254:EG358 RS02990
gene id: 254:EG358_RS02990
uniprot id: A0A381F748
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS05505
gene id: 254:EG358_RS05505
uniprot id: A0A381F8T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

254:EG358 RS17750
gene id: 254:EG358_RS17750
uniprot id: A0A381JQL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

254:EG358 RS10035
gene id: 254:EG358_RS10035
uniprot id: A0A381FDI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

254:EG358 RS04445
gene id: 254:EG358_RS04445
uniprot id: A0A381F810
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

254:EG358 RS09290
gene id: 254:EG358_RS09290
uniprot id: A0A381FCZ6
names: Caution
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

254:EG358 RS10695
gene id: 254:EG358_RS10695
uniprot id: A0A381FED9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

254:EG358 RS12730
gene id: 254:EG358_RS12730
uniprot id: A0A381FGD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

254:EG358 RS12570
gene id: 254:EG358_RS12570
uniprot id: A0A381FA96
names: Similarity
messages: Belongs to the glutathione peroxidase family.

254:EG358 RS00075
gene id: 254:EG358_RS00075
uniprot id: A0A381F5G7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

254:EG358 RS00105
gene id: 254:EG358_RS00105
uniprot id: A0A381F6S4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

254:EG358 RS02080
gene id: 254:EG358_RS02080
uniprot id: A0A381FKU5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

254:EG358 RS02810
gene id: 254:EG358_RS02810
uniprot id: A0A381F6W7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

254:EG358 RS01465
gene id: 254:EG358_RS01465
uniprot id: A0A381F689
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

254:EG358 RS18760
gene id: 254:EG358_RS18760
uniprot id: A0A381JSX7
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS04625
gene id: 254:EG358_RS04625
uniprot id: A0A381F816
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

254:EG358 RS03475
gene id: 254:EG358_RS03475
uniprot id: A0A381FK06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

254:EG358 RS08910
gene id: 254:EG358_RS08910
uniprot id: A0A381FC90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

254:EG358 RS02240
gene id: 254:EG358_RS02240
uniprot id: A0A381F6Z6
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

254:EG358 RS04225
gene id: 254:EG358_RS04225
uniprot id: A0A381F7S5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

254:EG358 RS03670
gene id: 254:EG358_RS03670
uniprot id: A0A381F7T3
names: Similarity
messages: Belongs to the RecJ family.

254:EG358 RS04090
gene id: 254:EG358_RS04090
uniprot id: A0A381F941
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

254:EG358 RS13950
gene id: 254:EG358_RS13950
uniprot id: A0A381F437
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS07825
gene id: 254:EG358_RS07825
uniprot id: A0A381FB97
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

254:EG358 RS05150
gene id: 254:EG358_RS05150
uniprot id: A0A381F8J1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

254:EG358 RS06265
gene id: 254:EG358_RS06265
uniprot id: A0A381F9D7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

254:EG358 RS10675
gene id: 254:EG358_RS10675
uniprot id: A0A381FEC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

254:EG358 RS06835
gene id: 254:EG358_RS06835
uniprot id: A0A381F9X8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

254:EG358 RS17265
gene id: 254:EG358_RS17265
uniprot id: A0A381JQN5
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS02750
gene id: 254:EG358_RS02750
uniprot id: A0A381F763
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS01680
gene id: 254:EG358_RS01680
uniprot id: A0A381F6B8
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

254:EG358 RS14310
gene id: 254:EG358_RS14310
uniprot id: A0A381F441
names: Similarity
messages: Belongs to the TrpF family.

254:EG358 RS03590
gene id: 254:EG358_RS03590
uniprot id: A0A381F8T9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

254:EG358 RS11915
gene id: 254:EG358_RS11915
uniprot id: A0A381FFL9
names: Similarity
messages: Belongs to the peptidase C40 family.

254:EG358 RS01570
gene id: 254:EG358_RS01570
uniprot id: A0A381F7I3
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

254:EG358 RS16515
gene id: 254:EG358_RS16515
uniprot id: A0A381FPC7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

254:EG358 RS13090
gene id: 254:EG358_RS13090
uniprot id: A0A381FGP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

254:EG358 RS14485
gene id: 254:EG358_RS14485
uniprot id: A0A381F4F3
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

254:EG358 RS06385
gene id: 254:EG358_RS06385
uniprot id: A0A381F9I8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS10120
gene id: 254:EG358_RS10120
uniprot id: A0A381FEU0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

254:EG358 RS03795
gene id: 254:EG358_RS03795
uniprot id: A0A381F7S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

254:EG358 RS05020
gene id: 254:EG358_RS05020
uniprot id: A0A381F8E8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

254:EG358 RS03225
gene id: 254:EG358_RS03225
uniprot id: A0A381F7F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

254:EG358 RS05920
gene id: 254:EG358_RS05920
uniprot id: A0A381F9E7
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

254:EG358 RS16355
gene id: 254:EG358_RS16355
uniprot id: A0A381FP96
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

254:EG358 RS09625
gene id: 254:EG358_RS09625
uniprot id: A0A381FD65
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS04700
gene id: 254:EG358_RS04700
uniprot id: A0A381F8E7
names: Similarity
messages: Belongs to the UxaA family.

254:EG358 RS07340
gene id: 254:EG358_RS07340
uniprot id: A0A381FAT0
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

254:EG358 RS01740
gene id: 254:EG358_RS01740
uniprot id: A0A381FL47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

254:EG358 RS06710
gene id: 254:EG358_RS06710
uniprot id: A0A381FA48
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

254:EG358 RS15050
gene id: 254:EG358_RS15050
uniprot id: A0A381F4J6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS06750
gene id: 254:EG358_RS06750
uniprot id: A0A381FBA3
names: Similarity
messages: Belongs to the Nth/MutY family.

254:EG358 RS18715
gene id: 254:EG358_RS18715
uniprot id: A0A381JSW7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

254:EG358 RS18480
gene id: 254:EG358_RS18480
uniprot id: A0A381JT30
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

254:EG358 RS04500
gene id: 254:EG358_RS04500
uniprot id: A0A381F7X9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

254:EG358 RS19190
gene id: 254:EG358_RS19190
uniprot id: A0A381JR18
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

254:EG358 RS10825
gene id: 254:EG358_RS10825
uniprot id: A0A381FFM6
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS13225
gene id: 254:EG358_RS13225
uniprot id: A0A381FI22
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

254:EG358 RS08995
gene id: 254:EG358_RS08995
uniprot id: A0A381FFV7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

254:EG358 RS00625
gene id: 254:EG358_RS00625
uniprot id: A0A381F625
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

254:EG358 RS09890
gene id: 254:EG358_RS09890
uniprot id: A0A381FFQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

254:EG358 RS02480
gene id: 254:EG358_RS02480
uniprot id: A0A381F824
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

254:EG358 RS11110
gene id: 254:EG358_RS11110
uniprot id: A0A381FEU7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

254:EG358 RS15815
gene id: 254:EG358_RS15815
uniprot id: A0A381FPV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

254:EG358 RS00750
gene id: 254:EG358_RS00750
uniprot id: A0A381F736
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

254:EG358 RS19120
gene id: 254:EG358_RS19120
uniprot id: A0A381JTF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

254:EG358 RS00315
gene id: 254:EG358_RS00315
uniprot id: A0A381F5M4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

254:EG358 RS18895
gene id: 254:EG358_RS18895
uniprot id: A0A3G6PES0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

254:EG358 RS05670
gene id: 254:EG358_RS05670
uniprot id: A0A381F8W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

254:EG358 RS10085
gene id: 254:EG358_RS10085
uniprot id: A0A381FDN4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

254:EG358 RS09080
gene id: 254:EG358_RS09080
uniprot id: A0A381FCS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

254:EG358 RS19500
gene id: 254:EG358_RS19500
uniprot id: A0A381FMK3
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS16275
gene id: 254:EG358_RS16275
uniprot id: A0A381F6J5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

254:EG358 RS18995
gene id: 254:EG358_RS18995
uniprot id: A0A381FMT8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

254:EG358 RS12665
gene id: 254:EG358_RS12665
uniprot id: A0A381FGE8
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS13135
gene id: 254:EG358_RS13135
uniprot id: A0A381F939
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

254:EG358 RS09130
gene id: 254:EG358_RS09130
uniprot id: A0A381FCT9
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS17640
gene id: 254:EG358_RS17640
uniprot id: A0A381JRE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

254:EG358 RS16105
gene id: 254:EG358_RS16105
uniprot id: A0A381F5C3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

254:EG358 RS16535
gene id: 254:EG358_RS16535
uniprot id: A0A381JRF6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

254:EG358 RS17635
gene id: 254:EG358_RS17635
uniprot id: A0A381FND3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

254:EG358 RS09125
gene id: 254:EG358_RS09125
uniprot id: A0A381FCK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

254:EG358 RS04405
gene id: 254:EG358_RS04405
uniprot id: A0A381F7W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

254:EG358 RS17830
gene id: 254:EG358_RS17830
uniprot id: A0A381JSV3
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS11420
gene id: 254:EG358_RS11420
uniprot id: A0A381FFE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

254:EG358 RS01895
gene id: 254:EG358_RS01895
uniprot id: A0A381F6J8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

254:EG358 RS06725
gene id: 254:EG358_RS06725
uniprot id: A0A381FA32
names: Similarity
messages: Belongs to the peptidase M13 family.

254:EG358 RS03140
gene id: 254:EG358_RS03140
uniprot id: A0A381F772
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

254:EG358 RS01045
gene id: 254:EG358_RS01045
uniprot id: A0A381F610
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS14040
gene id: 254:EG358_RS14040
uniprot id: A0A381F3Z0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

254:EG358 RS17340
gene id: 254:EG358_RS17340
uniprot id: A0A381JQ22
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

254:EG358 RS02210
gene id: 254:EG358_RS02210
uniprot id: A0A381F6Z0
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

254:EG358 RS12855
gene id: 254:EG358_RS12855
uniprot id: A0A381FGQ3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS17475
gene id: 254:EG358_RS17475
uniprot id: A0A381JQ39
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS13005
gene id: 254:EG358_RS13005
uniprot id: A0A381FGQ7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

254:EG358 RS03005
gene id: 254:EG358_RS03005
uniprot id: A0A381F707
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

254:EG358 RS05840
gene id: 254:EG358_RS05840
uniprot id: A0A381F917
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS10410
gene id: 254:EG358_RS10410
uniprot id: A0A381FDZ0
names: Similarity
messages: Belongs to the pirin family.

254:EG358 RS02665
gene id: 254:EG358_RS02665
uniprot id: A0A381F6X7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

254:EG358 RS04355
gene id: 254:EG358_RS04355
uniprot id: A0A381F7U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

254:EG358 RS03055
gene id: 254:EG358_RS03055
uniprot id: A0A381F722
names: Similarity
messages: Belongs to the asparagine synthetase family.

254:EG358 RS17940
gene id: 254:EG358_RS17940
uniprot id: A0A381FN18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

254:EG358 RS17550
gene id: 254:EG358_RS17550
uniprot id: A0A381FNQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

254:EG358 RS03585
gene id: 254:EG358_RS03585
uniprot id: A0A381FKX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

254:EG358 RS11855
gene id: 254:EG358_RS11855
uniprot id: A0A381FB82
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

254:EG358 RS08670
gene id: 254:EG358_RS08670
uniprot id: A0A381FC12
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

254:EG358 RS14405
gene id: 254:EG358_RS14405
uniprot id: A0A381F5E5
names: Similarity
messages: Belongs to the SusD family.

254:EG358 RS18930
gene id: 254:EG358_RS18930
uniprot id: A0A381JRI8
names: Similarity
messages: Belongs to the peptidase C40 family.

254:EG358 RS09305
gene id: 254:EG358_RS09305
uniprot id: A0A381FCW7
names: Similarity
messages: Belongs to the OsmC/Ohr family.

254:EG358 RS18450
gene id: 254:EG358_RS18450
uniprot id: A0A381JQN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

254:EG358 RS16220
gene id: 254:EG358_RS16220
uniprot id: A0A381F585
names: Similarity
messages: Belongs to the polysaccharide synthase family.

254:EG358 RS02685
gene id: 254:EG358_RS02685
uniprot id: A0A381F799
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

254:EG358 RS13195
gene id: 254:EG358_RS13195
uniprot id: A0A381FGV6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

254:EG358 RS05930
gene id: 254:EG358_RS05930
uniprot id: A0A381F9B9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

254:EG358 RS13155
gene id: 254:EG358_RS13155
uniprot id: A0A381FHZ5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

254:EG358 RS09020
gene id: 254:EG358_RS09020
uniprot id: A0A381FCJ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

254:EG358 RS17985
gene id: 254:EG358_RS17985
uniprot id: A0A381JQE1
names: Similarity
messages: Belongs to the RelE toxin family.

254:EG358 RS11830
gene id: 254:EG358_RS11830
uniprot id: A0A381FFN7
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS10200
gene id: 254:EG358_RS10200
uniprot id: A0A381FEX3
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

254:EG358 RS13280
gene id: 254:EG358_RS13280
uniprot id: A0A381F8W5
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

254:EG358 RS02410
gene id: 254:EG358_RS02410
uniprot id: A0A381F726
names: Similarity
messages: Belongs to the TPP enzyme family.

254:EG358 RS03220
gene id: 254:EG358_RS03220
uniprot id: A0A381F8K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

254:EG358 RS04100
gene id: 254:EG358_RS04100
uniprot id: A0A381FJI7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

254:EG358 RS04190
gene id: 254:EG358_RS04190
uniprot id: A0A381F812
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

254:EG358 RS02285
gene id: 254:EG358_RS02285
uniprot id: A0A381F6W4
names: Similarity
messages: Belongs to the glutamine synthetase family.

254:EG358 RS11555
gene id: 254:EG358_RS11555
uniprot id: A0A381FGF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

254:EG358 RS13355
gene id: 254:EG358_RS13355
uniprot id: A0A381FH28
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

254:EG358 RS09770
gene id: 254:EG358_RS09770
uniprot id: A0A381FDA3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

254:EG358 RS13935
gene id: 254:EG358_RS13935
uniprot id: A0A381F3V6
names: Similarity
messages: Belongs to the UPF0246 family.

254:EG358 RS18120
gene id: 254:EG358_RS18120
uniprot id: A0A381JQS6
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

254:EG358 RS17645
gene id: 254:EG358_RS17645
uniprot id: A0A381JQ75
names: Similarity
messages: Belongs to the peptidase S49 family.

254:EG358 RS07740
gene id: 254:EG358_RS07740
uniprot id: A0A381FB69
names: Similarity
messages: Belongs to the DEAD box helicase family.

254:EG358 RS07115
gene id: 254:EG358_RS07115
uniprot id: A0A381FAH4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

254:EG358 RS05960
gene id: 254:EG358_RS05960
uniprot id: A0A381F9H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

254:EG358 RS05585
gene id: 254:EG358_RS05585
uniprot id: A0A381F926
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

254:EG358 RS04170
gene id: 254:EG358_RS04170
uniprot id: A0A381F7R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

254:EG358 RS11875
gene id: 254:EG358_RS11875
uniprot id: A0A381FFP5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

254:EG358 RS16480
gene id: 254:EG358_RS16480
uniprot id: A0A381JRG9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

254:EG358 RS03615
gene id: 254:EG358_RS03615
uniprot id: A0A381F7M6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

254:EG358 RS17510
gene id: 254:EG358_RS17510
uniprot id: A0A381JRN3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

254:EG358 RS16180
gene id: 254:EG358_RS16180
uniprot id: A0A381F6H6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

254:EG358 RS03530
gene id: 254:EG358_RS03530
uniprot id: A0A381F7F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

254:EG358 RS03560
gene id: 254:EG358_RS03560
uniprot id: A0A381F7L3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

254:EG358 RS10745
gene id: 254:EG358_RS10745
uniprot id: A0A381FFJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

254:EG358 RS02430
gene id: 254:EG358_RS02430
uniprot id: A0A381F814
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

254:EG358 RS16810
gene id: 254:EG358_RS16810
uniprot id: A0A381JRE5
names: Subcellular Location Annotation
messages: Cytoplasm

254:EG358 RS12745
gene id: 254:EG358_RS12745
uniprot id: A0A381F9P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

254:EG358 RS06450
gene id: 254:EG358_RS06450
uniprot id: A0A381F9M8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS00195
gene id: 254:EG358_RS00195
uniprot id: A0A381F5H7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

254:EG358 RS01115
gene id: 254:EG358_RS01115
uniprot id: A0A381F607
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS09880
gene id: 254:EG358_RS09880
uniprot id: A0A381FDC2
names: Similarity
messages: Belongs to the barstar family.

254:EG358 RS00740
gene id: 254:EG358_RS00740
uniprot id: A0A381FMQ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

254:EG358 RS12245
gene id: 254:EG358_RS12245
uniprot id: A0A381FH33
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

254:EG358 RS17000
gene id: 254:EG358_RS17000
uniprot id: A0A381JSN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

254:EG358 RS15290
gene id: 254:EG358_RS15290
uniprot id: A0A381F4X8
names: Similarity
messages: Belongs to the peptidase S9C family.

254:EG358 RS01145
gene id: 254:EG358_RS01145
uniprot id: A0A381F631
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

254:EG358 RS02915
gene id: 254:EG358_RS02915
uniprot id: A0A381F724
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

254:EG358 RS01460
gene id: 254:EG358_RS01460
uniprot id: A0A381F656
names: Similarity
messages: Belongs to the LacAB/RpiB family.

254:EG358 RS01110
gene id: 254:EG358_RS01110
uniprot id: A0A381F5Y9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS01960
gene id: 254:EG358_RS01960
uniprot id: A0A381F6T1
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

254:EG358 RS02415
gene id: 254:EG358_RS02415
uniprot id: A0A381F6Q0
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS11030
gene id: 254:EG358_RS11030
uniprot id: A0A381FEQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

254:EG358 RS11945
gene id: 254:EG358_RS11945
uniprot id: A0A381FGU2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

254:EG358 RS16050
gene id: 254:EG358_RS16050
uniprot id: A0A381F572
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

254:EG358 RS01560
gene id: 254:EG358_RS01560
uniprot id: A0A381F6A9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

254:EG358 RS14505
gene id: 254:EG358_RS14505
uniprot id: A0A381F5H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

254:EG358 RS05075
gene id: 254:EG358_RS05075
uniprot id: A0A381F8L6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

254:EG358 RS13550
gene id: 254:EG358_RS13550
uniprot id: A0A381FIE3
names: Cofactor
messages: Binds 1 zinc ion per subunit.

254:EG358 RS11400
gene id: 254:EG358_RS11400
uniprot id: A0A381FF63
names: Similarity
messages: Belongs to the peptidase M16 family.

254:EG358 RS01505
gene id: 254:EG358_RS01505
uniprot id: A0A381F6J1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS04685
gene id: 254:EG358_RS04685
uniprot id: A0A381F8B5
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

254:EG358 RS03130
gene id: 254:EG358_RS03130
uniprot id: A0A381FL57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

254:EG358 RS01565
gene id: 254:EG358_RS01565
uniprot id: A0A381F697
names: Similarity
messages: Belongs to the peptidase S41A family.

254:EG358 RS01325
gene id: 254:EG358_RS01325
uniprot id: A0A381F654
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

254:EG358 RS02860
gene id: 254:EG358_RS02860
uniprot id: A0A381F6Y1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS00235
gene id: 254:EG358_RS00235
uniprot id: A0A381F5F7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

254:EG358 RS11440
gene id: 254:EG358_RS11440
uniprot id: A0A381FF57
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

254:EG358 RS12645
gene id: 254:EG358_RS12645
uniprot id: A0A381FGB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

254:EG358 RS10630
gene id: 254:EG358_RS10630
uniprot id: A0A381FE98
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

254:EG358 RS11680
gene id: 254:EG358_RS11680
uniprot id: A0A381FFH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

254:EG358 RS04655
gene id: 254:EG358_RS04655
uniprot id: A0A381F894
names: Similarity
messages: Belongs to the SusD family.

254:EG358 RS08925
gene id: 254:EG358_RS08925
uniprot id: A0A381FG73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required for cell division and gliding motility.

254:EG358 RS18460
gene id: 254:EG358_RS18460
uniprot id: A0A381JRU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

254:EG358 RS12025
gene id: 254:EG358_RS12025
uniprot id: A0A381FFQ3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

254:EG358 RS13990
gene id: 254:EG358_RS13990
uniprot id: A0A381F3Y2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

254:EG358 RS05770
gene id: 254:EG358_RS05770
uniprot id: A0A381F8Y3
names: Similarity
messages: Belongs to the pirin family.

254:EG358 RS11095
gene id: 254:EG358_RS11095
uniprot id: A0A381FEY8
names: Similarity
messages: Belongs to the SusD family.

254:EG358 RS06245
gene id: 254:EG358_RS06245
uniprot id: A0A381FIC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

254:EG358 RS15155
gene id: 254:EG358_RS15155
uniprot id: A0A381F4L9
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

254:EG358 RS05500
gene id: 254:EG358_RS05500
uniprot id: A0A381F8T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

254:EG358 RS01715
gene id: 254:EG358_RS01715
uniprot id: A0A381F6N0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS06130
gene id: 254:EG358_RS06130
uniprot id: A0A381F9A0
names: Similarity
messages: Belongs to the aspartokinase family.

254:EG358 RS05050
gene id: 254:EG358_RS05050
uniprot id: A0A381F8F8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

254:EG358 RS16295
gene id: 254:EG358_RS16295
uniprot id: A0A381F5A5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS11605
gene id: 254:EG358_RS11605
uniprot id: A0A381FFF5
names: Similarity
messages: Belongs to the UPF0758 family.

254:EG358 RS17270
gene id: 254:EG358_RS17270
uniprot id: A0A381FNN6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

254:EG358 RS04665
gene id: 254:EG358_RS04665
uniprot id: A0A381F827
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

254:EG358 RS06585
gene id: 254:EG358_RS06585
uniprot id: A0A381F9M2
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS17960
gene id: 254:EG358_RS17960
uniprot id: A0A381JR15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

254:EG358 RS09320
gene id: 254:EG358_RS09320
uniprot id: A0A381FD31
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

254:EG358 RS09840
gene id: 254:EG358_RS09840
uniprot id: A0A381FDD6
names: Similarity
messages: Belongs to the AHA1 family.

254:EG358 RS04935
gene id: 254:EG358_RS04935
uniprot id: A0A381FJ95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

254:EG358 RS05430
gene id: 254:EG358_RS05430
uniprot id: A0A381F8R7
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

254:EG358 RS18200
gene id: 254:EG358_RS18200
uniprot id: A0A381FMX7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

254:EG358 RS14570
gene id: 254:EG358_RS14570
uniprot id: A0A381F4J1
names: Cofactor
messages: Binds 2 manganese ions per subunit.

254:EG358 RS03355
gene id: 254:EG358_RS03355
uniprot id: A0A381F7B2
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

254:EG358 RS12195
gene id: 254:EG358_RS12195
uniprot id: A0A381FFW4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

254:EG358 RS04630
gene id: 254:EG358_RS04630
uniprot id: A0A381F815
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

254:EG358 RS18970
gene id: 254:EG358_RS18970
uniprot id: A0A381JTC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

254:EG358 RS09030
gene id: 254:EG358_RS09030
uniprot id: A0A381FDR2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

254:EG358 RS13475
gene id: 254:EG358_RS13475
uniprot id: A0A381FIB5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

254:EG358 RS10525
gene id: 254:EG358_RS10525
uniprot id: A0A381FEC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

254:EG358 RS01900
gene id: 254:EG358_RS01900
uniprot id: A0A381F6H7
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

254:EG358 RS03545
gene id: 254:EG358_RS03545
uniprot id: A0A381F7T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

254:EG358 RS13045
gene id: 254:EG358_RS13045
uniprot id: A0A381FGS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

254:EG358 RS00070
gene id: 254:EG358_RS00070
uniprot id: A0A381F5K2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

254:EG358 RS05745
gene id: 254:EG358_RS05745
uniprot id: A0A381F921
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

254:EG358 RS05035
gene id: 254:EG358_RS05035
uniprot id: A0A381F9V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

254:EG358 RS11790
gene id: 254:EG358_RS11790
uniprot id: A0A381FFM5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS00705
gene id: 254:EG358_RS00705
uniprot id: A0A381F609
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

254:EG358 RS04825
gene id: 254:EG358_RS04825
uniprot id: A0A381F875
names: Caution
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

254:EG358 RS16905
gene id: 254:EG358_RS16905
uniprot id: A0A381JSQ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

254:EG358 RS16335
gene id: 254:EG358_RS16335
uniprot id: A0A381F5K7
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS02110
gene id: 254:EG358_RS02110
uniprot id: A0A381F6W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

254:EG358 RS11485
gene id: 254:EG358_RS11485
uniprot id: A0A381FFD8
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

254:EG358 RS15390
gene id: 254:EG358_RS15390
uniprot id: A0A381FR26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YhhS family.
messages: Cell membrane
messages: Membrane

254:EG358 RS06810
gene id: 254:EG358_RS06810
uniprot id: A0A381FA86
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

254:EG358 RS00290
gene id: 254:EG358_RS00290
uniprot id: A0A381F5J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

254:EG358 RS18190
gene id: 254:EG358_RS18190
uniprot id: A0A381FN11
names: Similarity
messages: Belongs to the ClpX chaperone family.

254:EG358 RS04150
gene id: 254:EG358_RS04150
uniprot id: A0A381FJU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

254:EG358 RS13575
gene id: 254:EG358_RS13575
uniprot id: A0A381FIF1
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

254:EG358 RS08610
gene id: 254:EG358_RS08610
uniprot id: A0A381FC71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

254:EG358 RS03520
gene id: 254:EG358_RS03520
uniprot id: A0A381FJZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

254:EG358 RS03555
gene id: 254:EG358_RS03555
uniprot id: A0A381FK86
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

254:EG358 RS09815
gene id: 254:EG358_RS09815
uniprot id: A0A381FDB4
names: Similarity
messages: Belongs to the AHA1 family.

254:EG358 RS01490
gene id: 254:EG358_RS01490
uniprot id: A0A381F6B7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

254:EG358 RS16890
gene id: 254:EG358_RS16890
uniprot id: A0A381JR89
names: Similarity
messages: Belongs to the peptidase S8 family.

254:EG358 RS00275
gene id: 254:EG358_RS00275
uniprot id: A0A381F5V1
names: Similarity
messages: Belongs to the catalase family.

254:EG358 RS16100
gene id: 254:EG358_RS16100
uniprot id: A0A381FPF4
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

254:EG358 RS17920
gene id: 254:EG358_RS17920
uniprot id: A0A381JR04
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

254:EG358 RS18600
gene id: 254:EG358_RS18600
uniprot id: A0A381JTA8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

254:EG358 RS02850
gene id: 254:EG358_RS02850
uniprot id: A0A381F782
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

254:EG358 RS01595
gene id: 254:EG358_RS01595
uniprot id: A0A381F6J0
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS05130
gene id: 254:EG358_RS05130
uniprot id: A0A381F8U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

254:EG358 RS04470
gene id: 254:EG358_RS04470
uniprot id: A0A381FJC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

254:EG358 RS15470
gene id: 254:EG358_RS15470
uniprot id: A0A381F4S3
names: Similarity
messages: Belongs to the NAD synthetase family.

254:EG358 RS04485
gene id: 254:EG358_RS04485
uniprot id: A0A381F867
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

254:EG358 RS13940
gene id: 254:EG358_RS13940
uniprot id: A0A381F3W9
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

254:EG358 RS19275
gene id: 254:EG358_RS19275
uniprot id: A0A381FMF5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

254:EG358 RS15040
gene id: 254:EG358_RS15040
uniprot id: A0A381F4R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

254:EG358 RS08400
gene id: 254:EG358_RS08400
uniprot id: A0A381FBY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

254:EG358 RS18845
gene id: 254:EG358_RS18845
uniprot id: A0A381JS18
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS04365
gene id: 254:EG358_RS04365
uniprot id: A0A381FJQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

254:EG358 RS15560
gene id: 254:EG358_RS15560
uniprot id: A0A381F535
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

254:EG358 RS01370
gene id: 254:EG358_RS01370
uniprot id: A0A381FM85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

254:EG358 RS13240
gene id: 254:EG358_RS13240
uniprot id: A0A381FH61
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

254:EG358 RS06645
gene id: 254:EG358_RS06645
uniprot id: A0A381FB53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

254:EG358 RS00960
gene id: 254:EG358_RS00960
uniprot id: A0A381F5V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

254:EG358 RS09575
gene id: 254:EG358_RS09575
uniprot id: A0A381FD49
names: Similarity
messages: Belongs to the type IA topoisomerase family.

254:EG358 RS15670
gene id: 254:EG358_RS15670
uniprot id: A0A381F680
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

254:EG358 RS17755
gene id: 254:EG358_RS17755
uniprot id: A0A381JSF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

254:EG358 RS02345
gene id: 254:EG358_RS02345
uniprot id: A0A381F6U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

254:EG358 RS19465
gene id: 254:EG358_RS19465
uniprot id: A0A381F6N3
names: Similarity
messages: Belongs to the Skp family.

254:EG358 RS14535
gene id: 254:EG358_RS14535
uniprot id: A0A381F4E5
names: Similarity
messages: Belongs to the Dps family.

254:EG358 RS02875
gene id: 254:EG358_RS02875
uniprot id: A0A381F8D1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

254:EG358 RS03230
gene id: 254:EG358_RS03230
uniprot id: A0A381F7L0
names: Similarity
messages: Belongs to the SusD family.

254:EG358 RS16360
gene id: 254:EG358_RS16360
uniprot id: A0A381F571
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.

254:EG358 RS13435
gene id: 254:EG358_RS13435
uniprot id: A0A381FH39
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

254:EG358 RS17090
gene id: 254:EG358_RS17090
uniprot id: A0A381JPX7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

254:EG358 RS03415
gene id: 254:EG358_RS03415
uniprot id: A0A381FK16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

254:EG358 RS10290
gene id: 254:EG358_RS10290
uniprot id: A0A381FDW0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Monomer. Binds crRNA and tracrRNA.

254:EG358 RS04785
gene id: 254:EG358_RS04785
uniprot id: A0A381F9L3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

254:EG358 RS10310
gene id: 254:EG358_RS10310
uniprot id: A0A381FDU8
names: Similarity
messages: Belongs to the peptidase C56 family.

254:EG358 RS16995
gene id: 254:EG358_RS16995
uniprot id: A0A381JRV2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

254:EG358 RS09000
gene id: 254:EG358_RS09000
uniprot id: A0A381FCD7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

254:EG358 RS16290
gene id: 254:EG358_RS16290
uniprot id: A0A381F5C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

254:EG358 RS03655
gene id: 254:EG358_RS03655
uniprot id: A0A381F7M5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

254:EG358 RS19135
gene id: 254:EG358_RS19135
uniprot id: A0A381FMB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

254:EG358 RS15215
gene id: 254:EG358_RS15215
uniprot id: A0A381F4V5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

254:EG358 RS03620
gene id: 254:EG358_RS03620
uniprot id: A0A381F7S3
names: Similarity
messages: Belongs to the citrate synthase family.

254:EG358 RS14215
gene id: 254:EG358_RS14215
uniprot id: A0A381F412
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

254:EG358 RS11210
gene id: 254:EG358_RS11210
uniprot id: A0A381FEY6
names: Similarity
messages: Belongs to the AHA1 family.

254:EG358 RS05685
gene id: 254:EG358_RS05685
uniprot id: A0A381F965
names: Similarity
messages: Belongs to the asparaginase 1 family.

254:EG358 RS03275
gene id: 254:EG358_RS03275
uniprot id: A0A381F7G5
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

254:EG358 RS03165
gene id: 254:EG358_RS03165
uniprot id: A0A381F780
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

254:EG358 RS00795
gene id: 254:EG358_RS00795
uniprot id: A0A381F5V3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

254:EG358 RS05620
gene id: 254:EG358_RS05620
uniprot id: A0A381F8V5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

254:EG358 RS15945
gene id: 254:EG358_RS15945
uniprot id: A0A381F5C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

254:EG358 RS18575
gene id: 254:EG358_RS18575
uniprot id: A0A381JS72
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

254:EG358 RS18505
gene id: 254:EG358_RS18505
uniprot id: A0A381JQN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

254:EG358 RS18325
gene id: 254:EG358_RS18325
uniprot id: A0A381JQW5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

254:EG358 RS10435
gene id: 254:EG358_RS10435
uniprot id: A0A381FE01
names: Similarity
messages: Belongs to the GARS family.

254:EG358 RS17795
gene id: 254:EG358_RS17795
uniprot id: A0A381JQM0
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS16160
gene id: 254:EG358_RS16160
uniprot id: A0A381F5F9
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS05330
gene id: 254:EG358_RS05330
uniprot id: A0A381F8T7
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

254:EG358 RS03385
gene id: 254:EG358_RS03385
uniprot id: A0A381F8N9
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

254:EG358 RS13145
gene id: 254:EG358_RS13145
uniprot id: A0A381FH24
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS12285
gene id: 254:EG358_RS12285
uniprot id: A0A381FFY7
names: Similarity
messages: Belongs to the DEAD box helicase family.

254:EG358 RS19825
gene id: 254:EG358_RS19825
uniprot id: A0A381FD29
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

254:EG358 RS12525
gene id: 254:EG358_RS12525
uniprot id: A0A381FG86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

254:EG358 RS18645
gene id: 254:EG358_RS18645
uniprot id: A0A381JQQ6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

254:EG358 RS10365
gene id: 254:EG358_RS10365
uniprot id: A0A381FE70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

254:EG358 RS16300
gene id: 254:EG358_RS16300
uniprot id: A0A381F5G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

254:EG358 RS16440
gene id: 254:EG358_RS16440
uniprot id: A0A381FP87
names: Similarity
messages: Belongs to the sigma-54 factor family.

254:EG358 RS17470
gene id: 254:EG358_RS17470
uniprot id: A0A381FNE4
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

254:EG358 RS04360
gene id: 254:EG358_RS04360
uniprot id: A0A381F833
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS03495
gene id: 254:EG358_RS03495
uniprot id: A0A381F7R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

254:EG358 RS11935
gene id: 254:EG358_RS11935
uniprot id: A0A381FFN3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

254:EG358 RS17225
gene id: 254:EG358_RS17225
uniprot id: A0A381JPY2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

254:EG358 RS02220
gene id: 254:EG358_RS02220
uniprot id: A0A381F6N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

254:EG358 RS10530
gene id: 254:EG358_RS10530
uniprot id: A0A381FE53
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

254:EG358 RS12235
gene id: 254:EG358_RS12235
uniprot id: A0A381FG51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

254:EG358 RS08590
gene id: 254:EG358_RS08590
uniprot id: A0A381FBX8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

254:EG358 RS08650
gene id: 254:EG358_RS08650
uniprot id: A0A381FCA7
names: Similarity
messages: Belongs to the peptidase M24B family.

254:EG358 RS19455
gene id: 254:EG358_RS19455
uniprot id: A0A381F5C0
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

254:EG358 RS16260
gene id: 254:EG358_RS16260
uniprot id: A0A381F548
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

254:EG358 RS01125
gene id: 254:EG358_RS01125
uniprot id: A0A381F796
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

254:EG358 RS18445
gene id: 254:EG358_RS18445
uniprot id: A0A381JRA0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

254:EG358 RS16930
gene id: 254:EG358_RS16930
uniprot id: A0A381JSG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

254:EG358 RS00270
gene id: 254:EG358_RS00270
uniprot id: A0A381F5S3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

254:EG358 RS11475
gene id: 254:EG358_RS11475
uniprot id: A0A381FF95
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

254:EG358 RS09755
gene id: 254:EG358_RS09755
uniprot id: A0A381FDC5
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

254:EG358 RS11795
gene id: 254:EG358_RS11795
uniprot id: A0A381FFJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

254:EG358 RS15475
gene id: 254:EG358_RS15475
uniprot id: A0A381F4S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease N1/T1 family.
messages: Secreted

254:EG358 RS16070
gene id: 254:EG358_RS16070
uniprot id: A0A381F512
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

254:EG358 RS03600
gene id: 254:EG358_RS03600
uniprot id: A0A381FJU8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

254:EG358 RS13540
gene id: 254:EG358_RS13540
uniprot id: A0A381FHI2
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

254:EG358 RS05510
gene id: 254:EG358_RS05510
uniprot id: A0A381FA79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

254:EG358 RS13055
gene id: 254:EG358_RS13055
uniprot id: A0A381FGS9
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS05580
gene id: 254:EG358_RS05580
uniprot id: A0A381F8U7
names: Similarity
messages: Belongs to the HSP15 family.

254:EG358 RS19035
gene id: 254:EG358_RS19035
uniprot id: A0A381JQY4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

254:EG358 RS13080
gene id: 254:EG358_RS13080
uniprot id: A0A381F909
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

254:EG358 RS00550
gene id: 254:EG358_RS00550
uniprot id: A0A381F5Y2
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS18945
gene id: 254:EG358_RS18945
uniprot id: A0A381JTH4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

254:EG358 RS11205
gene id: 254:EG358_RS11205
uniprot id: A0A381FEY4
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS05350
gene id: 254:EG358_RS05350
uniprot id: A0A381FA36
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS08190
gene id: 254:EG358_RS08190
uniprot id: A0A381FBP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

254:EG358 RS10595
gene id: 254:EG358_RS10595
uniprot id: A0A381FE92
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

254:EG358 RS17115
gene id: 254:EG358_RS17115
uniprot id: A0A381FNK4
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

254:EG358 RS07610
gene id: 254:EG358_RS07610
uniprot id: A0A381FAU3
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

254:EG358 RS06575
gene id: 254:EG358_RS06575
uniprot id: A0A381F9R2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

254:EG358 RS11405
gene id: 254:EG358_RS11405
uniprot id: A0A381FF68
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

254:EG358 RS16165
gene id: 254:EG358_RS16165
uniprot id: A0A381F532
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

254:EG358 RS10050
gene id: 254:EG358_RS10050
uniprot id: A0A381FDN2
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS02300
gene id: 254:EG358_RS02300
uniprot id: A0A381F6R0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

254:EG358 RS17200
gene id: 254:EG358_RS17200
uniprot id: A0A381JS49
names: Similarity
messages: Belongs to the YjdM family.

254:EG358 RS11970
gene id: 254:EG358_RS11970
uniprot id: A0A381FFR3
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

254:EG358 RS00535
gene id: 254:EG358_RS00535
uniprot id: A0A381FLT6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

254:EG358 RS13185
gene id: 254:EG358_RS13185
uniprot id: A0A381FGV0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

254:EG358 RS02895
gene id: 254:EG358_RS02895
uniprot id: A0A381F731
names: Similarity
messages: Belongs to the LOG family.

254:EG358 RS11000
gene id: 254:EG358_RS11000
uniprot id: A0A381FES3
names: Similarity
messages: Belongs to the nitroreductase family.

254:EG358 RS18750
gene id: 254:EG358_RS18750
uniprot id: A0A381JQU4
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

254:EG358 RS00035
gene id: 254:EG358_RS00035
uniprot id: A0A381F5Q0
names: Similarity
messages: Belongs to the peptidase M16 family.

254:EG358 RS01200
gene id: 254:EG358_RS01200
uniprot id: A0A381F6E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

254:EG358 RS00665
gene id: 254:EG358_RS00665
uniprot id: A0A381F5U5
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

254:EG358 RS10520
gene id: 254:EG358_RS10520
uniprot id: A0A381FFA1
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

254:EG358 RS05665
gene id: 254:EG358_RS05665
uniprot id: A0A381F8W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

254:EG358 RS00860
gene id: 254:EG358_RS00860
uniprot id: A0A381F5T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

254:EG358 RS03810
gene id: 254:EG358_RS03810
uniprot id: A0A381F7J4
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

254:EG358 RS04120
gene id: 254:EG358_RS04120
uniprot id: A0A381F7Q7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

254:EG358 RS11395
gene id: 254:EG358_RS11395
uniprot id: A0A381FFD6
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

254:EG358 RS18470
gene id: 254:EG358_RS18470
uniprot id: A0A381FMQ9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

254:EG358 RS14300
gene id: 254:EG358_RS14300
uniprot id: A0A381F3Z2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS12370
gene id: 254:EG358_RS12370
uniprot id: A0A381FG43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

254:EG358 RS07515
gene id: 254:EG358_RS07515
uniprot id: A0A381FAK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

254:EG358 RS12565
gene id: 254:EG358_RS12565
uniprot id: A0A381FHF4
names: Similarity
messages: Belongs to the DtxR/MntR family.

254:EG358 RS00845
gene id: 254:EG358_RS00845
uniprot id: A0A381F5X1
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

254:EG358 RS17105
gene id: 254:EG358_RS17105
uniprot id: A0A381JSB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

254:EG358 RS12725
gene id: 254:EG358_RS12725
uniprot id: A0A381FGM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

254:EG358 RS01775
gene id: 254:EG358_RS01775
uniprot id: A0A381F6E1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

254:EG358 RS17680
gene id: 254:EG358_RS17680
uniprot id: A0A381JQ73
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

254:EG358 RS11585
gene id: 254:EG358_RS11585
uniprot id: A0A381FGH4
names: Similarity
messages: Belongs to the peptidase S13 family.

254:EG358 RS16400
gene id: 254:EG358_RS16400
uniprot id: A0A3G6NA95
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

254:EG358 RS02320
gene id: 254:EG358_RS02320
uniprot id: A0A381F6Q6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

254:EG358 RS09935
gene id: 254:EG358_RS09935
uniprot id: A0A381FDH4
names: Similarity
messages: Belongs to the FPG family.

254:EG358 RS16980
gene id: 254:EG358_RS16980
uniprot id: A0A381JTS7
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS04990
gene id: 254:EG358_RS04990
uniprot id: A0A381F8Q3
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

254:EG358 RS17765
gene id: 254:EG358_RS17765
uniprot id: A0A381FNK5
names: Similarity
messages: Belongs to the YicC/YloC family.

254:EG358 RS01265
gene id: 254:EG358_RS01265
uniprot id: A0A381FLH5
names: Similarity
messages: Belongs to the DinB family.

254:EG358 RS00975
gene id: 254:EG358_RS00975
uniprot id: A0A381F770
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

254:EG358 RS17145
gene id: 254:EG358_RS17145
uniprot id: A0A381JQA0
names: Similarity
messages: Belongs to the LOG family.

254:EG358 RS04830
gene id: 254:EG358_RS04830
uniprot id: A0A381F8J8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS10650
gene id: 254:EG358_RS10650
uniprot id: A0A381FEA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

254:EG358 RS17785
gene id: 254:EG358_RS17785
uniprot id: A0A381JRH4
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

254:EG358 RS17360
gene id: 254:EG358_RS17360
uniprot id: A0A381JRK7
names: Similarity
messages: Belongs to the universal stress protein A family.

254:EG358 RS19125
gene id: 254:EG358_RS19125
uniprot id: A0A381JSH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

254:EG358 RS03550
gene id: 254:EG358_RS03550
uniprot id: A0A381F7K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

254:EG358 RS07845
gene id: 254:EG358_RS07845
uniprot id: A0A381FAY4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

254:EG358 RS10580
gene id: 254:EG358_RS10580
uniprot id: A0A381FEC6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

254:EG358 RS15160
gene id: 254:EG358_RS15160
uniprot id: A0A381F4S2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

254:EG358 RS03215
gene id: 254:EG358_RS03215
uniprot id: A0A3G6PF61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

254:EG358 RS00395
gene id: 254:EG358_RS00395
uniprot id: A0A381F6X9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS08505
gene id: 254:EG358_RS08505
uniprot id: A0A381FBU1
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

254:EG358 RS19295
gene id: 254:EG358_RS19295
uniprot id: A0A381JTP0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

254:EG358 RS18795
gene id: 254:EG358_RS18795
uniprot id: A0A381JS07
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

254:EG358 RS06135
gene id: 254:EG358_RS06135
uniprot id: A0A381F9B0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS02710
gene id: 254:EG358_RS02710
uniprot id: A0A381F6V2
names: Similarity
messages: Belongs to the AHA1 family.

254:EG358 RS04810
gene id: 254:EG358_RS04810
uniprot id: A0A381F877
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

254:EG358 RS09375
gene id: 254:EG358_RS09375
uniprot id: A0A381FCY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

254:EG358 RS03955
gene id: 254:EG358_RS03955
uniprot id: A0A381F7S1
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS11520
gene id: 254:EG358_RS11520
uniprot id: A0A381FF96
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

254:EG358 RS05055
gene id: 254:EG358_RS05055
uniprot id: A0A381F8S5
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS04350
gene id: 254:EG358_RS04350
uniprot id: A0A381F7Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

254:EG358 RS03340
gene id: 254:EG358_RS03340
uniprot id: A0A381FK00
names: Similarity
messages: Belongs to the RutC family.

254:EG358 RS04845
gene id: 254:EG358_RS04845
uniprot id: A0A381F8I2
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS03260
gene id: 254:EG358_RS03260
uniprot id: A0A381F795
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

254:EG358 RS15555
gene id: 254:EG358_RS15555
uniprot id: A0A381F4Z8
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

254:EG358 RS16095
gene id: 254:EG358_RS16095
uniprot id: A0A381F5G0
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

254:EG358 RS17620
gene id: 254:EG358_RS17620
uniprot id: A0A381FN83
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

254:EG358 RS11955
gene id: 254:EG358_RS11955
uniprot id: A0A381FFQ9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

254:EG358 RS14260
gene id: 254:EG358_RS14260
uniprot id: A0A381F425
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

254:EG358 RS14330
gene id: 254:EG358_RS14330
uniprot id: A0A381F438
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

254:EG358 RS07685
gene id: 254:EG358_RS07685
uniprot id: A0A381FAS8
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS03420
gene id: 254:EG358_RS03420
uniprot id: A0A381FK52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

254:EG358 RS15770
gene id: 254:EG358_RS15770
uniprot id: A0A381F579
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

254:EG358 RS17670
gene id: 254:EG358_RS17670
uniprot id: A0A381JQV6
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

254:EG358 RS17335
gene id: 254:EG358_RS17335
uniprot id: A0A381JR78
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

254:EG358 RS10425
gene id: 254:EG358_RS10425
uniprot id: A0A381FF55
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS12875
gene id: 254:EG358_RS12875
uniprot id: A0A381FGK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

254:EG358 RS05710
gene id: 254:EG358_RS05710
uniprot id: A0A381F981
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

254:EG358 RS06090
gene id: 254:EG358_RS06090
uniprot id: A0A381F9J3
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS13495
gene id: 254:EG358_RS13495
uniprot id: A0A381F8C2
names: Similarity
messages: Belongs to the CvfB family.

254:EG358 RS11295
gene id: 254:EG358_RS11295
uniprot id: A0A381FF03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

254:EG358 RS12580
gene id: 254:EG358_RS12580
uniprot id: A0A381FG83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

254:EG358 RS19030
gene id: 254:EG358_RS19030
uniprot id: A0A381JRL0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

254:EG358 RS17020
gene id: 254:EG358_RS17020
uniprot id: A0A381JR94
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

254:EG358 RS16520
gene id: 254:EG358_RS16520
uniprot id: A0A381JSP7
names: Similarity
messages: Belongs to the nitroreductase family.

254:EG358 RS00255
gene id: 254:EG358_RS00255
uniprot id: A0A381FMC6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

254:EG358 RS02835
gene id: 254:EG358_RS02835
uniprot id: A0A381F7D0
names: Similarity
messages: Belongs to the nitroreductase family.

254:EG358 RS00890
gene id: 254:EG358_RS00890
uniprot id: A0A381F602
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS10780
gene id: 254:EG358_RS10780
uniprot id: A0A381FEM5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS03660
gene id: 254:EG358_RS03660
uniprot id: A0A381F7G9
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

254:EG358 RS04815
gene id: 254:EG358_RS04815
uniprot id: A0A3G6MZM8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

254:EG358 RS08635
gene id: 254:EG358_RS08635
uniprot id: A0A381FC33
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS00065
gene id: 254:EG358_RS00065
uniprot id: A0A381F5S0
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS00790
gene id: 254:EG358_RS00790
uniprot id: A0A381FLN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

254:EG358 RS00340
gene id: 254:EG358_RS00340
uniprot id: A0A381F5K9
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

254:EG358 RS03490
gene id: 254:EG358_RS03490
uniprot id: A0A381F7L1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

254:EG358 RS09525
gene id: 254:EG358_RS09525
uniprot id: A0A381FD87
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

254:EG358 RS07520
gene id: 254:EG358_RS07520
uniprot id: A0A381FAM5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

254:EG358 RS02190
gene id: 254:EG358_RS02190
uniprot id: A0A381F6Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

254:EG358 RS03535
gene id: 254:EG358_RS03535
uniprot id: A0A3G6P3P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

254:EG358 RS11985
gene id: 254:EG358_RS11985
uniprot id: A0A381FFP9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

254:EG358 RS01520
gene id: 254:EG358_RS01520
uniprot id: A0A381F688
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

254:EG358 RS15590
gene id: 254:EG358_RS15590
uniprot id: A0A381F4W9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS03920
gene id: 254:EG358_RS03920
uniprot id: A0A381F7X8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

254:EG358 RS13140
gene id: 254:EG358_RS13140
uniprot id: A0A381FGS8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

254:EG358 RS06295
gene id: 254:EG358_RS06295
uniprot id: A0A381F9F6
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS11780
gene id: 254:EG358_RS11780
uniprot id: A0A381FBB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

254:EG358 RS15935
gene id: 254:EG358_RS15935
uniprot id: A0A381F6D1
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS03000
gene id: 254:EG358_RS03000
uniprot id: A0A381F7D5
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

254:EG358 RS18115
gene id: 254:EG358_RS18115
uniprot id: A0A381JQF8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

254:EG358 RS06790
gene id: 254:EG358_RS06790
uniprot id: A0A381FA31
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

254:EG358 RS11735
gene id: 254:EG358_RS11735
uniprot id: A0A381FFH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

254:EG358 RS17205
gene id: 254:EG358_RS17205
uniprot id: A0A381JSD6
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS12045
gene id: 254:EG358_RS12045
uniprot id: A0A381FFT0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

254:EG358 RS12095
gene id: 254:EG358_RS12095
uniprot id: A0A381FFU4
names: Similarity
messages: Belongs to the ribF family.

254:EG358 RS05540
gene id: 254:EG358_RS05540
uniprot id: A0A381F955
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

254:EG358 RS12695
gene id: 254:EG358_RS12695
uniprot id: A0A381FGF5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

254:EG358 RS14115
gene id: 254:EG358_RS14115
uniprot id: A0A381F3Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

254:EG358 RS18890
gene id: 254:EG358_RS18890
uniprot id: A0A381FMH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

254:EG358 RS00885
gene id: 254:EG358_RS00885
uniprot id: A0A381F683
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

254:EG358 RS03525
gene id: 254:EG358_RS03525
uniprot id: A0A381FJZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

254:EG358 RS07710
gene id: 254:EG358_RS07710
uniprot id: A0A381FB61
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

254:EG358 RS14600
gene id: 254:EG358_RS14600
uniprot id: A0A381F487
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

254:EG358 RS00405
gene id: 254:EG358_RS00405
uniprot id: A0A381F5Y3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

254:EG358 RS19540
gene id: 254:EG358_RS19540
uniprot id: A0A381F5L4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

254:EG358 RS18010
gene id: 254:EG358_RS18010
uniprot id: A0A381JR22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

254:EG358 RS09745
gene id: 254:EG358_RS09745
uniprot id: A0A381FD82
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

254:EG358 RS19040
gene id: 254:EG358_RS19040
uniprot id: A0A381JQY2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

254:EG358 RS14250
gene id: 254:EG358_RS14250
uniprot id: A0A381F3Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

254:EG358 RS12955
gene id: 254:EG358_RS12955
uniprot id: A0A381FGN4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

254:EG358 RS00445
gene id: 254:EG358_RS00445
uniprot id: A0A381F6Y9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

254:EG358 RS15045
gene id: 254:EG358_RS15045
uniprot id: A0A381F4T6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

254:EG358 RS05385
gene id: 254:EG358_RS05385
uniprot id: A0A381F8V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

254:EG358 RS05470
gene id: 254:EG358_RS05470
uniprot id: A0A381F964
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

254:EG358 RS04660
gene id: 254:EG358_RS04660
uniprot id: A0A381F8D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

254:EG358 RS02845
gene id: 254:EG358_RS02845
uniprot id: A0A381F725
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

254:EG358 RS15125
gene id: 254:EG358_RS15125
uniprot id: A0A381F4K9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS05110
gene id: 254:EG358_RS05110
uniprot id: A0A381FIY6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

254:EG358 RS01480
gene id: 254:EG358_RS01480
uniprot id: A0A381F6G2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

254:EG358 RS14255
gene id: 254:EG358_RS14255
uniprot id: A0A381F422
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

254:EG358 RS05175
gene id: 254:EG358_RS05175
uniprot id: A0A381F8P8
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

254:EG358 RS10690
gene id: 254:EG358_RS10690
uniprot id: A0A381FEE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

254:EG358 RS11565
gene id: 254:EG358_RS11565
uniprot id: A0A381FB85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

254:EG358 RS15600
gene id: 254:EG358_RS15600
uniprot id: A0A381F511
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

254:EG358 RS10665
gene id: 254:EG358_RS10665
uniprot id: A0A381FEA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

254:EG358 RS00585
gene id: 254:EG358_RS00585
uniprot id: A0A381F5P9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS08180
gene id: 254:EG358_RS08180
uniprot id: A0A381FBP1
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

254:EG358 RS05605
gene id: 254:EG358_RS05605
uniprot id: A0A381F962
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

254:EG358 RS10175
gene id: 254:EG358_RS10175
uniprot id: A0A381FEW3
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

254:EG358 RS16175
gene id: 254:EG358_RS16175
uniprot id: A0A381F575
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

254:EG358 RS11580
gene id: 254:EG358_RS11580
uniprot id: A0A381FFC5
names: Similarity
messages: Belongs to the peptidase S51 family.

254:EG358 RS13545
gene id: 254:EG358_RS13545
uniprot id: A0A381FHA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

254:EG358 RS12640
gene id: 254:EG358_RS12640
uniprot id: A0A381FGK2
names: Similarity
messages: Belongs to the AHA1 family.

254:EG358 RS17515
gene id: 254:EG358_RS17515
uniprot id: A0A381JQS9
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS12985
gene id: 254:EG358_RS12985
uniprot id: A0A381FGT3
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS00950
gene id: 254:EG358_RS00950
uniprot id: A0A381F650
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

254:EG358 RS14335
gene id: 254:EG358_RS14335
uniprot id: A0A381F447
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

254:EG358 RS02100
gene id: 254:EG358_RS02100
uniprot id: A0A381F6L4
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

254:EG358 RS18350
gene id: 254:EG358_RS18350
uniprot id: A0A381JQL7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

254:EG358 RS16340
gene id: 254:EG358_RS16340
uniprot id: A0A381FQD3
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS18840
gene id: 254:EG358_RS18840
uniprot id: A0A381JTF4
names: Similarity
messages: Belongs to the NusB family.

254:EG358 RS15570
gene id: 254:EG358_RS15570
uniprot id: A0A381F4U0
names: Similarity
messages: Belongs to the SusD family.

254:EG358 RS14075
gene id: 254:EG358_RS14075
uniprot id: A0A381F490
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

254:EG358 RS14520
gene id: 254:EG358_RS14520
uniprot id: A0A381F479
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

254:EG358 RS19480
gene id: 254:EG358_RS19480
uniprot id: A0A381F5H0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

254:EG358 RS17935
gene id: 254:EG358_RS17935
uniprot id: A0A381JRJ9
names: Similarity
messages: Belongs to the heat shock protein 90 family.

254:EG358 RS08920
gene id: 254:EG358_RS08920
uniprot id: A0A381FCB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

254:EG358 RS11920
gene id: 254:EG358_RS11920
uniprot id: A0A381FFK2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

254:EG358 RS18650
gene id: 254:EG358_RS18650
uniprot id: A0A381JTC1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

254:EG358 RS03485
gene id: 254:EG358_RS03485
uniprot id: A0A381F8R1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

254:EG358 RS03565
gene id: 254:EG358_RS03565
uniprot id: A0A381F7Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

254:EG358 RS12550
gene id: 254:EG358_RS12550
uniprot id: A0A381FGI3
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

254:EG358 RS15835
gene id: 254:EG358_RS15835
uniprot id: A0A3G6ND45
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS17315
gene id: 254:EG358_RS17315
uniprot id: A0A381FNH3
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.

254:EG358 RS03705
gene id: 254:EG358_RS03705
uniprot id: A0A381F7M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

254:EG358 RS13160
gene id: 254:EG358_RS13160
uniprot id: A0A381FAC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

254:EG358 RS17610
gene id: 254:EG358_RS17610
uniprot id: A0A381JSL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

254:EG358 RS10315
gene id: 254:EG358_RS10315
uniprot id: A0A381FDX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

254:EG358 RS13365
gene id: 254:EG358_RS13365
uniprot id: A0A381FH32
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS14070
gene id: 254:EG358_RS14070
uniprot id: A0A3G6MWG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

254:EG358 RS17275
gene id: 254:EG358_RS17275
uniprot id: A0A381JPZ6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

254:EG358 RS01745
gene id: 254:EG358_RS01745
uniprot id: A0A381FL01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

254:EG358 RS15575
gene id: 254:EG358_RS15575
uniprot id: A0A381F4U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

254:EG358 RS06155
gene id: 254:EG358_RS06155
uniprot id: A0A381F9L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

254:EG358 RS13075
gene id: 254:EG358_RS13075
uniprot id: A0A381F927
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

254:EG358 RS19185
gene id: 254:EG358_RS19185
uniprot id: A0A381FMA4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

254:EG358 RS17815
gene id: 254:EG358_RS17815
uniprot id: A0A381JQY7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

254:EG358 RS01130
gene id: 254:EG358_RS01130
uniprot id: A0A381F693
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS13245
gene id: 254:EG358_RS13245
uniprot id: A0A381FGX0
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

254:EG358 RS07750
gene id: 254:EG358_RS07750
uniprot id: A0A381FB64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

254:EG358 RS15065
gene id: 254:EG358_RS15065
uniprot id: A0A381F4S4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

254:EG358 RS17155
gene id: 254:EG358_RS17155
uniprot id: A0A381JSC6
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

254:EG358 RS15450
gene id: 254:EG358_RS15450
uniprot id: A0A381F4T5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

254:EG358 RS16065
gene id: 254:EG358_RS16065
uniprot id: A0A381F5D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

254:EG358 RS02265
gene id: 254:EG358_RS02265
uniprot id: A0A381FKR1
names: Similarity
messages: Belongs to the class-D beta-lactamase family.

254:EG358 RS07595
gene id: 254:EG358_RS07595
uniprot id: A0A381FAP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

254:EG358 RS09010
gene id: 254:EG358_RS09010
uniprot id: A0A381FCM7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

254:EG358 RS05155
gene id: 254:EG358_RS05155
uniprot id: A0A381FK09
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS05010
gene id: 254:EG358_RS05010
uniprot id: A0A381F8T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

254:EG358 RS02205
gene id: 254:EG358_RS02205
uniprot id: A0A381F6U9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

254:EG358 RS00330
gene id: 254:EG358_RS00330
uniprot id: A0A381F5I5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

254:EG358 RS01300
gene id: 254:EG358_RS01300
uniprot id: A0A381F675
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

254:EG358 RS06015
gene id: 254:EG358_RS06015
uniprot id: A0A381F985
names: Similarity
messages: Belongs to the peptidase M1 family.

254:EG358 RS12120
gene id: 254:EG358_RS12120
uniprot id: A0A381FFY8
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

254:EG358 RS15885
gene id: 254:EG358_RS15885
uniprot id: A0A381F510
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

254:EG358 RS19005
gene id: 254:EG358_RS19005
uniprot id: A0A381JR03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

254:EG358 RS06040
gene id: 254:EG358_RS06040
uniprot id: A0A381F990
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

254:EG358 RS01970
gene id: 254:EG358_RS01970
uniprot id: A0A381F6I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

254:EG358 RS02585
gene id: 254:EG358_RS02585
uniprot id: A0A3G6NYK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

254:EG358 RS04410
gene id: 254:EG358_RS04410
uniprot id: A0A381F843
names: Function
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

254:EG358 RS08265
gene id: 254:EG358_RS08265
uniprot id: A0A381FBS3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

254:EG358 RS13085
gene id: 254:EG358_RS13085
uniprot id: A0A381F991
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

254:EG358 RS10575
gene id: 254:EG358_RS10575
uniprot id: A0A381FE78
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

254:EG358 RS04285
gene id: 254:EG358_RS04285
uniprot id: A0A381F980
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

254:EG358 RS01770
gene id: 254:EG358_RS01770
uniprot id: A0A381FKZ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS03515
gene id: 254:EG358_RS03515
uniprot id: A0A381F7P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

254:EG358 RS02070
gene id: 254:EG358_RS02070
uniprot id: A0A381F6L2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

254:EG358 RS05780
gene id: 254:EG358_RS05780
uniprot id: A0A381F928
names: Similarity
messages: Belongs to the pirin family.

254:EG358 RS01455
gene id: 254:EG358_RS01455
uniprot id: A0A381F6I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

254:EG358 RS10760
gene id: 254:EG358_RS10760
uniprot id: A0A381FEH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

254:EG358 RS06145
gene id: 254:EG358_RS06145
uniprot id: A0A381F9D9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

254:EG358 RS04245
gene id: 254:EG358_RS04245
uniprot id: A0A381F865
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

254:EG358 RS07530
gene id: 254:EG358_RS07530
uniprot id: A0A381FAZ6
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS11490
gene id: 254:EG358_RS11490
uniprot id: A0A381FF78
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

254:EG358 RS09180
gene id: 254:EG358_RS09180
uniprot id: A0A381FCM5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

254:EG358 RS03205
gene id: 254:EG358_RS03205
uniprot id: A0A381F781
names: Similarity
messages: Belongs to the fabD family.

254:EG358 RS16510
gene id: 254:EG358_RS16510
uniprot id: A0A381JRU3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

254:EG358 RS03965
gene id: 254:EG358_RS03965
uniprot id: A0A381F7V0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

254:EG358 RS10570
gene id: 254:EG358_RS10570
uniprot id: A0A381FE73
names: Similarity
messages: Belongs to the peptidase S8 family.

254:EG358 RS15410
gene id: 254:EG358_RS15410
uniprot id: A0A381F4M2
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

254:EG358 RS01245
gene id: 254:EG358_RS01245
uniprot id: A0A381F6B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

254:EG358 RS12100
gene id: 254:EG358_RS12100
uniprot id: A0A381FG10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

254:EG358 RS03835
gene id: 254:EG358_RS03835
uniprot id: A0A381F7L9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

254:EG358 RS01805
gene id: 254:EG358_RS01805
uniprot id: A0A381F6M8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

254:EG358 RS08830
gene id: 254:EG358_RS08830
uniprot id: A0A381FCF3
names: Similarity
messages: Belongs to the peptidase S8 family.

254:EG358 RS04040
gene id: 254:EG358_RS04040
uniprot id: A0A381F929
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

254:EG358 RS10890
gene id: 254:EG358_RS10890
uniprot id: A0A381FDI6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

254:EG358 RS02050
gene id: 254:EG358_RS02050
uniprot id: A0A381F6K5
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS02650
gene id: 254:EG358_RS02650
uniprot id: A0A381F740
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS15135
gene id: 254:EG358_RS15135
uniprot id: A0A381FQL7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

254:EG358 RS10080
gene id: 254:EG358_RS10080
uniprot id: A0A381FDQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

254:EG358 RS02745
gene id: 254:EG358_RS02745
uniprot id: A0A381F704
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS13995
gene id: 254:EG358_RS13995
uniprot id: A0A381F435
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

254:EG358 RS04380
gene id: 254:EG358_RS04380
uniprot id: A0A381F7W7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

254:EG358 RS11950
gene id: 254:EG358_RS11950
uniprot id: A0A381FFU5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS00390
gene id: 254:EG358_RS00390
uniprot id: A0A381F5M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

254:EG358 RS07780
gene id: 254:EG358_RS07780
uniprot id: A0A381FAW3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

254:EG358 RS13065
gene id: 254:EG358_RS13065
uniprot id: A0A381FGN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

254:EG358 RS08695
gene id: 254:EG358_RS08695
uniprot id: A0A381FC99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

254:EG358 RS09885
gene id: 254:EG358_RS09885
uniprot id: A0A381FEK1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

254:EG358 RS00280
gene id: 254:EG358_RS00280
uniprot id: A0A381F5H5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

254:EG358 RS04585
gene id: 254:EG358_RS04585
uniprot id: A0A381F842
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

254:EG358 RS17380
gene id: 254:EG358_RS17380
uniprot id: A0A381JSM0
names: Similarity
messages: Belongs to the peptidase M16 family.

254:EG358 RS01475
gene id: 254:EG358_RS01475
uniprot id: A0A381F7G2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

254:EG358 RS11850
gene id: 254:EG358_RS11850
uniprot id: A0A381FFK6
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

254:EG358 RS11020
gene id: 254:EG358_RS11020
uniprot id: A0A381FEP5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

254:EG358 RS07495
gene id: 254:EG358_RS07495
uniprot id: A0A381FAL6
names: Similarity
messages: Belongs to the bacterial glucokinase family.

254:EG358 RS09555
gene id: 254:EG358_RS09555
uniprot id: A0A381FD39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

254:EG358 RS11815
gene id: 254:EG358_RS11815
uniprot id: A0A381FFR5
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS07545
gene id: 254:EG358_RS07545
uniprot id: A0A381FAP8
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

254:EG358 RS14390
gene id: 254:EG358_RS14390
uniprot id: A0A381F411
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

254:EG358 RS03470
gene id: 254:EG358_RS03470
uniprot id: A0A381FK10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

254:EG358 RS11515
gene id: 254:EG358_RS11515
uniprot id: A0A381FFD9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

254:EG358 RS14035
gene id: 254:EG358_RS14035
uniprot id: A0A381F3X9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

254:EG358 RS02615
gene id: 254:EG358_RS02615
uniprot id: A0A381F6W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

254:EG358 RS14140
gene id: 254:EG358_RS14140
uniprot id: A0A381F3Z9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

254:EG358 RS08140
gene id: 254:EG358_RS08140
uniprot id: A0A381FBN9
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

254:EG358 RS13305
gene id: 254:EG358_RS13305
uniprot id: A0A381FGY1
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

254:EG358 RS10615
gene id: 254:EG358_RS10615
uniprot id: A0A381FE93
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS18510
gene id: 254:EG358_RS18510
uniprot id: A0A381JTA0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

254:EG358 RS03570
gene id: 254:EG358_RS03570
uniprot id: A0A381FJY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

254:EG358 RS17970
gene id: 254:EG358_RS17970
uniprot id: A0A381JQE0
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

254:EG358 RS02255
gene id: 254:EG358_RS02255
uniprot id: A0A3G6P5Q3
names: Similarity
messages: Belongs to the MreC family.

254:EG358 RS16850
gene id: 254:EG358_RS16850
uniprot id: A0A381JRX5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

254:EG358 RS03580
gene id: 254:EG358_RS03580
uniprot id: A0A381FK20
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

254:EG358 RS01085
gene id: 254:EG358_RS01085
uniprot id: A0A381F6C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

254:EG358 RS01120
gene id: 254:EG358_RS01120
uniprot id: A0A381F617
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

254:EG358 RS04395
gene id: 254:EG358_RS04395
uniprot id: A0A381F898
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

254:EG358 RS12975
gene id: 254:EG358_RS12975
uniprot id: A0A381FGK9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

254:EG358 RS08950
gene id: 254:EG358_RS08950
uniprot id: A0A381FCL6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

254:EG358 RS03135
gene id: 254:EG358_RS03135
uniprot id: A0A381F7B7
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

254:EG358 RS03305
gene id: 254:EG358_RS03305
uniprot id: A0A381F7G4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

254:EG358 RS10235
gene id: 254:EG358_RS10235
uniprot id: A0A381FDS0
names: Function
messages: Might have a role analogous to that of eukaryotic histone proteins.

254:EG358 RS03360
gene id: 254:EG358_RS03360
uniprot id: A0A381F7H4
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

254:EG358 RS03510
gene id: 254:EG358_RS03510
uniprot id: A0A381F7K1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

254:EG358 RS01405
gene id: 254:EG358_RS01405
uniprot id: A0A381F6H1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

254:EG358 RS11355
gene id: 254:EG358_RS11355
uniprot id: A0A381FF50
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

254:EG358 RS12805
gene id: 254:EG358_RS12805
uniprot id: A0A381FGH8
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

254:EG358 RS07335
gene id: 254:EG358_RS07335
uniprot id: A0A381FBX4
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

254:EG358 RS16410
gene id: 254:EG358_RS16410
uniprot id: A0A381F582
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

254:EG358 RS17450
gene id: 254:EG358_RS17450
uniprot id: A0A381JS97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

254:EG358 RS16900
gene id: 254:EG358_RS16900
uniprot id: A0A381JRW8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

254:EG358 RS15075
gene id: 254:EG358_RS15075
uniprot id: A0A381F4J7
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS17625
gene id: 254:EG358_RS17625
uniprot id: A0A381FN71
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

254:EG358 RS01630
gene id: 254:EG358_RS01630
uniprot id: A0A381F6I3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

254:EG358 RS12825
gene id: 254:EG358_RS12825
uniprot id: A0A381FGI6
names: Similarity
messages: Belongs to the DapB family.

254:EG358 RS09750
gene id: 254:EG358_RS09750
uniprot id: A0A381FET7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

254:EG358 RS11360
gene id: 254:EG358_RS11360
uniprot id: A0A381FF92
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS03400
gene id: 254:EG358_RS03400
uniprot id: A0A381F7G7
names: Similarity
messages: Belongs to the Dps family.

254:EG358 RS08615
gene id: 254:EG358_RS08615
uniprot id: A0A381FBX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

254:EG358 RS14925
gene id: 254:EG358_RS14925
uniprot id: A0A381F4G2
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

254:EG358 RS11230
gene id: 254:EG358_RS11230
uniprot id: A0A381FEY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

254:EG358 RS06830
gene id: 254:EG358_RS06830
uniprot id: A0A381F9X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

254:EG358 RS10915
gene id: 254:EG358_RS10915
uniprot id: A0A381FEK5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

254:EG358 RS03240
gene id: 254:EG358_RS03240
uniprot id: A0A381F792
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

254:EG358 RS14970
gene id: 254:EG358_RS14970
uniprot id: A0A381F4H7
names: Similarity
messages: Belongs to the pirin family.

254:EG358 RS02670
gene id: 254:EG358_RS02670
uniprot id: A0A381F6X4
names: Similarity
messages: Belongs to the thioesterase PaaI family.

254:EG358 RS11710
gene id: 254:EG358_RS11710
uniprot id: A0A381FFJ0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

254:EG358 RS18805
gene id: 254:EG358_RS18805
uniprot id: A0A381JR64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

254:EG358 RS14445
gene id: 254:EG358_RS14445
uniprot id: A0A381F460
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

254:EG358 RS04415
gene id: 254:EG358_RS04415
uniprot id: A0A381FJP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

254:EG358 RS05030
gene id: 254:EG358_RS05030
uniprot id: A0A381FJ20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

254:EG358 RS08745
gene id: 254:EG358_RS08745
uniprot id: A0A381FCB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

254:EG358 RS11545
gene id: 254:EG358_RS11545
uniprot id: A0A381FFJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

254:EG358 RS02805
gene id: 254:EG358_RS02805
uniprot id: A0A381F797
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS00320
gene id: 254:EG358_RS00320
uniprot id: A0A381F5T3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

254:EG358 RS00835
gene id: 254:EG358_RS00835
uniprot id: A0A381F667
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

254:EG358 RS03845
gene id: 254:EG358_RS03845
uniprot id: A0A381F7T9
names: Similarity
messages: Belongs to the disproportionating enzyme family.

254:EG358 RS17015
gene id: 254:EG358_RS17015
uniprot id: A0A381JRI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

254:EG358 RS05160
gene id: 254:EG358_RS05160
uniprot id: A0A381F8I8
names: Similarity
messages: Belongs to the peptidase S8 family.

254:EG358 RS06440
gene id: 254:EG358_RS06440
uniprot id: A0A381FI87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

254:EG358 RS03195
gene id: 254:EG358_RS03195
uniprot id: A0A381F7E9
names: Similarity
messages: Belongs to the BshC family.

254:EG358 RS11635
gene id: 254:EG358_RS11635
uniprot id: A0A381FFM4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

254:EG358 RS10775
gene id: 254:EG358_RS10775
uniprot id: A0A381FFK7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

254:EG358 RS18850
gene id: 254:EG358_RS18850
uniprot id: A0A381JQX1
names: Subcellular Location Annotation
messages: Nucleus

254:EG358 RS06530
gene id: 254:EG358_RS06530
uniprot id: A0A381F9W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

254:EG358 RS03605
gene id: 254:EG358_RS03605
uniprot id: A0A381F7L6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

254:EG358 RS01945
gene id: 254:EG358_RS01945
uniprot id: A0A381F6L1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

254:EG358 RS15260
gene id: 254:EG358_RS15260
uniprot id: A0A381F4U7
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

254:EG358 RS05295
gene id: 254:EG358_RS05295
uniprot id: A0A381FA18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

254:EG358 RS15190
gene id: 254:EG358_RS15190
uniprot id: A0A381F4V7
names: Similarity
messages: Belongs to the GbsR family.

254:EG358 RS14275
gene id: 254:EG358_RS14275
uniprot id: A0A381F4E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

254:EG358 RS08810
gene id: 254:EG358_RS08810
uniprot id: A0A381FC77
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

254:EG358 RS08145
gene id: 254:EG358_RS08145
uniprot id: A0A381FBB5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

254:EG358 RS01540
gene id: 254:EG358_RS01540
uniprot id: A0A381F6C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

254:EG358 RS10360
gene id: 254:EG358_RS10360
uniprot id: A0A381FDZ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

254:EG358 RS10750
gene id: 254:EG358_RS10750
uniprot id: A0A381FEK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

254:EG358 RS01160
gene id: 254:EG358_RS01160
uniprot id: A0A381FLB8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

254:EG358 RS15425
gene id: 254:EG358_RS15425
uniprot id: A0A381F624
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

254:EG358 RS14985
gene id: 254:EG358_RS14985
uniprot id: A0A381F4Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

254:EG358 RS03935
gene id: 254:EG358_RS03935
uniprot id: A0A381F7N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

254:EG358 RS06660
gene id: 254:EG358_RS06660
uniprot id: A0A381FA24
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS17745
gene id: 254:EG358_RS17745
uniprot id: A0A381JQ91
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

254:EG358 RS00580
gene id: 254:EG358_RS00580
uniprot id: A0A381F5N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

254:EG358 RS07445
gene id: 254:EG358_RS07445
uniprot id: A0A381FAK3
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

254:EG358 RS04240
gene id: 254:EG358_RS04240
uniprot id: A0A381F822
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

254:EG358 RS14025
gene id: 254:EG358_RS14025
uniprot id: A0A381F482
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

254:EG358 RS02985
gene id: 254:EG358_RS02985
uniprot id: A0A381F788
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

254:EG358 RS12270
gene id: 254:EG358_RS12270
uniprot id: A0A381FG39
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

254:EG358 RS09085
gene id: 254:EG358_RS09085
uniprot id: A0A381FCM0
names: Similarity
messages: Belongs to the peptidase S13 family.

254:EG358 RS08765
gene id: 254:EG358_RS08765
uniprot id: A0A381FC93
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

254:EG358 RS07820
gene id: 254:EG358_RS07820
uniprot id: A0A381FGM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

254:EG358 RS15920
gene id: 254:EG358_RS15920
uniprot id: A0A381F4Y2
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

254:EG358 RS11510
gene id: 254:EG358_RS11510
uniprot id: A0A381FBA6
names: Similarity
messages: Belongs to the SUI1 family.

254:EG358 RS03910
gene id: 254:EG358_RS03910
uniprot id: A0A381F7L4
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

254:EG358 RS17535
gene id: 254:EG358_RS17535
uniprot id: A0A381JRB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS14095
gene id: 254:EG358_RS14095
uniprot id: A0A381F456
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

254:EG358 RS19305
gene id: 254:EG358_RS19305
uniprot id: A0A381FMD7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

254:EG358 RS17215
gene id: 254:EG358_RS17215
uniprot id: A0A381JQM1
names: Similarity
messages: Belongs to the asparagine synthetase family.

254:EG358 RS16845
gene id: 254:EG358_RS16845
uniprot id: A0A381JR97
names: Similarity
messages: Belongs to the thioredoxin family.

254:EG358 RS11965
gene id: 254:EG358_RS11965
uniprot id: A0A381FFL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

254:EG358 RS06350
gene id: 254:EG358_RS06350
uniprot id: A0A381F9S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

254:EG358 RS18740
gene id: 254:EG358_RS18740
uniprot id: A0A381JQS3
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS03480
gene id: 254:EG358_RS03480
uniprot id: A0A381FK42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

254:EG358 RS02840
gene id: 254:EG358_RS02840
uniprot id: A0A381F762
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

254:EG358 RS01445
gene id: 254:EG358_RS01445
uniprot id: A0A381F692
names: Similarity
messages: Belongs to the peptidase S66 family.

254:EG358 RS04980
gene id: 254:EG358_RS04980
uniprot id: A0A381FJ87
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

254:EG358 RS00495
gene id: 254:EG358_RS00495
uniprot id: A0A381F6Z9
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS04965
gene id: 254:EG358_RS04965
uniprot id: A0A381F8K4
names: Similarity
messages: Belongs to the peptidase S8 family.

254:EG358 RS18615
gene id: 254:EG358_RS18615
uniprot id: A0A381JR17
names: Similarity
messages: Belongs to the pyruvate kinase family.

254:EG358 RS10420
gene id: 254:EG358_RS10420
uniprot id: A0A381FE06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

254:EG358 RS18485
gene id: 254:EG358_RS18485
uniprot id: A0A381FMZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

254:EG358 RS03145
gene id: 254:EG358_RS03145
uniprot id: A0A381F7D9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

254:EG358 RS15315
gene id: 254:EG358_RS15315
uniprot id: A0A381FPW2
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

254:EG358 RS05995
gene id: 254:EG358_RS05995
uniprot id: A0A381FAM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

254:EG358 RS19050
gene id: 254:EG358_RS19050
uniprot id: A0A381JS59
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

254:EG358 RS19170
gene id: 254:EG358_RS19170
uniprot id: A0A381JTG1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS05835
gene id: 254:EG358_RS05835
uniprot id: A0A381F9C2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

254:EG358 RS14425
gene id: 254:EG358_RS14425
uniprot id: A0A381F473
names: Similarity
messages: Belongs to the ArsC family.

254:EG358 RS05700
gene id: 254:EG358_RS05700
uniprot id: A0A381F8W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

254:EG358 RS12145
gene id: 254:EG358_RS12145
uniprot id: A0A381FFU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

254:EG358 RS13260
gene id: 254:EG358_RS13260
uniprot id: A0A381FGY4
names: Similarity
messages: Belongs to the peptidase M17 family.

254:EG358 RS02270
gene id: 254:EG358_RS02270
uniprot id: A0A381FKL3
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS12720
gene id: 254:EG358_RS12720
uniprot id: A0A381FGD3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS04475
gene id: 254:EG358_RS04475
uniprot id: A0A381F9B8
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

254:EG358 RS11980
gene id: 254:EG358_RS11980
uniprot id: A0A381FFP2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

254:EG358 RS17585
gene id: 254:EG358_RS17585
uniprot id: A0A381JRC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

254:EG358 RS11560
gene id: 254:EG358_RS11560
uniprot id: A0A381FFG6
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS17280
gene id: 254:EG358_RS17280
uniprot id: A0A381JSK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

254:EG358 RS07580
gene id: 254:EG358_RS07580
uniprot id: A0A381FB26
names: Similarity
messages: Belongs to the peptidase M16 family.

254:EG358 RS00700
gene id: 254:EG358_RS00700
uniprot id: A0A381F728
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

254:EG358 RS11960
gene id: 254:EG358_RS11960
uniprot id: A0A381FFN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

254:EG358 RS04925
gene id: 254:EG358_RS04925
uniprot id: A0A381F8B6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

254:EG358 RS14130
gene id: 254:EG358_RS14130
uniprot id: A0A381F499
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

254:EG358 RS00615
gene id: 254:EG358_RS00615
uniprot id: A0A381F5T6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

254:EG358 RS17285
gene id: 254:EG358_RS17285
uniprot id: A0A381FNF8
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

254:EG358 RS00655
gene id: 254:EG358_RS00655
uniprot id: A0A381F640
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

254:EG358 RS18000
gene id: 254:EG358_RS18000
uniprot id: A0A381JSU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

254:EG358 RS03500
gene id: 254:EG358_RS03500
uniprot id: A0A381F7I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

254:EG358 RS17950
gene id: 254:EG358_RS17950
uniprot id: A0A381JSI6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

254:EG358 RS15375
gene id: 254:EG358_RS15375
uniprot id: A0A381F618
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

254:EG358 RS10735
gene id: 254:EG358_RS10735
uniprot id: A0A381FEK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

254:EG358 RS06060
gene id: 254:EG358_RS06060
uniprot id: A0A381F9C1
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS10540
gene id: 254:EG358_RS10540
uniprot id: A0A381FE64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

254:EG358 RS01780
gene id: 254:EG358_RS01780
uniprot id: A0A381F7M0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS11470
gene id: 254:EG358_RS11470
uniprot id: A0A381FFG9
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

254:EG358 RS02045
gene id: 254:EG358_RS02045
uniprot id: A0A381F6N2
names: Similarity
messages: Belongs to the DprA/Smf family.

254:EG358 RS18385
gene id: 254:EG358_RS18385
uniprot id: A0A381JT07
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

254:EG358 RS13060
gene id: 254:EG358_RS13060
uniprot id: A0A381FGW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

254:EG358 RS10295
gene id: 254:EG358_RS10295
uniprot id: A0A381FDW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

254:EG358 RS18885
gene id: 254:EG358_RS18885
uniprot id: A0A381JQV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

254:EG358 RS02635
gene id: 254:EG358_RS02635
uniprot id: A0A381F786
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

254:EG358 RS08885
gene id: 254:EG358_RS08885
uniprot id: A0A381FC94
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

254:EG358 RS09230
gene id: 254:EG358_RS09230
uniprot id: A0A381FCU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

254:EG358 RS03505
gene id: 254:EG358_RS03505
uniprot id: A0A381FK97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

254:EG358 RS11700
gene id: 254:EG358_RS11700
uniprot id: A0A381FFR8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

254:EG358 RS17770
gene id: 254:EG358_RS17770
uniprot id: A0A381JQX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

254:EG358 RS14515
gene id: 254:EG358_RS14515
uniprot id: A0A381F4I6
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS13535
gene id: 254:EG358_RS13535
uniprot id: A0A381FH98
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

254:EG358 RS01100
gene id: 254:EG358_RS01100
uniprot id: A0A381F677
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

254:EG358 RS15330
gene id: 254:EG358_RS15330
uniprot id: A0A381F606
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

254:EG358 RS06025
gene id: 254:EG358_RS06025
uniprot id: A0A381F9I9
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

254:EG358 RS00555
gene id: 254:EG358_RS00555
uniprot id: A0A381F619
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

254:EG358 RS17835
gene id: 254:EG358_RS17835
uniprot id: A0A381FNA2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: In the C-terminal section; belongs to the OMP decarboxylase family.
messages: In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS04175
gene id: 254:EG358_RS04175
uniprot id: A0A381F7R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

254:EG358 RS04370
gene id: 254:EG358_RS04370
uniprot id: A0A381F7V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

254:EG358 RS02765
gene id: 254:EG358_RS02765
uniprot id: A0A381F6Z8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

254:EG358 RS03160
gene id: 254:EG358_RS03160
uniprot id: A0A381F776
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

254:EG358 RS03830
gene id: 254:EG358_RS03830
uniprot id: A0A381F7K5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

254:EG358 RS14110
gene id: 254:EG358_RS14110
uniprot id: A0A381F3V2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS03410
gene id: 254:EG358_RS03410
uniprot id: A0A381F7I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

254:EG358 RS05490
gene id: 254:EG358_RS05490
uniprot id: A0A381F937
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

254:EG358 RS13100
gene id: 254:EG358_RS13100
uniprot id: A0A381FGQ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

254:EG358 RS18785
gene id: 254:EG358_RS18785
uniprot id: A0A381JQT3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS01435
gene id: 254:EG358_RS01435
uniprot id: A0A381F6K1
names: Similarity
messages: Belongs to the UPF0102 family.

254:EG358 RS11885
gene id: 254:EG358_RS11885
uniprot id: A0A381FFL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

254:EG358 RS03730
gene id: 254:EG358_RS03730
uniprot id: A0A381F7I7
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS13165
gene id: 254:EG358_RS13165
uniprot id: A0A381FGW8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

254:EG358 RS14325
gene id: 254:EG358_RS14325
uniprot id: A0A381F4F0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

254:EG358 RS01040
gene id: 254:EG358_RS01040
uniprot id: A0A381F626
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

254:EG358 RS03815
gene id: 254:EG358_RS03815
uniprot id: A0A381F7S0
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

254:EG358 RS05785
gene id: 254:EG358_RS05785
uniprot id: A0A381F963
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS10430
gene id: 254:EG358_RS10430
uniprot id: A0A381FE87
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

254:EG358 RS02865
gene id: 254:EG358_RS02865
uniprot id: A0A381F720
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS01440
gene id: 254:EG358_RS01440
uniprot id: A0A381F6A7
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS10440
gene id: 254:EG358_RS10440
uniprot id: A0A381FE45
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

254:EG358 RS04205
gene id: 254:EG358_RS04205
uniprot id: A0A381F7R6
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

254:EG358 RS00565
gene id: 254:EG358_RS00565
uniprot id: A0A381F5S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

254:EG358 RS01090
gene id: 254:EG358_RS01090
uniprot id: A0A381F637
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

254:EG358 RS07405
gene id: 254:EG358_RS07405
uniprot id: A0A381FH43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

254:EG358 RS04465
gene id: 254:EG358_RS04465
uniprot id: A0A381F7X2
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS02760
gene id: 254:EG358_RS02760
uniprot id: A0A381F6V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

254:EG358 RS02245
gene id: 254:EG358_RS02245
uniprot id: A0A381F6S3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

254:EG358 RS09045
gene id: 254:EG358_RS09045
uniprot id: A0A381FCR0
names: Similarity
messages: Belongs to the DinB family.

254:EG358 RS02095
gene id: 254:EG358_RS02095
uniprot id: A0A381F6P1
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS13870
gene id: 254:EG358_RS13870
uniprot id: A0A381F452
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS02015
gene id: 254:EG358_RS02015
uniprot id: A0A381F6H0
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS00490
gene id: 254:EG358_RS00490
uniprot id: A0A381F5P0
names: Similarity
messages: Belongs to the asparagine synthetase family.

254:EG358 RS07745
gene id: 254:EG358_RS07745
uniprot id: A0A381FGR9
names: Similarity
messages: Belongs to the UPF0111 family.

254:EG358 RS05000
gene id: 254:EG358_RS05000
uniprot id: A0A381F8E5
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

254:EG358 RS01390
gene id: 254:EG358_RS01390
uniprot id: A0A381F6I5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

254:EG358 RS16240
gene id: 254:EG358_RS16240
uniprot id: A0A381F5B4
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS09485
gene id: 254:EG358_RS09485
uniprot id: A0A381FD01
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

254:EG358 RS08820
gene id: 254:EG358_RS08820
uniprot id: A0A381FCH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

254:EG358 RS07640
gene id: 254:EG358_RS07640
uniprot id: A0A381FAR5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

254:EG358 RS16945
gene id: 254:EG358_RS16945
uniprot id: A0A381JR82
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

254:EG358 RS09110
gene id: 254:EG358_RS09110
uniprot id: A0A381FCL0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

254:EG358 RS02790
gene id: 254:EG358_RS02790
uniprot id: A0A381F744
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS04130
gene id: 254:EG358_RS04130
uniprot id: A0A381FKL8
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

254:EG358 RS12105
gene id: 254:EG358_RS12105
uniprot id: A0A381FFR6
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

254:EG358 RS00215
gene id: 254:EG358_RS00215
uniprot id: A0A381F5N6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

254:EG358 RS12440
gene id: 254:EG358_RS12440
uniprot id: A0A381FG33
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

254:EG358 RS09315
gene id: 254:EG358_RS09315
uniprot id: A0A381FD23
names: Similarity
messages: Belongs to the nitroreductase family.

254:EG358 RS01150
gene id: 254:EG358_RS01150
uniprot id: A0A3G6NYV6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

254:EG358 RS17760
gene id: 254:EG358_RS17760
uniprot id: A0A381JSQ1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

254:EG358 RS02920
gene id: 254:EG358_RS02920
uniprot id: A0A381F8E1
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

254:EG358 RS18900
gene id: 254:EG358_RS18900
uniprot id: A0A381JS29
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS00760
gene id: 254:EG358_RS00760
uniprot id: A0A381F657
names: Similarity
messages: Belongs to the beta-eliminating lyase family.

254:EG358 RS02025
gene id: 254:EG358_RS02025
uniprot id: A0A381F6J6
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS08690
gene id: 254:EG358_RS08690
uniprot id: A0A381FG98
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

254:EG358 RS03155
gene id: 254:EG358_RS03155
uniprot id: A0A381F759
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

254:EG358 RS02465
gene id: 254:EG358_RS02465
uniprot id: A0A381F6Q8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

254:EG358 RS18965
gene id: 254:EG358_RS18965
uniprot id: A0A381JT16
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS01620
gene id: 254:EG358_RS01620
uniprot id: A0A381F6A8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS01645
gene id: 254:EG358_RS01645
uniprot id: A0A3G6NXA1
names: Similarity
messages: Belongs to the SufE family.

254:EG358 RS05570
gene id: 254:EG358_RS05570
uniprot id: A0A381F986
names: Similarity
messages: Belongs to the glutamate synthase family.

254:EG358 RS12215
gene id: 254:EG358_RS12215
uniprot id: A0A381FFV6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

254:EG358 RS06545
gene id: 254:EG358_RS06545
uniprot id: A0A381F9T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

254:EG358 RS14220
gene id: 254:EG358_RS14220
uniprot id: A0A381F5A2
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS08675
gene id: 254:EG358_RS08675
uniprot id: A0A381FC92
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS06580
gene id: 254:EG358_RS06580
uniprot id: A0A381F9U7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

254:EG358 RS14355
gene id: 254:EG358_RS14355
uniprot id: A0A381F450
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

254:EG358 RS03395
gene id: 254:EG358_RS03395
uniprot id: A0A381F7P4
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

254:EG358 RS00285
gene id: 254:EG358_RS00285
uniprot id: A0A381F5J2
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

254:EG358 RS05435
gene id: 254:EG358_RS05435
uniprot id: A0A381F8Z0
names: Similarity
messages: Belongs to the MQO family.

254:EG358 RS00540
gene id: 254:EG358_RS00540
uniprot id: A0A381F5Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

254:EG358 RS11480
gene id: 254:EG358_RS11480
uniprot id: A0A381FGD0
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

254:EG358 RS03860
gene id: 254:EG358_RS03860
uniprot id: A0A381F7K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

254:EG358 RS18800
gene id: 254:EG358_RS18800
uniprot id: A0A381JQW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

254:EG358 RS11880
gene id: 254:EG358_RS11880
uniprot id: A0A381FFV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

254:EG358 RS13480
gene id: 254:EG358_RS13480
uniprot id: A0A381FH89
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

254:EG358 RS17320
gene id: 254:EG358_RS17320
uniprot id: A0A381JQ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Membrane

254:EG358 RS00345
gene id: 254:EG358_RS00345
uniprot id: A0A381F6X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

254:EG358 RS08935
gene id: 254:EG358_RS08935
uniprot id: A0A381FCG1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

254:EG358 RS10640
gene id: 254:EG358_RS10640
uniprot id: A0A381FET0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

254:EG358 RS03685
gene id: 254:EG358_RS03685
uniprot id: A0A381F7J1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

254:EG358 RS09385
gene id: 254:EG358_RS09385
uniprot id: A0A381FD40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

254:EG358 RS16915
gene id: 254:EG358_RS16915
uniprot id: A0A381JTE0
names: Similarity
messages: Belongs to the ParB family.

254:EG358 RS10300
gene id: 254:EG358_RS10300
uniprot id: A0A381FF09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

254:EG358 RS06495
gene id: 254:EG358_RS06495
uniprot id: A0A381FI00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

254:EG358 RS07320
gene id: 254:EG358_RS07320
uniprot id: A0A381FAJ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

254:EG358 RS18210
gene id: 254:EG358_RS18210
uniprot id: A0A381JT35
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

254:EG358 RS08870
gene id: 254:EG358_RS08870
uniprot id: A0A381FC83
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

254:EG358 RS19340
gene id: 254:EG358_RS19340
uniprot id: A0A381JTP9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

254:EG358 RS12810
gene id: 254:EG358_RS12810
uniprot id: A0A381FGP3
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS14150
gene id: 254:EG358_RS14150
uniprot id: A0A381FRN5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

254:EG358 RS00725
gene id: 254:EG358_RS00725
uniprot id: A0A381F608
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

254:EG358 RS17600
gene id: 254:EG358_RS17600
uniprot id: A0A381JQI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

254:EG358 RS16130
gene id: 254:EG358_RS16130
uniprot id: A0A381F6G6
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

254:EG358 RS04420
gene id: 254:EG358_RS04420
uniprot id: A0A381F7W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

254:EG358 RS17180
gene id: 254:EG358_RS17180
uniprot id: A0A381JSI9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

254:EG358 RS12715
gene id: 254:EG358_RS12715
uniprot id: A0A381FGA6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

254:EG358 RS18100
gene id: 254:EG358_RS18100
uniprot id: A0A381JQG1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

254:EG358 RS04400
gene id: 254:EG358_RS04400
uniprot id: A0A381FJD1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

254:EG358 RS14280
gene id: 254:EG358_RS14280
uniprot id: A0A381F431
names: PTM
messages: Binds 1 heme c group covalently per subunit.

254:EG358 RS14245
gene id: 254:EG358_RS14245
uniprot id: A0A3G6N220
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

254:EG358 RS18725
gene id: 254:EG358_RS18725
uniprot id: A0A381FMJ5
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

254:EG358 RS07395
gene id: 254:EG358_RS07395
uniprot id: A0A381FBZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

254:EG358 RS08385
gene id: 254:EG358_RS08385
uniprot id: A0A381FBL1
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

254:EG358 RS00425
gene id: 254:EG358_RS00425
uniprot id: A0A381F5Z2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

254:EG358 RS11275
gene id: 254:EG358_RS11275
uniprot id: A0A381FF86
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS09400
gene id: 254:EG358_RS09400
uniprot id: A0A381FCX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

254:EG358 RS09965
gene id: 254:EG358_RS09965
uniprot id: A0A381FDE7
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS16115
gene id: 254:EG358_RS16115
uniprot id: A0A381F523
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

254:EG358 RS11995
gene id: 254:EG358_RS11995
uniprot id: A0A381FFV5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS02340
gene id: 254:EG358_RS02340
uniprot id: A0A381F716
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

254:EG358 RS16670
gene id: 254:EG358_RS16670
uniprot id: A0A381JTY9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

254:EG358 RS06655
gene id: 254:EG358_RS06655
uniprot id: A0A381F9S0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

254:EG358 RS00265
gene id: 254:EG358_RS00265
uniprot id: A0A381F5L2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

254:EG358 RS08755
gene id: 254:EG358_RS08755
uniprot id: A0A381FDF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

254:EG358 RS04775
gene id: 254:EG358_RS04775
uniprot id: A0A381F8H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

254:EG358 RS18465
gene id: 254:EG358_RS18465
uniprot id: A0A381JQN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

254:EG358 RS11940
gene id: 254:EG358_RS11940
uniprot id: A0A381FFM8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

254:EG358 RS10820
gene id: 254:EG358_RS10820
uniprot id: A0A381FEI6
names: Similarity
messages: Belongs to the UxaA family.

254:EG358 RS05135
gene id: 254:EG358_RS05135
uniprot id: A0A381FIY5
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

254:EG358 RS01310
gene id: 254:EG358_RS01310
uniprot id: A0A381F6C4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

254:EG358 RS07585
gene id: 254:EG358_RS07585
uniprot id: A0A381FAP2
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

254:EG358 RS06635
gene id: 254:EG358_RS06635
uniprot id: A0A381FA14
names: Similarity
messages: Belongs to the MmpS family.

254:EG358 RS01530
gene id: 254:EG358_RS01530
uniprot id: A0A381F6G8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

254:EG358 RS01870
gene id: 254:EG358_RS01870
uniprot id: A0A381F6G7
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

254:EG358 RS14065
gene id: 254:EG358_RS14065
uniprot id: A0A381F3Y1
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

254:EG358 RS02065
gene id: 254:EG358_RS02065
uniprot id: A0A381F6H8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

254:EG358 RS15415
gene id: 254:EG358_RS15415
uniprot id: A0A381F4R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

254:EG358 RS05480
gene id: 254:EG358_RS05480
uniprot id: A0A381F8S8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

254:EG358 RS05395
gene id: 254:EG358_RS05395
uniprot id: A0A3G6MZD5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

254:EG358 RS09250
gene id: 254:EG358_RS09250
uniprot id: A0A381FCQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

254:EG358 RS01400
gene id: 254:EG358_RS01400
uniprot id: A0A381F682
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

254:EG358 RS15220
gene id: 254:EG358_RS15220
uniprot id: A0A381F4I9
names: Similarity
messages: Belongs to the peptidase C1 family.

254:EG358 RS03540
gene id: 254:EG358_RS03540
uniprot id: A0A381F7M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

254:EG358 RS04675
gene id: 254:EG358_RS04675
uniprot id: A0A381F828
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

254:EG358 RS10950
gene id: 254:EG358_RS10950
uniprot id: A0A381FEM3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

254:EG358 RS09545
gene id: 254:EG358_RS09545
uniprot id: A0A381FD14
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

254:EG358 RS17485
gene id: 254:EG358_RS17485
uniprot id: A0A381JRA5
names: Cofactor
messages: Can also use Mn(2+) ion.

254:EG358 RS02720
gene id: 254:EG358_RS02720
uniprot id: A0A381F6Y4
names: Similarity
messages: Belongs to the peptidase S9A family.

254:EG358 RS16675
gene id: 254:EG358_RS16675
uniprot id: A0A381JRD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

254:EG358 RS04065
gene id: 254:EG358_RS04065
uniprot id: A0A381F7X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

254:EG358 RS08730
gene id: 254:EG358_RS08730
uniprot id: A0A381FDE5
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

254:EG358 RS03595
gene id: 254:EG358_RS03595
uniprot id: A0A381F7P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

254:EG358 RS03780
gene id: 254:EG358_RS03780
uniprot id: A0A381F7J6
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

254:EG358 RS08940
gene id: 254:EG358_RS08940
uniprot id: A0A381FCC4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

254:EG358 RS11460
gene id: 254:EG358_RS11460
uniprot id: A0A381FFC8
names: Similarity
messages: Belongs to the SusD family.

254:EG358 RS17035
gene id: 254:EG358_RS17035
uniprot id: A0A381JR62
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

254:EG358 RS13510
gene id: 254:EG358_RS13510
uniprot id: A0A381FH85
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

254:EG358 RS18605
gene id: 254:EG358_RS18605
uniprot id: A0A381FMS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

254:EG358 RS09265
gene id: 254:EG358_RS09265
uniprot id: A0A381FE20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

254:EG358 RS04180
gene id: 254:EG358_RS04180
uniprot id: A0A381F7T2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

254:EG358 RS10770
gene id: 254:EG358_RS10770
uniprot id: A0A381FEF8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

254:EG358 RS15070
gene id: 254:EG358_RS15070
uniprot id: A0A381F4E4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

254:EG358 RS15505
gene id: 254:EG358_RS15505
uniprot id: A0A381F4Z0
names: Cofactor
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

254:EG358 RS05690
gene id: 254:EG358_RS05690
uniprot id: A0A381F9A6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS14120
gene id: 254:EG358_RS14120
uniprot id: A0A381F3Z1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

254:EG358 RS02965
gene id: 254:EG358_RS02965
uniprot id: A0A381F734
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

254:EG358 RS19195
gene id: 254:EG358_RS19195
uniprot id: A0A381FMQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

254:EG358 RS12055
gene id: 254:EG358_RS12055
uniprot id: A0A381FAQ9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

254:EG358 RS04375
gene id: 254:EG358_RS04375
uniprot id: A0A381F7V4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

254:EG358 RS09005
gene id: 254:EG358_RS09005
uniprot id: A0A381FCF9
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS11455
gene id: 254:EG358_RS11455
uniprot id: A0A381FGC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

254:EG358 RS02405
gene id: 254:EG358_RS02405
uniprot id: A0A381F6Z1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

254:EG358 RS09695
gene id: 254:EG358_RS09695
uniprot id: A0A381FD99
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

254:EG358 RS15485
gene id: 254:EG358_RS15485
uniprot id: A0A381F518
names: Similarity
messages: Belongs to the barstar family.

254:EG358 RS19325
gene id: 254:EG358_RS19325
uniprot id: A0A381JSK4
names: Similarity
messages: Belongs to the EPSP synthase family.

254:EG358 RS15545
gene id: 254:EG358_RS15545
uniprot id: A0A381F4W0
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

254:EG358 RS16330
gene id: 254:EG358_RS16330
uniprot id: A0A381F5I7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

254:EG358 RS12500
gene id: 254:EG358_RS12500
uniprot id: A0A381FHD6
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS17675
gene id: 254:EG358_RS17675
uniprot id: A0A381JQ90
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

254:EG358 RS14955
gene id: 254:EG358_RS14955
uniprot id: A0A381F4N0
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS04440
gene id: 254:EG358_RS04440
uniprot id: A0A381F8B0
names: Similarity
messages: Belongs to the IMPACT family.

254:EG358 RS08080
gene id: 254:EG358_RS08080
uniprot id: A0A381FB94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

254:EG358 RS18920
gene id: 254:EG358_RS18920
uniprot id: A0A381JTA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

254:EG358 RS16190
gene id: 254:EG358_RS16190
uniprot id: A0A381F5A4
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

254:EG358 RS18455
gene id: 254:EG358_RS18455
uniprot id: A0A381JT87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

254:EG358 RS09220
gene id: 254:EG358_RS09220
uniprot id: A0A381FE03
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

254:EG358 RS10150
gene id: 254:EG358_RS10150
uniprot id: A0A381FDT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

254:EG358 RS14305
gene id: 254:EG358_RS14305
uniprot id: A0A381F432
names: Similarity
messages: Belongs to the TrpC family.

254:EG358 RS17955
gene id: 254:EG358_RS17955
uniprot id: A0A381JRW9
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS06320
gene id: 254:EG358_RS06320
uniprot id: A0A381F9F0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

254:EG358 RS12995
gene id: 254:EG358_RS12995
uniprot id: A0A381FGQ0
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

254:EG358 RS17025
gene id: 254:EG358_RS17025
uniprot id: A0A381JSD9
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

254:EG358 RS02040
gene id: 254:EG358_RS02040
uniprot id: A0A381FKR6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

254:EG358 RS14270
gene id: 254:EG358_RS14270
uniprot id: A0A381F4C8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

254:EG358 RS04155
gene id: 254:EG358_RS04155
uniprot id: A0A381F7Q4
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

254:EG358 RS12255
gene id: 254:EG358_RS12255
uniprot id: A0A381FAI3
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

254:EG358 RS07625
gene id: 254:EG358_RS07625
uniprot id: A0A381FAR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

254:EG358 RS13300
gene id: 254:EG358_RS13300
uniprot id: A0A381FH77
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

254:EG358 RS15640
gene id: 254:EG358_RS15640
uniprot id: A0A381F4Y1
names: Subcellular Location Annotation
messages: Secreted

254:EG358 RS03960
gene id: 254:EG358_RS03960
uniprot id: A0A381F7M3
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

254:EG358 RS10600
gene id: 254:EG358_RS10600
uniprot id: A0A381FEA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

254:EG358 RS16430
gene id: 254:EG358_RS16430
uniprot id: A0A381F6M7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

254:EG358 RS15270
gene id: 254:EG358_RS15270
uniprot id: A0A381F4J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

254:EG358 RS15765
gene id: 254:EG358_RS15765
uniprot id: A0A381F552
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

254:EG358 RS12780
gene id: 254:EG358_RS12780
uniprot id: A0A381FGF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

254:EG358 RS04690
gene id: 254:EG358_RS04690
uniprot id: A0A381F8G2
names: Subcellular Location Annotation
messages: Membrane

254:EG358 RS09850
gene id: 254:EG358_RS09850
uniprot id: A0A381FDF6
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

254:EG358 RS03710
gene id: 254:EG358_RS03710
uniprot id: A0A381F7H7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

254:EG358 RS17160
gene id: 254:EG358_RS17160
uniprot id: A0A381JRH5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

254:EG358 RS01430
gene id: 254:EG358_RS01430
uniprot id: A0A381F6F2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

254:EG358 RS01225
gene id: 254:EG358_RS01225
uniprot id: A0A381F612
names: Similarity
messages: Belongs to the phosphohexose mutase family.

254:EG358 RS18140
gene id: 254:EG358_RS18140
uniprot id: A0A381JR39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

254:EG358 RS00165
gene id: 254:EG358_RS00165
uniprot id: A0A381F5M5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

254:EG358 RS02775
gene id: 254:EG358_RS02775
uniprot id: A0A381FKG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

254:EG358 RS15305
gene id: 254:EG358_RS15305
uniprot id: A0A381F4Q8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

254:EG358 RS07080
gene id: 254:EG358_RS07080
uniprot id: A0A381FAF9
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

254:EG358 RS18595
gene id: 254:EG358_RS18595
uniprot id: A0A381JQP5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

254:EG358 RS02140
gene id: 254:EG358_RS02140
uniprot id: A0A381F6X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

254:EG358 RS10945
gene id: 254:EG358_RS10945
uniprot id: A0A381FEQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

254:EG358 RS18665
gene id: 254:EG358_RS18665
uniprot id: A0A381JR30
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

254:EG358 RS17490
gene id: 254:EG358_RS17490
uniprot id: A0A381JQ47
names: Similarity
messages: Belongs to the malate synthase family.

254:EG358 RS03700
gene id: 254:EG358_RS03700
uniprot id: A0A381F7W5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

254:EG358 RS11530
gene id: 254:EG358_RS11530
uniprot id: A0A381FFI9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

254:EG358 RS09550
gene id: 254:EG358_RS09550
uniprot id: A0A381FD37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

254:EG358 RS02980
gene id: 254:EG358_RS02980
uniprot id: A0A381F7F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

254:EG358 RS03125
gene id: 254:EG358_RS03125
uniprot id: A0A381F7D6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

254:EG358 RS02170
gene id: 254:EG358_RS02170
uniprot id: A0A381F6N1
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

254:EG358 RS00900
gene id: 254:EG358_RS00900
uniprot id: A0A381F636
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

254:EG358 RS09860
gene id: 254:EG358_RS09860
uniprot id: A0A381FDJ4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

254:EG358 RS12265
gene id: 254:EG358_RS12265
uniprot id: A0A381FFZ4
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

254:EG358 RS11380
gene id: 254:EG358_RS11380
uniprot id: A0A381FF59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

254:EG358 RS09370
gene id: 254:EG358_RS09370
uniprot id: A0A381FF81
names: Similarity
messages: Belongs to the AlaDH/PNT family.

254:EG358 RS08340
gene id: 254:EG358_RS08340
uniprot id: A0A381FBX3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

254:EG358 RS02280
gene id: 254:EG358_RS02280
uniprot id: A0A381F7Y4
names: Similarity
messages: Belongs to the peptidase C40 family.

254:EG358 RS04780
gene id: 254:EG358_RS04780
uniprot id: A0A381F869
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

254:EG358 RS03150
gene id: 254:EG358_RS03150
uniprot id: A0A381FK17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

254:EG358 RS19470
gene id: 254:EG358_RS19470
uniprot id: A0A381F5L7
names: Similarity
messages: Belongs to the Skp family.

254:EG358 RS12465
gene id: 254:EG358_RS12465
uniprot id: A0A381FG90
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.