:KRAD RS05840
gene id: 266940:KRAD_RS05840
uniprot id: A6W6V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

266940:KRAD RS19120
gene id: 266940:KRAD_RS19120
uniprot id: A6WCA9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

266940:KRAD RS01345
gene id: 266940:KRAD_RS01345
uniprot id: A6W9E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

266940:KRAD RS18215
gene id: 266940:KRAD_RS18215
uniprot id: A6WCT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

266940:KRAD RS05330
gene id: 266940:KRAD_RS05330
uniprot id: A6W754
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

266940:KRAD RS10640
gene id: 266940:KRAD_RS10640
uniprot id: A6W461
names: Similarity
messages: Belongs to the citrate synthase family.

266940:KRAD RS15495
gene id: 266940:KRAD_RS15495
uniprot id: A6WEB3
names: Similarity
messages: Belongs to the UDPGP type 2 family.

266940:KRAD RS23360
gene id: 266940:KRAD_RS23360
uniprot id: A6WH14
names: Similarity
messages: Belongs to the GSP E family.

266940:KRAD RS27520
gene id: 266940:KRAD_RS27520
uniprot id: A6W4J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

266940:KRAD RS11900
gene id: 266940:KRAD_RS11900
uniprot id: A6WGA5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS12025
gene id: 266940:KRAD_RS12025
uniprot id: A6WG83
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

266940:KRAD RS05335
gene id: 266940:KRAD_RS05335
uniprot id: A6W753
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

266940:KRAD RS13350
gene id: 266940:KRAD_RS13350
uniprot id: A6WFH3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

266940:KRAD RS20440
gene id: 266940:KRAD_RS20440
uniprot id: A6WBK5
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS14695
gene id: 266940:KRAD_RS14695
uniprot id: A6WER3
names: Similarity
messages: Belongs to the PGI/PMI family.

266940:KRAD RS12210
gene id: 266940:KRAD_RS12210
uniprot id: A6WG46
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

266940:KRAD RS18880
gene id: 266940:KRAD_RS18880
uniprot id: A6WCF7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

266940:KRAD RS03810
gene id: 266940:KRAD_RS03810
uniprot id: A6W7Z8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

266940:KRAD RS08110
gene id: 266940:KRAD_RS08110
uniprot id: A6W5K3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

266940:KRAD RS04420
gene id: 266940:KRAD_RS04420
uniprot id: A6W7N0
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

266940:KRAD RS04140
gene id: 266940:KRAD_RS04140
uniprot id: A6W7T3
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

266940:KRAD RS02815
gene id: 266940:KRAD_RS02815
uniprot id: A6W8J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

266940:KRAD RS15110
gene id: 266940:KRAD_RS15110
uniprot id: A6WEI6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

266940:KRAD RS20110
gene id: 266940:KRAD_RS20110
uniprot id: A6WBS0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

266940:KRAD RS14050
gene id: 266940:KRAD_RS14050
uniprot id: A6WF41
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS22950
gene id: 266940:KRAD_RS22950
uniprot id: A6WGS5
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS12470
gene id: 266940:KRAD_RS12470
uniprot id: A6WFZ5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

266940:KRAD RS04400
gene id: 266940:KRAD_RS04400
uniprot id: A6W7N4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

266940:KRAD RS15290
gene id: 266940:KRAD_RS15290
uniprot id: A6WEF1
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS03570
gene id: 266940:KRAD_RS03570
uniprot id: A6W846
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

266940:KRAD RS07030
gene id: 266940:KRAD_RS07030
uniprot id: A6W664
names: Similarity
messages: Belongs to the manganese catalase family.

266940:KRAD RS18910
gene id: 266940:KRAD_RS18910
uniprot id: A6WCF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

266940:KRAD RS13835
gene id: 266940:KRAD_RS13835
uniprot id: A6WF83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

266940:KRAD RS00770
gene id: 266940:KRAD_RS00770
uniprot id: A6W9Q9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

266940:KRAD RS18205
gene id: 266940:KRAD_RS18205
uniprot id: A6WCT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

266940:KRAD RS02125
gene id: 266940:KRAD_RS02125
uniprot id: A6W8Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

266940:KRAD RS19100
gene id: 266940:KRAD_RS19100
uniprot id: A6WCB3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS17595
gene id: 266940:KRAD_RS17595
uniprot id: A6WD55
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

266940:KRAD RS03030
gene id: 266940:KRAD_RS03030
uniprot id: A6W8F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

266940:KRAD RS04245
gene id: 266940:KRAD_RS04245
uniprot id: A6W7R2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

266940:KRAD RS03665
gene id: 266940:KRAD_RS03665
uniprot id: A6W828
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

266940:KRAD RS04170
gene id: 266940:KRAD_RS04170
uniprot id: A6W7S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS26100
gene id: 266940:KRAD_RS26100
uniprot id: A6WE69
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

266940:KRAD RS00880
gene id: 266940:KRAD_RS00880
uniprot id: A6W9N5
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS10150
gene id: 266940:KRAD_RS10150
uniprot id: A6W4F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

266940:KRAD RS07435
gene id: 266940:KRAD_RS07435
uniprot id: A6W5Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

266940:KRAD RS15910
gene id: 266940:KRAD_RS15910
uniprot id: A6WE29
names: Subcellular Location Annotation
messages: Cytoplasm

266940:KRAD RS01050
gene id: 266940:KRAD_RS01050
uniprot id: A6W9K1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

266940:KRAD RS15680
gene id: 266940:KRAD_RS15680
uniprot id: A6WE75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

266940:KRAD RS04755
gene id: 266940:KRAD_RS04755
uniprot id: A6W7G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

266940:KRAD RS04095
gene id: 266940:KRAD_RS04095
uniprot id: A6W7U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

266940:KRAD RS19615
gene id: 266940:KRAD_RS19615
uniprot id: A6WC13
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS23125
gene id: 266940:KRAD_RS23125
uniprot id: A6WGW8
names: Subcellular Location Annotation
messages: Cytoplasm

266940:KRAD RS17980
gene id: 266940:KRAD_RS17980
uniprot id: A6WCX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

266940:KRAD RS17740
gene id: 266940:KRAD_RS17740
uniprot id: A6WD26
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

266940:KRAD RS12310
gene id: 266940:KRAD_RS12310
uniprot id: A6WG26
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS12735
gene id: 266940:KRAD_RS12735
uniprot id: A6WFU4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

266940:KRAD RS08540
gene id: 266940:KRAD_RS08540
uniprot id: A6W5B6
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS10240
gene id: 266940:KRAD_RS10240
uniprot id: A6W4E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

266940:KRAD RS05325
gene id: 266940:KRAD_RS05325
uniprot id: A6W755
names: Similarity
messages: Belongs to the GSP E family.

266940:KRAD RS13375
gene id: 266940:KRAD_RS13375
uniprot id: A6WFG8
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS13580
gene id: 266940:KRAD_RS13580
uniprot id: A6WFC7
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS13480
gene id: 266940:KRAD_RS13480
uniprot id: A6WFE7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

266940:KRAD RS05390
gene id: 266940:KRAD_RS05390
uniprot id: A6W741
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS02915
gene id: 266940:KRAD_RS02915
uniprot id: A6W8H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

266940:KRAD RS02080
gene id: 266940:KRAD_RS02080
uniprot id: A6W8Z5
names: Cofactor
messages: Binds 1 FMN per subunit.

266940:KRAD RS07715
gene id: 266940:KRAD_RS07715
uniprot id: A6W5S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

266940:KRAD RS21405
gene id: 266940:KRAD_RS21405
uniprot id: A6WB11
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

266940:KRAD RS27470
gene id: 266940:KRAD_RS27470
uniprot id: A6W6L1
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

266940:KRAD RS10165
gene id: 266940:KRAD_RS10165
uniprot id: A6W4F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

266940:KRAD RS15415
gene id: 266940:KRAD_RS15415
uniprot id: A6WEC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

266940:KRAD RS03765
gene id: 266940:KRAD_RS03765
uniprot id: A6W807
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS05690
gene id: 266940:KRAD_RS05690
uniprot id: A6W6Y2
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS20175
gene id: 266940:KRAD_RS20175
uniprot id: A6WBQ7
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

266940:KRAD RS12045
gene id: 266940:KRAD_RS12045
uniprot id: A6WG79
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

266940:KRAD RS15940
gene id: 266940:KRAD_RS15940
uniprot id: A6WE23
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

266940:KRAD RS15010
gene id: 266940:KRAD_RS15010
uniprot id: A6WEK6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

266940:KRAD RS22375
gene id: 266940:KRAD_RS22375
uniprot id: A6WAE7
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS19020
gene id: 266940:KRAD_RS19020
uniprot id: A6WCC9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS02215
gene id: 266940:KRAD_RS02215
uniprot id: A6W8W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

266940:KRAD RS23075
gene id: 266940:KRAD_RS23075
uniprot id: A6WGV7
names: Similarity
messages: Belongs to the CsoR family.

266940:KRAD RS07730
gene id: 266940:KRAD_RS07730
uniprot id: A6W5S5
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

266940:KRAD RS04770
gene id: 266940:KRAD_RS04770
uniprot id: A6W7G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

266940:KRAD RS08750
gene id: 266940:KRAD_RS08750
uniprot id: A6W578
names: Similarity
messages: Belongs to the GSP E family.

266940:KRAD RS03220
gene id: 266940:KRAD_RS03220
uniprot id: A6W8B3
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

266940:KRAD RS12395
gene id: 266940:KRAD_RS12395
uniprot id: A6WG10
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

266940:KRAD RS08480
gene id: 266940:KRAD_RS08480
uniprot id: A6W5C7
names: Similarity
messages: Belongs to the peptidase S13 family.

266940:KRAD RS07490
gene id: 266940:KRAD_RS07490
uniprot id: A6W5X4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

266940:KRAD RS12265
gene id: 266940:KRAD_RS12265
uniprot id: A6WG35
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS04060
gene id: 266940:KRAD_RS04060
uniprot id: A6W7U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

266940:KRAD RS14375
gene id: 266940:KRAD_RS14375
uniprot id: A6WEX7
names: Similarity
messages: Belongs to the peptidase S33 family.

266940:KRAD RS11240
gene id: 266940:KRAD_RS11240
uniprot id: A6WGM4
names: Similarity
messages: Belongs to the thioredoxin family.

266940:KRAD RS16380
gene id: 266940:KRAD_RS16380
uniprot id: A6WDT9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

266940:KRAD RS11895
gene id: 266940:KRAD_RS11895
uniprot id: A6WGA6
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

266940:KRAD RS13240
gene id: 266940:KRAD_RS13240
uniprot id: A6WFJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

266940:KRAD RS17955
gene id: 266940:KRAD_RS17955
uniprot id: A6WCY3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

266940:KRAD RS06110
gene id: 266940:KRAD_RS06110
uniprot id: A6W6P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

266940:KRAD RS22645
gene id: 266940:KRAD_RS22645
uniprot id: A6WA87
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

266940:KRAD RS05890
gene id: 266940:KRAD_RS05890
uniprot id: A6W6U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

266940:KRAD RS05685
gene id: 266940:KRAD_RS05685
uniprot id: A6W6Y3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

266940:KRAD RS06185
gene id: 266940:KRAD_RS06185
uniprot id: A6W6N4
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

266940:KRAD RS12300
gene id: 266940:KRAD_RS12300
uniprot id: A6WG28
names: Similarity
messages: Belongs to the ketopantoate reductase family.

266940:KRAD RS09950
gene id: 266940:KRAD_RS09950
uniprot id: A6W4J5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

266940:KRAD RS10475
gene id: 266940:KRAD_RS10475
uniprot id: A6W494
names: Similarity
messages: Belongs to the HSP15 family.

266940:KRAD RS15490
gene id: 266940:KRAD_RS15490
uniprot id: A6WEB4
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

266940:KRAD RS13945
gene id: 266940:KRAD_RS13945
uniprot id: A6WF61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

266940:KRAD RS14265
gene id: 266940:KRAD_RS14265
uniprot id: A6WEZ9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

266940:KRAD RS13940
gene id: 266940:KRAD_RS13940
uniprot id: A6WF62
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

266940:KRAD RS02835
gene id: 266940:KRAD_RS02835
uniprot id: A6W8I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

266940:KRAD RS04185
gene id: 266940:KRAD_RS04185
uniprot id: A6W7S4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

266940:KRAD RS13950
gene id: 266940:KRAD_RS13950
uniprot id: A6WF60
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

266940:KRAD RS18575
gene id: 266940:KRAD_RS18575
uniprot id: A6WCL3
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS19780
gene id: 266940:KRAD_RS19780
uniprot id: A6WBY2
names: Similarity
messages: Belongs to the peptidase S33 family.

266940:KRAD RS01480
gene id: 266940:KRAD_RS01480
uniprot id: A6W9B4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.

266940:KRAD RS25690
gene id: 266940:KRAD_RS25690
uniprot id: A6WF43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS16685
gene id: 266940:KRAD_RS16685
uniprot id: A6WDN0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

266940:KRAD RS05170
gene id: 266940:KRAD_RS05170
uniprot id: A6W787
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS07615
gene id: 266940:KRAD_RS07615
uniprot id: A6W5U9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

266940:KRAD RS17555
gene id: 266940:KRAD_RS17555
uniprot id: A6WD63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

266940:KRAD RS00690
gene id: 266940:KRAD_RS00690
uniprot id: A6W9S5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

266940:KRAD RS11680
gene id: 266940:KRAD_RS11680
uniprot id: A6WGE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS07465
gene id: 266940:KRAD_RS07465
uniprot id: A6W5X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

266940:KRAD RS05445
gene id: 266940:KRAD_RS05445
uniprot id: A6W730
names: Similarity
messages: Belongs to the Nudix hydrolase family.

266940:KRAD RS06840
gene id: 266940:KRAD_RS06840
uniprot id: A6W6A5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

266940:KRAD RS18775
gene id: 266940:KRAD_RS18775
uniprot id: A6WCH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

266940:KRAD RS17860
gene id: 266940:KRAD_RS17860
uniprot id: A6WD02
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

266940:KRAD RS02980
gene id: 266940:KRAD_RS02980
uniprot id: A6W8G0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

266940:KRAD RS20280
gene id: 266940:KRAD_RS20280
uniprot id: A6WBN8
names: Similarity
messages: Belongs to the YciI family.

266940:KRAD RS05070
gene id: 266940:KRAD_RS05070
uniprot id: A6W7A5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

266940:KRAD RS07695
gene id: 266940:KRAD_RS07695
uniprot id: A6W5T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

266940:KRAD RS16190
gene id: 266940:KRAD_RS16190
uniprot id: A6WDX4
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS00575
gene id: 266940:KRAD_RS00575
uniprot id: A6W9U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

266940:KRAD RS04750
gene id: 266940:KRAD_RS04750
uniprot id: A6W7G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

266940:KRAD RS14185
gene id: 266940:KRAD_RS14185
uniprot id: A6WF15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

266940:KRAD RS12615
gene id: 266940:KRAD_RS12615
uniprot id: A6WFW7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS15725
gene id: 266940:KRAD_RS15725
uniprot id: A6WE66
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS04490
gene id: 266940:KRAD_RS04490
uniprot id: A6W7L7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

266940:KRAD RS12125
gene id: 266940:KRAD_RS12125
uniprot id: A6WG63
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

266940:KRAD RS10085
gene id: 266940:KRAD_RS10085
uniprot id: A6W4G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

266940:KRAD RS10185
gene id: 266940:KRAD_RS10185
uniprot id: A6W4F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

266940:KRAD RS12435
gene id: 266940:KRAD_RS12435
uniprot id: A6WG02
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS04905
gene id: 266940:KRAD_RS04905
uniprot id: A6W7D7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS13210
gene id: 266940:KRAD_RS13210
uniprot id: A6WFJ9
names: Similarity
messages: Belongs to the peptidase C56 family.

266940:KRAD RS18875
gene id: 266940:KRAD_RS18875
uniprot id: A6WCF8
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

266940:KRAD RS03640
gene id: 266940:KRAD_RS03640
uniprot id: A6W833
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

266940:KRAD RS21580
gene id: 266940:KRAD_RS21580
uniprot id: A6WAX0
names: Similarity
messages: Belongs to the FBPase class 2 family.

266940:KRAD RS18315
gene id: 266940:KRAD_RS18315
uniprot id: A6WCR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

266940:KRAD RS02855
gene id: 266940:KRAD_RS02855
uniprot id: A6W8I5
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS13215
gene id: 266940:KRAD_RS13215
uniprot id: A6WFJ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

266940:KRAD RS05010
gene id: 266940:KRAD_RS05010
uniprot id: A6W7B6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

266940:KRAD RS04555
gene id: 266940:KRAD_RS04555
uniprot id: A6W7K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS05570
gene id: 266940:KRAD_RS05570
uniprot id: A6W705
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS04055
gene id: 266940:KRAD_RS04055
uniprot id: A6W7U9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

266940:KRAD RS16290
gene id: 266940:KRAD_RS16290
uniprot id: A6WDV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

266940:KRAD RS11205
gene id: 266940:KRAD_RS11205
uniprot id: A6WGN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

266940:KRAD RS10860
gene id: 266940:KRAD_RS10860
uniprot id: A6W418
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

266940:KRAD RS13645
gene id: 266940:KRAD_RS13645
uniprot id: A6WFB5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

266940:KRAD RS12015
gene id: 266940:KRAD_RS12015
uniprot id: A6WG85
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS14980
gene id: 266940:KRAD_RS14980
uniprot id: A6WEL1
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS01885
gene id: 266940:KRAD_RS01885
uniprot id: A6W933
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

266940:KRAD RS16455
gene id: 266940:KRAD_RS16455
uniprot id: A6WDS4
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS16800
gene id: 266940:KRAD_RS16800
uniprot id: A6WDK8
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS06100
gene id: 266940:KRAD_RS06100
uniprot id: A6W6Q1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

266940:KRAD RS11410
gene id: 266940:KRAD_RS11410
uniprot id: A6WGJ0
names: Similarity
messages: Belongs to the asp23 family.

266940:KRAD RS07175
gene id: 266940:KRAD_RS07175
uniprot id: A6W635
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

266940:KRAD RS01255
gene id: 266940:KRAD_RS01255
uniprot id: A6W9G0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

266940:KRAD RS13890
gene id: 266940:KRAD_RS13890
uniprot id: A6WF72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

266940:KRAD RS02800
gene id: 266940:KRAD_RS02800
uniprot id: A6W8J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

266940:KRAD RS10975
gene id: 266940:KRAD_RS10975
uniprot id: A6W3Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

266940:KRAD RS06395
gene id: 266940:KRAD_RS06395
uniprot id: A6W6J4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

266940:KRAD RS11210
gene id: 266940:KRAD_RS11210
uniprot id: A6WGN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

266940:KRAD RS14200
gene id: 266940:KRAD_RS14200
uniprot id: A6WF12
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

266940:KRAD RS07795
gene id: 266940:KRAD_RS07795
uniprot id: A6W5R3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

266940:KRAD RS04485
gene id: 266940:KRAD_RS04485
uniprot id: A6W7L8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

266940:KRAD RS11285
gene id: 266940:KRAD_RS11285
uniprot id: A6WGL5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

266940:KRAD RS16170
gene id: 266940:KRAD_RS16170
uniprot id: A6WDX8
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

266940:KRAD RS01705
gene id: 266940:KRAD_RS01705
uniprot id: A6W969
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

266940:KRAD RS19405
gene id: 266940:KRAD_RS19405
uniprot id: A6WC54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

266940:KRAD RS07980
gene id: 266940:KRAD_RS07980
uniprot id: A6W5N0
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS18585
gene id: 266940:KRAD_RS18585
uniprot id: A6WCL1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

266940:KRAD RS04495
gene id: 266940:KRAD_RS04495
uniprot id: A6W7L6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

266940:KRAD RS02070
gene id: 266940:KRAD_RS02070
uniprot id: A6W8Z7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

266940:KRAD RS14025
gene id: 266940:KRAD_RS14025
uniprot id: A6WF46
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

266940:KRAD RS10650
gene id: 266940:KRAD_RS10650
uniprot id: A6W459
names: Similarity
messages: Belongs to the PrpD family.

266940:KRAD RS22965
gene id: 266940:KRAD_RS22965
uniprot id: A6WGT0
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS17235
gene id: 266940:KRAD_RS17235
uniprot id: A6WDC5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

266940:KRAD RS14230
gene id: 266940:KRAD_RS14230
uniprot id: A6WF06
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

266940:KRAD RS04940
gene id: 266940:KRAD_RS04940
uniprot id: A6W7D0
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaB1 subfamily.
messages: Involved in the purine-salvage pathway. Catalyzes the NADPH-dependent conversion of GMP to IMP.

266940:KRAD RS10965
gene id: 266940:KRAD_RS10965
uniprot id: A6W3Z7
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS06470
gene id: 266940:KRAD_RS06470
uniprot id: A6W6I0
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

266940:KRAD RS23820
gene id: 266940:KRAD_RS23820
uniprot id: A6W9H2
names: Similarity
messages: Belongs to the AHA1 family.

266940:KRAD RS07665
gene id: 266940:KRAD_RS07665
uniprot id: A6W5T9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

266940:KRAD RS07650
gene id: 266940:KRAD_RS07650
uniprot id: A6W5U2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

266940:KRAD RS00435
gene id: 266940:KRAD_RS00435
uniprot id: A6W9X6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

266940:KRAD RS21470
gene id: 266940:KRAD_RS21470
uniprot id: A6WAZ2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

266940:KRAD RS12955
gene id: 266940:KRAD_RS12955
uniprot id: A6WFQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

266940:KRAD RS15335
gene id: 266940:KRAD_RS15335
uniprot id: A6WEE3
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS13450
gene id: 266940:KRAD_RS13450
uniprot id: A6WFF3
names: Similarity
messages: Belongs to the CdaR family.

266940:KRAD RS13590
gene id: 266940:KRAD_RS13590
uniprot id: A6WFC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

266940:KRAD RS16445
gene id: 266940:KRAD_RS16445
uniprot id: A6WDS6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

266940:KRAD RS12675
gene id: 266940:KRAD_RS12675
uniprot id: A6WFV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

266940:KRAD RS13795
gene id: 266940:KRAD_RS13795
uniprot id: A6WF90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS14505
gene id: 266940:KRAD_RS14505
uniprot id: A6WEV1
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

266940:KRAD RS08445
gene id: 266940:KRAD_RS08445
uniprot id: A6W5D4
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

266940:KRAD RS04015
gene id: 266940:KRAD_RS04015
uniprot id: A6W7V7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

266940:KRAD RS16365
gene id: 266940:KRAD_RS16365
uniprot id: A6WDU2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

266940:KRAD RS03800
gene id: 266940:KRAD_RS03800
uniprot id: A6W800
names: Similarity
messages: Belongs to the PspA/IM30 family.

266940:KRAD RS10450
gene id: 266940:KRAD_RS10450
uniprot id: A6W499
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

266940:KRAD RS08365
gene id: 266940:KRAD_RS08365
uniprot id: A6W5F0
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

266940:KRAD RS16990
gene id: 266940:KRAD_RS16990
uniprot id: A6WDH1
names: Similarity
messages: Belongs to the FPG family.

266940:KRAD RS13200
gene id: 266940:KRAD_RS13200
uniprot id: A6WFK1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

266940:KRAD RS03340
gene id: 266940:KRAD_RS03340
uniprot id: A6W890
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

266940:KRAD RS18030
gene id: 266940:KRAD_RS18030
uniprot id: A6WCW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

266940:KRAD RS13565
gene id: 266940:KRAD_RS13565
uniprot id: A6WFD0
names: Similarity
messages: Belongs to the TPP enzyme family.

266940:KRAD RS01745
gene id: 266940:KRAD_RS01745
uniprot id: A6W961
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

266940:KRAD RS07620
gene id: 266940:KRAD_RS07620
uniprot id: A6W5U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

266940:KRAD RS07925
gene id: 266940:KRAD_RS07925
uniprot id: A6W5P1
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS17735
gene id: 266940:KRAD_RS17735
uniprot id: A6WD27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

266940:KRAD RS16665
gene id: 266940:KRAD_RS16665
uniprot id: A6WDN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS03060
gene id: 266940:KRAD_RS03060
uniprot id: A6W8E5
names: Similarity
messages: Belongs to the asp23 family.

266940:KRAD RS09090
gene id: 266940:KRAD_RS09090
uniprot id: A6W512
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS00205
gene id: 266940:KRAD_RS00205
uniprot id: A6WA25
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

266940:KRAD RS10220
gene id: 266940:KRAD_RS10220
uniprot id: A6W4E4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

266940:KRAD RS06790
gene id: 266940:KRAD_RS06790
uniprot id: A6W6B5
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

266940:KRAD RS10765
gene id: 266940:KRAD_RS10765
uniprot id: A6W436
names: Similarity
messages: Belongs to the RutC family.

266940:KRAD RS07395
gene id: 266940:KRAD_RS07395
uniprot id: A6W5Z3
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

266940:KRAD RS27590
gene id: 266940:KRAD_RS27590
uniprot id: A6WEP9
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS04030
gene id: 266940:KRAD_RS04030
uniprot id: A6W7V4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

266940:KRAD RS11315
gene id: 266940:KRAD_RS11315
uniprot id: A6WGK9
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS24290
gene id: 266940:KRAD_RS24290
uniprot id: A6W3X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

266940:KRAD RS04785
gene id: 266940:KRAD_RS04785
uniprot id: A6W7G0
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS10645
gene id: 266940:KRAD_RS10645
uniprot id: A6W460
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

266940:KRAD RS14385
gene id: 266940:KRAD_RS14385
uniprot id: A6WEX5
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

266940:KRAD RS16775
gene id: 266940:KRAD_RS16775
uniprot id: A6WDL3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

266940:KRAD RS07015
gene id: 266940:KRAD_RS07015
uniprot id: A6W667
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

266940:KRAD RS23450
gene id: 266940:KRAD_RS23450
uniprot id: A6WH32
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

266940:KRAD RS18175
gene id: 266940:KRAD_RS18175
uniprot id: A6WCT8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Tetramer of two alpha and two beta subunits.

266940:KRAD RS17040
gene id: 266940:KRAD_RS17040
uniprot id: A6WDG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

266940:KRAD RS21310
gene id: 266940:KRAD_RS21310
uniprot id: A6WB30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS13395
gene id: 266940:KRAD_RS13395
uniprot id: A6WFG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS18445
gene id: 266940:KRAD_RS18445
uniprot id: A6WCN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

266940:KRAD RS17800
gene id: 266940:KRAD_RS17800
uniprot id: A6WD14
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

266940:KRAD RS22750
gene id: 266940:KRAD_RS22750
uniprot id: A6WA66
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

266940:KRAD RS12140
gene id: 266940:KRAD_RS12140
uniprot id: A6WG60
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

266940:KRAD RS09710
gene id: 266940:KRAD_RS09710
uniprot id: A6W4P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

266940:KRAD RS14415
gene id: 266940:KRAD_RS14415
uniprot id: A6WEW9
names: Similarity
messages: Belongs to the FGGY kinase family.

266940:KRAD RS19395
gene id: 266940:KRAD_RS19395
uniprot id: A6WC56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

266940:KRAD RS05165
gene id: 266940:KRAD_RS05165
uniprot id: A6W788
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

266940:KRAD RS18115
gene id: 266940:KRAD_RS18115
uniprot id: A6WCV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

266940:KRAD RS12170
gene id: 266940:KRAD_RS12170
uniprot id: A6WG54
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

266940:KRAD RS08840
gene id: 266940:KRAD_RS08840
uniprot id: A6W563
names: Subunit
messages: Homodimer.

266940:KRAD RS17120
gene id: 266940:KRAD_RS17120
uniprot id: A6WDE5
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

266940:KRAD RS18265
gene id: 266940:KRAD_RS18265
uniprot id: A6WCS4
names: Similarity
messages: Belongs to the TlyA family.

266940:KRAD RS17985
gene id: 266940:KRAD_RS17985
uniprot id: A6WCX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane

266940:KRAD RS04735
gene id: 266940:KRAD_RS04735
uniprot id: A6W7H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

266940:KRAD RS03410
gene id: 266940:KRAD_RS03410
uniprot id: A6W878
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS09795
gene id: 266940:KRAD_RS09795
uniprot id: A6W4M6
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS07560
gene id: 266940:KRAD_RS07560
uniprot id: A6W5W0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

266940:KRAD RS08265
gene id: 266940:KRAD_RS08265
uniprot id: A6W5H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

266940:KRAD RS12815
gene id: 266940:KRAD_RS12815
uniprot id: A6WFS8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

266940:KRAD RS21380
gene id: 266940:KRAD_RS21380
uniprot id: A6WB16
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

266940:KRAD RS06160
gene id: 266940:KRAD_RS06160
uniprot id: A6W6N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

266940:KRAD RS14720
gene id: 266940:KRAD_RS14720
uniprot id: A6WEQ8
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS01515
gene id: 266940:KRAD_RS01515
uniprot id: A6W9A7
names: Function
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

266940:KRAD RS08000
gene id: 266940:KRAD_RS08000
uniprot id: A6W5M6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

266940:KRAD RS12660
gene id: 266940:KRAD_RS12660
uniprot id: A6WFV9
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS15015
gene id: 266940:KRAD_RS15015
uniprot id: A6WEK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

266940:KRAD RS07825
gene id: 266940:KRAD_RS07825
uniprot id: A6W5R0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane

266940:KRAD RS07870
gene id: 266940:KRAD_RS07870
uniprot id: A6W5Q1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

266940:KRAD RS21315
gene id: 266940:KRAD_RS21315
uniprot id: A6WB29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS18210
gene id: 266940:KRAD_RS18210
uniprot id: A6WCT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

266940:KRAD RS17580
gene id: 266940:KRAD_RS17580
uniprot id: A6WD58
names: Similarity
messages: Belongs to the peptidase S51 family.

266940:KRAD RS20485
gene id: 266940:KRAD_RS20485
uniprot id: A6WBJ6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

266940:KRAD RS01740
gene id: 266940:KRAD_RS01740
uniprot id: A6W962
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

266940:KRAD RS13080
gene id: 266940:KRAD_RS13080
uniprot id: A6WFM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

266940:KRAD RS17930
gene id: 266940:KRAD_RS17930
uniprot id: A6WCY8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

266940:KRAD RS15670
gene id: 266940:KRAD_RS15670
uniprot id: A6WE77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS02715
gene id: 266940:KRAD_RS02715
uniprot id: A6W8L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

266940:KRAD RS01715
gene id: 266940:KRAD_RS01715
uniprot id: A6W967
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS19330
gene id: 266940:KRAD_RS19330
uniprot id: A6WC69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

266940:KRAD RS03735
gene id: 266940:KRAD_RS03735
uniprot id: A6W814
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

266940:KRAD RS10195
gene id: 266940:KRAD_RS10195
uniprot id: A6W4E9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

266940:KRAD RS18195
gene id: 266940:KRAD_RS18195
uniprot id: A6WCT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

266940:KRAD RS04260
gene id: 266940:KRAD_RS04260
uniprot id: A6W7Q9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

266940:KRAD RS10820
gene id: 266940:KRAD_RS10820
uniprot id: A6W426
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS10470
gene id: 266940:KRAD_RS10470
uniprot id: A6W495
names: Similarity
messages: Belongs to the phosphohexose mutase family.

266940:KRAD RS18055
gene id: 266940:KRAD_RS18055
uniprot id: A6WCW3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

266940:KRAD RS03780
gene id: 266940:KRAD_RS03780
uniprot id: A6W804
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

266940:KRAD RS18110
gene id: 266940:KRAD_RS18110
uniprot id: A6WCV1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

266940:KRAD RS04795
gene id: 266940:KRAD_RS04795
uniprot id: A6W7F8
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

266940:KRAD RS04075
gene id: 266940:KRAD_RS04075
uniprot id: A6W7U5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

266940:KRAD RS07975
gene id: 266940:KRAD_RS07975
uniprot id: A6W5N1
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS20075
gene id: 266940:KRAD_RS20075
uniprot id: A6WBS7
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS14195
gene id: 266940:KRAD_RS14195
uniprot id: A6WF13
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS09745
gene id: 266940:KRAD_RS09745
uniprot id: A6W4N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

266940:KRAD RS02095
gene id: 266940:KRAD_RS02095
uniprot id: A6W8Z2
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

266940:KRAD RS14450
gene id: 266940:KRAD_RS14450
uniprot id: A6WEW2
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

266940:KRAD RS05610
gene id: 266940:KRAD_RS05610
uniprot id: A6W6Z8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

266940:KRAD RS17045
gene id: 266940:KRAD_RS17045
uniprot id: A6WDG0
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS04925
gene id: 266940:KRAD_RS04925
uniprot id: A6W7D3
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS19105
gene id: 266940:KRAD_RS19105
uniprot id: A6WCB2
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

266940:KRAD RS04550
gene id: 266940:KRAD_RS04550
uniprot id: A6W7K5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

266940:KRAD RS14035
gene id: 266940:KRAD_RS14035
uniprot id: A6WF44
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

266940:KRAD RS16120
gene id: 266940:KRAD_RS16120
uniprot id: A6WDY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS07840
gene id: 266940:KRAD_RS07840
uniprot id: A6W5Q7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

266940:KRAD RS24365
gene id: 266940:KRAD_RS24365
uniprot id: A6WG69
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS13925
gene id: 266940:KRAD_RS13925
uniprot id: A6WF65
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

266940:KRAD RS19060
gene id: 266940:KRAD_RS19060
uniprot id: A6WCC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

266940:KRAD RS02825
gene id: 266940:KRAD_RS02825
uniprot id: A6W8J1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

266940:KRAD RS09375
gene id: 266940:KRAD_RS09375
uniprot id: A6W4V6
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

266940:KRAD RS18015
gene id: 266940:KRAD_RS18015
uniprot id: A6WCX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

266940:KRAD RS09170
gene id: 266940:KRAD_RS09170
uniprot id: A6W4Z6
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS01005
gene id: 266940:KRAD_RS01005
uniprot id: A6W9L0
names: Similarity
messages: Belongs to the DapA family.

266940:KRAD RS02740
gene id: 266940:KRAD_RS02740
uniprot id: A6W8K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

266940:KRAD RS19000
gene id: 266940:KRAD_RS19000
uniprot id: A6WCD3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

266940:KRAD RS12970
gene id: 266940:KRAD_RS12970
uniprot id: A6WFP7
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS03550
gene id: 266940:KRAD_RS03550
uniprot id: A6W849
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

266940:KRAD RS16705
gene id: 266940:KRAD_RS16705
uniprot id: A6WDM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

266940:KRAD RS08485
gene id: 266940:KRAD_RS08485
uniprot id: A6W5C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

266940:KRAD RS08890
gene id: 266940:KRAD_RS08890
uniprot id: A6W552
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS04045
gene id: 266940:KRAD_RS04045
uniprot id: A6W7V1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

266940:KRAD RS10795
gene id: 266940:KRAD_RS10795
uniprot id: A6W430
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

266940:KRAD RS16865
gene id: 266940:KRAD_RS16865
uniprot id: A6WDJ6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

266940:KRAD RS15020
gene id: 266940:KRAD_RS15020
uniprot id: A6WEK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

266940:KRAD RS08050
gene id: 266940:KRAD_RS08050
uniprot id: A6W5L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

266940:KRAD RS09000
gene id: 266940:KRAD_RS09000
uniprot id: A6W531
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS03480
gene id: 266940:KRAD_RS03480
uniprot id: A6W863
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

266940:KRAD RS16530
gene id: 266940:KRAD_RS16530
uniprot id: A6WDR1
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

266940:KRAD RS04920
gene id: 266940:KRAD_RS04920
uniprot id: A6W7D4
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS14665
gene id: 266940:KRAD_RS14665
uniprot id: A6WER9
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

266940:KRAD RS18275
gene id: 266940:KRAD_RS18275
uniprot id: A6WCS2
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

266940:KRAD RS07110
gene id: 266940:KRAD_RS07110
uniprot id: A6W648
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS11100
gene id: 266940:KRAD_RS11100
uniprot id: A6W3X1
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS24000
gene id: 266940:KRAD_RS24000
uniprot id: A6W6W7
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

266940:KRAD RS04815
gene id: 266940:KRAD_RS04815
uniprot id: A6W7F4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS16145
gene id: 266940:KRAD_RS16145
uniprot id: A6WDY3
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

266940:KRAD RS12545
gene id: 266940:KRAD_RS12545
uniprot id: A6WFY0
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS07735
gene id: 266940:KRAD_RS07735
uniprot id: A6W5S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

266940:KRAD RS11130
gene id: 266940:KRAD_RS11130
uniprot id: A6W3W5
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS17995
gene id: 266940:KRAD_RS17995
uniprot id: A6WCX5
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS08215
gene id: 266940:KRAD_RS08215
uniprot id: A6W5I2
names: Similarity
messages: Belongs to the UxaA family.

266940:KRAD RS15445
gene id: 266940:KRAD_RS15445
uniprot id: A6WEC3
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

266940:KRAD RS14580
gene id: 266940:KRAD_RS14580
uniprot id: A6WET6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

266940:KRAD RS17080
gene id: 266940:KRAD_RS17080
uniprot id: A6WDF3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

266940:KRAD RS04895
gene id: 266940:KRAD_RS04895
uniprot id: A6W7D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

266940:KRAD RS10270
gene id: 266940:KRAD_RS10270
uniprot id: A6W4D4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.
messages: Decarboxylates branched-chain and aromatic alpha-keto acids to aldehydes.

266940:KRAD RS03595
gene id: 266940:KRAD_RS03595
uniprot id: A6W841
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

266940:KRAD RS17615
gene id: 266940:KRAD_RS17615
uniprot id: A6WD51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

266940:KRAD RS03575
gene id: 266940:KRAD_RS03575
uniprot id: A6W845
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

266940:KRAD RS07645
gene id: 266940:KRAD_RS07645
uniprot id: A6W5U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

266940:KRAD RS09285
gene id: 266940:KRAD_RS09285
uniprot id: A6W4X3
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

266940:KRAD RS03125
gene id: 266940:KRAD_RS03125
uniprot id: A6W8D2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS06155
gene id: 266940:KRAD_RS06155
uniprot id: A6W6P0
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

266940:KRAD RS20155
gene id: 266940:KRAD_RS20155
uniprot id: A6WBR1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

266940:KRAD RS03700
gene id: 266940:KRAD_RS03700
uniprot id: A6W821
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

266940:KRAD RS10280
gene id: 266940:KRAD_RS10280
uniprot id: A6W4D2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.
messages: cell wall

266940:KRAD RS27430
gene id: 266940:KRAD_RS27430
uniprot id: A6W887
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

266940:KRAD RS18120
gene id: 266940:KRAD_RS18120
uniprot id: A6WCU9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

266940:KRAD RS04560
gene id: 266940:KRAD_RS04560
uniprot id: A6W7K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS19985
gene id: 266940:KRAD_RS19985
uniprot id: A6WBU5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

266940:KRAD RS06420
gene id: 266940:KRAD_RS06420
uniprot id: A6W6J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS08545
gene id: 266940:KRAD_RS08545
uniprot id: A6W5B5
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS07040
gene id: 266940:KRAD_RS07040
uniprot id: A6W662
names: Similarity
messages: Belongs to the OsmC/Ohr family.

266940:KRAD RS18435
gene id: 266940:KRAD_RS18435
uniprot id: A6WCP0
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

266940:KRAD RS11595
gene id: 266940:KRAD_RS11595
uniprot id: A6WGF3
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS15640
gene id: 266940:KRAD_RS15640
uniprot id: A6WE83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

266940:KRAD RS05550
gene id: 266940:KRAD_RS05550
uniprot id: A6W709
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

266940:KRAD RS07385
gene id: 266940:KRAD_RS07385
uniprot id: A6W5Z5
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS05050
gene id: 266940:KRAD_RS05050
uniprot id: A6W7A9
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS15735
gene id: 266940:KRAD_RS15735
uniprot id: A6WE64
names: Similarity
messages: Belongs to the aldose epimerase family.

266940:KRAD RS05080
gene id: 266940:KRAD_RS05080
uniprot id: A6W7A3
names: Similarity
messages: Belongs to the universal stress protein A family.

266940:KRAD RS03020
gene id: 266940:KRAD_RS03020
uniprot id: A6W8F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

266940:KRAD RS27665
gene id: 266940:KRAD_RS27665
uniprot id: A6WDA8
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS05990
gene id: 266940:KRAD_RS05990
uniprot id: A6W6S4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

266940:KRAD RS09070
gene id: 266940:KRAD_RS09070
uniprot id: A6W516
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS03440
gene id: 266940:KRAD_RS03440
uniprot id: A6W872
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS10380
gene id: 266940:KRAD_RS10380
uniprot id: A6W4B2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

266940:KRAD RS02955
gene id: 266940:KRAD_RS02955
uniprot id: A6W8G5
names: Similarity
messages: Belongs to the UPF0098 family.

266940:KRAD RS13500
gene id: 266940:KRAD_RS13500
uniprot id: A6WFE3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

266940:KRAD RS07635
gene id: 266940:KRAD_RS07635
uniprot id: A6W5U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

266940:KRAD RS11785
gene id: 266940:KRAD_RS11785
uniprot id: A6WGC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS14270
gene id: 266940:KRAD_RS14270
uniprot id: A6WEZ8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

266940:KRAD RS06575
gene id: 266940:KRAD_RS06575
uniprot id: A6W6F9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

266940:KRAD RS01655
gene id: 266940:KRAD_RS01655
uniprot id: A6W979
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

266940:KRAD RS07150
gene id: 266940:KRAD_RS07150
uniprot id: A6W640
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

266940:KRAD RS10200
gene id: 266940:KRAD_RS10200
uniprot id: A6W4E8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

266940:KRAD RS18750
gene id: 266940:KRAD_RS18750
uniprot id: A6WCI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

266940:KRAD RS14290
gene id: 266940:KRAD_RS14290
uniprot id: A6WEZ4
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

266940:KRAD RS07540
gene id: 266940:KRAD_RS07540
uniprot id: A6W5W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

266940:KRAD RS15950
gene id: 266940:KRAD_RS15950
uniprot id: A6WE21
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

266940:KRAD RS08070
gene id: 266940:KRAD_RS08070
uniprot id: A6W5L1
names: Similarity
messages: Belongs to the histone deacetylase family.

266940:KRAD RS08040
gene id: 266940:KRAD_RS08040
uniprot id: A6W5L8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

266940:KRAD RS17085
gene id: 266940:KRAD_RS17085
uniprot id: A6WDF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

266940:KRAD RS06370
gene id: 266940:KRAD_RS06370
uniprot id: A6W6J8
names: Similarity
messages: Belongs to the universal stress protein A family.

266940:KRAD RS19410
gene id: 266940:KRAD_RS19410
uniprot id: A6WC53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

266940:KRAD RS17010
gene id: 266940:KRAD_RS17010
uniprot id: A6WDG7
names: Similarity
messages: Belongs to the peptidase M42 family.

266940:KRAD RS17260
gene id: 266940:KRAD_RS17260
uniprot id: A6WDC0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

266940:KRAD RS18580
gene id: 266940:KRAD_RS18580
uniprot id: A6WCL2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

266940:KRAD RS00915
gene id: 266940:KRAD_RS00915
uniprot id: A6W9M8
names: Similarity
messages: Belongs to the peptidase C56 family.

266940:KRAD RS01650
gene id: 266940:KRAD_RS01650
uniprot id: A6W980
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

266940:KRAD RS04860
gene id: 266940:KRAD_RS04860
uniprot id: A6W7E6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

266940:KRAD RS18530
gene id: 266940:KRAD_RS18530
uniprot id: A6WCM2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

266940:KRAD RS03240
gene id: 266940:KRAD_RS03240
uniprot id: A6W8B0
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS17220
gene id: 266940:KRAD_RS17220
uniprot id: A6WDC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

266940:KRAD RS06755
gene id: 266940:KRAD_RS06755
uniprot id: A6W6C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

266940:KRAD RS16340
gene id: 266940:KRAD_RS16340
uniprot id: A6WDU5
names: Similarity
messages: Belongs to the FPG family.

266940:KRAD RS05695
gene id: 266940:KRAD_RS05695
uniprot id: A6W6Y1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

266940:KRAD RS14970
gene id: 266940:KRAD_RS14970
uniprot id: A6WEL3
names: Similarity
messages: Belongs to the GSP E family.

266940:KRAD RS13790
gene id: 266940:KRAD_RS13790
uniprot id: A6WF91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS18035
gene id: 266940:KRAD_RS18035
uniprot id: A6WCW7
names: Similarity
messages: Belongs to the YggT family.

266940:KRAD RS02810
gene id: 266940:KRAD_RS02810
uniprot id: A6W8J5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

266940:KRAD RS09115
gene id: 266940:KRAD_RS09115
uniprot id: A6W507
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

266940:KRAD RS11905
gene id: 266940:KRAD_RS11905
uniprot id: A6WGA4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

266940:KRAD RS03830
gene id: 266940:KRAD_RS03830
uniprot id: A6W7Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

266940:KRAD RS14160
gene id: 266940:KRAD_RS14160
uniprot id: A6WF19
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

266940:KRAD RS07430
gene id: 266940:KRAD_RS07430
uniprot id: A6W5Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

266940:KRAD RS06585
gene id: 266940:KRAD_RS06585
uniprot id: A6W6F7
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS25975
gene id: 266940:KRAD_RS25975
uniprot id: A6W4D5
names: Similarity
messages: Belongs to the AHA1 family.

266940:KRAD RS19215
gene id: 266940:KRAD_RS19215
uniprot id: A6WC90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

266940:KRAD RS06770
gene id: 266940:KRAD_RS06770
uniprot id: A6W6B9
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

266940:KRAD RS06860
gene id: 266940:KRAD_RS06860
uniprot id: A6W6A1
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

266940:KRAD RS04270
gene id: 266940:KRAD_RS04270
uniprot id: A6W7Q7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

266940:KRAD RS07815
gene id: 266940:KRAD_RS07815
uniprot id: A6W5R2
names: Similarity
messages: Belongs to the UPF0234 family.

266940:KRAD RS03375
gene id: 266940:KRAD_RS03375
uniprot id: A6W885
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

266940:KRAD RS13650
gene id: 266940:KRAD_RS13650
uniprot id: A6WFB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

266940:KRAD RS07685
gene id: 266940:KRAD_RS07685
uniprot id: A6W5T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

266940:KRAD RS15855
gene id: 266940:KRAD_RS15855
uniprot id: A6WE40
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

266940:KRAD RS20140
gene id: 266940:KRAD_RS20140
uniprot id: A6WBR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS05885
gene id: 266940:KRAD_RS05885
uniprot id: A6W6U5
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

266940:KRAD RS06765
gene id: 266940:KRAD_RS06765
uniprot id: A6W6C0
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS09735
gene id: 266940:KRAD_RS09735
uniprot id: A6W4N8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

266940:KRAD RS02845
gene id: 266940:KRAD_RS02845
uniprot id: A6W8I7
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS05930
gene id: 266940:KRAD_RS05930
uniprot id: A6W6T6
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

266940:KRAD RS17510
gene id: 266940:KRAD_RS17510
uniprot id: A6WD72
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS21615
gene id: 266940:KRAD_RS21615
uniprot id: A6WAW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

266940:KRAD RS06295
gene id: 266940:KRAD_RS06295
uniprot id: A6W6L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS22955
gene id: 266940:KRAD_RS22955
uniprot id: A6WGS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

266940:KRAD RS03325
gene id: 266940:KRAD_RS03325
uniprot id: A6W893
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

266940:KRAD RS04715
gene id: 266940:KRAD_RS04715
uniprot id: A6W7H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

266940:KRAD RS22245
gene id: 266940:KRAD_RS22245
uniprot id: A6WAH8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

266940:KRAD RS15750
gene id: 266940:KRAD_RS15750
uniprot id: A6WE61
names: Subcellular Location Annotation
messages: Cytoplasm

266940:KRAD RS27660
gene id: 266940:KRAD_RS27660
uniprot id: A6WDC6
names: Similarity
messages: Belongs to the EfeM/EfeO family.

266940:KRAD RS19090
gene id: 266940:KRAD_RS19090
uniprot id: A6WCB5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS17675
gene id: 266940:KRAD_RS17675
uniprot id: A6WD39
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS12925
gene id: 266940:KRAD_RS12925
uniprot id: A6WFQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

266940:KRAD RS18025
gene id: 266940:KRAD_RS18025
uniprot id: A6WCW9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

266940:KRAD RS07600
gene id: 266940:KRAD_RS07600
uniprot id: A6W5V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

266940:KRAD RS03955
gene id: 266940:KRAD_RS03955
uniprot id: A6W7W9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

266940:KRAD RS04090
gene id: 266940:KRAD_RS04090
uniprot id: A6W7U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

266940:KRAD RS06075
gene id: 266940:KRAD_RS06075
uniprot id: A6W6Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

266940:KRAD RS19435
gene id: 266940:KRAD_RS19435
uniprot id: A6WC48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

266940:KRAD RS04405
gene id: 266940:KRAD_RS04405
uniprot id: A6W7N3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS15030
gene id: 266940:KRAD_RS15030
uniprot id: A6WEK2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

266940:KRAD RS03935
gene id: 266940:KRAD_RS03935
uniprot id: A6W7X3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

266940:KRAD RS07545
gene id: 266940:KRAD_RS07545
uniprot id: A6W5W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

266940:KRAD RS03545
gene id: 266940:KRAD_RS03545
uniprot id: A6W850
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS08565
gene id: 266940:KRAD_RS08565
uniprot id: A6W5B1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

266940:KRAD RS11415
gene id: 266940:KRAD_RS11415
uniprot id: A6WGI9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

266940:KRAD RS10900
gene id: 266940:KRAD_RS10900
uniprot id: A6W410
names: Similarity
messages: Belongs to the asparaginase 1 family.

266940:KRAD RS06445
gene id: 266940:KRAD_RS06445
uniprot id: A6W6I5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

266940:KRAD RS19720
gene id: 266940:KRAD_RS19720
uniprot id: A6WBZ4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

266940:KRAD RS03675
gene id: 266940:KRAD_RS03675
uniprot id: A6W826
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.

266940:KRAD RS01390
gene id: 266940:KRAD_RS01390
uniprot id: A6W9D2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

266940:KRAD RS21410
gene id: 266940:KRAD_RS21410
uniprot id: A6WB10
names: Similarity
messages: Belongs to the cytochrome P450 family.

266940:KRAD RS04805
gene id: 266940:KRAD_RS04805
uniprot id: A6W7F6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

266940:KRAD RS19535
gene id: 266940:KRAD_RS19535
uniprot id: A6WC28
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

266940:KRAD RS20935
gene id: 266940:KRAD_RS20935
uniprot id: A6WBA5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

266940:KRAD RS19125
gene id: 266940:KRAD_RS19125
uniprot id: A6WCA8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

266940:KRAD RS14075
gene id: 266940:KRAD_RS14075
uniprot id: A6WF36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS19485
gene id: 266940:KRAD_RS19485
uniprot id: A6WC38
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS08820
gene id: 266940:KRAD_RS08820
uniprot id: A6W567
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

266940:KRAD RS12755
gene id: 266940:KRAD_RS12755
uniprot id: A6WFU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

266940:KRAD RS16510
gene id: 266940:KRAD_RS16510
uniprot id: A6WDR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

266940:KRAD RS01755
gene id: 266940:KRAD_RS01755
uniprot id: A6W959
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS24180
gene id: 266940:KRAD_RS24180
uniprot id: A6W4V5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

266940:KRAD RS19265
gene id: 266940:KRAD_RS19265
uniprot id: A6WC82
names: Similarity
messages: Belongs to the leucine-binding protein family.

266940:KRAD RS05015
gene id: 266940:KRAD_RS05015
uniprot id: A6W7B5
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS13985
gene id: 266940:KRAD_RS13985
uniprot id: A6WF53
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

266940:KRAD RS01475
gene id: 266940:KRAD_RS01475
uniprot id: A6W9B5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

266940:KRAD RS13020
gene id: 266940:KRAD_RS13020
uniprot id: A6WFN7
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

266940:KRAD RS08350
gene id: 266940:KRAD_RS08350
uniprot id: A6W5F3
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS16435
gene id: 266940:KRAD_RS16435
uniprot id: A6WDS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

266940:KRAD RS14485
gene id: 266940:KRAD_RS14485
uniprot id: A6WEV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

266940:KRAD RS06090
gene id: 266940:KRAD_RS06090
uniprot id: A6W6Q3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

266940:KRAD RS10960
gene id: 266940:KRAD_RS10960
uniprot id: A6W3Z8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

266940:KRAD RS05745
gene id: 266940:KRAD_RS05745
uniprot id: A6W6X2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

266940:KRAD RS20165
gene id: 266940:KRAD_RS20165
uniprot id: A6WBQ9
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS04765
gene id: 266940:KRAD_RS04765
uniprot id: A6W7G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

266940:KRAD RS06625
gene id: 266940:KRAD_RS06625
uniprot id: A6W6E9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

266940:KRAD RS06735
gene id: 266940:KRAD_RS06735
uniprot id: A6W6C6
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

266940:KRAD RS16625
gene id: 266940:KRAD_RS16625
uniprot id: A6WDP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS12670
gene id: 266940:KRAD_RS12670
uniprot id: A6WFV7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

266940:KRAD RS03975
gene id: 266940:KRAD_RS03975
uniprot id: A6W7W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

266940:KRAD RS18650
gene id: 266940:KRAD_RS18650
uniprot id: A6WCJ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

266940:KRAD RS02775
gene id: 266940:KRAD_RS02775
uniprot id: A6W8K2
names: Similarity
messages: Belongs to the peptidase C40 family.
messages: Belongs to the transglycosylase Slt family.

266940:KRAD RS16535
gene id: 266940:KRAD_RS16535
uniprot id: A6WDR0
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

266940:KRAD RS09035
gene id: 266940:KRAD_RS09035
uniprot id: A6W523
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

266940:KRAD RS04005
gene id: 266940:KRAD_RS04005
uniprot id: A6W7V9
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

266940:KRAD RS00405
gene id: 266940:KRAD_RS00405
uniprot id: A6W9Y1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

266940:KRAD RS01605
gene id: 266940:KRAD_RS01605
uniprot id: A6W989
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

266940:KRAD RS09770
gene id: 266940:KRAD_RS09770
uniprot id: A6W4N1
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS18885
gene id: 266940:KRAD_RS18885
uniprot id: A6WCF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

266940:KRAD RS06710
gene id: 266940:KRAD_RS06710
uniprot id: A6W6D2
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

266940:KRAD RS20465
gene id: 266940:KRAD_RS20465
uniprot id: A6WBK0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

266940:KRAD RS10980
gene id: 266940:KRAD_RS10980
uniprot id: A6W3Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

266940:KRAD RS27555
gene id: 266940:KRAD_RS27555
uniprot id: A6WFP4
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

266940:KRAD RS16885
gene id: 266940:KRAD_RS16885
uniprot id: A6WDJ2
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS08825
gene id: 266940:KRAD_RS08825
uniprot id: A6W566
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

266940:KRAD RS04825
gene id: 266940:KRAD_RS04825
uniprot id: A6W7F2
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

266940:KRAD RS10570
gene id: 266940:KRAD_RS10570
uniprot id: A6W475
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

266940:KRAD RS02075
gene id: 266940:KRAD_RS02075
uniprot id: A6W8Z6
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

266940:KRAD RS15815
gene id: 266940:KRAD_RS15815
uniprot id: A6WE48
names: Similarity
messages: Belongs to the WXG100 family.

266940:KRAD RS07725
gene id: 266940:KRAD_RS07725
uniprot id: A6W5S6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

266940:KRAD RS04175
gene id: 266940:KRAD_RS04175
uniprot id: A6W7S6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

266940:KRAD RS05845
gene id: 266940:KRAD_RS05845
uniprot id: A6W6V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

266940:KRAD RS13425
gene id: 266940:KRAD_RS13425
uniprot id: A6WFF8
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

266940:KRAD RS00215
gene id: 266940:KRAD_RS00215
uniprot id: A6WA21
names: Similarity
messages: Belongs to the peptidase M20A family.

266940:KRAD RS12335
gene id: 266940:KRAD_RS12335
uniprot id: A6WG21
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

266940:KRAD RS09010
gene id: 266940:KRAD_RS09010
uniprot id: A6W529
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

266940:KRAD RS02710
gene id: 266940:KRAD_RS02710
uniprot id: A6W8L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

266940:KRAD RS17255
gene id: 266940:KRAD_RS17255
uniprot id: A6WDC1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

266940:KRAD RS03730
gene id: 266940:KRAD_RS03730
uniprot id: A6W815
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

266940:KRAD RS21415
gene id: 266940:KRAD_RS21415
uniprot id: A6WB09
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

266940:KRAD RS18745
gene id: 266940:KRAD_RS18745
uniprot id: A6WCI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

266940:KRAD RS07480
gene id: 266940:KRAD_RS07480
uniprot id: A6W5X6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS07700
gene id: 266940:KRAD_RS07700
uniprot id: A6W5T1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

266940:KRAD RS01930
gene id: 266940:KRAD_RS01930
uniprot id: A6W924
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS22885
gene id: 266940:KRAD_RS22885
uniprot id: A6WGR1
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

266940:KRAD RS07625
gene id: 266940:KRAD_RS07625
uniprot id: A6W5U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

266940:KRAD RS08935
gene id: 266940:KRAD_RS08935
uniprot id: A6W543
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

266940:KRAD RS15280
gene id: 266940:KRAD_RS15280
uniprot id: A6WEF3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

266940:KRAD RS13905
gene id: 266940:KRAD_RS13905
uniprot id: A6WF69
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

266940:KRAD RS11180
gene id: 266940:KRAD_RS11180
uniprot id: A6W3V6
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

266940:KRAD RS05715
gene id: 266940:KRAD_RS05715
uniprot id: A6W6X8
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

266940:KRAD RS19030
gene id: 266940:KRAD_RS19030
uniprot id: A6WCC7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

266940:KRAD RS17405
gene id: 266940:KRAD_RS17405
uniprot id: A6WD92
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

266940:KRAD RS17520
gene id: 266940:KRAD_RS17520
uniprot id: A6WD70
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

266940:KRAD RS07950
gene id: 266940:KRAD_RS07950
uniprot id: A6W5N6
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS20415
gene id: 266940:KRAD_RS20415
uniprot id: A6WBL0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

266940:KRAD RS11345
gene id: 266940:KRAD_RS11345
uniprot id: A6WGK3
names: Cofactor
messages: Binds 1 FAD per subunit.

266940:KRAD RS11510
gene id: 266940:KRAD_RS11510
uniprot id: A6WGH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

266940:KRAD RS04625
gene id: 266940:KRAD_RS04625
uniprot id: A6W7J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS14940
gene id: 266940:KRAD_RS14940
uniprot id: A6WEL9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

266940:KRAD RS12575
gene id: 266940:KRAD_RS12575
uniprot id: A6WFX4
names: Similarity
messages: Belongs to the thymidine kinase family.

266940:KRAD RS03535
gene id: 266940:KRAD_RS03535
uniprot id: A6W852
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

266940:KRAD RS17960
gene id: 266940:KRAD_RS17960
uniprot id: A6WCY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

266940:KRAD RS15755
gene id: 266940:KRAD_RS15755
uniprot id: A6WE60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

266940:KRAD RS21535
gene id: 266940:KRAD_RS21535
uniprot id: A6WAX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

266940:KRAD RS12150
gene id: 266940:KRAD_RS12150
uniprot id: A6WG58
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS01370
gene id: 266940:KRAD_RS01370
uniprot id: A6W9D6
names: Similarity
messages: Belongs to the CapA family.

266940:KRAD RS06570
gene id: 266940:KRAD_RS06570
uniprot id: A6W6G0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

266940:KRAD RS08760
gene id: 266940:KRAD_RS08760
uniprot id: A6W576
names: Similarity
messages: Belongs to the class-D beta-lactamase family.

266940:KRAD RS16050
gene id: 266940:KRAD_RS16050
uniprot id: A6WE01
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

266940:KRAD RS19140
gene id: 266940:KRAD_RS19140
uniprot id: A6WCA5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

266940:KRAD RS04035
gene id: 266940:KRAD_RS04035
uniprot id: A6W7V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

266940:KRAD RS03560
gene id: 266940:KRAD_RS03560
uniprot id: A6W848
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

266940:KRAD RS10125
gene id: 266940:KRAD_RS10125
uniprot id: A6W4G3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

266940:KRAD RS13125
gene id: 266940:KRAD_RS13125
uniprot id: A6WFL6
names: Similarity
messages: Belongs to the YciI family.

266940:KRAD RS15085
gene id: 266940:KRAD_RS15085
uniprot id: A6WEJ1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

266940:KRAD RS26415
gene id: 266940:KRAD_RS26415
uniprot id: A6W4M9
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS19340
gene id: 266940:KRAD_RS19340
uniprot id: A6WC67
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

266940:KRAD RS09690
gene id: 266940:KRAD_RS09690
uniprot id: A6W4P5
names: Similarity
messages: Belongs to the FPG family.

266940:KRAD RS15050
gene id: 266940:KRAD_RS15050
uniprot id: A6WEJ8
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

266940:KRAD RS14570
gene id: 266940:KRAD_RS14570
uniprot id: A6WET8
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS06530
gene id: 266940:KRAD_RS06530
uniprot id: A6W6G8
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

266940:KRAD RS00655
gene id: 266940:KRAD_RS00655
uniprot id: A6W9T2
names: Similarity
messages: Belongs to the FGGY kinase family.

266940:KRAD RS22350
gene id: 266940:KRAD_RS22350
uniprot id: A6WAF2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

266940:KRAD RS04335
gene id: 266940:KRAD_RS04335
uniprot id: A6W7P7
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS16645
gene id: 266940:KRAD_RS16645
uniprot id: A6WDN8
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

266940:KRAD RS03740
gene id: 266940:KRAD_RS03740
uniprot id: A6W813
names: Similarity
messages: Belongs to the ribF family.

266940:KRAD RS10555
gene id: 266940:KRAD_RS10555
uniprot id: A6W478
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

266940:KRAD RS00375
gene id: 266940:KRAD_RS00375
uniprot id: A6W9Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS00710
gene id: 266940:KRAD_RS00710
uniprot id: A6W9S1
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

266940:KRAD RS13535
gene id: 266940:KRAD_RS13535
uniprot id: A6WFD6
names: Similarity
messages: Belongs to the UPF0303 family.

266940:KRAD RS07880
gene id: 266940:KRAD_RS07880
uniprot id: A6W5P9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

266940:KRAD RS06210
gene id: 266940:KRAD_RS06210
uniprot id: A6W6N0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

266940:KRAD RS20275
gene id: 266940:KRAD_RS20275
uniprot id: A6WBN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

266940:KRAD RS14760
gene id: 266940:KRAD_RS14760
uniprot id: A6WEQ0
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS14080
gene id: 266940:KRAD_RS14080
uniprot id: A6WF35
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

266940:KRAD RS07270
gene id: 266940:KRAD_RS07270
uniprot id: A6W616
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

266940:KRAD RS12020
gene id: 266940:KRAD_RS12020
uniprot id: A6WG84
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS14190
gene id: 266940:KRAD_RS14190
uniprot id: A6WF14
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

266940:KRAD RS03335
gene id: 266940:KRAD_RS03335
uniprot id: A6W891
names: Similarity
messages: Belongs to the peptidase M20A family.

266940:KRAD RS14150
gene id: 266940:KRAD_RS14150
uniprot id: A6WF21
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS04295
gene id: 266940:KRAD_RS04295
uniprot id: A6W7Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

266940:KRAD RS13900
gene id: 266940:KRAD_RS13900
uniprot id: A6WF70
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS04180
gene id: 266940:KRAD_RS04180
uniprot id: A6W7S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

266940:KRAD RS24345
gene id: 266940:KRAD_RS24345
uniprot id: A6WGB5
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

266940:KRAD RS18225
gene id: 266940:KRAD_RS18225
uniprot id: A6WCS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

266940:KRAD RS07670
gene id: 266940:KRAD_RS07670
uniprot id: A6W5T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

266940:KRAD RS05055
gene id: 266940:KRAD_RS05055
uniprot id: A6W7A8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

266940:KRAD RS24795
gene id: 266940:KRAD_RS24795
uniprot id: A6WA82
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS05480
gene id: 266940:KRAD_RS05480
uniprot id: A6W723
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

266940:KRAD RS13540
gene id: 266940:KRAD_RS13540
uniprot id: A6WFD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

266940:KRAD RS15260
gene id: 266940:KRAD_RS15260
uniprot id: A6WEF7
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

266940:KRAD RS18060
gene id: 266940:KRAD_RS18060
uniprot id: A6WCW2
names: Subcellular Location Annotation
messages: Cytoplasm

266940:KRAD RS17165
gene id: 266940:KRAD_RS17165
uniprot id: A6WDD6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

266940:KRAD RS16300
gene id: 266940:KRAD_RS16300
uniprot id: A6WDV3
names: Similarity
messages: Belongs to the disproportionating enzyme family.

266940:KRAD RS07485
gene id: 266940:KRAD_RS07485
uniprot id: A6W5X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

266940:KRAD RS13505
gene id: 266940:KRAD_RS13505
uniprot id: A6WFE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

266940:KRAD RS02120
gene id: 266940:KRAD_RS02120
uniprot id: A6W8Y7
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

266940:KRAD RS04150
gene id: 266940:KRAD_RS04150
uniprot id: A6W7T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

266940:KRAD RS14010
gene id: 266940:KRAD_RS14010
uniprot id: A6WF48
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS08175
gene id: 266940:KRAD_RS08175
uniprot id: A6W5J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS04835
gene id: 266940:KRAD_RS04835
uniprot id: A6W7F0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

266940:KRAD RS14300
gene id: 266940:KRAD_RS14300
uniprot id: A6WEZ2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

266940:KRAD RS01905
gene id: 266940:KRAD_RS01905
uniprot id: A6W929
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

266940:KRAD RS10970
gene id: 266940:KRAD_RS10970
uniprot id: A6W3Z6
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS12175
gene id: 266940:KRAD_RS12175
uniprot id: A6WG53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

266940:KRAD RS01690
gene id: 266940:KRAD_RS01690
uniprot id: A6W972
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

266940:KRAD RS09970
gene id: 266940:KRAD_RS09970
uniprot id: A6W4J1
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS12885
gene id: 266940:KRAD_RS12885
uniprot id: A6WFR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS14530
gene id: 266940:KRAD_RS14530
uniprot id: A6WEU6
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS12490
gene id: 266940:KRAD_RS12490
uniprot id: A6WFZ1
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

266940:KRAD RS09750
gene id: 266940:KRAD_RS09750
uniprot id: A6W4N5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

266940:KRAD RS16945
gene id: 266940:KRAD_RS16945
uniprot id: A6WDI0
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

266940:KRAD RS10395
gene id: 266940:KRAD_RS10395
uniprot id: A6W4B0
names: Similarity
messages: Belongs to the FPG family.

266940:KRAD RS06870
gene id: 266940:KRAD_RS06870
uniprot id: A6W699
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

266940:KRAD RS06285
gene id: 266940:KRAD_RS06285
uniprot id: A6W6L5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

266940:KRAD RS04890
gene id: 266940:KRAD_RS04890
uniprot id: A6W7E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

266940:KRAD RS02040
gene id: 266940:KRAD_RS02040
uniprot id: A6W902
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

266940:KRAD RS19230
gene id: 266940:KRAD_RS19230
uniprot id: A6WC87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

266940:KRAD RS07655
gene id: 266940:KRAD_RS07655
uniprot id: A6W5U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

266940:KRAD RS18795
gene id: 266940:KRAD_RS18795
uniprot id: A6WCH3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

266940:KRAD RS21510
gene id: 266940:KRAD_RS21510
uniprot id: A6WAY5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

266940:KRAD RS27650
gene id: 266940:KRAD_RS27650
uniprot id: A6WDX6
names: Similarity
messages: Belongs to the peptidase C40 family.

266940:KRAD RS15175
gene id: 266940:KRAD_RS15175
uniprot id: A6WEH4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

266940:KRAD RS17175
gene id: 266940:KRAD_RS17175
uniprot id: A6WDD5
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

266940:KRAD RS11200
gene id: 266940:KRAD_RS11200
uniprot id: A6WGN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

266940:KRAD RS14380
gene id: 266940:KRAD_RS14380
uniprot id: A6WEX6
names: Similarity
messages: Belongs to the peptidase S8 family.

266940:KRAD RS07565
gene id: 266940:KRAD_RS07565
uniprot id: A6W5V9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

266940:KRAD RS12370
gene id: 266940:KRAD_RS12370
uniprot id: A6WG15
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

266940:KRAD RS01680
gene id: 266940:KRAD_RS01680
uniprot id: A6W974
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

266940:KRAD RS19440
gene id: 266940:KRAD_RS19440
uniprot id: A6WC47
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

266940:KRAD RS17515
gene id: 266940:KRAD_RS17515
uniprot id: A6WD71
names: Similarity
messages: Belongs to the glutamine synthetase family.

266940:KRAD RS18410
gene id: 266940:KRAD_RS18410
uniprot id: A6WCP5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

266940:KRAD RS17750
gene id: 266940:KRAD_RS17750
uniprot id: A6WD24
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS11195
gene id: 266940:KRAD_RS11195
uniprot id: A6WGN3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

266940:KRAD RS01410
gene id: 266940:KRAD_RS01410
uniprot id: A6W9C8
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

266940:KRAD RS13485
gene id: 266940:KRAD_RS13485
uniprot id: A6WFE6
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

266940:KRAD RS11605
gene id: 266940:KRAD_RS11605
uniprot id: A6WGF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

266940:KRAD RS02745
gene id: 266940:KRAD_RS02745
uniprot id: A6W8K8
names: Similarity
messages: Belongs to the MotB family.

266940:KRAD RS13380
gene id: 266940:KRAD_RS13380
uniprot id: A6WFG7
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS00305
gene id: 266940:KRAD_RS00305
uniprot id: A6WA02
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

266940:KRAD RS12705
gene id: 266940:KRAD_RS12705
uniprot id: A6WFV0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

266940:KRAD RS03820
gene id: 266940:KRAD_RS03820
uniprot id: A6W7Z6
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS09740
gene id: 266940:KRAD_RS09740
uniprot id: A6W4N7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

266940:KRAD RS19475
gene id: 266940:KRAD_RS19475
uniprot id: A6WC40
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

266940:KRAD RS13105
gene id: 266940:KRAD_RS13105
uniprot id: A6WFM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS03620
gene id: 266940:KRAD_RS03620
uniprot id: A6W837
names: Similarity
messages: Belongs to the FPG family.

266940:KRAD RS07200
gene id: 266940:KRAD_RS07200
uniprot id: A6W630
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

266940:KRAD RS23025
gene id: 266940:KRAD_RS23025
uniprot id: A6WGU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

266940:KRAD RS11500
gene id: 266940:KRAD_RS11500
uniprot id: A6WGH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

266940:KRAD RS07845
gene id: 266940:KRAD_RS07845
uniprot id: A6W5Q6
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

266940:KRAD RS16630
gene id: 266940:KRAD_RS16630
uniprot id: A6WDP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS14835
gene id: 266940:KRAD_RS14835
uniprot id: A6WEN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

266940:KRAD RS12240
gene id: 266940:KRAD_RS12240
uniprot id: A6WG40
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

266940:KRAD RS12890
gene id: 266940:KRAD_RS12890
uniprot id: A6WFR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS19040
gene id: 266940:KRAD_RS19040
uniprot id: A6WCC5
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

266940:KRAD RS01695
gene id: 266940:KRAD_RS01695
uniprot id: A6W971
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

266940:KRAD RS00750
gene id: 266940:KRAD_RS00750
uniprot id: A6W9R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

266940:KRAD RS22945
gene id: 266940:KRAD_RS22945
uniprot id: A6WGS4
names: Similarity
messages: Belongs to the peptidase C40 family.

266940:KRAD RS07755
gene id: 266940:KRAD_RS07755
uniprot id: A6W5S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

266940:KRAD RS16940
gene id: 266940:KRAD_RS16940
uniprot id: A6WDI1
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

266940:KRAD RS02950
gene id: 266940:KRAD_RS02950
uniprot id: A6W8G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

266940:KRAD RS12995
gene id: 266940:KRAD_RS12995
uniprot id: A6WFP2
names: Similarity
messages: Belongs to the fatty acyl-CoA reductase family.

266940:KRAD RS12785
gene id: 266940:KRAD_RS12785
uniprot id: A6WFT4
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS07680
gene id: 266940:KRAD_RS07680
uniprot id: A6W5T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

266940:KRAD RS18000
gene id: 266940:KRAD_RS18000
uniprot id: A6WCX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS12450
gene id: 266940:KRAD_RS12450
uniprot id: A6WFZ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

266940:KRAD RS17650
gene id: 266940:KRAD_RS17650
uniprot id: A6WD44
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS06675
gene id: 266940:KRAD_RS06675
uniprot id: A6W6D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

266940:KRAD RS22870
gene id: 266940:KRAD_RS22870
uniprot id: A6WGQ8
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

266940:KRAD RS09230
gene id: 266940:KRAD_RS09230
uniprot id: A6W4Y4
names: Similarity
messages: Belongs to the peptidase S8 family.

266940:KRAD RS14165
gene id: 266940:KRAD_RS14165
uniprot id: A6WF18
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

266940:KRAD RS03930
gene id: 266940:KRAD_RS03930
uniprot id: A6W7X4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

266940:KRAD RS04840
gene id: 266940:KRAD_RS04840
uniprot id: A6W7E9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

266940:KRAD RS02750
gene id: 266940:KRAD_RS02750
uniprot id: A6W8K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

266940:KRAD RS02840
gene id: 266940:KRAD_RS02840
uniprot id: A6W8I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

266940:KRAD RS19450
gene id: 266940:KRAD_RS19450
uniprot id: A6WC45
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS06855
gene id: 266940:KRAD_RS06855
uniprot id: A6W6A2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

266940:KRAD RS10455
gene id: 266940:KRAD_RS10455
uniprot id: A6W498
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

266940:KRAD RS16235
gene id: 266940:KRAD_RS16235
uniprot id: A6WDW6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

266940:KRAD RS19185
gene id: 266940:KRAD_RS19185
uniprot id: A6WC96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

266940:KRAD RS07240
gene id: 266940:KRAD_RS07240
uniprot id: A6W622
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS14280
gene id: 266940:KRAD_RS14280
uniprot id: A6WEZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

266940:KRAD RS20785
gene id: 266940:KRAD_RS20785
uniprot id: A6WBD5
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS16430
gene id: 266940:KRAD_RS16430
uniprot id: A6WDS9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

266940:KRAD RS14700
gene id: 266940:KRAD_RS14700
uniprot id: A6WER2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

266940:KRAD RS06745
gene id: 266940:KRAD_RS06745
uniprot id: A6W6C4
names: Similarity
messages: Belongs to the PstS family.

266940:KRAD RS09135
gene id: 266940:KRAD_RS09135
uniprot id: A6W503
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

266940:KRAD RS15155
gene id: 266940:KRAD_RS15155
uniprot id: A6WEH8
names: Similarity
messages: Belongs to the cytochrome P450 family.

266940:KRAD RS07345
gene id: 266940:KRAD_RS07345
uniprot id: A6W602
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

266940:KRAD RS00040
gene id: 266940:KRAD_RS00040
uniprot id: A6WA58
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

266940:KRAD RS10000
gene id: 266940:KRAD_RS10000
uniprot id: A6W4I5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

266940:KRAD RS04760
gene id: 266940:KRAD_RS04760
uniprot id: A6W7G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

266940:KRAD RS03965
gene id: 266940:KRAD_RS03965
uniprot id: A6W7W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

266940:KRAD RS05365
gene id: 266940:KRAD_RS05365
uniprot id: A6W746
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

266940:KRAD RS08440
gene id: 266940:KRAD_RS08440
uniprot id: A6W5D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

266940:KRAD RS10040
gene id: 266940:KRAD_RS10040
uniprot id: A6W4H8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

266940:KRAD RS14070
gene id: 266940:KRAD_RS14070
uniprot id: A6WF37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS20435
gene id: 266940:KRAD_RS20435
uniprot id: A6WBK6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

266940:KRAD RS10080
gene id: 266940:KRAD_RS10080
uniprot id: A6W4H0
names: Subcellular Location Annotation
messages: Cytoplasm

266940:KRAD RS16980
gene id: 266940:KRAD_RS16980
uniprot id: A6WDH3
names: Similarity
messages: Belongs to the asparagine synthetase family.

266940:KRAD RS06685
gene id: 266940:KRAD_RS06685
uniprot id: A6W6D7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

266940:KRAD RS05495
gene id: 266940:KRAD_RS05495
uniprot id: A6W720
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

266940:KRAD RS09985
gene id: 266940:KRAD_RS09985
uniprot id: A6W4I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

266940:KRAD RS03890
gene id: 266940:KRAD_RS03890
uniprot id: A6W7Y2
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

266940:KRAD RS18270
gene id: 266940:KRAD_RS18270
uniprot id: A6WCS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS00295
gene id: 266940:KRAD_RS00295
uniprot id: A6WA04
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

266940:KRAD RS19430
gene id: 266940:KRAD_RS19430
uniprot id: A6WC49
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS19035
gene id: 266940:KRAD_RS19035
uniprot id: A6WCC6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

266940:KRAD RS11770
gene id: 266940:KRAD_RS11770
uniprot id: A6WGC4
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS05440
gene id: 266940:KRAD_RS05440
uniprot id: A6W731
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

266940:KRAD RS04745
gene id: 266940:KRAD_RS04745
uniprot id: A6W7G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

266940:KRAD RS02720
gene id: 266940:KRAD_RS02720
uniprot id: A6W8L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

266940:KRAD RS06485
gene id: 266940:KRAD_RS06485
uniprot id: A6W6H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

266940:KRAD RS19210
gene id: 266940:KRAD_RS19210
uniprot id: A6WC91
names: Similarity
messages: Belongs to the TrpC family.

266940:KRAD RS10400
gene id: 266940:KRAD_RS10400
uniprot id: A6W4A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

266940:KRAD RS16490
gene id: 266940:KRAD_RS16490
uniprot id: A6WDR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

266940:KRAD RS09860
gene id: 266940:KRAD_RS09860
uniprot id: A6W4L3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

266940:KRAD RS02225
gene id: 266940:KRAD_RS02225
uniprot id: A6W8W3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

266940:KRAD RS06525
gene id: 266940:KRAD_RS06525
uniprot id: A6W6G9
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

266940:KRAD RS09130
gene id: 266940:KRAD_RS09130
uniprot id: A6W504
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

266940:KRAD RS04980
gene id: 266940:KRAD_RS04980
uniprot id: A6W7C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

266940:KRAD RS17635
gene id: 266940:KRAD_RS17635
uniprot id: A6WD47
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

266940:KRAD RS17670
gene id: 266940:KRAD_RS17670
uniprot id: A6WD40
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

266940:KRAD RS15875
gene id: 266940:KRAD_RS15875
uniprot id: A6WE36
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent 3'-5' DNA helicase, unwinds 3'-overhangs, 3'- flaps, and splayed-arm DNA substrates but not 5'-overhangs or 5'-flap substrates. Requires ATP hydrolysis for activity; the ATPase activity is DNA-dependent and requires a minimum of 4 single-stranded nucleotides (nt) with 6-10 nt providing all necessary interactions for full processive unwinding. The ATPase prefers ATP over CTP or GTP, is almost inactive with TTP.
messages: ATPase activity has a small preference for Mn(2+) over Mg(2+) or Ca(2+). Co(2+) and Zn(2+) are inactive.
messages: Belongs to the helicase family. RAD25/XPB subfamily.
messages: Monomer.
messages: Removal of the N-terminus decreases solubility and/or structural integrity of the protein.

266940:KRAD RS20565
gene id: 266940:KRAD_RS20565
uniprot id: A6WBI1
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS16695
gene id: 266940:KRAD_RS16695
uniprot id: A6WDM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

266940:KRAD RS03795
gene id: 266940:KRAD_RS03795
uniprot id: A6W801
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

266940:KRAD RS17540
gene id: 266940:KRAD_RS17540
uniprot id: A6WD66
names: Similarity
messages: Belongs to the glutamine synthetase family.

266940:KRAD RS00625
gene id: 266940:KRAD_RS00625
uniprot id: A6W9T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS16605
gene id: 266940:KRAD_RS16605
uniprot id: A6WDP6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

266940:KRAD RS26535
gene id: 266940:KRAD_RS26535
uniprot id: A6W652
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

266940:KRAD RS16690
gene id: 266940:KRAD_RS16690
uniprot id: A6WDM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

266940:KRAD RS23675
gene id: 266940:KRAD_RS23675
uniprot id: A6WH76
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

266940:KRAD RS06245
gene id: 266940:KRAD_RS06245
uniprot id: A6W6M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS19390
gene id: 266940:KRAD_RS19390
uniprot id: A6WC57
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

266940:KRAD RS04230
gene id: 266940:KRAD_RS04230
uniprot id: A6W7R5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

266940:KRAD RS00440
gene id: 266940:KRAD_RS00440
uniprot id: A6W9X5
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS15305
gene id: 266940:KRAD_RS15305
uniprot id: A6WEE8
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS21150
gene id: 266940:KRAD_RS21150
uniprot id: A6WB59
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

266940:KRAD RS15025
gene id: 266940:KRAD_RS15025
uniprot id: A6WEK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

266940:KRAD RS16115
gene id: 266940:KRAD_RS16115
uniprot id: A6WDY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS06915
gene id: 266940:KRAD_RS06915
uniprot id: A6W689
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS02935
gene id: 266940:KRAD_RS02935
uniprot id: A6W8G9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

266940:KRAD RS05530
gene id: 266940:KRAD_RS05530
uniprot id: A6W713
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS11660
gene id: 266940:KRAD_RS11660
uniprot id: A6WGE4
names: Similarity
messages: Belongs to the glutamine synthetase family.

266940:KRAD RS06655
gene id: 266940:KRAD_RS06655
uniprot id: A6W6E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

266940:KRAD RS07510
gene id: 266940:KRAD_RS07510
uniprot id: A6W5X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

266940:KRAD RS06670
gene id: 266940:KRAD_RS06670
uniprot id: A6W6E0
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

266940:KRAD RS02730
gene id: 266940:KRAD_RS02730
uniprot id: A6W8L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

266940:KRAD RS06150
gene id: 266940:KRAD_RS06150
uniprot id: A6W6P1
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

266940:KRAD RS17125
gene id: 266940:KRAD_RS17125
uniprot id: A6WDE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

266940:KRAD RS07550
gene id: 266940:KRAD_RS07550
uniprot id: A6W5W2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

266940:KRAD RS19400
gene id: 266940:KRAD_RS19400
uniprot id: A6WC55
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

266940:KRAD RS06070
gene id: 266940:KRAD_RS06070
uniprot id: A6W6Q7
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

266940:KRAD RS04050
gene id: 266940:KRAD_RS04050
uniprot id: A6W7V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

266940:KRAD RS06835
gene id: 266940:KRAD_RS06835
uniprot id: A6W6A6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

266940:KRAD RS04265
gene id: 266940:KRAD_RS04265
uniprot id: A6W7Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

266940:KRAD RS06715
gene id: 266940:KRAD_RS06715
uniprot id: A6W6D1
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

266940:KRAD RS09595
gene id: 266940:KRAD_RS09595
uniprot id: A6W4R4
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

266940:KRAD RS03660
gene id: 266940:KRAD_RS03660
uniprot id: A6W829
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

266940:KRAD RS10870
gene id: 266940:KRAD_RS10870
uniprot id: A6W416
names: Subcellular Location Annotation
messages: Cytoplasm

266940:KRAD RS19420
gene id: 266940:KRAD_RS19420
uniprot id: A6WC51
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

266940:KRAD RS04425
gene id: 266940:KRAD_RS04425
uniprot id: A6W7M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

266940:KRAD RS14610
gene id: 266940:KRAD_RS14610
uniprot id: A6WET0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

266940:KRAD RS05145
gene id: 266940:KRAD_RS05145
uniprot id: A6W792
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

266940:KRAD RS18520
gene id: 266940:KRAD_RS18520
uniprot id: A6WCM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

266940:KRAD RS07245
gene id: 266940:KRAD_RS07245
uniprot id: A6W621
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

266940:KRAD RS02000
gene id: 266940:KRAD_RS02000
uniprot id: A6W910
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS05245
gene id: 266940:KRAD_RS05245
uniprot id: A6W771
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

266940:KRAD RS09555
gene id: 266940:KRAD_RS09555
uniprot id: A6W4S2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

266940:KRAD RS14110
gene id: 266940:KRAD_RS14110
uniprot id: A6WF29
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

266940:KRAD RS05905
gene id: 266940:KRAD_RS05905
uniprot id: A6W6U1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

266940:KRAD RS15995
gene id: 266940:KRAD_RS15995
uniprot id: A6WE12
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS03850
gene id: 266940:KRAD_RS03850
uniprot id: A6W7Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

266940:KRAD RS08785
gene id: 266940:KRAD_RS08785
uniprot id: A6W572
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

266940:KRAD RS03160
gene id: 266940:KRAD_RS03160
uniprot id: A6W8C5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

266940:KRAD RS15895
gene id: 266940:KRAD_RS15895
uniprot id: A6WE32
names: Similarity
messages: Belongs to the asparaginase 1 family.

266940:KRAD RS05100
gene id: 266940:KRAD_RS05100
uniprot id: A6W799
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS16140
gene id: 266940:KRAD_RS16140
uniprot id: A6WDY4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

266940:KRAD RS07690
gene id: 266940:KRAD_RS07690
uniprot id: A6W5T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

266940:KRAD RS12950
gene id: 266940:KRAD_RS12950
uniprot id: A6WFQ1
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

266940:KRAD RS13780
gene id: 266940:KRAD_RS13780
uniprot id: A6WF93
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS13455
gene id: 266940:KRAD_RS13455
uniprot id: A6WFF2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

266940:KRAD RS24835
gene id: 266940:KRAD_RS24835
uniprot id: A6WGZ2
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

266940:KRAD RS06750
gene id: 266940:KRAD_RS06750
uniprot id: A6W6C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

266940:KRAD RS04040
gene id: 266940:KRAD_RS04040
uniprot id: A6W7V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

266940:KRAD RS03405
gene id: 266940:KRAD_RS03405
uniprot id: A6W879
names: Similarity
messages: Belongs to the universal stress protein A family.

266940:KRAD RS07280
gene id: 266940:KRAD_RS07280
uniprot id: A6W614
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

266940:KRAD RS22110
gene id: 266940:KRAD_RS22110
uniprot id: A6WAK8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

266940:KRAD RS17710
gene id: 266940:KRAD_RS17710
uniprot id: A6WD32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

266940:KRAD RS12455
gene id: 266940:KRAD_RS12455
uniprot id: A6WFZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer.

266940:KRAD RS10945
gene id: 266940:KRAD_RS10945
uniprot id: A6W401
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

266940:KRAD RS17225
gene id: 266940:KRAD_RS17225
uniprot id: A6WDC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

266940:KRAD RS12130
gene id: 266940:KRAD_RS12130
uniprot id: A6WG62
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS12580
gene id: 266940:KRAD_RS12580
uniprot id: A6WFX3
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS05380
gene id: 266940:KRAD_RS05380
uniprot id: A6W743
names: Similarity
messages: Belongs to the LOG family.

266940:KRAD RS15265
gene id: 266940:KRAD_RS15265
uniprot id: A6WEF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS19495
gene id: 266940:KRAD_RS19495
uniprot id: A6WC36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

266940:KRAD RS12905
gene id: 266940:KRAD_RS12905
uniprot id: A6WFR0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS14540
gene id: 266940:KRAD_RS14540
uniprot id: A6WEU4
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

266940:KRAD RS16350
gene id: 266940:KRAD_RS16350
uniprot id: A6WDU3
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

266940:KRAD RS06300
gene id: 266940:KRAD_RS06300
uniprot id: A6W6L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS10430
gene id: 266940:KRAD_RS10430
uniprot id: A6W4A3
names: Similarity
messages: Belongs to the FPG family.

266940:KRAD RS19010
gene id: 266940:KRAD_RS19010
uniprot id: A6WCD1
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

266940:KRAD RS04445
gene id: 266940:KRAD_RS04445
uniprot id: A6W7M5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

266940:KRAD RS15075
gene id: 266940:KRAD_RS15075
uniprot id: A6WEJ3
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS10160
gene id: 266940:KRAD_RS10160
uniprot id: A6W4F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

266940:KRAD RS00055
gene id: 266940:KRAD_RS00055
uniprot id: A6WA54
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

266940:KRAD RS08630
gene id: 266940:KRAD_RS08630
uniprot id: A6W599
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

266940:KRAD RS18150
gene id: 266940:KRAD_RS18150
uniprot id: A6WCU3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

266940:KRAD RS02115
gene id: 266940:KRAD_RS02115
uniprot id: A6W8Y8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

266940:KRAD RS03580
gene id: 266940:KRAD_RS03580
uniprot id: A6W844
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

266940:KRAD RS07775
gene id: 266940:KRAD_RS07775
uniprot id: A6W5R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

266940:KRAD RS14115
gene id: 266940:KRAD_RS14115
uniprot id: A6WF28
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

266940:KRAD RS06035
gene id: 266940:KRAD_RS06035
uniprot id: A6W6R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

266940:KRAD RS11160
gene id: 266940:KRAD_RS11160
uniprot id: A6W3W0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

266940:KRAD RS06910
gene id: 266940:KRAD_RS06910
uniprot id: A6W690
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

266940:KRAD RS00730
gene id: 266940:KRAD_RS00730
uniprot id: A6W9R7
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

266940:KRAD RS01990
gene id: 266940:KRAD_RS01990
uniprot id: A6W912
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS01625
gene id: 266940:KRAD_RS01625
uniprot id: A6W985
names: Similarity
messages: Belongs to the LppX/LprAFG lipoprotein family.

266940:KRAD RS07475
gene id: 266940:KRAD_RS07475
uniprot id: A6W5X7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

266940:KRAD RS10260
gene id: 266940:KRAD_RS10260
uniprot id: A6W4D6
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS07535
gene id: 266940:KRAD_RS07535
uniprot id: A6W5W5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

266940:KRAD RS05405
gene id: 266940:KRAD_RS05405
uniprot id: A6W738
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

266940:KRAD RS12065
gene id: 266940:KRAD_RS12065
uniprot id: A6WG75
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

266940:KRAD RS07580
gene id: 266940:KRAD_RS07580
uniprot id: A6W5V6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

266940:KRAD RS12120
gene id: 266940:KRAD_RS12120
uniprot id: A6WG64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

266940:KRAD RS05275
gene id: 266940:KRAD_RS05275
uniprot id: A6W765
names: Similarity
messages: Belongs to the DEAD box helicase family.

266940:KRAD RS02735
gene id: 266940:KRAD_RS02735
uniprot id: A6W8L0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

266940:KRAD RS17505
gene id: 266940:KRAD_RS17505
uniprot id: A6WD73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

266940:KRAD RS17160
gene id: 266940:KRAD_RS17160
uniprot id: A6WDD7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

266940:KRAD RS19155
gene id: 266940:KRAD_RS19155
uniprot id: A6WCA2
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

266940:KRAD RS09775
gene id: 266940:KRAD_RS09775
uniprot id: A6W4N0
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS19725
gene id: 266940:KRAD_RS19725
uniprot id: A6WBZ3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

266940:KRAD RS11190
gene id: 266940:KRAD_RS11190
uniprot id: A6W3V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

266940:KRAD RS11570
gene id: 266940:KRAD_RS11570
uniprot id: A6WGF8
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

266940:KRAD RS14775
gene id: 266940:KRAD_RS14775
uniprot id: A6WEP7
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

266940:KRAD RS17050
gene id: 266940:KRAD_RS17050
uniprot id: A6WDF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

266940:KRAD RS09685
gene id: 266940:KRAD_RS09685
uniprot id: A6W4P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS07425
gene id: 266940:KRAD_RS07425
uniprot id: A6W5Y7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

266940:KRAD RS19275
gene id: 266940:KRAD_RS19275
uniprot id: A6WC80
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS06940
gene id: 266940:KRAD_RS06940
uniprot id: A6W684
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

266940:KRAD RS17525
gene id: 266940:KRAD_RS17525
uniprot id: A6WD69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F420-dependent glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone.
messages: Homodimer.

266940:KRAD RS07910
gene id: 266940:KRAD_RS07910
uniprot id: A6W5P3
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

266940:KRAD RS20735
gene id: 266940:KRAD_RS20735
uniprot id: A6WBE5
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS24670
gene id: 266940:KRAD_RS24670
uniprot id: A6WBB3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

266940:KRAD RS06620
gene id: 266940:KRAD_RS06620
uniprot id: A6W6F0
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS07640
gene id: 266940:KRAD_RS07640
uniprot id: A6W5U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

266940:KRAD RS07610
gene id: 266940:KRAD_RS07610
uniprot id: A6W5V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

266940:KRAD RS11470
gene id: 266940:KRAD_RS11470
uniprot id: A6WGH8
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

266940:KRAD RS22410
gene id: 266940:KRAD_RS22410
uniprot id: A6WAD6
names: Similarity
messages: Belongs to the Gfa family.

266940:KRAD RS16410
gene id: 266940:KRAD_RS16410
uniprot id: A6WDT3
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

266940:KRAD RS09830
gene id: 266940:KRAD_RS09830
uniprot id: A6W4L9
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS04350
gene id: 266940:KRAD_RS04350
uniprot id: A6W7P4
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

266940:KRAD RS18190
gene id: 266940:KRAD_RS18190
uniprot id: A6WCT5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

266940:KRAD RS03005
gene id: 266940:KRAD_RS03005
uniprot id: A6W8F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

266940:KRAD RS13700
gene id: 266940:KRAD_RS13700
uniprot id: A6WFA8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

266940:KRAD RS09680
gene id: 266940:KRAD_RS09680
uniprot id: A6W4P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS07710
gene id: 266940:KRAD_RS07710
uniprot id: A6W5S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

266940:KRAD RS05065
gene id: 266940:KRAD_RS05065
uniprot id: A6W7A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

266940:KRAD RS10490
gene id: 266940:KRAD_RS10490
uniprot id: A6W491
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

266940:KRAD RS12340
gene id: 266940:KRAD_RS12340
uniprot id: A6WG20
names: Function
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

266940:KRAD RS14855
gene id: 266940:KRAD_RS14855
uniprot id: A6WEN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

266940:KRAD RS16045
gene id: 266940:KRAD_RS16045
uniprot id: A6WE02
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

266940:KRAD RS04355
gene id: 266940:KRAD_RS04355
uniprot id: A6W7P3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

266940:KRAD RS14975
gene id: 266940:KRAD_RS14975
uniprot id: A6WEL2
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS05340
gene id: 266940:KRAD_RS05340
uniprot id: A6W752
names: Similarity
messages: Belongs to the peptidase S1C family.

266940:KRAD RS07320
gene id: 266940:KRAD_RS07320
uniprot id: A6W607
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

266940:KRAD RS04820
gene id: 266940:KRAD_RS04820
uniprot id: A6W7F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

266940:KRAD RS18345
gene id: 266940:KRAD_RS18345
uniprot id: A6WCQ8
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS24285
gene id: 266940:KRAD_RS24285
uniprot id: A6W3Y3
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

266940:KRAD RS14490
gene id: 266940:KRAD_RS14490
uniprot id: A6WEV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

266940:KRAD RS18075
gene id: 266940:KRAD_RS18075
uniprot id: A6WCV8
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

266940:KRAD RS19095
gene id: 266940:KRAD_RS19095
uniprot id: A6WCB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

266940:KRAD RS14215
gene id: 266940:KRAD_RS14215
uniprot id: A6WF09
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS14460
gene id: 266940:KRAD_RS14460
uniprot id: A6WEW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

266940:KRAD RS13975
gene id: 266940:KRAD_RS13975
uniprot id: A6WF55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

266940:KRAD RS08115
gene id: 266940:KRAD_RS08115
uniprot id: A6W5K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

266940:KRAD RS06145
gene id: 266940:KRAD_RS06145
uniprot id: A6W6P2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

266940:KRAD RS12775
gene id: 266940:KRAD_RS12775
uniprot id: A6WFT6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

266940:KRAD RS07555
gene id: 266940:KRAD_RS07555
uniprot id: A6W5W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

266940:KRAD RS03690
gene id: 266940:KRAD_RS03690
uniprot id: A6W823
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

266940:KRAD RS05210
gene id: 266940:KRAD_RS05210
uniprot id: A6W778
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

266940:KRAD RS07835
gene id: 266940:KRAD_RS07835
uniprot id: A6W5Q8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

266940:KRAD RS16915
gene id: 266940:KRAD_RS16915
uniprot id: A6WDI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

266940:KRAD RS00240
gene id: 266940:KRAD_RS00240
uniprot id: A6WA15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS15440
gene id: 266940:KRAD_RS15440
uniprot id: A6WEC4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS01540
gene id: 266940:KRAD_RS01540
uniprot id: A6W9A2
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

266940:KRAD RS11975
gene id: 266940:KRAD_RS11975
uniprot id: A6WG90
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

266940:KRAD RS12225
gene id: 266940:KRAD_RS12225
uniprot id: A6WG43
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

266940:KRAD RS16295
gene id: 266940:KRAD_RS16295
uniprot id: A6WDV4
names: Similarity
messages: Belongs to the peptidase S9A family.

266940:KRAD RS27380
gene id: 266940:KRAD_RS27380
uniprot id: A6W9U1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

266940:KRAD RS11245
gene id: 266940:KRAD_RS11245
uniprot id: A6WGM3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

266940:KRAD RS10685
gene id: 266940:KRAD_RS10685
uniprot id: A6W452
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

266940:KRAD RS12050
gene id: 266940:KRAD_RS12050
uniprot id: A6WG78
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS19085
gene id: 266940:KRAD_RS19085
uniprot id: A6WCB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

266940:KRAD RS07605
gene id: 266940:KRAD_RS07605
uniprot id: A6W5V1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

266940:KRAD RS08920
gene id: 266940:KRAD_RS08920
uniprot id: A6W546
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS22035
gene id: 266940:KRAD_RS22035
uniprot id: A6WAM3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

266940:KRAD RS16635
gene id: 266940:KRAD_RS16635
uniprot id: A6WDP0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

266940:KRAD RS14585
gene id: 266940:KRAD_RS14585
uniprot id: A6WET5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS11175
gene id: 266940:KRAD_RS11175
uniprot id: A6W3V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

266940:KRAD RS06120
gene id: 266940:KRAD_RS06120
uniprot id: A6W6P7
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

266940:KRAD RS25955
gene id: 266940:KRAD_RS25955
uniprot id: A6W521
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS04065
gene id: 266940:KRAD_RS04065
uniprot id: A6W7U7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

266940:KRAD RS17350
gene id: 266940:KRAD_RS17350
uniprot id: A6WDA3
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS14535
gene id: 266940:KRAD_RS14535
uniprot id: A6WEU5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

266940:KRAD RS14360
gene id: 266940:KRAD_RS14360
uniprot id: A6WEY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

266940:KRAD RS05435
gene id: 266940:KRAD_RS05435
uniprot id: A6W732
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

266940:KRAD RS00230
gene id: 266940:KRAD_RS00230
uniprot id: A6WA17
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

266940:KRAD RS18975
gene id: 266940:KRAD_RS18975
uniprot id: A6WCD8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS07720
gene id: 266940:KRAD_RS07720
uniprot id: A6W5S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

266940:KRAD RS04435
gene id: 266940:KRAD_RS04435
uniprot id: A6W7M7
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

266940:KRAD RS04620
gene id: 266940:KRAD_RS04620
uniprot id: A6W7J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS00735
gene id: 266940:KRAD_RS00735
uniprot id: A6W9R6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

266940:KRAD RS01175
gene id: 266940:KRAD_RS01175
uniprot id: A6W9H5
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS20130
gene id: 266940:KRAD_RS20130
uniprot id: A6WBR6
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

266940:KRAD RS08025
gene id: 266940:KRAD_RS08025
uniprot id: A6W5M1
names: Similarity
messages: Belongs to the aldose epimerase family.

266940:KRAD RS12245
gene id: 266940:KRAD_RS12245
uniprot id: A6WG39
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

266940:KRAD RS06025
gene id: 266940:KRAD_RS06025
uniprot id: A6W6R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

266940:KRAD RS16465
gene id: 266940:KRAD_RS16465
uniprot id: A6WDS2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

266940:KRAD RS02905
gene id: 266940:KRAD_RS02905
uniprot id: A6W8H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

266940:KRAD RS15100
gene id: 266940:KRAD_RS15100
uniprot id: A6WEI8
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

266940:KRAD RS15105
gene id: 266940:KRAD_RS15105
uniprot id: A6WEI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

266940:KRAD RS07330
gene id: 266940:KRAD_RS07330
uniprot id: A6W605
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS27585
gene id: 266940:KRAD_RS27585
uniprot id: A6WEQ6
names: Similarity
messages: Belongs to the peptidase S9C family.

266940:KRAD RS07780
gene id: 266940:KRAD_RS07780
uniprot id: A6W5R6
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS14820
gene id: 266940:KRAD_RS14820
uniprot id: A6WEN8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

266940:KRAD RS09705
gene id: 266940:KRAD_RS09705
uniprot id: A6W4P2
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS06440
gene id: 266940:KRAD_RS06440
uniprot id: A6W6I6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

266940:KRAD RS03745
gene id: 266940:KRAD_RS03745
uniprot id: A6W812
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

266940:KRAD RS01520
gene id: 266940:KRAD_RS01520
uniprot id: A6W9A6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS17375
gene id: 266940:KRAD_RS17375
uniprot id: A6WD98
names: Similarity
messages: Belongs to the OsmC/Ohr family.

266940:KRAD RS09085
gene id: 266940:KRAD_RS09085
uniprot id: A6W513
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

266940:KRAD RS14140
gene id: 266940:KRAD_RS14140
uniprot id: A6WF23
names: Similarity
messages: Belongs to the BMP lipoprotein family.

266940:KRAD RS18305
gene id: 266940:KRAD_RS18305
uniprot id: A6WCR6
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS17600
gene id: 266940:KRAD_RS17600
uniprot id: A6WD54
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

266940:KRAD RS20610
gene id: 266940:KRAD_RS20610
uniprot id: A6WBH2
names: Similarity
messages: Belongs to the peptidase S33 family.

266940:KRAD RS04610
gene id: 266940:KRAD_RS04610
uniprot id: A6W7J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

266940:KRAD RS05425
gene id: 266940:KRAD_RS05425
uniprot id: A6W734
names: Similarity
messages: Belongs to the AAA ATPase family.

266940:KRAD RS16155
gene id: 266940:KRAD_RS16155
uniprot id: A6WDY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

266940:KRAD RS08915
gene id: 266940:KRAD_RS08915
uniprot id: A6W547
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS21565
gene id: 266940:KRAD_RS21565
uniprot id: A6WAX3
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

266940:KRAD RS13420
gene id: 266940:KRAD_RS13420
uniprot id: A6WFF9
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

266940:KRAD RS10845
gene id: 266940:KRAD_RS10845
uniprot id: A6W421
names: Similarity
messages: Belongs to the universal stress protein A family.

266940:KRAD RS05615
gene id: 266940:KRAD_RS05615
uniprot id: A6W6Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

266940:KRAD RS12135
gene id: 266940:KRAD_RS12135
uniprot id: A6WG61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

266940:KRAD RS19115
gene id: 266940:KRAD_RS19115
uniprot id: A6WCB0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

266940:KRAD RS07500
gene id: 266940:KRAD_RS07500
uniprot id: A6W5X2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

266940:KRAD RS11780
gene id: 266940:KRAD_RS11780
uniprot id: A6WGC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS08190
gene id: 266940:KRAD_RS08190
uniprot id: A6W5I7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

266940:KRAD RS22720
gene id: 266940:KRAD_RS22720
uniprot id: A6WA73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS11115
gene id: 266940:KRAD_RS11115
uniprot id: A6W3W8
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS07190
gene id: 266940:KRAD_RS07190
uniprot id: A6W632
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS18630
gene id: 266940:KRAD_RS18630
uniprot id: A6WCK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

266940:KRAD RS09845
gene id: 266940:KRAD_RS09845
uniprot id: A6W4L6
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

266940:KRAD RS17145
gene id: 266940:KRAD_RS17145
uniprot id: A6WDE0
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

266940:KRAD RS20525
gene id: 266940:KRAD_RS20525
uniprot id: A6WBI7
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS22850
gene id: 266940:KRAD_RS22850
uniprot id: A6WGQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

266940:KRAD RS09655
gene id: 266940:KRAD_RS09655
uniprot id: A6W4Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS08030
gene id: 266940:KRAD_RS08030
uniprot id: A6W5M0
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

266940:KRAD RS09650
gene id: 266940:KRAD_RS09650
uniprot id: A6W4Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266940:KRAD RS12845
gene id: 266940:KRAD_RS12845
uniprot id: A6WFS2
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

266940:KRAD RS09825
gene id: 266940:KRAD_RS09825
uniprot id: A6W4M0
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS09630
gene id: 266940:KRAD_RS09630
uniprot id: A6W4Q7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

266940:KRAD RS10560
gene id: 266940:KRAD_RS10560
uniprot id: A6W477
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

266940:KRAD RS11515
gene id: 266940:KRAD_RS11515
uniprot id: A6WGG9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

266940:KRAD RS15700
gene id: 266940:KRAD_RS15700
uniprot id: A6WE71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

266940:KRAD RS22735
gene id: 266940:KRAD_RS22735
uniprot id: A6WA69
names: Similarity
messages: Belongs to the malate synthase family.

266940:KRAD RS04395
gene id: 266940:KRAD_RS04395
uniprot id: A6W7N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

266940:KRAD RS09425
gene id: 266940:KRAD_RS09425
uniprot id: A6W4U6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

266940:KRAD RS13965
gene id: 266940:KRAD_RS13965
uniprot id: A6WF57
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

266940:KRAD RS05850
gene id: 266940:KRAD_RS05850
uniprot id: A6W6V1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

266940:KRAD RS15965
gene id: 266940:KRAD_RS15965
uniprot id: A6WE18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

266940:KRAD RS03115
gene id: 266940:KRAD_RS03115
uniprot id: A6W8D4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

266940:KRAD RS13085
gene id: 266940:KRAD_RS13085
uniprot id: A6WFM4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

266940:KRAD RS04585
gene id: 266940:KRAD_RS04585
uniprot id: A6W7J8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

266940:KRAD RS19445
gene id: 266940:KRAD_RS19445
uniprot id: A6WC46
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

266940:KRAD RS19635
gene id: 266940:KRAD_RS19635
uniprot id: A6WC09
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

266940:KRAD RS06030
gene id: 266940:KRAD_RS06030
uniprot id: A6W6R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

266940:KRAD RS18005
gene id: 266940:KRAD_RS18005
uniprot id: A6WCX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

266940:KRAD RS06795
gene id: 266940:KRAD_RS06795
uniprot id: A6W6B4
names: Similarity
messages: Belongs to the catalase family.

266940:KRAD RS04600
gene id: 266940:KRAD_RS04600
uniprot id: A6W7J5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

266940:KRAD RS21360
gene id: 266940:KRAD_RS21360
uniprot id: A6WB20
names: Subcellular Location Annotation
messages: Membrane

266940:KRAD RS18840
gene id: 266940:KRAD_RS18840
uniprot id: A6WCG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

266940:KRAD RS08295
gene id: 266940:KRAD_RS08295
uniprot id: A6W5G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 26 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

266940:KRAD RS07675
gene id: 266940:KRAD_RS07675
uniprot id: A6W5T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

266940:KRAD RS19055
gene id: 266940:KRAD_RS19055
uniprot id: A6WCC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

266940:KRAD RS22555
gene id: 266940:KRAD_RS22555
uniprot id: A6WAA6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

266940:KRAD RS01010
gene id: 266940:KRAD_RS01010
uniprot id: A6W9K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

266940:KRAD RS27675
gene id: 266940:KRAD_RS27675
uniprot id: A6WCW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

266940:KRAD RS03635
gene id: 266940:KRAD_RS03635
uniprot id: A6W834
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

266940:KRAD RS13980
gene id: 266940:KRAD_RS13980
uniprot id: A6WF54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

266940:KRAD RS11255
gene id: 266940:KRAD_RS11255
uniprot id: A6WGM1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

266940:KRAD RS05540
gene id: 266940:KRAD_RS05540
uniprot id: A6W711
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

266940:KRAD RS16245
gene id: 266940:KRAD_RS16245
uniprot id: A6WDW4
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

266940:KRAD RS13495
gene id: 266940:KRAD_RS13495
uniprot id: A6WFE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

266940:KRAD RS13300
gene id: 266940:KRAD_RS13300
uniprot id: A6WFI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

266940:KRAD RS13050
gene id: 266940:KRAD_RS13050
uniprot id: A6WFN1
names: Similarity
messages: Belongs to the hyi family.

266940:KRAD RS05775
gene id: 266940:KRAD_RS05775
uniprot id: A6W6W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

266940:KRAD RS03920
gene id: 266940:KRAD_RS03920
uniprot id: A6W7X6
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266940:KRAD RS17825
gene id: 266940:KRAD_RS17825
uniprot id: A6WD09
names: Subcellular Location Annotation
messages: Cytoplasm

266940:KRAD RS13460
gene id: 266940:KRAD_RS13460
uniprot id: A6WFF1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

266940:KRAD RS10525
gene id: 266940:KRAD_RS10525
uniprot id: A6W484
names: Subcellular Location Annotation
messages: Membrane