2546350:E1B03 RS22015
gene id: 2546350:E1B03_RS22015
uniprot id: A0A4P6WSM4
names: Similarity
messages: Belongs to the UPF0235 family.

2546350:E1B03 RS03555
gene id: 2546350:E1B03_RS03555
uniprot id: A0A4P6WLK9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

2546350:E1B03 RS11910
gene id: 2546350:E1B03_RS11910
uniprot id: A0A4P6WJL8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2546350:E1B03 RS00335
gene id: 2546350:E1B03_RS00335
uniprot id: A0A4P6WFY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS25890
gene id: 2546350:E1B03_RS25890
uniprot id: A0A4P6WX10
names: Subcellular Location Annotation
messages: Cytoplasm

2546350:E1B03 RS23435
gene id: 2546350:E1B03_RS23435
uniprot id: A0A4P6WSL1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2546350:E1B03 RS23060
gene id: 2546350:E1B03_RS23060
uniprot id: A0A4P6WNL0
names: Similarity
names: Subunit
messages: Belongs to the RutC family.
messages: Homotrimer.

2546350:E1B03 RS03275
gene id: 2546350:E1B03_RS03275
uniprot id: A0A4P6WI08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2546350:E1B03 RS08700
gene id: 2546350:E1B03_RS08700
uniprot id: A0A4V1A9Y9
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

2546350:E1B03 RS25665
gene id: 2546350:E1B03_RS25665
uniprot id: A0A4V1AAV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

2546350:E1B03 RS19655
gene id: 2546350:E1B03_RS19655
uniprot id: A0A4P6WRP7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS21005
gene id: 2546350:E1B03_RS21005
uniprot id: A0A4P6WRE5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the UbiD family. YclC subfamily.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives.

2546350:E1B03 RS19890
gene id: 2546350:E1B03_RS19890
uniprot id: A0A4P6WNL4
names: Function
messages: Acts as a radical domain for damaged PFL and possibly other radical proteins.

2546350:E1B03 RS24130
gene id: 2546350:E1B03_RS24130
uniprot id: A0A4P6WW13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2546350:E1B03 RS23030
gene id: 2546350:E1B03_RS23030
uniprot id: A0A4P6WPI5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2546350:E1B03 RS04470
gene id: 2546350:E1B03_RS04470
uniprot id: A0A4P6WJC7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

2546350:E1B03 RS01080
gene id: 2546350:E1B03_RS01080
uniprot id: A0A4P6WGD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

2546350:E1B03 RS17990
gene id: 2546350:E1B03_RS17990
uniprot id: A0A4P6WSZ2
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.
messages: Membrane

2546350:E1B03 RS11820
gene id: 2546350:E1B03_RS11820
uniprot id: A0A4P6WM14
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

2546350:E1B03 RS09930
gene id: 2546350:E1B03_RS09930
uniprot id: A0A4P6WKR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HspQ family.
messages: Cytoplasm
messages: Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.

2546350:E1B03 RS25700
gene id: 2546350:E1B03_RS25700
uniprot id: A0A4P6WR40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2546350:E1B03 RS03865
gene id: 2546350:E1B03_RS03865
uniprot id: A0A4P6WI95
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

2546350:E1B03 RS06915
gene id: 2546350:E1B03_RS06915
uniprot id: A0A4P6WHH8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

2546350:E1B03 RS10205
gene id: 2546350:E1B03_RS10205
uniprot id: A0A4P6WKV2
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.

2546350:E1B03 RS08415
gene id: 2546350:E1B03_RS08415
uniprot id: A0A4P6WK21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

2546350:E1B03 RS01485
gene id: 2546350:E1B03_RS01485
uniprot id: A0A4P6WE20
names: Similarity
messages: Belongs to the Rht family.

2546350:E1B03 RS24215
gene id: 2546350:E1B03_RS24215
uniprot id: A0A4P6WW56
names: Similarity
messages: Belongs to the SlyX family.

2546350:E1B03 RS02330
gene id: 2546350:E1B03_RS02330
uniprot id: A0A4P6WF78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NusG family.
messages: Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.
messages: Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.

2546350:E1B03 RS24220
gene id: 2546350:E1B03_RS24220
uniprot id: A0A4P6WP41
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2546350:E1B03 RS21650
gene id: 2546350:E1B03_RS21650
uniprot id: A0A4P6WRQ2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2546350:E1B03 RS24825
gene id: 2546350:E1B03_RS24825
uniprot id: A0A4P6WTZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcrB family.
messages: Cell membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. Essential for lipoprotein maturation under conditions where membrane fluidity may be altered.

2546350:E1B03 RS25885
gene id: 2546350:E1B03_RS25885
uniprot id: A0A4V1AAV6
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS01020
gene id: 2546350:E1B03_RS01020
uniprot id: A0A4P6WJ60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.

2546350:E1B03 RS06745
gene id: 2546350:E1B03_RS06745
uniprot id: A0A4P6WKM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

2546350:E1B03 RS24020
gene id: 2546350:E1B03_RS24020
uniprot id: A0A4P6WNZ8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2546350:E1B03 RS06920
gene id: 2546350:E1B03_RS06920
uniprot id: A0A4P6WKI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2546350:E1B03 RS14070
gene id: 2546350:E1B03_RS14070
uniprot id: A0A4P6WNZ0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

2546350:E1B03 RS09500
gene id: 2546350:E1B03_RS09500
uniprot id: A0A4V1AA04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

2546350:E1B03 RS03405
gene id: 2546350:E1B03_RS03405
uniprot id: A0A4P6WEW9
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

2546350:E1B03 RS07165
gene id: 2546350:E1B03_RS07165
uniprot id: A0A4P6WMP3
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

2546350:E1B03 RS19235
gene id: 2546350:E1B03_RS19235
uniprot id: A0A4V1AAI3
names: Similarity
messages: Belongs to the CcmL/EutN family.

2546350:E1B03 RS15725
gene id: 2546350:E1B03_RS15725
uniprot id: A0A4P6WPQ6
names: Similarity
messages: Belongs to the RutC family.

2546350:E1B03 RS02045
gene id: 2546350:E1B03_RS02045
uniprot id: A0A4P6WIQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

2546350:E1B03 RS21165
gene id: 2546350:E1B03_RS21165
uniprot id: A0A4P6WP34
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2546350:E1B03 RS19325
gene id: 2546350:E1B03_RS19325
uniprot id: A0A4P6WQN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0370 family.
messages: Cell membrane

2546350:E1B03 RS03845
gene id: 2546350:E1B03_RS03845
uniprot id: A0A4P6WJH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

2546350:E1B03 RS18075
gene id: 2546350:E1B03_RS18075
uniprot id: A0A4P6WMQ1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RcsB family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
messages: Interacts with RcsD.
messages: Phosphorylated and activated by RcsD.

2546350:E1B03 RS16410
gene id: 2546350:E1B03_RS16410
uniprot id: A0A4P6WLK1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

2546350:E1B03 RS19240
gene id: 2546350:E1B03_RS19240
uniprot id: A0A4P6WTK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the bacterial microcompartments protein family.
messages: The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.

2546350:E1B03 RS08825
gene id: 2546350:E1B03_RS08825
uniprot id: A0A4P6WIA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

2546350:E1B03 RS26005
gene id: 2546350:E1B03_RS26005
uniprot id: A0A4P6WR80
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS11915
gene id: 2546350:E1B03_RS11915
uniprot id: A0A4P6WMZ4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2546350:E1B03 RS01055
gene id: 2546350:E1B03_RS01055
uniprot id: A0A4P6WKE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

2546350:E1B03 RS25245
gene id: 2546350:E1B03_RS25245
uniprot id: A0A4P6WWP6
names: Subcellular Location Annotation
messages: Cytoplasm

2546350:E1B03 RS15995
gene id: 2546350:E1B03_RS15995
uniprot id: A0A4P6WLS7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

2546350:E1B03 RS09245
gene id: 2546350:E1B03_RS09245
uniprot id: A0A4V1A9Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS10505
gene id: 2546350:E1B03_RS10505
uniprot id: A0A4P6WJF5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2546350:E1B03 RS09155
gene id: 2546350:E1B03_RS09155
uniprot id: A0A4P6WLR2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS24160
gene id: 2546350:E1B03_RS24160
uniprot id: A0A4P6WQF0
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

2546350:E1B03 RS19060
gene id: 2546350:E1B03_RS19060
uniprot id: A0A4P6WRF1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

2546350:E1B03 RS06870
gene id: 2546350:E1B03_RS06870
uniprot id: A0A4P6WKI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

2546350:E1B03 RS12620
gene id: 2546350:E1B03_RS12620
uniprot id: A0A4P6WJY1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

2546350:E1B03 RS13160
gene id: 2546350:E1B03_RS13160
uniprot id: A0A4P6WMK7
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

2546350:E1B03 RS23975
gene id: 2546350:E1B03_RS23975
uniprot id: A0A4V1AAS0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

2546350:E1B03 RS01030
gene id: 2546350:E1B03_RS01030
uniprot id: A0A4P6WGC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS23885
gene id: 2546350:E1B03_RS23885
uniprot id: A0A4P6WNY3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2546350:E1B03 RS08335
gene id: 2546350:E1B03_RS08335
uniprot id: A0A4P6WID8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

2546350:E1B03 RS14290
gene id: 2546350:E1B03_RS14290
uniprot id: A0A4P6WJQ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: Homodimer.

2546350:E1B03 RS25630
gene id: 2546350:E1B03_RS25630
uniprot id: A0A4P6WUF1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2546350:E1B03 RS22645
gene id: 2546350:E1B03_RS22645
uniprot id: A0A4P6WVA3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

2546350:E1B03 RS23345
gene id: 2546350:E1B03_RS23345
uniprot id: A0A4P6WVL2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

2546350:E1B03 RS08710
gene id: 2546350:E1B03_RS08710
uniprot id: A0A4P6WLI8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

2546350:E1B03 RS25655
gene id: 2546350:E1B03_RS25655
uniprot id: A0A4P6WWU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

2546350:E1B03 RS04935
gene id: 2546350:E1B03_RS04935
uniprot id: A0A4P6WJK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

2546350:E1B03 RS05170
gene id: 2546350:E1B03_RS05170
uniprot id: A0A4P6WLG5
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

2546350:E1B03 RS22650
gene id: 2546350:E1B03_RS22650
uniprot id: A0A4P6WSW4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2546350:E1B03 RS19550
gene id: 2546350:E1B03_RS19550
uniprot id: A0A4P6WTQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

2546350:E1B03 RS18425
gene id: 2546350:E1B03_RS18425
uniprot id: A0A4P6WQY8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2546350:E1B03 RS25695
gene id: 2546350:E1B03_RS25695
uniprot id: A0A4P6WTL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

2546350:E1B03 RS24045
gene id: 2546350:E1B03_RS24045
uniprot id: A0A4P6WPY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2546350:E1B03 RS07395
gene id: 2546350:E1B03_RS07395
uniprot id: A0A4P6WJW4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

2546350:E1B03 RS21405
gene id: 2546350:E1B03_RS21405
uniprot id: A0A4P6WUM4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: Homohexamer.

2546350:E1B03 RS25510
gene id: 2546350:E1B03_RS25510
uniprot id: A0A4P6WTH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

2546350:E1B03 RS09870
gene id: 2546350:E1B03_RS09870
uniprot id: A0A4P6WP96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

2546350:E1B03 RS17860
gene id: 2546350:E1B03_RS17860
uniprot id: A0A4P6WT82
names: Similarity
messages: Belongs to the peptidase C40 family.

2546350:E1B03 RS14950
gene id: 2546350:E1B03_RS14950
uniprot id: A0A4V1AAA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

2546350:E1B03 RS01600
gene id: 2546350:E1B03_RS01600
uniprot id: A0A4P6WIH7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

2546350:E1B03 RS01290
gene id: 2546350:E1B03_RS01290
uniprot id: A0A4P6WDZ2
names: Similarity
messages: Belongs to the thioredoxin family.

2546350:E1B03 RS03690
gene id: 2546350:E1B03_RS03690
uniprot id: A0A4P6WKS9
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.

2546350:E1B03 RS18465
gene id: 2546350:E1B03_RS18465
uniprot id: A0A4P6WQ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2546350:E1B03 RS04385
gene id: 2546350:E1B03_RS04385
uniprot id: A0A4P6WFC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

2546350:E1B03 RS06740
gene id: 2546350:E1B03_RS06740
uniprot id: A0A4P6WMG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS17815
gene id: 2546350:E1B03_RS17815
uniprot id: A0A4P6WL90
names: Similarity
messages: Belongs to the elongation factor P family.

2546350:E1B03 RS10470
gene id: 2546350:E1B03_RS10470
uniprot id: A0A4V1AA22
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

2546350:E1B03 RS01665
gene id: 2546350:E1B03_RS01665
uniprot id: A0A4V1A9K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

2546350:E1B03 RS04985
gene id: 2546350:E1B03_RS04985
uniprot id: A0A4P6WJL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

2546350:E1B03 RS17795
gene id: 2546350:E1B03_RS17795
uniprot id: A0A4P6WQP0
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

2546350:E1B03 RS22595
gene id: 2546350:E1B03_RS22595
uniprot id: A0A4P6WV96
names: Similarity
messages: Belongs to the class-I fumarase family.

2546350:E1B03 RS03030
gene id: 2546350:E1B03_RS03030
uniprot id: A0A4P6WHX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2546350:E1B03 RS06785
gene id: 2546350:E1B03_RS06785
uniprot id: A0A4V1A9V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

2546350:E1B03 RS18535
gene id: 2546350:E1B03_RS18535
uniprot id: A0A4P6WR08
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS19990
gene id: 2546350:E1B03_RS19990
uniprot id: A0A4V1AAJ7
names: Subcellular Location Annotation
messages: Cytoplasm

2546350:E1B03 RS11855
gene id: 2546350:E1B03_RS11855
uniprot id: A0A4P6WLU1
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS23495
gene id: 2546350:E1B03_RS23495
uniprot id: A0A4P6WVT6
names: Similarity
names: Subunit
messages: Belongs to the SIS family. GutQ/KpsF subfamily.
messages: Homotetramer.

2546350:E1B03 RS21355
gene id: 2546350:E1B03_RS21355
uniprot id: A0A4P6WNR0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2546350:E1B03 RS16955
gene id: 2546350:E1B03_RS16955
uniprot id: A0A4P6WPI9
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

2546350:E1B03 RS01565
gene id: 2546350:E1B03_RS01565
uniprot id: A0A4P6WI04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

2546350:E1B03 RS20040
gene id: 2546350:E1B03_RS20040
uniprot id: A0A4V1AAJ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

2546350:E1B03 RS25290
gene id: 2546350:E1B03_RS25290
uniprot id: A0A4V1AAU5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

2546350:E1B03 RS22980
gene id: 2546350:E1B03_RS22980
uniprot id: A0A4P6WT69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS05370
gene id: 2546350:E1B03_RS05370
uniprot id: A0A4V1A9S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

2546350:E1B03 RS24595
gene id: 2546350:E1B03_RS24595
uniprot id: A0A4P6WPC0
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

2546350:E1B03 RS19600
gene id: 2546350:E1B03_RS19600
uniprot id: A0A4P6WTR8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 2 iron ions per dimer. The dimer may bind additional iron ions.
messages: Homodimer; may form tetramers and higher multimers.
messages: Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.

2546350:E1B03 RS03975
gene id: 2546350:E1B03_RS03975
uniprot id: A0A4P6WJ40
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

2546350:E1B03 RS04820
gene id: 2546350:E1B03_RS04820
uniprot id: A0A4P6WI25
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

2546350:E1B03 RS21840
gene id: 2546350:E1B03_RS21840
uniprot id: A0A4V1AAN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LysR transcriptional regulatory family.
messages: Controls the transcription of genes involved in arginine and lysine metabolism.
messages: Homodimer.

2546350:E1B03 RS18625
gene id: 2546350:E1B03_RS18625
uniprot id: A0A4P6WT98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS09475
gene id: 2546350:E1B03_RS09475
uniprot id: A0A4P6WLR0
names: Similarity
names: Subunit
messages: Belongs to the glutaredoxin family.
messages: Monomer.

2546350:E1B03 RS09125
gene id: 2546350:E1B03_RS09125
uniprot id: A0A4P6WKW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

2546350:E1B03 RS09950
gene id: 2546350:E1B03_RS09950
uniprot id: A0A4P6WJ77
names: Similarity
messages: Belongs to the acylphosphatase family.

2546350:E1B03 RS01780
gene id: 2546350:E1B03_RS01780
uniprot id: A0A4P6WIK5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

2546350:E1B03 RS04995
gene id: 2546350:E1B03_RS04995
uniprot id: A0A4P6WGI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

2546350:E1B03 RS26040
gene id: 2546350:E1B03_RS26040
uniprot id: A0A4P6WX36
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS20635
gene id: 2546350:E1B03_RS20635
uniprot id: A0A4P6WR94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

2546350:E1B03 RS03065
gene id: 2546350:E1B03_RS03065
uniprot id: A0A4P6WHA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdgT transporter family.
messages: Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
messages: Cell membrane

2546350:E1B03 RS17125
gene id: 2546350:E1B03_RS17125
uniprot id: A0A4P6WKW9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2546350:E1B03 RS19820
gene id: 2546350:E1B03_RS19820
uniprot id: A0A4P6WN32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

2546350:E1B03 RS14910
gene id: 2546350:E1B03_RS14910
uniprot id: A0A4P6WP92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

2546350:E1B03 RS18335
gene id: 2546350:E1B03_RS18335
uniprot id: A0A4P6WTG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2546350:E1B03 RS12965
gene id: 2546350:E1B03_RS12965
uniprot id: A0A4P6WQM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

2546350:E1B03 RS00370
gene id: 2546350:E1B03_RS00370
uniprot id: A0A4V1A9I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

2546350:E1B03 RS02295
gene id: 2546350:E1B03_RS02295
uniprot id: A0A4P6WFD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

2546350:E1B03 RS24640
gene id: 2546350:E1B03_RS24640
uniprot id: A0A4P6WQM4
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

2546350:E1B03 RS23720
gene id: 2546350:E1B03_RS23720
uniprot id: A0A4P6WVX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

2546350:E1B03 RS11345
gene id: 2546350:E1B03_RS11345
uniprot id: A0A4P6WMM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs.
messages: Cytoplasm
messages: Interacts with TusE.

2546350:E1B03 RS15940
gene id: 2546350:E1B03_RS15940
uniprot id: A0A4P6WLR7
names: Similarity
names: Subunit
messages: Belongs to the KHG/KDPG aldolase family.
messages: Homotrimer.

2546350:E1B03 RS07415
gene id: 2546350:E1B03_RS07415
uniprot id: A0A4V1A9W6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2546350:E1B03 RS09830
gene id: 2546350:E1B03_RS09830
uniprot id: A0A4P6WKP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapC family.
messages: Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
messages: Cytoplasm
messages: Interacts directly with FtsZ.

2546350:E1B03 RS16485
gene id: 2546350:E1B03_RS16485
uniprot id: A0A4P6WKL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

2546350:E1B03 RS19625
gene id: 2546350:E1B03_RS19625
uniprot id: A0A4P6WQT1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

2546350:E1B03 RS07225
gene id: 2546350:E1B03_RS07225
uniprot id: A0A4P6WJB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

2546350:E1B03 RS01095
gene id: 2546350:E1B03_RS01095
uniprot id: A0A4P6WGY5
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS13405
gene id: 2546350:E1B03_RS13405
uniprot id: A0A4V1AA75
names: Cofactor
names: Function
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

2546350:E1B03 RS05395
gene id: 2546350:E1B03_RS05395
uniprot id: A0A4P6WJT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

2546350:E1B03 RS05020
gene id: 2546350:E1B03_RS05020
uniprot id: A0A4P6WJX1
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

2546350:E1B03 RS03150
gene id: 2546350:E1B03_RS03150
uniprot id: A0A4P6WFL7
names: Subcellular Location Annotation
messages: Cytoplasm

2546350:E1B03 RS24090
gene id: 2546350:E1B03_RS24090
uniprot id: A0A4P6WSL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2546350:E1B03 RS16005
gene id: 2546350:E1B03_RS16005
uniprot id: A0A4P6WKE6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

2546350:E1B03 RS17965
gene id: 2546350:E1B03_RS17965
uniprot id: A0A4P6WQ11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

2546350:E1B03 RS02680
gene id: 2546350:E1B03_RS02680
uniprot id: A0A4P6WKA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

2546350:E1B03 RS08390
gene id: 2546350:E1B03_RS08390
uniprot id: A0A4P6WNV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2546350:E1B03 RS20480
gene id: 2546350:E1B03_RS20480
uniprot id: A0A4P6WU72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AlaE exporter family.
messages: Cell inner membrane
messages: Exports L-alanine.

2546350:E1B03 RS09645
gene id: 2546350:E1B03_RS09645
uniprot id: A0A4P6WL50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

2546350:E1B03 RS19195
gene id: 2546350:E1B03_RS19195
uniprot id: A0A4P6WRF6
names: Function
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.

2546350:E1B03 RS24175
gene id: 2546350:E1B03_RS24175
uniprot id: A0A4V1AAS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

2546350:E1B03 RS19345
gene id: 2546350:E1B03_RS19345
uniprot id: A0A4V1AAI5
names: Similarity
messages: Belongs to the SAICAR synthetase family.

2546350:E1B03 RS04535
gene id: 2546350:E1B03_RS04535
uniprot id: A0A4P6WTW0
names: Function
names: Similarity
messages: Belongs to the thr operon leader peptide family.
messages: This protein is involved in control of the biosynthesis of threonine.

2546350:E1B03 RS17735
gene id: 2546350:E1B03_RS17735
uniprot id: A0A4P6WPS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

2546350:E1B03 RS24185
gene id: 2546350:E1B03_RS24185
uniprot id: A0A4P6WTL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2546350:E1B03 RS16000
gene id: 2546350:E1B03_RS16000
uniprot id: A0A4P6WS78
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

2546350:E1B03 RS08500
gene id: 2546350:E1B03_RS08500
uniprot id: A0A4P6WK31
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2546350:E1B03 RS20070
gene id: 2546350:E1B03_RS20070
uniprot id: A0A4P6WRY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2546350:E1B03 RS04425
gene id: 2546350:E1B03_RS04425
uniprot id: A0A4P6WII1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

2546350:E1B03 RS02355
gene id: 2546350:E1B03_RS02355
uniprot id: A0A4P6WIT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2546350:E1B03 RS08325
gene id: 2546350:E1B03_RS08325
uniprot id: A0A4P6WL77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

2546350:E1B03 RS00740
gene id: 2546350:E1B03_RS00740
uniprot id: A0A4P6WEM4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TraA family.
messages: Cell inner membrane
messages: Membrane
messages: Monomer. Interacts with itself to form filaments; also interacts with TraQ.
messages: Secreted

2546350:E1B03 RS11825
gene id: 2546350:E1B03_RS11825
uniprot id: A0A4P6WJY3
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

2546350:E1B03 RS05655
gene id: 2546350:E1B03_RS05655
uniprot id: A0A4V1A9T2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

2546350:E1B03 RS09720
gene id: 2546350:E1B03_RS09720
uniprot id: A0A4P6WP68
names: Similarity
messages: Belongs to the UPF0434 family.

2546350:E1B03 RS26130
gene id: 2546350:E1B03_RS26130
uniprot id: A0A4P6WQ54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

2546350:E1B03 RS14980
gene id: 2546350:E1B03_RS14980
uniprot id: A0A4P6WNG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

2546350:E1B03 RS24505
gene id: 2546350:E1B03_RS24505
uniprot id: A0A4P6WW77
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

2546350:E1B03 RS03860
gene id: 2546350:E1B03_RS03860
uniprot id: A0A4P6WJ23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Heterododecamer (2C3:3R2) of six catalytic PyrB chains organized as two trimers (C3), and six regulatory PyrI chains organized as three dimers (R2).
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

2546350:E1B03 RS00965
gene id: 2546350:E1B03_RS00965
uniprot id: A0A4V1A9J7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2546350:E1B03 RS17915
gene id: 2546350:E1B03_RS17915
uniprot id: A0A4P6WT91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

2546350:E1B03 RS16960
gene id: 2546350:E1B03_RS16960
uniprot id: A0A4P6WM85
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

2546350:E1B03 RS24065
gene id: 2546350:E1B03_RS24065
uniprot id: A0A4P6WW29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

2546350:E1B03 RS10565
gene id: 2546350:E1B03_RS10565
uniprot id: A0A4P6WJG1
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

2546350:E1B03 RS21890
gene id: 2546350:E1B03_RS21890
uniprot id: A0A4P6WN10
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2546350:E1B03 RS10815
gene id: 2546350:E1B03_RS10815
uniprot id: A0A4P6WPY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

2546350:E1B03 RS24100
gene id: 2546350:E1B03_RS24100
uniprot id: A0A4P6WTN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2546350:E1B03 RS08250
gene id: 2546350:E1B03_RS08250
uniprot id: A0A4V1A9Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

2546350:E1B03 RS03850
gene id: 2546350:E1B03_RS03850
uniprot id: A0A4P6WHM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

2546350:E1B03 RS06950
gene id: 2546350:E1B03_RS06950
uniprot id: A0A4P6WMK3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

2546350:E1B03 RS21345
gene id: 2546350:E1B03_RS21345
uniprot id: A0A4P6WSE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

2546350:E1B03 RS23660
gene id: 2546350:E1B03_RS23660
uniprot id: A0A4P6WVW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

2546350:E1B03 RS05015
gene id: 2546350:E1B03_RS05015
uniprot id: A0A4P6WLD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

2546350:E1B03 RS00565
gene id: 2546350:E1B03_RS00565
uniprot id: A0A4P6WI11
names: Function
names: Similarity
messages: Belongs to the FumD family.
messages: In vitro catalyzes the addition of water to fumarate, forming malate. Cannot catalyze the reverse reaction. Cannot use the cis-isomer maleate as substrate.

2546350:E1B03 RS06880
gene id: 2546350:E1B03_RS06880
uniprot id: A0A4P6WHK2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane
messages: The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains.

2546350:E1B03 RS23765
gene id: 2546350:E1B03_RS23765
uniprot id: A0A4P6WSR5
names: Similarity
messages: Belongs to the RNase E/G family. RNase G subfamily.

2546350:E1B03 RS18365
gene id: 2546350:E1B03_RS18365
uniprot id: A0A4P6WME8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2546350:E1B03 RS24955
gene id: 2546350:E1B03_RS24955
uniprot id: A0A4P6WQS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpB subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Proton-dependent permease that transports di- and tripeptides.

2546350:E1B03 RS20790
gene id: 2546350:E1B03_RS20790
uniprot id: A0A4P6WRB5
names: Similarity
messages: Belongs to the HupF/HypC family.

2546350:E1B03 RS11935
gene id: 2546350:E1B03_RS11935
uniprot id: A0A4P6WIP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2546350:E1B03 RS09600
gene id: 2546350:E1B03_RS09600
uniprot id: A0A4P6WJ11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

2546350:E1B03 RS04305
gene id: 2546350:E1B03_RS04305
uniprot id: A0A4P6WG67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Cell inner membrane
messages: Involved in succinate export with YjjP. Both proteins are required for export.
messages: Membrane
messages: The transporter is composed of YjjB and YjjP.

2546350:E1B03 RS24355
gene id: 2546350:E1B03_RS24355
uniprot id: A0A4P6WTP9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

2546350:E1B03 RS17690
gene id: 2546350:E1B03_RS17690
uniprot id: A0A4P6WM59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

2546350:E1B03 RS06790
gene id: 2546350:E1B03_RS06790
uniprot id: A0A4P6WMH7
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

2546350:E1B03 RS19830
gene id: 2546350:E1B03_RS19830
uniprot id: A0A4P6WQX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

2546350:E1B03 RS23330
gene id: 2546350:E1B03_RS23330
uniprot id: A0A4P6WNP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

2546350:E1B03 RS05335
gene id: 2546350:E1B03_RS05335
uniprot id: A0A4P6WIA7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2546350:E1B03 RS08875
gene id: 2546350:E1B03_RS08875
uniprot id: A0A4P6WK93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2546350:E1B03 RS23785
gene id: 2546350:E1B03_RS23785
uniprot id: A0A4V1AAR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

2546350:E1B03 RS01065
gene id: 2546350:E1B03_RS01065
uniprot id: A0A4V1A9J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

2546350:E1B03 RS02085
gene id: 2546350:E1B03_RS02085
uniprot id: A0A4V1A9L7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2546350:E1B03 RS09775
gene id: 2546350:E1B03_RS09775
uniprot id: A0A4P6WM11
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

2546350:E1B03 RS12600
gene id: 2546350:E1B03_RS12600
uniprot id: A0A4V1AA60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SlyA family.
messages: Homodimer.
messages: Transcription regulator that can specifically activate or repress expression of target genes.

2546350:E1B03 RS22580
gene id: 2546350:E1B03_RS22580
uniprot id: A0A4P6WVF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: Homooctamer.

2546350:E1B03 RS25260
gene id: 2546350:E1B03_RS25260
uniprot id: A0A4P6WQW3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2546350:E1B03 RS03680
gene id: 2546350:E1B03_RS03680
uniprot id: A0A4P6WF30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

2546350:E1B03 RS21020
gene id: 2546350:E1B03_RS21020
uniprot id: A0A4P6WMM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

2546350:E1B03 RS00985
gene id: 2546350:E1B03_RS00985
uniprot id: A0A4P6WES3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

2546350:E1B03 RS23775
gene id: 2546350:E1B03_RS23775
uniprot id: A0A4P6WVY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

2546350:E1B03 RS05010
gene id: 2546350:E1B03_RS05010
uniprot id: A0A4V1A9S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

2546350:E1B03 RS13365
gene id: 2546350:E1B03_RS13365
uniprot id: A0A4P6WMS8
names: Function
names: Similarity
messages: Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein.
messages: Belongs to the SRA family.

2546350:E1B03 RS03310
gene id: 2546350:E1B03_RS03310
uniprot id: A0A4P6WHD7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).

2546350:E1B03 RS02040
gene id: 2546350:E1B03_RS02040
uniprot id: A0A4P6WJT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

2546350:E1B03 RS04455
gene id: 2546350:E1B03_RS04455
uniprot id: A0A4P6WJP6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

2546350:E1B03 RS16605
gene id: 2546350:E1B03_RS16605
uniprot id: A0A4P6WKN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

2546350:E1B03 RS10595
gene id: 2546350:E1B03_RS10595
uniprot id: A0A4P6WL19
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2546350:E1B03 RS24035
gene id: 2546350:E1B03_RS24035
uniprot id: A0A4P6WTI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2546350:E1B03 RS22005
gene id: 2546350:E1B03_RS22005
uniprot id: A0A4V1AAN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Monomer.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

2546350:E1B03 RS23755
gene id: 2546350:E1B03_RS23755
uniprot id: A0A4P6WXG2
names: Function
names: Similarity
messages: Belongs to the peptidase U62 family.
messages: Metalloprotease involved in CcdA degradation. Suppresses the inhibitory activity of the carbon storage regulator (CsrA).

2546350:E1B03 RS01720
gene id: 2546350:E1B03_RS01720
uniprot id: A0A4V1A9L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

2546350:E1B03 RS25725
gene id: 2546350:E1B03_RS25725
uniprot id: A0A4P6WUE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

2546350:E1B03 RS24135
gene id: 2546350:E1B03_RS24135
uniprot id: A0A4P6WTK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2546350:E1B03 RS20765
gene id: 2546350:E1B03_RS20765
uniprot id: A0A4P6WUB6
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS25685
gene id: 2546350:E1B03_RS25685
uniprot id: A0A4P6WR28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

2546350:E1B03 RS04155
gene id: 2546350:E1B03_RS04155
uniprot id: A0A4P6WG39
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2546350:E1B03 RS03540
gene id: 2546350:E1B03_RS03540
uniprot id: A0A4P6WIX2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

2546350:E1B03 RS01530
gene id: 2546350:E1B03_RS01530
uniprot id: A0A4P6WKL5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

2546350:E1B03 RS05845
gene id: 2546350:E1B03_RS05845
uniprot id: A0A4P6WMN6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

2546350:E1B03 RS12625
gene id: 2546350:E1B03_RS12625
uniprot id: A0A4P6WNA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

2546350:E1B03 RS14175
gene id: 2546350:E1B03_RS14175
uniprot id: A0A4P6WN24
names: Similarity
messages: Belongs to the PspA/IM30 family.

2546350:E1B03 RS18630
gene id: 2546350:E1B03_RS18630
uniprot id: A0A4P6WR60
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M74 family.
messages: Binds 2 Zn(2+) ions per subunit. Zn(2+) ion 1 is bound in the active site. Zn(2+) ion 2 is bound at the dimer interface by residues from both subunits.
messages: Dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus.
messages: Periplasm

2546350:E1B03 RS09560
gene id: 2546350:E1B03_RS09560
uniprot id: A0A4V1AA05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2546350:E1B03 RS06885
gene id: 2546350:E1B03_RS06885
uniprot id: A0A4P6WN66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

2546350:E1B03 RS09750
gene id: 2546350:E1B03_RS09750
uniprot id: A0A4P6WJ39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukE family.
messages: Interacts, and probably forms a ternary complex, with MukF and MukB. The complex formation is stimulated by calcium or magnesium.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
messages: nucleoid

2546350:E1B03 RS15840
gene id: 2546350:E1B03_RS15840
uniprot id: A0A4P6WS53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism.

2546350:E1B03 RS02320
gene id: 2546350:E1B03_RS02320
uniprot id: A0A4P6WIC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2546350:E1B03 RS23680
gene id: 2546350:E1B03_RS23680
uniprot id: A0A4P6WVS1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2546350:E1B03 RS24140
gene id: 2546350:E1B03_RS24140
uniprot id: A0A4P6WSM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

2546350:E1B03 RS23850
gene id: 2546350:E1B03_RS23850
uniprot id: A0A4P6WTF7
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

2546350:E1B03 RS09295
gene id: 2546350:E1B03_RS09295
uniprot id: A0A4V1AA00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

2546350:E1B03 RS03930
gene id: 2546350:E1B03_RS03930
uniprot id: A0A4P6WG03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

2546350:E1B03 RS24650
gene id: 2546350:E1B03_RS24650
uniprot id: A0A4P6WPD2
names: Similarity
messages: Belongs to the pirin family.

2546350:E1B03 RS19355
gene id: 2546350:E1B03_RS19355
uniprot id: A0A4P6WRI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

2546350:E1B03 RS19875
gene id: 2546350:E1B03_RS19875
uniprot id: A0A4P6WN46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. SrmB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
messages: Interacts with the 50S ribosomal subunit.

2546350:E1B03 RS04445
gene id: 2546350:E1B03_RS04445
uniprot id: A0A4V1A9Q9
names: Similarity
messages: Belongs to the Smp family.

2546350:E1B03 RS09105
gene id: 2546350:E1B03_RS09105
uniprot id: A0A4P6WLQ4
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

2546350:E1B03 RS20530
gene id: 2546350:E1B03_RS20530
uniprot id: A0A4V1AAK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2546350:E1B03 RS11060
gene id: 2546350:E1B03_RS11060
uniprot id: A0A4P6WIC3
names: Similarity
messages: Belongs to the gns family.

2546350:E1B03 RS24095
gene id: 2546350:E1B03_RS24095
uniprot id: A0A4P6WPZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2546350:E1B03 RS02675
gene id: 2546350:E1B03_RS02675
uniprot id: A0A4V1A9M7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

2546350:E1B03 RS24110
gene id: 2546350:E1B03_RS24110
uniprot id: A0A4P6WQE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2546350:E1B03 RS10835
gene id: 2546350:E1B03_RS10835
uniprot id: A0A4P6WXB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

2546350:E1B03 RS22615
gene id: 2546350:E1B03_RS22615
uniprot id: A0A4P6WT04
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

2546350:E1B03 RS01920
gene id: 2546350:E1B03_RS01920
uniprot id: A0A4P6WE82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdgT transporter family.
messages: Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
messages: Cell membrane

2546350:E1B03 RS17750
gene id: 2546350:E1B03_RS17750
uniprot id: A0A4P6WPX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

2546350:E1B03 RS22260
gene id: 2546350:E1B03_RS22260
uniprot id: A0A4P6WS11
names: Similarity
messages: Belongs to the HupF/HypC family.

2546350:E1B03 RS12550
gene id: 2546350:E1B03_RS12550
uniprot id: A0A4V1AA59
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

2546350:E1B03 RS05285
gene id: 2546350:E1B03_RS05285
uniprot id: A0A4P6WI96
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

2546350:E1B03 RS13555
gene id: 2546350:E1B03_RS13555
uniprot id: A0A4P6WR59
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS17875
gene id: 2546350:E1B03_RS17875
uniprot id: A0A4P6WSX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2546350:E1B03 RS23460
gene id: 2546350:E1B03_RS23460
uniprot id: A0A4P6WVN4
names: Similarity
messages: Belongs to the BolA/IbaG family.

2546350:E1B03 RS24990
gene id: 2546350:E1B03_RS24990
uniprot id: A0A4P6WU22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

2546350:E1B03 RS04720
gene id: 2546350:E1B03_RS04720
uniprot id: A0A4P6WI02
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA.

2546350:E1B03 RS06935
gene id: 2546350:E1B03_RS06935
uniprot id: A0A4P6WN70
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2546350:E1B03 RS05385
gene id: 2546350:E1B03_RS05385
uniprot id: A0A4P6WIB9
names: Similarity
messages: Belongs to the skp family.

2546350:E1B03 RS22945
gene id: 2546350:E1B03_RS22945
uniprot id: A0A4P6WVK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Has been proposed to be a redox modulator.
messages: Membrane

2546350:E1B03 RS15330
gene id: 2546350:E1B03_RS15330
uniprot id: A0A4P6WNN8
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

2546350:E1B03 RS20760
gene id: 2546350:E1B03_RS20760
uniprot id: A0A4V1AAL1
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS23695
gene id: 2546350:E1B03_RS23695
uniprot id: A0A4P6WPT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS21380
gene id: 2546350:E1B03_RS21380
uniprot id: A0A4P6WMT8
names: Function
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

2546350:E1B03 RS02235
gene id: 2546350:E1B03_RS02235
uniprot id: A0A4P6WF72
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.

2546350:E1B03 RS04800
gene id: 2546350:E1B03_RS04800
uniprot id: A0A4P6WFK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

2546350:E1B03 RS15730
gene id: 2546350:E1B03_RS15730
uniprot id: A0A4P6WNX9
names: Similarity
messages: Belongs to the UPF0181 family.

2546350:E1B03 RS19580
gene id: 2546350:E1B03_RS19580
uniprot id: A0A4P6WNF8
names: Function
names: Similarity
messages: Belongs to the IscX family.
messages: May function as iron donor in the assembly of iron-sulfur clusters.

2546350:E1B03 RS17725
gene id: 2546350:E1B03_RS17725
uniprot id: A0A4P6WSU8
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS10485
gene id: 2546350:E1B03_RS10485
uniprot id: A0A4P6WKZ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2546350:E1B03 RS18750
gene id: 2546350:E1B03_RS18750
uniprot id: A0A4P6WMK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm

2546350:E1B03 RS01475
gene id: 2546350:E1B03_RS01475
uniprot id: A0A4P6WEV6
names: Similarity
messages: Belongs to the Rht family.

2546350:E1B03 RS18310
gene id: 2546350:E1B03_RS18310
uniprot id: A0A4P6WQ28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2546350:E1B03 RS17710
gene id: 2546350:E1B03_RS17710
uniprot id: A0A4P6WT57
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

2546350:E1B03 RS03395
gene id: 2546350:E1B03_RS03395
uniprot id: A0A4P6WFR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

2546350:E1B03 RS19410
gene id: 2546350:E1B03_RS19410
uniprot id: A0A4P6WQK1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

2546350:E1B03 RS24815
gene id: 2546350:E1B03_RS24815
uniprot id: A0A4V1AAT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Interacts with IscS.
messages: Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.

2546350:E1B03 RS24125
gene id: 2546350:E1B03_RS24125
uniprot id: A0A4V1AAS3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2546350:E1B03 RS06715
gene id: 2546350:E1B03_RS06715
uniprot id: A0A4P6WJK0
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

2546350:E1B03 RS24425
gene id: 2546350:E1B03_RS24425
uniprot id: A0A4P6WTT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

2546350:E1B03 RS25525
gene id: 2546350:E1B03_RS25525
uniprot id: A0A4P6WTI9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

2546350:E1B03 RS14405
gene id: 2546350:E1B03_RS14405
uniprot id: A0A4P6WJS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

2546350:E1B03 RS12175
gene id: 2546350:E1B03_RS12175
uniprot id: A0A4P6WN36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

2546350:E1B03 RS01035
gene id: 2546350:E1B03_RS01035
uniprot id: A0A4P6WET1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

2546350:E1B03 RS21045
gene id: 2546350:E1B03_RS21045
uniprot id: A0A4P6WNM2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

2546350:E1B03 RS01435
gene id: 2546350:E1B03_RS01435
uniprot id: A0A4P6WE11
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the top DNA strands.

2546350:E1B03 RS10945
gene id: 2546350:E1B03_RS10945
uniprot id: A0A4P6WQ03
names: Similarity
messages: Belongs to the ArsC family.

2546350:E1B03 RS21075
gene id: 2546350:E1B03_RS21075
uniprot id: A0A4V1AAL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

2546350:E1B03 RS05790
gene id: 2546350:E1B03_RS05790
uniprot id: A0A4P6WGV4
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

2546350:E1B03 RS04775
gene id: 2546350:E1B03_RS04775
uniprot id: A0A4P6WGJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.
messages: Cell inner membrane
messages: Homodimer. Interacts with KefC.
messages: Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC.

2546350:E1B03 RS07135
gene id: 2546350:E1B03_RS07135
uniprot id: A0A4P6WKM4
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

2546350:E1B03 RS20670
gene id: 2546350:E1B03_RS20670
uniprot id: A0A4P6WR47
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2546350:E1B03 RS24775
gene id: 2546350:E1B03_RS24775
uniprot id: A0A4P6WTY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

2546350:E1B03 RS09865
gene id: 2546350:E1B03_RS09865
uniprot id: A0A4V1AA11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

2546350:E1B03 RS22395
gene id: 2546350:E1B03_RS22395
uniprot id: A0A4P6WRV4
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

2546350:E1B03 RS16720
gene id: 2546350:E1B03_RS16720
uniprot id: A0A4P6WSE4
names: Similarity
messages: Belongs to the diol/glycerol dehydratase large subunit family.

2546350:E1B03 RS23290
gene id: 2546350:E1B03_RS23290
uniprot id: A0A4P6WT72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

2546350:E1B03 RS10570
gene id: 2546350:E1B03_RS10570
uniprot id: A0A4P6WPV7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2546350:E1B03 RS24820
gene id: 2546350:E1B03_RS24820
uniprot id: A0A4P6WWC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

2546350:E1B03 RS23515
gene id: 2546350:E1B03_RS23515
uniprot id: A0A4P6WTB0
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

2546350:E1B03 RS23670
gene id: 2546350:E1B03_RS23670
uniprot id: A0A4V1AAR5
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

2546350:E1B03 RS03305
gene id: 2546350:E1B03_RS03305
uniprot id: A0A4P6WJ82
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

2546350:E1B03 RS17685
gene id: 2546350:E1B03_RS17685
uniprot id: A0A4P6WPR9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS23480
gene id: 2546350:E1B03_RS23480
uniprot id: A0A4P6WTE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

2546350:E1B03 RS15660
gene id: 2546350:E1B03_RS15660
uniprot id: A0A4P6WNT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

2546350:E1B03 RS04975
gene id: 2546350:E1B03_RS04975
uniprot id: A0A4P6WI50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

2546350:E1B03 RS19390
gene id: 2546350:E1B03_RS19390
uniprot id: A0A4P6WM01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

2546350:E1B03 RS16455
gene id: 2546350:E1B03_RS16455
uniprot id: A0A4P6WP51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

2546350:E1B03 RS06820
gene id: 2546350:E1B03_RS06820
uniprot id: A0A4P6WHJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2546350:E1B03 RS09880
gene id: 2546350:E1B03_RS09880
uniprot id: A0A4P6WKQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MatP family.
messages: Cytoplasm
messages: Homodimer.
messages: Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.

2546350:E1B03 RS15810
gene id: 2546350:E1B03_RS15810
uniprot id: A0A4P6WPN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MgrB family.
messages: Cell membrane
messages: May form homooligomers. Probably interacts with the periplasmic domain of PhoQ.
messages: PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing. MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway. Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP.

2546350:E1B03 RS24230
gene id: 2546350:E1B03_RS24230
uniprot id: A0A4P6WW32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
messages: Cell inner membrane
messages: Interacts with the regulatory subunit KefG.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.

2546350:E1B03 RS06600
gene id: 2546350:E1B03_RS06600
uniprot id: A0A4P6WHD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

2546350:E1B03 RS01215
gene id: 2546350:E1B03_RS01215
uniprot id: A0A4P6WEV7
names: Similarity
messages: Belongs to the UPF0438 family.

2546350:E1B03 RS18320
gene id: 2546350:E1B03_RS18320
uniprot id: A0A4P6WQX0
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS23845
gene id: 2546350:E1B03_RS23845
uniprot id: A0A4P6WVV3
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

2546350:E1B03 RS04265
gene id: 2546350:E1B03_RS04265
uniprot id: A0A4P6WFB2
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS24060
gene id: 2546350:E1B03_RS24060
uniprot id: A0A4P6WQD6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2546350:E1B03 RS23710
gene id: 2546350:E1B03_RS23710
uniprot id: A0A4P6WQ89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

2546350:E1B03 RS09405
gene id: 2546350:E1B03_RS09405
uniprot id: A0A4P6WRF2
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

2546350:E1B03 RS05480
gene id: 2546350:E1B03_RS05480
uniprot id: A0A4P6WK42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RcsF family.
messages: Cell outer membrane
messages: Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects.

2546350:E1B03 RS00975
gene id: 2546350:E1B03_RS00975
uniprot id: A0A4P6WI82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

2546350:E1B03 RS01275
gene id: 2546350:E1B03_RS01275
uniprot id: A0A4P6WH13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

2546350:E1B03 RS13620
gene id: 2546350:E1B03_RS13620
uniprot id: A0A4P6WQY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GhoT/OrtT toxin family.
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS15965
gene id: 2546350:E1B03_RS15965
uniprot id: A0A4P6WS20
names: Similarity
messages: Belongs to the pyruvate kinase family.

2546350:E1B03 RS01990
gene id: 2546350:E1B03_RS01990
uniprot id: A0A4P6WJS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

2546350:E1B03 RS23395
gene id: 2546350:E1B03_RS23395
uniprot id: A0A4V1AAR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

2546350:E1B03 RS06995
gene id: 2546350:E1B03_RS06995
uniprot id: A0A4V1A9V8
names: Similarity
messages: Belongs to the P(II) protein family.

2546350:E1B03 RS25670
gene id: 2546350:E1B03_RS25670
uniprot id: A0A4P6WWW8
names: Similarity
messages: Belongs to the YicC/YloC family.

2546350:E1B03 RS23180
gene id: 2546350:E1B03_RS23180
uniprot id: A0A4P6WVI5
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS08715
gene id: 2546350:E1B03_RS08715
uniprot id: A0A4P6WK65
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

2546350:E1B03 RS09785
gene id: 2546350:E1B03_RS09785
uniprot id: A0A4P6WIR4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

2546350:E1B03 RS20055
gene id: 2546350:E1B03_RS20055
uniprot id: A0A4P6WRW1
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS19385
gene id: 2546350:E1B03_RS19385
uniprot id: A0A4P6WTY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2546350:E1B03 RS09585
gene id: 2546350:E1B03_RS09585
uniprot id: A0A4P6WIN0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

2546350:E1B03 RS16480
gene id: 2546350:E1B03_RS16480
uniprot id: A0A4P6WSF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Required for the assembly of the rivet at the earliest stage of flagellar biosynthesis.
messages: Role in flagellar biosynthesis.

2546350:E1B03 RS04945
gene id: 2546350:E1B03_RS04945
uniprot id: A0A4P6WGI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.
messages: nucleoid

2546350:E1B03 RS05005
gene id: 2546350:E1B03_RS05005
uniprot id: A0A4P6WFN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2546350:E1B03 RS09610
gene id: 2546350:E1B03_RS09610
uniprot id: A0A4P6WHQ9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2546350:E1B03 RS20455
gene id: 2546350:E1B03_RS20455
uniprot id: A0A4P6WR71
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

2546350:E1B03 RS20035
gene id: 2546350:E1B03_RS20035
uniprot id: A0A4P6WMA1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

2546350:E1B03 RS24395
gene id: 2546350:E1B03_RS24395
uniprot id: A0A4P6WP74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

2546350:E1B03 RS23745
gene id: 2546350:E1B03_RS23745
uniprot id: A0A4P6WSH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AaeX family.
messages: Cell membrane

2546350:E1B03 RS23220
gene id: 2546350:E1B03_RS23220
uniprot id: A0A4P6WVP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

2546350:E1B03 RS19610
gene id: 2546350:E1B03_RS19610
uniprot id: A0A4P6WQN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

2546350:E1B03 RS02015
gene id: 2546350:E1B03_RS02015
uniprot id: A0A4P6WHC3
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activity of this regulatory enzyme is affected by several metabolites. Allosterically and non-competitively inhibited by fructose 1,6-bisphosphate (FBP) and unphosphorylated phosphocarrier protein EIIA-Glc (III-Glc), an integral component of the bacterial phosphotransferase (PTS) system.
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium). Heterodimer with EIIA-Glc. Binds 1 zinc ion per glycerol kinase EIIA-Glc dimer. The zinc ion is important for dimerization.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

2546350:E1B03 RS06025
gene id: 2546350:E1B03_RS06025
uniprot id: A0A4P6WIM7
names: Similarity
messages: Belongs to the UPF0386 family.

2546350:E1B03 RS17655
gene id: 2546350:E1B03_RS17655
uniprot id: A0A4P6WMI3
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS10625
gene id: 2546350:E1B03_RS10625
uniprot id: A0A4P6WI69
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

2546350:E1B03 RS03750
gene id: 2546350:E1B03_RS03750
uniprot id: A0A4P6WHK7
names: Similarity
messages: Belongs to the UPF0307 family.

2546350:E1B03 RS08570
gene id: 2546350:E1B03_RS08570
uniprot id: A0A4P6WKF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Homodimer. Polymerizes to form helical filaments.
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

2546350:E1B03 RS05355
gene id: 2546350:E1B03_RS05355
uniprot id: A0A4P6WGN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

2546350:E1B03 RS07130
gene id: 2546350:E1B03_RS07130
uniprot id: A0A4P6WHL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

2546350:E1B03 RS14140
gene id: 2546350:E1B03_RS14140
uniprot id: A0A4P6WJN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2546350:E1B03 RS25225
gene id: 2546350:E1B03_RS25225
uniprot id: A0A4P6WQW1
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS23730
gene id: 2546350:E1B03_RS23730
uniprot id: A0A4V1AAR6
names: Similarity
messages: Belongs to the barstar family.

2546350:E1B03 RS18405
gene id: 2546350:E1B03_RS18405
uniprot id: A0A4P6WT65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

2546350:E1B03 RS08850
gene id: 2546350:E1B03_RS08850
uniprot id: A0A4P6WP25
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

2546350:E1B03 RS01825
gene id: 2546350:E1B03_RS01825
uniprot id: A0A4V1A9L2
names: Cofactor
names: Function
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

2546350:E1B03 RS08970
gene id: 2546350:E1B03_RS08970
uniprot id: A0A4P6WIQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.
messages: Belongs to the AcrZ family.
messages: Cell membrane
messages: Part of the AcrA-AcrB-AcrZ-TolC efflux pump, interacts directly with AcrB.

2546350:E1B03 RS12690
gene id: 2546350:E1B03_RS12690
uniprot id: A0A4P6WQR9
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

2546350:E1B03 RS24620
gene id: 2546350:E1B03_RS24620
uniprot id: A0A4P6WQ91
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2546350:E1B03 RS22350
gene id: 2546350:E1B03_RS22350
uniprot id: A0A4P6WP70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS05390
gene id: 2546350:E1B03_RS05390
uniprot id: A0A4P6WGT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

2546350:E1B03 RS03260
gene id: 2546350:E1B03_RS03260
uniprot id: A0A4P6WHC8
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

2546350:E1B03 RS16475
gene id: 2546350:E1B03_RS16475
uniprot id: A0A4P6WM09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

2546350:E1B03 RS20640
gene id: 2546350:E1B03_RS20640
uniprot id: A0A4P6WNV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

2546350:E1B03 RS01450
gene id: 2546350:E1B03_RS01450
uniprot id: A0A4P6WIF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

2546350:E1B03 RS04735
gene id: 2546350:E1B03_RS04735
uniprot id: A0A4P6WIN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA.
messages: Cytoplasm
messages: Homotetramer.

2546350:E1B03 RS25505
gene id: 2546350:E1B03_RS25505
uniprot id: A0A4P6WUB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

2546350:E1B03 RS18675
gene id: 2546350:E1B03_RS18675
uniprot id: A0A4P6WTA7
names: Similarity
messages: Belongs to the MlaA family.

2546350:E1B03 RS16040
gene id: 2546350:E1B03_RS16040
uniprot id: A0A4P6WP38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

2546350:E1B03 RS16710
gene id: 2546350:E1B03_RS16710
uniprot id: A0A4P6WKQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the bacterial microcompartments protein family.
messages: The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.

2546350:E1B03 RS17315
gene id: 2546350:E1B03_RS17315
uniprot id: A0A4P6WPQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2546350:E1B03 RS14915
gene id: 2546350:E1B03_RS14915
uniprot id: A0A4P6WNI3
names: Similarity
messages: Belongs to the UPF0162 family.

2546350:E1B03 RS00510
gene id: 2546350:E1B03_RS00510
uniprot id: A0A4P6WEI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

2546350:E1B03 RS20020
gene id: 2546350:E1B03_RS20020
uniprot id: A0A4P6WR01
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2546350:E1B03 RS23440
gene id: 2546350:E1B03_RS23440
uniprot id: A0A4P6WQ47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2546350:E1B03 RS22550
gene id: 2546350:E1B03_RS22550
uniprot id: A0A4P6WSU9
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

2546350:E1B03 RS17980
gene id: 2546350:E1B03_RS17980
uniprot id: A0A4P6WLB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

2546350:E1B03 RS18265
gene id: 2546350:E1B03_RS18265
uniprot id: A0A4P6WMD3
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2546350:E1B03 RS05325
gene id: 2546350:E1B03_RS05325
uniprot id: A0A4P6WLJ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

2546350:E1B03 RS19340
gene id: 2546350:E1B03_RS19340
uniprot id: A0A4P6WLZ0
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS19955
gene id: 2546350:E1B03_RS19955
uniprot id: A0A4P6WN56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

2546350:E1B03 RS17305
gene id: 2546350:E1B03_RS17305
uniprot id: A0A4P6WLZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

2546350:E1B03 RS21935
gene id: 2546350:E1B03_RS21935
uniprot id: A0A4P6WV59
names: Function
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.
messages: Catalyzes the formation of putrescine from agmatine.

2546350:E1B03 RS06280
gene id: 2546350:E1B03_RS06280
uniprot id: A0A4P6WIR5
names: Similarity
messages: Belongs to the UPF0386 family.

2546350:E1B03 RS03300
gene id: 2546350:E1B03_RS03300
uniprot id: A0A4P6WKL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdC family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

2546350:E1B03 RS15795
gene id: 2546350:E1B03_RS15795
uniprot id: A0A4P6WKB3
names: Subcellular Location Annotation
messages: Cytoplasm

2546350:E1B03 RS03725
gene id: 2546350:E1B03_RS03725
uniprot id: A0A4P6WLP6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS11365
gene id: 2546350:E1B03_RS11365
uniprot id: A0A4P6WLU7
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

2546350:E1B03 RS04635
gene id: 2546350:E1B03_RS04635
uniprot id: A0A4P6WIL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

2546350:E1B03 RS23835
gene id: 2546350:E1B03_RS23835
uniprot id: A0A4P6WNX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

2546350:E1B03 RS08205
gene id: 2546350:E1B03_RS08205
uniprot id: A0A4P6WN85
names: Similarity
messages: Belongs to the universal stress protein A family.

2546350:E1B03 RS21580
gene id: 2546350:E1B03_RS21580
uniprot id: A0A4P6WNU0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2546350:E1B03 RS07005
gene id: 2546350:E1B03_RS07005
uniprot id: A0A4P6WKR8
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

2546350:E1B03 RS15770
gene id: 2546350:E1B03_RS15770
uniprot id: A0A4P6WLC0
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS10365
gene id: 2546350:E1B03_RS10365
uniprot id: A0A4P6WPH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. OpgH subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
messages: Membrane

2546350:E1B03 RS08515
gene id: 2546350:E1B03_RS08515
uniprot id: A0A4P6WKE7
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

2546350:E1B03 RS22285
gene id: 2546350:E1B03_RS22285
uniprot id: A0A4P6WV38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

2546350:E1B03 RS16345
gene id: 2546350:E1B03_RS16345
uniprot id: A0A4P6WPX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2546350:E1B03 RS01390
gene id: 2546350:E1B03_RS01390
uniprot id: A0A4P6WUL5
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

2546350:E1B03 RS02815
gene id: 2546350:E1B03_RS02815
uniprot id: A0A4P6WIK9
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS06875
gene id: 2546350:E1B03_RS06875
uniprot id: A0A4P6WJM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

2546350:E1B03 RS25625
gene id: 2546350:E1B03_RS25625
uniprot id: A0A4P6WR19
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2546350:E1B03 RS12005
gene id: 2546350:E1B03_RS12005
uniprot id: A0A4P6WLX0
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

2546350:E1B03 RS16795
gene id: 2546350:E1B03_RS16795
uniprot id: A0A4P6WPG1
names: Function
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.

2546350:E1B03 RS22335
gene id: 2546350:E1B03_RS22335
uniprot id: A0A4P6WV52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

2546350:E1B03 RS08330
gene id: 2546350:E1B03_RS08330
uniprot id: A0A4P6WKB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

2546350:E1B03 RS04670
gene id: 2546350:E1B03_RS04670
uniprot id: A0A4P6WHZ4
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS16765
gene id: 2546350:E1B03_RS16765
uniprot id: A0A4V1AAD7
names: Similarity
messages: Belongs to the CcmL/EutN family.

2546350:E1B03 RS23235
gene id: 2546350:E1B03_RS23235
uniprot id: A0A4P6WVJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SIS family. DiaA subfamily.
messages: Homotetramer; dimer of dimers.
messages: Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.

2546350:E1B03 RS03425
gene id: 2546350:E1B03_RS03425
uniprot id: A0A4P6WHF1
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity.

2546350:E1B03 RS01570
gene id: 2546350:E1B03_RS01570
uniprot id: A0A4P6WH59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

2546350:E1B03 RS14740
gene id: 2546350:E1B03_RS14740
uniprot id: A0A4P6WP63
names: Similarity
messages: Belongs to the UPF0263 family.

2546350:E1B03 RS04610
gene id: 2546350:E1B03_RS04610
uniprot id: A0A4P6WJR3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2546350:E1B03 RS04825
gene id: 2546350:E1B03_RS04825
uniprot id: A0A4P6WGJ9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2546350:E1B03 RS24910
gene id: 2546350:E1B03_RS24910
uniprot id: A0A4P6WPI0
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS08315
gene id: 2546350:E1B03_RS08315
uniprot id: A0A4P6WJZ6
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

2546350:E1B03 RS09255
gene id: 2546350:E1B03_RS09255
uniprot id: A0A4P6WLS8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2546350:E1B03 RS09270
gene id: 2546350:E1B03_RS09270
uniprot id: A0A4P6WLM6
names: Similarity
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpX family.

2546350:E1B03 RS03855
gene id: 2546350:E1B03_RS03855
uniprot id: A0A4P6WG51
names: Similarity
names: Subunit
messages: Belongs to the RutC family.
messages: Homotrimer.

2546350:E1B03 RS21570
gene id: 2546350:E1B03_RS21570
uniprot id: A0A4P6WSG6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

2546350:E1B03 RS01300
gene id: 2546350:E1B03_RS01300
uniprot id: A0A4V1A9K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

2546350:E1B03 RS03720
gene id: 2546350:E1B03_RS03720
uniprot id: A0A4P6WFX3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS03490
gene id: 2546350:E1B03_RS03490
uniprot id: A0A4P6WI37
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Represses ulaG and the ulaABCDEF operon.

2546350:E1B03 RS00320
gene id: 2546350:E1B03_RS00320
uniprot id: A0A4V1A9I5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2546350:E1B03 RS02325
gene id: 2546350:E1B03_RS02325
uniprot id: A0A4P6WHG3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2546350:E1B03 RS09695
gene id: 2546350:E1B03_RS09695
uniprot id: A0A4P6WL57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2546350:E1B03 RS02435
gene id: 2546350:E1B03_RS02435
uniprot id: A0A4P6WL09
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2546350:E1B03 RS03225
gene id: 2546350:E1B03_RS03225
uniprot id: A0A4P6WFM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2546350:E1B03 RS18015
gene id: 2546350:E1B03_RS18015
uniprot id: A0A4P6WQ20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

2546350:E1B03 RS02735
gene id: 2546350:E1B03_RS02735
uniprot id: A0A4P6WKB9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class B bacterial acid phosphatase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homotetramer.
messages: Periplasm

2546350:E1B03 RS19070
gene id: 2546350:E1B03_RS19070
uniprot id: A0A4P6WN69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

2546350:E1B03 RS03390
gene id: 2546350:E1B03_RS03390
uniprot id: A0A4P6WI21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

2546350:E1B03 RS01090
gene id: 2546350:E1B03_RS01090
uniprot id: A0A4P6WHT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

2546350:E1B03 RS14360
gene id: 2546350:E1B03_RS14360
uniprot id: A0A4P6WNZ7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2546350:E1B03 RS08195
gene id: 2546350:E1B03_RS08195
uniprot id: A0A4P6WH43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

2546350:E1B03 RS04595
gene id: 2546350:E1B03_RS04595
uniprot id: A0A4P6WFG5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

2546350:E1B03 RS23900
gene id: 2546350:E1B03_RS23900
uniprot id: A0A4P6WTG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS24310
gene id: 2546350:E1B03_RS24310
uniprot id: A0A4P6WQ34
names: Similarity
messages: Belongs to the UPF0270 family.

2546350:E1B03 RS03895
gene id: 2546350:E1B03_RS03895
uniprot id: A0A4V1A9P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

2546350:E1B03 RS03370
gene id: 2546350:E1B03_RS03370
uniprot id: A0A4P6WJ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

2546350:E1B03 RS06765
gene id: 2546350:E1B03_RS06765
uniprot id: A0A4P6WJK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.
messages: Cell outer membrane

2546350:E1B03 RS03255
gene id: 2546350:E1B03_RS03255
uniprot id: A0A4P6WJ74
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

2546350:E1B03 RS21815
gene id: 2546350:E1B03_RS21815
uniprot id: A0A4P6WPD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

2546350:E1B03 RS03135
gene id: 2546350:E1B03_RS03135
uniprot id: A0A4P6WFS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

2546350:E1B03 RS02340
gene id: 2546350:E1B03_RS02340
uniprot id: A0A4P6WEE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

2546350:E1B03 RS04640
gene id: 2546350:E1B03_RS04640
uniprot id: A0A4P6WGD4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2546350:E1B03 RS01070
gene id: 2546350:E1B03_RS01070
uniprot id: A0A4P6WJ70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

2546350:E1B03 RS05960
gene id: 2546350:E1B03_RS05960
uniprot id: A0A4P6WLV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

2546350:E1B03 RS15765
gene id: 2546350:E1B03_RS15765
uniprot id: A0A4P6WNV4
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS02375
gene id: 2546350:E1B03_RS02375
uniprot id: A0A4P6WHH1
names: Subcellular Location Annotation
messages: Cytoplasm

2546350:E1B03 RS08280
gene id: 2546350:E1B03_RS08280
uniprot id: A0A4P6WKA4
names: Subcellular Location Annotation
messages: Cytoplasm

2546350:E1B03 RS14905
gene id: 2546350:E1B03_RS14905
uniprot id: A0A4P6WRL1
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS15300
gene id: 2546350:E1B03_RS15300
uniprot id: A0A4P6WLG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2546350:E1B03 RS12545
gene id: 2546350:E1B03_RS12545
uniprot id: A0A4P6WIX8
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.
messages: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters.

2546350:E1B03 RS24950
gene id: 2546350:E1B03_RS24950
uniprot id: A0A4P6WT89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm
messages: Required for resistance to DNA-damaging agents.

2546350:E1B03 RS21965
gene id: 2546350:E1B03_RS21965
uniprot id: A0A4P6WSL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS01240
gene id: 2546350:E1B03_RS01240
uniprot id: A0A4P6WDY0
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

2546350:E1B03 RS02695
gene id: 2546350:E1B03_RS02695
uniprot id: A0A4P6WH35
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

2546350:E1B03 RS08545
gene id: 2546350:E1B03_RS08545
uniprot id: A0A4P6WLG7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

2546350:E1B03 RS20095
gene id: 2546350:E1B03_RS20095
uniprot id: A0A4V1AAJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2546350:E1B03 RS21945
gene id: 2546350:E1B03_RS21945
uniprot id: A0A4V1AAN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgB family.
messages: Cytoplasm

2546350:E1B03 RS11660
gene id: 2546350:E1B03_RS11660
uniprot id: A0A4P6WQC1
names: Similarity
messages: Belongs to the asparaginase 1 family.

2546350:E1B03 RS15665
gene id: 2546350:E1B03_RS15665
uniprot id: A0A4P6WLA3
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

2546350:E1B03 RS23540
gene id: 2546350:E1B03_RS23540
uniprot id: A0A4P6WQ63
names: Subcellular Location Annotation
messages: Cytoplasm

2546350:E1B03 RS23550
gene id: 2546350:E1B03_RS23550
uniprot id: A0A4P6WNS7
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

2546350:E1B03 RS08830
gene id: 2546350:E1B03_RS08830
uniprot id: A0A4P6WUT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS16630
gene id: 2546350:E1B03_RS16630
uniprot id: A0A4P6WP79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

2546350:E1B03 RS19825
gene id: 2546350:E1B03_RS19825
uniprot id: A0A4P6WRU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

2546350:E1B03 RS06530
gene id: 2546350:E1B03_RS06530
uniprot id: A0A4V1A9U9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

2546350:E1B03 RS08395
gene id: 2546350:E1B03_RS08395
uniprot id: A0A4P6WH75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2546350:E1B03 RS16365
gene id: 2546350:E1B03_RS16365
uniprot id: A0A4P6WP91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

2546350:E1B03 RS00610
gene id: 2546350:E1B03_RS00610
uniprot id: A0A4P6WDL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TraT lipoprotein family.
messages: Cell outer membrane
messages: Membrane
messages: Responsible for preventing unproductive conjugation between bacteria carrying like plasmids.

2546350:E1B03 RS07055
gene id: 2546350:E1B03_RS07055
uniprot id: A0A4V1A9V9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

2546350:E1B03 RS06800
gene id: 2546350:E1B03_RS06800
uniprot id: A0A4P6WJ34
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

2546350:E1B03 RS23965
gene id: 2546350:E1B03_RS23965
uniprot id: A0A4P6WW12
names: Similarity
messages: Belongs to the Smg family.

2546350:E1B03 RS04615
gene id: 2546350:E1B03_RS04615
uniprot id: A0A4P6WHY5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

2546350:E1B03 RS05110
gene id: 2546350:E1B03_RS05110
uniprot id: A0A4P6WFQ6
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

2546350:E1B03 RS04600
gene id: 2546350:E1B03_RS04600
uniprot id: A0A4V1A9R2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

2546350:E1B03 RS00325
gene id: 2546350:E1B03_RS00325
uniprot id: A0A4P6WIL4
names: Similarity
messages: Belongs to the ArsC family.

2546350:E1B03 RS02365
gene id: 2546350:E1B03_RS02365
uniprot id: A0A4P6WFE5
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

2546350:E1B03 RS09120
gene id: 2546350:E1B03_RS09120
uniprot id: A0A4P6WLK5
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

2546350:E1B03 RS24025
gene id: 2546350:E1B03_RS24025
uniprot id: A0A4V1AAS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

2546350:E1B03 RS09260
gene id: 2546350:E1B03_RS09260
uniprot id: A0A4P6WKF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Dps family.
messages: Cytoplasm
messages: During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
messages: Homododecamer. The 12 subunits form a hollow sphere into which the mineral iron core of up to 500 Fe(3+) can be deposited.

2546350:E1B03 RS10560
gene id: 2546350:E1B03_RS10560
uniprot id: A0A4P6WLI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

2546350:E1B03 RS05420
gene id: 2546350:E1B03_RS05420
uniprot id: A0A4V1A9S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

2546350:E1B03 RS12045
gene id: 2546350:E1B03_RS12045
uniprot id: A0A4P6WQA0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2546350:E1B03 RS18330
gene id: 2546350:E1B03_RS18330
uniprot id: A0A4P6WMU8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2546350:E1B03 RS24765
gene id: 2546350:E1B03_RS24765
uniprot id: A0A4V1AAT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

2546350:E1B03 RS24720
gene id: 2546350:E1B03_RS24720
uniprot id: A0A4P6WTX1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

2546350:E1B03 RS17200
gene id: 2546350:E1B03_RS17200
uniprot id: A0A4P6WPI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

2546350:E1B03 RS19585
gene id: 2546350:E1B03_RS19585
uniprot id: A0A4P6WU24
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

2546350:E1B03 RS17130
gene id: 2546350:E1B03_RS17130
uniprot id: A0A4V1AAE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

2546350:E1B03 RS16430
gene id: 2546350:E1B03_RS16430
uniprot id: A0A4P6WSE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2546350:E1B03 RS03550
gene id: 2546350:E1B03_RS03550
uniprot id: A0A4P6WFT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

2546350:E1B03 RS24055
gene id: 2546350:E1B03_RS24055
uniprot id: A0A4P6WSU6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2546350:E1B03 RS18475
gene id: 2546350:E1B03_RS18475
uniprot id: A0A4P6WQZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

2546350:E1B03 RS09955
gene id: 2546350:E1B03_RS09955
uniprot id: A0A4P6WPL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Interacts with the TusBCD complex. Interacts with MnmA.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD.

2546350:E1B03 RS21940
gene id: 2546350:E1B03_RS21940
uniprot id: A0A4P6WN17
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

2546350:E1B03 RS07060
gene id: 2546350:E1B03_RS07060
uniprot id: A0A4P6WMM3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2546350:E1B03 RS02055
gene id: 2546350:E1B03_RS02055
uniprot id: A0A4P6WF97
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

2546350:E1B03 RS00355
gene id: 2546350:E1B03_RS00355
uniprot id: A0A4P6WED1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2546350:E1B03 RS24745
gene id: 2546350:E1B03_RS24745
uniprot id: A0A4P6WQP1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS02360
gene id: 2546350:E1B03_RS02360
uniprot id: A0A4P6WGY2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2546350:E1B03 RS23990
gene id: 2546350:E1B03_RS23990
uniprot id: A0A4P6WSK2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS12855
gene id: 2546350:E1B03_RS12855
uniprot id: A0A4P6WJ35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
messages: Catalyzes the excretion of spermidine.
messages: Cell membrane
messages: Forms a complex with MdtJ.
messages: Membrane

2546350:E1B03 RS18315
gene id: 2546350:E1B03_RS18315
uniprot id: A0A4P6WME0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4 family.
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Membrane

2546350:E1B03 RS10500
gene id: 2546350:E1B03_RS10500
uniprot id: A0A4P6WLI0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

2546350:E1B03 RS07120
gene id: 2546350:E1B03_RS07120
uniprot id: A0A4P6WKT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

2546350:E1B03 RS10755
gene id: 2546350:E1B03_RS10755
uniprot id: A0A4P6WJJ1
names: Similarity
messages: Belongs to the UPF0227 family.

2546350:E1B03 RS19810
gene id: 2546350:E1B03_RS19810
uniprot id: A0A4P6WQG8
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

2546350:E1B03 RS24030
gene id: 2546350:E1B03_RS24030
uniprot id: A0A4P6WVZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2546350:E1B03 RS24050
gene id: 2546350:E1B03_RS24050
uniprot id: A0A4P6WTM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2546350:E1B03 RS16315
gene id: 2546350:E1B03_RS16315
uniprot id: A0A4P6WP81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

2546350:E1B03 RS19850
gene id: 2546350:E1B03_RS19850
uniprot id: A0A4V1AAJ5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2546350:E1B03 RS14420
gene id: 2546350:E1B03_RS14420
uniprot id: A0A4P6WRC9
names: Similarity
messages: Belongs to the YciI family.

2546350:E1B03 RS21290
gene id: 2546350:E1B03_RS21290
uniprot id: A0A4P6WSD9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.

2546350:E1B03 RS05820
gene id: 2546350:E1B03_RS05820
uniprot id: A0A4P6WIJ0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

2546350:E1B03 RS24105
gene id: 2546350:E1B03_RS24105
uniprot id: A0A4P6WSV3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2546350:E1B03 RS14735
gene id: 2546350:E1B03_RS14735
uniprot id: A0A4P6WRI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

2546350:E1B03 RS08965
gene id: 2546350:E1B03_RS08965
uniprot id: A0A4P6WKM0
names: Similarity
messages: Belongs to the ModE family.

2546350:E1B03 RS22600
gene id: 2546350:E1B03_RS22600
uniprot id: A0A4P6WSV7
names: Similarity
messages: Belongs to the class-I fumarase family.

2546350:E1B03 RS03415
gene id: 2546350:E1B03_RS03415
uniprot id: A0A4P6WKN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

2546350:E1B03 RS21350
gene id: 2546350:E1B03_RS21350
uniprot id: A0A4P6WRE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

2546350:E1B03 RS03705
gene id: 2546350:E1B03_RS03705
uniprot id: A0A4P6WG26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

2546350:E1B03 RS16460
gene id: 2546350:E1B03_RS16460
uniprot id: A0A4P6WLK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2546350:E1B03 RS05320
gene id: 2546350:E1B03_RS05320
uniprot id: A0A4V1A9S6
names: Similarity
messages: Belongs to the UPF0325 family.

2546350:E1B03 RS20080
gene id: 2546350:E1B03_RS20080
uniprot id: A0A4P6WNN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

2546350:E1B03 RS08860
gene id: 2546350:E1B03_RS08860
uniprot id: A0A4V1A9Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2546350:E1B03 RS20025
gene id: 2546350:E1B03_RS20025
uniprot id: A0A4P6WNM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

2546350:E1B03 RS08815
gene id: 2546350:E1B03_RS08815
uniprot id: A0A4P6WLK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

2546350:E1B03 RS24315
gene id: 2546350:E1B03_RS24315
uniprot id: A0A4P6WTS0
names: Similarity
messages: Belongs to the phosphoribulokinase family.

2546350:E1B03 RS03265
gene id: 2546350:E1B03_RS03265
uniprot id: A0A4P6WFU6
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

2546350:E1B03 RS21875
gene id: 2546350:E1B03_RS21875
uniprot id: A0A4P6WRQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
messages: Cell membrane
messages: Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine.
messages: Membrane

2546350:E1B03 RS16745
gene id: 2546350:E1B03_RS16745
uniprot id: A0A4P6WPF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the bacterial microcompartments protein family.
messages: The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.

2546350:E1B03 RS25105
gene id: 2546350:E1B03_RS25105
uniprot id: A0A4P6WU56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

2546350:E1B03 RS23815
gene id: 2546350:E1B03_RS23815
uniprot id: A0A4P6WTJ3
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

2546350:E1B03 RS18605
gene id: 2546350:E1B03_RS18605
uniprot id: A0A4P6WMZ6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

2546350:E1B03 RS21760
gene id: 2546350:E1B03_RS21760
uniprot id: A0A4P6WPC7
names: Function
names: Similarity
messages: Belongs to the N(4)-acetylcytidine amidohydrolase family.
messages: Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).

2546350:E1B03 RS06625
gene id: 2546350:E1B03_RS06625
uniprot id: A0A4P6WGE9
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

2546350:E1B03 RS00485
gene id: 2546350:E1B03_RS00485
uniprot id: A0A4P6WDJ2
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

2546350:E1B03 RS00505
gene id: 2546350:E1B03_RS00505
uniprot id: A0A4P6WG13
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2546350:E1B03 RS11955
gene id: 2546350:E1B03_RS11955
uniprot id: A0A4P6WLW0
names: Similarity
messages: Belongs to the peptidase C40 family.

2546350:E1B03 RS25740
gene id: 2546350:E1B03_RS25740
uniprot id: A0A4P6WUH1
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

2546350:E1B03 RS05180
gene id: 2546350:E1B03_RS05180
uniprot id: A0A4P6WI81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS20525
gene id: 2546350:E1B03_RS20525
uniprot id: A0A4P6WMF8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2546350:E1B03 RS05350
gene id: 2546350:E1B03_RS05350
uniprot id: A0A4P6WIW9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2546350:E1B03 RS19650
gene id: 2546350:E1B03_RS19650
uniprot id: A0A4P6WTS8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS14410
gene id: 2546350:E1B03_RS14410
uniprot id: A0A4V1AA94
names: Function
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.
messages: Catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA.

2546350:E1B03 RS18375
gene id: 2546350:E1B03_RS18375
uniprot id: A0A4P6WQ86
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2546350:E1B03 RS01605
gene id: 2546350:E1B03_RS01605
uniprot id: A0A4P6WGK3
names: Similarity
messages: Belongs to the IMPACT family.

2546350:E1B03 RS00495
gene id: 2546350:E1B03_RS00495
uniprot id: A0A4P6WIP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

2546350:E1B03 RS14280
gene id: 2546350:E1B03_RS14280
uniprot id: A0A4P6WL16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapA family.
messages: Cell inner membrane
messages: Involved in the assembly of lipopolysaccharide (LPS).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2546350:E1B03 RS16415
gene id: 2546350:E1B03_RS16415
uniprot id: A0A4P6WQ23
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

2546350:E1B03 RS25705
gene id: 2546350:E1B03_RS25705
uniprot id: A0A4P6WWV0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

2546350:E1B03 RS01520
gene id: 2546350:E1B03_RS01520
uniprot id: A0A4P6WH51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate.
messages: Cytoplasm

2546350:E1B03 RS15760
gene id: 2546350:E1B03_RS15760
uniprot id: A0A4P6WPM6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

2546350:E1B03 RS03200
gene id: 2546350:E1B03_RS03200
uniprot id: A0A4P6WJ65
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CutA family.
messages: Binds 1 copper ion per subunit.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in resistance toward heavy metals.

2546350:E1B03 RS11045
gene id: 2546350:E1B03_RS11045
uniprot id: A0A4P6WJN0
names: Subcellular Location Annotation
messages: Cytoplasm

2546350:E1B03 RS24070
gene id: 2546350:E1B03_RS24070
uniprot id: A0A4P6WP11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

2546350:E1B03 RS21885
gene id: 2546350:E1B03_RS21885
uniprot id: A0A4P6WV48
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

2546350:E1B03 RS19615
gene id: 2546350:E1B03_RS19615
uniprot id: A0A4P6WMZ1
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster.
messages: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.

2546350:E1B03 RS05445
gene id: 2546350:E1B03_RS05445
uniprot id: A0A4P6WJU3
names: Similarity
messages: Belongs to the UPF0253 family.

2546350:E1B03 RS24945
gene id: 2546350:E1B03_RS24945
uniprot id: A0A4P6WU30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein B family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

2546350:E1B03 RS21450
gene id: 2546350:E1B03_RS21450
uniprot id: A0A4V1AAM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

2546350:E1B03 RS18905
gene id: 2546350:E1B03_RS18905
uniprot id: A0A4V1AAH7
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS09360
gene id: 2546350:E1B03_RS09360
uniprot id: A0A4P6WKH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2546350:E1B03 RS08295
gene id: 2546350:E1B03_RS08295
uniprot id: A0A4P6WH57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TatA/E family. TatE subfamily.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA.

2546350:E1B03 RS24420
gene id: 2546350:E1B03_RS24420
uniprot id: A0A4P6WQ52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

2546350:E1B03 RS25515
gene id: 2546350:E1B03_RS25515
uniprot id: A0A4P6WR04
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

2546350:E1B03 RS19740
gene id: 2546350:E1B03_RS19740
uniprot id: A0A4P6WM60
names: Similarity
messages: Belongs to the P(II) protein family.

2546350:E1B03 RS05975
gene id: 2546350:E1B03_RS05975
uniprot id: A0A4P6WH33
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EcpA/MatB fimbrillin family.
messages: Fimbrium
messages: Self-associates. Forms filaments. Interacts with EcpD.

2546350:E1B03 RS23075
gene id: 2546350:E1B03_RS23075
uniprot id: A0A4P6WT34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
messages: Cell inner membrane
messages: Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system).
messages: Membrane

2546350:E1B03 RS21190
gene id: 2546350:E1B03_RS21190
uniprot id: A0A4P6WSC3
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2546350:E1B03 RS19815
gene id: 2546350:E1B03_RS19815
uniprot id: A0A4P6WQT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

2546350:E1B03 RS23410
gene id: 2546350:E1B03_RS23410
uniprot id: A0A4P6WT92
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

2546350:E1B03 RS05120
gene id: 2546350:E1B03_RS05120
uniprot id: A0A4P6WLF4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

2546350:E1B03 RS19605
gene id: 2546350:E1B03_RS19605
uniprot id: A0A4P6WRN8
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

2546350:E1B03 RS10840
gene id: 2546350:E1B03_RS10840
uniprot id: A0A4P6WME7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2546350:E1B03 RS25480
gene id: 2546350:E1B03_RS25480
uniprot id: A0A4P6WR05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
messages: Cell membrane

2546350:E1B03 RS14780
gene id: 2546350:E1B03_RS14780
uniprot id: A0A4V1AAA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

2546350:E1B03 RS00970
gene id: 2546350:E1B03_RS00970
uniprot id: A0A4P6WJ49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

2546350:E1B03 RS05230
gene id: 2546350:E1B03_RS05230
uniprot id: A0A4P6WI89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

2546350:E1B03 RS22265
gene id: 2546350:E1B03_RS22265
uniprot id: A0A4P6WPK3
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family. HybF subfamily.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

2546350:E1B03 RS07270
gene id: 2546350:E1B03_RS07270
uniprot id: A0A4P6WMR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2546350:E1B03 RS24080
gene id: 2546350:E1B03_RS24080
uniprot id: A0A4P6WVZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2546350:E1B03 RS05500
gene id: 2546350:E1B03_RS05500
uniprot id: A0A4P6WIZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

2546350:E1B03 RS04435
gene id: 2546350:E1B03_RS04435
uniprot id: A0A4P6WM12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

2546350:E1B03 RS25500
gene id: 2546350:E1B03_RS25500
uniprot id: A0A4P6WWT8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

2546350:E1B03 RS02020
gene id: 2546350:E1B03_RS02020
uniprot id: A0A4P6WF31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

2546350:E1B03 RS03230
gene id: 2546350:E1B03_RS03230
uniprot id: A0A4P6WLF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

2546350:E1B03 RS22295
gene id: 2546350:E1B03_RS22295
uniprot id: A0A4P6WRT5
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

2546350:E1B03 RS16635
gene id: 2546350:E1B03_RS16635
uniprot id: A0A4P6WLN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

2546350:E1B03 RS21855
gene id: 2546350:E1B03_RS21855
uniprot id: A0A4P6WRL8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2546350:E1B03 RS17545
gene id: 2546350:E1B03_RS17545
uniprot id: A0A4P6WMG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0387 family.
messages: Cell membrane

2546350:E1B03 RS08385
gene id: 2546350:E1B03_RS08385
uniprot id: A0A4P6WIE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS17920
gene id: 2546350:E1B03_RS17920
uniprot id: A0A4P6WLA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

2546350:E1B03 RS16970
gene id: 2546350:E1B03_RS16970
uniprot id: A0A4P6WKT9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2546350:E1B03 RS06750
gene id: 2546350:E1B03_RS06750
uniprot id: A0A4P6WJ25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

2546350:E1B03 RS22480
gene id: 2546350:E1B03_RS22480
uniprot id: A0A4V1AAP3
names: Similarity
messages: Belongs to the UPF0441 family.

2546350:E1B03 RS00530
gene id: 2546350:E1B03_RS00530
uniprot id: A0A4P6WK37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M23B family.
messages: Membrane

2546350:E1B03 RS08630
gene id: 2546350:E1B03_RS08630
uniprot id: A0A4P6WTW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Provides significant protection from radiation damage and may be involved in the degradation of radiation-damaged nucleotides.
messages: Toroid-shaped homohexamer. In the hexamer, 3 dimers assemble to form a ring-like structure surrounding a central hole.

2546350:E1B03 RS05905
gene id: 2546350:E1B03_RS05905
uniprot id: A0A4V1A9T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

2546350:E1B03 RS17755
gene id: 2546350:E1B03_RS17755
uniprot id: A0A4P6WMK0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

2546350:E1B03 RS19545
gene id: 2546350:E1B03_RS19545
uniprot id: A0A4V1AAI9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

2546350:E1B03 RS23320
gene id: 2546350:E1B03_RS23320
uniprot id: A0A4P6WQ32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

2546350:E1B03 RS22365
gene id: 2546350:E1B03_RS22365
uniprot id: A0A4P6WPM4
names: Subunit
messages: Monomer.

2546350:E1B03 RS03050
gene id: 2546350:E1B03_RS03050
uniprot id: A0A4V1A9N4
names: Similarity
messages: Belongs to the YjdM family.

2546350:E1B03 RS02940
gene id: 2546350:E1B03_RS02940
uniprot id: A0A4P6WEP5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS02100
gene id: 2546350:E1B03_RS02100
uniprot id: A0A4P6WGU1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Does not bind DNA by a helix-turn-helix motif.
messages: Homodimer.
messages: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.

2546350:E1B03 RS00600
gene id: 2546350:E1B03_RS00600
uniprot id: A0A4P6WEG6
names: Similarity
messages: Belongs to the CcdB toxin family.

2546350:E1B03 RS10400
gene id: 2546350:E1B03_RS10400
uniprot id: A0A4P6WJE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0312 family. Type 1 subfamily.
messages: Periplasm

2546350:E1B03 RS18020
gene id: 2546350:E1B03_RS18020
uniprot id: A0A4P6WMP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapF family.
messages: Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

2546350:E1B03 RS05195
gene id: 2546350:E1B03_RS05195
uniprot id: A0A4P6WIV0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

2546350:E1B03 RS14795
gene id: 2546350:E1B03_RS14795
uniprot id: A0A4P6WNG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

2546350:E1B03 RS20030
gene id: 2546350:E1B03_RS20030
uniprot id: A0A4P6WUA3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

2546350:E1B03 RS13400
gene id: 2546350:E1B03_RS13400
uniprot id: A0A4P6WJB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

2546350:E1B03 RS18130
gene id: 2546350:E1B03_RS18130
uniprot id: A0A4P6WTC8
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

2546350:E1B03 RS18400
gene id: 2546350:E1B03_RS18400
uniprot id: A0A4V1AAG8
names: Similarity
messages: Belongs to the UPF0304 family.

2546350:E1B03 RS00960
gene id: 2546350:E1B03_RS00960
uniprot id: A0A4P6WDT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

2546350:E1B03 RS19265
gene id: 2546350:E1B03_RS19265
uniprot id: A0A4P6WQM3
names: Function
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.

2546350:E1B03 RS03435
gene id: 2546350:E1B03_RS03435
uniprot id: A0A4P6WIV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

2546350:E1B03 RS16910
gene id: 2546350:E1B03_RS16910
uniprot id: A0A4P6WM77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

2546350:E1B03 RS03140
gene id: 2546350:E1B03_RS03140
uniprot id: A0A4P6WIR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

2546350:E1B03 RS08300
gene id: 2546350:E1B03_RS08300
uniprot id: A0A4V1A9Y2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

2546350:E1B03 RS01950
gene id: 2546350:E1B03_RS01950
uniprot id: A0A4P6WGR1
names: Subcellular Location Annotation
messages: Cell inner membrane

2546350:E1B03 RS16145
gene id: 2546350:E1B03_RS16145
uniprot id: A0A4P6WP56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

2546350:E1B03 RS04460
gene id: 2546350:E1B03_RS04460
uniprot id: A0A4P6WHV8
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

2546350:E1B03 RS06655
gene id: 2546350:E1B03_RS06655
uniprot id: A0A4P6WHE0
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

2546350:E1B03 RS24545
gene id: 2546350:E1B03_RS24545
uniprot id: A0A4P6WPB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

2546350:E1B03 RS03095
gene id: 2546350:E1B03_RS03095
uniprot id: A0A4P6WLD9
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS04960
gene id: 2546350:E1B03_RS04960
uniprot id: A0A4V1A9R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

2546350:E1B03 RS18460
gene id: 2546350:E1B03_RS18460
uniprot id: A0A4P6WR34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS21925
gene id: 2546350:E1B03_RS21925
uniprot id: A0A4P6WRU8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

2546350:E1B03 RS24995
gene id: 2546350:E1B03_RS24995
uniprot id: A0A4P6WT74
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

2546350:E1B03 RS05715
gene id: 2546350:E1B03_RS05715
uniprot id: A0A4P6WK69
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

2546350:E1B03 RS00445
gene id: 2546350:E1B03_RS00445
uniprot id: A0A4P6WHZ3
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

2546350:E1B03 RS00315
gene id: 2546350:E1B03_RS00315
uniprot id: A0A4P6WDF9
names: Function
names: Similarity
messages: Anion-transporting ATPase.
messages: Belongs to the arsA ATPase family.

2546350:E1B03 RS04950
gene id: 2546350:E1B03_RS04950
uniprot id: A0A4P6WM99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

2546350:E1B03 RS25405
gene id: 2546350:E1B03_RS25405
uniprot id: A0A4P6WTF3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2546350:E1B03 RS11475
gene id: 2546350:E1B03_RS11475
uniprot id: A0A4P6WLW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2546350:E1B03 RS17585
gene id: 2546350:E1B03_RS17585
uniprot id: A0A4P6WQK2
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS16715
gene id: 2546350:E1B03_RS16715
uniprot id: A0A4V1AAD6
names: Function
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.

2546350:E1B03 RS14820
gene id: 2546350:E1B03_RS14820
uniprot id: A0A4P6WRR5
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

2546350:E1B03 RS08340
gene id: 2546350:E1B03_RS08340
uniprot id: A0A4P6WNU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

2546350:E1B03 RS23535
gene id: 2546350:E1B03_RS23535
uniprot id: A0A4P6WSM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RapZ-like family. RapZ subfamily.
messages: Homotrimer.
messages: Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.

2546350:E1B03 RS02225
gene id: 2546350:E1B03_RS02225
uniprot id: A0A4P6WIB2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

2546350:E1B03 RS15780
gene id: 2546350:E1B03_RS15780
uniprot id: A0A4P6WNY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably functions as a manganese efflux pump.

2546350:E1B03 RS12640
gene id: 2546350:E1B03_RS12640
uniprot id: A0A4P6WQR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Proton-dependent permease that transports di- and tripeptides.

2546350:E1B03 RS04910
gene id: 2546350:E1B03_RS04910
uniprot id: A0A4P6WLB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

2546350:E1B03 RS23820
gene id: 2546350:E1B03_RS23820
uniprot id: A0A4P6WSS3
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

2546350:E1B03 RS06930
gene id: 2546350:E1B03_RS06930
uniprot id: A0A4P6WHL0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

2546350:E1B03 RS08265
gene id: 2546350:E1B03_RS08265
uniprot id: A0A4P6WJY6
names: Subcellular Location Annotation
messages: Cytoplasm

2546350:E1B03 RS01170
gene id: 2546350:E1B03_RS01170
uniprot id: A0A4P6WJ92
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS07170
gene id: 2546350:E1B03_RS07170
uniprot id: A0A4P6WKU1
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS04625
gene id: 2546350:E1B03_RS04625
uniprot id: A0A4P6WGG7
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

2546350:E1B03 RS16225
gene id: 2546350:E1B03_RS16225
uniprot id: A0A4P6WPV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

2546350:E1B03 RS01085
gene id: 2546350:E1B03_RS01085
uniprot id: A0A4P6WEU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2546350:E1B03 RS03745
gene id: 2546350:E1B03_RS03745
uniprot id: A0A4P6WJF3
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

2546350:E1B03 RS07215
gene id: 2546350:E1B03_RS07215
uniprot id: A0A4P6WMQ2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

2546350:E1B03 RS21055
gene id: 2546350:E1B03_RS21055
uniprot id: A0A4P6WRF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2546350:E1B03 RS04760
gene id: 2546350:E1B03_RS04760
uniprot id: A0A4P6WL89
names: Function
names: Similarity
messages: Belongs to the bacterial-type ferredoxin family. FixX subfamily.
messages: Could be a 3Fe-4S cluster-containing protein.

2546350:E1B03 RS18355
gene id: 2546350:E1B03_RS18355
uniprot id: A0A4P6WR14
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

2546350:E1B03 RS24405
gene id: 2546350:E1B03_RS24405
uniprot id: A0A4P6WW60
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

2546350:E1B03 RS13500
gene id: 2546350:E1B03_RS13500
uniprot id: A0A4P6WKN7
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

2546350:E1B03 RS24150
gene id: 2546350:E1B03_RS24150
uniprot id: A0A4P6WTP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2546350:E1B03 RS03315
gene id: 2546350:E1B03_RS03315
uniprot id: A0A4P6WFV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
messages: Homodimer.
messages: With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.

2546350:E1B03 RS24750
gene id: 2546350:E1B03_RS24750
uniprot id: A0A4P6WWE4
names: Similarity
messages: Belongs to the leucine-binding protein family.

2546350:E1B03 RS03545
gene id: 2546350:E1B03_RS03545
uniprot id: A0A4P6WI45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

2546350:E1B03 RS24075
gene id: 2546350:E1B03_RS24075
uniprot id: A0A4V1AAS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2546350:E1B03 RS21605
gene id: 2546350:E1B03_RS21605
uniprot id: A0A4P6WPA1
names: Similarity
messages: Belongs to the FrmR/RcnR family.

2546350:E1B03 RS10300
gene id: 2546350:E1B03_RS10300
uniprot id: A0A4V1AA19
names: Function
names: Similarity
messages: Belongs to the CsgG family.
messages: May be involved in the biogenesis of curli organelles.

2546350:E1B03 RS15690
gene id: 2546350:E1B03_RS15690
uniprot id: A0A4P6WK98
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family. CntA subfamily.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of an oxygenase subunit and a reductase subunit.
messages: Converts carnitine to trimethylamine and malic semialdehyde.

2546350:E1B03 RS12680
gene id: 2546350:E1B03_RS12680
uniprot id: A0A4P6WMD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2546350:E1B03 RS24145
gene id: 2546350:E1B03_RS24145
uniprot id: A0A4P6WQ07
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2546350:E1B03 RS05825
gene id: 2546350:E1B03_RS05825
uniprot id: A0A4P6WH08
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2546350:E1B03 RS04955
gene id: 2546350:E1B03_RS04955
uniprot id: A0A4P6WFM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2546350:E1B03 RS24120
gene id: 2546350:E1B03_RS24120
uniprot id: A0A4P6WP22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2546350:E1B03 RS12555
gene id: 2546350:E1B03_RS12555
uniprot id: A0A4P6WQG7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

2546350:E1B03 RS04665
gene id: 2546350:E1B03_RS04665
uniprot id: A0A4P6WJR8
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS05345
gene id: 2546350:E1B03_RS05345
uniprot id: A0A4P6WJS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

2546350:E1B03 RS09150
gene id: 2546350:E1B03_RS09150
uniprot id: A0A4P6WNX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS05880
gene id: 2546350:E1B03_RS05880
uniprot id: A0A4P6WK14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

2546350:E1B03 RS02785
gene id: 2546350:E1B03_RS02785
uniprot id: A0A4V1A9M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

2546350:E1B03 RS02350
gene id: 2546350:E1B03_RS02350
uniprot id: A0A4P6WJY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2546350:E1B03 RS16105
gene id: 2546350:E1B03_RS16105
uniprot id: A0A4P6WS96
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

2546350:E1B03 RS20625
gene id: 2546350:E1B03_RS20625
uniprot id: A0A4P6WNG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

2546350:E1B03 RS17290
gene id: 2546350:E1B03_RS17290
uniprot id: A0A4P6WSN4
names: Similarity
messages: Belongs to the UPF0145 family.

2546350:E1B03 RS11690
gene id: 2546350:E1B03_RS11690
uniprot id: A0A4P6WLR1
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

2546350:E1B03 RS01905
gene id: 2546350:E1B03_RS01905
uniprot id: A0A4P6WHA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
messages: Cell membrane
messages: Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system).

2546350:E1B03 RS19065
gene id: 2546350:E1B03_RS19065
uniprot id: A0A4P6WQI9
names: Subcellular Location Annotation
messages: Cytoplasm

2546350:E1B03 RS06925
gene id: 2546350:E1B03_RS06925
uniprot id: A0A4P6WJN1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2546350:E1B03 RS08310
gene id: 2546350:E1B03_RS08310
uniprot id: A0A4P6WLD3
names: Similarity
messages: Belongs to the UPF0250 family.

2546350:E1B03 RS01150
gene id: 2546350:E1B03_RS01150
uniprot id: A0A4P6WER3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS04920
gene id: 2546350:E1B03_RS04920
uniprot id: A0A4P6WRD2
names: Function
messages: Involved in control of the biosynthesis of leucine.

2546350:E1B03 RS05690
gene id: 2546350:E1B03_RS05690
uniprot id: A0A4P6WGT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

2546350:E1B03 RS11520
gene id: 2546350:E1B03_RS11520
uniprot id: A0A4P6WJF2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2546350:E1B03 RS23310
gene id: 2546350:E1B03_RS23310
uniprot id: A0A4P6WTB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2546350:E1B03 RS02335
gene id: 2546350:E1B03_RS02335
uniprot id: A0A4P6WKY7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2546350:E1B03 RS18325
gene id: 2546350:E1B03_RS18325
uniprot id: A0A4P6WQ77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2546350:E1B03 RS16445
gene id: 2546350:E1B03_RS16445
uniprot id: A0A4P6WSA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Flagellar protein that affects chemotactic events.
messages: Membrane

2546350:E1B03 RS17955
gene id: 2546350:E1B03_RS17955
uniprot id: A0A4P6WM93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

2546350:E1B03 RS20580
gene id: 2546350:E1B03_RS20580
uniprot id: A0A4V1AAK8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

2546350:E1B03 RS22585
gene id: 2546350:E1B03_RS22585
uniprot id: A0A4P6WND3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

2546350:E1B03 RS08915
gene id: 2546350:E1B03_RS08915
uniprot id: A0A4P6WKK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

2546350:E1B03 RS24015
gene id: 2546350:E1B03_RS24015
uniprot id: A0A4P6WW20
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2546350:E1B03 RS19730
gene id: 2546350:E1B03_RS19730
uniprot id: A0A4P6WNI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

2546350:E1B03 RS09905
gene id: 2546350:E1B03_RS09905
uniprot id: A0A4P6WPK5
names: Subcellular Location Annotation
messages: Cell inner membrane

2546350:E1B03 RS15670
gene id: 2546350:E1B03_RS15670
uniprot id: A0A4P6WPP2
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

2546350:E1B03 RS21755
gene id: 2546350:E1B03_RS21755
uniprot id: A0A4P6WRS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

2546350:E1B03 RS07145
gene id: 2546350:E1B03_RS07145
uniprot id: A0A4P6WHP5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2546350:E1B03 RS10825
gene id: 2546350:E1B03_RS10825
uniprot id: A0A4V1AA28
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family. NagK subfamily.
messages: Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.

2546350:E1B03 RS04160
gene id: 2546350:E1B03_RS04160
uniprot id: A0A4P6WLW9
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS18370
gene id: 2546350:E1B03_RS18370
uniprot id: A0A4P6WQX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2546350:E1B03 RS01725
gene id: 2546350:E1B03_RS01725
uniprot id: A0A4P6WJH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

2546350:E1B03 RS15310
gene id: 2546350:E1B03_RS15310
uniprot id: A0A4P6WK47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain.

2546350:E1B03 RS25935
gene id: 2546350:E1B03_RS25935
uniprot id: A0A4V1AAV7
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

2546350:E1B03 RS09465
gene id: 2546350:E1B03_RS09465
uniprot id: A0A4P6WKJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
messages: Cell membrane

2546350:E1B03 RS09995
gene id: 2546350:E1B03_RS09995
uniprot id: A0A4P6WLB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

2546350:E1B03 RS19170
gene id: 2546350:E1B03_RS19170
uniprot id: A0A4P6WN79
names: Similarity
messages: Belongs to the acetyltransferase family. YpeA subfamily.

2546350:E1B03 RS05725
gene id: 2546350:E1B03_RS05725
uniprot id: A0A4P6WGY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2546350:E1B03 RS09655
gene id: 2546350:E1B03_RS09655
uniprot id: A0A4P6WPG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

2546350:E1B03 RS24525
gene id: 2546350:E1B03_RS24525
uniprot id: A0A4P6WTV8
names: Function
names: Similarity
messages: Belongs to the FeoC family.
messages: May function as a transcriptional regulator that controls feoABC expression.

2546350:E1B03 RS26075
gene id: 2546350:E1B03_RS26075
uniprot id: A0A4P6WX03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations.

2546350:E1B03 RS02345
gene id: 2546350:E1B03_RS02345
uniprot id: A0A4V1A9M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.
messages: Protein L10 is also a translational repressor protein. It controls the translation of the rplJL-rpoBC operon by binding to its mRNA.

2546350:E1B03 RS19800
gene id: 2546350:E1B03_RS19800
uniprot id: A0A4P6WTV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

2546350:E1B03 RS13780
gene id: 2546350:E1B03_RS13780
uniprot id: A0A4P6WR13
names: Similarity
messages: Belongs to the FrmR/RcnR family.

2546350:E1B03 RS18530
gene id: 2546350:E1B03_RS18530
uniprot id: A0A4P6WMG9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2546350:E1B03 RS19535
gene id: 2546350:E1B03_RS19535
uniprot id: A0A4P6WU16
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

2546350:E1B03 RS24115
gene id: 2546350:E1B03_RS24115
uniprot id: A0A4P6WW38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2546350:E1B03 RS08690
gene id: 2546350:E1B03_RS08690
uniprot id: A0A4P6WP02
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

2546350:E1B03 RS16095
gene id: 2546350:E1B03_RS16095
uniprot id: A0A4P6WRI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

2546350:E1B03 RS14165
gene id: 2546350:E1B03_RS14165
uniprot id: A0A4P6WKN1
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS24040
gene id: 2546350:E1B03_RS24040
uniprot id: A0A4P6WSL0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2546350:E1B03 RS03205
gene id: 2546350:E1B03_RS03205
uniprot id: A0A4P6WHC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

2546350:E1B03 RS08870
gene id: 2546350:E1B03_RS08870
uniprot id: A0A4P6WLL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2546350:E1B03 RS17230
gene id: 2546350:E1B03_RS17230
uniprot id: A0A4P6WKY6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2546350:E1B03 RS06845
gene id: 2546350:E1B03_RS06845
uniprot id: A0A4P6WMI6
names: Similarity
messages: Belongs to the UPF0234 family.

2546350:E1B03 RS13760
gene id: 2546350:E1B03_RS13760
uniprot id: A0A4P6WR96
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2546350:E1B03 RS23685
gene id: 2546350:E1B03_RS23685
uniprot id: A0A4P6WTD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2546350:E1B03 RS05805
gene id: 2546350:E1B03_RS05805
uniprot id: A0A4V1A9T5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2546350:E1B03 RS11590
gene id: 2546350:E1B03_RS11590
uniprot id: A0A4P6WJG4
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

2546350:E1B03 RS22055
gene id: 2546350:E1B03_RS22055
uniprot id: A0A4V1AAN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
messages: Monomer.

2546350:E1B03 RS09915
gene id: 2546350:E1B03_RS09915
uniprot id: A0A4V1AA12
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

2546350:E1B03 RS24800
gene id: 2546350:E1B03_RS24800
uniprot id: A0A4P6WQP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

2546350:E1B03 RS19405
gene id: 2546350:E1B03_RS19405
uniprot id: A0A4P6WRJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

2546350:E1B03 RS08935
gene id: 2546350:E1B03_RS08935
uniprot id: A0A4V1A9Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

2546350:E1B03 RS22995
gene id: 2546350:E1B03_RS22995
uniprot id: A0A4P6WVL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS14335
gene id: 2546350:E1B03_RS14335
uniprot id: A0A4P6WRJ1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

2546350:E1B03 RS07075
gene id: 2546350:E1B03_RS07075
uniprot id: A0A4P6WHK1
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

2546350:E1B03 RS23995
gene id: 2546350:E1B03_RS23995
uniprot id: A0A4P6WPY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

2546350:E1B03 RS01610
gene id: 2546350:E1B03_RS01610
uniprot id: A0A4P6WF27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

2546350:E1B03 RS13975
gene id: 2546350:E1B03_RS13975
uniprot id: A0A4P6WKV3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

2546350:E1B03 RS09250
gene id: 2546350:E1B03_RS09250
uniprot id: A0A4P6WNZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2546350:E1B03 RS24180
gene id: 2546350:E1B03_RS24180
uniprot id: A0A4P6WW21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2546350:E1B03 RS13515
gene id: 2546350:E1B03_RS13515
uniprot id: A0A4V1AA77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS14930
gene id: 2546350:E1B03_RS14930
uniprot id: A0A4P6WNF0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

2546350:E1B03 RS06675
gene id: 2546350:E1B03_RS06675
uniprot id: A0A4P6WN26
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS11905
gene id: 2546350:E1B03_RS11905
uniprot id: A0A4P6WLV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

2546350:E1B03 RS22280
gene id: 2546350:E1B03_RS22280
uniprot id: A0A4V1AAN9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

2546350:E1B03 RS22565
gene id: 2546350:E1B03_RS22565
uniprot id: A0A4P6WSZ5
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS05490
gene id: 2546350:E1B03_RS05490
uniprot id: A0A4P6WGV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2546350:E1B03 RS02615
gene id: 2546350:E1B03_RS02615
uniprot id: A0A4P6WL43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

2546350:E1B03 RS04430
gene id: 2546350:E1B03_RS04430
uniprot id: A0A4P6WG88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

2546350:E1B03 RS01820
gene id: 2546350:E1B03_RS01820
uniprot id: A0A4P6WE63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

2546350:E1B03 RS00955
gene id: 2546350:E1B03_RS00955
uniprot id: A0A4P6WKC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

2546350:E1B03 RS16010
gene id: 2546350:E1B03_RS16010
uniprot id: A0A4V1AAC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

2546350:E1B03 RS23425
gene id: 2546350:E1B03_RS23425
uniprot id: A0A4P6WPP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

2546350:E1B03 RS17320
gene id: 2546350:E1B03_RS17320
uniprot id: A0A4P6WMD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

2546350:E1B03 RS25750
gene id: 2546350:E1B03_RS25750
uniprot id: A0A4P6WR49
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2546350:E1B03 RS19695
gene id: 2546350:E1B03_RS19695
uniprot id: A0A4V1AAJ2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2546350:E1B03 RS24085
gene id: 2546350:E1B03_RS24085
uniprot id: A0A4P6WTJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

2546350:E1B03 RS01075
gene id: 2546350:E1B03_RS01075
uniprot id: A0A4P6WIA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

2546350:E1B03 RS01010
gene id: 2546350:E1B03_RS01010
uniprot id: A0A4P6WDU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

2546350:E1B03 RS15830
gene id: 2546350:E1B03_RS15830
uniprot id: A0A4P6WNZ5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

2546350:E1B03 RS04575
gene id: 2546350:E1B03_RS04575
uniprot id: A0A4P6WJE2
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS10520
gene id: 2546350:E1B03_RS10520
uniprot id: A0A4P6WI51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

2546350:E1B03 RS08210
gene id: 2546350:E1B03_RS08210
uniprot id: A0A4P6WLB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rnk family.
messages: Interacts with the RNA polymerase.
messages: May act as an anti-Gre factor.

2546350:E1B03 RS18340
gene id: 2546350:E1B03_RS18340
uniprot id: A0A4P6WLH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

2546350:E1B03 RS01755
gene id: 2546350:E1B03_RS01755
uniprot id: A0A4P6WEZ4
names: Subcellular Location Annotation
messages: Membrane

2546350:E1B03 RS16085
gene id: 2546350:E1B03_RS16085
uniprot id: A0A4P6WPX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

2546350:E1B03 RS04565
gene id: 2546350:E1B03_RS04565
uniprot id: A0A4P6WHX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

2546350:E1B03 RS02755
gene id: 2546350:E1B03_RS02755
uniprot id: A0A4P6WFK9
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

2546350:E1B03 RS16790
gene id: 2546350:E1B03_RS16790
uniprot id: A0A4P6WQ83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the bacterial microcompartments protein family.
messages: The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.

2546350:E1B03 RS05545
gene id: 2546350:E1B03_RS05545
uniprot id: A0A4V1A9T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0294 family.
messages: Cytoplasm

2546350:E1B03 RS01745
gene id: 2546350:E1B03_RS01745
uniprot id: A0A4P6WI33
names: Function
names: Similarity
messages: Belongs to the aldolase LacD family.
messages: Cleaves 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP) to form dihydroxyacetone phosphate (DHAP) and 3-sulfolactaldehyde (SLA).

2546350:E1B03 RS17970
gene id: 2546350:E1B03_RS17970
uniprot id: A0A4P6WMN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

2546350:E1B03 RS06630
gene id: 2546350:E1B03_RS06630
uniprot id: A0A4V1A9V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

2546350:E1B03 RS12195
gene id: 2546350:E1B03_RS12195
uniprot id: A0A4P6WIT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

2546350:E1B03 RS23135
gene id: 2546350:E1B03_RS23135
uniprot id: A0A4P6WT45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2546350:E1B03 RS21995
gene id: 2546350:E1B03_RS21995
uniprot id: A0A4P6WV69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

2546350:E1B03 RS13645
gene id: 2546350:E1B03_RS13645
uniprot id: A0A4P6WMU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2546350:E1B03 RS02720
gene id: 2546350:E1B03_RS02720
uniprot id: A0A4P6WL62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. DnaB subfamily.
messages: Homohexamer.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

2546350:E1B03 RS18665
gene id: 2546350:E1B03_RS18665
uniprot id: A0A4P6WLM9
names: Similarity
messages: Belongs to the UPF0381 family.

2546350:E1B03 RS24170
gene id: 2546350:E1B03_RS24170
uniprot id: A0A4P6WP32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2546350:E1B03 RS14330
gene id: 2546350:E1B03_RS14330
uniprot id: A0A4P6WL25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

2546350:E1B03 RS18485
gene id: 2546350:E1B03_RS18485
uniprot id: A0A4P6WMX6
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2546350:E1B03 RS19205
gene id: 2546350:E1B03_RS19205
uniprot id: A0A4P6WMS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

2546350:E1B03 RS16665
gene id: 2546350:E1B03_RS16665
uniprot id: A0A4V1AAD5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

2546350:E1B03 RS11340
gene id: 2546350:E1B03_RS11340
uniprot id: A0A4P6WPY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

2546350:E1B03 RS05940
gene id: 2546350:E1B03_RS05940
uniprot id: A0A4P6WGY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

2546350:E1B03 RS14765
gene id: 2546350:E1B03_RS14765
uniprot id: A0A4P6WL94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2546350:E1B03 RS01545
gene id: 2546350:E1B03_RS01545
uniprot id: A0A4P6WJF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2546350:E1B03 RS19805
gene id: 2546350:E1B03_RS19805
uniprot id: A0A4P6WRT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

2546350:E1B03 RS21030
gene id: 2546350:E1B03_RS21030
uniprot id: A0A4P6WUF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

2546350:E1B03 RS21110
gene id: 2546350:E1B03_RS21110
uniprot id: A0A4P6WP30
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.