246200:SPO RS21245
gene id: 246200:SPO_RS21245
uniprot id: Q5LKU8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS10385
gene id: 246200:SPO_RS10385
uniprot id: Q5LRS8
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

246200:SPO RS09445
gene id: 246200:SPO_RS09445
uniprot id: Q5LSB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

246200:SPO RS18700
gene id: 246200:SPO_RS18700
uniprot id: Q5LM78
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

246200:SPO RS18260
gene id: 246200:SPO_RS18260
uniprot id: Q5LMF9
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS14140
gene id: 246200:SPO_RS14140
uniprot id: Q5LPR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

246200:SPO RS08530
gene id: 246200:SPO_RS08530
uniprot id: Q5LST6
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

246200:SPO RS06930
gene id: 246200:SPO_RS06930
uniprot id: Q5LTQ4
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

246200:SPO RS01435
gene id: 246200:SPO_RS01435
uniprot id: Q5LX62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

246200:SPO RS06140
gene id: 246200:SPO_RS06140
uniprot id: Q5LU48
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

246200:SPO RS14800
gene id: 246200:SPO_RS14800
uniprot id: Q5LPD0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

246200:SPO RS00760
gene id: 246200:SPO_RS00760
uniprot id: Q5LWV5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

246200:SPO RS11520
gene id: 246200:SPO_RS11520
uniprot id: Q5LR59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

246200:SPO RS04750
gene id: 246200:SPO_RS04750
uniprot id: Q5LUV6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

246200:SPO RS14430
gene id: 246200:SPO_RS14430
uniprot id: Q5LPK7
names: Similarity
messages: Belongs to the peptidase M1 family.

246200:SPO RS14090
gene id: 246200:SPO_RS14090
uniprot id: Q5LPS5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

246200:SPO RS11290
gene id: 246200:SPO_RS11290
uniprot id: Q5LRA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

246200:SPO RS01615
gene id: 246200:SPO_RS01615
uniprot id: Q5LXA0
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

246200:SPO RS22080
gene id: 246200:SPO_RS22080
uniprot id: Q5LKD5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS15890
gene id: 246200:SPO_RS15890
uniprot id: Q5LNR7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

246200:SPO RS13145
gene id: 246200:SPO_RS13145
uniprot id: Q5LQA2
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

246200:SPO RS00165
gene id: 246200:SPO_RS00165
uniprot id: Q5LWI7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS07895
gene id: 246200:SPO_RS07895
uniprot id: Q5LT63
names: Function
names: Similarity
messages: Belongs to the FMO family.
messages: Catalyzes the oxidation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) (PubMed:22006322). In vitro, has a broad substrate specificity, oxidizing many nitrogen- and sulfur-containing compounds, including dimethylamine (DMA), dimethylsulfide (DMS) and dimethylsulfoxide (DMSO) (PubMed:22006322).

246200:SPO RS06955
gene id: 246200:SPO_RS06955
uniprot id: Q5LTP9
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

246200:SPO RS17280
gene id: 246200:SPO_RS17280
uniprot id: Q5LMZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

246200:SPO RS20025
gene id: 246200:SPO_RS20025
uniprot id: Q5LLH7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NosZ family.
messages: Binds 2 calcium ions per subunit.
messages: Binds 6 Cu cations per subunit. Each subunit contains 2 copper centers; Cu(A) (binuclear) and Cu(Z) (tetranuclear). Cu(Z) is thought to be the site of nitrous oxide reduction.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

246200:SPO RS12300
gene id: 246200:SPO_RS12300
uniprot id: Q5LQR7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

246200:SPO RS12435
gene id: 246200:SPO_RS12435
uniprot id: Q5LQP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

246200:SPO RS18195
gene id: 246200:SPO_RS18195
uniprot id: Q5LMH1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS07985
gene id: 246200:SPO_RS07985
uniprot id: Q5LT45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

246200:SPO RS00030
gene id: 246200:SPO_RS00030
uniprot id: Q5LWF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

246200:SPO RS07210
gene id: 246200:SPO_RS07210
uniprot id: Q5LTK1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

246200:SPO RS19305
gene id: 246200:SPO_RS19305
uniprot id: Q5LLW6
names: Disruption Phenotype
names: Function
names: Similarity
names: Subunit
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Cells lacking this gene do not grow on methylmercaptopropionate (MMPA) as the sole source of carbon. Growth is severely inhibited on dimethylsulphoniopropionate (DMSP).
messages: Homohexamer; dimer of trimers.
messages: Involved in the assimilation of dimethylsulphoniopropionate (DMSP), an important compound in the fixation of carbon in marine phytoplankton, by catalyzing both the hydration and the hydrolysis of 3-(methylthio)acryloyl-CoA (MTA-CoA) to acetaldehyde, CO2, MeSH, and CoA (PubMed:21562561, PubMed:23704947).

246200:SPO RS06145
gene id: 246200:SPO_RS06145
uniprot id: Q5LU47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

246200:SPO RS05870
gene id: 246200:SPO_RS05870
uniprot id: Q5LU97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

246200:SPO RS11535
gene id: 246200:SPO_RS11535
uniprot id: Q5LR56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

246200:SPO RS03865
gene id: 246200:SPO_RS03865
uniprot id: Q5LVD6
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

246200:SPO RS19830
gene id: 246200:SPO_RS19830
uniprot id: Q5LLL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

246200:SPO RS06485
gene id: 246200:SPO_RS06485
uniprot id: Q5LTY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

246200:SPO RS15865
gene id: 246200:SPO_RS15865
uniprot id: Q5LNS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP.
messages: Membrane

246200:SPO RS03935
gene id: 246200:SPO_RS03935
uniprot id: Q5LVC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PhnC), two transmembrane proteins (PhnE) and a solute-binding protein (PhnD).

246200:SPO RS05855
gene id: 246200:SPO_RS05855
uniprot id: Q5LUA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

246200:SPO RS07165
gene id: 246200:SPO_RS07165
uniprot id: Q5LTL0
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS15495
gene id: 246200:SPO_RS15495
uniprot id: Q5LNZ4
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS17195
gene id: 246200:SPO_RS17195
uniprot id: Q5LN16
names: Similarity
messages: Belongs to the GcvT family.

246200:SPO RS21725
gene id: 246200:SPO_RS21725
uniprot id: Q5LKK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS10265
gene id: 246200:SPO_RS10265
uniprot id: Q5LRV0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

246200:SPO RS06625
gene id: 246200:SPO_RS06625
uniprot id: Q5LTW2
names: Similarity
messages: Belongs to the glutamine synthetase family.

246200:SPO RS01720
gene id: 246200:SPO_RS01720
uniprot id: Q5LXD3
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS16015
gene id: 246200:SPO_RS16015
uniprot id: Q5LNP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

246200:SPO RS10230
gene id: 246200:SPO_RS10230
uniprot id: Q5LRV7
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS05680
gene id: 246200:SPO_RS05680
uniprot id: Q5LUD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

246200:SPO RS21765
gene id: 246200:SPO_RS21765
uniprot id: Q5LKK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

246200:SPO RS01885
gene id: 246200:SPO_RS01885
uniprot id: Q5LXF4
names: Similarity
messages: Belongs to the autoinducer synthase family.

246200:SPO RS00130
gene id: 246200:SPO_RS00130
uniprot id: Q5LWH5
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

246200:SPO RS07630
gene id: 246200:SPO_RS07630
uniprot id: Q5LTB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

246200:SPO RS10220
gene id: 246200:SPO_RS10220
uniprot id: Q5LRV9
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

246200:SPO RS20165
gene id: 246200:SPO_RS20165
uniprot id: Q5LLE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

246200:SPO RS21170
gene id: 246200:SPO_RS21170
uniprot id: Q5LKW2
names: Similarity
messages: Belongs to the DapA family.

246200:SPO RS04880
gene id: 246200:SPO_RS04880
uniprot id: Q5LUT2
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

246200:SPO RS13330
gene id: 246200:SPO_RS13330
uniprot id: Q5LQ68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

246200:SPO RS02450
gene id: 246200:SPO_RS02450
uniprot id: Q5LW57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

246200:SPO RS17260
gene id: 246200:SPO_RS17260
uniprot id: Q5LN03
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

246200:SPO RS16915
gene id: 246200:SPO_RS16915
uniprot id: Q5LN73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

246200:SPO RS11345
gene id: 246200:SPO_RS11345
uniprot id: Q5LR91
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS17725
gene id: 246200:SPO_RS17725
uniprot id: Q5LMR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

246200:SPO RS01455
gene id: 246200:SPO_RS01455
uniprot id: Q5LX75
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

246200:SPO RS13460
gene id: 246200:SPO_RS13460
uniprot id: Q5LQ43
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

246200:SPO RS16590
gene id: 246200:SPO_RS16590
uniprot id: Q5LND5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

246200:SPO RS11775
gene id: 246200:SPO_RS11775
uniprot id: Q5LR09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

246200:SPO RS03340
gene id: 246200:SPO_RS03340
uniprot id: Q5LVN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

246200:SPO RS00330
gene id: 246200:SPO_RS00330
uniprot id: Q5LWL0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

246200:SPO RS00415
gene id: 246200:SPO_RS00415
uniprot id: Q5LWM9
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

246200:SPO RS01760
gene id: 246200:SPO_RS01760
uniprot id: Q5LXC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

246200:SPO RS02630
gene id: 246200:SPO_RS02630
uniprot id: Q5LW22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

246200:SPO RS09760
gene id: 246200:SPO_RS09760
uniprot id: Q5LS47
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

246200:SPO RS01480
gene id: 246200:SPO_RS01480
uniprot id: Q5LX71
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

246200:SPO RS19825
gene id: 246200:SPO_RS19825
uniprot id: Q5LLL1
names: Similarity
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.

246200:SPO RS09810
gene id: 246200:SPO_RS09810
uniprot id: Q5LS38
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

246200:SPO RS03555
gene id: 246200:SPO_RS03555
uniprot id: Q5LVJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

246200:SPO RS09560
gene id: 246200:SPO_RS09560
uniprot id: Q5LS87
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

246200:SPO RS15150
gene id: 246200:SPO_RS15150
uniprot id: Q5LP61
names: Subcellular Location Annotation
messages: Cell membrane

246200:SPO RS04575
gene id: 246200:SPO_RS04575
uniprot id: Q5LUZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

246200:SPO RS06690
gene id: 246200:SPO_RS06690
uniprot id: Q5LTV0
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

246200:SPO RS07025
gene id: 246200:SPO_RS07025
uniprot id: Q5LTN6
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

246200:SPO RS08560
gene id: 246200:SPO_RS08560
uniprot id: Q5LSS9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

246200:SPO RS11365
gene id: 246200:SPO_RS11365
uniprot id: Q5LR87
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

246200:SPO RS06635
gene id: 246200:SPO_RS06635
uniprot id: Q5LTW0
names: Similarity
messages: Belongs to the glutamine synthetase family.

246200:SPO RS08695
gene id: 246200:SPO_RS08695
uniprot id: Q5LSQ7
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS01825
gene id: 246200:SPO_RS01825
uniprot id: Q5LXE9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

246200:SPO RS09010
gene id: 246200:SPO_RS09010
uniprot id: Q5LSJ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS13850
gene id: 246200:SPO_RS13850
uniprot id: Q5LPW9
names: Similarity
messages: Belongs to the peptidase C40 family.

246200:SPO RS09920
gene id: 246200:SPO_RS09920
uniprot id: Q5LS16
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS17015
gene id: 246200:SPO_RS17015
uniprot id: Q5LN53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 1 Zn(2+) ion per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

246200:SPO RS10345
gene id: 246200:SPO_RS10345
uniprot id: Q5LRT5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

246200:SPO RS14795
gene id: 246200:SPO_RS14795
uniprot id: Q5LPD1
names: Similarity
messages: Belongs to the GST superfamily.

246200:SPO RS16375
gene id: 246200:SPO_RS16375
uniprot id: Q5LNH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

246200:SPO RS06405
gene id: 246200:SPO_RS06405
uniprot id: Q5LU03
names: Similarity
messages: Belongs to the GST superfamily.

246200:SPO RS11330
gene id: 246200:SPO_RS11330
uniprot id: Q5LR95
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

246200:SPO RS15575
gene id: 246200:SPO_RS15575
uniprot id: Q5LNX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

246200:SPO RS10305
gene id: 246200:SPO_RS10305
uniprot id: Q5LRU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

246200:SPO RS10505
gene id: 246200:SPO_RS10505
uniprot id: Q5LRQ4
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS19595
gene id: 246200:SPO_RS19595
uniprot id: Q5LLR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

246200:SPO RS03910
gene id: 246200:SPO_RS03910
uniprot id: Q5LVC7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

246200:SPO RS10905
gene id: 246200:SPO_RS10905
uniprot id: Q5LRH7
names: Similarity
messages: Belongs to the TrpC family.

246200:SPO RS15775
gene id: 246200:SPO_RS15775
uniprot id: Q5LNU0
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

246200:SPO RS12965
gene id: 246200:SPO_RS12965
uniprot id: Q5LQD4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

246200:SPO RS05460
gene id: 246200:SPO_RS05460
uniprot id: Q5LUH8
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS02710
gene id: 246200:SPO_RS02710
uniprot id: Q5LW06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

246200:SPO RS13760
gene id: 246200:SPO_RS13760
uniprot id: Q5LPY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

246200:SPO RS02570
gene id: 246200:SPO_RS02570
uniprot id: Q5LW34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

246200:SPO RS14480
gene id: 246200:SPO_RS14480
uniprot id: Q5LPJ6
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS00995
gene id: 246200:SPO_RS00995
uniprot id: Q5LWZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

246200:SPO RS02535
gene id: 246200:SPO_RS02535
uniprot id: Q5LW41
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

246200:SPO RS13170
gene id: 246200:SPO_RS13170
uniprot id: Q5LQ97
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

246200:SPO RS00870
gene id: 246200:SPO_RS00870
uniprot id: Q5LWW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

246200:SPO RS07525
gene id: 246200:SPO_RS07525
uniprot id: Q5LTD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

246200:SPO RS15900
gene id: 246200:SPO_RS15900
uniprot id: Q5LNR5
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS12865
gene id: 246200:SPO_RS12865
uniprot id: Q5LQF5
names: Similarity
messages: Belongs to the histone deacetylase family.

246200:SPO RS10015
gene id: 246200:SPO_RS10015
uniprot id: Q5LRZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

246200:SPO RS16225
gene id: 246200:SPO_RS16225
uniprot id: Q5LNK1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

246200:SPO RS00240
gene id: 246200:SPO_RS00240
uniprot id: Q5LWJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

246200:SPO RS17295
gene id: 246200:SPO_RS17295
uniprot id: Q5LMZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

246200:SPO RS20940
gene id: 246200:SPO_RS20940
uniprot id: Q5LL08
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

246200:SPO RS21385
gene id: 246200:SPO_RS21385
uniprot id: Q5LKS1
names: Similarity
messages: Belongs to the GcvT family.

246200:SPO RS05530
gene id: 246200:SPO_RS05530
uniprot id: Q5LUG4
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

246200:SPO RS15190
gene id: 246200:SPO_RS15190
uniprot id: Q5LP54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

246200:SPO RS05640
gene id: 246200:SPO_RS05640
uniprot id: Q5LUE3
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

246200:SPO RS13610
gene id: 246200:SPO_RS13610
uniprot id: Q5LQ13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

246200:SPO RS09415
gene id: 246200:SPO_RS09415
uniprot id: Q5LSB7
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS00495
gene id: 246200:SPO_RS00495
uniprot id: Q5LWP9
names: Subcellular Location Annotation
messages: Cell inner membrane

246200:SPO RS21730
gene id: 246200:SPO_RS21730
uniprot id: Q5LKK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

246200:SPO RS12650
gene id: 246200:SPO_RS12650
uniprot id: Q5LQJ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

246200:SPO RS06530
gene id: 246200:SPO_RS06530
uniprot id: Q5LTX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

246200:SPO RS12775
gene id: 246200:SPO_RS12775
uniprot id: Q5LQH3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

246200:SPO RS04565
gene id: 246200:SPO_RS04565
uniprot id: Q5LUZ6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

246200:SPO RS02460
gene id: 246200:SPO_RS02460
uniprot id: Q5LW55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

246200:SPO RS09870
gene id: 246200:SPO_RS09870
uniprot id: Q5LS26
names: Similarity
messages: Belongs to the YicC/YloC family.

246200:SPO RS13000
gene id: 246200:SPO_RS13000
uniprot id: Q5LQC9
names: Similarity
messages: Belongs to the hyi family.

246200:SPO RS17780
gene id: 246200:SPO_RS17780
uniprot id: Q5LMQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

246200:SPO RS17570
gene id: 246200:SPO_RS17570
uniprot id: Q5LMU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

246200:SPO RS03500
gene id: 246200:SPO_RS03500
uniprot id: Q5LVK7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

246200:SPO RS02215
gene id: 246200:SPO_RS02215
uniprot id: Q5LWA4
names: Similarity
messages: Belongs to the YkuD family.

246200:SPO RS17440
gene id: 246200:SPO_RS17440
uniprot id: Q5LMW7
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

246200:SPO RS14400
gene id: 246200:SPO_RS14400
uniprot id: Q5LPL3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

246200:SPO RS00510
gene id: 246200:SPO_RS00510
uniprot id: Q5LWP6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

246200:SPO RS08725
gene id: 246200:SPO_RS08725
uniprot id: Q5LSQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

246200:SPO RS14940
gene id: 246200:SPO_RS14940
uniprot id: Q5LPA2
names: Similarity
messages: Belongs to the FMO family.

246200:SPO RS08800
gene id: 246200:SPO_RS08800
uniprot id: Q5LSN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

246200:SPO RS18710
gene id: 246200:SPO_RS18710
uniprot id: Q5LM76
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

246200:SPO RS15365
gene id: 246200:SPO_RS15365
uniprot id: Q5LP21
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

246200:SPO RS19090
gene id: 246200:SPO_RS19090
uniprot id: Q5LM02
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

246200:SPO RS15260
gene id: 246200:SPO_RS15260
uniprot id: Q5LP42
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

246200:SPO RS10605
gene id: 246200:SPO_RS10605
uniprot id: Q5LRN4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

246200:SPO RS04720
gene id: 246200:SPO_RS04720
uniprot id: Q5LUW2
names: Similarity
messages: Belongs to the IMPACT family.

246200:SPO RS21435
gene id: 246200:SPO_RS21435
uniprot id: Q5LKR2
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

246200:SPO RS14025
gene id: 246200:SPO_RS14025
uniprot id: Q5LPT8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

246200:SPO RS18960
gene id: 246200:SPO_RS18960
uniprot id: Q5LM28
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

246200:SPO RS14845
gene id: 246200:SPO_RS14845
uniprot id: Q5LPC1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

246200:SPO RS17220
gene id: 246200:SPO_RS17220
uniprot id: Q5LN11
names: Similarity
messages: Belongs to the Gfa family.

246200:SPO RS18895
gene id: 246200:SPO_RS18895
uniprot id: Q5LM41
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

246200:SPO RS17330
gene id: 246200:SPO_RS17330
uniprot id: Q5LMY9
names: Similarity
messages: Belongs to the thioredoxin family.

246200:SPO RS12475
gene id: 246200:SPO_RS12475
uniprot id: Q5LQN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

246200:SPO RS00395
gene id: 246200:SPO_RS00395
uniprot id: Q5LWN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

246200:SPO RS21305
gene id: 246200:SPO_RS21305
uniprot id: Q5LKT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

246200:SPO RS02095
gene id: 246200:SPO_RS02095
uniprot id: Q5LWC8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

246200:SPO RS04890
gene id: 246200:SPO_RS04890
uniprot id: Q5LUT0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

246200:SPO RS08420
gene id: 246200:SPO_RS08420
uniprot id: Q5LSV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS08030
gene id: 246200:SPO_RS08030
uniprot id: Q5LT36
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS07420
gene id: 246200:SPO_RS07420
uniprot id: Q5LTF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS08455
gene id: 246200:SPO_RS08455
uniprot id: Q5LSV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

246200:SPO RS07845
gene id: 246200:SPO_RS07845
uniprot id: Q5LT73
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS02685
gene id: 246200:SPO_RS02685
uniprot id: Q5LW11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

246200:SPO RS13375
gene id: 246200:SPO_RS13375
uniprot id: Q5LQ59
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

246200:SPO RS16440
gene id: 246200:SPO_RS16440
uniprot id: Q5LNF9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

246200:SPO RS08715
gene id: 246200:SPO_RS08715
uniprot id: Q5LSQ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

246200:SPO RS15745
gene id: 246200:SPO_RS15745
uniprot id: Q5LNU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

246200:SPO RS08300
gene id: 246200:SPO_RS08300
uniprot id: Q5LSY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

246200:SPO RS10935
gene id: 246200:SPO_RS10935
uniprot id: Q5LRH1
names: Similarity
messages: Belongs to the citrate synthase family.

246200:SPO RS04520
gene id: 246200:SPO_RS04520
uniprot id: Q5LV05
names: Similarity
messages: Belongs to the PhzF family.

246200:SPO RS18870
gene id: 246200:SPO_RS18870
uniprot id: Q5LM46
names: Similarity
messages: Belongs to the peptidase C40 family.

246200:SPO RS05015
gene id: 246200:SPO_RS05015
uniprot id: Q5LUQ7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Binds 2 heme groups per subunit.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

246200:SPO RS15785
gene id: 246200:SPO_RS15785
uniprot id: Q5LNT8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

246200:SPO RS03000
gene id: 246200:SPO_RS03000
uniprot id: Q5LVV1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family. HpsN subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD-dependent oxidation of (R)-2,3-dihydroxypropane-1-sulfonate to (R)-3-sulfolactate.

246200:SPO RS12375
gene id: 246200:SPO_RS12375
uniprot id: Q5LQQ2
names: Similarity
messages: Belongs to the GcvT family.

246200:SPO RS09625
gene id: 246200:SPO_RS09625
uniprot id: Q5LS74
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

246200:SPO RS01360
gene id: 246200:SPO_RS01360
uniprot id: Q5LX60
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

246200:SPO RS16030
gene id: 246200:SPO_RS16030
uniprot id: Q5LNN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

246200:SPO RS00300
gene id: 246200:SPO_RS00300
uniprot id: Q5LWL6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e. capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

246200:SPO RS03720
gene id: 246200:SPO_RS03720
uniprot id: Q5LVG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS00850
gene id: 246200:SPO_RS00850
uniprot id: Q5LWW9
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

246200:SPO RS08000
gene id: 246200:SPO_RS08000
uniprot id: Q5LPA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

246200:SPO RS14105
gene id: 246200:SPO_RS14105
uniprot id: Q5LPS2
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

246200:SPO RS18205
gene id: 246200:SPO_RS18205
uniprot id: Q5LMG9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

246200:SPO RS09595
gene id: 246200:SPO_RS09595
uniprot id: Q5LS80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

246200:SPO RS19345
gene id: 246200:SPO_RS19345
uniprot id: Q5LLV9
names: Similarity
messages: Belongs to the peptidase S41A family.

246200:SPO RS14155
gene id: 246200:SPO_RS14155
uniprot id: Q5LPR2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

246200:SPO RS14755
gene id: 246200:SPO_RS14755
uniprot id: Q5LPE0
names: Similarity
messages: Belongs to the ArsC family.

246200:SPO RS20770
gene id: 246200:SPO_RS20770
uniprot id: Q5LL42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.
messages: Membrane

246200:SPO RS02005
gene id: 246200:SPO_RS02005
uniprot id: Q5LWE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

246200:SPO RS13495
gene id: 246200:SPO_RS13495
uniprot id: Q5LQ36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

246200:SPO RS18955
gene id: 246200:SPO_RS18955
uniprot id: Q5LM29
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS21685
gene id: 246200:SPO_RS21685
uniprot id: Q5LKL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

246200:SPO RS21105
gene id: 246200:SPO_RS21105
uniprot id: Q5LKX5
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS05990
gene id: 246200:SPO_RS05990
uniprot id: Q5LU76
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

246200:SPO RS05975
gene id: 246200:SPO_RS05975
uniprot id: Q5LU79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

246200:SPO RS13940
gene id: 246200:SPO_RS13940
uniprot id: Q5LPV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

246200:SPO RS14285
gene id: 246200:SPO_RS14285
uniprot id: Q5LPN6
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

246200:SPO RS02090
gene id: 246200:SPO_RS02090
uniprot id: Q5LWC9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

246200:SPO RS03525
gene id: 246200:SPO_RS03525
uniprot id: Q5LVK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

246200:SPO RS10790
gene id: 246200:SPO_RS10790
uniprot id: Q5LRJ9
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS02375
gene id: 246200:SPO_RS02375
uniprot id: Q5LW71
names: Function
names: Similarity
messages: Belongs to the PhnJ family.
messages: Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose.

246200:SPO RS16435
gene id: 246200:SPO_RS16435
uniprot id: Q5LNG0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

246200:SPO RS01275
gene id: 246200:SPO_RS01275
uniprot id: Q5LX39
names: Similarity
messages: Belongs to the histone deacetylase family.

246200:SPO RS15285
gene id: 246200:SPO_RS15285
uniprot id: Q5LP37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

246200:SPO RS17085
gene id: 246200:SPO_RS17085
uniprot id: Q5LN39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

246200:SPO RS10455
gene id: 246200:SPO_RS10455
uniprot id: Q5LRR4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

246200:SPO RS02725
gene id: 246200:SPO_RS02725
uniprot id: Q5LW03
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

246200:SPO RS11760
gene id: 246200:SPO_RS11760
uniprot id: Q5LR12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

246200:SPO RS06855
gene id: 246200:SPO_RS06855
uniprot id: Q5LTR8
names: Similarity
messages: Belongs to the GARS family.

246200:SPO RS16615
gene id: 246200:SPO_RS16615
uniprot id: Q5LND0
names: Similarity
messages: Belongs to the DinB family.

246200:SPO RS09565
gene id: 246200:SPO_RS09565
uniprot id: Q5LS86
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

246200:SPO RS10240
gene id: 246200:SPO_RS10240
uniprot id: Q5LRV5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

246200:SPO RS11510
gene id: 246200:SPO_RS11510
uniprot id: Q5LR61
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

246200:SPO RS16995
gene id: 246200:SPO_RS16995
uniprot id: Q5LN57
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

246200:SPO RS03015
gene id: 246200:SPO_RS03015
uniprot id: Q5LVU8
names: Similarity
messages: Belongs to the universal stress protein A family.

246200:SPO RS21055
gene id: 246200:SPO_RS21055
uniprot id: Q5LKY5
names: Similarity
messages: Belongs to the DapA family.

246200:SPO RS14590
gene id: 246200:SPO_RS14590
uniprot id: Q5LPH4
names: Function
messages: Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A.

246200:SPO RS14680
gene id: 246200:SPO_RS14680
uniprot id: Q5LPF5
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

246200:SPO RS02820
gene id: 246200:SPO_RS02820
uniprot id: Q5LVY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

246200:SPO RS02830
gene id: 246200:SPO_RS02830
uniprot id: V5UZC4
names: Subcellular Location Annotation
messages: Cell inner membrane

246200:SPO RS08005
gene id: 246200:SPO_RS08005
uniprot id: Q5LT41
names: Function
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

246200:SPO RS16235
gene id: 246200:SPO_RS16235
uniprot id: Q5LNJ9
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

246200:SPO RS15320
gene id: 246200:SPO_RS15320
uniprot id: Q5LP30
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

246200:SPO RS03545
gene id: 246200:SPO_RS03545
uniprot id: Q5LVJ9
names: Subcellular Location Annotation
messages: Cell inner membrane

246200:SPO RS06045
gene id: 246200:SPO_RS06045
uniprot id: Q5LU65
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

246200:SPO RS00880
gene id: 246200:SPO_RS00880
uniprot id: Q3V7J5
names: Similarity
messages: Belongs to the type III secretion exporter family.

246200:SPO RS17215
gene id: 246200:SPO_RS17215
uniprot id: Q5LN12
names: Similarity
messages: Belongs to the GcvT family.

246200:SPO RS02105
gene id: 246200:SPO_RS02105
uniprot id: Q5LWC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

246200:SPO RS15835
gene id: 246200:SPO_RS15835
uniprot id: Q5LNS8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

246200:SPO RS00515
gene id: 246200:SPO_RS00515
uniprot id: Q5LWP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

246200:SPO RS06310
gene id: 246200:SPO_RS06310
uniprot id: Q5LU20
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

246200:SPO RS15375
gene id: 246200:SPO_RS15375
uniprot id: Q5LP19
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

246200:SPO RS15860
gene id: 246200:SPO_RS15860
uniprot id: Q5LNS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

246200:SPO RS08580
gene id: 246200:SPO_RS08580
uniprot id: Q5LSS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

246200:SPO RS19035
gene id: 246200:SPO_RS19035
uniprot id: Q5LM13
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

246200:SPO RS06115
gene id: 246200:SPO_RS06115
uniprot id: Q5LU53
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

246200:SPO RS11420
gene id: 246200:SPO_RS11420
uniprot id: Q5LR78
names: Similarity
messages: Belongs to the peptidase C40 family.

246200:SPO RS07080
gene id: 246200:SPO_RS07080
uniprot id: Q5LTM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

246200:SPO RS21280
gene id: 246200:SPO_RS21280
uniprot id: Q5LKU1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

246200:SPO RS22005
gene id: 246200:SPO_RS22005
uniprot id: Q5LKF1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

246200:SPO RS06060
gene id: 246200:SPO_RS06060
uniprot id: Q5LU62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

246200:SPO RS12320
gene id: 246200:SPO_RS12320
uniprot id: Q5LQR3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

246200:SPO RS15585
gene id: 246200:SPO_RS15585
uniprot id: Q5LNX7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

246200:SPO RS19925
gene id: 246200:SPO_RS19925
uniprot id: Q5LLI9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

246200:SPO RS08960
gene id: 246200:SPO_RS08960
uniprot id: Q5LSK5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

246200:SPO RS08755
gene id: 246200:SPO_RS08755
uniprot id: Q5LSP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS01595
gene id: 246200:SPO_RS01595
uniprot id: Q5LXA4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

246200:SPO RS04025
gene id: 246200:SPO_RS04025
uniprot id: Q5LVA4
names: Similarity
messages: Belongs to the FMO family.

246200:SPO RS00660
gene id: 246200:SPO_RS00660
uniprot id: Q5LWS1
names: Similarity
messages: Belongs to the peptidase S58 family.

246200:SPO RS09440
gene id: 246200:SPO_RS09440
uniprot id: Q5LSB2
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS10645
gene id: 246200:SPO_RS10645
uniprot id: Q5LRM6
names: PTM
messages: Binds 1 heme group per subunit.

246200:SPO RS16680
gene id: 246200:SPO_RS16680
uniprot id: Q5LNB8
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS18140
gene id: 246200:SPO_RS18140
uniprot id: Q5LMI2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

246200:SPO RS00340
gene id: 246200:SPO_RS00340
uniprot id: Q5LWM6
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

246200:SPO RS17320
gene id: 246200:SPO_RS17320
uniprot id: Q5LMZ1
names: Similarity
messages: Belongs to the UPF0434 family.

246200:SPO RS03970
gene id: 246200:SPO_RS03970
uniprot id: Q5LVB5
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

246200:SPO RS09040
gene id: 246200:SPO_RS09040
uniprot id: Q5LSJ1
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

246200:SPO RS15560
gene id: 246200:SPO_RS15560
uniprot id: Q5LNY2
names: Similarity
messages: Belongs to the threonine synthase family.

246200:SPO RS08495
gene id: 246200:SPO_RS08495
uniprot id: Q5LSU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

246200:SPO RS05180
gene id: 246200:SPO_RS05180
uniprot id: Q5LUM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

246200:SPO RS04090
gene id: 246200:SPO_RS04090
uniprot id: Q5LV91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

246200:SPO RS06090
gene id: 246200:SPO_RS06090
uniprot id: Q5LU58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

246200:SPO RS00290
gene id: 246200:SPO_RS00290
uniprot id: Q5LWK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

246200:SPO RS13470
gene id: 246200:SPO_RS13470
uniprot id: Q5LQ41
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

246200:SPO RS17965
gene id: 246200:SPO_RS17965
uniprot id: Q5LML7
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS08170
gene id: 246200:SPO_RS08170
uniprot id: Q5LT08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

246200:SPO RS15430
gene id: 246200:SPO_RS15430
uniprot id: Q5LP08
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS00840
gene id: 246200:SPO_RS00840
uniprot id: Q5LWV7
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

246200:SPO RS19980
gene id: 246200:SPO_RS19980
uniprot id: Q5LLI6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

246200:SPO RS12100
gene id: 246200:SPO_RS12100
uniprot id: Q5LQV0
names: Similarity
messages: Belongs to the TPP enzyme family.

246200:SPO RS08585
gene id: 246200:SPO_RS08585
uniprot id: Q5LSS4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

246200:SPO RS10405
gene id: 246200:SPO_RS10405
uniprot id: Q5LRS4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

246200:SPO RS09195
gene id: 246200:SPO_RS09195
uniprot id: Q5LSG1
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

246200:SPO RS00320
gene id: 246200:SPO_RS00320
uniprot id: Q5LWL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

246200:SPO RS00310
gene id: 246200:SPO_RS00310
uniprot id: Q5LWL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

246200:SPO RS08175
gene id: 246200:SPO_RS08175
uniprot id: Q5LT07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS07950
gene id: 246200:SPO_RS07950
uniprot id: Q5LT52
names: Disruption Phenotype
names: Function
names: Similarity
messages: Catalyzes the conversion of trimethylamine N-oxide (TMAO) to dimethylamine (DMA) and formaldehyde.
messages: Disruption mutant cannot grow on TMAO or its upstream precursor trimethylamine (TMA) as a sole nitrogen source, although it can grow on dimethylamine (DMA) and monomethylamine (MMA).
messages: In the C-terminal section; belongs to the GcvT family.

246200:SPO RS09745
gene id: 246200:SPO_RS09745
uniprot id: Q5LS50
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

246200:SPO RS06150
gene id: 246200:SPO_RS06150
uniprot id: Q5LU46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

246200:SPO RS01790
gene id: 246200:SPO_RS01790
uniprot id: Q5LXD8
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

246200:SPO RS19575
gene id: 246200:SPO_RS19575
uniprot id: Q5LLR4
names: Subcellular Location Annotation
messages: Nucleus

246200:SPO RS18865
gene id: 246200:SPO_RS18865
uniprot id: Q5LM47
names: Similarity
messages: Belongs to the peptidase M17 family.

246200:SPO RS02130
gene id: 246200:SPO_RS02130
uniprot id: Q5LWC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

246200:SPO RS06660
gene id: 246200:SPO_RS06660
uniprot id: Q5LTV5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

246200:SPO RS19570
gene id: 246200:SPO_RS19570
uniprot id: Q5LLR5
names: Similarity
messages: Belongs to the YciI family.

246200:SPO RS09825
gene id: 246200:SPO_RS09825
uniprot id: Q5LS35
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS11040
gene id: 246200:SPO_RS11040
uniprot id: Q5LRF2
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

246200:SPO RS21330
gene id: 246200:SPO_RS21330
uniprot id: Q5LKT1
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS16305
gene id: 246200:SPO_RS16305
uniprot id: Q5LNI5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

246200:SPO RS17800
gene id: 246200:SPO_RS17800
uniprot id: Q5LMP9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

246200:SPO RS18225
gene id: 246200:SPO_RS18225
uniprot id: Q5LMG5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

246200:SPO RS03205
gene id: 246200:SPO_RS03205
uniprot id: Q5LVR7
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

246200:SPO RS15505
gene id: 246200:SPO_RS15505
uniprot id: Q5LNZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

246200:SPO RS11155
gene id: 246200:SPO_RS11155
uniprot id: Q5LRC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

246200:SPO RS14985
gene id: 246200:SPO_RS14985
uniprot id: Q5LP93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

246200:SPO RS00115
gene id: 246200:SPO_RS00115
uniprot id: Q5LWH8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

246200:SPO RS14695
gene id: 246200:SPO_RS14695
uniprot id: Q5LPF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

246200:SPO RS21335
gene id: 246200:SPO_RS21335
uniprot id: Q5LKT0
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS13540
gene id: 246200:SPO_RS13540
uniprot id: Q5LQ27
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

246200:SPO RS09710
gene id: 246200:SPO_RS09710
uniprot id: Q5LS57
names: Disruption Phenotype
names: Function
names: Induction
names: Miscellaneous
names: Similarity
messages: Belongs to the GcvT family. DmdA subfamily.
messages: By dimethylsulfonioproprionate (DMSP) and acrylate.
messages: DMSP is used as an intracellular osmolyte, predator deterrent and antioxidant.
messages: Involved in the assimilation of dimethylsulphoniopropionate (DMSP), an important compound in the fixation of carbon in marine phytoplankton, by mediating demethylation of dimethylsulfonioproprionate (DMSP) to methyl-mercaptopropionate (MMPA). The intracellular concentration of DMSP is estimated to be 70 mM.
messages: Loss of DMSP demethylation to MMPA. 25-fold increased sensitivity to acrylate, growth is strongly inhibited by 20 mM dimethylsulfonioproprionate (DMSP). Disruption of this gene has a polar effect on acuI, the downstream gene, which accounts for the increased sensitivity. Dimethyl sulfide (DMS) production is enhanced.

246200:SPO RS19455
gene id: 246200:SPO_RS19455
uniprot id: Q5LLT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

246200:SPO RS04675
gene id: 246200:SPO_RS04675
uniprot id: Q5LUX3
names: Similarity
messages: Belongs to the MT-A70-like family.

246200:SPO RS02210
gene id: 246200:SPO_RS02210
uniprot id: Q5LWA5
names: Subcellular Location Annotation
messages: Cytoplasm

246200:SPO RS02705
gene id: 246200:SPO_RS02705
uniprot id: Q5LW07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

246200:SPO RS03280
gene id: 246200:SPO_RS03280
uniprot id: Q5LVQ1
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS17460
gene id: 246200:SPO_RS17460
uniprot id: Q5LMW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

246200:SPO RS03075
gene id: 246200:SPO_RS03075
uniprot id: Q5LVT6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

246200:SPO RS05860
gene id: 246200:SPO_RS05860
uniprot id: Q5LU99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

246200:SPO RS03550
gene id: 246200:SPO_RS03550
uniprot id: Q5LVJ8
names: Subcellular Location Annotation
messages: Cell inner membrane

246200:SPO RS21295
gene id: 246200:SPO_RS21295
uniprot id: Q5LKT8
names: Function
messages: Acts on leucine, isoleucine and valine.

246200:SPO RS16210
gene id: 246200:SPO_RS16210
uniprot id: Q5LNK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

246200:SPO RS14195
gene id: 246200:SPO_RS14195
uniprot id: Q5LPQ3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

246200:SPO RS03410
gene id: 246200:SPO_RS03410
uniprot id: Q5LVM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (TauB), two transmembrane proteins (TauC) and a solute-binding protein (TauA).

246200:SPO RS08900
gene id: 246200:SPO_RS08900
uniprot id: Q5LSL8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

246200:SPO RS17875
gene id: 246200:SPO_RS17875
uniprot id: Q5LMN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

246200:SPO RS19790
gene id: 246200:SPO_RS19790
uniprot id: Q5LLM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

246200:SPO RS07650
gene id: 246200:SPO_RS07650
uniprot id: Q5LTB2
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

246200:SPO RS07265
gene id: 246200:SPO_RS07265
uniprot id: Q5LTJ0
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

246200:SPO RS18415
gene id: 246200:SPO_RS18415
uniprot id: Q5LMC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

246200:SPO RS21520
gene id: 246200:SPO_RS21520
uniprot id: Q5LKP9
names: Similarity
messages: Belongs to the IlvD/Edd family.

246200:SPO RS10920
gene id: 246200:SPO_RS10920
uniprot id: Q5LRH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

246200:SPO RS07995
gene id: 246200:SPO_RS07995
uniprot id: Q5LT43
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

246200:SPO RS05810
gene id: 246200:SPO_RS05810
uniprot id: Q5LUA9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system UehABC, which imports both ectoine and 5-hydroxyectoine as nutrients, and not as osmoprotectants.
messages: The complex comprises the extracytoplasmic solute receptor protein UehA, and the two transmembrane proteins UehB and UehC.
messages: Transport is enhanced in cells that are grown in the presence of ectoine, but not by high-salinity media.

246200:SPO RS21180
gene id: 246200:SPO_RS21180
uniprot id: Q5LKW0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenium-binding protein family.
messages: Catalyzes the oxidation of methanethiol.
messages: Induced by methanethiol, dimethylsulfoniopropionate (DMSP) and methylmercaptopropionic acid (MMPA).
messages: Periplasm

246200:SPO RS18740
gene id: 246200:SPO_RS18740
uniprot id: Q5LM70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS20350
gene id: 246200:SPO_RS20350
uniprot id: Q5LLC1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS17595
gene id: 246200:SPO_RS17595
uniprot id: Q5LMT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS05510
gene id: 246200:SPO_RS05510
uniprot id: Q5LUG8
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

246200:SPO RS04650
gene id: 246200:SPO_RS04650
uniprot id: Q5LUX9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

246200:SPO RS21790
gene id: 246200:SPO_RS21790
uniprot id: Q5LKJ5
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

246200:SPO RS08145
gene id: 246200:SPO_RS08145
uniprot id: Q5LT13
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

246200:SPO RS02255
gene id: 246200:SPO_RS02255
uniprot id: Q5LW96
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

246200:SPO RS07955
gene id: 246200:SPO_RS07955
uniprot id: Q5LT51
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

246200:SPO RS19910
gene id: 246200:SPO_RS19910
uniprot id: Q5LLJ2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

246200:SPO RS21155
gene id: 246200:SPO_RS21155
uniprot id: Q5LKW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS11250
gene id: 246200:SPO_RS11250
uniprot id: Q5LRB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

246200:SPO RS09915
gene id: 246200:SPO_RS09915
uniprot id: Q5LS17
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

246200:SPO RS15055
gene id: 246200:SPO_RS15055
uniprot id: Q5LP79
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

246200:SPO RS01210
gene id: 246200:SPO_RS01210
uniprot id: Q5LX21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

246200:SPO RS16110
gene id: 246200:SPO_RS16110
uniprot id: Q5LNM3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

246200:SPO RS10880
gene id: 246200:SPO_RS10880
uniprot id: Q5LRI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

246200:SPO RS07455
gene id: 246200:SPO_RS07455
uniprot id: Q5LTF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS10390
gene id: 246200:SPO_RS10390
uniprot id: Q5LRS7
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

246200:SPO RS18190
gene id: 246200:SPO_RS18190
uniprot id: Q5LMH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

246200:SPO RS09905
gene id: 246200:SPO_RS09905
uniprot id: Q5LS19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

246200:SPO RS10415
gene id: 246200:SPO_RS10415
uniprot id: Q5LRS2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

246200:SPO RS13465
gene id: 246200:SPO_RS13465
uniprot id: Q5LQ42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

246200:SPO RS05050
gene id: 246200:SPO_RS05050
uniprot id: Q5LUQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

246200:SPO RS17020
gene id: 246200:SPO_RS17020
uniprot id: Q5LN52
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

246200:SPO RS05130
gene id: 246200:SPO_RS05130
uniprot id: Q5LUN4
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS20675
gene id: 246200:SPO_RS20675
uniprot id: Q5LL60
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

246200:SPO RS09100
gene id: 246200:SPO_RS09100
uniprot id: Q5LSH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS15445
gene id: 246200:SPO_RS15445
uniprot id: Q5LP05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS16380
gene id: 246200:SPO_RS16380
uniprot id: Q5LNH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

246200:SPO RS01910
gene id: 246200:SPO_RS01910
uniprot id: Q5LXG4
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS14320
gene id: 246200:SPO_RS14320
uniprot id: Q5LPM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

246200:SPO RS04315
gene id: 246200:SPO_RS04315
uniprot id: Q5LV46
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

246200:SPO RS01015
gene id: 246200:SPO_RS01015
uniprot id: Q5LWY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

246200:SPO RS00920
gene id: 246200:SPO_RS00920
uniprot id: Q5LWX3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

246200:SPO RS19140
gene id: 246200:SPO_RS19140
uniprot id: Q5LLZ3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

246200:SPO RS15035
gene id: 246200:SPO_RS15035
uniprot id: Q5LP83
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

246200:SPO RS21255
gene id: 246200:SPO_RS21255
uniprot id: Q5LKU6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

246200:SPO RS04310
gene id: 246200:SPO_RS04310
uniprot id: Q5LV47
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

246200:SPO RS11965
gene id: 246200:SPO_RS11965
uniprot id: Q5LQX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

246200:SPO RS16180
gene id: 246200:SPO_RS16180
uniprot id: Q5LNK9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

246200:SPO RS08100
gene id: 246200:SPO_RS08100
uniprot id: Q5LT22
names: Similarity
messages: Belongs to the GcvT family.

246200:SPO RS14840
gene id: 246200:SPO_RS14840
uniprot id: Q5LPC2
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

246200:SPO RS16270
gene id: 246200:SPO_RS16270
uniprot id: Q5LNJ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

246200:SPO RS14785
gene id: 246200:SPO_RS14785
uniprot id: Q5LPD3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

246200:SPO RS09125
gene id: 246200:SPO_RS09125
uniprot id: Q5LSH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Cell membrane
messages: Membrane

246200:SPO RS11120
gene id: 246200:SPO_RS11120
uniprot id: Q5LRD6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

246200:SPO RS04045
gene id: 246200:SPO_RS04045
uniprot id: Q5LVA0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

246200:SPO RS15555
gene id: 246200:SPO_RS15555
uniprot id: Q5LNY3
names: Similarity
messages: Belongs to the peptidase M16 family.

246200:SPO RS16200
gene id: 246200:SPO_RS16200
uniprot id: Q5LNK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

246200:SPO RS10800
gene id: 246200:SPO_RS10800
uniprot id: Q5LRJ7
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

246200:SPO RS16410
gene id: 246200:SPO_RS16410
uniprot id: Q5LNG5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS20650
gene id: 246200:SPO_RS20650
uniprot id: Q5LL65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

246200:SPO RS01860
gene id: 246200:SPO_RS01860
uniprot id: Q5LXF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

246200:SPO RS01350
gene id: 246200:SPO_RS01350
uniprot id: Q5LX43
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS18980
gene id: 246200:SPO_RS18980
uniprot id: Q5LM24
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

246200:SPO RS06510
gene id: 246200:SPO_RS06510
uniprot id: Q5LTY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

246200:SPO RS09645
gene id: 246200:SPO_RS09645
uniprot id: Q5LS70
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

246200:SPO RS17815
gene id: 246200:SPO_RS17815
uniprot id: Q5LMP7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

246200:SPO RS22050
gene id: 246200:SPO_RS22050
uniprot id: Q5LKE2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

246200:SPO RS05635
gene id: 246200:SPO_RS05635
uniprot id: Q5LUE4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS16495
gene id: 246200:SPO_RS16495
uniprot id: Q5LNE8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

246200:SPO RS11005
gene id: 246200:SPO_RS11005
uniprot id: Q5LRF7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS07150
gene id: 246200:SPO_RS07150
uniprot id: Q5LTL3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS19200
gene id: 246200:SPO_RS19200
uniprot id: Q5LLY2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

246200:SPO RS11925
gene id: 246200:SPO_RS11925
uniprot id: Q5LQY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

246200:SPO RS08270
gene id: 246200:SPO_RS08270
uniprot id: Q5LSY8
names: Subcellular Location Annotation
messages: Secreted

246200:SPO RS06825
gene id: 246200:SPO_RS06825
uniprot id: Q5LTS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

246200:SPO RS20355
gene id: 246200:SPO_RS20355
uniprot id: Q5LLC0
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS19370
gene id: 246200:SPO_RS19370
uniprot id: Q5LLV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

246200:SPO RS04345
gene id: 246200:SPO_RS04345
uniprot id: Q5LV40
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS08310
gene id: 246200:SPO_RS08310
uniprot id: Q5LSY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

246200:SPO RS08125
gene id: 246200:SPO_RS08125
uniprot id: Q5LT17
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS08280
gene id: 246200:SPO_RS08280
uniprot id: Q5LSY6
names: Similarity
messages: Belongs to the GcvT family.

246200:SPO RS21745
gene id: 246200:SPO_RS21745
uniprot id: Q5LKK4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

246200:SPO RS05520
gene id: 246200:SPO_RS05520
uniprot id: Q5LUG6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

246200:SPO RS16005
gene id: 246200:SPO_RS16005
uniprot id: Q5LNP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

246200:SPO RS09535
gene id: 246200:SPO_RS09535
uniprot id: Q5LS92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

246200:SPO RS17090
gene id: 246200:SPO_RS17090
uniprot id: Q5LN38
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

246200:SPO RS07355
gene id: 246200:SPO_RS07355
uniprot id: Q5LTH1
names: Similarity
messages: Belongs to the DEAD box helicase family.

246200:SPO RS21530
gene id: 246200:SPO_RS21530
uniprot id: Q5LKP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS02515
gene id: 246200:SPO_RS02515
uniprot id: Q5LW45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

246200:SPO RS08185
gene id: 246200:SPO_RS08185
uniprot id: Q5LT05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

246200:SPO RS16485
gene id: 246200:SPO_RS16485
uniprot id: Q5LNF0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

246200:SPO RS00140
gene id: 246200:SPO_RS00140
uniprot id: Q5LWH3
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS10985
gene id: 246200:SPO_RS10985
uniprot id: Q5LRG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

246200:SPO RS16035
gene id: 246200:SPO_RS16035
uniprot id: Q5LNN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

246200:SPO RS03920
gene id: 246200:SPO_RS03920
uniprot id: Q5LVC5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

246200:SPO RS11270
gene id: 246200:SPO_RS11270
uniprot id: Q5LRA7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

246200:SPO RS19085
gene id: 246200:SPO_RS19085
uniprot id: Q5LM03
names: Similarity
messages: Belongs to the SfsA family.

246200:SPO RS01100
gene id: 246200:SPO_RS01100
uniprot id: Q5LX06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

246200:SPO RS04015
gene id: 246200:SPO_RS04015
uniprot id: Q5LVA6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

246200:SPO RS13920
gene id: 246200:SPO_RS13920
uniprot id: Q5LPV9
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

246200:SPO RS11630
gene id: 246200:SPO_RS11630
uniprot id: Q5LR38
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

246200:SPO RS00985
gene id: 246200:SPO_RS00985
uniprot id: Q5LWZ4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

246200:SPO RS19460
gene id: 246200:SPO_RS19460
uniprot id: Q5LLT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

246200:SPO RS13890
gene id: 246200:SPO_RS13890
uniprot id: Q5LPW4
names: Similarity
messages: Belongs to the HsdR family.

246200:SPO RS00500
gene id: 246200:SPO_RS00500
uniprot id: Q5LWP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS03735
gene id: 246200:SPO_RS03735
uniprot id: Q5LVG2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

246200:SPO RS19990
gene id: 246200:SPO_RS19990
uniprot id: Q5LLI4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

246200:SPO RS08735
gene id: 246200:SPO_RS08735
uniprot id: Q5LSP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

246200:SPO RS10095
gene id: 246200:SPO_RS10095
uniprot id: Q5LRY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

246200:SPO RS16230
gene id: 246200:SPO_RS16230
uniprot id: Q5LNK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

246200:SPO RS19210
gene id: 246200:SPO_RS19210
uniprot id: Q5LLY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS20125
gene id: 246200:SPO_RS20125
uniprot id: Q5LLF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS03465
gene id: 246200:SPO_RS03465
uniprot id: Q5LVL4
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

246200:SPO RS10855
gene id: 246200:SPO_RS10855
uniprot id: Q5LRI7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

246200:SPO RS21260
gene id: 246200:SPO_RS21260
uniprot id: Q5LKU5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS06720
gene id: 246200:SPO_RS06720
uniprot id: Q5LTU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

246200:SPO RS21580
gene id: 246200:SPO_RS21580
uniprot id: Q5LKN7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS19750
gene id: 246200:SPO_RS19750
uniprot id: Q5LLN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

246200:SPO RS09175
gene id: 246200:SPO_RS09175
uniprot id: Q5LSG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

246200:SPO RS01630
gene id: 246200:SPO_RS01630
uniprot id: Q5LX97
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

246200:SPO RS13580
gene id: 246200:SPO_RS13580
uniprot id: Q5LQ19
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

246200:SPO RS03930
gene id: 246200:SPO_RS03930
uniprot id: Q5LVC3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

246200:SPO RS04405
gene id: 246200:SPO_RS04405
uniprot id: Q5LV28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

246200:SPO RS11595
gene id: 246200:SPO_RS11595
uniprot id: Q5LR44
names: Similarity
messages: Belongs to the autoinducer synthase family.

246200:SPO RS05535
gene id: 246200:SPO_RS05535
uniprot id: Q5LUG3
names: Similarity
messages: Belongs to the YciI family.

246200:SPO RS14380
gene id: 246200:SPO_RS14380
uniprot id: Q5LPL7
names: Subcellular Location Annotation
messages: Cell inner membrane

246200:SPO RS13645
gene id: 246200:SPO_RS13645
uniprot id: Q5LQ06
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

246200:SPO RS07130
gene id: 246200:SPO_RS07130
uniprot id: Q5LTL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

246200:SPO RS22310
gene id: 246200:SPO_RS22310
uniprot id: Q5LN17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

246200:SPO RS07655
gene id: 246200:SPO_RS07655
uniprot id: Q5LTB1
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm, in association with PQQ biosynthesis, but is not absolutely required for this synthesis.

246200:SPO RS01510
gene id: 246200:SPO_RS01510
uniprot id: Q5LX83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

246200:SPO RS17180
gene id: 246200:SPO_RS17180
uniprot id: Q5LN20
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

246200:SPO RS08460
gene id: 246200:SPO_RS08460
uniprot id: Q5LSV1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

246200:SPO RS12700
gene id: 246200:SPO_RS12700
uniprot id: Q5LQI8
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

246200:SPO RS16870
gene id: 246200:SPO_RS16870
uniprot id: Q5LN82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

246200:SPO RS10830
gene id: 246200:SPO_RS10830
uniprot id: Q5LRJ1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

246200:SPO RS13325
gene id: 246200:SPO_RS13325
uniprot id: Q5LQ69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS15135
gene id: 246200:SPO_RS15135
uniprot id: Q5LP64
names: Similarity
messages: Belongs to the TelA family.

246200:SPO RS14465
gene id: 246200:SPO_RS14465
uniprot id: Q5LPJ9
names: Similarity
messages: Belongs to the BolA/IbaG family.

246200:SPO RS16215
gene id: 246200:SPO_RS16215
uniprot id: Q3V7J3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

246200:SPO RS01690
gene id: 246200:SPO_RS01690
uniprot id: Q5LXC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

246200:SPO RS05890
gene id: 246200:SPO_RS05890
uniprot id: Q5LU93
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

246200:SPO RS07890
gene id: 246200:SPO_RS07890
uniprot id: Q5LT64
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Expression is induced by TMAO.
messages: Part of the ABC transporter complex TmoXWV involved in trimethylamine N-oxide (TMAO) import (PubMed:24550299). Responsible for the translocation of the substrate across the membrane (Probable). Is specific for TMAO and essential for TMAO metabolism (PubMed:24550299).
messages: The complex is probably composed of two ATP-binding proteins (TmoW), two transmembrane proteins (TmoV) and a solute-binding protein (TmoX).

246200:SPO RS04570
gene id: 246200:SPO_RS04570
uniprot id: Q5LUZ5
names: Subcellular Location Annotation
messages: Mitochondrion

246200:SPO RS14190
gene id: 246200:SPO_RS14190
uniprot id: Q5LPQ5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

246200:SPO RS02530
gene id: 246200:SPO_RS02530
uniprot id: Q5LW42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

246200:SPO RS18435
gene id: 246200:SPO_RS18435
uniprot id: Q5LMC5
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS17580
gene id: 246200:SPO_RS17580
uniprot id: Q5LMU1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS05540
gene id: 246200:SPO_RS05540
uniprot id: Q5LUG2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS02125
gene id: 246200:SPO_RS02125
uniprot id: Q5LWC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

246200:SPO RS10335
gene id: 246200:SPO_RS10335
uniprot id: Q5LRT7
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

246200:SPO RS02540
gene id: 246200:SPO_RS02540
uniprot id: Q5LW40
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

246200:SPO RS04205
gene id: 246200:SPO_RS04205
uniprot id: Q5LV68
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

246200:SPO RS16135
gene id: 246200:SPO_RS16135
uniprot id: Q5LNL8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS01380
gene id: 246200:SPO_RS01380
uniprot id: Q5LX56
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

246200:SPO RS14370
gene id: 246200:SPO_RS14370
uniprot id: Q5LPL9
names: Similarity
messages: Belongs to the peptidase C69 family.

246200:SPO RS10560
gene id: 246200:SPO_RS10560
uniprot id: Q5LRP3
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS17885
gene id: 246200:SPO_RS17885
uniprot id: Q5LMN3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS08555
gene id: 246200:SPO_RS08555
uniprot id: Q5LST0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

246200:SPO RS14550
gene id: 246200:SPO_RS14550
uniprot id: Q5LPI2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

246200:SPO RS00505
gene id: 246200:SPO_RS00505
uniprot id: Q5LWP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

246200:SPO RS13210
gene id: 246200:SPO_RS13210
uniprot id: Q5LQ91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS19375
gene id: 246200:SPO_RS19375
uniprot id: Q5LLV3
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

246200:SPO RS06995
gene id: 246200:SPO_RS06995
uniprot id: Q5LTP2
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

246200:SPO RS01940
gene id: 246200:SPO_RS01940
uniprot id: Q5LXG9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

246200:SPO RS13670
gene id: 246200:SPO_RS13670
uniprot id: Q5LQ01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

246200:SPO RS20635
gene id: 246200:SPO_RS20635
uniprot id: Q5LL68
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS20560
gene id: 246200:SPO_RS20560
uniprot id: Q5LL83
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS06580
gene id: 246200:SPO_RS06580
uniprot id: Q5LTW8
names: Subcellular Location Annotation
messages: Cytoplasm

246200:SPO RS18815
gene id: 246200:SPO_RS18815
uniprot id: Q5LM55
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS12080
gene id: 246200:SPO_RS12080
uniprot id: Q5LQV4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS05655
gene id: 246200:SPO_RS05655
uniprot id: Q5LUE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS09500
gene id: 246200:SPO_RS09500
uniprot id: Q5LS99
names: Similarity
messages: Belongs to the BolA/IbaG family.

246200:SPO RS14055
gene id: 246200:SPO_RS14055
uniprot id: Q5LPT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

246200:SPO RS19705
gene id: 246200:SPO_RS19705
uniprot id: Q5LLP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

246200:SPO RS01660
gene id: 246200:SPO_RS01660
uniprot id: Q5LXA8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

246200:SPO RS17700
gene id: 246200:SPO_RS17700
uniprot id: Q5LMR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

246200:SPO RS19935
gene id: 246200:SPO_RS19935
uniprot id: Q5LLL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

246200:SPO RS14150
gene id: 246200:SPO_RS14150
uniprot id: Q5LPR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

246200:SPO RS15200
gene id: 246200:SPO_RS15200
uniprot id: Q5LP52
names: Subcellular Location Annotation
messages: Cell inner membrane

246200:SPO RS06015
gene id: 246200:SPO_RS06015
uniprot id: Q5LU71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

246200:SPO RS14160
gene id: 246200:SPO_RS14160
uniprot id: Q5LPR1
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

246200:SPO RS08550
gene id: 246200:SPO_RS08550
uniprot id: Q5LST1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

246200:SPO RS21875
gene id: 246200:SPO_RS21875
uniprot id: Q5LKH8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

246200:SPO RS16490
gene id: 246200:SPO_RS16490
uniprot id: Q5LNE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

246200:SPO RS18045
gene id: 246200:SPO_RS18045
uniprot id: Q5LMK1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS15850
gene id: 246200:SPO_RS15850
uniprot id: Q5LNS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

246200:SPO RS14225
gene id: 246200:SPO_RS14225
uniprot id: Q5LPP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

246200:SPO RS19660
gene id: 246200:SPO_RS19660
uniprot id: Q5LLP8
names: Similarity
messages: Belongs to the thioredoxin family.

246200:SPO RS02550
gene id: 246200:SPO_RS02550
uniprot id: Q5LW38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

246200:SPO RS11800
gene id: 246200:SPO_RS11800
uniprot id: Q5LR04
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

246200:SPO RS08490
gene id: 246200:SPO_RS08490
uniprot id: Q5LSU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

246200:SPO RS17645
gene id: 246200:SPO_RS17645
uniprot id: Q5LMS8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

246200:SPO RS07855
gene id: 246200:SPO_RS07855
uniprot id: Q5LT71
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

246200:SPO RS19180
gene id: 246200:SPO_RS19180
uniprot id: Q5LLY6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS08705
gene id: 246200:SPO_RS08705
uniprot id: Q5LSQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

246200:SPO RS13195
gene id: 246200:SPO_RS13195
uniprot id: Q5LQ94
names: Similarity
messages: Belongs to the pirin family.

246200:SPO RS16950
gene id: 246200:SPO_RS16950
uniprot id: Q5LN66
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

246200:SPO RS00245
gene id: 246200:SPO_RS00245
uniprot id: Q5LWJ0
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.

246200:SPO RS04430
gene id: 246200:SPO_RS04430
uniprot id: Q5LV24
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

246200:SPO RS06880
gene id: 246200:SPO_RS06880
uniprot id: Q5LTR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

246200:SPO RS06120
gene id: 246200:SPO_RS06120
uniprot id: Q5LU52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

246200:SPO RS09060
gene id: 246200:SPO_RS09060
uniprot id: Q5LSI7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

246200:SPO RS00425
gene id: 246200:SPO_RS00425
uniprot id: Q5LWM7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

246200:SPO RS03745
gene id: 246200:SPO_RS03745
uniprot id: Q5LVG0
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

246200:SPO RS10930
gene id: 246200:SPO_RS10930
uniprot id: Q5LRH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

246200:SPO RS18385
gene id: 246200:SPO_RS18385
uniprot id: Q5LMD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

246200:SPO RS09495
gene id: 246200:SPO_RS09495
uniprot id: Q5LSA0
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

246200:SPO RS03630
gene id: 246200:SPO_RS03630
uniprot id: Q5LVI2
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

246200:SPO RS14690
gene id: 246200:SPO_RS14690
uniprot id: Q5LPF3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

246200:SPO RS18790
gene id: 246200:SPO_RS18790
uniprot id: Q5LM60
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

246200:SPO RS05690
gene id: 246200:SPO_RS05690
uniprot id: Q5LUD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Cytoplasm
messages: Homodimer.

246200:SPO RS08915
gene id: 246200:SPO_RS08915
uniprot id: Q5LSL5
names: Similarity
messages: Belongs to the UPF0047 family.

246200:SPO RS15790
gene id: 246200:SPO_RS15790
uniprot id: Q5LNT7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

246200:SPO RS09655
gene id: 246200:SPO_RS09655
uniprot id: Q5LS68
names: Similarity
messages: Belongs to the YciI family.

246200:SPO RS16140
gene id: 246200:SPO_RS16140
uniprot id: Q5LNL7
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS10065
gene id: 246200:SPO_RS10065
uniprot id: Q5LRY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

246200:SPO RS04600
gene id: 246200:SPO_RS04600
uniprot id: Q5LUY9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

246200:SPO RS17040
gene id: 246200:SPO_RS17040
uniprot id: Q5LN48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

246200:SPO RS13970
gene id: 246200:SPO_RS13970
uniprot id: Q5LPU9
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

246200:SPO RS09925
gene id: 246200:SPO_RS09925
uniprot id: Q5LS15
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

246200:SPO RS09275
gene id: 246200:SPO_RS09275
uniprot id: Q5LSE5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

246200:SPO RS15570
gene id: 246200:SPO_RS15570
uniprot id: Q5LNY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

246200:SPO RS08825
gene id: 246200:SPO_RS08825
uniprot id: Q5LSN3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

246200:SPO RS05100
gene id: 246200:SPO_RS05100
uniprot id: Q5LUP0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

246200:SPO RS17715
gene id: 246200:SPO_RS17715
uniprot id: Q5LMR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

246200:SPO RS02035
gene id: 246200:SPO_RS02035
uniprot id: Q5LWE0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

246200:SPO RS10900
gene id: 246200:SPO_RS10900
uniprot id: Q5LRH8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

246200:SPO RS20580
gene id: 246200:SPO_RS20580
uniprot id: Q5LL79
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS17690
gene id: 246200:SPO_RS17690
uniprot id: Q5LMR9
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS11565
gene id: 246200:SPO_RS11565
uniprot id: Q5LR50
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

246200:SPO RS17030
gene id: 246200:SPO_RS17030
uniprot id: Q5LN50
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

246200:SPO RS18405
gene id: 246200:SPO_RS18405
uniprot id: Q5LMD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

246200:SPO RS17865
gene id: 246200:SPO_RS17865
uniprot id: Q5LMN7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

246200:SPO RS14640
gene id: 246200:SPO_RS14640
uniprot id: Q5LPG3
names: Similarity
messages: Belongs to the TPP enzyme family.

246200:SPO RS15115
gene id: 246200:SPO_RS15115
uniprot id: Q5LP68
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

246200:SPO RS02270
gene id: 246200:SPO_RS02270
uniprot id: Q5LW93
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

246200:SPO RS07925
gene id: 246200:SPO_RS07925
uniprot id: Q5LNV0
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

246200:SPO RS06265
gene id: 246200:SPO_RS06265
uniprot id: Q5LU26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

246200:SPO RS03200
gene id: 246200:SPO_RS03200
uniprot id: Q5LVR8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

246200:SPO RS01070
gene id: 246200:SPO_RS01070
uniprot id: Q5LWZ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

246200:SPO RS16115
gene id: 246200:SPO_RS16115
uniprot id: Q5LNM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

246200:SPO RS15265
gene id: 246200:SPO_RS15265
uniprot id: Q5LP41
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS14325
gene id: 246200:SPO_RS14325
uniprot id: Q5LPM8
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

246200:SPO RS20080
gene id: 246200:SPO_RS20080
uniprot id: Q5LLG6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

246200:SPO RS10995
gene id: 246200:SPO_RS10995
uniprot id: Q5LRF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

246200:SPO RS11755
gene id: 246200:SPO_RS11755
uniprot id: Q5LR13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

246200:SPO RS17205
gene id: 246200:SPO_RS17205
uniprot id: Q5LN14
names: Cofactor
messages: Binds 1 zinc ion per subunit.

246200:SPO RS04010
gene id: 246200:SPO_RS04010
uniprot id: Q5LVA7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

246200:SPO RS21230
gene id: 246200:SPO_RS21230
uniprot id: Q5LKV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS09940
gene id: 246200:SPO_RS09940
uniprot id: Q5LS12
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

246200:SPO RS17070
gene id: 246200:SPO_RS17070
uniprot id: Q5LN42
names: Similarity
messages: Belongs to the peptidase M16 family.

246200:SPO RS16670
gene id: 246200:SPO_RS16670
uniprot id: Q5LNC0
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS02025
gene id: 246200:SPO_RS02025
uniprot id: Q5LWE2
names: Similarity
messages: Belongs to the UPF0102 family.

246200:SPO RS09345
gene id: 246200:SPO_RS09345
uniprot id: Q5LSD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS06970
gene id: 246200:SPO_RS06970
uniprot id: Q5LTP7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

246200:SPO RS19500
gene id: 246200:SPO_RS19500
uniprot id: Q5LLS8
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS08720
gene id: 246200:SPO_RS08720
uniprot id: Q5LSQ2
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

246200:SPO RS11635
gene id: 246200:SPO_RS11635
uniprot id: Q5LR37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

246200:SPO RS00795
gene id: 246200:SPO_RS00795
uniprot id: Q5LWU8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

246200:SPO RS04495
gene id: 246200:SPO_RS04495
uniprot id: Q5LV10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

246200:SPO RS03645
gene id: 246200:SPO_RS03645
uniprot id: Q5LVH9
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

246200:SPO RS10030
gene id: 246200:SPO_RS10030
uniprot id: Q5LRZ4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

246200:SPO RS09210
gene id: 246200:SPO_RS09210
uniprot id: Q5LSF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

246200:SPO RS15460
gene id: 246200:SPO_RS15460
uniprot id: Q5LP01
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

246200:SPO RS21780
gene id: 246200:SPO_RS21780
uniprot id: Q5LKJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS19310
gene id: 246200:SPO_RS19310
uniprot id: Q5LLW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

246200:SPO RS02020
gene id: 246200:SPO_RS02020
uniprot id: Q5LWE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

246200:SPO RS08710
gene id: 246200:SPO_RS08710
uniprot id: Q5LSQ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

246200:SPO RS10300
gene id: 246200:SPO_RS10300
uniprot id: Q5LRU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

246200:SPO RS19385
gene id: 246200:SPO_RS19385
uniprot id: Q5LLV1
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS02560
gene id: 246200:SPO_RS02560
uniprot id: Q5LW36
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

246200:SPO RS18810
gene id: 246200:SPO_RS18810
uniprot id: Q5LM56
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS19560
gene id: 246200:SPO_RS19560
uniprot id: Q5LLR7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

246200:SPO RS13490
gene id: 246200:SPO_RS13490
uniprot id: Q5LQ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

246200:SPO RS01390
gene id: 246200:SPO_RS01390
uniprot id: Q5LX54
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

246200:SPO RS10225
gene id: 246200:SPO_RS10225
uniprot id: Q5LRV8
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS01625
gene id: 246200:SPO_RS01625
uniprot id: Q5LX98
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

246200:SPO RS13735
gene id: 246200:SPO_RS13735
uniprot id: Q5LPY8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

246200:SPO RS20845
gene id: 246200:SPO_RS20845
uniprot id: Q5LL27
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

246200:SPO RS03030
gene id: 246200:SPO_RS03030
uniprot id: Q5LVU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

246200:SPO RS18825
gene id: 246200:SPO_RS18825
uniprot id: Q5LM53
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS12845
gene id: 246200:SPO_RS12845
uniprot id: Q5LQF9
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS08920
gene id: 246200:SPO_RS08920
uniprot id: Q5LSL4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

246200:SPO RS01855
gene id: 246200:SPO_RS01855
uniprot id: Q5LXG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

246200:SPO RS18080
gene id: 246200:SPO_RS18080
uniprot id: Q5LMJ4
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

246200:SPO RS02995
gene id: 246200:SPO_RS02995
uniprot id: Q5LVV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS09355
gene id: 246200:SPO_RS09355
uniprot id: Q5LSC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

246200:SPO RS11035
gene id: 246200:SPO_RS11035
uniprot id: Q5LRF3
names: Similarity
messages: Belongs to the histone deacetylase family.

246200:SPO RS01055
gene id: 246200:SPO_RS01055
uniprot id: Q5LWZ7
names: Similarity
messages: Belongs to the GcvT family.

246200:SPO RS15725
gene id: 246200:SPO_RS15725
uniprot id: Q5LNV0
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

246200:SPO RS04705
gene id: 246200:SPO_RS04705
uniprot id: Q5LUW5
names: Similarity
messages: Belongs to the UPF0235 family.

246200:SPO RS17795
gene id: 246200:SPO_RS17795
uniprot id: Q5LMQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

246200:SPO RS21755
gene id: 246200:SPO_RS21755
uniprot id: Q5LKK2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS20955
gene id: 246200:SPO_RS20955
uniprot id: Q5LL05
names: Similarity
messages: Belongs to the Ahb/Nir family.

246200:SPO RS17415
gene id: 246200:SPO_RS17415
uniprot id: Q5LMX2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

246200:SPO RS17765
gene id: 246200:SPO_RS17765
uniprot id: Q5LMQ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

246200:SPO RS17670
gene id: 246200:SPO_RS17670
uniprot id: Q5LMS3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

246200:SPO RS06885
gene id: 246200:SPO_RS06885
uniprot id: Q5LTR1
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

246200:SPO RS01650
gene id: 246200:SPO_RS01650
uniprot id: Q5LXB0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS21150
gene id: 246200:SPO_RS21150
uniprot id: Q5LKW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS09875
gene id: 246200:SPO_RS09875
uniprot id: Q5LS25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

246200:SPO RS21980
gene id: 246200:SPO_RS21980
uniprot id: Q5LKF6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

246200:SPO RS09540
gene id: 246200:SPO_RS09540
uniprot id: Q5LS91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

246200:SPO RS03900
gene id: 246200:SPO_RS03900
uniprot id: Q5LVC9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

246200:SPO RS12875
gene id: 246200:SPO_RS12875
uniprot id: Q5LQF2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

246200:SPO RS11325
gene id: 246200:SPO_RS11325
uniprot id: Q5LR96
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

246200:SPO RS01920
gene id: 246200:SPO_RS01920
uniprot id: Q5LXG2
names: Similarity
messages: Belongs to the BMP lipoprotein family.

246200:SPO RS10540
gene id: 246200:SPO_RS10540
uniprot id: Q5LRP7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

246200:SPO RS00765
gene id: 246200:SPO_RS00765
uniprot id: Q5LWV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

246200:SPO RS18515
gene id: 246200:SPO_RS18515
uniprot id: Q5LMB0
names: Subunit
messages: Homodimer.

246200:SPO RS01335
gene id: 246200:SPO_RS01335
uniprot id: Q5LX46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

246200:SPO RS11335
gene id: 246200:SPO_RS11335
uniprot id: Q5LR94
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

246200:SPO RS02815
gene id: 246200:SPO_RS02815
uniprot id: Q5LVY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

246200:SPO RS12990
gene id: 246200:SPO_RS12990
uniprot id: Q5LQD1
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

246200:SPO RS04295
gene id: 246200:SPO_RS04295
uniprot id: Q5LV50
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

246200:SPO RS10635
gene id: 246200:SPO_RS10635
uniprot id: Q5LRM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

246200:SPO RS00050
gene id: 246200:SPO_RS00050
uniprot id: Q5LWF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

246200:SPO RS19540
gene id: 246200:SPO_RS19540
uniprot id: Q5LLS1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

246200:SPO RS00580
gene id: 246200:SPO_RS00580
uniprot id: Q5LWR6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

246200:SPO RS09975
gene id: 246200:SPO_RS09975
uniprot id: Q5LS05
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

246200:SPO RS21195
gene id: 246200:SPO_RS21195
uniprot id: Q5LKV7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

246200:SPO RS11165
gene id: 246200:SPO_RS11165
uniprot id: Q5LRC7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS02675
gene id: 246200:SPO_RS02675
uniprot id: Q5LW13
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

246200:SPO RS02525
gene id: 246200:SPO_RS02525
uniprot id: Q5LW43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

246200:SPO RS00195
gene id: 246200:SPO_RS00195
uniprot id: Q5LWI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

246200:SPO RS08425
gene id: 246200:SPO_RS08425
uniprot id: Q5LSV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS04715
gene id: 246200:SPO_RS04715
uniprot id: Q5LUW3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

246200:SPO RS19485
gene id: 246200:SPO_RS19485
uniprot id: Q5LLT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

246200:SPO RS21025
gene id: 246200:SPO_RS21025
uniprot id: Q5LKZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

246200:SPO RS13045
gene id: 246200:SPO_RS13045
uniprot id: Q5LQC1
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

246200:SPO RS14735
gene id: 246200:SPO_RS14735
uniprot id: Q5LPE4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

246200:SPO RS21470
gene id: 246200:SPO_RS21470
uniprot id: Q5LKQ5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS20010
gene id: 246200:SPO_RS20010
uniprot id: F7IU51
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS07190
gene id: 246200:SPO_RS07190
uniprot id: Q5LTK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

246200:SPO RS10200
gene id: 246200:SPO_RS10200
uniprot id: Q5LRW1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS19100
gene id: 246200:SPO_RS19100
uniprot id: Q5LM00
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

246200:SPO RS04950
gene id: 246200:SPO_RS04950
uniprot id: Q5LUS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

246200:SPO RS12010
gene id: 246200:SPO_RS12010
uniprot id: Q5LQW6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

246200:SPO RS08115
gene id: 246200:SPO_RS08115
uniprot id: Q5LT19
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.

246200:SPO RS14340
gene id: 246200:SPO_RS14340
uniprot id: Q5LPM5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

246200:SPO RS07185
gene id: 246200:SPO_RS07185
uniprot id: Q5LTK6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

246200:SPO RS14905
gene id: 246200:SPO_RS14905
uniprot id: Q5LPA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

246200:SPO RS10175
gene id: 246200:SPO_RS10175
uniprot id: Q5LRW6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS11745
gene id: 246200:SPO_RS11745
uniprot id: Q5LR15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
messages: Cell membrane
messages: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (CcmA) and two transmembrane proteins (CcmB).

246200:SPO RS10075
gene id: 246200:SPO_RS10075
uniprot id: Q5LRY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

246200:SPO RS11515
gene id: 246200:SPO_RS11515
uniprot id: Q5LR60
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

246200:SPO RS16810
gene id: 246200:SPO_RS16810
uniprot id: Q5LN93
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS21415
gene id: 246200:SPO_RS21415
uniprot id: Q5LKR6
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

246200:SPO RS13630
gene id: 246200:SPO_RS13630
uniprot id: Q5LQ09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

246200:SPO RS14080
gene id: 246200:SPO_RS14080
uniprot id: Q5LPS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

246200:SPO RS04065
gene id: 246200:SPO_RS04065
uniprot id: Q5LV96
names: Similarity
messages: Belongs to the TrpF family.

246200:SPO RS10595
gene id: 246200:SPO_RS10595
uniprot id: Q5LRN6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

246200:SPO RS07980
gene id: 246200:SPO_RS07980
uniprot id: Q5LT46
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

246200:SPO RS09575
gene id: 246200:SPO_RS09575
uniprot id: Q5LS84
names: Cofactor
messages: Binds 1 zinc ion per subunit.

246200:SPO RS14305
gene id: 246200:SPO_RS14305
uniprot id: Q5LPN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

246200:SPO RS14760
gene id: 246200:SPO_RS14760
uniprot id: Q5LPD9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Multidrug efflux pump.

246200:SPO RS20160
gene id: 246200:SPO_RS20160
uniprot id: Q5LLF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

246200:SPO RS01020
gene id: 246200:SPO_RS01020
uniprot id: Q5LWY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

246200:SPO RS01515
gene id: 246200:SPO_RS01515
uniprot id: Q5LX82
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

246200:SPO RS17590
gene id: 246200:SPO_RS17590
uniprot id: Q5LMT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

246200:SPO RS02445
gene id: 246200:SPO_RS02445
uniprot id: Q5LW58
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

246200:SPO RS04755
gene id: 246200:SPO_RS04755
uniprot id: Q5LUV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

246200:SPO RS20750
gene id: 246200:SPO_RS20750
uniprot id: Q5LL46
names: Similarity
messages: Belongs to the SCO1/2 family.

246200:SPO RS07595
gene id: 246200:SPO_RS07595
uniprot id: Q5LTC3
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS15810
gene id: 246200:SPO_RS15810
uniprot id: Q5LNT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

246200:SPO RS05495
gene id: 246200:SPO_RS05495
uniprot id: Q5LUH1
names: Similarity
messages: Belongs to the sulfatase family.

246200:SPO RS07965
gene id: 246200:SPO_RS07965
uniprot id: Q5LT49
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

246200:SPO RS08730
gene id: 246200:SPO_RS08730
uniprot id: Q5LSQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

246200:SPO RS08545
gene id: 246200:SPO_RS08545
uniprot id: Q5LST2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

246200:SPO RS05440
gene id: 246200:SPO_RS05440
uniprot id: Q5LUI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

246200:SPO RS18085
gene id: 246200:SPO_RS18085
uniprot id: Q5LMJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

246200:SPO RS03080
gene id: 246200:SPO_RS03080
uniprot id: Q5LVT5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

246200:SPO RS14895
gene id: 246200:SPO_RS14895
uniprot id: Q5LPB1
names: Similarity
messages: Belongs to the SCO1/2 family.

246200:SPO RS16745
gene id: 246200:SPO_RS16745
uniprot id: Q5LNA5
names: Subunit
messages: Monomer.

246200:SPO RS00750
gene id: 246200:SPO_RS00750
uniprot id: Q5LWT9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

246200:SPO RS11355
gene id: 246200:SPO_RS11355
uniprot id: Q5LR89
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

246200:SPO RS11955
gene id: 246200:SPO_RS11955
uniprot id: Q5LQX6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

246200:SPO RS11360
gene id: 246200:SPO_RS11360
uniprot id: Q5LR88
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

246200:SPO RS08355
gene id: 246200:SPO_RS08355
uniprot id: Q5LSX1
names: Similarity
messages: Belongs to the selenium-binding protein family.

246200:SPO RS00220
gene id: 246200:SPO_RS00220
uniprot id: Q5LWJ5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

246200:SPO RS19635
gene id: 246200:SPO_RS19635
uniprot id: Q5LLQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

246200:SPO RS16630
gene id: 246200:SPO_RS16630
uniprot id: Q5LNC8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

246200:SPO RS00535
gene id: 246200:SPO_RS00535
uniprot id: Q5LWQ9
names: Similarity
messages: Belongs to the UPF0246 family.

246200:SPO RS02280
gene id: 246200:SPO_RS02280
uniprot id: Q5LW91
names: Similarity
messages: Belongs to the peptidase S13 family.

246200:SPO RS06745
gene id: 246200:SPO_RS06745
uniprot id: Q5LTT9
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

246200:SPO RS02225
gene id: 246200:SPO_RS02225
uniprot id: Q5LWA2
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

246200:SPO RS11860
gene id: 246200:SPO_RS11860
uniprot id: Q5LQZ2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

246200:SPO RS10425
gene id: 246200:SPO_RS10425
uniprot id: Q5LRS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

246200:SPO RS02715
gene id: 246200:SPO_RS02715
uniprot id: Q5LW05
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

246200:SPO RS10910
gene id: 246200:SPO_RS10910
uniprot id: Q5LRH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

246200:SPO RS13605
gene id: 246200:SPO_RS13605
uniprot id: Q5LQ14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

246200:SPO RS19255
gene id: 246200:SPO_RS19255
uniprot id: Q5LLX0
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

246200:SPO RS11685
gene id: 246200:SPO_RS11685
uniprot id: Q5LR27
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

246200:SPO RS00520
gene id: 246200:SPO_RS00520
uniprot id: Q5LWR2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

246200:SPO RS17120
gene id: 246200:SPO_RS17120
uniprot id: Q5LN32
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

246200:SPO RS04965
gene id: 246200:SPO_RS04965
uniprot id: Q5LUR7
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

246200:SPO RS20825
gene id: 246200:SPO_RS20825
uniprot id: Q5LL31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

246200:SPO RS04020
gene id: 246200:SPO_RS04020
uniprot id: Q5LVA5
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS03540
gene id: 246200:SPO_RS03540
uniprot id: Q5LVK0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

246200:SPO RS19810
gene id: 246200:SPO_RS19810
uniprot id: Q5LLK3
names: Similarity
messages: Belongs to the PhoH family.

246200:SPO RS17905
gene id: 246200:SPO_RS17905
uniprot id: Q5LMM9
names: Subcellular Location Annotation
messages: Cell inner membrane

246200:SPO RS20830
gene id: 246200:SPO_RS20830
uniprot id: Q5LL30
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS07920
gene id: 246200:SPO_RS07920
uniprot id: Q5LT58
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

246200:SPO RS14970
gene id: 246200:SPO_RS14970
uniprot id: Q5LP96
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS14530
gene id: 246200:SPO_RS14530
uniprot id: Q5LPI6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

246200:SPO RS21000
gene id: 246200:SPO_RS21000
uniprot id: Q5LKZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS04895
gene id: 246200:SPO_RS04895
uniprot id: Q5LUS9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

246200:SPO RS00820
gene id: 246200:SPO_RS00820
uniprot id: Q5LWW1
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

246200:SPO RS02575
gene id: 246200:SPO_RS02575
uniprot id: Q5LW33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

246200:SPO RS20525
gene id: 246200:SPO_RS20525
uniprot id: Q5LL90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

246200:SPO RS09900
gene id: 246200:SPO_RS09900
uniprot id: Q5LS20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

246200:SPO RS09800
gene id: 246200:SPO_RS09800
uniprot id: Q5LS40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

246200:SPO RS14455
gene id: 246200:SPO_RS14455
uniprot id: Q5LPK1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

246200:SPO RS21160
gene id: 246200:SPO_RS21160
uniprot id: Q5LKW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

246200:SPO RS06810
gene id: 246200:SPO_RS06810
uniprot id: Q5LTS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

246200:SPO RS15795
gene id: 246200:SPO_RS15795
uniprot id: Q5LNT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

246200:SPO RS15270
gene id: 246200:SPO_RS15270
uniprot id: Q5LP40
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

246200:SPO RS12515
gene id: 246200:SPO_RS12515
uniprot id: Q5LQM4
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

246200:SPO RS20630
gene id: 246200:SPO_RS20630
uniprot id: Q5LL69
names: Function
names: Induction
names: Similarity
names: Subunit
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
messages: Catalyzes the desulfonation and deamination of L-cysteate, yielding pyruvate, sulphite and ammonium. Is involved in a L-cysteate degradation pathway that allows Silicibacter pomeroyi to grow on L-cysteate as the sole source of carbon and energy. To a lesser extent, can also act on D-cysteine in vitro, leading to the production of pyruvate, sulfide and ammonium. L-cysteine, L-cysteine sulfinate, and 1-aminocyclopropane-1-carboxylate (ACC) are not substrates for the enzyme.
messages: Expressed in cells grown on L-cysteate, but not on acetate or taurine. Cotranscribed with cuyZ, with which it is likely to form an operon.
messages: Homomultimer, maybe a homotrimer.

246200:SPO RS00090
gene id: 246200:SPO_RS00090
uniprot id: Q5LWG3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

246200:SPO RS18370
gene id: 246200:SPO_RS18370
uniprot id: Q5LMD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).
messages: Homodimer or monomer when oxidized or reduced, respectively.
messages: chloroplast

246200:SPO RS08535
gene id: 246200:SPO_RS08535
uniprot id: Q5LST5
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

246200:SPO RS08440
gene id: 246200:SPO_RS08440
uniprot id: Q5LSV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

246200:SPO RS00060
gene id: 246200:SPO_RS00060
uniprot id: Q5LWG9
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

246200:SPO RS16990
gene id: 246200:SPO_RS16990
uniprot id: Q5LN58
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

246200:SPO RS16975
gene id: 246200:SPO_RS16975
uniprot id: Q5LN61
names: Similarity
messages: Belongs to the AHA1 family.

246200:SPO RS20305
gene id: 246200:SPO_RS20305
uniprot id: Q5LLD0
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS08795
gene id: 246200:SPO_RS08795
uniprot id: Q5LSN7
names: Similarity
messages: Belongs to the peptidase S33 family.

246200:SPO RS11220
gene id: 246200:SPO_RS11220
uniprot id: Q5LRB6
names: Similarity
messages: Belongs to the HIBADH-related family.

246200:SPO RS07765
gene id: 246200:SPO_RS07765
uniprot id: Q5LT88
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

246200:SPO RS12405
gene id: 246200:SPO_RS12405
uniprot id: Q5LQP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS14290
gene id: 246200:SPO_RS14290
uniprot id: Q5LPN5
names: Subcellular Location Annotation
messages: Cell inner membrane

246200:SPO RS20815
gene id: 246200:SPO_RS20815
uniprot id: Q5LL33
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

246200:SPO RS16475
gene id: 246200:SPO_RS16475
uniprot id: Q5LNF2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

246200:SPO RS21395
gene id: 246200:SPO_RS21395
uniprot id: Q5LKR9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS22180
gene id: 246200:SPO_RS22180
uniprot id: Q5LT15
names: Similarity
messages: Belongs to the PrpD family.

246200:SPO RS17895
gene id: 246200:SPO_RS17895
uniprot id: Q5LMN1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

246200:SPO RS20490
gene id: 246200:SPO_RS20490
uniprot id: Q5LL95
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

246200:SPO RS18880
gene id: 246200:SPO_RS18880
uniprot id: Q5LM44
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

246200:SPO RS03230
gene id: 246200:SPO_RS03230
uniprot id: Q5LVR1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS00960
gene id: 246200:SPO_RS00960
uniprot id: Q5LWY2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

246200:SPO RS14185
gene id: 246200:SPO_RS14185
uniprot id: Q5LPQ6
names: Similarity
messages: Belongs to the OmpW/AlkL family.

246200:SPO RS02390
gene id: 246200:SPO_RS02390
uniprot id: Q5LW68
names: Function
names: Similarity
messages: Belongs to the ribose 1,5-bisphosphokinase family.
messages: Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).

246200:SPO RS15050
gene id: 246200:SPO_RS15050
uniprot id: Q5LP80
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

246200:SPO RS05745
gene id: 246200:SPO_RS05745
uniprot id: Q5LUC2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

246200:SPO RS18545
gene id: 246200:SPO_RS18545
uniprot id: Q5LMA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

246200:SPO RS00230
gene id: 246200:SPO_RS00230
uniprot id: Q5LWJ3
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

246200:SPO RS00855
gene id: 246200:SPO_RS00855
uniprot id: Q5LWW8
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

246200:SPO RS02155
gene id: 246200:SPO_RS02155
uniprot id: Q5LWB6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

246200:SPO RS04470
gene id: 246200:SPO_RS04470
uniprot id: Q5LV15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

246200:SPO RS04435
gene id: 246200:SPO_RS04435
uniprot id: Q5LV23
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

246200:SPO RS16280
gene id: 246200:SPO_RS16280
uniprot id: Q5LNJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

246200:SPO RS02935
gene id: 246200:SPO_RS02935
uniprot id: Q5LVW3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

246200:SPO RS14520
gene id: 246200:SPO_RS14520
uniprot id: Q5LPI8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS05585
gene id: 246200:SPO_RS05585
uniprot id: Q5LUF3
names: Cofactor
names: Domain
names: Function
names: PTM
names: Subunit
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Consists of an N-terminal biotin carboxylation/carboxylase (BC) domain that catalyzes the transient carboxylation of the biotin covalently attached to the C-terminal biotinyl-binding/biotin carboxyl carrier (BCC) domain.
messages: The biotin cofactor is covalently attached to the C-terminal biotinyl-binding domain and is required for the catalytic activity.
messages: The holoenzyme is a dodecamer composed of 6 PccA/alpha subunits and 6 PccB/beta subunits.
messages: This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), the enzyme catalyzing the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl-CoA/(S)-methylmalonyl-CoA (PubMed:20725044). Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, while the beta subunit then tranfers the carboxyl group from carboxylated biotin to propionyl-CoA (Probable).

246200:SPO RS02625
gene id: 246200:SPO_RS02625
uniprot id: Q5LW23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

246200:SPO RS17850
gene id: 246200:SPO_RS17850
uniprot id: Q5LMP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.
messages: Membrane

246200:SPO RS12485
gene id: 246200:SPO_RS12485
uniprot id: Q5LQN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

246200:SPO RS06135
gene id: 246200:SPO_RS06135
uniprot id: Q5LU49
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M81 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC).

246200:SPO RS10690
gene id: 246200:SPO_RS10690
uniprot id: Q5LRL7
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

246200:SPO RS09285
gene id: 246200:SPO_RS09285
uniprot id: Q5LSE3
names: Function
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

246200:SPO RS00035
gene id: 246200:SPO_RS00035
uniprot id: Q5LWF7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

246200:SPO RS08575
gene id: 246200:SPO_RS08575
uniprot id: Q5LSS6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS19855
gene id: 246200:SPO_RS19855
uniprot id: Q5LLK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

246200:SPO RS10925
gene id: 246200:SPO_RS10925
uniprot id: Q5LRH3
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS19300
gene id: 246200:SPO_RS19300
uniprot id: Q5LLW7
names: Disruption Phenotype
names: Function
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Cells lacking this gene do not grow on methylmercaptopropionate (MMPA) as the sole source of carbon.
messages: Involved in the assimilation of dimethylsulphoniopropionate (DMSP), an important compound in the fixation of carbon in marine phytoplankton, by mediating the conversion of 3-(methylthio)propanoyl-CoA (MMPA-CoA) to 3-(methylthio)acryloyl-CoA (MTA-CoA).

246200:SPO RS02850
gene id: 246200:SPO_RS02850
uniprot id: Q5LVY0
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

246200:SPO RS02070
gene id: 246200:SPO_RS02070
uniprot id: Q5LWD3
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

246200:SPO RS07770
gene id: 246200:SPO_RS07770
uniprot id: Q5LT87
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS16055
gene id: 246200:SPO_RS16055
uniprot id: Q5LNN4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

246200:SPO RS18280
gene id: 246200:SPO_RS18280
uniprot id: Q5LMF5
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

246200:SPO RS21595
gene id: 246200:SPO_RS21595
uniprot id: Q5LKN4
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS13320
gene id: 246200:SPO_RS13320
uniprot id: Q5LQ70
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

246200:SPO RS03215
gene id: 246200:SPO_RS03215
uniprot id: Q5LVR5
names: Similarity
messages: Belongs to the GcvT family.

246200:SPO RS00350
gene id: 246200:SPO_RS00350
uniprot id: Q5LWM4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

246200:SPO RS04055
gene id: 246200:SPO_RS04055
uniprot id: Q5LV98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

246200:SPO RS11735
gene id: 246200:SPO_RS11735
uniprot id: Q5LR17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

246200:SPO RS08955
gene id: 246200:SPO_RS08955
uniprot id: Q5LSK6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

246200:SPO RS04155
gene id: 246200:SPO_RS04155
uniprot id: Q5LV78
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS19915
gene id: 246200:SPO_RS19915
uniprot id: Q5LLJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

246200:SPO RS21890
gene id: 246200:SPO_RS21890
uniprot id: Q5LKH5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

246200:SPO RS19695
gene id: 246200:SPO_RS19695
uniprot id: Q5LLP2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

246200:SPO RS04385
gene id: 246200:SPO_RS04385
uniprot id: Q5LV32
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS21080
gene id: 246200:SPO_RS21080
uniprot id: Q5LKY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

246200:SPO RS17705
gene id: 246200:SPO_RS17705
uniprot id: Q5LMR6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

246200:SPO RS21215
gene id: 246200:SPO_RS21215
uniprot id: Q5LKV4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

246200:SPO RS20660
gene id: 246200:SPO_RS20660
uniprot id: Q5LL63
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS05820
gene id: 246200:SPO_RS05820
uniprot id: Q5LUA7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Monomer (PubMed:19362561). The complex comprises the extracytoplasmic solute receptor protein UehA, and the two transmembrane proteins UehB and UehC (Probable).
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system UehABC, which imports both ectoine and 5-hydroxyectoine as nutrients, and not as osmoprotectants. UehA binds both ectoine and 5-hydroxyectoine with high specificity and affinity.
messages: Periplasm
messages: Transport is enhanced in cells that are grown in the presence of ectoine, but not by high-salinity media.

246200:SPO RS08180
gene id: 246200:SPO_RS08180
uniprot id: Q5LT06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS09600
gene id: 246200:SPO_RS09600
uniprot id: Q5LS79
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

246200:SPO RS16295
gene id: 246200:SPO_RS16295
uniprot id: Q5LNI7
names: Caution
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

246200:SPO RS02500
gene id: 246200:SPO_RS02500
uniprot id: Q5LW48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

246200:SPO RS13085
gene id: 246200:SPO_RS13085
uniprot id: Q5LQB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

246200:SPO RS12595
gene id: 246200:SPO_RS12595
uniprot id: Q5LQK9
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

246200:SPO RS21950
gene id: 246200:SPO_RS21950
uniprot id: Q5LKG2
names: Similarity
messages: Belongs to the PhzF family.

246200:SPO RS12720
gene id: 246200:SPO_RS12720
uniprot id: Q5LQI4
names: Similarity
messages: Belongs to the HesB/IscA family.

246200:SPO RS07685
gene id: 246200:SPO_RS07685
uniprot id: Q5LTA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

246200:SPO RS06695
gene id: 246200:SPO_RS06695
uniprot id: Q5LTU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

246200:SPO RS07620
gene id: 246200:SPO_RS07620
uniprot id: Q5LTB8
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS11575
gene id: 246200:SPO_RS11575
uniprot id: Q5LR48
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

246200:SPO RS01050
gene id: 246200:SPO_RS01050
uniprot id: Q5LWZ8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS20740
gene id: 246200:SPO_RS20740
uniprot id: Q5LL48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

246200:SPO RS04535
gene id: 246200:SPO_RS04535
uniprot id: Q5LV02
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

246200:SPO RS10380
gene id: 246200:SPO_RS10380
uniprot id: Q5LRS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

246200:SPO RS01655
gene id: 246200:SPO_RS01655
uniprot id: Q5LXA9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

246200:SPO RS17050
gene id: 246200:SPO_RS17050
uniprot id: Q5LN46
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

246200:SPO RS19920
gene id: 246200:SPO_RS19920
uniprot id: Q5LLJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

246200:SPO RS02520
gene id: 246200:SPO_RS02520
uniprot id: Q5LW44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

246200:SPO RS17410
gene id: 246200:SPO_RS17410
uniprot id: Q5LMX3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

246200:SPO RS12480
gene id: 246200:SPO_RS12480
uniprot id: Q5LQN1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

246200:SPO RS02440
gene id: 246200:SPO_RS02440
uniprot id: Q5LW59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

246200:SPO RS06870
gene id: 246200:SPO_RS06870
uniprot id: Q5LTR5
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

246200:SPO RS05705
gene id: 246200:SPO_RS05705
uniprot id: Q5LUD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

246200:SPO RS19835
gene id: 246200:SPO_RS19835
uniprot id: Q5LLL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

246200:SPO RS17135
gene id: 246200:SPO_RS17135
uniprot id: Q5LN29
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

246200:SPO RS08885
gene id: 246200:SPO_RS08885
uniprot id: Q5LSM1
names: Similarity
messages: Belongs to the GcvT family.

246200:SPO RS11765
gene id: 246200:SPO_RS11765
uniprot id: Q5LR11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

246200:SPO RS20570
gene id: 246200:SPO_RS20570
uniprot id: Q5LL81
names: Similarity
messages: Belongs to the DSD1 family.

246200:SPO RS14040
gene id: 246200:SPO_RS14040
uniprot id: Q5LPT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

246200:SPO RS19450
gene id: 246200:SPO_RS19450
uniprot id: Q5LLT8
names: Similarity
messages: Belongs to the DEAD box helicase family.

246200:SPO RS20065
gene id: 246200:SPO_RS20065
uniprot id: Q5LLG9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

246200:SPO RS16205
gene id: 246200:SPO_RS16205
uniprot id: Q5LNK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

246200:SPO RS11850
gene id: 246200:SPO_RS11850
uniprot id: Q5LQZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

246200:SPO RS17915
gene id: 246200:SPO_RS17915
uniprot id: Q5LMM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS04605
gene id: 246200:SPO_RS04605
uniprot id: Q5LUY8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

246200:SPO RS01775
gene id: 246200:SPO_RS01775
uniprot id: Q5LXE1
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

246200:SPO RS15595
gene id: 246200:SPO_RS15595
uniprot id: Q5LNX5
names: Similarity
messages: Belongs to the DprA/Smf family.

246200:SPO RS05735
gene id: 246200:SPO_RS05735
uniprot id: Q5LUC4
names: Similarity
messages: Belongs to the thioesterase PaaI family.

246200:SPO RS03620
gene id: 246200:SPO_RS03620
uniprot id: Q5LVI4
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

246200:SPO RS09220
gene id: 246200:SPO_RS09220
uniprot id: Q5LSF6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

246200:SPO RS01555
gene id: 246200:SPO_RS01555
uniprot id: Q5LX93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

246200:SPO RS17035
gene id: 246200:SPO_RS17035
uniprot id: Q5LN49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

246200:SPO RS01120
gene id: 246200:SPO_RS01120
uniprot id: Q5LX20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

246200:SPO RS04915
gene id: 246200:SPO_RS04915
uniprot id: Q5LUS5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

246200:SPO RS14395
gene id: 246200:SPO_RS14395
uniprot id: Q5LPL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

246200:SPO RS00895
gene id: 246200:SPO_RS00895
uniprot id: Q5LWX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

246200:SPO RS04095
gene id: 246200:SPO_RS04095
uniprot id: Q5LV90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

246200:SPO RS17730
gene id: 246200:SPO_RS17730
uniprot id: Q5LMR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

246200:SPO RS20040
gene id: 246200:SPO_RS20040
uniprot id: Q5LLH4
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS09280
gene id: 246200:SPO_RS09280
uniprot id: Q5LSE4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS16095
gene id: 246200:SPO_RS16095
uniprot id: Q5LNM6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

246200:SPO RS19005
gene id: 246200:SPO_RS19005
uniprot id: Q5LM19
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

246200:SPO RS01385
gene id: 246200:SPO_RS01385
uniprot id: Q5LX55
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Cell membrane
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

246200:SPO RS03580
gene id: 246200:SPO_RS03580
uniprot id: Q5LVJ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

246200:SPO RS09715
gene id: 246200:SPO_RS09715
uniprot id: Q5LS56
names: Disruption Phenotype
names: Function
names: Induction
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 25-fold increased sensitivity to acrylate, growth is strongly inhibited by 20 mM dimethylsulfonioproprionate (DMSP).
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Acrylyl-CoA reductase subfamily.
messages: By dimethylsulfonioproprionate (DMSP) and acrylate.
messages: Cytoplasm
messages: Homodimer.
messages: Probably catalyzes the NADPH-dependent reduction of acrylyl-CoA to propanoyl-CoA. Restores acrylate resistance when expressed in an E.coli strain K12 acuI deletion.
messages: The zinc-binding residues of the alcohol dehydrogenase family are not conserved.

246200:SPO RS17060
gene id: 246200:SPO_RS17060
uniprot id: Q5LN44
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

246200:SPO RS09410
gene id: 246200:SPO_RS09410
uniprot id: Q5LSB8
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS19215
gene id: 246200:SPO_RS19215
uniprot id: Q5LLX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS21005
gene id: 246200:SPO_RS21005
uniprot id: Q5LKZ5
names: Similarity
messages: Belongs to the arginase family.

246200:SPO RS06315
gene id: 246200:SPO_RS06315
uniprot id: Q5LU19
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

246200:SPO RS19735
gene id: 246200:SPO_RS19735
uniprot id: Q5LLN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

246200:SPO RS12950
gene id: 246200:SPO_RS12950
uniprot id: Q5LQD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

246200:SPO RS19435
gene id: 246200:SPO_RS19435
uniprot id: Q5LLU1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

246200:SPO RS11210
gene id: 246200:SPO_RS11210
uniprot id: Q5LRB8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

246200:SPO RS11545
gene id: 246200:SPO_RS11545
uniprot id: Q5LR54
names: Subcellular Location Annotation
messages: Cell membrane

246200:SPO RS11060
gene id: 246200:SPO_RS11060
uniprot id: Q5LRE8
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS17555
gene id: 246200:SPO_RS17555
uniprot id: Q5LMU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS11845
gene id: 246200:SPO_RS11845
uniprot id: Q5LQZ5
names: Similarity
messages: Belongs to the LOG family.

246200:SPO RS21535
gene id: 246200:SPO_RS21535
uniprot id: Q5LKP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

246200:SPO RS22070
gene id: 246200:SPO_RS22070
uniprot id: Q5LKD7
names: Similarity
messages: Belongs to the thioester dehydratase family. FabA subfamily.

246200:SPO RS21120
gene id: 246200:SPO_RS21120
uniprot id: Q5LKX2
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS14545
gene id: 246200:SPO_RS14545
uniprot id: Q5LPI3
names: Similarity
messages: Belongs to the CobH/CbiC family.

246200:SPO RS13395
gene id: 246200:SPO_RS13395
uniprot id: Q5LQ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

246200:SPO RS09990
gene id: 246200:SPO_RS09990
uniprot id: Q5LS02
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

246200:SPO RS09245
gene id: 246200:SPO_RS09245
uniprot id: Q5LSF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

246200:SPO RS09350
gene id: 246200:SPO_RS09350
uniprot id: Q5LSD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS13985
gene id: 246200:SPO_RS13985
uniprot id: Q5LPU6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

246200:SPO RS21390
gene id: 246200:SPO_RS21390
uniprot id: Q5LKS0
names: Similarity
messages: Belongs to the GcvT family.

246200:SPO RS14720
gene id: 246200:SPO_RS14720
uniprot id: Q5LPE7
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

246200:SPO RS06645
gene id: 246200:SPO_RS06645
uniprot id: Q5LTV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

246200:SPO RS18230
gene id: 246200:SPO_RS18230
uniprot id: Q5LMG4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

246200:SPO RS10990
gene id: 246200:SPO_RS10990
uniprot id: Q5LRG0
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

246200:SPO RS12655
gene id: 246200:SPO_RS12655
uniprot id: Q5LQJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

246200:SPO RS15120
gene id: 246200:SPO_RS15120
uniprot id: Q5LP67
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

246200:SPO RS05650
gene id: 246200:SPO_RS05650
uniprot id: Q5LUE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS00100
gene id: 246200:SPO_RS00100
uniprot id: Q5LWG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

246200:SPO RS01290
gene id: 246200:SPO_RS01290
uniprot id: Q5LX36
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS07290
gene id: 246200:SPO_RS07290
uniprot id: Q5LTI4
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS11530
gene id: 246200:SPO_RS11530
uniprot id: Q5LR57
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

246200:SPO RS03860
gene id: 246200:SPO_RS03860
uniprot id: Q5LVD7
names: Similarity
messages: Belongs to the glutamine synthetase family.

246200:SPO RS04395
gene id: 246200:SPO_RS04395
uniprot id: Q5LV30
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

246200:SPO RS12945
gene id: 246200:SPO_RS12945
uniprot id: Q5LQD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS04375
gene id: 246200:SPO_RS04375
uniprot id: Q5LV34
names: Subcellular Location Annotation
messages: Cell outer membrane

246200:SPO RS17910
gene id: 246200:SPO_RS17910
uniprot id: Q5LMM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

246200:SPO RS00135
gene id: 246200:SPO_RS00135
uniprot id: Q5LWH4
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS19995
gene id: 246200:SPO_RS19995
uniprot id: F7IWM1
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

246200:SPO RS04665
gene id: 246200:SPO_RS04665
uniprot id: Q5LUX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

246200:SPO RS18830
gene id: 246200:SPO_RS18830
uniprot id: Q5LM52
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

246200:SPO RS12065
gene id: 246200:SPO_RS12065
uniprot id: Q5LQV6
names: Similarity
messages: Belongs to the selenium-binding protein family.

246200:SPO RS20820
gene id: 246200:SPO_RS20820
uniprot id: Q5LL32
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

246200:SPO RS21775
gene id: 246200:SPO_RS21775
uniprot id: Q5LKJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS19770
gene id: 246200:SPO_RS19770
uniprot id: Q5LLM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

246200:SPO RS20060
gene id: 246200:SPO_RS20060
uniprot id: Q5LLH0
names: Similarity
messages: Belongs to the GcvT family.

246200:SPO RS10160
gene id: 246200:SPO_RS10160
uniprot id: Q5LRW9
names: Similarity
messages: Belongs to the histone deacetylase family.

246200:SPO RS17100
gene id: 246200:SPO_RS17100
uniprot id: Q5LN36
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

246200:SPO RS22175
gene id: 246200:SPO_RS22175
uniprot id: Q5LT18
names: Cofactor
names: Disruption Phenotype
names: Function
names: Similarity
names: Subunit
messages: Belongs to the non-heme iron-dependent dioxygenase family.
messages: Decreased dimethylsulfonioproprionate (DMSP) catabolism.
messages: Homodimer.
messages: May act as a dimethylsulfonioproprionate (DMSP) in vitro, releasing dimethyl sulfide (DMS). DMS is the principal form by which sulfur is transported from oceans to the atmosphere (PubMed:20880330). The real activity of the protein is however subject to debate and it is unclear whether it constitutes a real dimethylsulfonioproprionate lyase in vivo (Probable).
messages: Zn(2+) probably constitutes the cofactor in vivo.

246200:SPO RS00670
gene id: 246200:SPO_RS00670
uniprot id: Q5LWT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

246200:SPO RS15715
gene id: 246200:SPO_RS15715
uniprot id: Q5LNV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

246200:SPO RS09605
gene id: 246200:SPO_RS09605
uniprot id: Q5LS78
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

246200:SPO RS01075
gene id: 246200:SPO_RS01075
uniprot id: Q5LX11
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS00875
gene id: 246200:SPO_RS00875
uniprot id: Q3V7J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

246200:SPO RS13930
gene id: 246200:SPO_RS13930
uniprot id: Q5LPV7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

246200:SPO RS12460
gene id: 246200:SPO_RS12460
uniprot id: Q5LQN5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

246200:SPO RS08150
gene id: 246200:SPO_RS08150
uniprot id: Q5LT12
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

246200:SPO RS18855
gene id: 246200:SPO_RS18855
uniprot id: Q5LM49
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

246200:SPO RS08290
gene id: 246200:SPO_RS08290
uniprot id: Q5LSY4
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS00905
gene id: 246200:SPO_RS00905
uniprot id: Q5LWX5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

246200:SPO RS21265
gene id: 246200:SPO_RS21265
uniprot id: Q5LKU4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

246200:SPO RS21625
gene id: 246200:SPO_RS21625
uniprot id: Q5LKM7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS18530
gene id: 246200:SPO_RS18530
uniprot id: Q5LMA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

246200:SPO RS21880
gene id: 246200:SPO_RS21880
uniprot id: Q5LKH7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

246200:SPO RS09225
gene id: 246200:SPO_RS09225
uniprot id: Q5LSF5
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

246200:SPO RS14850
gene id: 246200:SPO_RS14850
uniprot id: Q5LPC0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

246200:SPO RS06000
gene id: 246200:SPO_RS06000
uniprot id: Q5LU74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

246200:SPO RS12565
gene id: 246200:SPO_RS12565
uniprot id: Q5LQL4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

246200:SPO RS02065
gene id: 246200:SPO_RS02065
uniprot id: Q5LWD4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

246200:SPO RS12740
gene id: 246200:SPO_RS12740
uniprot id: Q5LQI1
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

246200:SPO RS17735
gene id: 246200:SPO_RS17735
uniprot id: Q5LMR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

246200:SPO RS07255
gene id: 246200:SPO_RS07255
uniprot id: Q5LTJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

246200:SPO RS22055
gene id: 246200:SPO_RS22055
uniprot id: Q5LKE1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

246200:SPO RS19755
gene id: 246200:SPO_RS19755
uniprot id: Q5LLN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

246200:SPO RS11785
gene id: 246200:SPO_RS11785
uniprot id: Q5LR07
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

246200:SPO RS12315
gene id: 246200:SPO_RS12315
uniprot id: Q5LQR4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

246200:SPO RS00970
gene id: 246200:SPO_RS00970
uniprot id: Q5LWY0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

246200:SPO RS05055
gene id: 246200:SPO_RS05055
uniprot id: Q5LUP9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

246200:SPO RS10630
gene id: 246200:SPO_RS10630
uniprot id: Q5LRM9
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

246200:SPO RS02845
gene id: 246200:SPO_RS02845
uniprot id: Q5LVY1
names: Similarity
messages: Belongs to the GcvT family.

246200:SPO RS16730
gene id: 246200:SPO_RS16730
uniprot id: Q5LNA8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

246200:SPO RS21190
gene id: 246200:SPO_RS21190
uniprot id: Q5LKV8
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

246200:SPO RS02030
gene id: 246200:SPO_RS02030
uniprot id: Q5LWE1
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

246200:SPO RS14420
gene id: 246200:SPO_RS14420
uniprot id: Q5LPK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

246200:SPO RS15590
gene id: 246200:SPO_RS15590
uniprot id: Q5LNX6
names: Similarity
messages: Belongs to the peptidase U62 family.

246200:SPO RS03335
gene id: 246200:SPO_RS03335
uniprot id: Q5LVP0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

246200:SPO RS08690
gene id: 246200:SPO_RS08690
uniprot id: Q5LSQ8
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS03025
gene id: 246200:SPO_RS03025
uniprot id: Q5LVU6
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

246200:SPO RS04960
gene id: 246200:SPO_RS04960
uniprot id: Q5LUR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (ZnuC), two transmembrane proteins (ZnuB) and a solute-binding protein (ZnuA).

246200:SPO RS16910
gene id: 246200:SPO_RS16910
uniprot id: Q5LN74
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

246200:SPO RS18945
gene id: 246200:SPO_RS18945
uniprot id: Q5LM31
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

246200:SPO RS07275
gene id: 246200:SPO_RS07275
uniprot id: Q5LTI8
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

246200:SPO RS13665
gene id: 246200:SPO_RS13665
uniprot id: Q5LQ02
names: PTM
messages: Binds 1 heme group per subunit.

246200:SPO RS20785
gene id: 246200:SPO_RS20785
uniprot id: Q5LL39
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

246200:SPO RS01140
gene id: 246200:SPO_RS01140
uniprot id: Q5LX16
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Shows little dependence on metals.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert NDP to NTP. PolyP hydrolysis is slightly faster with GDP, but it can also use ADP, CDP and UDP.

246200:SPO RS12615
gene id: 246200:SPO_RS12615
uniprot id: Q5LQK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

246200:SPO RS19415
gene id: 246200:SPO_RS19415
uniprot id: Q5LLU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

246200:SPO RS03560
gene id: 246200:SPO_RS03560
uniprot id: Q5LVJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

246200:SPO RS05445
gene id: 246200:SPO_RS05445
uniprot id: Q5LUI1
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

246200:SPO RS18575
gene id: 246200:SPO_RS18575
uniprot id: Q5LM98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

246200:SPO RS20665
gene id: 246200:SPO_RS20665
uniprot id: Q5LL62
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS21820
gene id: 246200:SPO_RS21820
uniprot id: Q5LKI9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

246200:SPO RS10290
gene id: 246200:SPO_RS10290
uniprot id: Q5LRU6
names: Subunit
messages: Homodimer.

246200:SPO RS13160
gene id: 246200:SPO_RS13160
uniprot id: Q5LQ99
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

246200:SPO RS18160
gene id: 246200:SPO_RS18160
uniprot id: Q5LMH8
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

246200:SPO RS16785
gene id: 246200:SPO_RS16785
uniprot id: Q5LN97
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS04930
gene id: 246200:SPO_RS04930
uniprot id: Q5LUS2
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

246200:SPO RS17255
gene id: 246200:SPO_RS17255
uniprot id: Q5LN04
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

246200:SPO RS20995
gene id: 246200:SPO_RS20995
uniprot id: Q5LKZ7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

246200:SPO RS13115
gene id: 246200:SPO_RS13115
uniprot id: Q5LQA8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

246200:SPO RS14660
gene id: 246200:SPO_RS14660
uniprot id: Q5LPF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

246200:SPO RS14875
gene id: 246200:SPO_RS14875
uniprot id: Q5LPB5
names: Similarity
messages: Belongs to the Gfa family.

246200:SPO RS18985
gene id: 246200:SPO_RS18985
uniprot id: Q5LM23
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

246200:SPO RS15170
gene id: 246200:SPO_RS15170
uniprot id: Q5LP58
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

246200:SPO RS05935
gene id: 246200:SPO_RS05935
uniprot id: Q5LU87
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

246200:SPO RS06325
gene id: 246200:SPO_RS06325
uniprot id: Q5LU17
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

246200:SPO RS13500
gene id: 246200:SPO_RS13500
uniprot id: Q5LQ35
names: Similarity
messages: Belongs to the ABC transporter superfamily.

246200:SPO RS02205
gene id: 246200:SPO_RS02205
uniprot id: Q5LWA6
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

246200:SPO RS14300
gene id: 246200:SPO_RS14300
uniprot id: Q5LPN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

246200:SPO RS02290
gene id: 246200:SPO_RS02290
uniprot id: Q5LW89
names: Cofactor
names: Disruption Phenotype
names: Function
names: Induction
names: Similarity
names: Subunit
messages: Able to cleave dimethylsulfonioproprionate (DMSP), releasing dimethyl sulfide (DMS) and acrylate. DMS is the principal form by which sulfur is transported from oceans to the atmosphere.
messages: Belongs to the non-heme iron-dependent dioxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Decreased production of dimethyl sulfide (DMS).
messages: Homodimer.
messages: Up-regulated by pre-growth of cells with dimethylsulfonioproprionate (DMSP).

246200:SPO RS03345
gene id: 246200:SPO_RS03345
uniprot id: Q5LVN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

246200:SPO RS14630
gene id: 246200:SPO_RS14630
uniprot id: Q5LPG5
names: Similarity
messages: Belongs to the TPP enzyme family.

246200:SPO RS01965
gene id: 246200:SPO_RS01965
uniprot id: Q5LXH5
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS05160
gene id: 246200:SPO_RS05160
uniprot id: Q5LUM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

246200:SPO RS18240
gene id: 246200:SPO_RS18240
uniprot id: Q5LMG3
names: Similarity
messages: Belongs to the pyruvate kinase family.

246200:SPO RS19405
gene id: 246200:SPO_RS19405
uniprot id: Q5LLU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

246200:SPO RS07260
gene id: 246200:SPO_RS07260
uniprot id: Q5LTJ1
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

246200:SPO RS02900
gene id: 246200:SPO_RS02900
uniprot id: Q5LVX0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

246200:SPO RS15600
gene id: 246200:SPO_RS15600
uniprot id: Q5LNX4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

246200:SPO RS17025
gene id: 246200:SPO_RS17025
uniprot id: Q5LN51
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

246200:SPO RS20100
gene id: 246200:SPO_RS20100
uniprot id: Q5LLG2
names: Similarity
messages: Belongs to the TPP enzyme family.

246200:SPO RS17105
gene id: 246200:SPO_RS17105
uniprot id: Q5LN35
names: Similarity
messages: Belongs to the SDHAF4 family.

246200:SPO RS19745
gene id: 246200:SPO_RS19745
uniprot id: Q5LLN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

246200:SPO RS16425
gene id: 246200:SPO_RS16425
uniprot id: Q5LNG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

246200:SPO RS03490
gene id: 246200:SPO_RS03490
uniprot id: Q5LVK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

246200:SPO RS04805
gene id: 246200:SPO_RS04805
uniprot id: Q5LUU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

246200:SPO RS02605
gene id: 246200:SPO_RS02605
uniprot id: Q5LW27
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

246200:SPO RS17985
gene id: 246200:SPO_RS17985
uniprot id: Q5LML3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

246200:SPO RS19420
gene id: 246200:SPO_RS19420
uniprot id: Q5LLU4
names: Similarity
messages: Belongs to the UPF0178 family.

246200:SPO RS18330
gene id: 246200:SPO_RS18330
uniprot id: Q5LME5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS01700
gene id: 246200:SPO_RS01700
uniprot id: Q5LXB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

246200:SPO RS11725
gene id: 246200:SPO_RS11725
uniprot id: Q5LR18
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

246200:SPO RS21735
gene id: 246200:SPO_RS21735
uniprot id: Q5LKK6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS03950
gene id: 246200:SPO_RS03950
uniprot id: Q5LVB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS09270
gene id: 246200:SPO_RS09270
uniprot id: Q5LSE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS16780
gene id: 246200:SPO_RS16780
uniprot id: Q5LN98
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

246200:SPO RS06650
gene id: 246200:SPO_RS06650
uniprot id: Q5LTV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS15385
gene id: 246200:SPO_RS15385
uniprot id: Q5LP17
names: Similarity
messages: Belongs to the aspartokinase family.

246200:SPO RS16020
gene id: 246200:SPO_RS16020
uniprot id: Q5LNP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

246200:SPO RS04500
gene id: 246200:SPO_RS04500
uniprot id: Q5LV09
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

246200:SPO RS16880
gene id: 246200:SPO_RS16880
uniprot id: Q5LN80
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

246200:SPO RS03430
gene id: 246200:SPO_RS03430
uniprot id: Q5LVM1
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

246200:SPO RS06055
gene id: 246200:SPO_RS06055
uniprot id: Q5LU63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

246200:SPO RS21405
gene id: 246200:SPO_RS21405
uniprot id: Q5LKR7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS01465
gene id: 246200:SPO_RS01465
uniprot id: Q5LX74
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

246200:SPO RS00490
gene id: 246200:SPO_RS00490
uniprot id: Q5LWQ0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

246200:SPO RS11670
gene id: 246200:SPO_RS11670
uniprot id: Q5LR30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

246200:SPO RS12660
gene id: 246200:SPO_RS12660
uniprot id: Q5LQJ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

246200:SPO RS14870
gene id: 246200:SPO_RS14870
uniprot id: Q5LPB6
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

246200:SPO RS09505
gene id: 246200:SPO_RS09505
uniprot id: Q5LS98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

246200:SPO RS07460
gene id: 246200:SPO_RS07460
uniprot id: Q5LTF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS09070
gene id: 246200:SPO_RS09070
uniprot id: Q5LSI5
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

246200:SPO RS15980
gene id: 246200:SPO_RS15980
uniprot id: Q5LNP9
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

246200:SPO RS07865
gene id: 246200:SPO_RS07865
uniprot id: Q5LT69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

246200:SPO RS08870
gene id: 246200:SPO_RS08870
uniprot id: Q5LSM4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

246200:SPO RS11990
gene id: 246200:SPO_RS11990
uniprot id: Q5LQX0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

246200:SPO RS13600
gene id: 246200:SPO_RS13600
uniprot id: Q5LQ15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

246200:SPO RS03355
gene id: 246200:SPO_RS03355
uniprot id: Q5LVN6
names: Subcellular Location Annotation
messages: Cell inner membrane

246200:SPO RS09025
gene id: 246200:SPO_RS09025
uniprot id: Q5LSJ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Homodimer.

246200:SPO RS12500
gene id: 246200:SPO_RS12500
uniprot id: Q5LQM7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

246200:SPO RS14220
gene id: 246200:SPO_RS14220
uniprot id: Q5LPP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

246200:SPO RS16905
gene id: 246200:SPO_RS16905
uniprot id: Q5LN75
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

246200:SPO RS13635
gene id: 246200:SPO_RS13635
uniprot id: Q5LQ08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

246200:SPO RS02430
gene id: 246200:SPO_RS02430
uniprot id: Q5LW61
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

246200:SPO RS16500
gene id: 246200:SPO_RS16500
uniprot id: Q5LNE7
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

246200:SPO RS06705
gene id: 246200:SPO_RS06705
uniprot id: Q5LTU7
names: Function
names: Similarity
messages: Belongs to the nitrile hydratase subunit beta family.
messages: NHase catalyzes the hydration of various nitrile compounds to the corresponding amides.

246200:SPO RS12415
gene id: 246200:SPO_RS12415
uniprot id: Q5LQP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

246200:SPO RS16290
gene id: 246200:SPO_RS16290
uniprot id: Q5LNI8
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

246200:SPO RS10865
gene id: 246200:SPO_RS10865
uniprot id: Q5LRI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell inner membrane
messages: Homotetramer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

246200:SPO RS21030
gene id: 246200:SPO_RS21030
uniprot id: Q5LKZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS19185
gene id: 246200:SPO_RS19185
uniprot id: Q5LLY5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

246200:SPO RS19155
gene id: 246200:SPO_RS19155
uniprot id: Q5LLZ1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

246200:SPO RS03675
gene id: 246200:SPO_RS03675
uniprot id: Q5LMR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

246200:SPO RS03085
gene id: 246200:SPO_RS03085
uniprot id: Q5LVT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS07390
gene id: 246200:SPO_RS07390
uniprot id: Q5LTG4
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

246200:SPO RS03425
gene id: 246200:SPO_RS03425
uniprot id: Q5LVM2
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

246200:SPO RS17695
gene id: 246200:SPO_RS17695
uniprot id: Q5LMR8
names: Similarity
messages: Belongs to the GST superfamily.

246200:SPO RS01985
gene id: 246200:SPO_RS01985
uniprot id: Q5LWF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

246200:SPO RS15060
gene id: 246200:SPO_RS15060
uniprot id: Q5LP78
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS16385
gene id: 246200:SPO_RS16385
uniprot id: Q5LNH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

246200:SPO RS06450
gene id: 246200:SPO_RS06450
uniprot id: Q5LTZ4
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

246200:SPO RS07600
gene id: 246200:SPO_RS07600
uniprot id: Q5LTC2
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS21510
gene id: 246200:SPO_RS21510
uniprot id: Q5LKQ1
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

246200:SPO RS03565
gene id: 246200:SPO_RS03565
uniprot id: Q5LVJ5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

246200:SPO RS06765
gene id: 246200:SPO_RS06765
uniprot id: Q5LTT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

246200:SPO RS15565
gene id: 246200:SPO_RS15565
uniprot id: Q5LNY1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

246200:SPO RS17375
gene id: 246200:SPO_RS17375
uniprot id: Q5LMY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

246200:SPO RS19620
gene id: 246200:SPO_RS19620
uniprot id: Q5LLQ6
names: Similarity
messages: Belongs to the SCO1/2 family.

246200:SPO RS06905
gene id: 246200:SPO_RS06905
uniprot id: Q5LTQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

246200:SPO RS04100
gene id: 246200:SPO_RS04100
uniprot id: Q5LV89
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

246200:SPO RS11945
gene id: 246200:SPO_RS11945
uniprot id: Q5LQX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

246200:SPO RS08370
gene id: 246200:SPO_RS08370
uniprot id: Q5LSW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

246200:SPO RS08475
gene id: 246200:SPO_RS08475
uniprot id: Q5LSU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

246200:SPO RS06815
gene id: 246200:SPO_RS06815
uniprot id: Q5LTS5
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS03330
gene id: 246200:SPO_RS03330
uniprot id: Q5LVP1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS19565
gene id: 246200:SPO_RS19565
uniprot id: Q5LLR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

246200:SPO RS02555
gene id: 246200:SPO_RS02555
uniprot id: Q5LW37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

246200:SPO RS15985
gene id: 246200:SPO_RS15985
uniprot id: Q5LNP8
names: Similarity
messages: Belongs to the UPF0260 family.

246200:SPO RS02985
gene id: 246200:SPO_RS02985
uniprot id: Q5LVV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

246200:SPO RS10625
gene id: 246200:SPO_RS10625
uniprot id: Q5LRN0
names: Similarity
messages: Belongs to the PrpD family.

246200:SPO RS16330
gene id: 246200:SPO_RS16330
uniprot id: Q3V7J2
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

246200:SPO RS01585
gene id: 246200:SPO_RS01585
uniprot id: Q5LX88
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

246200:SPO RS10975
gene id: 246200:SPO_RS10975
uniprot id: Q5LRG3
names: Similarity
messages: Belongs to the SufE family.

246200:SPO RS09675
gene id: 246200:SPO_RS09675
uniprot id: Q5LS64
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

246200:SPO RS00525
gene id: 246200:SPO_RS00525
uniprot id: Q5LWR1
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

246200:SPO RS01975
gene id: 246200:SPO_RS01975
uniprot id: Q5LXH3
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

246200:SPO RS06035
gene id: 246200:SPO_RS06035
uniprot id: Q5LU67
names: Similarity
messages: Belongs to the GST superfamily.

246200:SPO RS01830
gene id: 246200:SPO_RS01830
uniprot id: Q5LXE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

246200:SPO RS18450
gene id: 246200:SPO_RS18450
uniprot id: Q5LMC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

246200:SPO RS21505
gene id: 246200:SPO_RS21505
uniprot id: Q5LKQ2
names: Caution
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

246200:SPO RS15615
gene id: 246200:SPO_RS15615
uniprot id: Q5LNX1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

246200:SPO RS08325
gene id: 246200:SPO_RS08325
uniprot id: Q5LSX7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

246200:SPO RS07645
gene id: 246200:SPO_RS07645
uniprot id: Q5LTB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PqqD family.
messages: Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
messages: Monomer. Interacts with PqqE.

246200:SPO RS19930
gene id: 246200:SPO_RS19930
uniprot id: Q5LLL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

246200:SPO RS15665
gene id: 246200:SPO_RS15665
uniprot id: Q5LNW2
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS19040
gene id: 246200:SPO_RS19040
uniprot id: Q5LM12
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.

246200:SPO RS15620
gene id: 246200:SPO_RS15620
uniprot id: Q5LNX0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

246200:SPO RS18570
gene id: 246200:SPO_RS18570
uniprot id: Q5LM99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS19940
gene id: 246200:SPO_RS19940
uniprot id: Q5LLL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

246200:SPO RS09520
gene id: 246200:SPO_RS09520
uniprot id: Q5LS95
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

246200:SPO RS06895
gene id: 246200:SPO_RS06895
uniprot id: Q5LTR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

246200:SPO RS17445
gene id: 246200:SPO_RS17445
uniprot id: Q5LMW6
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

246200:SPO RS12015
gene id: 246200:SPO_RS12015
uniprot id: Q5LQW5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

246200:SPO RS01730
gene id: 246200:SPO_RS01730
uniprot id: Q5LXD1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

246200:SPO RS05815
gene id: 246200:SPO_RS05815
uniprot id: Q5LUA8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system UehABC, which imports both ectoine and 5-hydroxyectoine as nutrients, and not as osmoprotectants.
messages: The complex comprises the extracytoplasmic solute receptor protein UehA, and the two transmembrane proteins UehB and UehC.
messages: Transport is enhanced in cells that are grown in the presence of ectoine, but not by high-salinity media.

246200:SPO RS11570
gene id: 246200:SPO_RS11570
uniprot id: Q5LR49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

246200:SPO RS13220
gene id: 246200:SPO_RS13220
uniprot id: Q5LQ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

246200:SPO RS01745
gene id: 246200:SPO_RS01745
uniprot id: Q5LXC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

246200:SPO RS17870
gene id: 246200:SPO_RS17870
uniprot id: Q5LMN6
names: Similarity
messages: Belongs to the universal stress protein A family.

246200:SPO RS09530
gene id: 246200:SPO_RS09530
uniprot id: Q5LS93
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

246200:SPO RS02585
gene id: 246200:SPO_RS02585
uniprot id: Q5LW31
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

246200:SPO RS12305
gene id: 246200:SPO_RS12305
uniprot id: Q5LQR6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

246200:SPO RS14910
gene id: 246200:SPO_RS14910
uniprot id: Q5LPA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

246200:SPO RS01110
gene id: 246200:SPO_RS01110
uniprot id: Q5LX04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

246200:SPO RS04200
gene id: 246200:SPO_RS04200
uniprot id: Q5LV69
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

246200:SPO RS18165
gene id: 246200:SPO_RS18165
uniprot id: Q5LMH7
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

246200:SPO RS07295
gene id: 246200:SPO_RS07295
uniprot id: Q5LTI3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

246200:SPO RS15160
gene id: 246200:SPO_RS15160
uniprot id: V5UZD8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

246200:SPO RS16300
gene id: 246200:SPO_RS16300
uniprot id: Q5LNI6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

246200:SPO RS10915
gene id: 246200:SPO_RS10915
uniprot id: Q5LRH5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

246200:SPO RS10235
gene id: 246200:SPO_RS10235
uniprot id: Q5LRV6
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

246200:SPO RS21690
gene id: 246200:SPO_RS21690
uniprot id: Q5LKL5
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS00650
gene id: 246200:SPO_RS00650
uniprot id: Q5LWS3
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

246200:SPO RS16865
gene id: 246200:SPO_RS16865
uniprot id: Q5LN83
names: Similarity
messages: Belongs to the globin family.

246200:SPO RS10190
gene id: 246200:SPO_RS10190
uniprot id: Q5LRW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS14205
gene id: 246200:SPO_RS14205
uniprot id: Q5LPQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

246200:SPO RS14045
gene id: 246200:SPO_RS14045
uniprot id: Q5LPT4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

246200:SPO RS10660
gene id: 246200:SPO_RS10660
uniprot id: Q5LRM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

246200:SPO RS17835
gene id: 246200:SPO_RS17835
uniprot id: Q5LMP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

246200:SPO RS20645
gene id: 246200:SPO_RS20645
uniprot id: Q5LL66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS15670
gene id: 246200:SPO_RS15670
uniprot id: Q5LNW1
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS17520
gene id: 246200:SPO_RS17520
uniprot id: Q5LMV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

246200:SPO RS17775
gene id: 246200:SPO_RS17775
uniprot id: Q5LMQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

246200:SPO RS10530
gene id: 246200:SPO_RS10530
uniprot id: Q5LRP9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

246200:SPO RS08315
gene id: 246200:SPO_RS08315
uniprot id: Q5LSX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

246200:SPO RS21015
gene id: 246200:SPO_RS21015
uniprot id: Q5LKZ3
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS10255
gene id: 246200:SPO_RS10255
uniprot id: Q5LRV2
names: Similarity
messages: Belongs to the UPF0145 family.

246200:SPO RS02865
gene id: 246200:SPO_RS02865
uniprot id: Q5LVX7
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

246200:SPO RS12710
gene id: 246200:SPO_RS12710
uniprot id: Q5LQI6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

246200:SPO RS00775
gene id: 246200:SPO_RS00775
uniprot id: Q5LWV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

246200:SPO RS18490
gene id: 246200:SPO_RS18490
uniprot id: Q5LMB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

246200:SPO RS16565
gene id: 246200:SPO_RS16565
uniprot id: Q5LNE0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

246200:SPO RS14980
gene id: 246200:SPO_RS14980
uniprot id: Q5LP94
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

246200:SPO RS00045
gene id: 246200:SPO_RS00045
uniprot id: Q5LWF5
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

246200:SPO RS21010
gene id: 246200:SPO_RS21010
uniprot id: Q5LKZ4
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

246200:SPO RS04920
gene id: 246200:SPO_RS04920
uniprot id: Q5LUS4
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

246200:SPO RS13035
gene id: 246200:SPO_RS13035
uniprot id: Q5LQC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

246200:SPO RS18565
gene id: 246200:SPO_RS18565
uniprot id: Q5LMA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS05950
gene id: 246200:SPO_RS05950
uniprot id: Q5LU84
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

246200:SPO RS07915
gene id: 246200:SPO_RS07915
uniprot id: Q5LT59
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

246200:SPO RS18745
gene id: 246200:SPO_RS18745
uniprot id: Q5LM69
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

246200:SPO RS09020
gene id: 246200:SPO_RS09020
uniprot id: Q5LSJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm
messages: Solute-binding protein that binds 3,4-dihydroxybenzoate and 3-hydroxybenzoate (in vitro) (PubMed:25540822). Probably part of a tripartite ATP-independent periplasmic (TRAP) transport system that mediates solute transport into the cytoplasm.
messages: The complex is comprised of an extracytoplasmic solute-binding protein and a heteromeric permease formed by two transmembrane proteins.

246200:SPO RS04700
gene id: 246200:SPO_RS04700
uniprot id: Q5LUW7
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

246200:SPO RS05080
gene id: 246200:SPO_RS05080
uniprot id: Q5LUP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

246200:SPO RS01820
gene id: 246200:SPO_RS01820
uniprot id: Q5LXF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

246200:SPO RS06770
gene id: 246200:SPO_RS06770
uniprot id: Q5LTT4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

246200:SPO RS09260
gene id: 246200:SPO_RS09260
uniprot id: Q5LSE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

246200:SPO RS19820
gene id: 246200:SPO_RS19820
uniprot id: Q5LLL4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

246200:SPO RS05085
gene id: 246200:SPO_RS05085
uniprot id: Q5LUP3
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

246200:SPO RS04390
gene id: 246200:SPO_RS04390
uniprot id: Q5LV31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

246200:SPO RS06780
gene id: 246200:SPO_RS06780
uniprot id: Q5LTT2
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

246200:SPO RS21210
gene id: 246200:SPO_RS21210
uniprot id: Q5LKV5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS18055
gene id: 246200:SPO_RS18055
uniprot id: Q5LMJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

246200:SPO RS05545
gene id: 246200:SPO_RS05545
uniprot id: Q5LUG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell inner membrane
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

246200:SPO RS13225
gene id: 246200:SPO_RS13225
uniprot id: Q5LQ88
names: Function
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

246200:SPO RS08905
gene id: 246200:SPO_RS08905
uniprot id: Q5LSL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

246200:SPO RS21550
gene id: 246200:SPO_RS21550
uniprot id: Q5LKP3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS08295
gene id: 246200:SPO_RS08295
uniprot id: Q5LSY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

246200:SPO RS15080
gene id: 246200:SPO_RS15080
uniprot id: Q5LP75
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS02655
gene id: 246200:SPO_RS02655
uniprot id: Q5LW17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

246200:SPO RS17350
gene id: 246200:SPO_RS17350
uniprot id: Q5LMY5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

246200:SPO RS16185
gene id: 246200:SPO_RS16185
uniprot id: Q5LNK8
names: Similarity
messages: Belongs to the histone deacetylase family.

246200:SPO RS21945
gene id: 246200:SPO_RS21945
uniprot id: Q5LKG3
names: Similarity
messages: Belongs to the TPP enzyme family.

246200:SPO RS16335
gene id: 246200:SPO_RS16335
uniprot id: Q5LNI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.

246200:SPO RS14120
gene id: 246200:SPO_RS14120
uniprot id: Q5LPR9
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

246200:SPO RS18365
gene id: 246200:SPO_RS18365
uniprot id: Q5LMD9
names: Subcellular Location Annotation
messages: Cytoplasm

246200:SPO RS05995
gene id: 246200:SPO_RS05995
uniprot id: Q5LU75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

246200:SPO RS11075
gene id: 246200:SPO_RS11075
uniprot id: Q5LRE5
names: Similarity
messages: Belongs to the universal stress protein A family.

246200:SPO RS03725
gene id: 246200:SPO_RS03725
uniprot id: Q5LVG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

246200:SPO RS21235
gene id: 246200:SPO_RS21235
uniprot id: Q5LKV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS19725
gene id: 246200:SPO_RS19725
uniprot id: Q5LLN6
names: Similarity
messages: Belongs to the Tim44 family.

246200:SPO RS00355
gene id: 246200:SPO_RS00355
uniprot id: Q5LWM3
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

246200:SPO RS16350
gene id: 246200:SPO_RS16350
uniprot id: Q5LNH7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

246200:SPO RS21795
gene id: 246200:SPO_RS21795
uniprot id: Q5LKJ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS04355
gene id: 246200:SPO_RS04355
uniprot id: Q5LV38
names: Similarity
messages: Belongs to the bacterial glucokinase family.

246200:SPO RS20550
gene id: 246200:SPO_RS20550
uniprot id: Q5LL85
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

246200:SPO RS18320
gene id: 246200:SPO_RS18320
uniprot id: Q5LME7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

246200:SPO RS19505
gene id: 246200:SPO_RS19505
uniprot id: Q5LLS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

246200:SPO RS03310
gene id: 246200:SPO_RS03310
uniprot id: Q5LVP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

246200:SPO RS15335
gene id: 246200:SPO_RS15335
uniprot id: Q5LP27
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

246200:SPO RS00325
gene id: 246200:SPO_RS00325
uniprot id: Q5LWL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

246200:SPO RS21300
gene id: 246200:SPO_RS21300
uniprot id: Q5LKT7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

246200:SPO RS01835
gene id: 246200:SPO_RS01835
uniprot id: Q5LXE7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

246200:SPO RS14035
gene id: 246200:SPO_RS14035
uniprot id: Q5LPT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

246200:SPO RS03400
gene id: 246200:SPO_RS03400
uniprot id: Q5LVM7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS07860
gene id: 246200:SPO_RS07860
uniprot id: Q5LT70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

246200:SPO RS20430
gene id: 246200:SPO_RS20430
uniprot id: Q5LLA6
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

246200:SPO RS00550
gene id: 246200:SPO_RS00550
uniprot id: Q5LWQ5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

246200:SPO RS13365
gene id: 246200:SPO_RS13365
uniprot id: Q5LQ61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

246200:SPO RS05805
gene id: 246200:SPO_RS05805
uniprot id: Q5LUB0
names: Similarity
messages: Belongs to the universal stress protein A family.

246200:SPO RS06440
gene id: 246200:SPO_RS06440
uniprot id: Q5LTZ6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS13570
gene id: 246200:SPO_RS13570
uniprot id: Q5LQ21
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS01570
gene id: 246200:SPO_RS01570
uniprot id: Q5LX91
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

246200:SPO RS00915
gene id: 246200:SPO_RS00915
uniprot id: Q3V7J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

246200:SPO RS11285
gene id: 246200:SPO_RS11285
uniprot id: Q5LRA4
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS00770
gene id: 246200:SPO_RS00770
uniprot id: Q5LWV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

246200:SPO RS17470
gene id: 246200:SPO_RS17470
uniprot id: Q5LMW1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

246200:SPO RS14855
gene id: 246200:SPO_RS14855
uniprot id: Q5LPB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

246200:SPO RS04225
gene id: 246200:SPO_RS04225
uniprot id: Q5LV64
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

246200:SPO RS00460
gene id: 246200:SPO_RS00460
uniprot id: Q5LWN8
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

246200:SPO RS00215
gene id: 246200:SPO_RS00215
uniprot id: Q5LWJ6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

246200:SPO RS13295
gene id: 246200:SPO_RS13295
uniprot id: Q5LQ75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

246200:SPO RS16190
gene id: 246200:SPO_RS16190
uniprot id: Q5LNK7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

246200:SPO RS03635
gene id: 246200:SPO_RS03635
uniprot id: Q5LVI1
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

246200:SPO RS09735
gene id: 246200:SPO_RS09735
uniprot id: Q5LS52
names: Similarity
messages: Belongs to the CFA/CMAS family.

246200:SPO RS14505
gene id: 246200:SPO_RS14505
uniprot id: Q5LPJ1
names: Similarity
messages: Belongs to the peptidase M24B family.

246200:SPO RS20585
gene id: 246200:SPO_RS20585
uniprot id: Q5LL78
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS08965
gene id: 246200:SPO_RS08965
uniprot id: Q5LSK4
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

246200:SPO RS18590
gene id: 246200:SPO_RS18590
uniprot id: Q5LM95
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS07555
gene id: 246200:SPO_RS07555
uniprot id: Q5LTD1
names: Similarity
messages: Belongs to the CFA/CMAS family.

246200:SPO RS01780
gene id: 246200:SPO_RS01780
uniprot id: Q5LXE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

246200:SPO RS05350
gene id: 246200:SPO_RS05350
uniprot id: Q5LUK0
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS09480
gene id: 246200:SPO_RS09480
uniprot id: Q5LSA3
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

246200:SPO RS16430
gene id: 246200:SPO_RS16430
uniprot id: Q5LNG1
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

246200:SPO RS11540
gene id: 246200:SPO_RS11540
uniprot id: Q5LR55
names: Similarity
messages: Belongs to the fabD family.

246200:SPO RS06335
gene id: 246200:SPO_RS06335
uniprot id: Q5LU15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

246200:SPO RS17770
gene id: 246200:SPO_RS17770
uniprot id: Q5LMQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

246200:SPO RS19410
gene id: 246200:SPO_RS19410
uniprot id: Q5LLU6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

246200:SPO RS04550
gene id: 246200:SPO_RS04550
uniprot id: Q5LUZ9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

246200:SPO RS11740
gene id: 246200:SPO_RS11740
uniprot id: Q5LR16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

246200:SPO RS00155
gene id: 246200:SPO_RS00155
uniprot id: Q5LWI9
names: Similarity
messages: Belongs to the YkuD family.

246200:SPO RS07835
gene id: 246200:SPO_RS07835
uniprot id: Q5LT75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

246200:SPO RS04455
gene id: 246200:SPO_RS04455
uniprot id: Q5LV18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

246200:SPO RS01265
gene id: 246200:SPO_RS01265
uniprot id: Q5LX41
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

246200:SPO RS04120
gene id: 246200:SPO_RS04120
uniprot id: Q5LV85
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

246200:SPO RS13255
gene id: 246200:SPO_RS13255
uniprot id: Q5LQ83
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

246200:SPO RS03905
gene id: 246200:SPO_RS03905
uniprot id: Q5LVC8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

246200:SPO RS20925
gene id: 246200:SPO_RS20925
uniprot id: Q5LL11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

246200:SPO RS21430
gene id: 246200:SPO_RS21430
uniprot id: Q5LKR3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

246200:SPO RS08770
gene id: 246200:SPO_RS08770
uniprot id: Q5LSP2
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

246200:SPO RS18650
gene id: 246200:SPO_RS18650
uniprot id: Q5LM87
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

246200:SPO RS15990
gene id: 246200:SPO_RS15990
uniprot id: Q5LNP7
names: Subunit
messages: Homotetramer.

246200:SPO RS21165
gene id: 246200:SPO_RS21165
uniprot id: Q5LKW3
names: Function
names: Similarity
messages: Belongs to the proline racemase family.
messages: Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp). Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate. Displays no proline racemase activity.

246200:SPO RS01230
gene id: 246200:SPO_RS01230
uniprot id: Q5LX30
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS04370
gene id: 246200:SPO_RS04370
uniprot id: Q5LV35
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS13690
gene id: 246200:SPO_RS13690
uniprot id: Q5LPZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS01215
gene id: 246200:SPO_RS01215
uniprot id: Q5LX33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

246200:SPO RS08840
gene id: 246200:SPO_RS08840
uniprot id: Q5LSN0
names: Similarity
messages: Belongs to the pirin family.

246200:SPO RS11400
gene id: 246200:SPO_RS11400
uniprot id: Q5LR82
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

246200:SPO RS12030
gene id: 246200:SPO_RS12030
uniprot id: Q5LQW2
names: Similarity
messages: Belongs to the universal stress protein A family.

246200:SPO RS10025
gene id: 246200:SPO_RS10025
uniprot id: Q5LRZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

246200:SPO RS11600
gene id: 246200:SPO_RS11600
uniprot id: Q5LR43
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

246200:SPO RS09320
gene id: 246200:SPO_RS09320
uniprot id: Q5LSD6
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS15765
gene id: 246200:SPO_RS15765
uniprot id: Q5LNU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

246200:SPO RS02510
gene id: 246200:SPO_RS02510
uniprot id: Q5LW46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

246200:SPO RS13055
gene id: 246200:SPO_RS13055
uniprot id: Q5LQB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

246200:SPO RS01170
gene id: 246200:SPO_RS01170
uniprot id: Q5LX29
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

246200:SPO RS19160
gene id: 246200:SPO_RS19160
uniprot id: Q5LLZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

246200:SPO RS20960
gene id: 246200:SPO_RS20960
uniprot id: Q5LL04
names: Similarity
messages: Belongs to the Ahb/Nir family.

246200:SPO RS20625
gene id: 246200:SPO_RS20625
uniprot id: Q5LL70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

246200:SPO RS04400
gene id: 246200:SPO_RS04400
uniprot id: Q5LV29
names: Subunit
messages: Homodimer.

246200:SPO RS05765
gene id: 246200:SPO_RS05765
uniprot id: Q5LUB8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS18925
gene id: 246200:SPO_RS18925
uniprot id: Q5LM35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

246200:SPO RS02580
gene id: 246200:SPO_RS02580
uniprot id: Q5LW32
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

246200:SPO RS01740
gene id: 246200:SPO_RS01740
uniprot id: Q5LXC8
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

246200:SPO RS01505
gene id: 246200:SPO_RS01505
uniprot id: Q5LX84
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

246200:SPO RS02495
gene id: 246200:SPO_RS02495
uniprot id: Q5LW49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

246200:SPO RS01035
gene id: 246200:SPO_RS01035
uniprot id: Q5LX01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

246200:SPO RS19115
gene id: 246200:SPO_RS19115
uniprot id: Q3V7J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

246200:SPO RS19125
gene id: 246200:SPO_RS19125
uniprot id: Q5LLZ6
names: Similarity
messages: Belongs to the glutamate synthase family.

246200:SPO RS00065
gene id: 246200:SPO_RS00065
uniprot id: Q5LWG8
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

246200:SPO RS19400
gene id: 246200:SPO_RS19400
uniprot id: Q5LLU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

246200:SPO RS07940
gene id: 246200:SPO_RS07940
uniprot id: Q5LT54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

246200:SPO RS19470
gene id: 246200:SPO_RS19470
uniprot id: Q5LLT4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

246200:SPO RS08330
gene id: 246200:SPO_RS08330
uniprot id: Q5LSX6
names: Similarity
messages: Belongs to the virb1 family.

246200:SPO RS21085
gene id: 246200:SPO_RS21085
uniprot id: Q5LKX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS22075
gene id: 246200:SPO_RS22075
uniprot id: Q5LKD6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

246200:SPO RS18070
gene id: 246200:SPO_RS18070
uniprot id: Q5LMJ6
names: Similarity
messages: Belongs to the RNase T2 family.

246200:SPO RS05895
gene id: 246200:SPO_RS05895
uniprot id: Q5LU92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

246200:SPO RS19860
gene id: 246200:SPO_RS19860
uniprot id: Q5LLM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

246200:SPO RS20085
gene id: 246200:SPO_RS20085
uniprot id: Q5LLG5
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

246200:SPO RS01095
gene id: 246200:SPO_RS01095
uniprot id: Q5LX07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

246200:SPO RS20640
gene id: 246200:SPO_RS20640
uniprot id: Q5LL67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS06540
gene id: 246200:SPO_RS06540
uniprot id: Q5LTX6
names: Similarity
messages: Belongs to the AHA1 family.

246200:SPO RS03100
gene id: 246200:SPO_RS03100
uniprot id: Q5LVT1
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

246200:SPO RS02350
gene id: 246200:SPO_RS02350
uniprot id: Q5LW76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

246200:SPO RS04860
gene id: 246200:SPO_RS04860
uniprot id: Q5LUT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

246200:SPO RS07060
gene id: 246200:SPO_RS07060
uniprot id: Q5LTN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

246200:SPO RS01260
gene id: 246200:SPO_RS01260
uniprot id: Q5LX42
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

246200:SPO RS19130
gene id: 246200:SPO_RS19130
uniprot id: Q5LLZ5
names: Similarity
messages: Belongs to the Gfa family.

246200:SPO RS09335
gene id: 246200:SPO_RS09335
uniprot id: Q5LSD3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

246200:SPO RS08445
gene id: 246200:SPO_RS08445
uniprot id: Q5LSV4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.

246200:SPO RS16170
gene id: 246200:SPO_RS16170
uniprot id: Q5LNL1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS06500
gene id: 246200:SPO_RS06500
uniprot id: Q5LTY4
names: Similarity
messages: Belongs to the ArsC family.

246200:SPO RS14860
gene id: 246200:SPO_RS14860
uniprot id: Q5LPB8
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

246200:SPO RS09555
gene id: 246200:SPO_RS09555
uniprot id: Q5LS88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

246200:SPO RS15885
gene id: 246200:SPO_RS15885
uniprot id: Q5LNR8
names: Similarity
messages: Belongs to the peptidase S58 family.

246200:SPO RS05750
gene id: 246200:SPO_RS05750
uniprot id: Q5LUC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS14050
gene id: 246200:SPO_RS14050
uniprot id: Q5LPT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

246200:SPO RS13125
gene id: 246200:SPO_RS13125
uniprot id: Q5LQA6
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

246200:SPO RS15535
gene id: 246200:SPO_RS15535
uniprot id: Q5LNY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

246200:SPO RS17540
gene id: 246200:SPO_RS17540
uniprot id: Q5LMU9
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

246200:SPO RS02455
gene id: 246200:SPO_RS02455
uniprot id: Q5LW56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

246200:SPO RS14575
gene id: 246200:SPO_RS14575
uniprot id: Q5LPH7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

246200:SPO RS20915
gene id: 246200:SPO_RS20915
uniprot id: Q5LL13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

246200:SPO RS13270
gene id: 246200:SPO_RS13270
uniprot id: Q5LQ80
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

246200:SPO RS14310
gene id: 246200:SPO_RS14310
uniprot id: Q5LPN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

246200:SPO RS14330
gene id: 246200:SPO_RS14330
uniprot id: Q5LPM7
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS14585
gene id: 246200:SPO_RS14585
uniprot id: Q5LPH5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

246200:SPO RS15925
gene id: 246200:SPO_RS15925
uniprot id: Q5LNR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

246200:SPO RS07090
gene id: 246200:SPO_RS07090
uniprot id: Q5LTM4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

246200:SPO RS15440
gene id: 246200:SPO_RS15440
uniprot id: Q5LP06
names: Subcellular Location Annotation
messages: Cell inner membrane

246200:SPO RS12625
gene id: 246200:SPO_RS12625
uniprot id: Q5LQK2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

246200:SPO RS05910
gene id: 246200:SPO_RS05910
uniprot id: Q5LU89
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS00545
gene id: 246200:SPO_RS00545
uniprot id: Q5LWQ6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

246200:SPO RS02190
gene id: 246200:SPO_RS02190
uniprot id: Q5LWA9
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS19165
gene id: 246200:SPO_RS19165
uniprot id: Q5LLY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

246200:SPO RS10090
gene id: 246200:SPO_RS10090
uniprot id: Q5LRY1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

246200:SPO RS11715
gene id: 246200:SPO_RS11715
uniprot id: Q5LR20
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

246200:SPO RS16245
gene id: 246200:SPO_RS16245
uniprot id: Q5LNJ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

246200:SPO RS04830
gene id: 246200:SPO_RS04830
uniprot id: Q5LUU0
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

246200:SPO RS10580
gene id: 246200:SPO_RS10580
uniprot id: Q5LRN9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

246200:SPO RS20895
gene id: 246200:SPO_RS20895
uniprot id: Q5LL17
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS02050
gene id: 246200:SPO_RS02050
uniprot id: Q5LWD7
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

246200:SPO RS18495
gene id: 246200:SPO_RS18495
uniprot id: Q5LMB4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

246200:SPO RS18425
gene id: 246200:SPO_RS18425
uniprot id: Q5LMC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

246200:SPO RS18270
gene id: 246200:SPO_RS18270
uniprot id: Q5LMF7
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

246200:SPO RS11970
gene id: 246200:SPO_RS11970
uniprot id: Q5LQX3
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

246200:SPO RS09795
gene id: 246200:SPO_RS09795
uniprot id: Q5LS41
names: Similarity
messages: Belongs to the YkuD family.

246200:SPO RS03370
gene id: 246200:SPO_RS03370
uniprot id: Q5LVN3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

246200:SPO RS20390
gene id: 246200:SPO_RS20390
uniprot id: Q5LLB4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

246200:SPO RS15580
gene id: 246200:SPO_RS15580
uniprot id: Q5LNX8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.

246200:SPO RS11580
gene id: 246200:SPO_RS11580
uniprot id: Q5LR47
names: Similarity
messages: Belongs to the virb1 family.

246200:SPO RS13785
gene id: 246200:SPO_RS13785
uniprot id: Q5LPX8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

246200:SPO RS20595
gene id: 246200:SPO_RS20595
uniprot id: Q5LL76
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

246200:SPO RS15085
gene id: 246200:SPO_RS15085
uniprot id: Q5LP74
names: Similarity
messages: Belongs to the UPF0173 family.

246200:SPO RS20095
gene id: 246200:SPO_RS20095
uniprot id: Q5LLG3
names: Similarity
messages: Belongs to the DDAH family.

246200:SPO RS11895
gene id: 246200:SPO_RS11895
uniprot id: Q5LQY7
names: Similarity
messages: Belongs to the GcvT family.

246200:SPO RS00005
gene id: 246200:SPO_RS00005
uniprot id: Q5LWF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

246200:SPO RS00755
gene id: 246200:SPO_RS00755
uniprot id: Q5LWT8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

246200:SPO RS01680
gene id: 246200:SPO_RS01680
uniprot id: Q5LXC2
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

246200:SPO RS06700
gene id: 246200:SPO_RS06700
uniprot id: Q5LTU8
names: Similarity
messages: Belongs to the nitrile hydratase subunit alpha family.

246200:SPO RS19010
gene id: 246200:SPO_RS19010
uniprot id: Q5LM18
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

246200:SPO RS17165
gene id: 246200:SPO_RS17165
uniprot id: Q5LN23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

246200:SPO RS02600
gene id: 246200:SPO_RS02600
uniprot id: Q5LW28
names: Function
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

246200:SPO RS10375
gene id: 246200:SPO_RS10375
uniprot id: Q5LRT0
names: Activity Regulation
names: Disruption Phenotype
names: Function
names: Similarity
names: Subunit
messages: Activated by LiCl and NH(4)Cl. Inhibited by dimethylsulfoniopropionate (DMSP). MMPA concentrations above 2 mM relieve the DMSP inhibition and 80% of activity is regained at an MMPA concentration of 8 mM.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Cells lacking this gene show a delayed growth on methylmercaptopropionate (MMPA).
messages: Homodimer.
messages: Involved in the assimilation of dimethylsulphoniopropionate (DMSP), an important compound in the fixation of carbon in marine phytoplankton. Catalyzes the ATP-dependent ligation of methylmercaptopropionate (MMPA) and CoA to yield methylmercaptopropionate-CoA (MMPA-CoA) (PubMed:21562561, PubMed:24443527). It is also active with short-chain-fatty-acid (carboxylic acids up to six carbons in length) (PubMed:21562561, PubMed:24443527).

246200:SPO RS10820
gene id: 246200:SPO_RS10820
uniprot id: Q5LRJ3
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

246200:SPO RS03945
gene id: 246200:SPO_RS03945
uniprot id: Q5LVC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS03695
gene id: 246200:SPO_RS03695
uniprot id: Q5LVH0
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

246200:SPO RS17340
gene id: 246200:SPO_RS17340
uniprot id: Q5LMY7
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

246200:SPO RS13215
gene id: 246200:SPO_RS13215
uniprot id: Q5LQ90
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

246200:SPO RS12345
gene id: 246200:SPO_RS12345
uniprot id: Q5LQQ8
names: Similarity
messages: Belongs to the UxaA family.

246200:SPO RS15755
gene id: 246200:SPO_RS15755
uniprot id: Q5LNU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

246200:SPO RS13010
gene id: 246200:SPO_RS13010
uniprot id: Q5LQC7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

246200:SPO RS08465
gene id: 246200:SPO_RS08465
uniprot id: Q5LSV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

246200:SPO RS16275
gene id: 246200:SPO_RS16275
uniprot id: Q5LNJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

246200:SPO RS07160
gene id: 246200:SPO_RS07160
uniprot id: Q5LTL1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

246200:SPO RS16640
gene id: 246200:SPO_RS16640
uniprot id: Q5LNC6
names: Similarity
messages: Belongs to the sulfatase family.

246200:SPO RS10420
gene id: 246200:SPO_RS10420
uniprot id: Q5LRS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 2 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.

246200:SPO RS09235
gene id: 246200:SPO_RS09235
uniprot id: Q5LSF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS13505
gene id: 246200:SPO_RS13505
uniprot id: Q5LQ34
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

246200:SPO RS22100
gene id: 246200:SPO_RS22100
uniprot id: Q5LVX3
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

246200:SPO RS05090
gene id: 246200:SPO_RS05090
uniprot id: Q5LUP2
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

246200:SPO RS13565
gene id: 246200:SPO_RS13565
uniprot id: Q5LQ22
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

246200:SPO RS16970
gene id: 246200:SPO_RS16970
uniprot id: Q5LN62
names: Similarity
messages: Belongs to the YciI family.

246200:SPO RS03715
gene id: 246200:SPO_RS03715
uniprot id: Q5LVG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS16765
gene id: 246200:SPO_RS16765
uniprot id: Q5LNA1
names: Cofactor
messages: Binds 1 zinc ion per subunit.

246200:SPO RS19425
gene id: 246200:SPO_RS19425
uniprot id: Q5LLU3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

246200:SPO RS10180
gene id: 246200:SPO_RS10180
uniprot id: Q5LRW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

246200:SPO RS05020
gene id: 246200:SPO_RS05020
uniprot id: Q5LUQ6
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

246200:SPO RS10315
gene id: 246200:SPO_RS10315
uniprot id: Q5LRU1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

246200:SPO RS04005
gene id: 246200:SPO_RS04005
uniprot id: Q5LVA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

246200:SPO RS22010
gene id: 246200:SPO_RS22010
uniprot id: Q5LKF0
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS08070
gene id: 246200:SPO_RS08070
uniprot id: Q5LT28
names: Similarity
messages: Belongs to the GcvT family.

246200:SPO RS19680
gene id: 246200:SPO_RS19680
uniprot id: Q5LLP4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

246200:SPO RS14990
gene id: 246200:SPO_RS14990
uniprot id: Q5LP92
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

246200:SPO RS09830
gene id: 246200:SPO_RS09830
uniprot id: Q5LS34
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS10600
gene id: 246200:SPO_RS10600
uniprot id: Q5LRN5
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.

246200:SPO RS15685
gene id: 246200:SPO_RS15685
uniprot id: Q5LNV8
names: Similarity
messages: Belongs to the peptidase A24 family.

246200:SPO RS22170
gene id: 246200:SPO_RS22170
uniprot id: Q5LT80
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

246200:SPO RS03380
gene id: 246200:SPO_RS03380
uniprot id: Q5LVN1
names: Function
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.

246200:SPO RS00020
gene id: 246200:SPO_RS00020
uniprot id: Q5LWG0
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

246200:SPO RS14685
gene id: 246200:SPO_RS14685
uniprot id: Q5LPF4
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS04465
gene id: 246200:SPO_RS04465
uniprot id: Q5LV16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

246200:SPO RS11145
gene id: 246200:SPO_RS11145
uniprot id: Q5LRD1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

246200:SPO RS17600
gene id: 246200:SPO_RS17600
uniprot id: Q5LMT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS19020
gene id: 246200:SPO_RS19020
uniprot id: Q5LM16
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS06495
gene id: 246200:SPO_RS06495
uniprot id: Q5LTY5
names: Subcellular Location Annotation
messages: Cytoplasm

246200:SPO RS15380
gene id: 246200:SPO_RS15380
uniprot id: Q5LP18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

246200:SPO RS16025
gene id: 246200:SPO_RS16025
uniprot id: Q5LNP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

246200:SPO RS04660
gene id: 246200:SPO_RS04660
uniprot id: Q5LUX7
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS20965
gene id: 246200:SPO_RS20965
uniprot id: Q5LL03
names: Similarity
messages: Belongs to the Ahb/Nir family.

246200:SPO RS03665
gene id: 246200:SPO_RS03665
uniprot id: Q5LVH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

246200:SPO RS01130
gene id: 246200:SPO_RS01130
uniprot id: Q5LX18
names: Similarity
messages: Belongs to the AlaDH/PNT family.

246200:SPO RS19765
gene id: 246200:SPO_RS19765
uniprot id: Q5LLM8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

246200:SPO RS12465
gene id: 246200:SPO_RS12465
uniprot id: Q5LQN4
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS04855
gene id: 246200:SPO_RS04855
uniprot id: Q5LUT6
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

246200:SPO RS10760
gene id: 246200:SPO_RS10760
uniprot id: Q5LRK5
names: Similarity
messages: Belongs to the YjdM family.

246200:SPO RS10770
gene id: 246200:SPO_RS10770
uniprot id: Q5LRK3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

246200:SPO RS02490
gene id: 246200:SPO_RS02490
uniprot id: Q5LW50
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

246200:SPO RS15195
gene id: 246200:SPO_RS15195
uniprot id: Q5LP53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS13080
gene id: 246200:SPO_RS13080
uniprot id: Q3V7J4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

246200:SPO RS06385
gene id: 246200:SPO_RS06385
uniprot id: Q5LU07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

246200:SPO RS05645
gene id: 246200:SPO_RS05645
uniprot id: Q5LUE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

246200:SPO RS00900
gene id: 246200:SPO_RS00900
uniprot id: Q5LWX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

246200:SPO RS10805
gene id: 246200:SPO_RS10805
uniprot id: Q5LRJ6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

246200:SPO RS02700
gene id: 246200:SPO_RS02700
uniprot id: Q5LW08
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS15455
gene id: 246200:SPO_RS15455
uniprot id: Q5LP03
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

246200:SPO RS22040
gene id: 246200:SPO_RS22040
uniprot id: Q5LKE4
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

246200:SPO RS00305
gene id: 246200:SPO_RS00305
uniprot id: Q5LWL5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

246200:SPO RS12580
gene id: 246200:SPO_RS12580
uniprot id: Q5LQL1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

246200:SPO RS01765
gene id: 246200:SPO_RS01765
uniprot id: Q5LXC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

246200:SPO RS04835
gene id: 246200:SPO_RS04835
uniprot id: Q5LUT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

246200:SPO RS02505
gene id: 246200:SPO_RS02505
uniprot id: Q5LW47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

246200:SPO RS17435
gene id: 246200:SPO_RS17435
uniprot id: Q5LMW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

246200:SPO RS18920
gene id: 246200:SPO_RS18920
uniprot id: Q5LM36
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS00040
gene id: 246200:SPO_RS00040
uniprot id: Q5LWF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

246200:SPO RS00730
gene id: 246200:SPO_RS00730
uniprot id: Q5LWU3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

246200:SPO RS16560
gene id: 246200:SPO_RS16560
uniprot id: Q5LNE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

246200:SPO RS20070
gene id: 246200:SPO_RS20070
uniprot id: Q5LLG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

246200:SPO RS22045
gene id: 246200:SPO_RS22045
uniprot id: Q5LKE3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

246200:SPO RS10115
gene id: 246200:SPO_RS10115
uniprot id: Q5LRX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

246200:SPO RS20985
gene id: 246200:SPO_RS20985
uniprot id: Q5LKZ9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS21185
gene id: 246200:SPO_RS21185
uniprot id: Q5LKV9
names: Similarity
messages: Belongs to the SCO1/2 family.

246200:SPO RS17820
gene id: 246200:SPO_RS17820
uniprot id: Q5LMP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

246200:SPO RS18390
gene id: 246200:SPO_RS18390
uniprot id: Q5LMD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

246200:SPO RS18705
gene id: 246200:SPO_RS18705
uniprot id: Q5LM77
names: Similarity
messages: Belongs to the group II decarboxylase family.

246200:SPO RS20300
gene id: 246200:SPO_RS20300
uniprot id: Q5LLD1
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS01950
gene id: 246200:SPO_RS01950
uniprot id: Q5LXG7
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

246200:SPO RS06925
gene id: 246200:SPO_RS06925
uniprot id: Q5LTQ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

246200:SPO RS21720
gene id: 246200:SPO_RS21720
uniprot id: Q5LKK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS12915
gene id: 246200:SPO_RS12915
uniprot id: Q5LQE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS17355
gene id: 246200:SPO_RS17355
uniprot id: Q5LMY4
names: Similarity
messages: Belongs to the YkuD family.

246200:SPO RS09590
gene id: 246200:SPO_RS09590
uniprot id: Q5LS81
names: Similarity
messages: Belongs to the SAICAR synthetase family.

246200:SPO RS20090
gene id: 246200:SPO_RS20090
uniprot id: Q5LLG4
names: Similarity
messages: Belongs to the GcvT family.

246200:SPO RS15825
gene id: 246200:SPO_RS15825
uniprot id: Q5LNT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

246200:SPO RS17625
gene id: 246200:SPO_RS17625
uniprot id: Q5LMT2
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

246200:SPO RS12665
gene id: 246200:SPO_RS12665
uniprot id: Q5LQJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

246200:SPO RS12715
gene id: 246200:SPO_RS12715
uniprot id: Q5LQI5
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

246200:SPO RS09930
gene id: 246200:SPO_RS09930
uniprot id: Q5LS14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

246200:SPO RS10555
gene id: 246200:SPO_RS10555
uniprot id: Q5LRP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

246200:SPO RS10860
gene id: 246200:SPO_RS10860
uniprot id: Q5LRI6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

246200:SPO RS13030
gene id: 246200:SPO_RS13030
uniprot id: Q5LQC4
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS02695
gene id: 246200:SPO_RS02695
uniprot id: Q5LW09
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

246200:SPO RS17565
gene id: 246200:SPO_RS17565
uniprot id: Q5LMU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

246200:SPO RS14070
gene id: 246200:SPO_RS14070
uniprot id: Q5LPS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

246200:SPO RS21615
gene id: 246200:SPO_RS21615
uniprot id: Q5LKM9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS10070
gene id: 246200:SPO_RS10070
uniprot id: Q5LRY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

246200:SPO RS19335
gene id: 246200:SPO_RS19335
uniprot id: Q5LLW1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

246200:SPO RS03065
gene id: 246200:SPO_RS03065
uniprot id: Q5LVT8
names: Similarity
messages: Belongs to the proline racemase family.

246200:SPO RS09910
gene id: 246200:SPO_RS09910
uniprot id: Q5LS18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

246200:SPO RS08360
gene id: 246200:SPO_RS08360
uniprot id: Q5LSX0
names: Subcellular Location Annotation
messages: Cell inner membrane

246200:SPO RS04075
gene id: 246200:SPO_RS04075
uniprot id: Q5LV94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

246200:SPO RS03285
gene id: 246200:SPO_RS03285
uniprot id: Q5LVQ0
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS09380
gene id: 246200:SPO_RS09380
uniprot id: Q5LSC4
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

246200:SPO RS07320
gene id: 246200:SPO_RS07320
uniprot id: Q5LTH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3-dehydrocarnitine.
messages: Cytoplasm
messages: Homodimer.
messages: In the N-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. L-carnitine dehydrogenase subfamily.

246200:SPO RS18915
gene id: 246200:SPO_RS18915
uniprot id: Q5LM37
names: Similarity
messages: Belongs to the MlaA family.

246200:SPO RS07480
gene id: 246200:SPO_RS07480
uniprot id: Q5LTE6
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

246200:SPO RS00865
gene id: 246200:SPO_RS00865
uniprot id: Q5LWW6
names: Similarity
messages: Belongs to the virb1 family.

246200:SPO RS03825
gene id: 246200:SPO_RS03825
uniprot id: Q5LVE4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

246200:SPO RS01400
gene id: 246200:SPO_RS01400
uniprot id: Q5LX69
names: Subcellular Location Annotation
messages: Cell membrane

246200:SPO RS17455
gene id: 246200:SPO_RS17455
uniprot id: Q5LMW4
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

246200:SPO RS08750
gene id: 246200:SPO_RS08750
uniprot id: Q5LSP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

246200:SPO RS07935
gene id: 246200:SPO_RS07935
uniprot id: Q5LNV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

246200:SPO RS18900
gene id: 246200:SPO_RS18900
uniprot id: Q5LM40
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

246200:SPO RS17640
gene id: 246200:SPO_RS17640
uniprot id: Q5LMS9
names: Similarity
messages: Belongs to the peptidase S1B family.

246200:SPO RS03895
gene id: 246200:SPO_RS03895
uniprot id: Q5LVD0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

246200:SPO RS11080
gene id: 246200:SPO_RS11080
uniprot id: Q5LRE4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

246200:SPO RS11105
gene id: 246200:SPO_RS11105
uniprot id: Q5LRD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

246200:SPO RS19050
gene id: 246200:SPO_RS19050
uniprot id: Q5LM10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

246200:SPO RS03020
gene id: 246200:SPO_RS03020
uniprot id: Q5LVU7
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

246200:SPO RS10695
gene id: 246200:SPO_RS10695
uniprot id: Q5LRL6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

246200:SPO RS04975
gene id: 246200:SPO_RS04975
uniprot id: Q5LUR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

246200:SPO RS00070
gene id: 246200:SPO_RS00070
uniprot id: Q5LWG7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

246200:SPO RS18990
gene id: 246200:SPO_RS18990
uniprot id: Q5LM22
names: Similarity
messages: Belongs to the glutathione peroxidase family.

246200:SPO RS08620
gene id: 246200:SPO_RS08620
uniprot id: Q5LSR7
names: Similarity
messages: Belongs to the PrpD family.

246200:SPO RS14450
gene id: 246200:SPO_RS14450
uniprot id: Q5LPK2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

246200:SPO RS14000
gene id: 246200:SPO_RS14000
uniprot id: Q5LPU3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

246200:SPO RS15770
gene id: 246200:SPO_RS15770
uniprot id: Q5LNU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

246200:SPO RS10665
gene id: 246200:SPO_RS10665
uniprot id: Q5LRM2
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

246200:SPO RS20800
gene id: 246200:SPO_RS20800
uniprot id: Q5LL36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

246200:SPO RS10735
gene id: 246200:SPO_RS10735
uniprot id: Q5LRL0
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS09325
gene id: 246200:SPO_RS09325
uniprot id: Q5LSD5
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS20890
gene id: 246200:SPO_RS20890
uniprot id: Q5LL18
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

246200:SPO RS04840
gene id: 246200:SPO_RS04840
uniprot id: Q5LUT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

246200:SPO RS06775
gene id: 246200:SPO_RS06775
uniprot id: Q5LTT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

246200:SPO RS12245
gene id: 246200:SPO_RS12245
uniprot id: Q5LQS8
names: Similarity
messages: Belongs to the IlvD/Edd family.

246200:SPO RS07240
gene id: 246200:SPO_RS07240
uniprot id: Q5LTJ5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

246200:SPO RS00630
gene id: 246200:SPO_RS00630
uniprot id: Q5LWS7
names: Subcellular Location Annotation
messages: Membrane

246200:SPO RS21620
gene id: 246200:SPO_RS21620
uniprot id: Q5LKM8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

246200:SPO RS19740
gene id: 246200:SPO_RS19740
uniprot id: Q5LLN3
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

246200:SPO RS18015
gene id: 246200:SPO_RS18015
uniprot id: Q5LMK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

246200:SPO RS04110
gene id: 246200:SPO_RS04110
uniprot id: Q5LV87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

246200:SPO RS06125
gene id: 246200:SPO_RS06125
uniprot id: Q5LU51
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

246200:SPO RS08320
gene id: 246200:SPO_RS08320
uniprot id: Q5LSX8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

246200:SPO RS21400
gene id: 246200:SPO_RS21400
uniprot id: Q5LKR8
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

246200:SPO RS04875
gene id: 246200:SPO_RS04875
uniprot id: Q5LUT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

246200:SPO RS21380
gene id: 246200:SPO_RS21380
uniprot id: Q5LKS2
names: Similarity
messages: Belongs to the TPP enzyme family.

246200:SPO RS09620
gene id: 246200:SPO_RS09620
uniprot id: Q5LS75
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

246200:SPO RS03090
gene id: 246200:SPO_RS03090
uniprot id: Q5LVT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

246200:SPO RS00540
gene id: 246200:SPO_RS00540
uniprot id: Q5LWQ8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

246200:SPO RS02135
gene id: 246200:SPO_RS02135
uniprot id: Q5LWC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

246200:SPO RS15295
gene id: 246200:SPO_RS15295
uniprot id: Q5LP35
names: Similarity
messages: Belongs to the thioesterase PaaI family.

246200:SPO RS21035
gene id: 246200:SPO_RS21035
uniprot id: Q5LKY9
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

246200:SPO RS05470
gene id: 246200:SPO_RS05470
uniprot id: Q5LUH6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

246200:SPO RS00625
gene id: 246200:SPO_RS00625
uniprot id: Q5LWS8
names: Similarity
messages: Belongs to the YggT family.