243275:TDE RS08300
gene id: 243275:TDE_RS08300
uniprot id: Q73LX9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

243275:TDE RS01190
gene id: 243275:TDE_RS01190
uniprot id: Q73R49
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS10520
gene id: 243275:TDE_RS10520
uniprot id: Q73KJ2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

243275:TDE RS03720
gene id: 243275:TDE_RS03720
uniprot id: Q73PN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

243275:TDE RS06905
gene id: 243275:TDE_RS06905
uniprot id: P60920
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

243275:TDE RS08250
gene id: 243275:TDE_RS08250
uniprot id: Q73LY9
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

243275:TDE RS02285
gene id: 243275:TDE_RS02285
uniprot id: Q73QH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

243275:TDE RS12905
gene id: 243275:TDE_RS12905
uniprot id: Q73J32
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

243275:TDE RS06565
gene id: 243275:TDE_RS06565
uniprot id: Q73MY7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

243275:TDE RS11240
gene id: 243275:TDE_RS11240
uniprot id: Q73K42
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS09860
gene id: 243275:TDE_RS09860
uniprot id: Q73KY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

243275:TDE RS03755
gene id: 243275:TDE_RS03755
uniprot id: Q73PM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

243275:TDE RS00905
gene id: 243275:TDE_RS00905
uniprot id: Q73RA3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

243275:TDE RS11265
gene id: 243275:TDE_RS11265
uniprot id: Q73JN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

243275:TDE RS04365
gene id: 243275:TDE_RS04365
uniprot id: Q73P96
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

243275:TDE RS11750
gene id: 243275:TDE_RS11750
uniprot id: Q73JU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

243275:TDE RS11085
gene id: 243275:TDE_RS11085
uniprot id: Q73K75
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

243275:TDE RS05410
gene id: 243275:TDE_RS05410
uniprot id: Q73NM2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

243275:TDE RS03135
gene id: 243275:TDE_RS03135
uniprot id: Q73PZ4
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS12570
gene id: 243275:TDE_RS12570
uniprot id: Q73JA6
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

243275:TDE RS01410
gene id: 243275:TDE_RS01410
uniprot id: Q73R06
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS04430
gene id: 243275:TDE_RS04430
uniprot id: Q73P78
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS08365
gene id: 243275:TDE_RS08365
uniprot id: Q73LW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

243275:TDE RS11810
gene id: 243275:TDE_RS11810
uniprot id: Q73JV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

243275:TDE RS04020
gene id: 243275:TDE_RS04020
uniprot id: Q73PG5
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS01570
gene id: 243275:TDE_RS01570
uniprot id: Q73QX2
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS10955
gene id: 243275:TDE_RS10955
uniprot id: Q73K99
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

243275:TDE RS07790
gene id: 243275:TDE_RS07790
uniprot id: Q73M80
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

243275:TDE RS11685
gene id: 243275:TDE_RS11685
uniprot id: Q73JT3
names: Similarity
messages: Belongs to the carbamate kinase family.

243275:TDE RS11030
gene id: 243275:TDE_RS11030
uniprot id: Q73K85
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

243275:TDE RS03215
gene id: 243275:TDE_RS03215
uniprot id: Q73PX9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

243275:TDE RS01230
gene id: 243275:TDE_RS01230
uniprot id: Q73R42
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS11040
gene id: 243275:TDE_RS11040
uniprot id: Q73K83
names: Similarity
messages: Belongs to the peptidase M29 family.

243275:TDE RS02775
gene id: 243275:TDE_RS02775
uniprot id: P61348
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

243275:TDE RS08370
gene id: 243275:TDE_RS08370
uniprot id: Q73LW6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

243275:TDE RS11745
gene id: 243275:TDE_RS11745
uniprot id: Q73JU6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

243275:TDE RS08065
gene id: 243275:TDE_RS08065
uniprot id: Q73M28
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

243275:TDE RS11060
gene id: 243275:TDE_RS11060
uniprot id: Q73K78
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

243275:TDE RS05130
gene id: 243275:TDE_RS05130
uniprot id: Q73NS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

243275:TDE RS02340
gene id: 243275:TDE_RS02340
uniprot id: Q73QF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

243275:TDE RS10495
gene id: 243275:TDE_RS10495
uniprot id: Q73KJ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

243275:TDE RS11625
gene id: 243275:TDE_RS11625
uniprot id: Q73JP8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

243275:TDE RS04445
gene id: 243275:TDE_RS04445
uniprot id: Q73P75
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS04600
gene id: 243275:TDE_RS04600
uniprot id: Q73P41
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243275:TDE RS07425
gene id: 243275:TDE_RS07425
uniprot id: Q73MF9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

243275:TDE RS09005
gene id: 243275:TDE_RS09005
uniprot id: Q73LH0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

243275:TDE RS03730
gene id: 243275:TDE_RS03730
uniprot id: Q73PM8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

243275:TDE RS11695
gene id: 243275:TDE_RS11695
uniprot id: Q73JT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

243275:TDE RS11870
gene id: 243275:TDE_RS11870
uniprot id: Q73JW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

243275:TDE RS05010
gene id: 243275:TDE_RS05010
uniprot id: Q73NV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

243275:TDE RS04370
gene id: 243275:TDE_RS04370
uniprot id: Q73P94
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS06700
gene id: 243275:TDE_RS06700
uniprot id: P60974
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

243275:TDE RS04810
gene id: 243275:TDE_RS04810
uniprot id: Q73NZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

243275:TDE RS11070
gene id: 243275:TDE_RS11070
uniprot id: Q73K76
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

243275:TDE RS01105
gene id: 243275:TDE_RS01105
uniprot id: Q73R66
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

243275:TDE RS06360
gene id: 243275:TDE_RS06360
uniprot id: Q73N26
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

243275:TDE RS07415
gene id: 243275:TDE_RS07415
uniprot id: Q73MG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

243275:TDE RS04700
gene id: 243275:TDE_RS04700
uniprot id: Q73P19
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

243275:TDE RS05045
gene id: 243275:TDE_RS05045
uniprot id: Q73NU8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243275:TDE RS03585
gene id: 243275:TDE_RS03585
uniprot id: Q73PR0
names: Similarity
messages: Belongs to the YoeB family.

243275:TDE RS03210
gene id: 243275:TDE_RS03210
uniprot id: Q73PY0
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

243275:TDE RS03020
gene id: 243275:TDE_RS03020
uniprot id: Q73Q16
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

243275:TDE RS11430
gene id: 243275:TDE_RS11430
uniprot id: Q73JJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

243275:TDE RS04850
gene id: 243275:TDE_RS04850
uniprot id: Q73NY7
names: Similarity
messages: Belongs to the hemerythrin family.

243275:TDE RS05150
gene id: 243275:TDE_RS05150
uniprot id: Q73NS4
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

243275:TDE RS02300
gene id: 243275:TDE_RS02300
uniprot id: Q73QG7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

243275:TDE RS11335
gene id: 243275:TDE_RS11335
uniprot id: Q73JL6
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

243275:TDE RS05750
gene id: 243275:TDE_RS05750
uniprot id: P62477
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

243275:TDE RS04720
gene id: 243275:TDE_RS04720
uniprot id: Q73P16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

243275:TDE RS05630
gene id: 243275:TDE_RS05630
uniprot id: Q73NH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

243275:TDE RS09070
gene id: 243275:TDE_RS09070
uniprot id: Q73LF4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

243275:TDE RS08125
gene id: 243275:TDE_RS08125
uniprot id: Q73M14
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

243275:TDE RS09255
gene id: 243275:TDE_RS09255
uniprot id: Q73LB5
names: Similarity
messages: Belongs to the BMP lipoprotein family.

243275:TDE RS04415
gene id: 243275:TDE_RS04415
uniprot id: Q73P83
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS00505
gene id: 243275:TDE_RS00505
uniprot id: Q73RI7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

243275:TDE RS00090
gene id: 243275:TDE_RS00090
uniprot id: Q73RR8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

243275:TDE RS01820
gene id: 243275:TDE_RS01820
uniprot id: Q73QS1
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS04375
gene id: 243275:TDE_RS04375
uniprot id: Q73P93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).

243275:TDE RS11420
gene id: 243275:TDE_RS11420
uniprot id: Q73JJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

243275:TDE RS09515
gene id: 243275:TDE_RS09515
uniprot id: Q73L57
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS07635
gene id: 243275:TDE_RS07635
uniprot id: P61987
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

243275:TDE RS12795
gene id: 243275:TDE_RS12795
uniprot id: Q73J58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

243275:TDE RS08395
gene id: 243275:TDE_RS08395
uniprot id: Q73LW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

243275:TDE RS09880
gene id: 243275:TDE_RS09880
uniprot id: Q73KY2
names: Similarity
messages: Belongs to the UMP kinase family.

243275:TDE RS00790
gene id: 243275:TDE_RS00790
uniprot id: Q73RC7
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

243275:TDE RS08355
gene id: 243275:TDE_RS08355
uniprot id: Q73LW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

243275:TDE RS00450
gene id: 243275:TDE_RS00450
uniprot id: Q73RK0
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS07270
gene id: 243275:TDE_RS07270
uniprot id: Q73MJ0
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS04665
gene id: 243275:TDE_RS04665
uniprot id: Q73P28
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

243275:TDE RS13070
gene id: 243275:TDE_RS13070
uniprot id: Q73J01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

243275:TDE RS04230
gene id: 243275:TDE_RS04230
uniprot id: Q73PC4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

243275:TDE RS01135
gene id: 243275:TDE_RS01135
uniprot id: Q73R60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

243275:TDE RS06125
gene id: 243275:TDE_RS06125
uniprot id: Q73N77
names: Similarity
messages: Belongs to the UPF0340 family.

243275:TDE RS12650
gene id: 243275:TDE_RS12650
uniprot id: Q3V8B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

243275:TDE RS03955
gene id: 243275:TDE_RS03955
uniprot id: Q73PI1
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS01405
gene id: 243275:TDE_RS01405
uniprot id: Q73R07
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS13015
gene id: 243275:TDE_RS13015
uniprot id: F7ITV4
names: Similarity
messages: Belongs to the MotB family.

243275:TDE RS08380
gene id: 243275:TDE_RS08380
uniprot id: Q73LW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

243275:TDE RS09790
gene id: 243275:TDE_RS09790
uniprot id: Q73L00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

243275:TDE RS08180
gene id: 243275:TDE_RS08180
uniprot id: Q73M03
names: Function
names: Similarity
messages: Belongs to the bacterial histone-like protein family.
messages: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.

243275:TDE RS03085
gene id: 243275:TDE_RS03085
uniprot id: Q73Q03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

243275:TDE RS03925
gene id: 243275:TDE_RS03925
uniprot id: Q73PI7
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS03620
gene id: 243275:TDE_RS03620
uniprot id: Q73PQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

243275:TDE RS11315
gene id: 243275:TDE_RS11315
uniprot id: P61474
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

243275:TDE RS13000
gene id: 243275:TDE_RS13000
uniprot id: F7ITY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

243275:TDE RS01490
gene id: 243275:TDE_RS01490
uniprot id: Q73QY8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

243275:TDE RS00595
gene id: 243275:TDE_RS00595
uniprot id: Q73RG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

243275:TDE RS02330
gene id: 243275:TDE_RS02330
uniprot id: Q73QG1
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

243275:TDE RS11310
gene id: 243275:TDE_RS11310
uniprot id: Q73JM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

243275:TDE RS12990
gene id: 243275:TDE_RS12990
uniprot id: Q9X5A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Plays a role in the flagellum-specific transport system.

243275:TDE RS05880
gene id: 243275:TDE_RS05880
uniprot id: Q73ND1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

243275:TDE RS04035
gene id: 243275:TDE_RS04035
uniprot id: Q73PG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

243275:TDE RS12670
gene id: 243275:TDE_RS12670
uniprot id: Q73J84
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

243275:TDE RS04180
gene id: 243275:TDE_RS04180
uniprot id: Q73PD5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

243275:TDE RS05825
gene id: 243275:TDE_RS05825
uniprot id: Q73NE1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

243275:TDE RS01600
gene id: 243275:TDE_RS01600
uniprot id: Q73QW6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Binds crRNA and tracrRNA.

243275:TDE RS07205
gene id: 243275:TDE_RS07205
uniprot id: Q73MK4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

243275:TDE RS04625
gene id: 243275:TDE_RS04625
uniprot id: Q73P36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

243275:TDE RS11120
gene id: 243275:TDE_RS11120
uniprot id: Q73K68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

243275:TDE RS03265
gene id: 243275:TDE_RS03265
uniprot id: Q73PX0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243275:TDE RS07160
gene id: 243275:TDE_RS07160
uniprot id: Q73ML2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

243275:TDE RS05110
gene id: 243275:TDE_RS05110
uniprot id: F7ITG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

243275:TDE RS10395
gene id: 243275:TDE_RS10395
uniprot id: Q73KL9
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

243275:TDE RS03960
gene id: 243275:TDE_RS03960
uniprot id: Q73PI0
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS12200
gene id: 243275:TDE_RS12200
uniprot id: Q73K28
names: Similarity
messages: Belongs to the peptidase M18 family.

243275:TDE RS07815
gene id: 243275:TDE_RS07815
uniprot id: Q73M76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

243275:TDE RS04865
gene id: 243275:TDE_RS04865
uniprot id: Q73NY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

243275:TDE RS12110
gene id: 243275:TDE_RS12110
uniprot id: Q73K19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

243275:TDE RS06875
gene id: 243275:TDE_RS06875
uniprot id: Q73MS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

243275:TDE RS06590
gene id: 243275:TDE_RS06590
uniprot id: Q73MY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

243275:TDE RS04215
gene id: 243275:TDE_RS04215
uniprot id: P62221
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

243275:TDE RS08960
gene id: 243275:TDE_RS08960
uniprot id: Q73LI1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

243275:TDE RS00160
gene id: 243275:TDE_RS00160
uniprot id: Q73RQ5
names: Similarity
messages: Belongs to the Lgt family.

243275:TDE RS09020
gene id: 243275:TDE_RS09020
uniprot id: Q73LG7
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

243275:TDE RS00845
gene id: 243275:TDE_RS00845
uniprot id: Q73RB7
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

243275:TDE RS00370
gene id: 243275:TDE_RS00370
uniprot id: Q73RL5
names: Similarity
messages: Belongs to the ribF family.

243275:TDE RS04255
gene id: 243275:TDE_RS04255
uniprot id: P62239
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

243275:TDE RS10940
gene id: 243275:TDE_RS10940
uniprot id: Q73KA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

243275:TDE RS11345
gene id: 243275:TDE_RS11345
uniprot id: Q73JL4
names: Similarity
messages: Belongs to the sigma-54 factor family.

243275:TDE RS03220
gene id: 243275:TDE_RS03220
uniprot id: Q73PX8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

243275:TDE RS04925
gene id: 243275:TDE_RS04925
uniprot id: Q73NX3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

243275:TDE RS04650
gene id: 243275:TDE_RS04650
uniprot id: Q73P31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

243275:TDE RS01645
gene id: 243275:TDE_RS01645
uniprot id: Q73QV6
names: Activity Regulation
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.

243275:TDE RS01930
gene id: 243275:TDE_RS01930
uniprot id: Q73QP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

243275:TDE RS03835
gene id: 243275:TDE_RS03835
uniprot id: Q73PK7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

243275:TDE RS10405
gene id: 243275:TDE_RS10405
uniprot id: Q73KL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.
messages: Catalyzes the alpha,gamma-elimination of L-methionine to produce methanethiol, 2-oxobutanoate and ammonia; methanethiol (methyl mercaptan) is considered to be one of the main causes of the oral malodor associated with periodontitis and may also play a role in the pathogenicity of T.denticola. Also displays homocysteine desulfhydrase activity, degrading homocysteine to produce hydrogen sulfide, 2-oxobutanoate and ammonia.
messages: Homotetramer; dimer of active dimers.

243275:TDE RS09365
gene id: 243275:TDE_RS09365
uniprot id: Q73L92
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS04755
gene id: 243275:TDE_RS04755
uniprot id: Q73P09
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

243275:TDE RS12000
gene id: 243275:TDE_RS12000
uniprot id: Q73JZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

243275:TDE RS03800
gene id: 243275:TDE_RS03800
uniprot id: Q73PL4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

243275:TDE RS09075
gene id: 243275:TDE_RS09075
uniprot id: Q73LF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

243275:TDE RS11325
gene id: 243275:TDE_RS11325
uniprot id: Q73JL8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

243275:TDE RS04990
gene id: 243275:TDE_RS04990
uniprot id: Q73NV9
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS10890
gene id: 243275:TDE_RS10890
uniprot id: Q73KB2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

243275:TDE RS01790
gene id: 243275:TDE_RS01790
uniprot id: Q73QS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

243275:TDE RS05350
gene id: 243275:TDE_RS05350
uniprot id: Q73NN4
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

243275:TDE RS12245
gene id: 243275:TDE_RS12245
uniprot id: Q73JH6
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

243275:TDE RS07015
gene id: 243275:TDE_RS07015
uniprot id: Q73MP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

243275:TDE RS12645
gene id: 243275:TDE_RS12645
uniprot id: Q73J90
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

243275:TDE RS05760
gene id: 243275:TDE_RS05760
uniprot id: Q73NF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

243275:TDE RS00870
gene id: 243275:TDE_RS00870
uniprot id: Q73RB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

243275:TDE RS09010
gene id: 243275:TDE_RS09010
uniprot id: Q73LG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

243275:TDE RS03995
gene id: 243275:TDE_RS03995
uniprot id: Q73PH0
names: Similarity
messages: Belongs to the peptidase M18 family.

243275:TDE RS11355
gene id: 243275:TDE_RS11355
uniprot id: Q73JL2
names: Similarity
messages: Belongs to the peptidase U62 family.

243275:TDE RS11075
gene id: 243275:TDE_RS11075
uniprot id: P61310
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

243275:TDE RS00345
gene id: 243275:TDE_RS00345
uniprot id: Q73RM0
names: Similarity
messages: Belongs to the peptidase M20A family.

243275:TDE RS12235
gene id: 243275:TDE_RS12235
uniprot id: Q73JH8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

243275:TDE RS01705
gene id: 243275:TDE_RS01705
uniprot id: Q73QU4
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

243275:TDE RS09370
gene id: 243275:TDE_RS09370
uniprot id: Q73L91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

243275:TDE RS02270
gene id: 243275:TDE_RS02270
uniprot id: Q73QH3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

243275:TDE RS00910
gene id: 243275:TDE_RS00910
uniprot id: Q73RA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

243275:TDE RS00055
gene id: 243275:TDE_RS00055
uniprot id: Q73RS5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

243275:TDE RS01150
gene id: 243275:TDE_RS01150
uniprot id: Q73R57
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS05145
gene id: 243275:TDE_RS05145
uniprot id: Q73NS5
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS02935
gene id: 243275:TDE_RS02935
uniprot id: Q73Q38
names: Similarity
messages: Belongs to the ParB family.

243275:TDE RS06280
gene id: 243275:TDE_RS06280
uniprot id: Q73N45
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS01720
gene id: 243275:TDE_RS01720
uniprot id: Q73QU1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

243275:TDE RS01525
gene id: 243275:TDE_RS01525
uniprot id: Q73QY1
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS02915
gene id: 243275:TDE_RS02915
uniprot id: Q73Q42
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

243275:TDE RS09775
gene id: 243275:TDE_RS09775
uniprot id: Q73L03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

243275:TDE RS03355
gene id: 243275:TDE_RS03355
uniprot id: Q73PV1
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS06170
gene id: 243275:TDE_RS06170
uniprot id: Q73N68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

243275:TDE RS05320
gene id: 243275:TDE_RS05320
uniprot id: Q73NP0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

243275:TDE RS01475
gene id: 243275:TDE_RS01475
uniprot id: Q73QZ1
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

243275:TDE RS11435
gene id: 243275:TDE_RS11435
uniprot id: Q73JJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

243275:TDE RS01665
gene id: 243275:TDE_RS01665
uniprot id: Q73QV2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

243275:TDE RS07280
gene id: 243275:TDE_RS07280
uniprot id: Q73MI8
names: Similarity
messages: Belongs to the class-I fumarase family.

243275:TDE RS04330
gene id: 243275:TDE_RS04330
uniprot id: Q73PA3
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS07285
gene id: 243275:TDE_RS07285
uniprot id: Q73MI7
names: Similarity
messages: Belongs to the class-I fumarase family.

243275:TDE RS07120
gene id: 243275:TDE_RS07120
uniprot id: Q73MM0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

243275:TDE RS03295
gene id: 243275:TDE_RS03295
uniprot id: Q73PW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

243275:TDE RS05815
gene id: 243275:TDE_RS05815
uniprot id: Q73NE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

243275:TDE RS06520
gene id: 243275:TDE_RS06520
uniprot id: Q73MZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

243275:TDE RS05855
gene id: 243275:TDE_RS05855
uniprot id: Q73ND6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

243275:TDE RS03775
gene id: 243275:TDE_RS03775
uniprot id: Q73PL9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

243275:TDE RS07655
gene id: 243275:TDE_RS07655
uniprot id: Q73MB0
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS01780
gene id: 243275:TDE_RS01780
uniprot id: Q73QS9
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS07615
gene id: 243275:TDE_RS07615
uniprot id: Q73MB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

243275:TDE RS02780
gene id: 243275:TDE_RS02780
uniprot id: Q73Q68
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

243275:TDE RS09870
gene id: 243275:TDE_RS09870
uniprot id: Q73KY4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

243275:TDE RS12520
gene id: 243275:TDE_RS12520
uniprot id: Q73JB8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

243275:TDE RS11255
gene id: 243275:TDE_RS11255
uniprot id: Q73K39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.

243275:TDE RS00010
gene id: 243275:TDE_RS00010
uniprot id: O87546
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity).

243275:TDE RS11425
gene id: 243275:TDE_RS11425
uniprot id: Q73JJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

243275:TDE RS07215
gene id: 243275:TDE_RS07215
uniprot id: Q73MK2
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

243275:TDE RS01660
gene id: 243275:TDE_RS01660
uniprot id: Q73QV3
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

243275:TDE RS03410
gene id: 243275:TDE_RS03410
uniprot id: Q73PU0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

243275:TDE RS03360
gene id: 243275:TDE_RS03360
uniprot id: Q73PV0
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS00625
gene id: 243275:TDE_RS00625
uniprot id: Q73RG3
names: Activity Regulation
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically regulated by a feedback inhibition loop.
messages: Catalyzes the conversion of GTP to cyclic-di-GMP (c-di-GMP). Shows activity under aerobic and anaerobic reaction conditions.
messages: Cytoplasm
messages: Exists as a homodimer and as larger aggregates. Both dimers and aggregates possess DGC activity.
messages: Shows higher activity with Mn(2+) than Mg(2+).

243275:TDE RS10740
gene id: 243275:TDE_RS10740
uniprot id: Q73KE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

243275:TDE RS06895
gene id: 243275:TDE_RS06895
uniprot id: Q73MR7
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

243275:TDE RS07875
gene id: 243275:TDE_RS07875
uniprot id: Q73M64
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

243275:TDE RS04270
gene id: 243275:TDE_RS04270
uniprot id: Q73PB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

243275:TDE RS03485
gene id: 243275:TDE_RS03485
uniprot id: Q73PS7
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS04155
gene id: 243275:TDE_RS04155
uniprot id: Q73PD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

243275:TDE RS02265
gene id: 243275:TDE_RS02265
uniprot id: Q73QH4
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS03725
gene id: 243275:TDE_RS03725
uniprot id: Q73PM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

243275:TDE RS08185
gene id: 243275:TDE_RS08185
uniprot id: Q73M02
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

243275:TDE RS11180
gene id: 243275:TDE_RS11180
uniprot id: Q73K56
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS06325
gene id: 243275:TDE_RS06325
uniprot id: Q73N35
names: Similarity
messages: Belongs to the IMPACT family.

243275:TDE RS08175
gene id: 243275:TDE_RS08175
uniprot id: P61037
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane

243275:TDE RS04100
gene id: 243275:TDE_RS04100
uniprot id: Q73PE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

243275:TDE RS09670
gene id: 243275:TDE_RS09670
uniprot id: Q73L24
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS09710
gene id: 243275:TDE_RS09710
uniprot id: Q73L17
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

243275:TDE RS05835
gene id: 243275:TDE_RS05835
uniprot id: Q73NE0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane

243275:TDE RS10595
gene id: 243275:TDE_RS10595
uniprot id: Q73KH5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

243275:TDE RS01765
gene id: 243275:TDE_RS01765
uniprot id: Q73QT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

243275:TDE RS09085
gene id: 243275:TDE_RS09085
uniprot id: P61538
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

243275:TDE RS05780
gene id: 243275:TDE_RS05780
uniprot id: Q73NE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

243275:TDE RS04585
gene id: 243275:TDE_RS04585
uniprot id: Q73P44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

243275:TDE RS03080
gene id: 243275:TDE_RS03080
uniprot id: Q73Q04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

243275:TDE RS00275
gene id: 243275:TDE_RS00275
uniprot id: Q3V8B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

243275:TDE RS07175
gene id: 243275:TDE_RS07175
uniprot id: Q73MK9
names: Function
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

243275:TDE RS02315
gene id: 243275:TDE_RS02315
uniprot id: Q73QG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

243275:TDE RS00285
gene id: 243275:TDE_RS00285
uniprot id: Q73RN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

243275:TDE RS10660
gene id: 243275:TDE_RS10660
uniprot id: Q73KG1
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

243275:TDE RS00430
gene id: 243275:TDE_RS00430
uniprot id: Q73RK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

243275:TDE RS03610
gene id: 243275:TDE_RS03610
uniprot id: Q73PQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GrdA family.
messages: In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine. By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state. Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination (By similarity).
messages: Monomer. Component of the glycine, sarcosine and betaine reductase complexes, together with components B and C (By similarity).

243275:TDE RS09275
gene id: 243275:TDE_RS09275
uniprot id: Q73LB1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

243275:TDE RS06935
gene id: 243275:TDE_RS06935
uniprot id: Q73MR0
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

243275:TDE RS07870
gene id: 243275:TDE_RS07870
uniprot id: Q73M65
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

243275:TDE RS05940
gene id: 243275:TDE_RS05940
uniprot id: Q73NB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

243275:TDE RS09680
gene id: 243275:TDE_RS09680
uniprot id: Q73L22
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS12280
gene id: 243275:TDE_RS12280
uniprot id: Q73JG9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243275:TDE RS10040
gene id: 243275:TDE_RS10040
uniprot id: Q73KU8
names: Similarity
messages: Belongs to the GrdB/GrdF/GrdH family.

243275:TDE RS03050
gene id: 243275:TDE_RS03050
uniprot id: Q73Q10
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS04345
gene id: 243275:TDE_RS04345
uniprot id: Q73PA0
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS03825
gene id: 243275:TDE_RS03825
uniprot id: Q73PK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

243275:TDE RS11110
gene id: 243275:TDE_RS11110
uniprot id: Q73K70
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

243275:TDE RS01840
gene id: 243275:TDE_RS01840
uniprot id: Q73QR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

243275:TDE RS05230
gene id: 243275:TDE_RS05230
uniprot id: Q73NQ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

243275:TDE RS13335
gene id: 243275:TDE_RS13335
uniprot id: Q73RD2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

243275:TDE RS09025
gene id: 243275:TDE_RS09025
uniprot id: Q73LG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

243275:TDE RS00825
gene id: 243275:TDE_RS00825
uniprot id: Q73RC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

243275:TDE RS03930
gene id: 243275:TDE_RS03930
uniprot id: Q73PI6
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS01260
gene id: 243275:TDE_RS01260
uniprot id: Q73R36
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS05015
gene id: 243275:TDE_RS05015
uniprot id: Q73NV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

243275:TDE RS04975
gene id: 243275:TDE_RS04975
uniprot id: Q73NW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

243275:TDE RS10070
gene id: 243275:TDE_RS10070
uniprot id: Q73KU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

243275:TDE RS00295
gene id: 243275:TDE_RS00295
uniprot id: Q73RN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

243275:TDE RS10635
gene id: 243275:TDE_RS10635
uniprot id: Q73KG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

243275:TDE RS09145
gene id: 243275:TDE_RS09145
uniprot id: Q73LD8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

243275:TDE RS02965
gene id: 243275:TDE_RS02965
uniprot id: Q73Q30
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

243275:TDE RS07470
gene id: 243275:TDE_RS07470
uniprot id: Q73MF0
names: Subcellular Location Annotation
messages: Secreted

243275:TDE RS12315
gene id: 243275:TDE_RS12315
uniprot id: Q73JG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

243275:TDE RS10725
gene id: 243275:TDE_RS10725
uniprot id: Q73KE7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

243275:TDE RS10775
gene id: 243275:TDE_RS10775
uniprot id: Q73KD5
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS11530
gene id: 243275:TDE_RS11530
uniprot id: Q73JP3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

243275:TDE RS09210
gene id: 243275:TDE_RS09210
uniprot id: Q73LC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

243275:TDE RS09730
gene id: 243275:TDE_RS09730
uniprot id: Q73L14
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

243275:TDE RS12120
gene id: 243275:TDE_RS12120
uniprot id: Q73K17
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

243275:TDE RS03830
gene id: 243275:TDE_RS03830
uniprot id: Q73PK8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

243275:TDE RS11045
gene id: 243275:TDE_RS11045
uniprot id: Q73K81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

243275:TDE RS05185
gene id: 243275:TDE_RS05185
uniprot id: Q73NR7
names: Subcellular Location Annotation
messages: Cytoplasm

243275:TDE RS05765
gene id: 243275:TDE_RS05765
uniprot id: Q73NF2
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS05180
gene id: 243275:TDE_RS05180
uniprot id: Q73NR8
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

243275:TDE RS00110
gene id: 243275:TDE_RS00110
uniprot id: Q73RR4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

243275:TDE RS07940
gene id: 243275:TDE_RS07940
uniprot id: P61708
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity).
messages: Consists of two domains; the N-terminal catalytic domain (in this organism this is shorter than usual) and the editing domain; the C-terminal C-Ala domain found in most orthologs is missing. The editing domain removes incorrectly charged amino acids (By similarity).
messages: Cytoplasm

243275:TDE RS01390
gene id: 243275:TDE_RS01390
uniprot id: Q73R10
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS01075
gene id: 243275:TDE_RS01075
uniprot id: Q73R74
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

243275:TDE RS07775
gene id: 243275:TDE_RS07775
uniprot id: Q73M83
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

243275:TDE RS11970
gene id: 243275:TDE_RS11970
uniprot id: Q73JX4
names: Similarity
messages: Belongs to the MEMO1 family.

243275:TDE RS10875
gene id: 243275:TDE_RS10875
uniprot id: Q73KB6
names: Similarity
messages: Belongs to the UPF0102 family.

243275:TDE RS10060
gene id: 243275:TDE_RS10060
uniprot id: Q73KU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

243275:TDE RS04185
gene id: 243275:TDE_RS04185
uniprot id: Q73PD4
names: Subcellular Location Annotation
messages: Nucleus

243275:TDE RS04335
gene id: 243275:TDE_RS04335
uniprot id: Q73PA2
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS03765
gene id: 243275:TDE_RS03765
uniprot id: Q73PM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

243275:TDE RS07185
gene id: 243275:TDE_RS07185
uniprot id: Q73MK7
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

243275:TDE RS04985
gene id: 243275:TDE_RS04985
uniprot id: P61912
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

243275:TDE RS06510
gene id: 243275:TDE_RS06510
uniprot id: Q73MZ9
names: Similarity
messages: Belongs to the aldose epimerase family.

243275:TDE RS04070
gene id: 243275:TDE_RS04070
uniprot id: Q73PF5
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

243275:TDE RS11280
gene id: 243275:TDE_RS11280
uniprot id: Q73JM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

243275:TDE RS04820
gene id: 243275:TDE_RS04820
uniprot id: Q73NZ3
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

243275:TDE RS04495
gene id: 243275:TDE_RS04495
uniprot id: Q73P65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

243275:TDE RS07805
gene id: 243275:TDE_RS07805
uniprot id: Q73M78
names: Subcellular Location Annotation
messages: Cytoplasm

243275:TDE RS00380
gene id: 243275:TDE_RS00380
uniprot id: Q73RL3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

243275:TDE RS04790
gene id: 243275:TDE_RS04790
uniprot id: Q73P01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

243275:TDE RS04465
gene id: 243275:TDE_RS04465
uniprot id: Q73P71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PhnC), two transmembrane proteins (PhnE) and a solute-binding protein (PhnD).

243275:TDE RS11945
gene id: 243275:TDE_RS11945
uniprot id: Q73JX9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

243275:TDE RS08500
gene id: 243275:TDE_RS08500
uniprot id: Q73LT8
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

243275:TDE RS00150
gene id: 243275:TDE_RS00150
uniprot id: Q73RQ7
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS02975
gene id: 243275:TDE_RS02975
uniprot id: Q73Q25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

243275:TDE RS04910
gene id: 243275:TDE_RS04910
uniprot id: Q73NX7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

243275:TDE RS00890
gene id: 243275:TDE_RS00890
uniprot id: Q73RA6
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS03855
gene id: 243275:TDE_RS03855
uniprot id: Q73PK3
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

243275:TDE RS06470
gene id: 243275:TDE_RS06470
uniprot id: Q73N06
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

243275:TDE RS06065
gene id: 243275:TDE_RS06065
uniprot id: Q73N90
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

243275:TDE RS11940
gene id: 243275:TDE_RS11940
uniprot id: Q73JY0
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS12695
gene id: 243275:TDE_RS12695
uniprot id: Q73J79
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS04575
gene id: 243275:TDE_RS04575
uniprot id: Q73P46
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS04470
gene id: 243275:TDE_RS04470
uniprot id: Q73P70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

243275:TDE RS06190
gene id: 243275:TDE_RS06190
uniprot id: Q73N63
names: Similarity
messages: Belongs to the peptidase U62 family.

243275:TDE RS04945
gene id: 243275:TDE_RS04945
uniprot id: Q73NW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

243275:TDE RS00610
gene id: 243275:TDE_RS00610
uniprot id: Q73RG6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

243275:TDE RS09055
gene id: 243275:TDE_RS09055
uniprot id: Q73LF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

243275:TDE RS01710
gene id: 243275:TDE_RS01710
uniprot id: Q73QU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

243275:TDE RS06900
gene id: 243275:TDE_RS06900
uniprot id: Q73MR6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

243275:TDE RS03820
gene id: 243275:TDE_RS03820
uniprot id: Q73PL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

243275:TDE RS07290
gene id: 243275:TDE_RS07290
uniprot id: Q73MI6
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

243275:TDE RS11320
gene id: 243275:TDE_RS11320
uniprot id: Q73JL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

243275:TDE RS01430
gene id: 243275:TDE_RS01430
uniprot id: Q73R01
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

243275:TDE RS04025
gene id: 243275:TDE_RS04025
uniprot id: Q73PG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

243275:TDE RS05775
gene id: 243275:TDE_RS05775
uniprot id: Q73NF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

243275:TDE RS01595
gene id: 243275:TDE_RS01595
uniprot id: Q73QW7
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

243275:TDE RS05875
gene id: 243275:TDE_RS05875
uniprot id: Q73ND2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

243275:TDE RS03710
gene id: 243275:TDE_RS03710
uniprot id: Q73PN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

243275:TDE RS05370
gene id: 243275:TDE_RS05370
uniprot id: Q73NN0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

243275:TDE RS04460
gene id: 243275:TDE_RS04460
uniprot id: Q73P72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

243275:TDE RS04580
gene id: 243275:TDE_RS04580
uniprot id: Q73P45
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS06370
gene id: 243275:TDE_RS06370
uniprot id: Q73N24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

243275:TDE RS01200
gene id: 243275:TDE_RS01200
uniprot id: Q73R47
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS12940
gene id: 243275:TDE_RS12940
uniprot id: Q73J26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

243275:TDE RS05300
gene id: 243275:TDE_RS05300
uniprot id: Q73NP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

243275:TDE RS05235
gene id: 243275:TDE_RS05235
uniprot id: Q73NQ7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

243275:TDE RS03235
gene id: 243275:TDE_RS03235
uniprot id: Q73PX5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

243275:TDE RS04250
gene id: 243275:TDE_RS04250
uniprot id: Q73PB9
names: Similarity
messages: Belongs to the CobT family.

243275:TDE RS03275
gene id: 243275:TDE_RS03275
uniprot id: Q73PW8
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

243275:TDE RS03605
gene id: 243275:TDE_RS03605
uniprot id: Q73PQ3
names: Similarity
messages: Belongs to the thioredoxin family.

243275:TDE RS06790
gene id: 243275:TDE_RS06790
uniprot id: Q73MU0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

243275:TDE RS07535
gene id: 243275:TDE_RS07535
uniprot id: Q73MD5
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

243275:TDE RS13010
gene id: 243275:TDE_RS13010
uniprot id: F7IU92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

243275:TDE RS08360
gene id: 243275:TDE_RS08360
uniprot id: Q73LW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

243275:TDE RS12030
gene id: 243275:TDE_RS12030
uniprot id: Q73K10
names: Similarity
messages: Belongs to the CobH/CbiC family.

243275:TDE RS02860
gene id: 243275:TDE_RS02860
uniprot id: Q73Q54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

243275:TDE RS02190
gene id: 243275:TDE_RS02190
uniprot id: Q73QJ1
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

243275:TDE RS00155
gene id: 243275:TDE_RS00155
uniprot id: Q73RQ6
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS03040
gene id: 243275:TDE_RS03040
uniprot id: Q73Q12
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

243275:TDE RS00640
gene id: 243275:TDE_RS00640
uniprot id: Q73RG0
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS04980
gene id: 243275:TDE_RS04980
uniprot id: Q73NW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

243275:TDE RS06070
gene id: 243275:TDE_RS06070
uniprot id: Q73N89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

243275:TDE RS09830
gene id: 243275:TDE_RS09830
uniprot id: Q73KZ3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

243275:TDE RS02890
gene id: 243275:TDE_RS02890
uniprot id: Q73Q47
names: Activity Regulation
names: Biotechnology
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Inhibited by lauroyl-CoA.
messages: Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of the carbon-carbon double bond of crotonyl-CoA to yield butyryl-CoA. In vitro it can also use hexenoyl-CoA and dodecenoyl-CoA as substrates (PubMed:22906002).
messages: Monomer.
messages: Possesses high activity for the reduction reaction, but no activity for the reverse oxidation reaction.
messages: Used in the biosynthesis of medium-chain volatile alcohols as biofuels engineered by microorganisms. The switch from the native flavin-dependent enoyl-CoA reductase used in the production of n-butanol, a key second-generation biofuel, to a flavin-independent trans-enoyl-CoA reductase from T.denticola leads to an order of magnitude increase in product yield in engineered E.coli.

243275:TDE RS04475
gene id: 243275:TDE_RS04475
uniprot id: Q73P69
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

243275:TDE RS10360
gene id: 243275:TDE_RS10360
uniprot id: Q73KM7
names: Similarity
messages: Belongs to the RecJ family.

243275:TDE RS06270
gene id: 243275:TDE_RS06270
uniprot id: Q73N47
names: Similarity
messages: Belongs to the peptidase U62 family.

243275:TDE RS07360
gene id: 243275:TDE_RS07360
uniprot id: Q73MH0
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

243275:TDE RS11845
gene id: 243275:TDE_RS11845
uniprot id: Q73JU9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

243275:TDE RS06375
gene id: 243275:TDE_RS06375
uniprot id: Q73N23
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

243275:TDE RS05515
gene id: 243275:TDE_RS05515
uniprot id: Q73NK0
names: Subcellular Location Annotation
messages: Virion

243275:TDE RS00200
gene id: 243275:TDE_RS00200
uniprot id: Q73RP7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

243275:TDE RS04900
gene id: 243275:TDE_RS04900
uniprot id: P61191
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

243275:TDE RS11235
gene id: 243275:TDE_RS11235
uniprot id: Q73K43
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS01400
gene id: 243275:TDE_RS01400
uniprot id: Q73R08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

243275:TDE RS12070
gene id: 243275:TDE_RS12070
uniprot id: Q73K01
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

243275:TDE RS00725
gene id: 243275:TDE_RS00725
uniprot id: Q73RD9
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS11450
gene id: 243275:TDE_RS11450
uniprot id: Q73JJ2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

243275:TDE RS10475
gene id: 243275:TDE_RS10475
uniprot id: Q73KK3
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS03795
gene id: 243275:TDE_RS03795
uniprot id: Q73PL5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

243275:TDE RS02120
gene id: 243275:TDE_RS02120
uniprot id: Q73QK5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

243275:TDE RS12320
gene id: 243275:TDE_RS12320
uniprot id: Q73JG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

243275:TDE RS11125
gene id: 243275:TDE_RS11125
uniprot id: Q73K67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

243275:TDE RS02060
gene id: 243275:TDE_RS02060
uniprot id: Q73QL8
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS05195
gene id: 243275:TDE_RS05195
uniprot id: Q73NR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

243275:TDE RS03290
gene id: 243275:TDE_RS03290
uniprot id: Q73PW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

243275:TDE RS04450
gene id: 243275:TDE_RS04450
uniprot id: Q73P74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

243275:TDE RS05830
gene id: 243275:TDE_RS05830
uniprot id: O06679
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

243275:TDE RS06415
gene id: 243275:TDE_RS06415
uniprot id: Q73N16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

243275:TDE RS11650
gene id: 243275:TDE_RS11650
uniprot id: Q73JR5
names: Similarity
messages: Belongs to the hexokinase family.

243275:TDE RS05810
gene id: 243275:TDE_RS05810
uniprot id: P61478
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

243275:TDE RS10990
gene id: 243275:TDE_RS10990
uniprot id: Q73K92
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent (By similarity).
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
messages: The Clp repeat (R) domain probably functions as a substrate-discriminating domain, recruiting aggregated proteins to the ClpB hexamer and/or stabilizing bound proteins. The NBD2 domain is responsible for oligomerization, whereas the NBD1 domain stabilizes the hexamer probably in an ATP-dependent manner. The movement of the coiled-coil domain is essential for ClpB ability to rescue proteins from an aggregated state, probably by pulling apart large aggregated proteins, which are bound between the coiled-coils motifs of adjacent ClpB subunits in the functional hexamer (By similarity).

243275:TDE RS07010
gene id: 243275:TDE_RS07010
uniprot id: Q73MP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

243275:TDE RS00015
gene id: 243275:TDE_RS00015
uniprot id: O87545
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

243275:TDE RS07675
gene id: 243275:TDE_RS07675
uniprot id: Q73MA5
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS06930
gene id: 243275:TDE_RS06930
uniprot id: Q73MR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

243275:TDE RS06705
gene id: 243275:TDE_RS06705
uniprot id: Q73MV7
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: In the C-terminal section; belongs to the NAD synthetase family.

243275:TDE RS02455
gene id: 243275:TDE_RS02455
uniprot id: Q73QD7
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

243275:TDE RS00065
gene id: 243275:TDE_RS00065
uniprot id: Q73RS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

243275:TDE RS06570
gene id: 243275:TDE_RS06570
uniprot id: Q73MY6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243275:TDE RS01540
gene id: 243275:TDE_RS01540
uniprot id: Q73QX8
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS03860
gene id: 243275:TDE_RS03860
uniprot id: Q73PK2
names: Similarity
messages: Belongs to the acylphosphatase family.

243275:TDE RS00620
gene id: 243275:TDE_RS00620
uniprot id: Q73RG4
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS12100
gene id: 243275:TDE_RS12100
uniprot id: Q73K21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

243275:TDE RS01825
gene id: 243275:TDE_RS01825
uniprot id: Q73QS0
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS08375
gene id: 243275:TDE_RS08375
uniprot id: Q73LW5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

243275:TDE RS06240
gene id: 243275:TDE_RS06240
uniprot id: Q73N54
names: Similarity
messages: Belongs to the hemerythrin family.

243275:TDE RS09345
gene id: 243275:TDE_RS09345
uniprot id: Q73L97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

243275:TDE RS08830
gene id: 243275:TDE_RS08830
uniprot id: Q73LL2
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS09990
gene id: 243275:TDE_RS09990
uniprot id: Q73KV8
names: Similarity
messages: Belongs to the DEAD box helicase family.

243275:TDE RS05930
gene id: 243275:TDE_RS05930
uniprot id: Q73NB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

243275:TDE RS02855
gene id: 243275:TDE_RS02855
uniprot id: Q73Q55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

243275:TDE RS09470
gene id: 243275:TDE_RS09470
uniprot id: Q73L67
names: Similarity
messages: Belongs to the phosphohexose mutase family.

243275:TDE RS06400
gene id: 243275:TDE_RS06400
uniprot id: Q73N18
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

243275:TDE RS12370
gene id: 243275:TDE_RS12370
uniprot id: Q73JF0
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS06955
gene id: 243275:TDE_RS06955
uniprot id: Q73MQ5
names: Similarity
messages: Belongs to the glycosyl hydrolase.

243275:TDE RS12685
gene id: 243275:TDE_RS12685
uniprot id: Q73J81
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

243275:TDE RS10365
gene id: 243275:TDE_RS10365
uniprot id: Q73KM6
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

243275:TDE RS07035
gene id: 243275:TDE_RS07035
uniprot id: Q73MN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

243275:TDE RS00045
gene id: 243275:TDE_RS00045
uniprot id: Q73RS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

243275:TDE RS09165
gene id: 243275:TDE_RS09165
uniprot id: Q73LD4
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

243275:TDE RS02235
gene id: 243275:TDE_RS02235
uniprot id: Q73QI0
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

243275:TDE RS00980
gene id: 243275:TDE_RS00980
uniprot id: Q73R87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

243275:TDE RS03175
gene id: 243275:TDE_RS03175
uniprot id: Q73PY7
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS07610
gene id: 243275:TDE_RS07610
uniprot id: Q73MB9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

243275:TDE RS10555
gene id: 243275:TDE_RS10555
uniprot id: Q73KI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

243275:TDE RS10095
gene id: 243275:TDE_RS10095
uniprot id: Q73KT6
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS04920
gene id: 243275:TDE_RS04920
uniprot id: Q73NX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

243275:TDE RS07250
gene id: 243275:TDE_RS07250
uniprot id: Q73MJ4
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS05075
gene id: 243275:TDE_RS05075
uniprot id: Q73NT9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

243275:TDE RS05280
gene id: 243275:TDE_RS05280
uniprot id: Q73NP8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

243275:TDE RS01495
gene id: 243275:TDE_RS01495
uniprot id: Q73QY7
names: Similarity
messages: Belongs to the peptidase S49 family.

243275:TDE RS03985
gene id: 243275:TDE_RS03985
uniprot id: Q73PH3
names: Similarity
messages: Belongs to the UPF0339 family.

243275:TDE RS07060
gene id: 243275:TDE_RS07060
uniprot id: Q73MN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

243275:TDE RS11820
gene id: 243275:TDE_RS11820
uniprot id: Q73JV5
names: Cofactor
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

243275:TDE RS09510
gene id: 243275:TDE_RS09510
uniprot id: Q73L58
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS03330
gene id: 243275:TDE_RS03330
uniprot id: Q73PV7
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Homodimer.

243275:TDE RS01340
gene id: 243275:TDE_RS01340
uniprot id: Q73R20
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS10310
gene id: 243275:TDE_RS10310
uniprot id: Q73KN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

243275:TDE RS04175
gene id: 243275:TDE_RS04175
uniprot id: Q73PD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

243275:TDE RS04435
gene id: 243275:TDE_RS04435
uniprot id: Q73P77
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS06440
gene id: 243275:TDE_RS06440
uniprot id: Q73N11
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

243275:TDE RS11855
gene id: 243275:TDE_RS11855
uniprot id: Q73JU7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

243275:TDE RS11655
gene id: 243275:TDE_RS11655
uniprot id: Q73JR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

243275:TDE RS12045
gene id: 243275:TDE_RS12045
uniprot id: Q73K06
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS12340
gene id: 243275:TDE_RS12340
uniprot id: Q73JF6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

243275:TDE RS00070
gene id: 243275:TDE_RS00070
uniprot id: Q73RS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

243275:TDE RS01205
gene id: 243275:TDE_RS01205
uniprot id: Q73R46
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS02870
gene id: 243275:TDE_RS02870
uniprot id: Q73Q52
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

243275:TDE RS05290
gene id: 243275:TDE_RS05290
uniprot id: Q73NP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

243275:TDE RS11850
gene id: 243275:TDE_RS11850
uniprot id: Q73JU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

243275:TDE RS11115
gene id: 243275:TDE_RS11115
uniprot id: Q73K69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasmic flagellum

243275:TDE RS07200
gene id: 243275:TDE_RS07200
uniprot id: Q73MK5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243275:TDE RS11865
gene id: 243275:TDE_RS11865
uniprot id: Q73JX0
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

243275:TDE RS12020
gene id: 243275:TDE_RS12020
uniprot id: Q73JY6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243275:TDE RS03790
gene id: 243275:TDE_RS03790
uniprot id: Q73PL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

243275:TDE RS08280
gene id: 243275:TDE_RS08280
uniprot id: Q73LY3
names: Similarity
messages: Belongs to the glutathione peroxidase family.

243275:TDE RS00105
gene id: 243275:TDE_RS00105
uniprot id: Q73RR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

243275:TDE RS10255
gene id: 243275:TDE_RS10255
uniprot id: Q73KQ1
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

243275:TDE RS05240
gene id: 243275:TDE_RS05240
uniprot id: Q73NQ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

243275:TDE RS06540
gene id: 243275:TDE_RS06540
uniprot id: Q73MZ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

243275:TDE RS06265
gene id: 243275:TDE_RS06265
uniprot id: Q73N48
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

243275:TDE RS09620
gene id: 243275:TDE_RS09620
uniprot id: Q73L35
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

243275:TDE RS12840
gene id: 243275:TDE_RS12840
uniprot id: Q73J47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

243275:TDE RS06040
gene id: 243275:TDE_RS06040
uniprot id: Q73N96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

243275:TDE RS12295
gene id: 243275:TDE_RS12295
uniprot id: Q73JG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

243275:TDE RS05020
gene id: 243275:TDE_RS05020
uniprot id: Q73NV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

243275:TDE RS09505
gene id: 243275:TDE_RS09505
uniprot id: Q73L59
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS08305
gene id: 243275:TDE_RS08305
uniprot id: Q73LX8
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

243275:TDE RS07220
gene id: 243275:TDE_RS07220
uniprot id: Q73MK1
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

243275:TDE RS07600
gene id: 243275:TDE_RS07600
uniprot id: Q73MC1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

243275:TDE RS08930
gene id: 243275:TDE_RS08930
uniprot id: Q73LI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

243275:TDE RS09000
gene id: 243275:TDE_RS09000
uniprot id: P60794
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

243275:TDE RS01465
gene id: 243275:TDE_RS01465
uniprot id: Q73QZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

243275:TDE RS07855
gene id: 243275:TDE_RS07855
uniprot id: Q73M68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

243275:TDE RS08330
gene id: 243275:TDE_RS08330
uniprot id: Q73LX3
names: Similarity
messages: Belongs to the FemABX family.

243275:TDE RS11440
gene id: 243275:TDE_RS11440
uniprot id: Q73JJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

243275:TDE RS08080
gene id: 243275:TDE_RS08080
uniprot id: Q73M25
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

243275:TDE RS00850
gene id: 243275:TDE_RS00850
uniprot id: Q73RB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

243275:TDE RS03590
gene id: 243275:TDE_RS03590
uniprot id: Q73PQ9
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

243275:TDE RS05745
gene id: 243275:TDE_RS05745
uniprot id: Q73NF6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

243275:TDE RS11285
gene id: 243275:TDE_RS11285
uniprot id: Q73JM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

243275:TDE RS01760
gene id: 243275:TDE_RS01760
uniprot id: Q73QT3
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS12980
gene id: 243275:TDE_RS12980
uniprot id: Q73J18
names: Similarity
messages: Belongs to the HepT RNase toxin family.

243275:TDE RS00645
gene id: 243275:TDE_RS00645
uniprot id: Q04595
names: Similarity
messages: In the C-terminal section; belongs to the PyrI family.
messages: In the N-terminal section; belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

243275:TDE RS10795
gene id: 243275:TDE_RS10795
uniprot id: Q73KD1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

243275:TDE RS13020
gene id: 243275:TDE_RS13020
uniprot id: F7IWN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

243275:TDE RS12805
gene id: 243275:TDE_RS12805
uniprot id: Q73J56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

243275:TDE RS08410
gene id: 243275:TDE_RS08410
uniprot id: Q73LV8
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

243275:TDE RS00365
gene id: 243275:TDE_RS00365
uniprot id: Q73RL6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243275:TDE RS10640
gene id: 243275:TDE_RS10640
uniprot id: Q73KG6
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

243275:TDE RS12810
gene id: 243275:TDE_RS12810
uniprot id: Q73J55
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

243275:TDE RS12250
gene id: 243275:TDE_RS12250
uniprot id: Q73JH5
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS07975
gene id: 243275:TDE_RS07975
uniprot id: Q73M43
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

243275:TDE RS01985
gene id: 243275:TDE_RS01985
uniprot id: Q73QN5
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

243275:TDE RS06290
gene id: 243275:TDE_RS06290
uniprot id: Q73N43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

243275:TDE RS09805
gene id: 243275:TDE_RS09805
uniprot id: Q73KZ8
names: Similarity
messages: Belongs to the RutC family.

243275:TDE RS07555
gene id: 243275:TDE_RS07555
uniprot id: Q73MD1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

243275:TDE RS07765
gene id: 243275:TDE_RS07765
uniprot id: P62031
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

243275:TDE RS11175
gene id: 243275:TDE_RS11175
uniprot id: Q73K57
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS10030
gene id: 243275:TDE_RS10030
uniprot id: Q73KV0
names: Similarity
messages: Belongs to the UPF0164 family.

243275:TDE RS12390
gene id: 243275:TDE_RS12390
uniprot id: Q73JE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

243275:TDE RS01640
gene id: 243275:TDE_RS01640
uniprot id: Q73QV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

243275:TDE RS09415
gene id: 243275:TDE_RS09415
uniprot id: Q73L79
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

243275:TDE RS04805
gene id: 243275:TDE_RS04805
uniprot id: Q73NZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

243275:TDE RS00465
gene id: 243275:TDE_RS00465
uniprot id: Q73RJ7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

243275:TDE RS03405
gene id: 243275:TDE_RS03405
uniprot id: Q73PU1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

243275:TDE RS05170
gene id: 243275:TDE_RS05170
uniprot id: Q73NS0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

243275:TDE RS06830
gene id: 243275:TDE_RS06830
uniprot id: Q73MT1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

243275:TDE RS03810
gene id: 243275:TDE_RS03810
uniprot id: Q73PL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

243275:TDE RS11455
gene id: 243275:TDE_RS11455
uniprot id: Q73JJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

243275:TDE RS12090
gene id: 243275:TDE_RS12090
uniprot id: Q73K23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

243275:TDE RS07115
gene id: 243275:TDE_RS07115
uniprot id: P62042
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

243275:TDE RS07575
gene id: 243275:TDE_RS07575
uniprot id: Q73MC7
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

243275:TDE RS04260
gene id: 243275:TDE_RS04260
uniprot id: Q73PB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

243275:TDE RS07955
gene id: 243275:TDE_RS07955
uniprot id: Q73M48
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

243275:TDE RS06115
gene id: 243275:TDE_RS06115
uniprot id: Q73N80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

243275:TDE RS06320
gene id: 243275:TDE_RS06320
uniprot id: Q73N36
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS09890
gene id: 243275:TDE_RS09890
uniprot id: P61696
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

243275:TDE RS11375
gene id: 243275:TDE_RS11375
uniprot id: Q73JK7
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

243275:TDE RS03095
gene id: 243275:TDE_RS03095
uniprot id: Q73Q01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

243275:TDE RS06075
gene id: 243275:TDE_RS06075
uniprot id: Q73N88
names: Similarity
messages: Belongs to the GARS family.

243275:TDE RS10490
gene id: 243275:TDE_RS10490
uniprot id: Q73KK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

243275:TDE RS03770
gene id: 243275:TDE_RS03770
uniprot id: Q73PM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

243275:TDE RS03895
gene id: 243275:TDE_RS03895
uniprot id: Q73PJ5
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

243275:TDE RS08895
gene id: 243275:TDE_RS08895
uniprot id: Q73LJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

243275:TDE RS10140
gene id: 243275:TDE_RS10140
uniprot id: Q73KS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

243275:TDE RS10720
gene id: 243275:TDE_RS10720
uniprot id: Q73KE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

243275:TDE RS13120
gene id: 243275:TDE_RS13120
uniprot id: Q73IZ2
names: Similarity
messages: Belongs to the YggT family.

243275:TDE RS09095
gene id: 243275:TDE_RS09095
uniprot id: Q73LE9
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

243275:TDE RS11035
gene id: 243275:TDE_RS11035
uniprot id: Q73K84
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS10380
gene id: 243275:TDE_RS10380
uniprot id: Q73KM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

243275:TDE RS00470
gene id: 243275:TDE_RS00470
uniprot id: Q73RJ6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

243275:TDE RS11410
gene id: 243275:TDE_RS11410
uniprot id: Q73JK0
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS00865
gene id: 243275:TDE_RS00865
uniprot id: Q73RB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

243275:TDE RS03195
gene id: 243275:TDE_RS03195
uniprot id: Q73PY3
names: Similarity
messages: Belongs to the YoeB family.

243275:TDE RS10780
gene id: 243275:TDE_RS10780
uniprot id: Q73KD4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

243275:TDE RS11885
gene id: 243275:TDE_RS11885
uniprot id: Q73JW5
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS05105
gene id: 243275:TDE_RS05105
uniprot id: F7IVL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

243275:TDE RS04490
gene id: 243275:TDE_RS04490
uniprot id: Q73P66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

243275:TDE RS11835
gene id: 243275:TDE_RS11835
uniprot id: Q73JV1
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS11445
gene id: 243275:TDE_RS11445
uniprot id: P62443
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

243275:TDE RS09245
gene id: 243275:TDE_RS09245
uniprot id: Q73LB7
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS04940
gene id: 243275:TDE_RS04940
uniprot id: Q73NW9
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

243275:TDE RS03715
gene id: 243275:TDE_RS03715
uniprot id: P61070
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

243275:TDE RS08010
gene id: 243275:TDE_RS08010
uniprot id: Q73M38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

243275:TDE RS11950
gene id: 243275:TDE_RS11950
uniprot id: Q73JX8
names: Similarity
messages: Belongs to the pyruvate kinase family.

243275:TDE RS10235
gene id: 243275:TDE_RS10235
uniprot id: Q73KQ5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

243275:TDE RS04815
gene id: 243275:TDE_RS04815
uniprot id: Q73NZ4
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

243275:TDE RS04830
gene id: 243275:TDE_RS04830
uniprot id: Q73NZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

243275:TDE RS08025
gene id: 243275:TDE_RS08025
uniprot id: Q73M35
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

243275:TDE RS10565
gene id: 243275:TDE_RS10565
uniprot id: Q73KI3
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

243275:TDE RS09325
gene id: 243275:TDE_RS09325
uniprot id: Q73LA1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

243275:TDE RS08890
gene id: 243275:TDE_RS08890
uniprot id: Q73LJ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

243275:TDE RS06465
gene id: 243275:TDE_RS06465
uniprot id: Q73N07
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243275:TDE RS04385
gene id: 243275:TDE_RS04385
uniprot id: Q73P91
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS01130
gene id: 243275:TDE_RS01130
uniprot id: Q73R61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

243275:TDE RS01545
gene id: 243275:TDE_RS01545
uniprot id: Q73QX7
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS10440
gene id: 243275:TDE_RS10440
uniprot id: Q73KL0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

243275:TDE RS00245
gene id: 243275:TDE_RS00245
uniprot id: Q73RN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

243275:TDE RS04110
gene id: 243275:TDE_RS04110
uniprot id: Q73PE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

243275:TDE RS12095
gene id: 243275:TDE_RS12095
uniprot id: Q73K22
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

243275:TDE RS01755
gene id: 243275:TDE_RS01755
uniprot id: Q73QT4
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS02210
gene id: 243275:TDE_RS02210
uniprot id: Q73QI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

243275:TDE RS03745
gene id: 243275:TDE_RS03745
uniprot id: Q73PM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

243275:TDE RS13005
gene id: 243275:TDE_RS13005
uniprot id: F7IW30
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

243275:TDE RS00835
gene id: 243275:TDE_RS00835
uniprot id: P60941
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

243275:TDE RS05820
gene id: 243275:TDE_RS05820
uniprot id: Q73NE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

243275:TDE RS01460
gene id: 243275:TDE_RS01460
uniprot id: Q73QZ4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

243275:TDE RS00735
gene id: 243275:TDE_RS00735
uniprot id: Q73RD7
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS02895
gene id: 243275:TDE_RS02895
uniprot id: Q73Q46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

243275:TDE RS03340
gene id: 243275:TDE_RS03340
uniprot id: Q73PV5
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS06195
gene id: 243275:TDE_RS06195
uniprot id: Q73N62
names: Similarity
messages: Belongs to the peptidase U62 family.

243275:TDE RS07905
gene id: 243275:TDE_RS07905
uniprot id: Q73M57
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS05160
gene id: 243275:TDE_RS05160
uniprot id: Q73NS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

243275:TDE RS08990
gene id: 243275:TDE_RS08990
uniprot id: Q73LH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Membrane

243275:TDE RS08195
gene id: 243275:TDE_RS08195
uniprot id: Q73M00
names: Function
names: Subcellular Location Annotation
messages: Component of the outer layer of the flagella.
messages: Periplasmic flagellum

243275:TDE RS03600
gene id: 243275:TDE_RS03600
uniprot id: Q73PQ4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

243275:TDE RS10750
gene id: 243275:TDE_RS10750
uniprot id: Q73KE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

243275:TDE RS03070
gene id: 243275:TDE_RS03070
uniprot id: Q73Q06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

243275:TDE RS11135
gene id: 243275:TDE_RS11135
uniprot id: Q73K65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

243275:TDE RS05035
gene id: 243275:TDE_RS05035
uniprot id: Q73NV0
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

243275:TDE RS12375
gene id: 243275:TDE_RS12375
uniprot id: Q73JE9
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS04800
gene id: 243275:TDE_RS04800
uniprot id: Q73NZ9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243275:TDE RS12575
gene id: 243275:TDE_RS12575
uniprot id: Q73JA5
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS05190
gene id: 243275:TDE_RS05190
uniprot id: Q73NR6
names: Similarity
messages: Belongs to the YicC/YloC family.

243275:TDE RS07460
gene id: 243275:TDE_RS07460
uniprot id: Q73MF2
names: Similarity
messages: Belongs to the bacterial secretin family.

243275:TDE RS01925
gene id: 243275:TDE_RS01925
uniprot id: Q73QP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

243275:TDE RS07840
gene id: 243275:TDE_RS07840
uniprot id: Q73M71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

243275:TDE RS03385
gene id: 243275:TDE_RS03385
uniprot id: Q73PU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

243275:TDE RS00375
gene id: 243275:TDE_RS00375
uniprot id: Q73RL4
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS03990
gene id: 243275:TDE_RS03990
uniprot id: Q73PH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

243275:TDE RS01315
gene id: 243275:TDE_RS01315
uniprot id: Q73R26
names: Similarity
messages: Belongs to the HAM1 NTPase family.

243275:TDE RS03525
gene id: 243275:TDE_RS03525
uniprot id: Q73PS1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

243275:TDE RS12835
gene id: 243275:TDE_RS12835
uniprot id: Q73J49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

243275:TDE RS03760
gene id: 243275:TDE_RS03760
uniprot id: Q73PM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

243275:TDE RS10835
gene id: 243275:TDE_RS10835
uniprot id: Q73KC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

243275:TDE RS07735
gene id: 243275:TDE_RS07735
uniprot id: Q73M93
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

243275:TDE RS07430
gene id: 243275:TDE_RS07430
uniprot id: Q73MF8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

243275:TDE RS06430
gene id: 243275:TDE_RS06430
uniprot id: Q73N13
names: Similarity
messages: Belongs to the peptidase S1C family.

243275:TDE RS11090
gene id: 243275:TDE_RS11090
uniprot id: Q73K74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

243275:TDE RS05890
gene id: 243275:TDE_RS05890
uniprot id: Q73NC9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

243275:TDE RS09980
gene id: 243275:TDE_RS09980
uniprot id: Q73KW0
names: Function
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

243275:TDE RS03785
gene id: 243275:TDE_RS03785
uniprot id: Q73PL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

243275:TDE RS08265
gene id: 243275:TDE_RS08265
uniprot id: Q73LY6
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

243275:TDE RS00270
gene id: 243275:TDE_RS00270
uniprot id: Q3V8B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

243275:TDE RS03805
gene id: 243275:TDE_RS03805
uniprot id: Q73PL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

243275:TDE RS01715
gene id: 243275:TDE_RS01715
uniprot id: P62056
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

243275:TDE RS05805
gene id: 243275:TDE_RS05805
uniprot id: Q73NE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

243275:TDE RS07645
gene id: 243275:TDE_RS07645
uniprot id: Q73MB2
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS03815
gene id: 243275:TDE_RS03815
uniprot id: Q73PL1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

243275:TDE RS03670
gene id: 243275:TDE_RS03670
uniprot id: Q73PP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

243275:TDE RS08405
gene id: 243275:TDE_RS08405
uniprot id: Q73LV9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

243275:TDE RS01235
gene id: 243275:TDE_RS01235
uniprot id: Q73R41
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

243275:TDE RS10515
gene id: 243275:TDE_RS10515
uniprot id: Q73KJ3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

243275:TDE RS11640
gene id: 243275:TDE_RS11640
uniprot id: Q73JR8
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

243275:TDE RS04915
gene id: 243275:TDE_RS04915
uniprot id: Q73NX6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

243275:TDE RS12920
gene id: 243275:TDE_RS12920
uniprot id: Q73J29
names: Similarity
messages: Belongs to the HsdR family.

243275:TDE RS07235
gene id: 243275:TDE_RS07235
uniprot id: Q73MJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

243275:TDE RS04995
gene id: 243275:TDE_RS04995
uniprot id: Q73NV8
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS06050
gene id: 243275:TDE_RS06050
uniprot id: Q73N94
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS12600
gene id: 243275:TDE_RS12600
uniprot id: Q73JA0
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS11670
gene id: 243275:TDE_RS11670
uniprot id: Q73JR1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

243275:TDE RS04835
gene id: 243275:TDE_RS04835
uniprot id: Q73NZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

243275:TDE RS01385
gene id: 243275:TDE_RS01385
uniprot id: Q73R11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).

243275:TDE RS08385
gene id: 243275:TDE_RS08385
uniprot id: Q73LW3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

243275:TDE RS06485
gene id: 243275:TDE_RS06485
uniprot id: Q73N03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

243275:TDE RS12115
gene id: 243275:TDE_RS12115
uniprot id: Q73K18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

243275:TDE RS00495
gene id: 243275:TDE_RS00495
uniprot id: Q73RI9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

243275:TDE RS07065
gene id: 243275:TDE_RS07065
uniprot id: Q73MN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

243275:TDE RS10690
gene id: 243275:TDE_RS10690
uniprot id: Q73KF4
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS03320
gene id: 243275:TDE_RS03320
uniprot id: Q73PV9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class II subfamily.
messages: Catalyzes the reversible conversion of 5-aminoimidazole ribonucleotide (AIR) and CO(2) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). Does not accept N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) as a substrate.

243275:TDE RS00885
gene id: 243275:TDE_RS00885
uniprot id: Q73RA7
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS03940
gene id: 243275:TDE_RS03940
uniprot id: Q73PI4
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS01565
gene id: 243275:TDE_RS01565
uniprot id: Q73QX3
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS01020
gene id: 243275:TDE_RS01020
uniprot id: Q73R80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

243275:TDE RS01695
gene id: 243275:TDE_RS01695
uniprot id: F7IV85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

243275:TDE RS11565
gene id: 243275:TDE_RS11565
uniprot id: Q73JN5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

243275:TDE RS05305
gene id: 243275:TDE_RS05305
uniprot id: Q73NP3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

243275:TDE RS11475
gene id: 243275:TDE_RS11475
uniprot id: Q73JI9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

243275:TDE RS04440
gene id: 243275:TDE_RS04440
uniprot id: Q73P76
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS05285
gene id: 243275:TDE_RS05285
uniprot id: Q73NP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

243275:TDE RS12820
gene id: 243275:TDE_RS12820
uniprot id: Q73J53
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

243275:TDE RS12710
gene id: 243275:TDE_RS12710
uniprot id: Q73J76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

243275:TDE RS06235
gene id: 243275:TDE_RS06235
uniprot id: Q73N55
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

243275:TDE RS09875
gene id: 243275:TDE_RS09875
uniprot id: Q73KY3
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

243275:TDE RS03635
gene id: 243275:TDE_RS03635
uniprot id: Q73PP7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

243275:TDE RS05565
gene id: 243275:TDE_RS05565
uniprot id: Q73NJ0
names: Similarity
messages: Belongs to the ParB family.

243275:TDE RS13090
gene id: 243275:TDE_RS13090
uniprot id: Q73IZ6
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS12040
gene id: 243275:TDE_RS12040
uniprot id: Q73K07
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS09905
gene id: 243275:TDE_RS09905
uniprot id: P61748
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

243275:TDE RS10420
gene id: 243275:TDE_RS10420
uniprot id: Q73KL4
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS06960
gene id: 243275:TDE_RS06960
uniprot id: Q73MQ4
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS12145
gene id: 243275:TDE_RS12145
uniprot id: Q73K12
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

243275:TDE RS05850
gene id: 243275:TDE_RS05850
uniprot id: Q73ND7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cytoplasm
messages: Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum.

243275:TDE RS10185
gene id: 243275:TDE_RS10185
uniprot id: Q73KR6
names: Similarity
messages: Belongs to the UPF0178 family.

243275:TDE RS05755
gene id: 243275:TDE_RS05755
uniprot id: Q73NF4
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS01345
gene id: 243275:TDE_RS01345
uniprot id: Q73R19
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS10820
gene id: 243275:TDE_RS10820
uniprot id: Q73KC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

243275:TDE RS10570
gene id: 243275:TDE_RS10570
uniprot id: Q73KI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

243275:TDE RS06750
gene id: 243275:TDE_RS06750
uniprot id: Q73MU8
names: Subcellular Location Annotation
messages: Periplasmic flagellum

243275:TDE RS05065
gene id: 243275:TDE_RS05065
uniprot id: Q73NU0
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS03335
gene id: 243275:TDE_RS03335
uniprot id: Q73PV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

243275:TDE RS07900
gene id: 243275:TDE_RS07900
uniprot id: Q73M58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

243275:TDE RS08285
gene id: 243275:TDE_RS08285
uniprot id: Q73LY2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

243275:TDE RS06620
gene id: 243275:TDE_RS06620
uniprot id: Q73MX5
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

243275:TDE RS04455
gene id: 243275:TDE_RS04455
uniprot id: Q73P73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

243275:TDE RS04675
gene id: 243275:TDE_RS04675
uniprot id: Q73P26
names: Similarity
messages: Belongs to the UPF0758 family.

243275:TDE RS10500
gene id: 243275:TDE_RS10500
uniprot id: Q73KJ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

243275:TDE RS09650
gene id: 243275:TDE_RS09650
uniprot id: Q73L28
names: Caution
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243275:TDE RS05740
gene id: 243275:TDE_RS05740
uniprot id: Q73NF8
names: Similarity
messages: Belongs to the peptidase S9A family.

243275:TDE RS09915
gene id: 243275:TDE_RS09915
uniprot id: Q73KX5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

243275:TDE RS12995
gene id: 243275:TDE_RS12995
uniprot id: F7IU54
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

243275:TDE RS10150
gene id: 243275:TDE_RS10150
uniprot id: Q73KS3
names: Similarity
messages: Belongs to the UPF0597 family.

243275:TDE RS03300
gene id: 243275:TDE_RS03300
uniprot id: Q73PW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

243275:TDE RS11155
gene id: 243275:TDE_RS11155
uniprot id: Q73K61
names: Similarity
messages: Belongs to the leucine-binding protein family.

243275:TDE RS06745
gene id: 243275:TDE_RS06745
uniprot id: Q73MU9
names: Subcellular Location Annotation
messages: Periplasmic flagellum

243275:TDE RS10625
gene id: 243275:TDE_RS10625
uniprot id: Q73KG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Membrane

243275:TDE RS00475
gene id: 243275:TDE_RS00475
uniprot id: Q73RJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

243275:TDE RS04040
gene id: 243275:TDE_RS04040
uniprot id: Q73PG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

243275:TDE RS11305
gene id: 243275:TDE_RS11305
uniprot id: Q73JM2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243275:TDE RS07545
gene id: 243275:TDE_RS07545
uniprot id: Q73MD3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

243275:TDE RS04500
gene id: 243275:TDE_RS04500
uniprot id: Q73P62
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

243275:TDE RS00235
gene id: 243275:TDE_RS00235
uniprot id: Q73RP0
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS03200
gene id: 243275:TDE_RS03200
uniprot id: Q73PY2
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

243275:TDE RS00215
gene id: 243275:TDE_RS00215
uniprot id: Q73RP4
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

243275:TDE RS12180
gene id: 243275:TDE_RS12180
uniprot id: Q73K31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

243275:TDE RS03740
gene id: 243275:TDE_RS03740
uniprot id: Q73PM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

243275:TDE RS12060
gene id: 243275:TDE_RS12060
uniprot id: Q73K03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

243275:TDE RS13035
gene id: 243275:TDE_RS13035
uniprot id: F7IW18
names: Similarity
messages: Belongs to the FlgD family.

243275:TDE RS05840
gene id: 243275:TDE_RS05840
uniprot id: F7IVH0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

243275:TDE RS12170
gene id: 243275:TDE_RS12170
uniprot id: Q73K33
names: Similarity
messages: Belongs to the peptidase C69 family.

243275:TDE RS09190
gene id: 243275:TDE_RS09190
uniprot id: Q73LC7
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

243275:TDE RS02170
gene id: 243275:TDE_RS02170
uniprot id: Q73QJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

243275:TDE RS08290
gene id: 243275:TDE_RS08290
uniprot id: Q73LY1
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS11250
gene id: 243275:TDE_RS11250
uniprot id: Q73K40
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

243275:TDE RS06155
gene id: 243275:TDE_RS06155
uniprot id: Q73N71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

243275:TDE RS05295
gene id: 243275:TDE_RS05295
uniprot id: Q73NP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

243275:TDE RS01035
gene id: 243275:TDE_RS01035
uniprot id: Q73R77
names: Disruption Phenotype
names: Function
messages: Cyclic-di-GMP binding protein that plays important roles in motility, chemotaxis, biofilm formation and virulence.
messages: Mutants are less motile, reverse more frequently than the wild-type cells, and form less biofilm. Invasiveness and ability to induce skin abscesses and host humoral immune responses are significantly attenuated.

243275:TDE RS09485
gene id: 243275:TDE_RS09485
uniprot id: Q73L64
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

243275:TDE RS01995
gene id: 243275:TDE_RS01995
uniprot id: Q73QN3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

243275:TDE RS00410
gene id: 243275:TDE_RS00410
uniprot id: Q73RK8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

243275:TDE RS01635
gene id: 243275:TDE_RS01635
uniprot id: Q73QV8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

243275:TDE RS11995
gene id: 243275:TDE_RS11995
uniprot id: Q73JZ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

243275:TDE RS01165
gene id: 243275:TDE_RS01165
uniprot id: Q73R54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

243275:TDE RS00730
gene id: 243275:TDE_RS00730
uniprot id: Q73RD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

243275:TDE RS06945
gene id: 243275:TDE_RS06945
uniprot id: Q73MQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

243275:TDE RS01445
gene id: 243275:TDE_RS01445
uniprot id: Q73QZ8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

243275:TDE RS01625
gene id: 243275:TDE_RS01625
uniprot id: Q73QW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

243275:TDE RS13030
gene id: 243275:TDE_RS13030
uniprot id: F7IUZ4
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

243275:TDE RS07660
gene id: 243275:TDE_RS07660
uniprot id: Q73MA9
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS11840
gene id: 243275:TDE_RS11840
uniprot id: Q73JV0
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS12875
gene id: 243275:TDE_RS12875
uniprot id: Q73J38
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

243275:TDE RS00700
gene id: 243275:TDE_RS00700
uniprot id: Q73RE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

243275:TDE RS00325
gene id: 243275:TDE_RS00325
uniprot id: Q73RM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer.

243275:TDE RS07050
gene id: 243275:TDE_RS07050
uniprot id: Q73MN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Periplasm
messages: Periplasmic flagellum
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.

243275:TDE RS05955
gene id: 243275:TDE_RS05955
uniprot id: Q73NB3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

243275:TDE RS06550
gene id: 243275:TDE_RS06550
uniprot id: Q73MZ0
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

243275:TDE RS04765
gene id: 243275:TDE_RS04765
uniprot id: Q73P08
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

243275:TDE RS03750
gene id: 243275:TDE_RS03750
uniprot id: Q73PM4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

243275:TDE RS04875
gene id: 243275:TDE_RS04875
uniprot id: Q73NY2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

243275:TDE RS04785
gene id: 243275:TDE_RS04785
uniprot id: Q73P03
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

243275:TDE RS02175
gene id: 243275:TDE_RS02175
uniprot id: Q73QJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

243275:TDE RS01810
gene id: 243275:TDE_RS01810
uniprot id: Q73QS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

243275:TDE RS06385
gene id: 243275:TDE_RS06385
uniprot id: Q73N21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

243275:TDE RS08045
gene id: 243275:TDE_RS08045
uniprot id: Q73M31
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS11755
gene id: 243275:TDE_RS11755
uniprot id: Q73JU4
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

243275:TDE RS11465
gene id: 243275:TDE_RS11465
uniprot id: Q73JJ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

243275:TDE RS09665
gene id: 243275:TDE_RS09665
uniprot id: Q73L25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

243275:TDE RS08040
gene id: 243275:TDE_RS08040
uniprot id: Q73M32
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

243275:TDE RS07090
gene id: 243275:TDE_RS07090
uniprot id: Q73MM6
names: Similarity
messages: Belongs to the peptidase M24B family.

243275:TDE RS02070
gene id: 243275:TDE_RS02070
uniprot id: Q73QL6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

243275:TDE RS03700
gene id: 243275:TDE_RS03700
uniprot id: Q73PN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

243275:TDE RS11645
gene id: 243275:TDE_RS11645
uniprot id: Q73JR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

243275:TDE RS11585
gene id: 243275:TDE_RS11585
uniprot id: Q73JQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

243275:TDE RS11055
gene id: 243275:TDE_RS11055
uniprot id: Q73K79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

243275:TDE RS05315
gene id: 243275:TDE_RS05315
uniprot id: Q73NP1
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS09260
gene id: 243275:TDE_RS09260
uniprot id: Q73LB4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

243275:TDE RS08210
gene id: 243275:TDE_RS08210
uniprot id: P62421
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

243275:TDE RS09660
gene id: 243275:TDE_RS09660
uniprot id: Q73L26
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS07395
gene id: 243275:TDE_RS07395
uniprot id: Q73MG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

243275:TDE RS08060
gene id: 243275:TDE_RS08060
uniprot id: Q73M29
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

243275:TDE RS01005
gene id: 243275:TDE_RS01005
uniprot id: Q73R82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

243275:TDE RS12260
gene id: 243275:TDE_RS12260
uniprot id: Q73JH3
names: Similarity
messages: Belongs to the Skp family.

243275:TDE RS09065
gene id: 243275:TDE_RS09065
uniprot id: Q73LF5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

243275:TDE RS05125
gene id: 243275:TDE_RS05125
uniprot id: Q73NS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

243275:TDE RS07240
gene id: 243275:TDE_RS07240
uniprot id: Q73MJ7
names: Similarity
messages: Belongs to the UPF0423 family.

243275:TDE RS04210
gene id: 243275:TDE_RS04210
uniprot id: Q73PC9
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

243275:TDE RS00580
gene id: 243275:TDE_RS00580
uniprot id: Q73RH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

243275:TDE RS04520
gene id: 243275:TDE_RS04520
uniprot id: Q73P58
names: Similarity
messages: Belongs to the peptidase C40 family.

243275:TDE RS04275
gene id: 243275:TDE_RS04275
uniprot id: Q73PB4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

243275:TDE RS10375
gene id: 243275:TDE_RS10375
uniprot id: Q73KM4
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

243275:TDE RS10100
gene id: 243275:TDE_RS10100
uniprot id: Q73KT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).

243275:TDE RS11705
gene id: 243275:TDE_RS11705
uniprot id: P61188
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

243275:TDE RS02850
gene id: 243275:TDE_RS02850
uniprot id: Q73Q56
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

243275:TDE RS03705
gene id: 243275:TDE_RS03705
uniprot id: Q73PN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

243275:TDE RS10460
gene id: 243275:TDE_RS10460
uniprot id: Q73KK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

243275:TDE RS10855
gene id: 243275:TDE_RS10855
uniprot id: P61038
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane

243275:TDE RS10615
gene id: 243275:TDE_RS10615
uniprot id: Q73KH1
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

243275:TDE RS11360
gene id: 243275:TDE_RS11360
uniprot id: Q73JL1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

243275:TDE RS00220
gene id: 243275:TDE_RS00220
uniprot id: Q73RP3
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

243275:TDE RS06405
gene id: 243275:TDE_RS06405
uniprot id: Q73N17
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

243275:TDE RS08835
gene id: 243275:TDE_RS08835
uniprot id: Q73LL1
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS00290
gene id: 243275:TDE_RS00290
uniprot id: Q73RN2
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

243275:TDE RS12565
gene id: 243275:TDE_RS12565
uniprot id: Q73JA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243275:TDE RS07980
gene id: 243275:TDE_RS07980
uniprot id: Q73M42
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS03120
gene id: 243275:TDE_RS03120
uniprot id: P62646
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

243275:TDE RS00280
gene id: 243275:TDE_RS00280
uniprot id: Q3V8B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

243275:TDE RS10205
gene id: 243275:TDE_RS10205
uniprot id: Q73KR2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

243275:TDE RS07770
gene id: 243275:TDE_RS07770
uniprot id: Q73M84
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

243275:TDE RS00650
gene id: 243275:TDE_RS00650
uniprot id: Q73RF9
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS00840
gene id: 243275:TDE_RS00840
uniprot id: Q73RB8
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

243275:TDE RS05420
gene id: 243275:TDE_RS05420
uniprot id: Q73NM0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

243275:TDE RS06785
gene id: 243275:TDE_RS06785
uniprot id: Q73MU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

243275:TDE RS05870
gene id: 243275:TDE_RS05870
uniprot id: Q73ND3
names: Similarity
messages: Belongs to the DtxR/MntR family.

243275:TDE RS13100
gene id: 243275:TDE_RS13100
uniprot id: Q73IZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

243275:TDE RS08055
gene id: 243275:TDE_RS08055
uniprot id: Q73M30
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

243275:TDE RS12900
gene id: 243275:TDE_RS12900
uniprot id: Q73J33
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

243275:TDE RS07835
gene id: 243275:TDE_RS07835
uniprot id: Q73M72
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

243275:TDE RS03315
gene id: 243275:TDE_RS03315
uniprot id: Q73PW0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

243275:TDE RS11080
gene id: 243275:TDE_RS11080
uniprot id: P61339
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

243275:TDE RS03865
gene id: 243275:TDE_RS03865
uniprot id: Q73PK1
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS09640
gene id: 243275:TDE_RS09640
uniprot id: Q73L30
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

243275:TDE RS04550
gene id: 243275:TDE_RS04550
uniprot id: Q73P51
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

243275:TDE RS12550
gene id: 243275:TDE_RS12550
uniprot id: Q73JB2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

243275:TDE RS07930
gene id: 243275:TDE_RS07930
uniprot id: Q73M53
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

243275:TDE RS00425
gene id: 243275:TDE_RS00425
uniprot id: Q73RK5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

243275:TDE RS04265
gene id: 243275:TDE_RS04265
uniprot id: Q73PB6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

243275:TDE RS00755
gene id: 243275:TDE_RS00755
uniprot id: Q73RD3
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

243275:TDE RS01605
gene id: 243275:TDE_RS01605
uniprot id: Q73QW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

243275:TDE RS06160
gene id: 243275:TDE_RS06160
uniprot id: Q73N70
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

243275:TDE RS03435
gene id: 243275:TDE_RS03435
uniprot id: Q73PT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

243275:TDE RS02830
gene id: 243275:TDE_RS02830
uniprot id: Q73Q60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

243275:TDE RS09910
gene id: 243275:TDE_RS09910
uniprot id: Q73KX6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

243275:TDE RS01610
gene id: 243275:TDE_RS01610
uniprot id: Q73QW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

243275:TDE RS03075
gene id: 243275:TDE_RS03075
uniprot id: Q73Q05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

243275:TDE RS03660
gene id: 243275:TDE_RS03660
uniprot id: Q73PP2
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS07210
gene id: 243275:TDE_RS07210
uniprot id: Q73MK3
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS09015
gene id: 243275:TDE_RS09015
uniprot id: Q73LG8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

243275:TDE RS04555
gene id: 243275:TDE_RS04555
uniprot id: Q73P50
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

243275:TDE RS10250
gene id: 243275:TDE_RS10250
uniprot id: Q73KQ2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

243275:TDE RS07780
gene id: 243275:TDE_RS07780
uniprot id: Q73M82
names: Similarity
messages: Belongs to the GcvT family.

243275:TDE RS12725
gene id: 243275:TDE_RS12725
uniprot id: Q73J72
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS06475
gene id: 243275:TDE_RS06475
uniprot id: Q73N05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

243275:TDE RS13095
gene id: 243275:TDE_RS13095
uniprot id: Q73IZ5
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS08035
gene id: 243275:TDE_RS08035
uniprot id: Q73M33
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243275:TDE RS08115
gene id: 243275:TDE_RS08115
uniprot id: Q73M16
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

243275:TDE RS02155
gene id: 243275:TDE_RS02155
uniprot id: Q73QJ8
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS13080
gene id: 243275:TDE_RS13080
uniprot id: Q73IZ9
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS02320
gene id: 243275:TDE_RS02320
uniprot id: Q73QG3
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

243275:TDE RS06965
gene id: 243275:TDE_RS06965
uniprot id: Q73MQ3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

243275:TDE RS04695
gene id: 243275:TDE_RS04695
uniprot id: Q73P20
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

243275:TDE RS02185
gene id: 243275:TDE_RS02185
uniprot id: Q73QJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

243275:TDE RS05795
gene id: 243275:TDE_RS05795
uniprot id: Q73NE6
names: Similarity
messages: Belongs to the DprA/Smf family.

243275:TDE RS10200
gene id: 243275:TDE_RS10200
uniprot id: Q73KR3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

243275:TDE RS05210
gene id: 243275:TDE_RS05210
uniprot id: Q73NR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

243275:TDE RS11690
gene id: 243275:TDE_RS11690
uniprot id: Q73JT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

243275:TDE RS08005
gene id: 243275:TDE_RS08005
uniprot id: Q73M39
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

243275:TDE RS10480
gene id: 243275:TDE_RS10480
uniprot id: Q73KK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.
messages: The complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

243275:TDE RS02335
gene id: 243275:TDE_RS02335
uniprot id: Q73QG0
names: Subcellular Location Annotation
messages: Membrane

243275:TDE RS03450
gene id: 243275:TDE_RS03450
uniprot id: Q73PT2
names: Similarity
messages: Belongs to the polysaccharide synthase family.

243275:TDE RS09900
gene id: 243275:TDE_RS09900
uniprot id: Q73KX8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

243275:TDE RS06110
gene id: 243275:TDE_RS06110
uniprot id: Q73N81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

243275:TDE RS01955
gene id: 243275:TDE_RS01955
uniprot id: Q73QP3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

243275:TDE RS06940
gene id: 243275:TDE_RS06940
uniprot id: Q73MQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

243275:TDE RS00570
gene id: 243275:TDE_RS00570
uniprot id: Q73RH4
names: Similarity
messages: Belongs to the DtxR/MntR family.

243275:TDE RS08015
gene id: 243275:TDE_RS08015
uniprot id: Q73M37
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

243275:TDE RS03780
gene id: 243275:TDE_RS03780
uniprot id: Q73PL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

243275:TDE RS05800
gene id: 243275:TDE_RS05800
uniprot id: Q73NE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

243275:TDE RS01370
gene id: 243275:TDE_RS01370
uniprot id: Q73R14
names: Similarity
messages: Belongs to the peptidase S33 family.

243275:TDE RS13225
gene id: 243275:TDE_RS13225
uniprot id: Q73R53
names: Similarity
messages: Belongs to the thioredoxin family.

243275:TDE RS11275
gene id: 243275:TDE_RS11275
uniprot id: Q73JN0
names: Similarity
messages: Belongs to the disproportionating enzyme family.

243275:TDE RS01000
gene id: 243275:TDE_RS01000
uniprot id: Q73R83
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

243275:TDE RS03015
gene id: 243275:TDE_RS03015
uniprot id: Q73Q17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

243275:TDE RS06445
gene id: 243275:TDE_RS06445
uniprot id: Q73N10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.