2599595:HWQ56 RS25815
gene id: 2599595:HWQ56_RS25815
uniprot id: A0A7D5HRM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

2599595:HWQ56 RS02845
gene id: 2599595:HWQ56_RS02845
uniprot id: A0A7D5D4E0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

2599595:HWQ56 RS05965
gene id: 2599595:HWQ56_RS05965
uniprot id: A0A7D5D5L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

2599595:HWQ56 RS28025
gene id: 2599595:HWQ56_RS28025
uniprot id: A0A7D5H9D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2599595:HWQ56 RS05655
gene id: 2599595:HWQ56_RS05655
uniprot id: A0A7D5D571
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

2599595:HWQ56 RS01450
gene id: 2599595:HWQ56_RS01450
uniprot id: A0A7D5GYF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

2599595:HWQ56 RS19670
gene id: 2599595:HWQ56_RS19670
uniprot id: A0A7D5H8T1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2599595:HWQ56 RS21395
gene id: 2599595:HWQ56_RS21395
uniprot id: A0A7D5HZ65
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

2599595:HWQ56 RS22430
gene id: 2599595:HWQ56_RS22430
uniprot id: A0A7D5DBV5
names: Subcellular Location Annotation
messages: Cytoplasm

2599595:HWQ56 RS28315
gene id: 2599595:HWQ56_RS28315
uniprot id: A0A7D5DBM5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

2599595:HWQ56 RS20610
gene id: 2599595:HWQ56_RS20610
uniprot id: A0A7D5DAL4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

2599595:HWQ56 RS09635
gene id: 2599595:HWQ56_RS09635
uniprot id: A0A7D5HMU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2599595:HWQ56 RS25795
gene id: 2599595:HWQ56_RS25795
uniprot id: A0A7D5HA44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2599595:HWQ56 RS25850
gene id: 2599595:HWQ56_RS25850
uniprot id: A0A7D5DBV8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2599595:HWQ56 RS22085
gene id: 2599595:HWQ56_RS22085
uniprot id: A0A7D5D9K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

2599595:HWQ56 RS25875
gene id: 2599595:HWQ56_RS25875
uniprot id: A0A7D5DAG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2599595:HWQ56 RS02790
gene id: 2599595:HWQ56_RS02790
uniprot id: A0A7D5GYG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

2599595:HWQ56 RS21430
gene id: 2599595:HWQ56_RS21430
uniprot id: A0A7D5DAL4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

2599595:HWQ56 RS01925
gene id: 2599595:HWQ56_RS01925
uniprot id: A0A7D5D4F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

2599595:HWQ56 RS09770
gene id: 2599595:HWQ56_RS09770
uniprot id: A0A7D5DAL4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

2599595:HWQ56 RS25785
gene id: 2599595:HWQ56_RS25785
uniprot id: A0A7D5H6R5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2599595:HWQ56 RS01230
gene id: 2599595:HWQ56_RS01230
uniprot id: A0A7D5GYD8
names: Similarity
messages: Belongs to the P(II) protein family.

2599595:HWQ56 RS25805
gene id: 2599595:HWQ56_RS25805
uniprot id: A0A7D5HJP1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2599595:HWQ56 RS25865
gene id: 2599595:HWQ56_RS25865
uniprot id: A0A7D5DAX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2599595:HWQ56 RS25835
gene id: 2599595:HWQ56_RS25835
uniprot id: A0A7D5DB00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2599595:HWQ56 RS03735
gene id: 2599595:HWQ56_RS03735
uniprot id: A0A7D5D536
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2599595:HWQ56 RS02840
gene id: 2599595:HWQ56_RS02840
uniprot id: A0A7D5D4T7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

2599595:HWQ56 RS25650
gene id: 2599595:HWQ56_RS25650
uniprot id: A0A7D5DBU0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

2599595:HWQ56 RS25855
gene id: 2599595:HWQ56_RS25855
uniprot id: A0A7D5DB57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2599595:HWQ56 RS24865
gene id: 2599595:HWQ56_RS24865
uniprot id: A0A7D5D9Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

2599595:HWQ56 RS25820
gene id: 2599595:HWQ56_RS25820
uniprot id: A0A7D5H8R5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2599595:HWQ56 RS25845
gene id: 2599595:HWQ56_RS25845
uniprot id: A0A7D5D9J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2599595:HWQ56 RS03665
gene id: 2599595:HWQ56_RS03665
uniprot id: A0A7D5DAL4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

2599595:HWQ56 RS21770
gene id: 2599595:HWQ56_RS21770
uniprot id: A0A7D5DBN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2599595:HWQ56 RS02285
gene id: 2599595:HWQ56_RS02285
uniprot id: A0A7D5HDD5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

2599595:HWQ56 RS02855
gene id: 2599595:HWQ56_RS02855
uniprot id: A0A7D5D4P3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

2599595:HWQ56 RS24330
gene id: 2599595:HWQ56_RS24330
uniprot id: A0A7D5D959
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

2599595:HWQ56 RS09525
gene id: 2599595:HWQ56_RS09525
uniprot id: A0A7D5GZT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2599595:HWQ56 RS21905
gene id: 2599595:HWQ56_RS21905
uniprot id: A0A7D5HIP8
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

2599595:HWQ56 RS27940
gene id: 2599595:HWQ56_RS27940
uniprot id: A0A7D5HSF3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2599595:HWQ56 RS28755
gene id: 2599595:HWQ56_RS28755
uniprot id: A0A7D5DB62
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2599595:HWQ56 RS23300
gene id: 2599595:HWQ56_RS23300
uniprot id: A0A7D5H2H7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2599595:HWQ56 RS19650
gene id: 2599595:HWQ56_RS19650
uniprot id: A0A7D5D8X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2599595:HWQ56 RS25910
gene id: 2599595:HWQ56_RS25910
uniprot id: A0A7D5H332
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2599595:HWQ56 RS25890
gene id: 2599595:HWQ56_RS25890
uniprot id: A0A7D5H8N3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2599595:HWQ56 RS20665
gene id: 2599595:HWQ56_RS20665
uniprot id: A0A7D5H5G4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2599595:HWQ56 RS24780
gene id: 2599595:HWQ56_RS24780
uniprot id: A0A7D5DAR1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2599595:HWQ56 RS01905
gene id: 2599595:HWQ56_RS01905
uniprot id: A0A7D5D4K7
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

2599595:HWQ56 RS25895
gene id: 2599595:HWQ56_RS25895
uniprot id: A0A7D5HA53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2599595:HWQ56 RS21370
gene id: 2599595:HWQ56_RS21370
uniprot id: A0A7D5HIK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2599595:HWQ56 RS24830
gene id: 2599595:HWQ56_RS24830
uniprot id: A0A7D5HJE8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2599595:HWQ56 RS25860
gene id: 2599595:HWQ56_RS25860
uniprot id: A0A7D5DAW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2599595:HWQ56 RS22235
gene id: 2599595:HWQ56_RS22235
uniprot id: A0A7D5HQS0
names: Subcellular Location Annotation
messages: Cytoplasm

2599595:HWQ56 RS22425
gene id: 2599595:HWQ56_RS22425
uniprot id: A0A7D5D9N1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2599595:HWQ56 RS25880
gene id: 2599595:HWQ56_RS25880
uniprot id: A0A7D5DCV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2599595:HWQ56 RS20685
gene id: 2599595:HWQ56_RS20685
uniprot id: A0A7D5HIF3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2599595:HWQ56 RS25810
gene id: 2599595:HWQ56_RS25810
uniprot id: A0A7D5H329
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

2599595:HWQ56 RS25915
gene id: 2599595:HWQ56_RS25915
uniprot id: A0A7D5HRN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2599595:HWQ56 RS28685
gene id: 2599595:HWQ56_RS28685
uniprot id: A0A7D5HSK9
names: Subcellular Location Annotation
messages: Membrane

2599595:HWQ56 RS21750
gene id: 2599595:HWQ56_RS21750
uniprot id: A0A7D5D9K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2599595:HWQ56 RS25870
gene id: 2599595:HWQ56_RS25870
uniprot id: A0A7D5D9Q3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2599595:HWQ56 RS28005
gene id: 2599595:HWQ56_RS28005
uniprot id: A0A7D5DA89
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

2599595:HWQ56 RS06630
gene id: 2599595:HWQ56_RS06630
uniprot id: A0A7D5H1Y6
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

2599595:HWQ56 RS03165
gene id: 2599595:HWQ56_RS03165
uniprot id: A0A7D5D5E3
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

2599595:HWQ56 RS28675
gene id: 2599595:HWQ56_RS28675
uniprot id: A0A7D5HKD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2599595:HWQ56 RS25765
gene id: 2599595:HWQ56_RS25765
uniprot id: A0A7D5DAW5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2599595:HWQ56 RS23960
gene id: 2599595:HWQ56_RS23960
uniprot id: A0A7D5HR88
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

2599595:HWQ56 RS25775
gene id: 2599595:HWQ56_RS25775
uniprot id: A0A7D5DAF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2599595:HWQ56 RS24835
gene id: 2599595:HWQ56_RS24835
uniprot id: A0A7D5H2U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2599595:HWQ56 RS27945
gene id: 2599595:HWQ56_RS27945
uniprot id: A0A7D5H9A2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2599595:HWQ56 RS17555
gene id: 2599595:HWQ56_RS17555
uniprot id: A0A7D5H6X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

2599595:HWQ56 RS19665
gene id: 2599595:HWQ56_RS19665
uniprot id: A0A7D5H7B5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2599595:HWQ56 RS06550
gene id: 2599595:HWQ56_RS06550
uniprot id: A0A7D5GZB5
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

2599595:HWQ56 RS25900
gene id: 2599595:HWQ56_RS25900
uniprot id: A0A7D5H3U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2599595:HWQ56 RS24805
gene id: 2599595:HWQ56_RS24805
uniprot id: A0A7D5DCI3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

2599595:HWQ56 RS22130
gene id: 2599595:HWQ56_RS22130
uniprot id: A0A7D5HQR6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2599595:HWQ56 RS05175
gene id: 2599595:HWQ56_RS05175
uniprot id: A0A7D5H3U2
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

2599595:HWQ56 RS20670
gene id: 2599595:HWQ56_RS20670
uniprot id: A0A7D5H7K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

2599595:HWQ56 RS05955
gene id: 2599595:HWQ56_RS05955
uniprot id: A0A7D5D506
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

2599595:HWQ56 RS09545
gene id: 2599595:HWQ56_RS09545
uniprot id: A0A7D5HVZ5
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

2599595:HWQ56 RS25840
gene id: 2599595:HWQ56_RS25840
uniprot id: A0A7D5DA78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2599595:HWQ56 RS20215
gene id: 2599595:HWQ56_RS20215
uniprot id: A0A7D5HIC3
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

2599595:HWQ56 RS03855
gene id: 2599595:HWQ56_RS03855
uniprot id: A0A7D5D4L4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

2599595:HWQ56 RS05225
gene id: 2599595:HWQ56_RS05225
uniprot id: A0A7D5D4Z8
names: Subcellular Location Annotation
messages: Cytoplasm

2599595:HWQ56 RS25425
gene id: 2599595:HWQ56_RS25425
uniprot id: A0A7D5D9F2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

2599595:HWQ56 RS12295
gene id: 2599595:HWQ56_RS12295
uniprot id: A0A7D5DAL4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

2599595:HWQ56 RS21765
gene id: 2599595:HWQ56_RS21765
uniprot id: A0A7D5D9I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2599595:HWQ56 RS04510
gene id: 2599595:HWQ56_RS04510
uniprot id: A0A7D5GYX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

2599595:HWQ56 RS26380
gene id: 2599595:HWQ56_RS26380
uniprot id: A0A7D5DE80
names: Function
names: Similarity
messages: Belongs to the PqqA family.
messages: Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.

2599595:HWQ56 RS21015
gene id: 2599595:HWQ56_RS21015
uniprot id: A0A7D5D9C3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2599595:HWQ56 RS20740
gene id: 2599595:HWQ56_RS20740
uniprot id: A0A7D5DAM1
names: Similarity
messages: Belongs to the UPF0434 family.

2599595:HWQ56 RS27575
gene id: 2599595:HWQ56_RS27575
uniprot id: A0A7D5DAV1
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

2599595:HWQ56 RS07280
gene id: 2599595:HWQ56_RS07280
uniprot id: A0A7D5D5A8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2599595:HWQ56 RS06555
gene id: 2599595:HWQ56_RS06555
uniprot id: A0A7D5HM34
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2599595:HWQ56 RS09560
gene id: 2599595:HWQ56_RS09560
uniprot id: A0A7D5D5V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2599595:HWQ56 RS10040
gene id: 2599595:HWQ56_RS10040
uniprot id: A0A7D5H682
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

2599595:HWQ56 RS27165
gene id: 2599595:HWQ56_RS27165
uniprot id: A0A7D5H718
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

2599595:HWQ56 RS00070
gene id: 2599595:HWQ56_RS00070
uniprot id: A0A7D5D4A6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2599595:HWQ56 RS25800
gene id: 2599595:HWQ56_RS25800
uniprot id: A0A7D5H3T7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2599595:HWQ56 RS00565
gene id: 2599595:HWQ56_RS00565
uniprot id: A0A7D5H2T4
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

2599595:HWQ56 RS28035
gene id: 2599595:HWQ56_RS28035
uniprot id: A0A7D5H4G1
names: Similarity
messages: Belongs to the RutC family.

2599595:HWQ56 RS19690
gene id: 2599595:HWQ56_RS19690
uniprot id: A0A7D5H1P0
names: Subcellular Location Annotation
messages: Cytoplasm

2599595:HWQ56 RS26250
gene id: 2599595:HWQ56_RS26250
uniprot id: A0A7D5HJS7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2599595:HWQ56 RS05970
gene id: 2599595:HWQ56_RS05970
uniprot id: A0A7D5D581
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2599595:HWQ56 RS03850
gene id: 2599595:HWQ56_RS03850
uniprot id: A0A7D5D542
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

2599595:HWQ56 RS22980
gene id: 2599595:HWQ56_RS22980
uniprot id: A0A7D5H2U8
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.