2492438:G6N19 RS01935
gene id: 2492438:G6N19_RS01935
uniprot id: A0A7I7JJA2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2492438:G6N19 RS18880
gene id: 2492438:G6N19_RS18880
uniprot id: A0A7I7JS78
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

2492438:G6N19 RS02130
gene id: 2492438:G6N19_RS02130
uniprot id: A0A7I7JHZ3
names: Similarity
messages: Belongs to the saccharopine dehydrogenase family. Enoyl reductase subfamily.

2492438:G6N19 RS11540
gene id: 2492438:G6N19_RS11540
uniprot id: A0A7I7JQG0
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

2492438:G6N19 RS17865
gene id: 2492438:G6N19_RS17865
uniprot id: A0A7I7JRZ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

2492438:G6N19 RS18130
gene id: 2492438:G6N19_RS18130
uniprot id: A0A7I7JS22
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2492438:G6N19 RS09815
gene id: 2492438:G6N19_RS09815
uniprot id: A0A7I7JM69
names: Similarity
messages: Belongs to the MmpS family.

2492438:G6N19 RS14510
gene id: 2492438:G6N19_RS14510
uniprot id: A0A7I7JRG7
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

2492438:G6N19 RS00150
gene id: 2492438:G6N19_RS00150
uniprot id: A0A7I7JI85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

2492438:G6N19 RS17025
gene id: 2492438:G6N19_RS17025
uniprot id: A0A7I7JSV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

2492438:G6N19 RS11260
gene id: 2492438:G6N19_RS11260
uniprot id: A0A7I7JMS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

2492438:G6N19 RS10170
gene id: 2492438:G6N19_RS10170
uniprot id: A0A7I7JPL2
names: Similarity
messages: Belongs to the MmpS family.

2492438:G6N19 RS20090
gene id: 2492438:G6N19_RS20090
uniprot id: A0A7I7JSW6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2492438:G6N19 RS12725
gene id: 2492438:G6N19_RS12725
uniprot id: A0A7I7JNT7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

2492438:G6N19 RS16560
gene id: 2492438:G6N19_RS16560
uniprot id: A0A7I7JSP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

2492438:G6N19 RS12735
gene id: 2492438:G6N19_RS12735
uniprot id: A0A7I7JPY1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2492438:G6N19 RS20575
gene id: 2492438:G6N19_RS20575
uniprot id: A0A7I7JT68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

2492438:G6N19 RS03175
gene id: 2492438:G6N19_RS03175
uniprot id: A0A7I7JHZ9
names: Similarity
messages: Belongs to the peptidase S1C family.

2492438:G6N19 RS15950
gene id: 2492438:G6N19_RS15950
uniprot id: A0A7I7JS12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2492438:G6N19 RS20845
gene id: 2492438:G6N19_RS20845
uniprot id: A0A7I7JUW7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

2492438:G6N19 RS19365
gene id: 2492438:G6N19_RS19365
uniprot id: A0A7I7JSQ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS15505
gene id: 2492438:G6N19_RS15505
uniprot id: A0A7I7JS04
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2492438:G6N19 RS14150
gene id: 2492438:G6N19_RS14150
uniprot id: A0A7I7JQZ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

2492438:G6N19 RS12115
gene id: 2492438:G6N19_RS12115
uniprot id: A0A7I7JQ50
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2492438:G6N19 RS13540
gene id: 2492438:G6N19_RS13540
uniprot id: A0A7I7JP85
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

2492438:G6N19 RS18990
gene id: 2492438:G6N19_RS18990
uniprot id: A0A7I7JTH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0353 family.
messages: Cell membrane

2492438:G6N19 RS00330
gene id: 2492438:G6N19_RS00330
uniprot id: A0A7I7JI37
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

2492438:G6N19 RS06475
gene id: 2492438:G6N19_RS06475
uniprot id: A0A7I7JMJ7
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

2492438:G6N19 RS20640
gene id: 2492438:G6N19_RS20640
uniprot id: A0A7I7JIK5
names: Similarity
messages: Belongs to the WXG100 family.

2492438:G6N19 RS06545
gene id: 2492438:G6N19_RS06545
uniprot id: A0A7I7JK14
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

2492438:G6N19 RS08195
gene id: 2492438:G6N19_RS08195
uniprot id: A0A7I7JKX5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

2492438:G6N19 RS16645
gene id: 2492438:G6N19_RS16645
uniprot id: A0A7I7JS75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

2492438:G6N19 RS02385
gene id: 2492438:G6N19_RS02385
uniprot id: A0A7I7JI54
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2492438:G6N19 RS20275
gene id: 2492438:G6N19_RS20275
uniprot id: A0A7I7JUR4
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

2492438:G6N19 RS14905
gene id: 2492438:G6N19_RS14905
uniprot id: A0A7I7JQ02
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

2492438:G6N19 RS15915
gene id: 2492438:G6N19_RS15915
uniprot id: A0A7I7JSS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2492438:G6N19 RS16905
gene id: 2492438:G6N19_RS16905
uniprot id: A0A7I7JSL5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

2492438:G6N19 RS17995
gene id: 2492438:G6N19_RS17995
uniprot id: A0A7I7JT79
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

2492438:G6N19 RS06780
gene id: 2492438:G6N19_RS06780
uniprot id: A0A7I7JMR5
names: Cofactor
messages: Can also use Mn(2+) ion.

2492438:G6N19 RS02170
gene id: 2492438:G6N19_RS02170
uniprot id: A0A7I7JJG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2492438:G6N19 RS20670
gene id: 2492438:G6N19_RS20670
uniprot id: A0A7I7JT89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EspG family.
messages: Cytoplasm

2492438:G6N19 RS14730
gene id: 2492438:G6N19_RS14730
uniprot id: A0A7I7JPR6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2492438:G6N19 RS16995
gene id: 2492438:G6N19_RS16995
uniprot id: A0A7I7JR19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

2492438:G6N19 RS20680
gene id: 2492438:G6N19_RS20680
uniprot id: A0A7I7JIK5
names: Similarity
messages: Belongs to the WXG100 family.

2492438:G6N19 RS06790
gene id: 2492438:G6N19_RS06790
uniprot id: A0A7I7JM14
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

2492438:G6N19 RS12360
gene id: 2492438:G6N19_RS12360
uniprot id: A0A7I7JQW9
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

2492438:G6N19 RS03165
gene id: 2492438:G6N19_RS03165
uniprot id: A0A7I7JII8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

2492438:G6N19 RS09040
gene id: 2492438:G6N19_RS09040
uniprot id: A0A7I7JLE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CwsA family.
messages: Cell membrane
messages: Required for regulated cell division, cell wall synthesis and the maintenance of cell shape.

2492438:G6N19 RS06505
gene id: 2492438:G6N19_RS06505
uniprot id: A0A7I7JLF0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2492438:G6N19 RS13565
gene id: 2492438:G6N19_RS13565
uniprot id: A0A7I7JP34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2492438:G6N19 RS20210
gene id: 2492438:G6N19_RS20210
uniprot id: A0A7I7JUR3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

2492438:G6N19 RS20465
gene id: 2492438:G6N19_RS20465
uniprot id: A0A7I7JTD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

2492438:G6N19 RS04430
gene id: 2492438:G6N19_RS04430
uniprot id: A0A7I7JK38
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

2492438:G6N19 RS17325
gene id: 2492438:G6N19_RS17325
uniprot id: A0A7I7JT16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

2492438:G6N19 RS20565
gene id: 2492438:G6N19_RS20565
uniprot id: A0A7I7JUZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0749 family.
messages: Membrane

2492438:G6N19 RS17060
gene id: 2492438:G6N19_RS17060
uniprot id: A0A7I7JSZ1
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

2492438:G6N19 RS17585
gene id: 2492438:G6N19_RS17585
uniprot id: A0A7I7JRK6
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

2492438:G6N19 RS20135
gene id: 2492438:G6N19_RS20135
uniprot id: A0A7I7JSX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

2492438:G6N19 RS09300
gene id: 2492438:G6N19_RS09300
uniprot id: A0A7I7JNG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

2492438:G6N19 RS16540
gene id: 2492438:G6N19_RS16540
uniprot id: A0A7I7JQU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

2492438:G6N19 RS02825
gene id: 2492438:G6N19_RS02825
uniprot id: A0A7I7JHS6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

2492438:G6N19 RS04855
gene id: 2492438:G6N19_RS04855
uniprot id: A0A7I7JLM9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

2492438:G6N19 RS17290
gene id: 2492438:G6N19_RS17290
uniprot id: A0A7I7JR81
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

2492438:G6N19 RS01265
gene id: 2492438:G6N19_RS01265
uniprot id: A0A7I7JI72
names: Similarity
messages: Belongs to the TPP enzyme family.

2492438:G6N19 RS03095
gene id: 2492438:G6N19_RS03095
uniprot id: A0A7I7JJL8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

2492438:G6N19 RS16630
gene id: 2492438:G6N19_RS16630
uniprot id: A0A7I7JQW0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

2492438:G6N19 RS17005
gene id: 2492438:G6N19_RS17005
uniprot id: A0A7I7JSN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

2492438:G6N19 RS17110
gene id: 2492438:G6N19_RS17110
uniprot id: A0A7I7JT00
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS10045
gene id: 2492438:G6N19_RS10045
uniprot id: A0A7I7JM16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

2492438:G6N19 RS19225
gene id: 2492438:G6N19_RS19225
uniprot id: A0A7I7JSG4
names: Similarity
messages: Belongs to the asparaginase 1 family.

2492438:G6N19 RS13635
gene id: 2492438:G6N19_RS13635
uniprot id: A0A7I7JQP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2492438:G6N19 RS17135
gene id: 2492438:G6N19_RS17135
uniprot id: A0A7I7JRB9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS01065
gene id: 2492438:G6N19_RS01065
uniprot id: A0A7I7JI31
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

2492438:G6N19 RS09605
gene id: 2492438:G6N19_RS09605
uniprot id: A0A7I7JLT3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2492438:G6N19 RS20505
gene id: 2492438:G6N19_RS20505
uniprot id: A0A7I7JVC0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2492438:G6N19 RS04410
gene id: 2492438:G6N19_RS04410
uniprot id: A0A7I7JKI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

2492438:G6N19 RS05660
gene id: 2492438:G6N19_RS05660
uniprot id: A0A7I7JJH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2492438:G6N19 RS13070
gene id: 2492438:G6N19_RS13070
uniprot id: A0A7I7JNS9
names: Similarity
messages: Belongs to the cytochrome P450 family.

2492438:G6N19 RS03565
gene id: 2492438:G6N19_RS03565
uniprot id: A0A7I7JI81
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

2492438:G6N19 RS03625
gene id: 2492438:G6N19_RS03625
uniprot id: A0A7I7JI86
names: Similarity
messages: Belongs to the cytochrome P450 family.

2492438:G6N19 RS04175
gene id: 2492438:G6N19_RS04175
uniprot id: A0A7I7JIK5
names: Similarity
messages: Belongs to the WXG100 family.

2492438:G6N19 RS17450
gene id: 2492438:G6N19_RS17450
uniprot id: A0A7I7JRH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

2492438:G6N19 RS19695
gene id: 2492438:G6N19_RS19695
uniprot id: A0A7I7JTX0
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS01580
gene id: 2492438:G6N19_RS01580
uniprot id: A0A7I7JHP8
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

2492438:G6N19 RS06550
gene id: 2492438:G6N19_RS06550
uniprot id: A0A7I7JK34
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

2492438:G6N19 RS16285
gene id: 2492438:G6N19_RS16285
uniprot id: A0A7I7JQM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

2492438:G6N19 RS14220
gene id: 2492438:G6N19_RS14220
uniprot id: A0A7I7JPS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

2492438:G6N19 RS18285
gene id: 2492438:G6N19_RS18285
uniprot id: A0A7I7JRS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

2492438:G6N19 RS02015
gene id: 2492438:G6N19_RS02015
uniprot id: A0A7I7JHZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

2492438:G6N19 RS11430
gene id: 2492438:G6N19_RS11430
uniprot id: A0A7I7JPF6
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

2492438:G6N19 RS12390
gene id: 2492438:G6N19_RS12390
uniprot id: A0A7I7JPS0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

2492438:G6N19 RS16085
gene id: 2492438:G6N19_RS16085
uniprot id: A0A7I7JQI1
names: Similarity
messages: Belongs to the CdaR family.

2492438:G6N19 RS17730
gene id: 2492438:G6N19_RS17730
uniprot id: A0A7I7JRM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2492438:G6N19 RS19655
gene id: 2492438:G6N19_RS19655
uniprot id: A0A7I7JST9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS13320
gene id: 2492438:G6N19_RS13320
uniprot id: A0A7I7JP41
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2492438:G6N19 RS05580
gene id: 2492438:G6N19_RS05580
uniprot id: A0A7I7JLD3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2492438:G6N19 RS19165
gene id: 2492438:G6N19_RS19165
uniprot id: A0A7I7JSM0
names: Similarity
messages: Belongs to the cytochrome P450 family.

2492438:G6N19 RS14275
gene id: 2492438:G6N19_RS14275
uniprot id: A0A7I7JR93
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS17440
gene id: 2492438:G6N19_RS17440
uniprot id: A0A7I7JSL9
names: Similarity
messages: Belongs to the ribF family.

2492438:G6N19 RS17140
gene id: 2492438:G6N19_RS17140
uniprot id: A0A7I7JR49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

2492438:G6N19 RS18185
gene id: 2492438:G6N19_RS18185
uniprot id: A0A7I7JTG1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2492438:G6N19 RS09160
gene id: 2492438:G6N19_RS09160
uniprot id: A0A7I7JLG4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2492438:G6N19 RS00215
gene id: 2492438:G6N19_RS00215
uniprot id: A0A7I7JG90
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2492438:G6N19 RS18505
gene id: 2492438:G6N19_RS18505
uniprot id: A0A7I7JTI6
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

2492438:G6N19 RS01665
gene id: 2492438:G6N19_RS01665
uniprot id: A0A7I7JIW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

2492438:G6N19 RS08225
gene id: 2492438:G6N19_RS08225
uniprot id: A0A7I7JNH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

2492438:G6N19 RS09075
gene id: 2492438:G6N19_RS09075
uniprot id: A0A7I7JLS0
names: Similarity
messages: Belongs to the UPF0232 family.

2492438:G6N19 RS13570
gene id: 2492438:G6N19_RS13570
uniprot id: A0A7I7JP92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2492438:G6N19 RS18830
gene id: 2492438:G6N19_RS18830
uniprot id: A0A7I7JS65
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

2492438:G6N19 RS11045
gene id: 2492438:G6N19_RS11045
uniprot id: A0A7I7JPI2
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS04705
gene id: 2492438:G6N19_RS04705
uniprot id: A0A7I7JLK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

2492438:G6N19 RS06985
gene id: 2492438:G6N19_RS06985
uniprot id: A0A7I7JM46
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2492438:G6N19 RS20970
gene id: 2492438:G6N19_RS20970
uniprot id: A0A7I7JG71
names: Similarity
messages: Belongs to the UPF0434 family.

2492438:G6N19 RS19580
gene id: 2492438:G6N19_RS19580
uniprot id: A0A7I7JSP5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2492438:G6N19 RS06280
gene id: 2492438:G6N19_RS06280
uniprot id: A0A7I7JME8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

2492438:G6N19 RS02095
gene id: 2492438:G6N19_RS02095
uniprot id: A0A7I7JHF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2492438:G6N19 RS10920
gene id: 2492438:G6N19_RS10920
uniprot id: A0A7I7JMT0
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

2492438:G6N19 RS05675
gene id: 2492438:G6N19_RS05675
uniprot id: A0A7I7JKV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2492438:G6N19 RS10925
gene id: 2492438:G6N19_RS10925
uniprot id: A0A7I7JPH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

2492438:G6N19 RS04190
gene id: 2492438:G6N19_RS04190
uniprot id: A0A7I7JJ22
names: Similarity
messages: Belongs to the mycobacterial PPE family.

2492438:G6N19 RS00585
gene id: 2492438:G6N19_RS00585
uniprot id: A0A7I7JI89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

2492438:G6N19 RS20665
gene id: 2492438:G6N19_RS20665
uniprot id: A0A7I7JTB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccD/Snm4 family.
messages: Membrane

2492438:G6N19 RS20495
gene id: 2492438:G6N19_RS20495
uniprot id: A0A7I7JTB5
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS02295
gene id: 2492438:G6N19_RS02295
uniprot id: A0A7I7JJG4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

2492438:G6N19 RS06815
gene id: 2492438:G6N19_RS06815
uniprot id: A0A7I7JLT9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

2492438:G6N19 RS17445
gene id: 2492438:G6N19_RS17445
uniprot id: A0A7I7JSX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2492438:G6N19 RS14460
gene id: 2492438:G6N19_RS14460
uniprot id: A0A7I7JRF7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS19475
gene id: 2492438:G6N19_RS19475
uniprot id: A0A7I7JSL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

2492438:G6N19 RS01605
gene id: 2492438:G6N19_RS01605
uniprot id: A0A7I7JH59
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

2492438:G6N19 RS13755
gene id: 2492438:G6N19_RS13755
uniprot id: A0A7I7JR16
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

2492438:G6N19 RS06130
gene id: 2492438:G6N19_RS06130
uniprot id: A0A7I7JLR4
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS02120
gene id: 2492438:G6N19_RS02120
uniprot id: A0A7I7JJF3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

2492438:G6N19 RS03430
gene id: 2492438:G6N19_RS03430
uniprot id: A0A7I7JJE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

2492438:G6N19 RS05070
gene id: 2492438:G6N19_RS05070
uniprot id: A0A7I7JKY1
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

2492438:G6N19 RS12530
gene id: 2492438:G6N19_RS12530
uniprot id: A0A7I7JNP5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2492438:G6N19 RS13840
gene id: 2492438:G6N19_RS13840
uniprot id: A0A7I7JQK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2492438:G6N19 RS18245
gene id: 2492438:G6N19_RS18245
uniprot id: A0A7I7JRQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

2492438:G6N19 RS07090
gene id: 2492438:G6N19_RS07090
uniprot id: A0A7I7JKB6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

2492438:G6N19 RS13655
gene id: 2492438:G6N19_RS13655
uniprot id: A0A7I7JPG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

2492438:G6N19 RS20900
gene id: 2492438:G6N19_RS20900
uniprot id: A0A7I7JTK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS16710
gene id: 2492438:G6N19_RS16710
uniprot id: A0A7I7JR28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial histone-like protein family. Long actinobacterial subfamily.
messages: nucleoid

2492438:G6N19 RS06145
gene id: 2492438:G6N19_RS06145
uniprot id: A0A7I7JLL5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

2492438:G6N19 RS18895
gene id: 2492438:G6N19_RS18895
uniprot id: A0A7I7JTQ9
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

2492438:G6N19 RS20905
gene id: 2492438:G6N19_RS20905
uniprot id: A0A7I7JV55
names: Similarity
messages: Belongs to the TlyA family.

2492438:G6N19 RS18230
gene id: 2492438:G6N19_RS18230
uniprot id: A0A7I7JS38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

2492438:G6N19 RS08330
gene id: 2492438:G6N19_RS08330
uniprot id: A0A7I7JNJ2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2492438:G6N19 RS09305
gene id: 2492438:G6N19_RS09305
uniprot id: A0A7I7JLJ1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

2492438:G6N19 RS18365
gene id: 2492438:G6N19_RS18365
uniprot id: A0A7I7JTN9
names: Similarity
messages: Belongs to the WXG100 family.

2492438:G6N19 RS08290
gene id: 2492438:G6N19_RS08290
uniprot id: A0A7I7JMW1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS18120
gene id: 2492438:G6N19_RS18120
uniprot id: A0A7I7JRV0
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

2492438:G6N19 RS00440
gene id: 2492438:G6N19_RS00440
uniprot id: A0A7I7JIF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

2492438:G6N19 RS19015
gene id: 2492438:G6N19_RS19015
uniprot id: A0A7I7JSJ0
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS20040
gene id: 2492438:G6N19_RS20040
uniprot id: A0A7I7JSV6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

2492438:G6N19 RS18730
gene id: 2492438:G6N19_RS18730
uniprot id: A0A7I7JS43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

2492438:G6N19 RS20200
gene id: 2492438:G6N19_RS20200
uniprot id: A0A7I7JUI5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

2492438:G6N19 RS18595
gene id: 2492438:G6N19_RS18595
uniprot id: A0A7I7JTA2
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

2492438:G6N19 RS13575
gene id: 2492438:G6N19_RS13575
uniprot id: A0A7I7JP26
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2492438:G6N19 RS18020
gene id: 2492438:G6N19_RS18020
uniprot id: A0A7I7JTD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

2492438:G6N19 RS15520
gene id: 2492438:G6N19_RS15520
uniprot id: A0A7I7JS10
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

2492438:G6N19 RS01450
gene id: 2492438:G6N19_RS01450
uniprot id: A0A7I7JH23
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

2492438:G6N19 RS05855
gene id: 2492438:G6N19_RS05855
uniprot id: A0A7I7JJZ2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2492438:G6N19 RS20615
gene id: 2492438:G6N19_RS20615
uniprot id: A0A7I7JT97
names: Similarity
messages: Belongs to the mycobacterial PPE family.

2492438:G6N19 RS04540
gene id: 2492438:G6N19_RS04540
uniprot id: A0A7I7JKD7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2492438:G6N19 RS16500
gene id: 2492438:G6N19_RS16500
uniprot id: A0A7I7JSD0
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

2492438:G6N19 RS11470
gene id: 2492438:G6N19_RS11470
uniprot id: A0A7I7JMW4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

2492438:G6N19 RS00460
gene id: 2492438:G6N19_RS00460
uniprot id: A0A7I7JGH2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2492438:G6N19 RS14070
gene id: 2492438:G6N19_RS14070
uniprot id: A0A7I7JPQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

2492438:G6N19 RS01955
gene id: 2492438:G6N19_RS01955
uniprot id: A0A7I7JIN4
names: Similarity
messages: Belongs to the MmpS family.

2492438:G6N19 RS16400
gene id: 2492438:G6N19_RS16400
uniprot id: A0A7I7JSB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

2492438:G6N19 RS20060
gene id: 2492438:G6N19_RS20060
uniprot id: A0A7I7JUN6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2492438:G6N19 RS11560
gene id: 2492438:G6N19_RS11560
uniprot id: A0A7I7JMZ2
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

2492438:G6N19 RS01675
gene id: 2492438:G6N19_RS01675
uniprot id: A0A7I7JJ64
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

2492438:G6N19 RS04670
gene id: 2492438:G6N19_RS04670
uniprot id: A0A7I7JIW0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

2492438:G6N19 RS19930
gene id: 2492438:G6N19_RS19930
uniprot id: A0A7I7JT19
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

2492438:G6N19 RS07145
gene id: 2492438:G6N19_RS07145
uniprot id: A0A7I7JKD6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2492438:G6N19 RS17455
gene id: 2492438:G6N19_RS17455
uniprot id: A0A7I7JT61
names: Similarity
messages: Belongs to the peptidase M16 family.

2492438:G6N19 RS08295
gene id: 2492438:G6N19_RS08295
uniprot id: A0A7I7JL00
names: Cofactor
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.
messages: Binds 1 heme group per subunit.

2492438:G6N19 RS12795
gene id: 2492438:G6N19_RS12795
uniprot id: A0A7I7JNV1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2492438:G6N19 RS15905
gene id: 2492438:G6N19_RS15905
uniprot id: A0A7I7JQK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2492438:G6N19 RS11105
gene id: 2492438:G6N19_RS11105
uniprot id: A0A7I7JMP2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

2492438:G6N19 RS17320
gene id: 2492438:G6N19_RS17320
uniprot id: A0A7I7JRN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

2492438:G6N19 RS17190
gene id: 2492438:G6N19_RS17190
uniprot id: A0A7I7JR63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

2492438:G6N19 RS12435
gene id: 2492438:G6N19_RS12435
uniprot id: A0A7I7JNG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

2492438:G6N19 RS16655
gene id: 2492438:G6N19_RS16655
uniprot id: A0A7I7JR18
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

2492438:G6N19 RS19510
gene id: 2492438:G6N19_RS19510
uniprot id: A0A7I7JUR9
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

2492438:G6N19 RS13035
gene id: 2492438:G6N19_RS13035
uniprot id: A0A7I7JQ41
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2492438:G6N19 RS06600
gene id: 2492438:G6N19_RS06600
uniprot id: A0A7I7JK35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

2492438:G6N19 RS16505
gene id: 2492438:G6N19_RS16505
uniprot id: A0A7I7JQY0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

2492438:G6N19 RS00345
gene id: 2492438:G6N19_RS00345
uniprot id: A0A7I7JJ53
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

2492438:G6N19 RS10420
gene id: 2492438:G6N19_RS10420
uniprot id: A0A7I7JPR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

2492438:G6N19 RS20330
gene id: 2492438:G6N19_RS20330
uniprot id: A0A7I7JT39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

2492438:G6N19 RS20280
gene id: 2492438:G6N19_RS20280
uniprot id: A0A7I7JT29
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS13855
gene id: 2492438:G6N19_RS13855
uniprot id: A0A7I7JPE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2492438:G6N19 RS19675
gene id: 2492438:G6N19_RS19675
uniprot id: A0A7I7JUC9
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS18225
gene id: 2492438:G6N19_RS18225
uniprot id: A0A7I7JU23
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

2492438:G6N19 RS03480
gene id: 2492438:G6N19_RS03480
uniprot id: A0A7I7JJF5
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

2492438:G6N19 RS10880
gene id: 2492438:G6N19_RS10880
uniprot id: A0A7I7JQ23
names: Similarity
messages: Belongs to the CFA/CMAS family.

2492438:G6N19 RS20030
gene id: 2492438:G6N19_RS20030
uniprot id: A0A7I7JSY4
names: Similarity
messages: Belongs to the CFA/CMAS family.

2492438:G6N19 RS19725
gene id: 2492438:G6N19_RS19725
uniprot id: A0A7I7JUE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2492438:G6N19 RS10605
gene id: 2492438:G6N19_RS10605
uniprot id: A0A7I7JPA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

2492438:G6N19 RS05230
gene id: 2492438:G6N19_RS05230
uniprot id: A0A7I7JJ75
names: Similarity
messages: Belongs to the MoaD family.

2492438:G6N19 RS17580
gene id: 2492438:G6N19_RS17580
uniprot id: A0A7I7JRC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

2492438:G6N19 RS08345
gene id: 2492438:G6N19_RS08345
uniprot id: A0A7I7JL12
names: Similarity
messages: Belongs to the pirin family.

2492438:G6N19 RS12350
gene id: 2492438:G6N19_RS12350
uniprot id: A0A7I7JNM0
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

2492438:G6N19 RS17615
gene id: 2492438:G6N19_RS17615
uniprot id: A0A7I7JRV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

2492438:G6N19 RS12895
gene id: 2492438:G6N19_RS12895
uniprot id: A0A7I7JNW8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2492438:G6N19 RS07140
gene id: 2492438:G6N19_RS07140
uniprot id: A0A7I7JKC4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS20205
gene id: 2492438:G6N19_RS20205
uniprot id: A0A7I7JT54
names: Similarity
messages: Belongs to the UPF0045 family.

2492438:G6N19 RS04565
gene id: 2492438:G6N19_RS04565
uniprot id: A0A7I7JKM4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2492438:G6N19 RS12325
gene id: 2492438:G6N19_RS12325
uniprot id: A0A7I7JNE7
names: Similarity
messages: Belongs to the GARS family.

2492438:G6N19 RS13870
gene id: 2492438:G6N19_RS13870
uniprot id: A0A7I7JPL0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2492438:G6N19 RS15180
gene id: 2492438:G6N19_RS15180
uniprot id: A0A7I7JQ03
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2-dependent reduction of dehydro-F420-0 to form F420-0.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: In the N-terminal section; belongs to the CofE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monovalent cation. The ion could be potassium.

2492438:G6N19 RS15165
gene id: 2492438:G6N19_RS15165
uniprot id: A0A7I7JRT9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

2492438:G6N19 RS04245
gene id: 2492438:G6N19_RS04245
uniprot id: A0A7I7JKM7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

2492438:G6N19 RS09090
gene id: 2492438:G6N19_RS09090
uniprot id: A0A7I7JLT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

2492438:G6N19 RS13275
gene id: 2492438:G6N19_RS13275
uniprot id: A0A7I7JNW9
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

2492438:G6N19 RS17020
gene id: 2492438:G6N19_RS17020
uniprot id: A0A7I7JRH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

2492438:G6N19 RS18975
gene id: 2492438:G6N19_RS18975
uniprot id: A0A7I7JSB1
names: Similarity
messages: Belongs to the peptidase C40 family.

2492438:G6N19 RS12625
gene id: 2492438:G6N19_RS12625
uniprot id: A0A7I7JNR7
names: Subcellular Location Annotation
messages: Cell membrane

2492438:G6N19 RS14215
gene id: 2492438:G6N19_RS14215
uniprot id: A0A7I7JRV2
names: Similarity
messages: Belongs to the universal stress protein A family.

2492438:G6N19 RS12045
gene id: 2492438:G6N19_RS12045
uniprot id: A0A7I7JNH1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2492438:G6N19 RS01435
gene id: 2492438:G6N19_RS01435
uniprot id: A0A7I7JJS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

2492438:G6N19 RS14525
gene id: 2492438:G6N19_RS14525
uniprot id: A0A7I7JRE2
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

2492438:G6N19 RS16485
gene id: 2492438:G6N19_RS16485
uniprot id: A0A7I7JQZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS00210
gene id: 2492438:G6N19_RS00210
uniprot id: A0A7I7JGC3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2492438:G6N19 RS08795
gene id: 2492438:G6N19_RS08795
uniprot id: A0A7I7JLD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

2492438:G6N19 RS05265
gene id: 2492438:G6N19_RS05265
uniprot id: A0A7I7JJN9
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

2492438:G6N19 RS16575
gene id: 2492438:G6N19_RS16575
uniprot id: A0A7I7JSM2
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

2492438:G6N19 RS17785
gene id: 2492438:G6N19_RS17785
uniprot id: A0A7I7JRH8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2492438:G6N19 RS18860
gene id: 2492438:G6N19_RS18860
uniprot id: A0A7I7JUE7
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS15185
gene id: 2492438:G6N19_RS15185
uniprot id: A0A7I7JRF1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS02050
gene id: 2492438:G6N19_RS02050
uniprot id: A0A7I7JHH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

2492438:G6N19 RS19045
gene id: 2492438:G6N19_RS19045
uniprot id: A0A7I7JTT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates.
messages: Heterodimer of an alpha and a beta chain.

2492438:G6N19 RS07310
gene id: 2492438:G6N19_RS07310
uniprot id: A0A7I7JM41
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS19030
gene id: 2492438:G6N19_RS19030
uniprot id: A0A7I7JSA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

2492438:G6N19 RS15285
gene id: 2492438:G6N19_RS15285
uniprot id: A0A7I7JRH1
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

2492438:G6N19 RS09310
gene id: 2492438:G6N19_RS09310
uniprot id: A0A7I7JLJ0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

2492438:G6N19 RS14315
gene id: 2492438:G6N19_RS14315
uniprot id: A0A7I7JRW6
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

2492438:G6N19 RS08015
gene id: 2492438:G6N19_RS08015
uniprot id: A0A7I7JL76
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

2492438:G6N19 RS00140
gene id: 2492438:G6N19_RS00140
uniprot id: A0A7I7JJ13
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS08000
gene id: 2492438:G6N19_RS08000
uniprot id: A0A7I7JKX3
names: Similarity
messages: Belongs to the WrbA family.

2492438:G6N19 RS03120
gene id: 2492438:G6N19_RS03120
uniprot id: A0A7I7JJT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2492438:G6N19 RS01160
gene id: 2492438:G6N19_RS01160
uniprot id: A0A7I7JGV0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

2492438:G6N19 RS20455
gene id: 2492438:G6N19_RS20455
uniprot id: A0A7I7JUW9
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

2492438:G6N19 RS01310
gene id: 2492438:G6N19_RS01310
uniprot id: A0A7I7JH35
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

2492438:G6N19 RS00880
gene id: 2492438:G6N19_RS00880
uniprot id: A0A7I7JIE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2492438:G6N19 RS16650
gene id: 2492438:G6N19_RS16650
uniprot id: A0A7I7JSH2
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

2492438:G6N19 RS18260
gene id: 2492438:G6N19_RS18260
uniprot id: A0A7I7JS26
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

2492438:G6N19 RS18265
gene id: 2492438:G6N19_RS18265
uniprot id: A0A7I7JTL9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

2492438:G6N19 RS18500
gene id: 2492438:G6N19_RS18500
uniprot id: A0A7I7JT82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

2492438:G6N19 RS07260
gene id: 2492438:G6N19_RS07260
uniprot id: A0A7I7JM25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

2492438:G6N19 RS09020
gene id: 2492438:G6N19_RS09020
uniprot id: A0A7I7JNC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0749 family.
messages: Membrane

2492438:G6N19 RS02370
gene id: 2492438:G6N19_RS02370
uniprot id: A0A7I7JIV9
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

2492438:G6N19 RS16265
gene id: 2492438:G6N19_RS16265
uniprot id: A0A7I7JSH6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2492438:G6N19 RS11100
gene id: 2492438:G6N19_RS11100
uniprot id: A0A7I7JMP4
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme modulates the balance between respiration and glycolysis, and contributes to redox homeostasis. Probably eliminates toxic levels of Cys (which can induce oxidative stress).
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

2492438:G6N19 RS02615
gene id: 2492438:G6N19_RS02615
uniprot id: A0A7I7JHN8
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

2492438:G6N19 RS08595
gene id: 2492438:G6N19_RS08595
uniprot id: A0A7I7JMJ0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2492438:G6N19 RS02160
gene id: 2492438:G6N19_RS02160
uniprot id: A0A7I7JJ47
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2492438:G6N19 RS01190
gene id: 2492438:G6N19_RS01190
uniprot id: A0A7I7JHF7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

2492438:G6N19 RS12425
gene id: 2492438:G6N19_RS12425
uniprot id: A0A7I7JNG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

2492438:G6N19 RS06960
gene id: 2492438:G6N19_RS06960
uniprot id: A0A7I7JLW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

2492438:G6N19 RS09205
gene id: 2492438:G6N19_RS09205
uniprot id: A0A7I7JLH3
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

2492438:G6N19 RS02720
gene id: 2492438:G6N19_RS02720
uniprot id: A0A7I7JJM7
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

2492438:G6N19 RS15150
gene id: 2492438:G6N19_RS15150
uniprot id: A0A7I7JRV3
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

2492438:G6N19 RS14230
gene id: 2492438:G6N19_RS14230
uniprot id: A0A7I7JPG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

2492438:G6N19 RS20570
gene id: 2492438:G6N19_RS20570
uniprot id: A0A7I7JT84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

2492438:G6N19 RS02565
gene id: 2492438:G6N19_RS02565
uniprot id: A0A7I7JJK2
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS03570
gene id: 2492438:G6N19_RS03570
uniprot id: A0A7I7JI91
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2492438:G6N19 RS17270
gene id: 2492438:G6N19_RS17270
uniprot id: A0A7I7JRL9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

2492438:G6N19 RS12690
gene id: 2492438:G6N19_RS12690
uniprot id: A0A7I7JQ66
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2492438:G6N19 RS00280
gene id: 2492438:G6N19_RS00280
uniprot id: A0A7I7JI25
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

2492438:G6N19 RS13675
gene id: 2492438:G6N19_RS13675
uniprot id: A0A7I7JP48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2492438:G6N19 RS13630
gene id: 2492438:G6N19_RS13630
uniprot id: A0A7I7JQG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2492438:G6N19 RS13670
gene id: 2492438:G6N19_RS13670
uniprot id: A0A7I7JPB3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2492438:G6N19 RS04620
gene id: 2492438:G6N19_RS04620
uniprot id: A0A7I7JIV0
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS15380
gene id: 2492438:G6N19_RS15380
uniprot id: A0A7I7JQ40
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

2492438:G6N19 RS00640
gene id: 2492438:G6N19_RS00640
uniprot id: A0A7I7JH39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

2492438:G6N19 RS01590
gene id: 2492438:G6N19_RS01590
uniprot id: A0A7I7JJU7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

2492438:G6N19 RS16980
gene id: 2492438:G6N19_RS16980
uniprot id: A0A7I7JSU7
names: Similarity
messages: Belongs to the peptidase S11 family.

2492438:G6N19 RS05670
gene id: 2492438:G6N19_RS05670
uniprot id: A0A7I7JJI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2492438:G6N19 RS19720
gene id: 2492438:G6N19_RS19720
uniprot id: A0A7I7JSY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2492438:G6N19 RS16395
gene id: 2492438:G6N19_RS16395
uniprot id: A0A7I7JS23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

2492438:G6N19 RS14495
gene id: 2492438:G6N19_RS14495
uniprot id: A0A7I7JQZ1
names: Similarity
messages: Belongs to the peptidase S11 family.

2492438:G6N19 RS07295
gene id: 2492438:G6N19_RS07295
uniprot id: A0A7I7JKG5
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS00670
gene id: 2492438:G6N19_RS00670
uniprot id: A0A7I7JGI5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

2492438:G6N19 RS03770
gene id: 2492438:G6N19_RS03770
uniprot id: A0A7I7JIC6
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS01100
gene id: 2492438:G6N19_RS01100
uniprot id: A0A7I7JGV8
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

2492438:G6N19 RS12715
gene id: 2492438:G6N19_RS12715
uniprot id: A0A7I7JQF0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2492438:G6N19 RS05130
gene id: 2492438:G6N19_RS05130
uniprot id: A0A7I7JJ54
names: Similarity
messages: Belongs to the citrate synthase family.

2492438:G6N19 RS17000
gene id: 2492438:G6N19_RS17000
uniprot id: A0A7I7JSE4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

2492438:G6N19 RS03170
gene id: 2492438:G6N19_RS03170
uniprot id: A0A7I7JJU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2492438:G6N19 RS05515
gene id: 2492438:G6N19_RS05515
uniprot id: A0A7I7JKR1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

2492438:G6N19 RS01070
gene id: 2492438:G6N19_RS01070
uniprot id: A0A7I7JII5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

2492438:G6N19 RS20220
gene id: 2492438:G6N19_RS20220
uniprot id: A0A7I7JT81
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

2492438:G6N19 RS11170
gene id: 2492438:G6N19_RS11170
uniprot id: A0A7I7JP40
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS12660
gene id: 2492438:G6N19_RS12660
uniprot id: A0A7I7JNX6
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

2492438:G6N19 RS18445
gene id: 2492438:G6N19_RS18445
uniprot id: A0A7I7JRW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

2492438:G6N19 RS05430
gene id: 2492438:G6N19_RS05430
uniprot id: A0A7I7JL99
names: Similarity
messages: Belongs to the TPP enzyme family.

2492438:G6N19 RS13930
gene id: 2492438:G6N19_RS13930
uniprot id: A0A7I7JPB1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2492438:G6N19 RS17195
gene id: 2492438:G6N19_RS17195
uniprot id: A0A7I7JSH1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

2492438:G6N19 RS02770
gene id: 2492438:G6N19_RS02770
uniprot id: A0A7I7JJN7
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS16705
gene id: 2492438:G6N19_RS16705
uniprot id: A0A7I7JSI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

2492438:G6N19 RS04035
gene id: 2492438:G6N19_RS04035
uniprot id: A0A7I7JIZ3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

2492438:G6N19 RS06685
gene id: 2492438:G6N19_RS06685
uniprot id: A0A7I7JKJ2
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

2492438:G6N19 RS17265
gene id: 2492438:G6N19_RS17265
uniprot id: A0A7I7JTJ9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2492438:G6N19 RS04005
gene id: 2492438:G6N19_RS04005
uniprot id: A0A7I7JKA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

2492438:G6N19 RS03550
gene id: 2492438:G6N19_RS03550
uniprot id: A0A7I7JKW0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2492438:G6N19 RS18535
gene id: 2492438:G6N19_RS18535
uniprot id: A0A7I7JS07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2492438:G6N19 RS15640
gene id: 2492438:G6N19_RS15640
uniprot id: A0A7I7JRP6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

2492438:G6N19 RS08275
gene id: 2492438:G6N19_RS08275
uniprot id: A0A7I7JMX1
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS16260
gene id: 2492438:G6N19_RS16260
uniprot id: A0A7I7JQS4
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS15020
gene id: 2492438:G6N19_RS15020
uniprot id: A0A7I7JPW9
names: Similarity
messages: Belongs to the SufE family.

2492438:G6N19 RS00910
gene id: 2492438:G6N19_RS00910
uniprot id: A0A7I7JGR9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

2492438:G6N19 RS20115
gene id: 2492438:G6N19_RS20115
uniprot id: A0A7I7JV38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

2492438:G6N19 RS19405
gene id: 2492438:G6N19_RS19405
uniprot id: A0A7I7JUA1
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

2492438:G6N19 RS20490
gene id: 2492438:G6N19_RS20490
uniprot id: A0A7I7JUP5
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS10900
gene id: 2492438:G6N19_RS10900
uniprot id: A0A7I7JMK2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

2492438:G6N19 RS19670
gene id: 2492438:G6N19_RS19670
uniprot id: A0A7I7JSX3
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

2492438:G6N19 RS00110
gene id: 2492438:G6N19_RS00110
uniprot id: A0A7I7JG71
names: Similarity
messages: Belongs to the UPF0434 family.

2492438:G6N19 RS18615
gene id: 2492438:G6N19_RS18615
uniprot id: A0A7I7JUA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2492438:G6N19 RS00090
gene id: 2492438:G6N19_RS00090
uniprot id: A0A7I7JJ04
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

2492438:G6N19 RS00595
gene id: 2492438:G6N19_RS00595
uniprot id: A0A7I7JII2
names: Similarity
messages: Belongs to the YggT family.

2492438:G6N19 RS00295
gene id: 2492438:G6N19_RS00295
uniprot id: A0A7I7JJ44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the UPF0157 (GrpB) family.
messages: In the N-terminal section; belongs to the CoaE family.

2492438:G6N19 RS12815
gene id: 2492438:G6N19_RS12815
uniprot id: A0A7I7JQG8
names: Similarity
messages: Belongs to the HIBADH-related family.

2492438:G6N19 RS07875
gene id: 2492438:G6N19_RS07875
uniprot id: A0A7I7JL72
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

2492438:G6N19 RS11555
gene id: 2492438:G6N19_RS11555
uniprot id: A0A7I7JMZ8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

2492438:G6N19 RS15215
gene id: 2492438:G6N19_RS15215
uniprot id: A0A7I7JRW0
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

2492438:G6N19 RS17555
gene id: 2492438:G6N19_RS17555
uniprot id: A0A7I7JRJ1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2492438:G6N19 RS17280
gene id: 2492438:G6N19_RS17280
uniprot id: A0A7I7JR70
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

2492438:G6N19 RS12630
gene id: 2492438:G6N19_RS12630
uniprot id: A0A7I7JNJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

2492438:G6N19 RS15560
gene id: 2492438:G6N19_RS15560
uniprot id: A0A7I7JSK3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2492438:G6N19 RS17305
gene id: 2492438:G6N19_RS17305
uniprot id: A0A7I7JRE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

2492438:G6N19 RS00170
gene id: 2492438:G6N19_RS00170
uniprot id: A0A7I7JHJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

2492438:G6N19 RS05435
gene id: 2492438:G6N19_RS05435
uniprot id: A0A7I7JLY3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2492438:G6N19 RS08280
gene id: 2492438:G6N19_RS08280
uniprot id: A0A7I7JNI5
names: Similarity
messages: Belongs to the CsoR family.

2492438:G6N19 RS18450
gene id: 2492438:G6N19_RS18450
uniprot id: A0A7I7JT71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

2492438:G6N19 RS08915
gene id: 2492438:G6N19_RS08915
uniprot id: A0A7I7JNA3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2492438:G6N19 RS04495
gene id: 2492438:G6N19_RS04495
uniprot id: A0A7I7JJ83
names: Similarity
messages: Belongs to the UDPGP type 2 family.

2492438:G6N19 RS07370
gene id: 2492438:G6N19_RS07370
uniprot id: A0A7I7JMG5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

2492438:G6N19 RS10955
gene id: 2492438:G6N19_RS10955
uniprot id: A0A7I7JMK8
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

2492438:G6N19 RS11780
gene id: 2492438:G6N19_RS11780
uniprot id: A0A7I7JNC0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2492438:G6N19 RS08150
gene id: 2492438:G6N19_RS08150
uniprot id: A0A7I7JL08
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2492438:G6N19 RS07895
gene id: 2492438:G6N19_RS07895
uniprot id: A0A7I7JKV3
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

2492438:G6N19 RS08670
gene id: 2492438:G6N19_RS08670
uniprot id: A0A7I7JLK5
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

2492438:G6N19 RS16435
gene id: 2492438:G6N19_RS16435
uniprot id: A0A7I7JQX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS13515
gene id: 2492438:G6N19_RS13515
uniprot id: A0A7I7JP21
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

2492438:G6N19 RS08135
gene id: 2492438:G6N19_RS08135
uniprot id: A0A7I7JMT3
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

2492438:G6N19 RS13595
gene id: 2492438:G6N19_RS13595
uniprot id: A0A7I7JQY5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2492438:G6N19 RS11000
gene id: 2492438:G6N19_RS11000
uniprot id: A0A7I7JML7
names: Function
names: Similarity
messages: Belongs to the EgtB family.
messages: Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

2492438:G6N19 RS04515
gene id: 2492438:G6N19_RS04515
uniprot id: A0A7I7JKL1
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS02610
gene id: 2492438:G6N19_RS02610
uniprot id: A0A7I7JJL1
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS17610
gene id: 2492438:G6N19_RS17610
uniprot id: A0A7I7JTR2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

2492438:G6N19 RS00370
gene id: 2492438:G6N19_RS00370
uniprot id: A0A7I7JGI7
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

2492438:G6N19 RS00950
gene id: 2492438:G6N19_RS00950
uniprot id: A0A7I7JHA2
names: Similarity
messages: Belongs to the glutamine synthetase family.

2492438:G6N19 RS15920
gene id: 2492438:G6N19_RS15920
uniprot id: A0A7I7JQT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2492438:G6N19 RS18685
gene id: 2492438:G6N19_RS18685
uniprot id: A0A7I7JS39
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

2492438:G6N19 RS17050
gene id: 2492438:G6N19_RS17050
uniprot id: A0A7I7JSP1
names: Similarity
messages: Belongs to the DprA/Smf family.

2492438:G6N19 RS10430
gene id: 2492438:G6N19_RS10430
uniprot id: A0A7I7JP61
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

2492438:G6N19 RS00915
gene id: 2492438:G6N19_RS00915
uniprot id: A0A7I7JGP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

2492438:G6N19 RS16185
gene id: 2492438:G6N19_RS16185
uniprot id: A0A7I7JSD6
names: Similarity
messages: Belongs to the cytochrome P450 family.

2492438:G6N19 RS11475
gene id: 2492438:G6N19_RS11475
uniprot id: A0A7I7JP99
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS06310
gene id: 2492438:G6N19_RS06310
uniprot id: A0A7I7JLA6
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

2492438:G6N19 RS08825
gene id: 2492438:G6N19_RS08825
uniprot id: A0A7I7JLN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EspG family.
messages: Cytoplasm

2492438:G6N19 RS13860
gene id: 2492438:G6N19_RS13860
uniprot id: A0A7I7JR34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

2492438:G6N19 RS16570
gene id: 2492438:G6N19_RS16570
uniprot id: A0A7I7JR88
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family.

2492438:G6N19 RS00605
gene id: 2492438:G6N19_RS00605
uniprot id: A0A7I7JH30
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

2492438:G6N19 RS07695
gene id: 2492438:G6N19_RS07695
uniprot id: A0A7I7JM34
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

2492438:G6N19 RS20610
gene id: 2492438:G6N19_RS20610
uniprot id: A0A7I7JV00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

2492438:G6N19 RS00245
gene id: 2492438:G6N19_RS00245
uniprot id: A0A7I7JJ35
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

2492438:G6N19 RS03875
gene id: 2492438:G6N19_RS03875
uniprot id: A0A7I7JIE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2492438:G6N19 RS12430
gene id: 2492438:G6N19_RS12430
uniprot id: A0A7I7JNG0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

2492438:G6N19 RS10085
gene id: 2492438:G6N19_RS10085
uniprot id: A0A7I7JM00
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

2492438:G6N19 RS01750
gene id: 2492438:G6N19_RS01750
uniprot id: A0A7I7JH90
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

2492438:G6N19 RS17850
gene id: 2492438:G6N19_RS17850
uniprot id: A0A7I7JRP7
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.

2492438:G6N19 RS11545
gene id: 2492438:G6N19_RS11545
uniprot id: A0A7I7JNB6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS05920
gene id: 2492438:G6N19_RS05920
uniprot id: A0A7I7JLG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS00930
gene id: 2492438:G6N19_RS00930
uniprot id: A0A7I7JIF4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

2492438:G6N19 RS06510
gene id: 2492438:G6N19_RS06510
uniprot id: A0A7I7JLM6
names: Similarity
messages: Belongs to the mycobacterial A85 antigen family.

2492438:G6N19 RS18565
gene id: 2492438:G6N19_RS18565
uniprot id: A0A7I7JU88
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

2492438:G6N19 RS16590
gene id: 2492438:G6N19_RS16590
uniprot id: A0A7I7JQV7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2492438:G6N19 RS02420
gene id: 2492438:G6N19_RS02420
uniprot id: A0A7I7JHM4
names: Similarity
messages: Belongs to the MmpS family.

2492438:G6N19 RS04000
gene id: 2492438:G6N19_RS04000
uniprot id: A0A7I7JIZ7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS11375
gene id: 2492438:G6N19_RS11375
uniprot id: A0A7I7JP79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

2492438:G6N19 RS04525
gene id: 2492438:G6N19_RS04525
uniprot id: A0A7I7JIT3
names: Similarity
messages: Belongs to the peptidase S1C family.

2492438:G6N19 RS01165
gene id: 2492438:G6N19_RS01165
uniprot id: A0A7I7JH06
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

2492438:G6N19 RS02400
gene id: 2492438:G6N19_RS02400
uniprot id: A0A7I7JI43
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

2492438:G6N19 RS06215
gene id: 2492438:G6N19_RS06215
uniprot id: A0A7I7JL80
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

2492438:G6N19 RS16045
gene id: 2492438:G6N19_RS16045
uniprot id: A0A7I7JRW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

2492438:G6N19 RS18485
gene id: 2492438:G6N19_RS18485
uniprot id: A0A7I7JRX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

2492438:G6N19 RS13775
gene id: 2492438:G6N19_RS13775
uniprot id: A0A7I7JP77
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2492438:G6N19 RS02180
gene id: 2492438:G6N19_RS02180
uniprot id: A0A7I7JI03
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

2492438:G6N19 RS06910
gene id: 2492438:G6N19_RS06910
uniprot id: A0A7I7JLN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

2492438:G6N19 RS02635
gene id: 2492438:G6N19_RS02635
uniprot id: A0A7I7JIA5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2492438:G6N19 RS18460
gene id: 2492438:G6N19_RS18460
uniprot id: A0A7I7JS58
names: Similarity
messages: Belongs to the peptidase A24 family.

2492438:G6N19 RS20345
gene id: 2492438:G6N19_RS20345
uniprot id: A0A7I7JUA3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2492438:G6N19 RS03700
gene id: 2492438:G6N19_RS03700
uniprot id: A0A7I7JKY8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2492438:G6N19 RS17150
gene id: 2492438:G6N19_RS17150
uniprot id: A0A7I7JSR1
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

2492438:G6N19 RS05885
gene id: 2492438:G6N19_RS05885
uniprot id: A0A7I7JJM4
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

2492438:G6N19 RS10600
gene id: 2492438:G6N19_RS10600
uniprot id: A0A7I7JML8
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

2492438:G6N19 RS12645
gene id: 2492438:G6N19_RS12645
uniprot id: A0A7I7JNS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

2492438:G6N19 RS05140
gene id: 2492438:G6N19_RS05140
uniprot id: A0A7I7JKI5
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

2492438:G6N19 RS16900
gene id: 2492438:G6N19_RS16900
uniprot id: A0A7I7JSC3
names: Similarity
messages: Belongs to the acylphosphatase family.

2492438:G6N19 RS01180
gene id: 2492438:G6N19_RS01180
uniprot id: A0A7I7JHG7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2492438:G6N19 RS13530
gene id: 2492438:G6N19_RS13530
uniprot id: A0A7I7JQE6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

2492438:G6N19 RS02300
gene id: 2492438:G6N19_RS02300
uniprot id: A0A7I7JHI4
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

2492438:G6N19 RS00165
gene id: 2492438:G6N19_RS00165
uniprot id: A0A7I7JGD6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

2492438:G6N19 RS00255
gene id: 2492438:G6N19_RS00255
uniprot id: A0A7I7JIA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

2492438:G6N19 RS01170
gene id: 2492438:G6N19_RS01170
uniprot id: A0A7I7JI48
names: Similarity
messages: Belongs to the AccD/PCCB family.

2492438:G6N19 RS10915
gene id: 2492438:G6N19_RS10915
uniprot id: A0A7I7JP47
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

2492438:G6N19 RS09225
gene id: 2492438:G6N19_RS09225
uniprot id: A0A7I7JN38
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2492438:G6N19 RS07095
gene id: 2492438:G6N19_RS07095
uniprot id: A0A7I7JKC7
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

2492438:G6N19 RS02755
gene id: 2492438:G6N19_RS02755
uniprot id: A0A7I7JJW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

2492438:G6N19 RS06415
gene id: 2492438:G6N19_RS06415
uniprot id: A0A7I7JLK7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS17015
gene id: 2492438:G6N19_RS17015
uniprot id: A0A7I7JTF6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2492438:G6N19 RS14550
gene id: 2492438:G6N19_RS14550
uniprot id: A0A7I7JR85
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

2492438:G6N19 RS10950
gene id: 2492438:G6N19_RS10950
uniprot id: A0A7I7JML0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

2492438:G6N19 RS16160
gene id: 2492438:G6N19_RS16160
uniprot id: A0A7I7JS53
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2492438:G6N19 RS11210
gene id: 2492438:G6N19_RS11210
uniprot id: A0A7I7JMR0
names: Similarity
messages: Belongs to the GSP E family.

2492438:G6N19 RS18740
gene id: 2492438:G6N19_RS18740
uniprot id: A0A7I7JTC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

2492438:G6N19 RS12305
gene id: 2492438:G6N19_RS12305
uniprot id: A0A7I7JQA9
names: Similarity
messages: Belongs to the HIBADH-related family.

2492438:G6N19 RS02660
gene id: 2492438:G6N19_RS02660
uniprot id: A0A7I7JHP7
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

2492438:G6N19 RS07285
gene id: 2492438:G6N19_RS07285
uniprot id: A0A7I7JMA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

2492438:G6N19 RS02090
gene id: 2492438:G6N19_RS02090
uniprot id: A0A7I7JHE9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2492438:G6N19 RS01725
gene id: 2492438:G6N19_RS01725
uniprot id: A0A7I7JJ72
names: Similarity
messages: Belongs to the thioesterase family.

2492438:G6N19 RS00420
gene id: 2492438:G6N19_RS00420
uniprot id: A0A7I7JGJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

2492438:G6N19 RS17080
gene id: 2492438:G6N19_RS17080
uniprot id: A0A7I7JR37
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

2492438:G6N19 RS04550
gene id: 2492438:G6N19_RS04550
uniprot id: A0A7I7JKT8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2492438:G6N19 RS06360
gene id: 2492438:G6N19_RS06360
uniprot id: A0A7I7JLB6
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

2492438:G6N19 RS14245
gene id: 2492438:G6N19_RS14245
uniprot id: A0A7I7JQT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS04320
gene id: 2492438:G6N19_RS04320
uniprot id: A0A7I7JIP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EspG family.
messages: Cytoplasm

2492438:G6N19 RS12355
gene id: 2492438:G6N19_RS12355
uniprot id: A0A7I7JQB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

2492438:G6N19 RS18590
gene id: 2492438:G6N19_RS18590
uniprot id: A0A7I7JS24
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS10075
gene id: 2492438:G6N19_RS10075
uniprot id: A0A7I7JME0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

2492438:G6N19 RS07445
gene id: 2492438:G6N19_RS07445
uniprot id: A0A7I7JLY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

2492438:G6N19 RS12640
gene id: 2492438:G6N19_RS12640
uniprot id: A0A7I7JQ56
names: Similarity
messages: Belongs to the PstS family.

2492438:G6N19 RS16210
gene id: 2492438:G6N19_RS16210
uniprot id: A0A7I7JS63
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

2492438:G6N19 RS10610
gene id: 2492438:G6N19_RS10610
uniprot id: A0A7I7JPW0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2492438:G6N19 RS05825
gene id: 2492438:G6N19_RS05825
uniprot id: A0A7I7JKZ2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

2492438:G6N19 RS20840
gene id: 2492438:G6N19_RS20840
uniprot id: A0A7I7JUM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

2492438:G6N19 RS08120
gene id: 2492438:G6N19_RS08120
uniprot id: A0A7I7JMU7
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

2492438:G6N19 RS00960
gene id: 2492438:G6N19_RS00960
uniprot id: A0A7I7JGS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

2492438:G6N19 RS01645
gene id: 2492438:G6N19_RS01645
uniprot id: A0A7I7JJ52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

2492438:G6N19 RS03020
gene id: 2492438:G6N19_RS03020
uniprot id: A0A7I7JJS1
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

2492438:G6N19 RS17625
gene id: 2492438:G6N19_RS17625
uniprot id: A0A7I7JRD9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2492438:G6N19 RS02850
gene id: 2492438:G6N19_RS02850
uniprot id: A0A7I7JID9
names: Similarity
messages: Belongs to the mycobacterial PPE family.

2492438:G6N19 RS01980
gene id: 2492438:G6N19_RS01980
uniprot id: A0A7I7JHW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

2492438:G6N19 RS00905
gene id: 2492438:G6N19_RS00905
uniprot id: A0A7I7JIN6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

2492438:G6N19 RS13590
gene id: 2492438:G6N19_RS13590
uniprot id: A0A7I7JPA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2492438:G6N19 RS09290
gene id: 2492438:G6N19_RS09290
uniprot id: A0A7I7JP33
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

2492438:G6N19 RS05850
gene id: 2492438:G6N19_RS05850
uniprot id: A0A7I7JM74
names: Similarity
messages: Belongs to the UPF0336 family.

2492438:G6N19 RS18690
gene id: 2492438:G6N19_RS18690
uniprot id: A0A7I7JTB8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

2492438:G6N19 RS16660
gene id: 2492438:G6N19_RS16660
uniprot id: A0A7I7JSR3
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

2492438:G6N19 RS05505
gene id: 2492438:G6N19_RS05505
uniprot id: A0A7I7JJD7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2492438:G6N19 RS03825
gene id: 2492438:G6N19_RS03825
uniprot id: A0A7I7JID8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2492438:G6N19 RS07315
gene id: 2492438:G6N19_RS07315
uniprot id: A0A7I7JKU9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2492438:G6N19 RS03540
gene id: 2492438:G6N19_RS03540
uniprot id: A0A7I7JIQ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2492438:G6N19 RS01960
gene id: 2492438:G6N19_RS01960
uniprot id: A0A7I7JJ17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

2492438:G6N19 RS07035
gene id: 2492438:G6N19_RS07035
uniprot id: A0A7I7JM53
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. May play a role in favoring mycobacterial survival in phagocytes.

2492438:G6N19 RS17600
gene id: 2492438:G6N19_RS17600
uniprot id: A0A7I7JT01
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

2492438:G6N19 RS00265
gene id: 2492438:G6N19_RS00265
uniprot id: A0A7I7JGA4
names: Similarity
messages: Belongs to the universal stress protein A family.

2492438:G6N19 RS07990
gene id: 2492438:G6N19_RS07990
uniprot id: A0A7I7JKU3
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily.
messages: Homodimer.

2492438:G6N19 RS17310
gene id: 2492438:G6N19_RS17310
uniprot id: A0A7I7JT33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

2492438:G6N19 RS13770
gene id: 2492438:G6N19_RS13770
uniprot id: A0A7I7JQZ7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2492438:G6N19 RS04835
gene id: 2492438:G6N19_RS04835
uniprot id: A0A7I7JKC2
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

2492438:G6N19 RS00160
gene id: 2492438:G6N19_RS00160
uniprot id: A0A7I7JG80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

2492438:G6N19 RS14685
gene id: 2492438:G6N19_RS14685
uniprot id: A0A7I7JPW5
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

2492438:G6N19 RS11315
gene id: 2492438:G6N19_RS11315
uniprot id: A0A7I7JMT1
names: Similarity
messages: Belongs to the peptidase M1 family.

2492438:G6N19 RS01465
gene id: 2492438:G6N19_RS01465
uniprot id: A0A7I7JIC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2492438:G6N19 RS14380
gene id: 2492438:G6N19_RS14380
uniprot id: A0A7I7JPJ5
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

2492438:G6N19 RS11250
gene id: 2492438:G6N19_RS11250
uniprot id: A0A7I7JPM5
names: Subcellular Location Annotation
messages: Cytoplasm

2492438:G6N19 RS06575
gene id: 2492438:G6N19_RS06575
uniprot id: A0A7I7JMM0
names: Similarity
messages: Belongs to the UPF0336 family.

2492438:G6N19 RS09255
gene id: 2492438:G6N19_RS09255
uniprot id: A0A7I7JLI2
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

2492438:G6N19 RS12125
gene id: 2492438:G6N19_RS12125
uniprot id: A0A7I7JNA5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2492438:G6N19 RS18350
gene id: 2492438:G6N19_RS18350
uniprot id: A0A7I7JT46
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS20395
gene id: 2492438:G6N19_RS20395
uniprot id: A0A7I7JUB4
names: Similarity
messages: Belongs to the XFP family.

2492438:G6N19 RS07920
gene id: 2492438:G6N19_RS07920
uniprot id: A0A7I7JNB8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2492438:G6N19 RS20430
gene id: 2492438:G6N19_RS20430
uniprot id: A0A7I7JT58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

2492438:G6N19 RS16155
gene id: 2492438:G6N19_RS16155
uniprot id: A0A7I7JRY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

2492438:G6N19 RS17790
gene id: 2492438:G6N19_RS17790
uniprot id: A0A7I7JST1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS17040
gene id: 2492438:G6N19_RS17040
uniprot id: A0A7I7JR29
names: Similarity
messages: Belongs to the UPF0102 family.

2492438:G6N19 RS01930
gene id: 2492438:G6N19_RS01930
uniprot id: A0A7I7JHW0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2492438:G6N19 RS15940
gene id: 2492438:G6N19_RS15940
uniprot id: A0A7I7JQF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2492438:G6N19 RS13865
gene id: 2492438:G6N19_RS13865
uniprot id: A0A7I7JRP8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2492438:G6N19 RS02895
gene id: 2492438:G6N19_RS02895
uniprot id: A0A7I7JJH7
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

2492438:G6N19 RS01790
gene id: 2492438:G6N19_RS01790
uniprot id: A0A7I7JJ77
names: Similarity
messages: Belongs to the CsoR family.

2492438:G6N19 RS12595
gene id: 2492438:G6N19_RS12595
uniprot id: A0A7I7JQ46
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2492438:G6N19 RS12685
gene id: 2492438:G6N19_RS12685
uniprot id: A0A7I7JPX1
names: Similarity
messages: Belongs to the TfdA dioxygenase family.

2492438:G6N19 RS12270
gene id: 2492438:G6N19_RS12270
uniprot id: A0A7I7JQ71
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2492438:G6N19 RS02265
gene id: 2492438:G6N19_RS02265
uniprot id: A0A7I7JHK1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

2492438:G6N19 RS08200
gene id: 2492438:G6N19_RS08200
uniprot id: A0A7I7JL11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

2492438:G6N19 RS13765
gene id: 2492438:G6N19_RS13765
uniprot id: A0A7I7JPJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2492438:G6N19 RS01260
gene id: 2492438:G6N19_RS01260
uniprot id: A0A7I7JH25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cutinase family.
messages: Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle.
messages: Secreted

2492438:G6N19 RS19430
gene id: 2492438:G6N19_RS19430
uniprot id: A0A7I7JSI7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

2492438:G6N19 RS13650
gene id: 2492438:G6N19_RS13650
uniprot id: A0A7I7JRL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2492438:G6N19 RS04850
gene id: 2492438:G6N19_RS04850
uniprot id: A0A7I7JKZ7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2492438:G6N19 RS13290
gene id: 2492438:G6N19_RS13290
uniprot id: A0A7I7JP43
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

2492438:G6N19 RS20140
gene id: 2492438:G6N19_RS20140
uniprot id: A0A7I7JSX6
names: Similarity
messages: Belongs to the MmpS family.

2492438:G6N19 RS11610
gene id: 2492438:G6N19_RS11610
uniprot id: A0A7I7JN01
names: Similarity
messages: Belongs to the disproportionating enzyme family.

2492438:G6N19 RS12755
gene id: 2492438:G6N19_RS12755
uniprot id: A0A7I7JR41
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2492438:G6N19 RS01815
gene id: 2492438:G6N19_RS01815
uniprot id: A0A7I7JIZ4
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

2492438:G6N19 RS12385
gene id: 2492438:G6N19_RS12385
uniprot id: A0A7I7JNF4
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

2492438:G6N19 RS03755
gene id: 2492438:G6N19_RS03755
uniprot id: A0A7I7JIU7
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

2492438:G6N19 RS00715
gene id: 2492438:G6N19_RS00715
uniprot id: A0A7I7JGM6
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

2492438:G6N19 RS20225
gene id: 2492438:G6N19_RS20225
uniprot id: A0A7I7JUQ2
names: Similarity
messages: Belongs to the CinA family.

2492438:G6N19 RS07575
gene id: 2492438:G6N19_RS07575
uniprot id: A0A7I7JL15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EspG family.
messages: Cytoplasm

2492438:G6N19 RS02640
gene id: 2492438:G6N19_RS02640
uniprot id: A0A7I7JJP2
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

2492438:G6N19 RS20420
gene id: 2492438:G6N19_RS20420
uniprot id: A0A7I7JTC3
names: Similarity
messages: Belongs to the Apa family.

2492438:G6N19 RS05840
gene id: 2492438:G6N19_RS05840
uniprot id: A0A7I7JK01
names: Similarity
messages: Belongs to the UPF0336 family.

2492438:G6N19 RS10035
gene id: 2492438:G6N19_RS10035
uniprot id: A0A7I7JLZ2
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

2492438:G6N19 RS20325
gene id: 2492438:G6N19_RS20325
uniprot id: A0A7I7JUS5
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS02310
gene id: 2492438:G6N19_RS02310
uniprot id: A0A7I7JHJ0
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

2492438:G6N19 RS10230
gene id: 2492438:G6N19_RS10230
uniprot id: A0A7I7JP01
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

2492438:G6N19 RS13760
gene id: 2492438:G6N19_RS13760
uniprot id: A0A7I7JRN1
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

2492438:G6N19 RS12600
gene id: 2492438:G6N19_RS12600
uniprot id: A0A7I7JNR2
names: Similarity
messages: Belongs to the PstS family.

2492438:G6N19 RS01145
gene id: 2492438:G6N19_RS01145
uniprot id: A0A7I7JHE2
names: Similarity
messages: Belongs to the CdaR family.

2492438:G6N19 RS16205
gene id: 2492438:G6N19_RS16205
uniprot id: A0A7I7JRZ5
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

2492438:G6N19 RS04675
gene id: 2492438:G6N19_RS04675
uniprot id: A0A7I7JIW3
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS02855
gene id: 2492438:G6N19_RS02855
uniprot id: A0A7I7JJX9
names: Similarity
messages: Belongs to the mycobacterial PPE family.

2492438:G6N19 RS00925
gene id: 2492438:G6N19_RS00925
uniprot id: A0A7I7JHZ8
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS20120
gene id: 2492438:G6N19_RS20120
uniprot id: A0A7I7JT63
names: Similarity
messages: Belongs to the mycobacterial PPE family.

2492438:G6N19 RS19025
gene id: 2492438:G6N19_RS19025
uniprot id: A0A7I7JSC1
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS20445
gene id: 2492438:G6N19_RS20445
uniprot id: A0A7I7JUN1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

2492438:G6N19 RS12540
gene id: 2492438:G6N19_RS12540
uniprot id: A0A7I7JPU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

2492438:G6N19 RS10815
gene id: 2492438:G6N19_RS10815
uniprot id: A0A7I7JPF1
names: Similarity
messages: Belongs to the MmpS family.

2492438:G6N19 RS05290
gene id: 2492438:G6N19_RS05290
uniprot id: A0A7I7JKL5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2492438:G6N19 RS07345
gene id: 2492438:G6N19_RS07345
uniprot id: A0A7I7JKH3
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

2492438:G6N19 RS14880
gene id: 2492438:G6N19_RS14880
uniprot id: A0A7I7JPU4
names: Similarity
messages: Belongs to the TPP enzyme family.

2492438:G6N19 RS06330
gene id: 2492438:G6N19_RS06330
uniprot id: A0A7I7JMG4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

2492438:G6N19 RS15670
gene id: 2492438:G6N19_RS15670
uniprot id: A0A7I7JS31
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2492438:G6N19 RS20560
gene id: 2492438:G6N19_RS20560
uniprot id: A0A7I7JTF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

2492438:G6N19 RS18320
gene id: 2492438:G6N19_RS18320
uniprot id: A0A7I7JU43
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

2492438:G6N19 RS16735
gene id: 2492438:G6N19_RS16735
uniprot id: A0A7I7JQX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

2492438:G6N19 RS10985
gene id: 2492438:G6N19_RS10985
uniprot id: A0A7I7JQ44
names: Similarity
messages: Belongs to the OsmC/Ohr family.

2492438:G6N19 RS06290
gene id: 2492438:G6N19_RS06290
uniprot id: A0A7I7JLQ6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

2492438:G6N19 RS17835
gene id: 2492438:G6N19_RS17835
uniprot id: A0A7I7JRI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

2492438:G6N19 RS07280
gene id: 2492438:G6N19_RS07280
uniprot id: A0A7I7JKW1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

2492438:G6N19 RS07085
gene id: 2492438:G6N19_RS07085
uniprot id: A0A7I7JM63
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS18720
gene id: 2492438:G6N19_RS18720
uniprot id: A0A7I7JTR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Homopentamer.

2492438:G6N19 RS03220
gene id: 2492438:G6N19_RS03220
uniprot id: A0A7I7JJV1
names: Function
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Involved in the biosynthesis of ADP-glucose, a building block, required in the biosynthesis of maltose-1-phosphate (M1P) and in the elongation reactions to produce linear alpha-1,4-glucans. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

2492438:G6N19 RS07330
gene id: 2492438:G6N19_RS07330
uniprot id: A0A7I7JKX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

2492438:G6N19 RS19700
gene id: 2492438:G6N19_RS19700
uniprot id: A0A7I7JU75
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

2492438:G6N19 RS04555
gene id: 2492438:G6N19_RS04555
uniprot id: A0A7I7JLG8
names: Similarity
messages: Belongs to the AccD/PCCB family.

2492438:G6N19 RS16290
gene id: 2492438:G6N19_RS16290
uniprot id: A0A7I7JQU2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

2492438:G6N19 RS18650
gene id: 2492438:G6N19_RS18650
uniprot id: A0A7I7JS98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

2492438:G6N19 RS07380
gene id: 2492438:G6N19_RS07380
uniprot id: A0A7I7JKX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

2492438:G6N19 RS16555
gene id: 2492438:G6N19_RS16555
uniprot id: A0A7I7JR00
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

2492438:G6N19 RS01050
gene id: 2492438:G6N19_RS01050
uniprot id: A0A7I7JGU7
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

2492438:G6N19 RS12445
gene id: 2492438:G6N19_RS12445
uniprot id: A0A7I7JQ18
names: Similarity
messages: Belongs to the peptidase M18 family.

2492438:G6N19 RS16005
gene id: 2492438:G6N19_RS16005
uniprot id: A0A7I7JQM1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2492438:G6N19 RS13825
gene id: 2492438:G6N19_RS13825
uniprot id: A0A7I7JP93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

2492438:G6N19 RS00720
gene id: 2492438:G6N19_RS00720
uniprot id: A0A7I7JGJ6
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

2492438:G6N19 RS20460
gene id: 2492438:G6N19_RS20460
uniprot id: A0A7I7JVB1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

2492438:G6N19 RS13645
gene id: 2492438:G6N19_RS13645
uniprot id: A0A7I7JQZ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2492438:G6N19 RS15085
gene id: 2492438:G6N19_RS15085
uniprot id: A0A7I7JRC8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2492438:G6N19 RS07870
gene id: 2492438:G6N19_RS07870
uniprot id: A0A7I7JNA9
names: Function
names: Subunit
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.
messages: Monomer.

2492438:G6N19 RS13600
gene id: 2492438:G6N19_RS13600
uniprot id: A0A7I7JRK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2492438:G6N19 RS05385
gene id: 2492438:G6N19_RS05385
uniprot id: A0A7I7JLX4
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS00145
gene id: 2492438:G6N19_RS00145
uniprot id: A0A7I7JGS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

2492438:G6N19 RS03100
gene id: 2492438:G6N19_RS03100
uniprot id: A0A7I7JIH6
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

2492438:G6N19 RS01305
gene id: 2492438:G6N19_RS01305
uniprot id: A0A7I7JGY4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2492438:G6N19 RS08665
gene id: 2492438:G6N19_RS08665
uniprot id: A0A7I7JNR0
names: Similarity
messages: Belongs to the cytochrome P450 family.

2492438:G6N19 RS02765
gene id: 2492438:G6N19_RS02765
uniprot id: A0A7I7JIC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

2492438:G6N19 RS18890
gene id: 2492438:G6N19_RS18890
uniprot id: A0A7I7JTF2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

2492438:G6N19 RS15035
gene id: 2492438:G6N19_RS15035
uniprot id: A0A7I7JRB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

2492438:G6N19 RS19000
gene id: 2492438:G6N19_RS19000
uniprot id: A0A7I7JSF8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

2492438:G6N19 RS00610
gene id: 2492438:G6N19_RS00610
uniprot id: A0A7I7JIH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

2492438:G6N19 RS08540
gene id: 2492438:G6N19_RS08540
uniprot id: A0A7I7JL47
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

2492438:G6N19 RS02560
gene id: 2492438:G6N19_RS02560
uniprot id: A0A7I7JI71
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

2492438:G6N19 RS15595
gene id: 2492438:G6N19_RS15595
uniprot id: A0A7I7JRV4
names: Similarity
messages: Belongs to the DEAD box helicase family.

2492438:G6N19 RS02760
gene id: 2492438:G6N19_RS02760
uniprot id: A0A7I7JKF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2492438:G6N19 RS14870
gene id: 2492438:G6N19_RS14870
uniprot id: A0A7I7JQ63
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

2492438:G6N19 RS19330
gene id: 2492438:G6N19_RS19330
uniprot id: A0A7I7JSG8
names: Similarity
messages: Belongs to the peptidase C40 family.

2492438:G6N19 RS20650
gene id: 2492438:G6N19_RS20650
uniprot id: A0A7I7JVF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

2492438:G6N19 RS07985
gene id: 2492438:G6N19_RS07985
uniprot id: A0A7I7JMQ4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2492438:G6N19 RS17665
gene id: 2492438:G6N19_RS17665
uniprot id: A0A7I7JRV8
names: Similarity
messages: Belongs to the PspA/IM30 family.

2492438:G6N19 RS12885
gene id: 2492438:G6N19_RS12885
uniprot id: A0A7I7JQ08
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2492438:G6N19 RS01430
gene id: 2492438:G6N19_RS01430
uniprot id: A0A7I7JJ07
names: Similarity
messages: Belongs to the mycobacterial PPE family.

2492438:G6N19 RS07050
gene id: 2492438:G6N19_RS07050
uniprot id: A0A7I7JKE1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

2492438:G6N19 RS01635
gene id: 2492438:G6N19_RS01635
uniprot id: A0A7I7JJW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell envelope
messages: Exhibits GTPase activity. Binds RNA but is probably not involved in ribosome assembly in mycobacteria.
messages: Monomer.
messages: cell wall

2492438:G6N19 RS09685
gene id: 2492438:G6N19_RS09685
uniprot id: A0A7I7JNP3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2492438:G6N19 RS04085
gene id: 2492438:G6N19_RS04085
uniprot id: A0A7I7JJ02
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

2492438:G6N19 RS06555
gene id: 2492438:G6N19_RS06555
uniprot id: A0A7I7JLG0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

2492438:G6N19 RS13640
gene id: 2492438:G6N19_RS13640
uniprot id: A0A7I7JPB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

2492438:G6N19 RS00830
gene id: 2492438:G6N19_RS00830
uniprot id: A0A7I7JHX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

2492438:G6N19 RS21560
gene id: 2492438:G6N19_RS21560
uniprot id: A0A7I7JK08
names: Similarity
messages: Belongs to the mycobacterial PPE family.

2492438:G6N19 RS13085
gene id: 2492438:G6N19_RS13085
uniprot id: A0A7I7JQ53
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2492438:G6N19 RS14050
gene id: 2492438:G6N19_RS14050
uniprot id: A0A7I7JQX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

2492438:G6N19 RS17795
gene id: 2492438:G6N19_RS17795
uniprot id: A0A7I7JT40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

2492438:G6N19 RS17335
gene id: 2492438:G6N19_RS17335
uniprot id: A0A7I7JRF3
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS18280
gene id: 2492438:G6N19_RS18280
uniprot id: A0A7I7JTH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

2492438:G6N19 RS09145
gene id: 2492438:G6N19_RS09145
uniprot id: A0A7I7JP05
names: Similarity
messages: Belongs to the thioredoxin family.

2492438:G6N19 RS02620
gene id: 2492438:G6N19_RS02620
uniprot id: A0A7I7JHP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

2492438:G6N19 RS12525
gene id: 2492438:G6N19_RS12525
uniprot id: A0A7I7JNI2
names: Similarity
messages: Belongs to the TfdA dioxygenase family.

2492438:G6N19 RS02905
gene id: 2492438:G6N19_RS02905
uniprot id: A0A7I7JJY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2492438:G6N19 RS03285
gene id: 2492438:G6N19_RS03285
uniprot id: A0A7I7JI26
names: Similarity
messages: Belongs to the MmpS family.

2492438:G6N19 RS01670
gene id: 2492438:G6N19_RS01670
uniprot id: A0A7I7JHS5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

2492438:G6N19 RS03420
gene id: 2492438:G6N19_RS03420
uniprot id: A0A7I7JI51
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2492438:G6N19 RS04710
gene id: 2492438:G6N19_RS04710
uniprot id: A0A7I7JJC8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

2492438:G6N19 RS13920
gene id: 2492438:G6N19_RS13920
uniprot id: A0A7I7JPL8
names: Similarity
messages: Belongs to the WXG100 family.

2492438:G6N19 RS16535
gene id: 2492438:G6N19_RS16535
uniprot id: A0A7I7JR05
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

2492438:G6N19 RS03310
gene id: 2492438:G6N19_RS03310
uniprot id: A0A7I7JKR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

2492438:G6N19 RS02650
gene id: 2492438:G6N19_RS02650
uniprot id: A0A7I7JI83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

2492438:G6N19 RS15500
gene id: 2492438:G6N19_RS15500
uniprot id: A0A7I7JQC6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2492438:G6N19 RS19020
gene id: 2492438:G6N19_RS19020
uniprot id: A0A7I7JTX9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

2492438:G6N19 RS07935
gene id: 2492438:G6N19_RS07935
uniprot id: A0A7I7JKT0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2492438:G6N19 RS02175
gene id: 2492438:G6N19_RS02175
uniprot id: A0A7I7JK54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2492438:G6N19 RS07675
gene id: 2492438:G6N19_RS07675
uniprot id: A0A7I7JMK1
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

2492438:G6N19 RS17105
gene id: 2492438:G6N19_RS17105
uniprot id: A0A7I7JRA5
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS00495
gene id: 2492438:G6N19_RS00495
uniprot id: A0A7I7JJ82
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2492438:G6N19 RS05175
gene id: 2492438:G6N19_RS05175
uniprot id: A0A7I7JJ62
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

2492438:G6N19 RS00840
gene id: 2492438:G6N19_RS00840
uniprot id: A0A7I7JH84
names: Similarity
messages: Belongs to the asparagine synthetase family.

2492438:G6N19 RS17910
gene id: 2492438:G6N19_RS17910
uniprot id: A0A7I7JTW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

2492438:G6N19 RS07215
gene id: 2492438:G6N19_RS07215
uniprot id: A0A7I7JKT3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2492438:G6N19 RS11115
gene id: 2492438:G6N19_RS11115
uniprot id: A0A7I7JP28
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2492438:G6N19 RS02365
gene id: 2492438:G6N19_RS02365
uniprot id: A0A7I7JHL7
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

2492438:G6N19 RS20550
gene id: 2492438:G6N19_RS20550
uniprot id: A0A7I7JUY5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2492438:G6N19 RS06205
gene id: 2492438:G6N19_RS06205
uniprot id: A0A7I7JJU8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2492438:G6N19 RS17420
gene id: 2492438:G6N19_RS17420
uniprot id: A0A7I7JRQ1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2492438:G6N19 RS15310
gene id: 2492438:G6N19_RS15310
uniprot id: A0A7I7JQF8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2492438:G6N19 RS03965
gene id: 2492438:G6N19_RS03965
uniprot id: A0A7I7JIG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS19575
gene id: 2492438:G6N19_RS19575
uniprot id: A0A7I7JUA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2492438:G6N19 RS04110
gene id: 2492438:G6N19_RS04110
uniprot id: A0A7I7JIK2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS19160
gene id: 2492438:G6N19_RS19160
uniprot id: A0A7I7JUK5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2492438:G6N19 RS16580
gene id: 2492438:G6N19_RS16580
uniprot id: A0A7I7JQU9
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

2492438:G6N19 RS05725
gene id: 2492438:G6N19_RS05725
uniprot id: A0A7I7JKW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2492438:G6N19 RS18015
gene id: 2492438:G6N19_RS18015
uniprot id: A0A7I7JS11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS16180
gene id: 2492438:G6N19_RS16180
uniprot id: A0A7I7JQY8
names: Similarity
messages: Belongs to the cytochrome P450 family.

2492438:G6N19 RS06965
gene id: 2492438:G6N19_RS06965
uniprot id: A0A7I7JKN8
names: Function
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate.

2492438:G6N19 RS18570
gene id: 2492438:G6N19_RS18570
uniprot id: A0A7I7JSA5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

2492438:G6N19 RS15705
gene id: 2492438:G6N19_RS15705
uniprot id: A0A7I7JSN4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS17045
gene id: 2492438:G6N19_RS17045
uniprot id: A0A7I7JSE8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

2492438:G6N19 RS02795
gene id: 2492438:G6N19_RS02795
uniprot id: A0A7I7JJF7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2492438:G6N19 RS18695
gene id: 2492438:G6N19_RS18695
uniprot id: A0A7I7JTM0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

2492438:G6N19 RS04605
gene id: 2492438:G6N19_RS04605
uniprot id: A0A7I7JLH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

2492438:G6N19 RS02395
gene id: 2492438:G6N19_RS02395
uniprot id: A0A7I7JK90
names: Similarity
messages: Belongs to the AccD/PCCB family.

2492438:G6N19 RS13550
gene id: 2492438:G6N19_RS13550
uniprot id: A0A7I7JRJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2492438:G6N19 RS17215
gene id: 2492438:G6N19_RS17215
uniprot id: A0A7I7JTJ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2492438:G6N19 RS12610
gene id: 2492438:G6N19_RS12610
uniprot id: A0A7I7JNW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

2492438:G6N19 RS13955
gene id: 2492438:G6N19_RS13955
uniprot id: A0A7I7JPG4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

2492438:G6N19 RS20415
gene id: 2492438:G6N19_RS20415
uniprot id: A0A7I7JVA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2492438:G6N19 RS21660
gene id: 2492438:G6N19_RS21660
uniprot id: A0A7I7JT80
names: Similarity
messages: Belongs to the mycobacterial PPE family.

2492438:G6N19 RS13605
gene id: 2492438:G6N19_RS13605
uniprot id: A0A7I7JPF4
names: Similarity
messages: Belongs to the EccE family.

2492438:G6N19 RS09025
gene id: 2492438:G6N19_RS09025
uniprot id: A0A7I7JNY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

2492438:G6N19 RS07690
gene id: 2492438:G6N19_RS07690
uniprot id: A0A7I7JKR4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

2492438:G6N19 RS05125
gene id: 2492438:G6N19_RS05125
uniprot id: A0A7I7JJ48
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2492438:G6N19 RS02670
gene id: 2492438:G6N19_RS02670
uniprot id: A0A7I7JHR4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

2492438:G6N19 RS10730
gene id: 2492438:G6N19_RS10730
uniprot id: A0A7I7JMG3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

2492438:G6N19 RS05750
gene id: 2492438:G6N19_RS05750
uniprot id: A0A7I7JJX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2492438:G6N19 RS13555
gene id: 2492438:G6N19_RS13555
uniprot id: A0A7I7JPE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2492438:G6N19 RS00340
gene id: 2492438:G6N19_RS00340
uniprot id: A0A7I7JID4
names: Similarity
messages: Belongs to the UPF0235 family.

2492438:G6N19 RS10960
gene id: 2492438:G6N19_RS10960
uniprot id: A0A7I7JNZ5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS06270
gene id: 2492438:G6N19_RS06270
uniprot id: A0A7I7JK95
names: Similarity
messages: Belongs to the UPF0234 family.

2492438:G6N19 RS01155
gene id: 2492438:G6N19_RS01155
uniprot id: A0A7I7JGW8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Acyl carrier protein involved in meromycolate extension.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2492438:G6N19 RS10160
gene id: 2492438:G6N19_RS10160
uniprot id: A0A7I7JMD6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

2492438:G6N19 RS13400
gene id: 2492438:G6N19_RS13400
uniprot id: A0A7I7JPB8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2492438:G6N19 RS18345
gene id: 2492438:G6N19_RS18345
uniprot id: A0A7I7JRT2
names: Similarity
messages: Belongs to the DapA family.

2492438:G6N19 RS02500
gene id: 2492438:G6N19_RS02500
uniprot id: A0A7I7JJL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

2492438:G6N19 RS17645
gene id: 2492438:G6N19_RS17645
uniprot id: A0A7I7JT12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

2492438:G6N19 RS06700
gene id: 2492438:G6N19_RS06700
uniprot id: A0A7I7JK52
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2492438:G6N19 RS09150
gene id: 2492438:G6N19_RS09150
uniprot id: A0A7I7JLU6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

2492438:G6N19 RS08605
gene id: 2492438:G6N19_RS08605
uniprot id: A0A7I7JLI8
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

2492438:G6N19 RS18765
gene id: 2492438:G6N19_RS18765
uniprot id: A0A7I7JSE1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

2492438:G6N19 RS18715
gene id: 2492438:G6N19_RS18715
uniprot id: A0A7I7JSD5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

2492438:G6N19 RS07365
gene id: 2492438:G6N19_RS07365
uniprot id: A0A7I7JKV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

2492438:G6N19 RS15220
gene id: 2492438:G6N19_RS15220
uniprot id: A0A7I7JQ11
names: Subcellular Location Annotation
messages: Membrane

2492438:G6N19 RS14025
gene id: 2492438:G6N19_RS14025
uniprot id: A0A7I7JR47
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2492438:G6N19 RS19425
gene id: 2492438:G6N19_RS19425
uniprot id: A0A7I7JSK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

2492438:G6N19 RS01470
gene id: 2492438:G6N19_RS01470
uniprot id: A0A7I7JIR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2492438:G6N19 RS00805
gene id: 2492438:G6N19_RS00805
uniprot id: A0A7I7JH75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

2492438:G6N19 RS01825
gene id: 2492438:G6N19_RS01825
uniprot id: A0A7I7JJ90
names: Function
names: Subunit
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.
messages: Monomer.

2492438:G6N19 RS19625
gene id: 2492438:G6N19_RS19625
uniprot id: A0A7I7JUB5
names: Subcellular Location Annotation
messages: Cytoplasm

2492438:G6N19 RS18300
gene id: 2492438:G6N19_RS18300
uniprot id: A0A7I7JT35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

2492438:G6N19 RS15930
gene id: 2492438:G6N19_RS15930
uniprot id: A0A7I7JQF3
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

2492438:G6N19 RS17870
gene id: 2492438:G6N19_RS17870
uniprot id: A0A7I7JTB1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

2492438:G6N19 RS02535
gene id: 2492438:G6N19_RS02535
uniprot id: A0A7I7JIY3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2492438:G6N19 RS15080
gene id: 2492438:G6N19_RS15080
uniprot id: A0A7I7JPY4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

2492438:G6N19 RS15345
gene id: 2492438:G6N19_RS15345
uniprot id: A0A7I7JQ95
names: Similarity
messages: Belongs to the band 7/mec-2 family.

2492438:G6N19 RS18475
gene id: 2492438:G6N19_RS18475
uniprot id: A0A7I7JS88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

2492438:G6N19 RS18380
gene id: 2492438:G6N19_RS18380
uniprot id: A0A7I7JTJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

2492438:G6N19 RS17845
gene id: 2492438:G6N19_RS17845
uniprot id: A0A7I7JT50
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

2492438:G6N19 RS00365
gene id: 2492438:G6N19_RS00365
uniprot id: A0A7I7JGC6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

2492438:G6N19 RS11695
gene id: 2492438:G6N19_RS11695
uniprot id: A0A7I7JNF3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2492438:G6N19 RS01830
gene id: 2492438:G6N19_RS01830
uniprot id: A0A7I7JJZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm