2585117:Alistipes RS05165
gene id: 2585117:Alistipes_RS05165
uniprot id: A0A4Y1WLB0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

2585117:Alistipes RS02005
gene id: 2585117:Alistipes_RS02005
uniprot id: A0A4Y1WHZ3
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

2585117:Alistipes RS13875
gene id: 2585117:Alistipes_RS13875
uniprot id: A0A4Y1WPP3
names: Function
messages: Might have a role analogous to that of eukaryotic histone proteins.

2585117:Alistipes RS09030
gene id: 2585117:Alistipes_RS09030
uniprot id: A0A4Y1WMS1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

2585117:Alistipes RS01475
gene id: 2585117:Alistipes_RS01475
uniprot id: A0A4Y1WH35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2585117:Alistipes RS01730
gene id: 2585117:Alistipes_RS01730
uniprot id: A0A4Y1WHC7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2585117:Alistipes RS01920
gene id: 2585117:Alistipes_RS01920
uniprot id: A0A4Y1WJ64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

2585117:Alistipes RS04945
gene id: 2585117:Alistipes_RS04945
uniprot id: A0A4Y1WJK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2585117:Alistipes RS03770
gene id: 2585117:Alistipes_RS03770
uniprot id: A0A4Y1X592
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

2585117:Alistipes RS08390
gene id: 2585117:Alistipes_RS08390
uniprot id: A0A4Y1X8N3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

2585117:Alistipes RS04340
gene id: 2585117:Alistipes_RS04340
uniprot id: A0A4Y1WKX0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2585117:Alistipes RS09110
gene id: 2585117:Alistipes_RS09110
uniprot id: A0A4Y1WM29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2585117:Alistipes RS09710
gene id: 2585117:Alistipes_RS09710
uniprot id: A0A4Y1WKI0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

2585117:Alistipes RS03595
gene id: 2585117:Alistipes_RS03595
uniprot id: A0A4Y1WH29
names: Similarity
messages: Belongs to the CinA family.

2585117:Alistipes RS11535
gene id: 2585117:Alistipes_RS11535
uniprot id: A0A4Y1WLL3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

2585117:Alistipes RS02430
gene id: 2585117:Alistipes_RS02430
uniprot id: A0A4Y1X612
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

2585117:Alistipes RS06860
gene id: 2585117:Alistipes_RS06860
uniprot id: A0A4Y1WM60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

2585117:Alistipes RS11420
gene id: 2585117:Alistipes_RS11420
uniprot id: A0A4Y1WMM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2585117:Alistipes RS14415
gene id: 2585117:Alistipes_RS14415
uniprot id: A0A4Y1WNU0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2585117:Alistipes RS09895
gene id: 2585117:Alistipes_RS09895
uniprot id: A0A4Y1WNI2
names: Subcellular Location Annotation
messages: Membrane

2585117:Alistipes RS01605
gene id: 2585117:Alistipes_RS01605
uniprot id: A0A4Y1WG21
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2585117:Alistipes RS04900
gene id: 2585117:Alistipes_RS04900
uniprot id: A0A4Y1X832
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2585117:Alistipes RS02745
gene id: 2585117:Alistipes_RS02745
uniprot id: A0A4Y1WK36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2585117:Alistipes RS01425
gene id: 2585117:Alistipes_RS01425
uniprot id: A0A4Y1X6T1
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

2585117:Alistipes RS03640
gene id: 2585117:Alistipes_RS03640
uniprot id: A0A4Y1WHX0
names: Similarity
messages: Belongs to the SusD family.

2585117:Alistipes RS04345
gene id: 2585117:Alistipes_RS04345
uniprot id: A0A4Y1WKB0
names: Subcellular Location Annotation
messages: Membrane

2585117:Alistipes RS09510
gene id: 2585117:Alistipes_RS09510
uniprot id: A0A4Y1WKE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2585117:Alistipes RS10350
gene id: 2585117:Alistipes_RS10350
uniprot id: A0A4Y1XAN5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

2585117:Alistipes RS07045
gene id: 2585117:Alistipes_RS07045
uniprot id: A0A4Y1WLV3
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

2585117:Alistipes RS01775
gene id: 2585117:Alistipes_RS01775
uniprot id: A0A4Y1WHD5
names: Similarity
messages: Belongs to the transglycosylase Slt family.

2585117:Alistipes RS06210
gene id: 2585117:Alistipes_RS06210
uniprot id: A0A4Y1X6E6
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

2585117:Alistipes RS04890
gene id: 2585117:Alistipes_RS04890
uniprot id: A0A4Y1X5W6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2585117:Alistipes RS08265
gene id: 2585117:Alistipes_RS08265
uniprot id: A0A4Y1WJN1
names: Similarity
messages: Belongs to the SusD family.

2585117:Alistipes RS12345
gene id: 2585117:Alistipes_RS12345
uniprot id: A0A4Y1WM38
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

2585117:Alistipes RS08190
gene id: 2585117:Alistipes_RS08190
uniprot id: A0A4Y1WMI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

2585117:Alistipes RS04965
gene id: 2585117:Alistipes_RS04965
uniprot id: A0A4Y1WL68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2585117:Alistipes RS10835
gene id: 2585117:Alistipes_RS10835
uniprot id: A0A4Y1WMB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

2585117:Alistipes RS12865
gene id: 2585117:Alistipes_RS12865
uniprot id: A0A4Y1XC64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2585117:Alistipes RS13790
gene id: 2585117:Alistipes_RS13790
uniprot id: A0A4Y1XBK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

2585117:Alistipes RS10465
gene id: 2585117:Alistipes_RS10465
uniprot id: A0A4Y1WL10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

2585117:Alistipes RS06930
gene id: 2585117:Alistipes_RS06930
uniprot id: A0A4Y1X6Q2
names: Subcellular Location Annotation
messages: Membrane

2585117:Alistipes RS05355
gene id: 2585117:Alistipes_RS05355
uniprot id: A0A4Y1WL08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

2585117:Alistipes RS00115
gene id: 2585117:Alistipes_RS00115
uniprot id: A0A4Y1WIM7
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

2585117:Alistipes RS02380
gene id: 2585117:Alistipes_RS02380
uniprot id: A0A4Y1X4Y0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

2585117:Alistipes RS00285
gene id: 2585117:Alistipes_RS00285
uniprot id: A0A4Y1WG14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

2585117:Alistipes RS14625
gene id: 2585117:Alistipes_RS14625
uniprot id: A0A4Y1XBB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

2585117:Alistipes RS13350
gene id: 2585117:Alistipes_RS13350
uniprot id: A0A4Y1WNW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

2585117:Alistipes RS11165
gene id: 2585117:Alistipes_RS11165
uniprot id: A0A4Y1X995
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

2585117:Alistipes RS09035
gene id: 2585117:Alistipes_RS09035
uniprot id: A0A4Y1X9T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

2585117:Alistipes RS03865
gene id: 2585117:Alistipes_RS03865
uniprot id: A0A4Y1X5K9
names: Similarity
messages: Belongs to the Skp family.

2585117:Alistipes RS06480
gene id: 2585117:Alistipes_RS06480
uniprot id: A0A4Y1X6I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

2585117:Alistipes RS12875
gene id: 2585117:Alistipes_RS12875
uniprot id: A0A4Y1WNE2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

2585117:Alistipes RS01300
gene id: 2585117:Alistipes_RS01300
uniprot id: A0A4Y1WFU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

2585117:Alistipes RS10115
gene id: 2585117:Alistipes_RS10115
uniprot id: A0A4Y1X9M5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

2585117:Alistipes RS12665
gene id: 2585117:Alistipes_RS12665
uniprot id: A0A4Y1XAA8
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

2585117:Alistipes RS12580
gene id: 2585117:Alistipes_RS12580
uniprot id: A0A4Y1WM93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

2585117:Alistipes RS09400
gene id: 2585117:Alistipes_RS09400
uniprot id: A0A4Y1WKD2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2585117:Alistipes RS12715
gene id: 2585117:Alistipes_RS12715
uniprot id: A0A4Y1WQF8
names: Subcellular Location Annotation
messages: Cytoplasm

2585117:Alistipes RS13895
gene id: 2585117:Alistipes_RS13895
uniprot id: A0A4Y1XBM8
names: Subcellular Location Annotation
messages: Membrane

2585117:Alistipes RS10425
gene id: 2585117:Alistipes_RS10425
uniprot id: A0A4Y1X8R6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2585117:Alistipes RS06470
gene id: 2585117:Alistipes_RS06470
uniprot id: A0A4Y1X7K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

2585117:Alistipes RS06880
gene id: 2585117:Alistipes_RS06880
uniprot id: A0A4Y1WJP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

2585117:Alistipes RS09015
gene id: 2585117:Alistipes_RS09015
uniprot id: A0A4Y1X8R0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

2585117:Alistipes RS09515
gene id: 2585117:Alistipes_RS09515
uniprot id: A0A4Y1X874
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2585117:Alistipes RS02310
gene id: 2585117:Alistipes_RS02310
uniprot id: A0A4Y1WHK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

2585117:Alistipes RS00040
gene id: 2585117:Alistipes_RS00040
uniprot id: A0A4Y1X4R0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

2585117:Alistipes RS00155
gene id: 2585117:Alistipes_RS00155
uniprot id: A0A4Y1X3Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

2585117:Alistipes RS03880
gene id: 2585117:Alistipes_RS03880
uniprot id: A0A4Y1X6Q1
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

2585117:Alistipes RS02030
gene id: 2585117:Alistipes_RS02030
uniprot id: A0A4Y1WJ06
names: Subcellular Location Annotation
messages: Membrane

2585117:Alistipes RS00355
gene id: 2585117:Alistipes_RS00355
uniprot id: A0A4Y1WGH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

2585117:Alistipes RS01975
gene id: 2585117:Alistipes_RS01975
uniprot id: A0A4Y1X4L9
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

2585117:Alistipes RS04225
gene id: 2585117:Alistipes_RS04225
uniprot id: A0A4Y1WIL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

2585117:Alistipes RS01785
gene id: 2585117:Alistipes_RS01785
uniprot id: A0A4Y1WIV3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

2585117:Alistipes RS14570
gene id: 2585117:Alistipes_RS14570
uniprot id: A0A4Y1WNX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

2585117:Alistipes RS00005
gene id: 2585117:Alistipes_RS00005
uniprot id: A0A4Y1X391
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

2585117:Alistipes RS01990
gene id: 2585117:Alistipes_RS01990
uniprot id: A0A4Y1X7A9
names: Similarity
messages: Belongs to the SAICAR synthetase family.

2585117:Alistipes RS06980
gene id: 2585117:Alistipes_RS06980
uniprot id: A0A4Y1X6R4
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

2585117:Alistipes RS10855
gene id: 2585117:Alistipes_RS10855
uniprot id: A0A4Y1WL90
names: Subcellular Location Annotation
messages: Membrane

2585117:Alistipes RS04885
gene id: 2585117:Alistipes_RS04885
uniprot id: A0A4Y1WIK4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2585117:Alistipes RS09500
gene id: 2585117:Alistipes_RS09500
uniprot id: A0A4Y1WKE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

2585117:Alistipes RS01910
gene id: 2585117:Alistipes_RS01910
uniprot id: A0A4Y1WHY2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

2585117:Alistipes RS02270
gene id: 2585117:Alistipes_RS02270
uniprot id: A0A4Y1WHN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

2585117:Alistipes RS09900
gene id: 2585117:Alistipes_RS09900
uniprot id: A0A4Y1WLR1
names: Subcellular Location Annotation
messages: Membrane

2585117:Alistipes RS10390
gene id: 2585117:Alistipes_RS10390
uniprot id: A0A4Y1WNU6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

2585117:Alistipes RS12825
gene id: 2585117:Alistipes_RS12825
uniprot id: A0A4Y1WND4
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

2585117:Alistipes RS07715
gene id: 2585117:Alistipes_RS07715
uniprot id: A0A4Y1X8N6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

2585117:Alistipes RS09275
gene id: 2585117:Alistipes_RS09275
uniprot id: A0A4Y1X937
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2585117:Alistipes RS11780
gene id: 2585117:Alistipes_RS11780
uniprot id: A0A4Y1WPM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

2585117:Alistipes RS14150
gene id: 2585117:Alistipes_RS14150
uniprot id: A0A4Y1XDS9
names: Similarity
messages: Belongs to the thioredoxin family.

2585117:Alistipes RS04970
gene id: 2585117:Alistipes_RS04970
uniprot id: A0A4Y1X5Y2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2585117:Alistipes RS14115
gene id: 2585117:Alistipes_RS14115
uniprot id: A0A4Y1WN37
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

2585117:Alistipes RS10150
gene id: 2585117:Alistipes_RS10150
uniprot id: A0A4Y1WP17
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

2585117:Alistipes RS04915
gene id: 2585117:Alistipes_RS04915
uniprot id: A0A4Y1WL60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

2585117:Alistipes RS07645
gene id: 2585117:Alistipes_RS07645
uniprot id: A0A4Y1WM17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

2585117:Alistipes RS04905
gene id: 2585117:Alistipes_RS04905
uniprot id: A0A4Y1WKR5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2585117:Alistipes RS11160
gene id: 2585117:Alistipes_RS11160
uniprot id: A0A4Y1WM30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

2585117:Alistipes RS05005
gene id: 2585117:Alistipes_RS05005
uniprot id: A0A4Y1WKT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2585117:Alistipes RS13330
gene id: 2585117:Alistipes_RS13330
uniprot id: A0A4Y1WMN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

2585117:Alistipes RS01705
gene id: 2585117:Alistipes_RS01705
uniprot id: A0A4Y1WG41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

2585117:Alistipes RS06465
gene id: 2585117:Alistipes_RS06465
uniprot id: A0A4Y1WLD9
names: Similarity
messages: Belongs to the asparaginase 1 family.

2585117:Alistipes RS01495
gene id: 2585117:Alistipes_RS01495
uniprot id: A0A4Y1WIP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

2585117:Alistipes RS04710
gene id: 2585117:Alistipes_RS04710
uniprot id: A0A4Y1WKH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2585117:Alistipes RS06985
gene id: 2585117:Alistipes_RS06985
uniprot id: A0A4Y1X9L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

2585117:Alistipes RS13355
gene id: 2585117:Alistipes_RS13355
uniprot id: A0A4Y1WQG7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

2585117:Alistipes RS02515
gene id: 2585117:Alistipes_RS02515
uniprot id: A0A4Y1WHN2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

2585117:Alistipes RS00295
gene id: 2585117:Alistipes_RS00295
uniprot id: A0A4Y1WH39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2585117:Alistipes RS13825
gene id: 2585117:Alistipes_RS13825
uniprot id: A0A4Y1XAJ9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

2585117:Alistipes RS09470
gene id: 2585117:Alistipes_RS09470
uniprot id: A0A4Y1WLK6
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

2585117:Alistipes RS08385
gene id: 2585117:Alistipes_RS08385
uniprot id: A0A4Y1X8U7
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

2585117:Alistipes RS00540
gene id: 2585117:Alistipes_RS00540
uniprot id: A0A4Y1WFG1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

2585117:Alistipes RS11340
gene id: 2585117:Alistipes_RS11340
uniprot id: A0A4Y1WP14
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2585117:Alistipes RS07050
gene id: 2585117:Alistipes_RS07050
uniprot id: A0A4Y1WK66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

2585117:Alistipes RS02570
gene id: 2585117:Alistipes_RS02570
uniprot id: A0A4Y1WJH4
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

2585117:Alistipes RS04155
gene id: 2585117:Alistipes_RS04155
uniprot id: A0A4Y1WK64
names: Similarity
messages: Belongs to the peptidase S8 family.

2585117:Alistipes RS05050
gene id: 2585117:Alistipes_RS05050
uniprot id: A0A4Y1WJ28
names: Similarity
messages: Belongs to the XseB family.

2585117:Alistipes RS09040
gene id: 2585117:Alistipes_RS09040
uniprot id: A0A4Y1X804
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

2585117:Alistipes RS06785
gene id: 2585117:Alistipes_RS06785
uniprot id: A0A4Y1WIT2
names: Subcellular Location Annotation
messages: Membrane

2585117:Alistipes RS02290
gene id: 2585117:Alistipes_RS02290
uniprot id: A0A4Y1X7K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

2585117:Alistipes RS01225
gene id: 2585117:Alistipes_RS01225
uniprot id: A0A4Y1X4W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

2585117:Alistipes RS06840
gene id: 2585117:Alistipes_RS06840
uniprot id: A0A4Y1WKM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

2585117:Alistipes RS10160
gene id: 2585117:Alistipes_RS10160
uniprot id: A0A4Y1WKT1
names: Subcellular Location Annotation
messages: Membrane

2585117:Alistipes RS14200
gene id: 2585117:Alistipes_RS14200
uniprot id: A0A4Y1WR70
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

2585117:Alistipes RS11980
gene id: 2585117:Alistipes_RS11980
uniprot id: A0A4Y1WQ24
names: Subcellular Location Annotation
messages: Membrane

2585117:Alistipes RS01205
gene id: 2585117:Alistipes_RS01205
uniprot id: A0A4Y1WGK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2585117:Alistipes RS01695
gene id: 2585117:Alistipes_RS01695
uniprot id: A0A4Y1WIT5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2585117:Alistipes RS03765
gene id: 2585117:Alistipes_RS03765
uniprot id: A0A4Y1WKL7
names: Similarity
messages: Belongs to the MreC family.

2585117:Alistipes RS12065
gene id: 2585117:Alistipes_RS12065
uniprot id: A0A4Y1WNQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

2585117:Alistipes RS11760
gene id: 2585117:Alistipes_RS11760
uniprot id: A0A4Y1WMF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

2585117:Alistipes RS04565
gene id: 2585117:Alistipes_RS04565
uniprot id: A0A4Y1WHL3
names: Similarity
messages: Belongs to the type IA topoisomerase family.

2585117:Alistipes RS06065
gene id: 2585117:Alistipes_RS06065
uniprot id: A0A4Y1WIF7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

2585117:Alistipes RS03945
gene id: 2585117:Alistipes_RS03945
uniprot id: A0A4Y1WHA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

2585117:Alistipes RS04950
gene id: 2585117:Alistipes_RS04950
uniprot id: A0A4Y1X842
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2585117:Alistipes RS08450
gene id: 2585117:Alistipes_RS08450
uniprot id: A0A4Y1WKZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

2585117:Alistipes RS12920
gene id: 2585117:Alistipes_RS12920
uniprot id: A0A4Y1WMC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2585117:Alistipes RS12415
gene id: 2585117:Alistipes_RS12415
uniprot id: A0A4Y1XBB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

2585117:Alistipes RS08305
gene id: 2585117:Alistipes_RS08305
uniprot id: A0A4Y1XAC8
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

2585117:Alistipes RS11115
gene id: 2585117:Alistipes_RS11115
uniprot id: A0A4Y1WM15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

2585117:Alistipes RS09045
gene id: 2585117:Alistipes_RS09045
uniprot id: A0A4Y1WKW6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2585117:Alistipes RS07750
gene id: 2585117:Alistipes_RS07750
uniprot id: A0A4Y1X8A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2585117:Alistipes RS14315
gene id: 2585117:Alistipes_RS14315
uniprot id: A0A4Y1WN77
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

2585117:Alistipes RS05000
gene id: 2585117:Alistipes_RS05000
uniprot id: A0A4Y1WJ17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

2585117:Alistipes RS04850
gene id: 2585117:Alistipes_RS04850
uniprot id: A0A4Y1X669
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2585117:Alistipes RS08345
gene id: 2585117:Alistipes_RS08345
uniprot id: A0A4Y1WML1
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

2585117:Alistipes RS00890
gene id: 2585117:Alistipes_RS00890
uniprot id: A0A4Y1WFM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

2585117:Alistipes RS04980
gene id: 2585117:Alistipes_RS04980
uniprot id: A0A4Y1WHT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2585117:Alistipes RS03615
gene id: 2585117:Alistipes_RS03615
uniprot id: A0A4Y1X6C0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2585117:Alistipes RS11095
gene id: 2585117:Alistipes_RS11095
uniprot id: A0A4Y1WPJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

2585117:Alistipes RS02725
gene id: 2585117:Alistipes_RS02725
uniprot id: A0A4Y1WHS4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2585117:Alistipes RS08820
gene id: 2585117:Alistipes_RS08820
uniprot id: A0A4Y1WNA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

2585117:Alistipes RS01895
gene id: 2585117:Alistipes_RS01895
uniprot id: A0A4Y1WG78
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

2585117:Alistipes RS04030
gene id: 2585117:Alistipes_RS04030
uniprot id: A0A4Y1WKB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

2585117:Alistipes RS06760
gene id: 2585117:Alistipes_RS06760
uniprot id: A0A4Y1WK20
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2585117:Alistipes RS12650
gene id: 2585117:Alistipes_RS12650
uniprot id: A0A4Y1WND7
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

2585117:Alistipes RS06190
gene id: 2585117:Alistipes_RS06190
uniprot id: A0A4Y1X8K7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2585117:Alistipes RS14355
gene id: 2585117:Alistipes_RS14355
uniprot id: A0A4Y1WRA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

2585117:Alistipes RS10940
gene id: 2585117:Alistipes_RS10940
uniprot id: A0A4Y1WPG9
names: Similarity
messages: Belongs to the peptidase S8 family.

2585117:Alistipes RS07830
gene id: 2585117:Alistipes_RS07830
uniprot id: A0A4Y1WMB1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2585117:Alistipes RS11345
gene id: 2585117:Alistipes_RS11345
uniprot id: A0A4Y1WLH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2585117:Alistipes RS00645
gene id: 2585117:Alistipes_RS00645
uniprot id: A0A4Y1X530
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

2585117:Alistipes RS11120
gene id: 2585117:Alistipes_RS11120
uniprot id: A0A4Y1WLC1
names: Similarity
messages: Belongs to the UPF0102 family.

2585117:Alistipes RS04895
gene id: 2585117:Alistipes_RS04895
uniprot id: A0A4Y1X8P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2585117:Alistipes RS02700
gene id: 2585117:Alistipes_RS02700
uniprot id: A0A4Y1WGK6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2585117:Alistipes RS05010
gene id: 2585117:Alistipes_RS05010
uniprot id: A0A4Y1WJ26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2585117:Alistipes RS13345
gene id: 2585117:Alistipes_RS13345
uniprot id: A0A4Y1XA99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

2585117:Alistipes RS09250
gene id: 2585117:Alistipes_RS09250
uniprot id: A0A4Y1X9Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2585117:Alistipes RS00375
gene id: 2585117:Alistipes_RS00375
uniprot id: A0A4Y1WI36
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

2585117:Alistipes RS09485
gene id: 2585117:Alistipes_RS09485
uniprot id: A0A4Y1WNP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2585117:Alistipes RS05090
gene id: 2585117:Alistipes_RS05090
uniprot id: A0A4Y1X8U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

2585117:Alistipes RS03885
gene id: 2585117:Alistipes_RS03885
uniprot id: A0A4Y1WI18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2585117:Alistipes RS06770
gene id: 2585117:Alistipes_RS06770
uniprot id: A0A4Y1WLJ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

2585117:Alistipes RS12060
gene id: 2585117:Alistipes_RS12060
uniprot id: A0A4Y1WLV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

2585117:Alistipes RS04185
gene id: 2585117:Alistipes_RS04185
uniprot id: A0A4Y1WIK2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

2585117:Alistipes RS12365
gene id: 2585117:Alistipes_RS12365
uniprot id: A0A4Y1WN73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

2585117:Alistipes RS12870
gene id: 2585117:Alistipes_RS12870
uniprot id: A0A4Y1WQ71
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2585117:Alistipes RS01390
gene id: 2585117:Alistipes_RS01390
uniprot id: A0A4Y1X6F0
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2585117:Alistipes RS02495
gene id: 2585117:Alistipes_RS02495
uniprot id: A0A4Y1WGI7
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

2585117:Alistipes RS01545
gene id: 2585117:Alistipes_RS01545
uniprot id: A0A4Y1WIQ2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

2585117:Alistipes RS09295
gene id: 2585117:Alistipes_RS09295
uniprot id: A0A4Y1WK96
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

2585117:Alistipes RS11540
gene id: 2585117:Alistipes_RS11540
uniprot id: A0A4Y1XBK8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

2585117:Alistipes RS02720
gene id: 2585117:Alistipes_RS02720
uniprot id: A0A4Y1WID2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

2585117:Alistipes RS12290
gene id: 2585117:Alistipes_RS12290
uniprot id: A0A4Y1WM28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

2585117:Alistipes RS07985
gene id: 2585117:Alistipes_RS07985
uniprot id: A0A4Y1WLA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

2585117:Alistipes RS12620
gene id: 2585117:Alistipes_RS12620
uniprot id: A0A4Y1WPR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

2585117:Alistipes RS01505
gene id: 2585117:Alistipes_RS01505
uniprot id: A0A4Y1X565
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

2585117:Alistipes RS01455
gene id: 2585117:Alistipes_RS01455
uniprot id: A0A4Y1WFY5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

2585117:Alistipes RS05240
gene id: 2585117:Alistipes_RS05240
uniprot id: A0A4Y1WHY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

2585117:Alistipes RS07085
gene id: 2585117:Alistipes_RS07085
uniprot id: A0A4Y1WK71
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2585117:Alistipes RS09255
gene id: 2585117:Alistipes_RS09255
uniprot id: A0A4Y1WKZ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

2585117:Alistipes RS14325
gene id: 2585117:Alistipes_RS14325
uniprot id: A0A4Y1WN69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

2585117:Alistipes RS14035
gene id: 2585117:Alistipes_RS14035
uniprot id: A0A4Y1WPR9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2585117:Alistipes RS01220
gene id: 2585117:Alistipes_RS01220
uniprot id: A0A4Y1WGZ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

2585117:Alistipes RS07865
gene id: 2585117:Alistipes_RS07865
uniprot id: A0A4Y1WJF4
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

2585117:Alistipes RS07255
gene id: 2585117:Alistipes_RS07255
uniprot id: A0A4Y1WJ37
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2585117:Alistipes RS12555
gene id: 2585117:Alistipes_RS12555
uniprot id: A0A4Y1WQ21
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2585117:Alistipes RS02710
gene id: 2585117:Alistipes_RS02710
uniprot id: A0A4Y1X7T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2585117:Alistipes RS12225
gene id: 2585117:Alistipes_RS12225
uniprot id: A0A4Y1XAX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2585117:Alistipes RS03610
gene id: 2585117:Alistipes_RS03610
uniprot id: A0A4Y1X5F1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2585117:Alistipes RS11570
gene id: 2585117:Alistipes_RS11570
uniprot id: A0A4Y1WMQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

2585117:Alistipes RS11440
gene id: 2585117:Alistipes_RS11440
uniprot id: A0A4Y1WP34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2585117:Alistipes RS08320
gene id: 2585117:Alistipes_RS08320
uniprot id: A0A4Y1WJP8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

2585117:Alistipes RS15360
gene id: 2585117:Alistipes_RS15360
uniprot id: A0A4Y1XD91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

2585117:Alistipes RS00740
gene id: 2585117:Alistipes_RS00740
uniprot id: A0A4Y1X548
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

2585117:Alistipes RS08260
gene id: 2585117:Alistipes_RS08260
uniprot id: A0A4Y1WMC5
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

2585117:Alistipes RS12640
gene id: 2585117:Alistipes_RS12640
uniprot id: A0A4Y1WM75
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

2585117:Alistipes RS06710
gene id: 2585117:Alistipes_RS06710
uniprot id: A0A4Y1X6R5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

2585117:Alistipes RS05150
gene id: 2585117:Alistipes_RS05150
uniprot id: A0A4Y1WJ43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

2585117:Alistipes RS01680
gene id: 2585117:Alistipes_RS01680
uniprot id: A0A4Y1WJ21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

2585117:Alistipes RS14540
gene id: 2585117:Alistipes_RS14540
uniprot id: A0A4Y1WR42
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

2585117:Alistipes RS00535
gene id: 2585117:Alistipes_RS00535
uniprot id: A0A4Y1WFG2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

2585117:Alistipes RS09890
gene id: 2585117:Alistipes_RS09890
uniprot id: A0A4Y1WLT1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2585117:Alistipes RS05185
gene id: 2585117:Alistipes_RS05185
uniprot id: A0A4Y1WIR8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

2585117:Alistipes RS08315
gene id: 2585117:Alistipes_RS08315
uniprot id: A0A4Y1WJP2
names: Similarity
messages: Belongs to the RutC family.

2585117:Alistipes RS00595
gene id: 2585117:Alistipes_RS00595
uniprot id: A0A4Y1WFH0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

2585117:Alistipes RS13395
gene id: 2585117:Alistipes_RS13395
uniprot id: A0A4Y1WPG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

2585117:Alistipes RS07280
gene id: 2585117:Alistipes_RS07280
uniprot id: A0A4Y1WKA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

2585117:Alistipes RS14020
gene id: 2585117:Alistipes_RS14020
uniprot id: A0A4Y1WN11
names: Similarity
messages: Belongs to the SusD family.

2585117:Alistipes RS09055
gene id: 2585117:Alistipes_RS09055
uniprot id: A0A4Y1X7V2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

2585117:Alistipes RS10590
gene id: 2585117:Alistipes_RS10590
uniprot id: A0A4Y1WNY3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2585117:Alistipes RS06525
gene id: 2585117:Alistipes_RS06525
uniprot id: A0A4Y1X7U4
names: Similarity
messages: Belongs to the RecJ family.

2585117:Alistipes RS02730
gene id: 2585117:Alistipes_RS02730
uniprot id: A0A4Y1WJK4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

2585117:Alistipes RS07235
gene id: 2585117:Alistipes_RS07235
uniprot id: A0A4Y1WLZ3
names: Subcellular Location Annotation
messages: Membrane

2585117:Alistipes RS13955
gene id: 2585117:Alistipes_RS13955
uniprot id: A0A4Y1WN13
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2585117:Alistipes RS11200
gene id: 2585117:Alistipes_RS11200
uniprot id: A0A4Y1X9C1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

2585117:Alistipes RS11135
gene id: 2585117:Alistipes_RS11135
uniprot id: A0A4Y1WP91
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2585117:Alistipes RS01415
gene id: 2585117:Alistipes_RS01415
uniprot id: A0A4Y1WFW7
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

2585117:Alistipes RS10095
gene id: 2585117:Alistipes_RS10095
uniprot id: A0A4Y1X8P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

2585117:Alistipes RS04880
gene id: 2585117:Alistipes_RS04880
uniprot id: A0A4Y1X712
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2585117:Alistipes RS07380
gene id: 2585117:Alistipes_RS07380
uniprot id: A0A4Y1WKC9
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

2585117:Alistipes RS04955
gene id: 2585117:Alistipes_RS04955
uniprot id: A0A4Y1WKS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2585117:Alistipes RS11365
gene id: 2585117:Alistipes_RS11365
uniprot id: A0A4Y1X9P6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2585117:Alistipes RS14180
gene id: 2585117:Alistipes_RS14180
uniprot id: A0A4Y1WPU5
names: Subcellular Location Annotation
messages: Nucleus

2585117:Alistipes RS04845
gene id: 2585117:Alistipes_RS04845
uniprot id: A0A4Y1WIY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

2585117:Alistipes RS01555
gene id: 2585117:Alistipes_RS01555
uniprot id: A0A4Y1WG05
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

2585117:Alistipes RS09880
gene id: 2585117:Alistipes_RS09880
uniprot id: A0A4Y1WKL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

2585117:Alistipes RS06355
gene id: 2585117:Alistipes_RS06355
uniprot id: A0A4Y1X6H4
names: Similarity
messages: Belongs to the SusD family.

2585117:Alistipes RS06835
gene id: 2585117:Alistipes_RS06835
uniprot id: A0A4Y1WIT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

2585117:Alistipes RS03670
gene id: 2585117:Alistipes_RS03670
uniprot id: A0A4Y1WKK4
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

2585117:Alistipes RS09340
gene id: 2585117:Alistipes_RS09340
uniprot id: A0A4Y1WMZ3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

2585117:Alistipes RS08280
gene id: 2585117:Alistipes_RS08280
uniprot id: A0A4Y1WJN7
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

2585117:Alistipes RS11435
gene id: 2585117:Alistipes_RS11435
uniprot id: A0A4Y1X9K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2585117:Alistipes RS08180
gene id: 2585117:Alistipes_RS08180
uniprot id: A0A4Y1WLF0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

2585117:Alistipes RS04860
gene id: 2585117:Alistipes_RS04860
uniprot id: A0A4Y1WL50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

2585117:Alistipes RS13915
gene id: 2585117:Alistipes_RS13915
uniprot id: A0A4Y1XAT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

2585117:Alistipes RS04870
gene id: 2585117:Alistipes_RS04870
uniprot id: A0A4Y1WHS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2585117:Alistipes RS02470
gene id: 2585117:Alistipes_RS02470
uniprot id: A0A4Y1X594
names: Subcellular Location Annotation
messages: Membrane

2585117:Alistipes RS01345
gene id: 2585117:Alistipes_RS01345
uniprot id: A0A4Y1WIL6
names: Similarity
messages: Belongs to the SufE family.

2585117:Alistipes RS01530
gene id: 2585117:Alistipes_RS01530
uniprot id: A0A4Y1WIZ2
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

2585117:Alistipes RS04855
gene id: 2585117:Alistipes_RS04855
uniprot id: A0A4Y1WIZ8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2585117:Alistipes RS02150
gene id: 2585117:Alistipes_RS02150
uniprot id: A0A4Y1WGB1
names: Similarity
messages: Belongs to the SusD family.

2585117:Alistipes RS14275
gene id: 2585117:Alistipes_RS14275
uniprot id: A0A4Y1WN61
names: Similarity
messages: Belongs to the Rho family.

2585117:Alistipes RS00120
gene id: 2585117:Alistipes_RS00120
uniprot id: A0A4Y1WHZ2
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

2585117:Alistipes RS09315
gene id: 2585117:Alistipes_RS09315
uniprot id: A0A4Y1WM69
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2585117:Alistipes RS12880
gene id: 2585117:Alistipes_RS12880
uniprot id: A0A4Y1XBI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

2585117:Alistipes RS12410
gene id: 2585117:Alistipes_RS12410
uniprot id: A0A4Y1X9X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

2585117:Alistipes RS09385
gene id: 2585117:Alistipes_RS09385
uniprot id: A0A4Y1WNL8
names: Similarity
messages: Belongs to the SusD family.

2585117:Alistipes RS02080
gene id: 2585117:Alistipes_RS02080
uniprot id: A0A4Y1WJ18
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2585117:Alistipes RS06165
gene id: 2585117:Alistipes_RS06165
uniprot id: A0A4Y1WL89
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

2585117:Alistipes RS06505
gene id: 2585117:Alistipes_RS06505
uniprot id: A0A4Y1WJX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

2585117:Alistipes RS13795
gene id: 2585117:Alistipes_RS13795
uniprot id: A0A4Y1WQC9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

2585117:Alistipes RS04975
gene id: 2585117:Alistipes_RS04975
uniprot id: A0A4Y1X777
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2585117:Alistipes RS06900
gene id: 2585117:Alistipes_RS06900
uniprot id: A0A4Y1X6U7
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

2585117:Alistipes RS04995
gene id: 2585117:Alistipes_RS04995
uniprot id: A0A4Y1WJL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2585117:Alistipes RS02715
gene id: 2585117:Alistipes_RS02715
uniprot id: A0A4Y1X520
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

2585117:Alistipes RS05110
gene id: 2585117:Alistipes_RS05110
uniprot id: A0A4Y1WJ46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

2585117:Alistipes RS12095
gene id: 2585117:Alistipes_RS12095
uniprot id: A0A4Y1WLZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

2585117:Alistipes RS05155
gene id: 2585117:Alistipes_RS05155
uniprot id: A0A4Y1WKW7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2585117:Alistipes RS01380
gene id: 2585117:Alistipes_RS01380
uniprot id: A0A4Y1X471
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

2585117:Alistipes RS08535
gene id: 2585117:Alistipes_RS08535
uniprot id: A0A4Y1WKK8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2585117:Alistipes RS04940
gene id: 2585117:Alistipes_RS04940
uniprot id: A0A4Y1X5X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2585117:Alistipes RS11495
gene id: 2585117:Alistipes_RS11495
uniprot id: A0A4Y1WLK4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2585117:Alistipes RS11795
gene id: 2585117:Alistipes_RS11795
uniprot id: A0A4Y1WPA0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2585117:Alistipes RS08825
gene id: 2585117:Alistipes_RS08825
uniprot id: A0A4Y1WMN0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2585117:Alistipes RS07400
gene id: 2585117:Alistipes_RS07400
uniprot id: A0A4Y1X949
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

2585117:Alistipes RS11775
gene id: 2585117:Alistipes_RS11775
uniprot id: A0A4Y1XAV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

2585117:Alistipes RS04925
gene id: 2585117:Alistipes_RS04925
uniprot id: A0A4Y1X769
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2585117:Alistipes RS06830
gene id: 2585117:Alistipes_RS06830
uniprot id: A0A4Y1WJN3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.