2506452:N24 RS04575
gene id: 2506452:N24_RS04575
uniprot id: A0A160PP25
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2506452:N24 RS16170
gene id: 2506452:N24_RS16170
uniprot id: A0A169SDP6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2506452:N24 RS03845
gene id: 2506452:N24_RS03845
uniprot id: A0A169RR46
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

2506452:N24 RS05140
gene id: 2506452:N24_RS05140
uniprot id: A0A160PPH2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

2506452:N24 RS13030
gene id: 2506452:N24_RS13030
uniprot id: A0A161JML7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2506452:N24 RS03245
gene id: 2506452:N24_RS03245
uniprot id: A0A161JLZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2506452:N24 RS01505
gene id: 2506452:N24_RS01505
uniprot id: A0A169RND2
names: Subcellular Location Annotation
messages: Cytoplasm

2506452:N24 RS12290
gene id: 2506452:N24_RS12290
uniprot id: A0A160PRI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2506452:N24 RS05125
gene id: 2506452:N24_RS05125
uniprot id: A0A161JNR8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2506452:N24 RS13210
gene id: 2506452:N24_RS13210
uniprot id: A0A160PSY2
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

2506452:N24 RS07600
gene id: 2506452:N24_RS07600
uniprot id: A0A160PPC0
names: Similarity
messages: Belongs to the UPF0434 family.

2506452:N24 RS03400
gene id: 2506452:N24_RS03400
uniprot id: A0A160PRH4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2506452:N24 RS00465
gene id: 2506452:N24_RS00465
uniprot id: A0A160PMC9
names: Subcellular Location Annotation
messages: Cytoplasm

2506452:N24 RS08575
gene id: 2506452:N24_RS08575
uniprot id: A0A160PPS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2506452:N24 RS03380
gene id: 2506452:N24_RS03380
uniprot id: A0A160PNG8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2506452:N24 RS13035
gene id: 2506452:N24_RS13035
uniprot id: A0A160PRU5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

2506452:N24 RS05110
gene id: 2506452:N24_RS05110
uniprot id: A0A160PN73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

2506452:N24 RS10760
gene id: 2506452:N24_RS10760
uniprot id: A0A160PT46
names: Similarity
messages: Belongs to the P(II) protein family.

2506452:N24 RS05115
gene id: 2506452:N24_RS05115
uniprot id: A0A160PSB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2506452:N24 RS03975
gene id: 2506452:N24_RS03975
uniprot id: A0A160PNQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2506452:N24 RS07470
gene id: 2506452:N24_RS07470
uniprot id: A0A160PQB7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2506452:N24 RS03295
gene id: 2506452:N24_RS03295
uniprot id: A0A169RQF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2506452:N24 RS00760
gene id: 2506452:N24_RS00760
uniprot id: A0A169RME1
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

2506452:N24 RS05120
gene id: 2506452:N24_RS05120
uniprot id: A0A160PR60
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2506452:N24 RS10350
gene id: 2506452:N24_RS10350
uniprot id: A0A160PQN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2506452:N24 RS13595
gene id: 2506452:N24_RS13595
uniprot id: A0A160PT73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

2506452:N24 RS03515
gene id: 2506452:N24_RS03515
uniprot id: A0A160PPS8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2506452:N24 RS12595
gene id: 2506452:N24_RS12595
uniprot id: A0A160PVJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2506452:N24 RS03355
gene id: 2506452:N24_RS03355
uniprot id: A0A160PQC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2506452:N24 RS01220
gene id: 2506452:N24_RS01220
uniprot id: A0A160PMQ2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

2506452:N24 RS02250
gene id: 2506452:N24_RS02250
uniprot id: A0A160PLR7
names: Subcellular Location Annotation
messages: Cytoplasm

2506452:N24 RS03600
gene id: 2506452:N24_RS03600
uniprot id: A0A160PRK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2506452:N24 RS05145
gene id: 2506452:N24_RS05145
uniprot id: A0A160PP89
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2506452:N24 RS13185
gene id: 2506452:N24_RS13185
uniprot id: A0A160PRW6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2506452:N24 RS11275
gene id: 2506452:N24_RS11275
uniprot id: A0A160PTV7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

2506452:N24 RS12285
gene id: 2506452:N24_RS12285
uniprot id: A0A169S1U0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2506452:N24 RS03280
gene id: 2506452:N24_RS03280
uniprot id: A0A160PNM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2506452:N24 RS12315
gene id: 2506452:N24_RS12315
uniprot id: A0A160PSJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

2506452:N24 RS03370
gene id: 2506452:N24_RS03370
uniprot id: A0A160PNG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2506452:N24 RS05815
gene id: 2506452:N24_RS05815
uniprot id: A0A160PRF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2506452:N24 RS04885
gene id: 2506452:N24_RS04885
uniprot id: A0A160PS79
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2506452:N24 RS03795
gene id: 2506452:N24_RS03795
uniprot id: A0A169RR21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2506452:N24 RS02615
gene id: 2506452:N24_RS02615
uniprot id: A0A160PLW9
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

2506452:N24 RS03610
gene id: 2506452:N24_RS03610
uniprot id: A0A161JNN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2506452:N24 RS03395
gene id: 2506452:N24_RS03395
uniprot id: A0A160PME7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.