243231:GS RS13030
gene id: 243231:GS_RS13030
uniprot id: Q749Z8
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

243231:GS RS05380
gene id: 243231:GS_RS05380
uniprot id: P61532
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

243231:GS RS10715
gene id: 243231:GS_RS10715
uniprot id: Q74BA7
names: Similarity
messages: Belongs to the P(II) protein family.

243231:GS RS09385
gene id: 243231:GS_RS09385
uniprot id: Q74C11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

243231:GS RS09375
gene id: 243231:GS_RS09375
uniprot id: Q74C13
names: Similarity
messages: Belongs to the ros/MucR family.

243231:GS RS15495
gene id: 243231:GS_RS15495
uniprot id: Q748C2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

243231:GS RS11430
gene id: 243231:GS_RS11430
uniprot id: Q74AS4
names: Similarity
messages: Belongs to the peptidase C40 family.

243231:GS RS06605
gene id: 243231:GS_RS06605
uniprot id: Q74DI9
names: Cofactor
messages: Binds 1 zinc ion per subunit.

243231:GS RS12160
gene id: 243231:GS_RS12160
uniprot id: Q74AF7
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

243231:GS RS10315
gene id: 243231:GS_RS10315
uniprot id: Q74BI8
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

243231:GS RS07905
gene id: 243231:GS_RS07905
uniprot id: Q74CT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

243231:GS RS07945
gene id: 243231:GS_RS07945
uniprot id: Q74CS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

243231:GS RS00110
gene id: 243231:GS_RS00110
uniprot id: Q74H71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

243231:GS RS13185
gene id: 243231:GS_RS13185
uniprot id: Q749X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

243231:GS RS03040
gene id: 243231:GS_RS03040
uniprot id: Q74FJ7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

243231:GS RS00825
gene id: 243231:GS_RS00825
uniprot id: Q74GT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

243231:GS RS17275
gene id: 243231:GS_RS17275
uniprot id: Q746R9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

243231:GS RS12180
gene id: 243231:GS_RS12180
uniprot id: Q74AF3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243231:GS RS13370
gene id: 243231:GS_RS13370
uniprot id: Q749T6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

243231:GS RS05200
gene id: 243231:GS_RS05200
uniprot id: Q74EC2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243231:GS RS00875
gene id: 243231:GS_RS00875
uniprot id: Q74GS4
names: Similarity
messages: Belongs to the UPF0178 family.

243231:GS RS03655
gene id: 243231:GS_RS03655
uniprot id: Q74F76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243231:GS RS07795
gene id: 243231:GS_RS07795
uniprot id: Q74CV7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

243231:GS RS02430
gene id: 243231:GS_RS02430
uniprot id: Q74FW6
names: Disruption Phenotype
names: Function
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the conversion of threonine to 2-oxobutanoate and ammonia. Functions in the threonine-dependent pathway of isoleucine biosynthesis, which is the minor pathway for isoleucine biosynthesis in G.sulfurreducens. Also displays serine ammonia-lyase activity, yielding pyruvate from L-serine.
messages: Cells lacking this gene show undetectable threonine ammonia-lyase and serine ammonia-lyase activities. They are capable of growth in the absence of isoleucine, whereas mutants lacking both tdcB and the citramalate synthase cimA are auxotrophs for isoleucine.

243231:GS RS15420
gene id: 243231:GS_RS15420
uniprot id: Q748D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

243231:GS RS07885
gene id: 243231:GS_RS07885
uniprot id: Q74CU0
names: Function
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
messages: tRNA nucleotidyltransferase involved in the synthesis of the tRNA CCA terminus. Adds the terminal adenosine residue to tRNA.

243231:GS RS02120
gene id: 243231:GS_RS02120
uniprot id: Q74G26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

243231:GS RS03445
gene id: 243231:GS_RS03445
uniprot id: Q74FB8
names: Similarity
messages: Belongs to the SUI1 family.

243231:GS RS00090
gene id: 243231:GS_RS00090
uniprot id: Q74H75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

243231:GS RS15675
gene id: 243231:GS_RS15675
uniprot id: Q747Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

243231:GS RS02465
gene id: 243231:GS_RS02465
uniprot id: Q74FV9
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

243231:GS RS07565
gene id: 243231:GS_RS07565
uniprot id: Q74D01
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

243231:GS RS07935
gene id: 243231:GS_RS07935
uniprot id: P60344
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

243231:GS RS15800
gene id: 243231:GS_RS15800
uniprot id: Q747W9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

243231:GS RS17060
gene id: 243231:GS_RS17060
uniprot id: Q746W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

243231:GS RS11245
gene id: 243231:GS_RS11245
uniprot id: Q74AW0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

243231:GS RS09660
gene id: 243231:GS_RS09660
uniprot id: P61333
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

243231:GS RS10445
gene id: 243231:GS_RS10445
uniprot id: Q74BG0
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

243231:GS RS14330
gene id: 243231:GS_RS14330
uniprot id: P60401
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

243231:GS RS07555
gene id: 243231:GS_RS07555
uniprot id: Q74D03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

243231:GS RS07010
gene id: 243231:GS_RS07010
uniprot id: Q74DA7
names: Similarity
messages: Belongs to the UPF0251 family.

243231:GS RS15615
gene id: 243231:GS_RS15615
uniprot id: Q748A7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243231:GS RS16290
gene id: 243231:GS_RS16290
uniprot id: Q747L1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

243231:GS RS03435
gene id: 243231:GS_RS03435
uniprot id: Q74FC0
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS14365
gene id: 243231:GS_RS14365
uniprot id: Q748Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

243231:GS RS04240
gene id: 243231:GS_RS04240
uniprot id: Q74EW3
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

243231:GS RS11925
gene id: 243231:GS_RS11925
uniprot id: Q74AH7
names: Similarity
messages: Belongs to the TrpF family.

243231:GS RS09820
gene id: 243231:GS_RS09820
uniprot id: Q74BS3
names: Similarity
messages: Belongs to the asparagine synthetase family.

243231:GS RS08770
gene id: 243231:GS_RS08770
uniprot id: Q74CB8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

243231:GS RS00785
gene id: 243231:GS_RS00785
uniprot id: Q74GU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

243231:GS RS12110
gene id: 243231:GS_RS12110
uniprot id: Q74B23
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

243231:GS RS09200
gene id: 243231:GS_RS09200
uniprot id: Q74C41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

243231:GS RS08765
gene id: 243231:GS_RS08765
uniprot id: Q74CB9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Cytoplasm
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.

243231:GS RS10730
gene id: 243231:GS_RS10730
uniprot id: Q74BA4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

243231:GS RS15355
gene id: 243231:GS_RS15355
uniprot id: Q748E6
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

243231:GS RS08020
gene id: 243231:GS_RS08020
uniprot id: Q74CR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

243231:GS RS13985
gene id: 243231:GS_RS13985
uniprot id: Q749F6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

243231:GS RS14475
gene id: 243231:GS_RS14475
uniprot id: P60350
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

243231:GS RS05055
gene id: 243231:GS_RS05055
uniprot id: Q74EF4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

243231:GS RS14590
gene id: 243231:GS_RS14590
uniprot id: Q748V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

243231:GS RS07770
gene id: 243231:GS_RS07770
uniprot id: Q74CW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

243231:GS RS06315
gene id: 243231:GS_RS06315
uniprot id: Q74DP8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

243231:GS RS01920
gene id: 243231:GS_RS01920
uniprot id: Q74G62
names: Similarity
messages: Belongs to the UPF0758 family.

243231:GS RS09120
gene id: 243231:GS_RS09120
uniprot id: Q74C57
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

243231:GS RS08530
gene id: 243231:GS_RS08530
uniprot id: Q74CG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

243231:GS RS08430
gene id: 243231:GS_RS08430
uniprot id: Q74CI3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243231:GS RS15565
gene id: 243231:GS_RS15565
uniprot id: P60885
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

243231:GS RS02000
gene id: 243231:GS_RS02000
uniprot id: Q74G47
names: Similarity
messages: Belongs to the hemerythrin family.

243231:GS RS15140
gene id: 243231:GS_RS15140
uniprot id: Q748I9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

243231:GS RS11595
gene id: 243231:GS_RS11595
uniprot id: Q74AP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

243231:GS RS15590
gene id: 243231:GS_RS15590
uniprot id: Q748B2
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

243231:GS RS08380
gene id: 243231:GS_RS08380
uniprot id: Q74CJ3
names: Similarity
messages: Belongs to the archease family.

243231:GS RS04175
gene id: 243231:GS_RS04175
uniprot id: Q74EY0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

243231:GS RS01720
gene id: 243231:GS_RS01720
uniprot id: Q74GA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

243231:GS RS17310
gene id: 243231:GS_RS17310
uniprot id: Q746R2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

243231:GS RS12515
gene id: 243231:GS_RS12515
uniprot id: Q74A99
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS14290
gene id: 243231:GS_RS14290
uniprot id: P60740
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

243231:GS RS11930
gene id: 243231:GS_RS11930
uniprot id: Q74AH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

243231:GS RS01870
gene id: 243231:GS_RS01870
uniprot id: Q74G71
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

243231:GS RS02200
gene id: 243231:GS_RS02200
uniprot id: Q74G12
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243231:GS RS08455
gene id: 243231:GS_RS08455
uniprot id: Q74CH8
names: Similarity
messages: Belongs to the threonine synthase family.

243231:GS RS10110
gene id: 243231:GS_RS10110
uniprot id: Q74BM9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

243231:GS RS11040
gene id: 243231:GS_RS11040
uniprot id: Q74B44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

243231:GS RS08810
gene id: 243231:GS_RS08810
uniprot id: Q74CB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

243231:GS RS07215
gene id: 243231:GS_RS07215
uniprot id: Q74D67
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

243231:GS RS10055
gene id: 243231:GS_RS10055
uniprot id: Q74BP0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

243231:GS RS06375
gene id: 243231:GS_RS06375
uniprot id: Q74DN6
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS16645
gene id: 243231:GS_RS16645
uniprot id: Q747E6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

243231:GS RS03045
gene id: 243231:GS_RS03045
uniprot id: G5EBD6
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

243231:GS RS12380
gene id: 243231:GS_RS12380
uniprot id: Q74AC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

243231:GS RS15310
gene id: 243231:GS_RS15310
uniprot id: Q748F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

243231:GS RS03725
gene id: 243231:GS_RS03725
uniprot id: Q74F59
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243231:GS RS12780
gene id: 243231:GS_RS12780
uniprot id: Q74A47
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

243231:GS RS16255
gene id: 243231:GS_RS16255
uniprot id: Q747L9
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

243231:GS RS03210
gene id: 243231:GS_RS03210
uniprot id: Q74FG1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

243231:GS RS15520
gene id: 243231:GS_RS15520
uniprot id: Q748B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

243231:GS RS11870
gene id: 243231:GS_RS11870
uniprot id: Q74AI8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

243231:GS RS02725
gene id: 243231:GS_RS02725
uniprot id: Q74FR0
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

243231:GS RS10105
gene id: 243231:GS_RS10105
uniprot id: Q74BN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
messages: Homodimer.

243231:GS RS02965
gene id: 243231:GS_RS02965
uniprot id: Q74FL1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243231:GS RS13660
gene id: 243231:GS_RS13660
uniprot id: Q749M3
names: Subcellular Location Annotation
messages: Periplasm

243231:GS RS00180
gene id: 243231:GS_RS00180
uniprot id: Q74H57
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

243231:GS RS16890
gene id: 243231:GS_RS16890
uniprot id: Q746Z5
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS07395
gene id: 243231:GS_RS07395
uniprot id: Q74D33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

243231:GS RS08665
gene id: 243231:GS_RS08665
uniprot id: Q74CE0
names: Similarity
messages: Belongs to the leucine-binding protein family.

243231:GS RS17340
gene id: 243231:GS_RS17340
uniprot id: Q746Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

243231:GS RS07290
gene id: 243231:GS_RS07290
uniprot id: Q74D54
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

243231:GS RS16650
gene id: 243231:GS_RS16650
uniprot id: Q747E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

243231:GS RS09600
gene id: 243231:GS_RS09600
uniprot id: Q74BX0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

243231:GS RS05735
gene id: 243231:GS_RS05735
uniprot id: P62639
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

243231:GS RS08135
gene id: 243231:GS_RS08135
uniprot id: Q74CP4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

243231:GS RS08095
gene id: 243231:GS_RS08095
uniprot id: Q74CQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

243231:GS RS06955
gene id: 243231:GS_RS06955
uniprot id: Q74DB8
names: Similarity
messages: Belongs to the SCO1/2 family.

243231:GS RS17255
gene id: 243231:GS_RS17255
uniprot id: Q746S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

243231:GS RS07900
gene id: 243231:GS_RS07900
uniprot id: Q74CT7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

243231:GS RS07255
gene id: 243231:GS_RS07255
uniprot id: Q74D59
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

243231:GS RS06735
gene id: 243231:GS_RS06735
uniprot id: Q74DG3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

243231:GS RS11355
gene id: 243231:GS_RS11355
uniprot id: Q74AT8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

243231:GS RS11845
gene id: 243231:GS_RS11845
uniprot id: Q74AJ3
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

243231:GS RS06170
gene id: 243231:GS_RS06170
uniprot id: Q74DS6
names: Similarity
messages: Belongs to the glutamate synthase family.

243231:GS RS15095
gene id: 243231:GS_RS15095
uniprot id: Q748J9
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS01930
gene id: 243231:GS_RS01930
uniprot id: Q74G61
names: Similarity
messages: Belongs to the UPF0111 family.

243231:GS RS08520
gene id: 243231:GS_RS08520
uniprot id: Q74CG6
names: Similarity
messages: Belongs to the group II decarboxylase family.

243231:GS RS14900
gene id: 243231:GS_RS14900
uniprot id: Q748N9
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

243231:GS RS14075
gene id: 243231:GS_RS14075
uniprot id: Q749D8
names: Similarity
messages: Belongs to the NifX/NifY family.

243231:GS RS12905
gene id: 243231:GS_RS12905
uniprot id: Q74A22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

243231:GS RS00590
gene id: 243231:GS_RS00590
uniprot id: Q74GY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

243231:GS RS16765
gene id: 243231:GS_RS16765
uniprot id: Q747C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

243231:GS RS14135
gene id: 243231:GS_RS14135
uniprot id: Q749C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Cell membrane

243231:GS RS10810
gene id: 243231:GS_RS10810
uniprot id: Q74B90
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243231:GS RS01925
gene id: 243231:GS_RS01925
uniprot id: P60938
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

243231:GS RS14885
gene id: 243231:GS_RS14885
uniprot id: Q748P2
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS03595
gene id: 243231:GS_RS03595
uniprot id: Q74F89
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

243231:GS RS15580
gene id: 243231:GS_RS15580
uniprot id: P60836
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity).
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

243231:GS RS10370
gene id: 243231:GS_RS10370
uniprot id: Q74BH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

243231:GS RS15000
gene id: 243231:GS_RS15000
uniprot id: Q748L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

243231:GS RS06620
gene id: 243231:GS_RS06620
uniprot id: Q74DI6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

243231:GS RS02045
gene id: 243231:GS_RS02045
uniprot id: Q74G38
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

243231:GS RS14420
gene id: 243231:GS_RS14420
uniprot id: Q748X9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

243231:GS RS05715
gene id: 243231:GS_RS05715
uniprot id: Q74E23
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243231:GS RS02475
gene id: 243231:GS_RS02475
uniprot id: Q74FV6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

243231:GS RS14905
gene id: 243231:GS_RS14905
uniprot id: Q748N8
names: Similarity
messages: Belongs to the NadC/ModD family.

243231:GS RS03535
gene id: 243231:GS_RS03535
uniprot id: Q74FA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

243231:GS RS13060
gene id: 243231:GS_RS13060
uniprot id: Q74DL9
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

243231:GS RS08580
gene id: 243231:GS_RS08580
uniprot id: Q74CF7
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

243231:GS RS16830
gene id: 243231:GS_RS16830
uniprot id: Q747A7
names: Similarity
messages: Belongs to the peptidase M16 family.

243231:GS RS08235
gene id: 243231:GS_RS08235
uniprot id: Q74CM3
names: Subunit
messages: Heterodimer of a large and a small subunit.

243231:GS RS07260
gene id: 243231:GS_RS07260
uniprot id: Q74D58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

243231:GS RS05375
gene id: 243231:GS_RS05375
uniprot id: Q74E87
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

243231:GS RS04315
gene id: 243231:GS_RS04315
uniprot id: Q74EU9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

243231:GS RS09670
gene id: 243231:GS_RS09670
uniprot id: Q74BW0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

243231:GS RS00635
gene id: 243231:GS_RS00635
uniprot id: Q74GX2
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

243231:GS RS14030
gene id: 243231:GS_RS14030
uniprot id: Q749E7
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

243231:GS RS10085
gene id: 243231:GS_RS10085
uniprot id: Q74BN4
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS12205
gene id: 243231:GS_RS12205
uniprot id: Q74AE8
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

243231:GS RS14225
gene id: 243231:GS_RS14225
uniprot id: Q749B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

243231:GS RS05285
gene id: 243231:GS_RS05285
uniprot id: Q74EA5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

243231:GS RS05460
gene id: 243231:GS_RS05460
uniprot id: Q74E69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

243231:GS RS14070
gene id: 243231:GS_RS14070
uniprot id: Q749D9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

243231:GS RS14830
gene id: 243231:GS_RS14830
uniprot id: Q748Q3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

243231:GS RS17360
gene id: 243231:GS_RS17360
uniprot id: P61469
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

243231:GS RS12155
gene id: 243231:GS_RS12155
uniprot id: Q74AF8
names: Subcellular Location Annotation
messages: Periplasm

243231:GS RS03315
gene id: 243231:GS_RS03315
uniprot id: Q74FE5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

243231:GS RS14315
gene id: 243231:GS_RS14315
uniprot id: Q748Z4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

243231:GS RS08905
gene id: 243231:GS_RS08905
uniprot id: Q74C91
names: Similarity
messages: Belongs to the GSP E family.

243231:GS RS02640
gene id: 243231:GS_RS02640
uniprot id: Q74FS7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

243231:GS RS02540
gene id: 243231:GS_RS02540
uniprot id: Q74FU6
names: Activity Regulation
names: Caution
names: Function
names: Induction
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Cytoplasm
messages: Expressed constitutively.
messages: Heterotetramer with 2 beta subunits.
messages: NADPH-dependent Fe(3+) reductase. Probably involved in acetate metabolism and not in the reduction of Fe(3+) chelates. Unable to utilize NADH or formate as electron donors. Unlike formate dehydrogenases, contains no W, Mo or Se. Substrates are Fe(3+)-nitrilotriacetate >> Fe(3+)-citrate or Fe(3+)-EDTA > Fe(3+)-oxyhydroxide. Catalyzes also the reduction of NADP(+) with reduced methyl viologen as electron donor. No activity with menadione as electron acceptor. May be alternatively involved in transferring electrons from reduced ferredoxin to NADP(+) and may serve as a major route for NADP regeneration.
messages: Not regulated by FAD or FMN.
messages: PubMed:17906154 suggests that SfrAB is involved in acetate metabolism and does not participate directly in the reduction of Fe(3+) chelates, as was initially proposed in PubMed:11443080.
messages: SfrA lacks the residues that are catalytically important in formate dehydrogenases, including a Cys residue which is a ligand to the heavy-metal atom (Mo or W) of the molybdopterin cofactor.

243231:GS RS12120
gene id: 243231:GS_RS12120
uniprot id: Q74B22
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

243231:GS RS11690
gene id: 243231:GS_RS11690
uniprot id: Q74AM4
names: Similarity
messages: Belongs to the CFA/CMAS family.

243231:GS RS00530
gene id: 243231:GS_RS00530
uniprot id: Q74GZ2
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS01410
gene id: 243231:GS_RS01410
uniprot id: Q74GG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

243231:GS RS06330
gene id: 243231:GS_RS06330
uniprot id: Q74DP5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

243231:GS RS01680
gene id: 243231:GS_RS01680
uniprot id: Q74GA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

243231:GS RS09480
gene id: 243231:GS_RS09480
uniprot id: Q74BZ3
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

243231:GS RS00015
gene id: 243231:GS_RS00015
uniprot id: Q74H90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

243231:GS RS07000
gene id: 243231:GS_RS07000
uniprot id: Q74DA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

243231:GS RS06785
gene id: 243231:GS_RS06785
uniprot id: Q74DF3
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

243231:GS RS17185
gene id: 243231:GS_RS17185
uniprot id: Q746T7
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS15265
gene id: 243231:GS_RS15265
uniprot id: Q748G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

243231:GS RS09735
gene id: 243231:GS_RS09735
uniprot id: Q74BU1
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243231:GS RS09050
gene id: 243231:GS_RS09050
uniprot id: Q74C70
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

243231:GS RS12240
gene id: 243231:GS_RS12240
uniprot id: Q74AE1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

243231:GS RS05470
gene id: 243231:GS_RS05470
uniprot id: Q74E67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

243231:GS RS00305
gene id: 243231:GS_RS00305
uniprot id: Q74H36
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity). The Cas4 region acts as a ssDNA exonuclease, while the Cas1 region acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette (By similarity).
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.
messages: In the C-terminal section; belongs to the CRISPR-associated endonuclease Cas1 family.
messages: In the N-terminal section; belongs to the CRISPR-associated exonuclease Cas4 family.

243231:GS RS03230
gene id: 243231:GS_RS03230
uniprot id: Q74FF7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243231:GS RS15320
gene id: 243231:GS_RS15320
uniprot id: Q748F1
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

243231:GS RS09665
gene id: 243231:GS_RS09665
uniprot id: Q74BW1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

243231:GS RS09015
gene id: 243231:GS_RS09015
uniprot id: Q74C76
names: Disruption Phenotype
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate. Makes part of the main pathway for isoleucine biosynthesis in G.sulfurreducens, i.e. the citramalate-dependent pathway.
messages: Cells lacking this gene show a great reduction in citramalate synthase activity and are capable of growth in the absence of isoleucine, whereas mutants lacking both cimA and the threonine ammonia-lyase tcdB are auxotrophs for isoleucine.

243231:GS RS03915
gene id: 243231:GS_RS03915
uniprot id: Q74F29
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

243231:GS RS05125
gene id: 243231:GS_RS05125
uniprot id: Q74ED8
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

243231:GS RS06370
gene id: 243231:GS_RS06370
uniprot id: Q74DN7
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS01440
gene id: 243231:GS_RS01440
uniprot id: Q74GF6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

243231:GS RS11030
gene id: 243231:GS_RS11030
uniprot id: Q74B46
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

243231:GS RS03900
gene id: 243231:GS_RS03900
uniprot id: Q74F32
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Heterodimer of a large and a small subunit.
messages: Periplasm

243231:GS RS16695
gene id: 243231:GS_RS16695
uniprot id: Q747D6
names: Similarity
messages: Belongs to the pyruvate kinase family.

243231:GS RS11865
gene id: 243231:GS_RS11865
uniprot id: Q74AI9
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

243231:GS RS06185
gene id: 243231:GS_RS06185
uniprot id: Q74DS3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

243231:GS RS11505
gene id: 243231:GS_RS11505
uniprot id: Q74AR1
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

243231:GS RS13510
gene id: 243231:GS_RS13510
uniprot id: Q749Q6
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS05730
gene id: 243231:GS_RS05730
uniprot id: Q74E20
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

243231:GS RS11205
gene id: 243231:GS_RS11205
uniprot id: Q74AW7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

243231:GS RS09950
gene id: 243231:GS_RS09950
uniprot id: Q74BR2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

243231:GS RS00665
gene id: 243231:GS_RS00665
uniprot id: Q74GW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

243231:GS RS02295
gene id: 243231:GS_RS02295
uniprot id: Q74FZ2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

243231:GS RS00600
gene id: 243231:GS_RS00600
uniprot id: Q3V8D3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

243231:GS RS01455
gene id: 243231:GS_RS01455
uniprot id: P62638
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

243231:GS RS16855
gene id: 243231:GS_RS16855
uniprot id: Q747A2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

243231:GS RS00235
gene id: 243231:GS_RS00235
uniprot id: Q74H50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

243231:GS RS16355
gene id: 243231:GS_RS16355
uniprot id: Q747J7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

243231:GS RS11215
gene id: 243231:GS_RS11215
uniprot id: Q74AW5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

243231:GS RS01530
gene id: 243231:GS_RS01530
uniprot id: Q74GD9
names: Similarity
messages: Belongs to the HupF/HypC family.

243231:GS RS16540
gene id: 243231:GS_RS16540
uniprot id: Q747G3
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

243231:GS RS11235
gene id: 243231:GS_RS11235
uniprot id: P60551
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

243231:GS RS03110
gene id: 243231:GS_RS03110
uniprot id: Q74FI2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243231:GS RS01275
gene id: 243231:GS_RS01275
uniprot id: Q74GJ0
names: Similarity
messages: Belongs to the hemerythrin family.

243231:GS RS14175
gene id: 243231:GS_RS14175
uniprot id: Q749B9
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS04780
gene id: 243231:GS_RS04780
uniprot id: Q74EL2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

243231:GS RS02700
gene id: 243231:GS_RS02700
uniprot id: Q74FR5
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

243231:GS RS12805
gene id: 243231:GS_RS12805
uniprot id: Q74A42
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

243231:GS RS04280
gene id: 243231:GS_RS04280
uniprot id: Q74EV6
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS04610
gene id: 243231:GS_RS04610
uniprot id: Q74EP6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243231:GS RS12285
gene id: 243231:GS_RS12285
uniprot id: Q74AD3
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

243231:GS RS01525
gene id: 243231:GS_RS01525
uniprot id: Q74GE0
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

243231:GS RS09315
gene id: 243231:GS_RS09315
uniprot id: Q74C20
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS07825
gene id: 243231:GS_RS07825
uniprot id: Q74CV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

243231:GS RS06925
gene id: 243231:GS_RS06925
uniprot id: Q74DC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

243231:GS RS05635
gene id: 243231:GS_RS05635
uniprot id: G5EBD4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

243231:GS RS08920
gene id: 243231:GS_RS08920
uniprot id: Q74C88
names: Similarity
messages: Belongs to the cytochrome c-552 family.

243231:GS RS09730
gene id: 243231:GS_RS09730
uniprot id: Q74BU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

243231:GS RS03320
gene id: 243231:GS_RS03320
uniprot id: Q74FE4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

243231:GS RS00360
gene id: 243231:GS_RS00360
uniprot id: Q74H26
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

243231:GS RS03920
gene id: 243231:GS_RS03920
uniprot id: Q74F28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

243231:GS RS13675
gene id: 243231:GS_RS13675
uniprot id: Q749M0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

243231:GS RS09440
gene id: 243231:GS_RS09440
uniprot id: Q74C01
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS13555
gene id: 243231:GS_RS13555
uniprot id: Q749P5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

243231:GS RS05465
gene id: 243231:GS_RS05465
uniprot id: Q74E68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

243231:GS RS08595
gene id: 243231:GS_RS08595
uniprot id: Q74CF4
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

243231:GS RS01165
gene id: 243231:GS_RS01165
uniprot id: Q74GL3
names: Similarity
messages: Belongs to the UPF0502 family.

243231:GS RS14180
gene id: 243231:GS_RS14180
uniprot id: Q749B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

243231:GS RS10725
gene id: 243231:GS_RS10725
uniprot id: Q74BA5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

243231:GS RS09000
gene id: 243231:GS_RS09000
uniprot id: Q74C79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

243231:GS RS08660
gene id: 243231:GS_RS08660
uniprot id: Q74CE1
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS09485
gene id: 243231:GS_RS09485
uniprot id: P61323
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

243231:GS RS00145
gene id: 243231:GS_RS00145
uniprot id: Q74H64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

243231:GS RS17175
gene id: 243231:GS_RS17175
uniprot id: Q746T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

243231:GS RS16020
gene id: 243231:GS_RS16020
uniprot id: Q747S2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

243231:GS RS02305
gene id: 243231:GS_RS02305
uniprot id: Q74FZ0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

243231:GS RS16775
gene id: 243231:GS_RS16775
uniprot id: Q747B9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

243231:GS RS17200
gene id: 243231:GS_RS17200
uniprot id: Q746T4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

243231:GS RS02175
gene id: 243231:GS_RS02175
uniprot id: Q74G16
names: Similarity
messages: Belongs to the GSP E family.

243231:GS RS02840
gene id: 243231:GS_RS02840
uniprot id: Q74FN5
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

243231:GS RS02885
gene id: 243231:GS_RS02885
uniprot id: Q74FM6
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

243231:GS RS15835
gene id: 243231:GS_RS15835
uniprot id: Q747W1
names: Similarity
messages: Belongs to the cytochrome c-552 family.

243231:GS RS05545
gene id: 243231:GS_RS05545
uniprot id: Q74E52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

243231:GS RS17040
gene id: 243231:GS_RS17040
uniprot id: Q746W7
names: Similarity
messages: Belongs to the leucine-binding protein family.

243231:GS RS13955
gene id: 243231:GS_RS13955
uniprot id: Q749G2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

243231:GS RS17660
gene id: 243231:GS_RS17660
uniprot id: Q747J3
names: Similarity
messages: Belongs to the UPF0751 family.

243231:GS RS11185
gene id: 243231:GS_RS11185
uniprot id: Q74AX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

243231:GS RS03680
gene id: 243231:GS_RS03680
uniprot id: Q74F70
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS04270
gene id: 243231:GS_RS04270
uniprot id: Q74EV8
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS07405
gene id: 243231:GS_RS07405
uniprot id: Q74D31
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS00150
gene id: 243231:GS_RS00150
uniprot id: Q74H63
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

243231:GS RS14140
gene id: 243231:GS_RS14140
uniprot id: Q749C4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

243231:GS RS09380
gene id: 243231:GS_RS09380
uniprot id: Q74C12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

243231:GS RS16610
gene id: 243231:GS_RS16610
uniprot id: Q747F2
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS15550
gene id: 243231:GS_RS15550
uniprot id: P60715
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

243231:GS RS00560
gene id: 243231:GS_RS00560
uniprot id: Q74GY6
names: Similarity
messages: Belongs to the ParB family.

243231:GS RS16145
gene id: 243231:GS_RS16145
uniprot id: Q747P6
names: Similarity
messages: Belongs to the peptidase S8 family.

243231:GS RS01540
gene id: 243231:GS_RS01540
uniprot id: Q74GD7
names: Similarity
messages: Belongs to the HypE family.

243231:GS RS06340
gene id: 243231:GS_RS06340
uniprot id: Q74DP3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

243231:GS RS17025
gene id: 243231:GS_RS17025
uniprot id: Q746X0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

243231:GS RS16300
gene id: 243231:GS_RS16300
uniprot id: Q747K9
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

243231:GS RS16100
gene id: 243231:GS_RS16100
uniprot id: Q747Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

243231:GS RS07185
gene id: 243231:GS_RS07185
uniprot id: Q74D73
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

243231:GS RS08690
gene id: 243231:GS_RS08690
uniprot id: Q74CD5
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

243231:GS RS15390
gene id: 243231:GS_RS15390
uniprot id: Q748D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

243231:GS RS12135
gene id: 243231:GS_RS12135
uniprot id: Q74AG2
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS12350
gene id: 243231:GS_RS12350
uniprot id: Q74B29
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

243231:GS RS14485
gene id: 243231:GS_RS14485
uniprot id: Q748X2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

243231:GS RS08050
gene id: 243231:GS_RS08050
uniprot id: Q74CQ9
names: Similarity
messages: Belongs to the Nth/MutY family.

243231:GS RS11230
gene id: 243231:GS_RS11230
uniprot id: Q74AW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

243231:GS RS15635
gene id: 243231:GS_RS15635
uniprot id: Q748A3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

243231:GS RS14455
gene id: 243231:GS_RS14455
uniprot id: P61404
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

243231:GS RS01510
gene id: 243231:GS_RS01510
uniprot id: Q74GE2
names: Similarity
messages: Belongs to the peptidase M1 family.

243231:GS RS13360
gene id: 243231:GS_RS13360
uniprot id: Q749T8
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

243231:GS RS13150
gene id: 243231:GS_RS13150
uniprot id: Q749X9
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS01310
gene id: 243231:GS_RS01310
uniprot id: Q74GI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

243231:GS RS14795
gene id: 243231:GS_RS14795
uniprot id: Q748R0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

243231:GS RS17210
gene id: 243231:GS_RS17210
uniprot id: Q746T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

243231:GS RS03335
gene id: 243231:GS_RS03335
uniprot id: Q74FE1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

243231:GS RS16475
gene id: 243231:GS_RS16475
uniprot id: Q747H5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

243231:GS RS11985
gene id: 243231:GS_RS11985
uniprot id: P61185
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

243231:GS RS06335
gene id: 243231:GS_RS06335
uniprot id: Q74DP4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

243231:GS RS16785
gene id: 243231:GS_RS16785
uniprot id: Q747B7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243231:GS RS16665
gene id: 243231:GS_RS16665
uniprot id: Q747E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

243231:GS RS17250
gene id: 243231:GS_RS17250
uniprot id: Q746S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 20 kDa subunit family.
messages: In the central section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of about 13 different subunits. Subunits NuoBCD, E, F, and G constitute the peripheral sector of the complex (By similarity).
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

243231:GS RS05345
gene id: 243231:GS_RS05345
uniprot id: Q74E93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

243231:GS RS02440
gene id: 243231:GS_RS02440
uniprot id: Q74FW4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

243231:GS RS05060
gene id: 243231:GS_RS05060
uniprot id: Q74EF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

243231:GS RS07640
gene id: 243231:GS_RS07640
uniprot id: P60542
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

243231:GS RS03220
gene id: 243231:GS_RS03220
uniprot id: Q74FF9
names: Similarity
messages: Belongs to the UPF0102 family.

243231:GS RS16095
gene id: 243231:GS_RS16095
uniprot id: Q747Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

243231:GS RS13220
gene id: 243231:GS_RS13220
uniprot id: Q749W5
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

243231:GS RS15445
gene id: 243231:GS_RS15445
uniprot id: Q748D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein.

243231:GS RS17145
gene id: 243231:GS_RS17145
uniprot id: Q746U5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

243231:GS RS15560
gene id: 243231:GS_RS15560
uniprot id: P60599
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

243231:GS RS09560
gene id: 243231:GS_RS09560
uniprot id: Q74BX8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

243231:GS RS15695
gene id: 243231:GS_RS15695
uniprot id: Q747Z1
names: Subunit
messages: Heterodimer of a large and a small subunit.

243231:GS RS10160
gene id: 243231:GS_RS10160
uniprot id: Q74BL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

243231:GS RS00705
gene id: 243231:GS_RS00705
uniprot id: Q74GV8
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS12300
gene id: 243231:GS_RS12300
uniprot id: Q74AD0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

243231:GS RS03660
gene id: 243231:GS_RS03660
uniprot id: Q74F75
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS08440
gene id: 243231:GS_RS08440
uniprot id: Q74CI1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

243231:GS RS06705
gene id: 243231:GS_RS06705
uniprot id: Q74DG9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

243231:GS RS15210
gene id: 243231:GS_RS15210
uniprot id: Q748H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

243231:GS RS00310
gene id: 243231:GS_RS00310
uniprot id: Q74H35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

243231:GS RS00760
gene id: 243231:GS_RS00760
uniprot id: Q74GU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

243231:GS RS01545
gene id: 243231:GS_RS01545
uniprot id: Q74GD6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243231:GS RS13845
gene id: 243231:GS_RS13845
uniprot id: Q749I4
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

243231:GS RS14310
gene id: 243231:GS_RS14310
uniprot id: Q748Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

243231:GS RS16530
gene id: 243231:GS_RS16530
uniprot id: Q747G5
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

243231:GS RS03455
gene id: 243231:GS_RS03455
uniprot id: Q74FB7
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

243231:GS RS01905
gene id: 243231:GS_RS01905
uniprot id: Q74G65
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

243231:GS RS11480
gene id: 243231:GS_RS11480
uniprot id: Q74AR6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

243231:GS RS01415
gene id: 243231:GS_RS01415
uniprot id: Q74GG1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

243231:GS RS00970
gene id: 243231:GS_RS00970
uniprot id: Q74GQ5
names: Subcellular Location Annotation
messages: Cytoplasm

243231:GS RS09870
gene id: 243231:GS_RS09870
uniprot id: Q74B39
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS15275
gene id: 243231:GS_RS15275
uniprot id: Q748G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

243231:GS RS01880
gene id: 243231:GS_RS01880
uniprot id: Q74G69
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

243231:GS RS14250
gene id: 243231:GS_RS14250
uniprot id: Q749A6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

243231:GS RS14150
gene id: 243231:GS_RS14150
uniprot id: Q749C2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-99 inactivates the nitrogenase reductase and regulates nitrogenase activity.

243231:GS RS13670
gene id: 243231:GS_RS13670
uniprot id: Q749M1
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

243231:GS RS13170
gene id: 243231:GS_RS13170
uniprot id: Q749X5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

243231:GS RS14990
gene id: 243231:GS_RS14990
uniprot id: Q748L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

243231:GS RS15425
gene id: 243231:GS_RS15425
uniprot id: Q748D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

243231:GS RS16930
gene id: 243231:GS_RS16930
uniprot id: P61343
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

243231:GS RS05175
gene id: 243231:GS_RS05175
uniprot id: Q74EC8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243231:GS RS02860
gene id: 243231:GS_RS02860
uniprot id: Q74FN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

243231:GS RS14490
gene id: 243231:GS_RS14490
uniprot id: Q748X1
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS02040
gene id: 243231:GS_RS02040
uniprot id: Q74G39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

243231:GS RS13855
gene id: 243231:GS_RS13855
uniprot id: Q749I2
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

243231:GS RS12495
gene id: 243231:GS_RS12495
uniprot id: Q74AA3
names: Similarity
messages: Belongs to the carbamate kinase family.

243231:GS RS14375
gene id: 243231:GS_RS14375
uniprot id: I7EPD8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

243231:GS RS09855
gene id: 243231:GS_RS09855
uniprot id: Q74BU4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

243231:GS RS12710
gene id: 243231:GS_RS12710
uniprot id: Q74A60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

243231:GS RS09155
gene id: 243231:GS_RS09155
uniprot id: Q74C50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

243231:GS RS08955
gene id: 243231:GS_RS08955
uniprot id: Q74C84
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

243231:GS RS01750
gene id: 243231:GS_RS01750
uniprot id: Q74G94
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

243231:GS RS08790
gene id: 243231:GS_RS08790
uniprot id: Q74CB4
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

243231:GS RS07955
gene id: 243231:GS_RS07955
uniprot id: P61908
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

243231:GS RS08705
gene id: 243231:GS_RS08705
uniprot id: Q74CD2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

243231:GS RS08160
gene id: 243231:GS_RS08160
uniprot id: Q74CN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

243231:GS RS04645
gene id: 243231:GS_RS04645
uniprot id: Q74EN9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

243231:GS RS06530
gene id: 243231:GS_RS06530
uniprot id: Q74DK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

243231:GS RS15130
gene id: 243231:GS_RS15130
uniprot id: Q748J3
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

243231:GS RS14275
gene id: 243231:GS_RS14275
uniprot id: Q749A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

243231:GS RS03695
gene id: 243231:GS_RS03695
uniprot id: Q74F67
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS11335
gene id: 243231:GS_RS11335
uniprot id: Q74AU2
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

243231:GS RS08745
gene id: 243231:GS_RS08745
uniprot id: P61688
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

243231:GS RS00730
gene id: 243231:GS_RS00730
uniprot id: Q74GV3
names: Similarity
messages: Belongs to the LarC family.

243231:GS RS13655
gene id: 243231:GS_RS13655
uniprot id: Q749M4
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

243231:GS RS08680
gene id: 243231:GS_RS08680
uniprot id: Q74CD7
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

243231:GS RS00570
gene id: 243231:GS_RS00570
uniprot id: Q74GY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

243231:GS RS12750
gene id: 243231:GS_RS12750
uniprot id: Q74A53
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

243231:GS RS02265
gene id: 243231:GS_RS02265
uniprot id: Q74FZ7
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

243231:GS RS12650
gene id: 243231:GS_RS12650
uniprot id: Q74A71
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

243231:GS RS13175
gene id: 243231:GS_RS13175
uniprot id: Q749X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

243231:GS RS01140
gene id: 243231:GS_RS01140
uniprot id: Q74GL9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

243231:GS RS15280
gene id: 243231:GS_RS15280
uniprot id: Q748G0
names: Similarity
messages: Belongs to the bacterial flagellin family.

243231:GS RS16215
gene id: 243231:GS_RS16215
uniprot id: Q747M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

243231:GS RS04900
gene id: 243231:GS_RS04900
uniprot id: Q74EI7
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

243231:GS RS17330
gene id: 243231:GS_RS17330
uniprot id: Q746Q7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

243231:GS RS07135
gene id: 243231:GS_RS07135
uniprot id: Q74D84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

243231:GS RS15115
gene id: 243231:GS_RS15115
uniprot id: Q748J6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

243231:GS RS02095
gene id: 243231:GS_RS02095
uniprot id: Q74G28
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

243231:GS RS08640
gene id: 243231:GS_RS08640
uniprot id: Q74CE5
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

243231:GS RS16015
gene id: 243231:GS_RS16015
uniprot id: Q747S3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

243231:GS RS05615
gene id: 243231:GS_RS05615
uniprot id: Q74E38
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

243231:GS RS01740
gene id: 243231:GS_RS01740
uniprot id: Q74G96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

243231:GS RS01495
gene id: 243231:GS_RS01495
uniprot id: Q74GE5
names: Similarity
messages: Belongs to the transglycosylase Slt family.

243231:GS RS12190
gene id: 243231:GS_RS12190
uniprot id: Q74AF1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

243231:GS RS06850
gene id: 243231:GS_RS06850
uniprot id: Q74DD9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

243231:GS RS06835
gene id: 243231:GS_RS06835
uniprot id: Q74DE2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243231:GS RS16025
gene id: 243231:GS_RS16025
uniprot id: Q747S1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

243231:GS RS05975
gene id: 243231:GS_RS05975
uniprot id: Q74DW7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

243231:GS RS02455
gene id: 243231:GS_RS02455
uniprot id: Q74FW1
names: Similarity
messages: Belongs to the DEAD box helicase family.

243231:GS RS09160
gene id: 243231:GS_RS09160
uniprot id: Q74C49
names: Similarity
messages: Belongs to the transglycosylase Slt family.

243231:GS RS14260
gene id: 243231:GS_RS14260
uniprot id: Q749A4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

243231:GS RS15610
gene id: 243231:GS_RS15610
uniprot id: Q748A8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

243231:GS RS08005
gene id: 243231:GS_RS08005
uniprot id: Q74CR8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

243231:GS RS12705
gene id: 243231:GS_RS12705
uniprot id: Q74A61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

243231:GS RS00065
gene id: 243231:GS_RS00065
uniprot id: Q74H80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

243231:GS RS11710
gene id: 243231:GS_RS11710
uniprot id: Q74AM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

243231:GS RS09095
gene id: 243231:GS_RS09095
uniprot id: Q74C63
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

243231:GS RS11790
gene id: 243231:GS_RS11790
uniprot id: Q74AK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

243231:GS RS09490
gene id: 243231:GS_RS09490
uniprot id: Q74BZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

243231:GS RS08820
gene id: 243231:GS_RS08820
uniprot id: Q74CA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

243231:GS RS02105
gene id: 243231:GS_RS02105
uniprot id: I7EEU0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

243231:GS RS03360
gene id: 243231:GS_RS03360
uniprot id: Q74FD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

243231:GS RS15070
gene id: 243231:GS_RS15070
uniprot id: P61985
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

243231:GS RS02235
gene id: 243231:GS_RS02235
uniprot id: Q74G04
names: Similarity
messages: Belongs to the peptidase M20A family.

243231:GS RS15090
gene id: 243231:GS_RS15090
uniprot id: Q748K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).

243231:GS RS16935
gene id: 243231:GS_RS16935
uniprot id: Q746Y7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

243231:GS RS16210
gene id: 243231:GS_RS16210
uniprot id: Q747N0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

243231:GS RS00580
gene id: 243231:GS_RS00580
uniprot id: Q74GY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

243231:GS RS15295
gene id: 243231:GS_RS15295
uniprot id: Q748F7
names: Similarity
messages: Belongs to the FlgM family.

243231:GS RS06860
gene id: 243231:GS_RS06860
uniprot id: Q74DD7
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

243231:GS RS14335
gene id: 243231:GS_RS14335
uniprot id: Q748Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

243231:GS RS05800
gene id: 243231:GS_RS05800
uniprot id: Q74E06
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.

243231:GS RS10420
gene id: 243231:GS_RS10420
uniprot id: Q74BG6
names: Similarity
messages: Belongs to the peptidase S8 family.

243231:GS RS07595
gene id: 243231:GS_RS07595
uniprot id: Q74CZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

243231:GS RS05225
gene id: 243231:GS_RS05225
uniprot id: Q74EB7
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS16925
gene id: 243231:GS_RS16925
uniprot id: Q746Y8
names: Function
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

243231:GS RS09045
gene id: 243231:GS_RS09045
uniprot id: Q3V8C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

243231:GS RS00485
gene id: 243231:GS_RS00485
uniprot id: Q74H00
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS00595
gene id: 243231:GS_RS00595
uniprot id: Q74GX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

243231:GS RS14540
gene id: 243231:GS_RS14540
uniprot id: Q748W1
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS08150
gene id: 243231:GS_RS08150
uniprot id: Q74CP1
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

243231:GS RS11950
gene id: 243231:GS_RS11950
uniprot id: Q74AH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

243231:GS RS10460
gene id: 243231:GS_RS10460
uniprot id: Q74BF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

243231:GS RS09585
gene id: 243231:GS_RS09585
uniprot id: Q74BX3
names: Subcellular Location Annotation
messages: Cytoplasm

243231:GS RS00185
gene id: 243231:GS_RS00185
uniprot id: Q74H56
names: Similarity
messages: Belongs to the CapA family.

243231:GS RS08575
gene id: 243231:GS_RS08575
uniprot id: Q74CF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

243231:GS RS05790
gene id: 243231:GS_RS05790
uniprot id: Q74E08
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

243231:GS RS11190
gene id: 243231:GS_RS11190
uniprot id: Q74AX0
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

243231:GS RS03880
gene id: 243231:GS_RS03880
uniprot id: Q74F36
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS01295
gene id: 243231:GS_RS01295
uniprot id: Q74GI6
names: Similarity
messages: Belongs to the universal stress protein A family.

243231:GS RS12795
gene id: 243231:GS_RS12795
uniprot id: Q74A44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

243231:GS RS00690
gene id: 243231:GS_RS00690
uniprot id: Q74GW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

243231:GS RS07570
gene id: 243231:GS_RS07570
uniprot id: Q74D00
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

243231:GS RS04485
gene id: 243231:GS_RS04485
uniprot id: Q74ER6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

243231:GS RS01105
gene id: 243231:GS_RS01105
uniprot id: Q74GM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

243231:GS RS06460
gene id: 243231:GS_RS06460
uniprot id: Q74DL9
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

243231:GS RS04040
gene id: 243231:GS_RS04040
uniprot id: Q74F06
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

243231:GS RS02445
gene id: 243231:GS_RS02445
uniprot id: Q74FW3
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

243231:GS RS14840
gene id: 243231:GS_RS14840
uniprot id: Q748Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

243231:GS RS13650
gene id: 243231:GS_RS13650
uniprot id: Q749M5
names: Similarity
messages: Belongs to the peptidase A31 family.

243231:GS RS11375
gene id: 243231:GS_RS11375
uniprot id: Q74AT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

243231:GS RS07810
gene id: 243231:GS_RS07810
uniprot id: Q74CV4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

243231:GS RS02495
gene id: 243231:GS_RS02495
uniprot id: Q74FV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

243231:GS RS04620
gene id: 243231:GS_RS04620
uniprot id: Q74EP4
names: Similarity
messages: Belongs to the AdoMet synthetase 2 family.

243231:GS RS16270
gene id: 243231:GS_RS16270
uniprot id: Q747L5
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

243231:GS RS07365
gene id: 243231:GS_RS07365
uniprot id: Q74D39
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS07420
gene id: 243231:GS_RS07420
uniprot id: Q74D28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

243231:GS RS12765
gene id: 243231:GS_RS12765
uniprot id: Q74A50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

243231:GS RS07990
gene id: 243231:GS_RS07990
uniprot id: Q74CS1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

243231:GS RS04555
gene id: 243231:GS_RS04555
uniprot id: I7FIC4
names: Subcellular Location Annotation
messages: Cytoplasm

243231:GS RS12600
gene id: 243231:GS_RS12600
uniprot id: Q74A82
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS15575
gene id: 243231:GS_RS15575
uniprot id: P60859
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

243231:GS RS16435
gene id: 243231:GS_RS16435
uniprot id: Q747I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

243231:GS RS05770
gene id: 243231:GS_RS05770
uniprot id: Q74E12
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS14285
gene id: 243231:GS_RS14285
uniprot id: Q748Z9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

243231:GS RS02255
gene id: 243231:GS_RS02255
uniprot id: Q74FZ9
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

243231:GS RS16595
gene id: 243231:GS_RS16595
uniprot id: Q747F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

243231:GS RS04840
gene id: 243231:GS_RS04840
uniprot id: Q74EK0
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS02620
gene id: 243231:GS_RS02620
uniprot id: Q74FT1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

243231:GS RS03950
gene id: 243231:GS_RS03950
uniprot id: Q74F23
names: Similarity
messages: Belongs to the peptidase A31 family.

243231:GS RS15255
gene id: 243231:GS_RS15255
uniprot id: Q748G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

243231:GS RS11380
gene id: 243231:GS_RS11380
uniprot id: Q74AT4
names: Similarity
messages: Belongs to the Skp family.

243231:GS RS16735
gene id: 243231:GS_RS16735
uniprot id: Q747C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

243231:GS RS13860
gene id: 243231:GS_RS13860
uniprot id: Q749I1
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

243231:GS RS09110
gene id: 243231:GS_RS09110
uniprot id: Q74C59
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

243231:GS RS14715
gene id: 243231:GS_RS14715
uniprot id: Q748S6
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

243231:GS RS13230
gene id: 243231:GS_RS13230
uniprot id: Q749W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

243231:GS RS04870
gene id: 243231:GS_RS04870
uniprot id: Q74EJ3
names: Similarity
messages: Belongs to the peptidase S41A family.

243231:GS RS01535
gene id: 243231:GS_RS01535
uniprot id: Q74GD8
names: Similarity
messages: Belongs to the HypD family.

243231:GS RS11370
gene id: 243231:GS_RS11370
uniprot id: P61453
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

243231:GS RS09035
gene id: 243231:GS_RS09035
uniprot id: Q74C72
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

243231:GS RS02075
gene id: 243231:GS_RS02075
uniprot id: Q74G32
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

243231:GS RS00740
gene id: 243231:GS_RS00740
uniprot id: Q74GV1
names: Similarity
messages: Belongs to the CinA family.

243231:GS RS14980
gene id: 243231:GS_RS14980
uniprot id: Q748M1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

243231:GS RS06980
gene id: 243231:GS_RS06980
uniprot id: Q74DB4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

243231:GS RS02125
gene id: 243231:GS_RS02125
uniprot id: Q3V8D0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

243231:GS RS01690
gene id: 243231:GS_RS01690
uniprot id: Q74GA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

243231:GS RS12595
gene id: 243231:GS_RS12595
uniprot id: Q74A83
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS01685
gene id: 243231:GS_RS01685
uniprot id: Q74GA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

243231:GS RS01600
gene id: 243231:GS_RS01600
uniprot id: Q74GC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

243231:GS RS09210
gene id: 243231:GS_RS09210
uniprot id: Q74C39
names: Similarity
messages: Belongs to the P(II) protein family.

243231:GS RS07370
gene id: 243231:GS_RS07370
uniprot id: Q74D38
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

243231:GS RS02460
gene id: 243231:GS_RS02460
uniprot id: Q74FW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

243231:GS RS11885
gene id: 243231:GS_RS11885
uniprot id: Q74AI4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

243231:GS RS08065
gene id: 243231:GS_RS08065
uniprot id: Q74CQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

243231:GS RS02570
gene id: 243231:GS_RS02570
uniprot id: Q74FU0
names: Similarity
messages: Belongs to the universal stress protein A family.

243231:GS RS08240
gene id: 243231:GS_RS08240
uniprot id: Q74CM2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

243231:GS RS07910
gene id: 243231:GS_RS07910
uniprot id: Q74CT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

243231:GS RS07130
gene id: 243231:GS_RS07130
uniprot id: Q74D85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

243231:GS RS09740
gene id: 243231:GS_RS09740
uniprot id: Q74BU0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

243231:GS RS01810
gene id: 243231:GS_RS01810
uniprot id: Q74G83
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

243231:GS RS16335
gene id: 243231:GS_RS16335
uniprot id: Q747K1
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS09165
gene id: 243231:GS_RS09165
uniprot id: Q74C48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

243231:GS RS11275
gene id: 243231:GS_RS11275
uniprot id: Q74AV4
names: Similarity
messages: Belongs to the polysaccharide synthase family.

243231:GS RS12230
gene id: 243231:GS_RS12230
uniprot id: Q74AE3
names: Similarity
messages: Belongs to the peptidase S16 family.

243231:GS RS00640
gene id: 243231:GS_RS00640
uniprot id: Q74GX1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.
messages: Periplasm

243231:GS RS03530
gene id: 243231:GS_RS03530
uniprot id: Q74FA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

243231:GS RS08140
gene id: 243231:GS_RS08140
uniprot id: Q74CP3
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS03955
gene id: 243231:GS_RS03955
uniprot id: Q74F22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

243231:GS RS10495
gene id: 243231:GS_RS10495
uniprot id: Q74BF0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

243231:GS RS12235
gene id: 243231:GS_RS12235
uniprot id: Q74AE2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

243231:GS RS10295
gene id: 243231:GS_RS10295
uniprot id: P62061
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e. capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

243231:GS RS12105
gene id: 243231:GS_RS12105
uniprot id: Q74B03
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

243231:GS RS03215
gene id: 243231:GS_RS03215
uniprot id: Q74FG0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

243231:GS RS07250
gene id: 243231:GS_RS07250
uniprot id: Q74D60
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

243231:GS RS15405
gene id: 243231:GS_RS15405
uniprot id: P61679
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

243231:GS RS16115
gene id: 243231:GS_RS16115
uniprot id: Q747Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

243231:GS RS08015
gene id: 243231:GS_RS08015
uniprot id: Q74CR6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

243231:GS RS13580
gene id: 243231:GS_RS13580
uniprot id: Q749P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

243231:GS RS03050
gene id: 243231:GS_RS03050
uniprot id: Q74FJ5
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS16105
gene id: 243231:GS_RS16105
uniprot id: Q747Q5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

243231:GS RS06710
gene id: 243231:GS_RS06710
uniprot id: Q74DG8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

243231:GS RS05805
gene id: 243231:GS_RS05805
uniprot id: Q74E05
names: Similarity
messages: Belongs to the peptidase C56 family.

243231:GS RS00170
gene id: 243231:GS_RS00170
uniprot id: Q74H59
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

243231:GS RS13155
gene id: 243231:GS_RS13155
uniprot id: Q749X8
names: Similarity
messages: Belongs to the RecJ family.

243231:GS RS16945
gene id: 243231:GS_RS16945
uniprot id: Q746Y5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

243231:GS RS10545
gene id: 243231:GS_RS10545
uniprot id: Q74BE1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

243231:GS RS03600
gene id: 243231:GS_RS03600
uniprot id: Q74F88
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

243231:GS RS14005
gene id: 243231:GS_RS14005
uniprot id: Q749F2
names: Similarity
messages: Belongs to the UPF0145 family.

243231:GS RS10455
gene id: 243231:GS_RS10455
uniprot id: Q74BF8
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

243231:GS RS00025
gene id: 243231:GS_RS00025
uniprot id: Q74H88
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

243231:GS RS16295
gene id: 243231:GS_RS16295
uniprot id: Q747L0
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

243231:GS RS11170
gene id: 243231:GS_RS11170
uniprot id: Q74AX4
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

243231:GS RS11935
gene id: 243231:GS_RS11935
uniprot id: Q74AH5
names: Similarity
messages: Belongs to the TrpC family.

243231:GS RS01050
gene id: 243231:GS_RS01050
uniprot id: Q74GN9
names: Subcellular Location Annotation
messages: Cytoplasm

243231:GS RS13095
gene id: 243231:GS_RS13095
uniprot id: Q749Y9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

243231:GS RS00815
gene id: 243231:GS_RS00815
uniprot id: Q74GT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

243231:GS RS12675
gene id: 243231:GS_RS12675
uniprot id: Q74A67
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

243231:GS RS07165
gene id: 243231:GS_RS07165
uniprot id: Q74D77
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

243231:GS RS14385
gene id: 243231:GS_RS14385
uniprot id: Q748Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

243231:GS RS15570
gene id: 243231:GS_RS15570
uniprot id: P61000
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

243231:GS RS14145
gene id: 243231:GS_RS14145
uniprot id: Q749C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

243231:GS RS13610
gene id: 243231:GS_RS13610
uniprot id: Q749N5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

243231:GS RS08105
gene id: 243231:GS_RS08105
uniprot id: Q74CP9
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

243231:GS RS01110
gene id: 243231:GS_RS01110
uniprot id: Q74GM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

243231:GS RS00670
gene id: 243231:GS_RS00670
uniprot id: Q74GW5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

243231:GS RS04355
gene id: 243231:GS_RS04355
uniprot id: Q74EU1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

243231:GS RS10385
gene id: 243231:GS_RS10385
uniprot id: Q74BH3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243231:GS RS09140
gene id: 243231:GS_RS09140
uniprot id: P61667
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

243231:GS RS07925
gene id: 243231:GS_RS07925
uniprot id: Q74CT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

243231:GS RS09180
gene id: 243231:GS_RS09180
uniprot id: Q74C45
names: Similarity
messages: Belongs to the MEMO1 family.

243231:GS RS08865
gene id: 243231:GS_RS08865
uniprot id: Q74C99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

243231:GS RS11750
gene id: 243231:GS_RS11750
uniprot id: Q74AL1
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS12430
gene id: 243231:GS_RS12430
uniprot id: Q74AB8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

243231:GS RS13645
gene id: 243231:GS_RS13645
uniprot id: P61664
names: Similarity
messages: Belongs to the SfsA family.

243231:GS RS07430
gene id: 243231:GS_RS07430
uniprot id: Q74D26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

243231:GS RS09310
gene id: 243231:GS_RS09310
uniprot id: Q74C21
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

243231:GS RS17180
gene id: 243231:GS_RS17180
uniprot id: Q746T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

243231:GS RS08485
gene id: 243231:GS_RS08485
uniprot id: Q74CH3
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

243231:GS RS05395
gene id: 243231:GS_RS05395
uniprot id: Q74E83
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

243231:GS RS07895
gene id: 243231:GS_RS07895
uniprot id: Q74CT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243231:GS RS09590
gene id: 243231:GS_RS09590
uniprot id: Q74BX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

243231:GS RS08500
gene id: 243231:GS_RS08500
uniprot id: Q74CH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243231:GS RS14215
gene id: 243231:GS_RS14215
uniprot id: Q749B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

243231:GS RS01340
gene id: 243231:GS_RS01340
uniprot id: Q74GH6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

243231:GS RS07180
gene id: 243231:GS_RS07180
uniprot id: Q74D74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

243231:GS RS16895
gene id: 243231:GS_RS16895
uniprot id: Q746Z4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

243231:GS RS00565
gene id: 243231:GS_RS00565
uniprot id: Q74GY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

243231:GS RS10050
gene id: 243231:GS_RS10050
uniprot id: Q74BP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

243231:GS RS15340
gene id: 243231:GS_RS15340
uniprot id: Q3V8C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

243231:GS RS03200
gene id: 243231:GS_RS03200
uniprot id: Q74FG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

243231:GS RS16345
gene id: 243231:GS_RS16345
uniprot id: Q747J9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

243231:GS RS10325
gene id: 243231:GS_RS10325
uniprot id: Q74BI5
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS05325
gene id: 243231:GS_RS05325
uniprot id: Q74E97
names: Similarity
messages: Belongs to the PilY1 family.

243231:GS RS07375
gene id: 243231:GS_RS07375
uniprot id: Q74D37
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

243231:GS RS05835
gene id: 243231:GS_RS05835
uniprot id: Q74DZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

243231:GS RS03300
gene id: 243231:GS_RS03300
uniprot id: Q74FE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

243231:GS RS09630
gene id: 243231:GS_RS09630
uniprot id: Q74BW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

243231:GS RS16860
gene id: 243231:GS_RS16860
uniprot id: Q747A1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

243231:GS RS11585
gene id: 243231:GS_RS11585
uniprot id: Q74AP4
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

243231:GS RS13350
gene id: 243231:GS_RS13350
uniprot id: Q749U0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243231:GS RS13120
gene id: 243231:GS_RS13120
uniprot id: Q749Y4
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

243231:GS RS14425
gene id: 243231:GS_RS14425
uniprot id: Q748X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

243231:GS RS02595
gene id: 243231:GS_RS02595
uniprot id: P60347
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

243231:GS RS15270
gene id: 243231:GS_RS15270
uniprot id: Q748G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

243231:GS RS11600
gene id: 243231:GS_RS11600
uniprot id: Q74AP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

243231:GS RS02085
gene id: 243231:GS_RS02085
uniprot id: Q74G30
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

243231:GS RS05290
gene id: 243231:GS_RS05290
uniprot id: Q74EA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

243231:GS RS02585
gene id: 243231:GS_RS02585
uniprot id: Q74FT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

243231:GS RS15875
gene id: 243231:GS_RS15875
uniprot id: Q747V3
names: Similarity
messages: Belongs to the threonine aldolase family.

243231:GS RS14695
gene id: 243231:GS_RS14695
uniprot id: Q748T0
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

243231:GS RS17065
gene id: 243231:GS_RS17065
uniprot id: Q746W2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

243231:GS RS15125
gene id: 243231:GS_RS15125
uniprot id: Q748J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

243231:GS RS15990
gene id: 243231:GS_RS15990
uniprot id: Q747S8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

243231:GS RS06615
gene id: 243231:GS_RS06615
uniprot id: Q74DI7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

243231:GS RS06360
gene id: 243231:GS_RS06360
uniprot id: Q74DN9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

243231:GS RS14350
gene id: 243231:GS_RS14350
uniprot id: Q748Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

243231:GS RS05480
gene id: 243231:GS_RS05480
uniprot id: Q74E65
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

243231:GS RS10975
gene id: 243231:GS_RS10975
uniprot id: Q74B56
names: Similarity
messages: Belongs to the FlgM family.

243231:GS RS14470
gene id: 243231:GS_RS14470
uniprot id: Q748X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

243231:GS RS08635
gene id: 243231:GS_RS08635
uniprot id: Q74CE6
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

243231:GS RS06560
gene id: 243231:GS_RS06560
uniprot id: Q74DJ9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

243231:GS RS09020
gene id: 243231:GS_RS09020
uniprot id: Q74C75
names: Similarity
messages: Belongs to the aspartokinase family.

243231:GS RS08125
gene id: 243231:GS_RS08125
uniprot id: I7EP62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

243231:GS RS05935
gene id: 243231:GS_RS05935
uniprot id: Q74DX6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

243231:GS RS09125
gene id: 243231:GS_RS09125
uniprot id: Q74C56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

243231:GS RS07125
gene id: 243231:GS_RS07125
uniprot id: Q74D86
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

243231:GS RS12510
gene id: 243231:GS_RS12510
uniprot id: Q74AA0
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS10720
gene id: 243231:GS_RS10720
uniprot id: Q74BA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

243231:GS RS11005
gene id: 243231:GS_RS11005
uniprot id: Q74B50
names: Similarity
messages: Belongs to the AOR/FOR family.

243231:GS RS08070
gene id: 243231:GS_RS08070
uniprot id: P61609
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

243231:GS RS01135
gene id: 243231:GS_RS01135
uniprot id: Q74GM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

243231:GS RS15640
gene id: 243231:GS_RS15640
uniprot id: Q748A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

243231:GS RS07875
gene id: 243231:GS_RS07875
uniprot id: Q74CU2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

243231:GS RS00225
gene id: 243231:GS_RS00225
uniprot id: P61608
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

243231:GS RS00190
gene id: 243231:GS_RS00190
uniprot id: Q74H55
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

243231:GS RS04715
gene id: 243231:GS_RS04715
uniprot id: Q74EM5
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

243231:GS RS08785
gene id: 243231:GS_RS08785
uniprot id: Q74CB5
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

243231:GS RS09575
gene id: 243231:GS_RS09575
uniprot id: Q74BX5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

243231:GS RS08010
gene id: 243231:GS_RS08010
uniprot id: Q74CR7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

243231:GS RS11940
gene id: 243231:GS_RS11940
uniprot id: Q74AH4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

243231:GS RS14355
gene id: 243231:GS_RS14355
uniprot id: Q748X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

243231:GS RS05385
gene id: 243231:GS_RS05385
uniprot id: Q74E86
names: Similarity
messages: Belongs to the DnaA family.

243231:GS RS01995
gene id: 243231:GS_RS01995
uniprot id: Q74G48
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243231:GS RS05005
gene id: 243231:GS_RS05005
uniprot id: Q74EG4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

243231:GS RS09620
gene id: 243231:GS_RS09620
uniprot id: Q74BW7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

243231:GS RS09070
gene id: 243231:GS_RS09070
uniprot id: Q74C66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

243231:GS RS15110
gene id: 243231:GS_RS15110
uniprot id: P61425
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family. 5-hydroxybenzimidazole synthase subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of aminoimidazole ribotide (AIR) to 5-hydroxybenzimidazole (5-HBI) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Is thus involved in the anaerobic biosynthesis of the benzimidazole lower axial ligand of the cobamide produced by G.sulfurreducens.
messages: Homodimer.

243231:GS RS11560
gene id: 243231:GS_RS11560
uniprot id: Q74AP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

243231:GS RS16090
gene id: 243231:GS_RS16090
uniprot id: Q747Q8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

243231:GS RS08515
gene id: 243231:GS_RS08515
uniprot id: Q74CG7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

243231:GS RS01155
gene id: 243231:GS_RS01155
uniprot id: Q74GL6
names: Similarity
messages: Belongs to the GSP E family.

243231:GS RS16450
gene id: 243231:GS_RS16450
uniprot id: Q747I0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

243231:GS RS14735
gene id: 243231:GS_RS14735
uniprot id: Q748S2
names: Similarity
messages: Belongs to the hemerythrin family.

243231:GS RS14895
gene id: 243231:GS_RS14895
uniprot id: Q748P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

243231:GS RS00505
gene id: 243231:GS_RS00505
uniprot id: Q74GZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

243231:GS RS15945
gene id: 243231:GS_RS15945
uniprot id: Q747T8
names: Similarity
messages: Belongs to the VgrG protein family.

243231:GS RS09105
gene id: 243231:GS_RS09105
uniprot id: Q74C60
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

243231:GS RS15540
gene id: 243231:GS_RS15540
uniprot id: Q748B4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

243231:GS RS15655
gene id: 243231:GS_RS15655
uniprot id: Q747Z9
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

243231:GS RS06075
gene id: 243231:GS_RS06075
uniprot id: Q74DU6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

243231:GS RS13180
gene id: 243231:GS_RS13180
uniprot id: Q749X3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

243231:GS RS04770
gene id: 243231:GS_RS04770
uniprot id: Q74EL4
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS08995
gene id: 243231:GS_RS08995
uniprot id: Q74C80
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

243231:GS RS09615
gene id: 243231:GS_RS09615
uniprot id: Q3V8C8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

243231:GS RS01370
gene id: 243231:GS_RS01370
uniprot id: Q74GH0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

243231:GS RS00220
gene id: 243231:GS_RS00220
uniprot id: Q74H52
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

243231:GS RS09465
gene id: 243231:GS_RS09465
uniprot id: Q74BZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

243231:GS RS08970
gene id: 243231:GS_RS08970
uniprot id: Q74C81
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

243231:GS RS08965
gene id: 243231:GS_RS08965
uniprot id: Q74C82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

243231:GS RS07065
gene id: 243231:GS_RS07065
uniprot id: Q74D97
names: Similarity
messages: Belongs to the TlyA family.

243231:GS RS15750
gene id: 243231:GS_RS15750
uniprot id: Q747X9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

243231:GS RS11365
gene id: 243231:GS_RS11365
uniprot id: Q74AT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

243231:GS RS06085
gene id: 243231:GS_RS06085
uniprot id: Q74DU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

243231:GS RS05265
gene id: 243231:GS_RS05265
uniprot id: Q74EA9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

243231:GS RS08670
gene id: 243231:GS_RS08670
uniprot id: Q74CD9
names: Similarity
messages: Belongs to the leucine-binding protein family.

243231:GS RS00585
gene id: 243231:GS_RS00585
uniprot id: Q74GY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

243231:GS RS02895
gene id: 243231:GS_RS02895
uniprot id: Q74FM4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243231:GS RS08175
gene id: 243231:GS_RS08175
uniprot id: Q74CN6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243231:GS RS09535
gene id: 243231:GS_RS09535
uniprot id: Q74BY3
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

243231:GS RS11675
gene id: 243231:GS_RS11675
uniprot id: Q74AM6
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

243231:GS RS10265
gene id: 243231:GS_RS10265
uniprot id: Q74BJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

243231:GS RS08600
gene id: 243231:GS_RS08600
uniprot id: Q74CF3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.

243231:GS RS09495
gene id: 243231:GS_RS09495
uniprot id: Q74BZ1
names: Similarity
messages: Belongs to the sigma-54 factor family.

243231:GS RS11980
gene id: 243231:GS_RS11980
uniprot id: Q74AG6
names: Similarity
messages: Belongs to the leucine-binding protein family.

243231:GS RS14625
gene id: 243231:GS_RS14625
uniprot id: Q748U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

243231:GS RS15805
gene id: 243231:GS_RS15805
uniprot id: Q747W8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

243231:GS RS08280
gene id: 243231:GS_RS08280
uniprot id: P60915
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

243231:GS RS13105
gene id: 243231:GS_RS13105
uniprot id: Q749Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

243231:GS RS14480
gene id: 243231:GS_RS14480
uniprot id: Q748X3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243231:GS RS06060
gene id: 243231:GS_RS06060
uniprot id: Q74DV0
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS11345
gene id: 243231:GS_RS11345
uniprot id: Q74AU0
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS12255
gene id: 243231:GS_RS12255
uniprot id: Q74AD8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

243231:GS RS01735
gene id: 243231:GS_RS01735
uniprot id: Q74G97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Membrane

243231:GS RS07490
gene id: 243231:GS_RS07490
uniprot id: Q74D14
names: Similarity
messages: Belongs to the ABC transporter superfamily.

243231:GS RS08825
gene id: 243231:GS_RS08825
uniprot id: Q74CA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

243231:GS RS16250
gene id: 243231:GS_RS16250
uniprot id: Q747M0
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

243231:GS RS05485
gene id: 243231:GS_RS05485
uniprot id: Q74E64
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS06975
gene id: 243231:GS_RS06975
uniprot id: Q74DB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

243231:GS RS17220
gene id: 243231:GS_RS17220
uniprot id: Q746T0
names: Similarity
messages: Belongs to the YjdM family.

243231:GS RS04010
gene id: 243231:GS_RS04010
uniprot id: Q74F12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

243231:GS RS16195
gene id: 243231:GS_RS16195
uniprot id: Q747N5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

243231:GS RS02230
gene id: 243231:GS_RS02230
uniprot id: Q74G05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

243231:GS RS05675
gene id: 243231:GS_RS05675
uniprot id: Q74E25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

243231:GS RS08605
gene id: 243231:GS_RS08605
uniprot id: Q74CF2
names: Similarity
messages: Belongs to the creatininase superfamily.

243231:GS RS02240
gene id: 243231:GS_RS02240
uniprot id: Q74G02
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

243231:GS RS08345
gene id: 243231:GS_RS08345
uniprot id: Q74CK1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

243231:GS RS07415
gene id: 243231:GS_RS07415
uniprot id: Q74D29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

243231:GS RS11800
gene id: 243231:GS_RS11800
uniprot id: Q74AK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

243231:GS RS14545
gene id: 243231:GS_RS14545
uniprot id: Q748W0
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS08860
gene id: 243231:GS_RS08860
uniprot id: Q74CA0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane

243231:GS RS01580
gene id: 243231:GS_RS01580
uniprot id: Q74GC8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

243231:GS RS11740
gene id: 243231:GS_RS11740
uniprot id: Q74AL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

243231:GS RS16425
gene id: 243231:GS_RS16425
uniprot id: Q747I5
names: Similarity
messages: Belongs to the thioredoxin family.

243231:GS RS15035
gene id: 243231:GS_RS15035
uniprot id: Q748L1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

243231:GS RS14095
gene id: 243231:GS_RS14095
uniprot id: Q749D4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

243231:GS RS00755
gene id: 243231:GS_RS00755
uniprot id: Q74GU8
names: Similarity
messages: Belongs to the GSP E family.

243231:GS RS11715
gene id: 243231:GS_RS11715
uniprot id: Q74AL8
names: Similarity
messages: Belongs to the universal stress protein A family.

243231:GS RS15215
gene id: 243231:GS_RS15215
uniprot id: Q748H4
names: Similarity
messages: Belongs to the MotB family.

243231:GS RS07425
gene id: 243231:GS_RS07425
uniprot id: Q74D27
names: Similarity
messages: Belongs to the GSP E family.

243231:GS RS16120
gene id: 243231:GS_RS16120
uniprot id: Q747Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

243231:GS RS14965
gene id: 243231:GS_RS14965
uniprot id: Q748M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

243231:GS RS09130
gene id: 243231:GS_RS09130
uniprot id: Q74C55
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

243231:GS RS10300
gene id: 243231:GS_RS10300
uniprot id: Q74BJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

243231:GS RS11115
gene id: 243231:GS_RS11115
uniprot id: P62640
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

243231:GS RS05990
gene id: 243231:GS_RS05990
uniprot id: Q74DW4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

243231:GS RS02685
gene id: 243231:GS_RS02685
uniprot id: Q74FR8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

243231:GS RS13595
gene id: 243231:GS_RS13595
uniprot id: Q749N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

243231:GS RS05540
gene id: 243231:GS_RS05540
uniprot id: Q74E53
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

243231:GS RS01715
gene id: 243231:GS_RS01715
uniprot id: Q74GA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

243231:GS RS00775
gene id: 243231:GS_RS00775
uniprot id: Q74GU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

243231:GS RS11620
gene id: 243231:GS_RS11620
uniprot id: Q74AN7
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS15010
gene id: 243231:GS_RS15010
uniprot id: Q748L5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

243231:GS RS08960
gene id: 243231:GS_RS08960
uniprot id: Q74C83
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

243231:GS RS07735
gene id: 243231:GS_RS07735
uniprot id: Q74CX1
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

243231:GS RS08190
gene id: 243231:GS_RS08190
uniprot id: Q74CN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

243231:GS RS10275
gene id: 243231:GS_RS10275
uniprot id: Q74BJ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

243231:GS RS03890
gene id: 243231:GS_RS03890
uniprot id: Q74F34
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS02900
gene id: 243231:GS_RS02900
uniprot id: Q74FM3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243231:GS RS02870
gene id: 243231:GS_RS02870
uniprot id: Q74FM9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

243231:GS RS07950
gene id: 243231:GS_RS07950
uniprot id: Q74CS8
names: Similarity
messages: Belongs to the peptidase M16 family.

243231:GS RS07100
gene id: 243231:GS_RS07100
uniprot id: Q74D91
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

243231:GS RS17005
gene id: 243231:GS_RS17005
uniprot id: Q746X4
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS03035
gene id: 243231:GS_RS03035
uniprot id: Q74FJ8
names: Similarity
messages: Belongs to the GARS family.

243231:GS RS04155
gene id: 243231:GS_RS04155
uniprot id: Q74EY4
names: Similarity
messages: Belongs to the pirin family.

243231:GS RS07400
gene id: 243231:GS_RS07400
uniprot id: Q74D32
names: Similarity
messages: Belongs to the ribF family.

243231:GS RS00675
gene id: 243231:GS_RS00675
uniprot id: Q74GW4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

243231:GS RS10640
gene id: 243231:GS_RS10640
uniprot id: Q74BC1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

243231:GS RS17365
gene id: 243231:GS_RS17365
uniprot id: I7EPF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

243231:GS RS05830
gene id: 243231:GS_RS05830
uniprot id: Q74E00
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS07350
gene id: 243231:GS_RS07350
uniprot id: Q74D42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

243231:GS RS11890
gene id: 243231:GS_RS11890
uniprot id: Q74AI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

243231:GS RS02320
gene id: 243231:GS_RS02320
uniprot id: Q74FY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

243231:GS RS10140
gene id: 243231:GS_RS10140
uniprot id: Q74BM3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

243231:GS RS17035
gene id: 243231:GS_RS17035
uniprot id: Q746W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

243231:GS RS13740
gene id: 243231:GS_RS13740
uniprot id: Q749K5
names: Function
names: Induction
names: PTM
names: Subcellular Location Annotation
messages: Binds 12 heme c groups per subunit.
messages: Cell outer membrane
messages: Involved in anaerobic respiration with Fe(3+) as terminal electron acceptor. Acts as an electron-transport mediator in the dissimilatory reduction of Fe(3+).
messages: Up-regulated by Fe(3+).

243231:GS RS08880
gene id: 243231:GS_RS08880
uniprot id: Q74C96
names: Similarity
messages: Belongs to the bacterial secretin family.

243231:GS RS02015
gene id: 243231:GS_RS02015
uniprot id: Q74G44
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243231:GS RS16110
gene id: 243231:GS_RS16110
uniprot id: Q747Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

243231:GS RS11910
gene id: 243231:GS_RS11910
uniprot id: Q6F2B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

243231:GS RS13340
gene id: 243231:GS_RS13340
uniprot id: Q749U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

243231:GS RS15410
gene id: 243231:GS_RS15410
uniprot id: Q748D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

243231:GS RS05155
gene id: 243231:GS_RS05155
uniprot id: Q74ED2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

243231:GS RS10365
gene id: 243231:GS_RS10365
uniprot id: Q74BH7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

243231:GS RS14080
gene id: 243231:GS_RS14080
uniprot id: Q749D7
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

243231:GS RS03180
gene id: 243231:GS_RS03180
uniprot id: Q74FG7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

243231:GS RS17225
gene id: 243231:GS_RS17225
uniprot id: Q746S9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

243231:GS RS16955
gene id: 243231:GS_RS16955
uniprot id: Q746Y3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

243231:GS RS02420
gene id: 243231:GS_RS02420
uniprot id: Q74FW8
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

243231:GS RS02270
gene id: 243231:GS_RS02270
uniprot id: Q74FZ6
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS00160
gene id: 243231:GS_RS00160
uniprot id: Q74H61
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

243231:GS RS06445
gene id: 243231:GS_RS06445
uniprot id: Q74DM2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243231:GS RS11350
gene id: 243231:GS_RS11350
uniprot id: Q74AT9
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

243231:GS RS17370
gene id: 243231:GS_RS17370
uniprot id: I7FKI1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

243231:GS RS03005
gene id: 243231:GS_RS03005
uniprot id: Q74FK3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

243231:GS RS06665
gene id: 243231:GS_RS06665
uniprot id: Q74DH6
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS03845
gene id: 243231:GS_RS03845
uniprot id: Q74F41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

243231:GS RS00715
gene id: 243231:GS_RS00715
uniprot id: Q74GV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

243231:GS RS17090
gene id: 243231:GS_RS17090
uniprot id: Q746V7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

243231:GS RS11225
gene id: 243231:GS_RS11225
uniprot id: Q74AW3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

243231:GS RS10175
gene id: 243231:GS_RS10175
uniprot id: Q74BL6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

243231:GS RS11570
gene id: 243231:GS_RS11570
uniprot id: Q74AP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

243231:GS RS04005
gene id: 243231:GS_RS04005
uniprot id: Q74F13
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

243231:GS RS02545
gene id: 243231:GS_RS02545
uniprot id: Q74FU5
names: Caution
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: Cytoplasm
messages: Heterotetramer with 2 alpha subunits.
messages: May catalyze the NADPH oxidation in the SfrAB NADPH-Fe(3+) oxidoreductase enzymatic complex. Probably involved in acetate metabolism and not in the reduction of Fe(3+) chelates. May serve as a major route for NADP regeneration.
messages: PubMed:17906154 suggests that SfrAB is involved in acetate metabolism and does not participate directly in the reduction of Fe(3+) chelates, as was initially proposed in PubMed:11443080.

243231:GS RS01115
gene id: 243231:GS_RS01115
uniprot id: Q74GM5
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS02170
gene id: 243231:GS_RS02170
uniprot id: Q74G17
names: Similarity
messages: Belongs to the GSP E family.

243231:GS RS15430
gene id: 243231:GS_RS15430
uniprot id: I7F9Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

243231:GS RS05490
gene id: 243231:GS_RS05490
uniprot id: Q74E63
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

243231:GS RS00830
gene id: 243231:GS_RS00830
uniprot id: Q74GT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

243231:GS RS12920
gene id: 243231:GS_RS12920
uniprot id: Q74A19
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

243231:GS RS10180
gene id: 243231:GS_RS10180
uniprot id: Q74BL5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

243231:GS RS16900
gene id: 243231:GS_RS16900
uniprot id: Q746Z3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

243231:GS RS04705
gene id: 243231:GS_RS04705
uniprot id: Q74EM7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243231:GS RS03910
gene id: 243231:GS_RS03910
uniprot id: Q74F30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

243231:GS RS01950
gene id: 243231:GS_RS01950
uniprot id: Q74G57
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

243231:GS RS04095
gene id: 243231:GS_RS04095
uniprot id: Q74EZ5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

243231:GS RS05205
gene id: 243231:GS_RS05205
uniprot id: Q74EC1
names: Similarity
messages: Belongs to the hemerythrin family.

243231:GS RS01345
gene id: 243231:GS_RS01345
uniprot id: Q74GH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

243231:GS RS16635
gene id: 243231:GS_RS16635
uniprot id: Q747E8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

243231:GS RS16870
gene id: 243231:GS_RS16870
uniprot id: Q746Z9
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

243231:GS RS11755
gene id: 243231:GS_RS11755
uniprot id: I7FIH1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

243231:GS RS15400
gene id: 243231:GS_RS15400
uniprot id: P61435
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

243231:GS RS05335
gene id: 243231:GS_RS05335
uniprot id: Q74E95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

243231:GS RS02510
gene id: 243231:GS_RS02510
uniprot id: P61389
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

243231:GS RS05645
gene id: 243231:GS_RS05645
uniprot id: Q74E32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

243231:GS RS03930
gene id: 243231:GS_RS03930
uniprot id: Q74F27
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.
messages: Periplasm

243231:GS RS15395
gene id: 243231:GS_RS15395
uniprot id: Q748D8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

243231:GS RS15285
gene id: 243231:GS_RS15285
uniprot id: Q748F9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

243231:GS RS07680
gene id: 243231:GS_RS07680
uniprot id: Q74CY2
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

243231:GS RS02535
gene id: 243231:GS_RS02535
uniprot id: Q74FU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

243231:GS RS11390
gene id: 243231:GS_RS11390
uniprot id: Q74AT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

243231:GS RS10970
gene id: 243231:GS_RS10970
uniprot id: Q74B57
names: Function
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
messages: tRNA nucleotidyltransferase involved in the synthesis of the tRNA CCA terminus. Adds the two cytidine residues to tRNA.

243231:GS RS14020
gene id: 243231:GS_RS14020
uniprot id: Q749E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

243231:GS RS01990
gene id: 243231:GS_RS01990
uniprot id: Q74G49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

243231:GS RS15045
gene id: 243231:GS_RS15045
uniprot id: Q748K9
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

243231:GS RS11895
gene id: 243231:GS_RS11895
uniprot id: Q74AI2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243231:GS RS13405
gene id: 243231:GS_RS13405
uniprot id: Q749S7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

243231:GS RS04665
gene id: 243231:GS_RS04665
uniprot id: Q74EN5
names: Similarity
messages: Belongs to the peptidase M16 family.

243231:GS RS15380
gene id: 243231:GS_RS15380
uniprot id: Q748E1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243231:GS RS15735
gene id: 243231:GS_RS15735
uniprot id: Q747Y2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

243231:GS RS01065
gene id: 243231:GS_RS01065
uniprot id: Q74GN5
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS13605
gene id: 243231:GS_RS13605
uniprot id: Q749N6
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

243231:GS RS05040
gene id: 243231:GS_RS05040
uniprot id: Q74EF7
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

243231:GS RS14705
gene id: 243231:GS_RS14705
uniprot id: Q748S8
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

243231:GS RS03690
gene id: 243231:GS_RS03690
uniprot id: Q74F68
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS02450
gene id: 243231:GS_RS02450
uniprot id: Q74FW2
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

243231:GS RS08910
gene id: 243231:GS_RS08910
uniprot id: Q74C90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

243231:GS RS11745
gene id: 243231:GS_RS11745
uniprot id: Q74AL2
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS11095
gene id: 243231:GS_RS11095
uniprot id: Q74AZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

243231:GS RS15315
gene id: 243231:GS_RS15315
uniprot id: Q748F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

243231:GS RS14220
gene id: 243231:GS_RS14220
uniprot id: Q749B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

243231:GS RS04755
gene id: 243231:GS_RS04755
uniprot id: Q74EL7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

243231:GS RS02100
gene id: 243231:GS_RS02100
uniprot id: Q74G27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

243231:GS RS06325
gene id: 243231:GS_RS06325
uniprot id: Q74DP6
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

243231:GS RS09525
gene id: 243231:GS_RS09525
uniprot id: Q74BY5
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

243231:GS RS00375
gene id: 243231:GS_RS00375
uniprot id: Q74H23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

243231:GS RS01045
gene id: 243231:GS_RS01045
uniprot id: Q74GP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell inner membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

243231:GS RS11835
gene id: 243231:GS_RS11835
uniprot id: Q74AJ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

243231:GS RS15525
gene id: 243231:GS_RS15525
uniprot id: Q748B7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

243231:GS RS10145
gene id: 243231:GS_RS10145
uniprot id: Q74BM2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

243231:GS RS05170
gene id: 243231:GS_RS05170
uniprot id: I7EEY1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243231:GS RS02205
gene id: 243231:GS_RS02205
uniprot id: Q74G11
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

243231:GS RS16325
gene id: 243231:GS_RS16325
uniprot id: Q747K3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

243231:GS RS16415
gene id: 243231:GS_RS16415
uniprot id: Q747I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

243231:GS RS14265
gene id: 243231:GS_RS14265
uniprot id: Q749A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

243231:GS RS12325
gene id: 243231:GS_RS12325
uniprot id: Q74B11
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

243231:GS RS03625
gene id: 243231:GS_RS03625
uniprot id: Q74F83
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

243231:GS RS11975
gene id: 243231:GS_RS11975
uniprot id: Q74AG7
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS05515
gene id: 243231:GS_RS05515
uniprot id: Q74E58
names: Similarity
messages: Belongs to the citrate synthase family.

243231:GS RS07920
gene id: 243231:GS_RS07920
uniprot id: Q74CT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

243231:GS RS06380
gene id: 243231:GS_RS06380
uniprot id: Q74DN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).

243231:GS RS03020
gene id: 243231:GS_RS03020
uniprot id: Q74FK1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

243231:GS RS17295
gene id: 243231:GS_RS17295
uniprot id: Q746R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

243231:GS RS11400
gene id: 243231:GS_RS11400
uniprot id: Q74AT0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

243231:GS RS11625
gene id: 243231:GS_RS11625
uniprot id: Q74AN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

243231:GS RS12580
gene id: 243231:GS_RS12580
uniprot id: Q74A86
names: Cofactor
names: Disruption Phenotype
names: Function
names: Induction
names: Subcellular Location Annotation
messages: Binds 6 low-spin heme groups per subunit.
messages: Cell outer membrane
messages: Cell surface
messages: Deletion of the gene inhibits Fe(3+) oxide reduction, but does not impact reduction of fumarate or Fe(3+) citrate. Deletion negatively impacts the expression of omcT.
messages: Expressed in the presence of insoluble Fe(3+) oxide and during growth with fumarate as the sole electron acceptor, but not during growth on soluble Fe(3+) citrate (PubMed:16332857). Induced in the cocultures with G. metallireducens (PubMed:23377933).
messages: Plays an important role in extracellular electron transfer. Can transfer electrons to insoluble Fe(3+) oxides as well as other extracellular electron acceptors, including Mn(4+) oxide and humic substances (PubMed:16332857, PubMed:20400557, PubMed:21236241). Essential for direct interspecies electron transfer (DIET) in cocultures with G. metallireducens (PubMed:23377933).

243231:GS RS00255
gene id: 243231:GS_RS00255
uniprot id: Q749Z7
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

243231:GS RS13165
gene id: 243231:GS_RS13165
uniprot id: Q749X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

243231:GS RS00510
gene id: 243231:GS_RS00510
uniprot id: Q74GZ7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

243231:GS RS01620
gene id: 243231:GS_RS01620
uniprot id: Q74GC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

243231:GS RS03835
gene id: 243231:GS_RS03835
uniprot id: Q74F43
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243231:GS RS12470
gene id: 243231:GS_RS12470
uniprot id: Q74AA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

243231:GS RS00470
gene id: 243231:GS_RS00470
uniprot id: Q74H03
names: Similarity
messages: Belongs to the HdrA family.

243231:GS RS16655
gene id: 243231:GS_RS16655
uniprot id: Q747E4
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

243231:GS RS17150
gene id: 243231:GS_RS17150
uniprot id: Q746U4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

243231:GS RS15030
gene id: 243231:GS_RS15030
uniprot id: Q748L2
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

243231:GS RS17280
gene id: 243231:GS_RS17280
uniprot id: Q746R8
names: Similarity
messages: Belongs to the glutamate synthase family.

243231:GS RS09770
gene id: 243231:GS_RS09770
uniprot id: Q74BT4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

243231:GS RS05915
gene id: 243231:GS_RS05915
uniprot id: Q74DY2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

243231:GS RS04185
gene id: 243231:GS_RS04185
uniprot id: Q74EX8
names: Similarity
messages: Belongs to the P(II) protein family.

243231:GS RS14130
gene id: 243231:GS_RS14130
uniprot id: Q749C6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

243231:GS RS11725
gene id: 243231:GS_RS11725
uniprot id: Q74AL6
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

243231:GS RS16810
gene id: 243231:GS_RS16810
uniprot id: Q747B1
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS10375
gene id: 243231:GS_RS10375
uniprot id: Q74BH5
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

243231:GS RS07760
gene id: 243231:GS_RS07760
uniprot id: Q74CW6
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS10040
gene id: 243231:GS_RS10040
uniprot id: Q74BP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

243231:GS RS08750
gene id: 243231:GS_RS08750
uniprot id: Q74CC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

243231:GS RS03280
gene id: 243231:GS_RS03280
uniprot id: Q74FF1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent (By similarity).
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
messages: The Clp repeat (R) domain probably functions as a substrate-discriminating domain, recruiting aggregated proteins to the ClpB hexamer and/or stabilizing bound proteins. The NBD2 domain is responsible for oligomerization, whereas the NBD1 domain stabilizes the hexamer probably in an ATP-dependent manner. The movement of the coiled-coil domain is essential for ClpB ability to rescue proteins from an aggregated state, probably by pulling apart large aggregated proteins, which are bound between the coiled-coils motifs of adjacent ClpB subunits in the functional hexamer (By similarity).

243231:GS RS14205
gene id: 243231:GS_RS14205
uniprot id: Q749B4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

243231:GS RS07145
gene id: 243231:GS_RS07145
uniprot id: Q74D82
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

243231:GS RS15220
gene id: 243231:GS_RS15220
uniprot id: Q748H3
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS07890
gene id: 243231:GS_RS07890
uniprot id: Q74CT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

243231:GS RS03190
gene id: 243231:GS_RS03190
uniprot id: Q74FG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

243231:GS RS06305
gene id: 243231:GS_RS06305
uniprot id: P60789
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

243231:GS RS09520
gene id: 243231:GS_RS09520
uniprot id: Q74BY6
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

243231:GS RS11825
gene id: 243231:GS_RS11825
uniprot id: Q74AJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

243231:GS RS10475
gene id: 243231:GS_RS10475
uniprot id: Q74BF4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

243231:GS RS04730
gene id: 243231:GS_RS04730
uniprot id: Q74EM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

243231:GS RS14195
gene id: 243231:GS_RS14195
uniprot id: Q749B5
names: Similarity
messages: Belongs to the DNA photolyase class-2 family.

243231:GS RS09205
gene id: 243231:GS_RS09205
uniprot id: Q74C40
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

243231:GS RS01865
gene id: 243231:GS_RS01865
uniprot id: Q74G72
names: Similarity
messages: Belongs to the GcvT family.

243231:GS RS14280
gene id: 243231:GS_RS14280
uniprot id: Q749A0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

243231:GS RS00125
gene id: 243231:GS_RS00125
uniprot id: Q74H68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

243231:GS RS03520
gene id: 243231:GS_RS03520
uniprot id: Q74FA4
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS09705
gene id: 243231:GS_RS09705
uniprot id: Q74BV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

243231:GS RS10485
gene id: 243231:GS_RS10485
uniprot id: Q74BF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

243231:GS RS04170
gene id: 243231:GS_RS04170
uniprot id: Q74EY1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

243231:GS RS01650
gene id: 243231:GS_RS01650
uniprot id: Q74GB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

243231:GS RS07790
gene id: 243231:GS_RS07790
uniprot id: Q74CV9
names: Similarity
messages: Belongs to the UPF0045 family.

243231:GS RS03515
gene id: 243231:GS_RS03515
uniprot id: Q74FA5
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS12465
gene id: 243231:GS_RS12465
uniprot id: Q74AA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

243231:GS RS15785
gene id: 243231:GS_RS15785
uniprot id: Q747X2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

243231:GS RS05575
gene id: 243231:GS_RS05575
uniprot id: Q74E46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

243231:GS RS03935
gene id: 243231:GS_RS03935
uniprot id: Q74F26
names: Cofactor
names: Subunit
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: Heterodimer of a large and a small subunit.

243231:GS RS01790
gene id: 243231:GS_RS01790
uniprot id: Q74G87
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

243231:GS RS17195
gene id: 243231:GS_RS17195
uniprot id: Q746T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

243231:GS RS15080
gene id: 243231:GS_RS15080
uniprot id: Q748K2
names: Similarity
messages: Belongs to the CobH/CbiC family.

243231:GS RS03670
gene id: 243231:GS_RS03670
uniprot id: Q74F73
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

243231:GS RS00890
gene id: 243231:GS_RS00890
uniprot id: Q74GS1
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

243231:GS RS15530
gene id: 243231:GS_RS15530
uniprot id: Q748B6
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS06495
gene id: 243231:GS_RS06495
uniprot id: Q74DL2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243231:GS RS14810
gene id: 243231:GS_RS14810
uniprot id: Q748Q7
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

243231:GS RS12330
gene id: 243231:GS_RS12330
uniprot id: Q74B10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

243231:GS RS15660
gene id: 243231:GS_RS15660
uniprot id: Q747Z8
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

243231:GS RS06730
gene id: 243231:GS_RS06730
uniprot id: Q74DG4
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

243231:GS RS17345
gene id: 243231:GS_RS17345
uniprot id: Q746Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

243231:GS RS00430
gene id: 243231:GS_RS00430
uniprot id: Q74H11
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

243231:GS RS06960
gene id: 243231:GS_RS06960
uniprot id: Q74DB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

243231:GS RS16865
gene id: 243231:GS_RS16865
uniprot id: Q747A0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

243231:GS RS16615
gene id: 243231:GS_RS16615
uniprot id: Q747F1
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS17245
gene id: 243231:GS_RS17245
uniprot id: Q746S5
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

243231:GS RS04290
gene id: 243231:GS_RS04290
uniprot id: Q74EV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

243231:GS RS08195
gene id: 243231:GS_RS08195
uniprot id: Q74CN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

243231:GS RS02035
gene id: 243231:GS_RS02035
uniprot id: Q74G40
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

243231:GS RS17115
gene id: 243231:GS_RS17115
uniprot id: Q746V1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Heterodimer of a large and a small subunit.

243231:GS RS10430
gene id: 243231:GS_RS10430
uniprot id: Q74BG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

243231:GS RS00765
gene id: 243231:GS_RS00765
uniprot id: P61701
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

243231:GS RS14400
gene id: 243231:GS_RS14400
uniprot id: P62434
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

243231:GS RS08655
gene id: 243231:GS_RS08655
uniprot id: Q74CE2
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS06205
gene id: 243231:GS_RS06205
uniprot id: Q74DR9
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

243231:GS RS10340
gene id: 243231:GS_RS10340
uniprot id: Q74BI1
names: Similarity
messages: Belongs to the peptidase U62 family.

243231:GS RS02260
gene id: 243231:GS_RS02260
uniprot id: Q74FZ8
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

243231:GS RS03055
gene id: 243231:GS_RS03055
uniprot id: Q74FJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

243231:GS RS07635
gene id: 243231:GS_RS07635
uniprot id: P60804
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

243231:GS RS09975
gene id: 243231:GS_RS09975
uniprot id: Q74BQ7
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS05275
gene id: 243231:GS_RS05275
uniprot id: Q74EA7
names: Similarity
messages: Belongs to the UPF0047 family.

243231:GS RS08815
gene id: 243231:GS_RS08815
uniprot id: Q74CA9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

243231:GS RS14865
gene id: 243231:GS_RS14865
uniprot id: Q748P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

243231:GS RS13980
gene id: 243231:GS_RS13980
uniprot id: Q749F7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

243231:GS RS17355
gene id: 243231:GS_RS17355
uniprot id: Q746Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

243231:GS RS13110
gene id: 243231:GS_RS13110
uniprot id: Q749Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

243231:GS RS15435
gene id: 243231:GS_RS15435
uniprot id: Q748D2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm

243231:GS RS00340
gene id: 243231:GS_RS00340
uniprot id: Q74H28
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

243231:GS RS05120
gene id: 243231:GS_RS05120
uniprot id: Q74ED9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

243231:GS RS03525
gene id: 243231:GS_RS03525
uniprot id: Q74FA3
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS04300
gene id: 243231:GS_RS04300
uniprot id: Q74EV2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

243231:GS RS07610
gene id: 243231:GS_RS07610
uniprot id: Q74CZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

243231:GS RS04725
gene id: 243231:GS_RS04725
uniprot id: Q74EM3
names: Similarity
messages: Belongs to the P(II) protein family.

243231:GS RS08030
gene id: 243231:GS_RS08030
uniprot id: Q74CR3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

243231:GS RS04180
gene id: 243231:GS_RS04180
uniprot id: Q74EX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

243231:GS RS01730
gene id: 243231:GS_RS01730
uniprot id: Q74G98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

243231:GS RS11240
gene id: 243231:GS_RS11240
uniprot id: Q74AW1
names: Similarity
messages: Belongs to the YicC/YloC family.

243231:GS RS03310
gene id: 243231:GS_RS03310
uniprot id: Q74FE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

243231:GS RS10330
gene id: 243231:GS_RS10330
uniprot id: Q74BI4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

243231:GS RS06680
gene id: 243231:GS_RS06680
uniprot id: Q74DH4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

243231:GS RS05970
gene id: 243231:GS_RS05970
uniprot id: Q74DW8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243231:GS RS12340
gene id: 243231:GS_RS12340
uniprot id: Q74B31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

243231:GS RS08230
gene id: 243231:GS_RS08230
uniprot id: Q74CM4
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS10185
gene id: 243231:GS_RS10185
uniprot id: Q74BL4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

243231:GS RS01605
gene id: 243231:GS_RS01605
uniprot id: Q74GC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

243231:GS RS13240
gene id: 243231:GS_RS13240
uniprot id: Q749W1
names: Similarity
messages: Belongs to the UPF0047 family.

243231:GS RS09675
gene id: 243231:GS_RS09675
uniprot id: Q74BV9
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS14495
gene id: 243231:GS_RS14495
uniprot id: I7FKG4
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS01375
gene id: 243231:GS_RS01375
uniprot id: Q74GG9
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS15055
gene id: 243231:GS_RS15055
uniprot id: Q748K7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

243231:GS RS05000
gene id: 243231:GS_RS05000
uniprot id: Q74EG5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

243231:GS RS01625
gene id: 243231:GS_RS01625
uniprot id: Q74GB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Cell membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

243231:GS RS10135
gene id: 243231:GS_RS10135
uniprot id: Q74BM4
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

243231:GS RS11470
gene id: 243231:GS_RS11470
uniprot id: Q74AR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

243231:GS RS12220
gene id: 243231:GS_RS12220
uniprot id: Q74AE5
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS11340
gene id: 243231:GS_RS11340
uniprot id: Q74AU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

243231:GS RS11280
gene id: 243231:GS_RS11280
uniprot id: Q74AV3
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

243231:GS RS16730
gene id: 243231:GS_RS16730
uniprot id: Q747C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

243231:GS RS07280
gene id: 243231:GS_RS07280
uniprot id: Q74D56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

243231:GS RS07295
gene id: 243231:GS_RS07295
uniprot id: Q74D53
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

243231:GS RS16060
gene id: 243231:GS_RS16060
uniprot id: Q747R4
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

243231:GS RS04325
gene id: 243231:GS_RS04325
uniprot id: Q74EU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

243231:GS RS00660
gene id: 243231:GS_RS00660
uniprot id: Q74GW7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

243231:GS RS08045
gene id: 243231:GS_RS08045
uniprot id: Q74CR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

243231:GS RS06550
gene id: 243231:GS_RS06550
uniprot id: Q74DK1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

243231:GS RS12365
gene id: 243231:GS_RS12365
uniprot id: Q74B25
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS16080
gene id: 243231:GS_RS16080
uniprot id: Q747R0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

243231:GS RS05905
gene id: 243231:GS_RS05905
uniprot id: Q74DY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

243231:GS RS15260
gene id: 243231:GS_RS15260
uniprot id: Q748G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

243231:GS RS04460
gene id: 243231:GS_RS04460
uniprot id: Q74ES0
names: Similarity
messages: Belongs to the acylphosphatase family.

243231:GS RS04740
gene id: 243231:GS_RS04740
uniprot id: Q74EM0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

243231:GS RS02435
gene id: 243231:GS_RS02435
uniprot id: Q74FW5
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS07980
gene id: 243231:GS_RS07980
uniprot id: Q74CS3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

243231:GS RS02730
gene id: 243231:GS_RS02730
uniprot id: Q74FQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

243231:GS RS08415
gene id: 243231:GS_RS08415
uniprot id: Q74CI6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

243231:GS RS05775
gene id: 243231:GS_RS05775
uniprot id: Q74E11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPS (TC 1.B.20) family.
messages: Cell outer membrane
messages: Membrane

243231:GS RS04595
gene id: 243231:GS_RS04595
uniprot id: Q74EP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

243231:GS RS09040
gene id: 243231:GS_RS09040
uniprot id: Q74C71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

243231:GS RS08155
gene id: 243231:GS_RS08155
uniprot id: Q74CP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

243231:GS RS11630
gene id: 243231:GS_RS11630
uniprot id: Q74AN5
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS11080
gene id: 243231:GS_RS11080
uniprot id: Q74AZ3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

243231:GS RS11435
gene id: 243231:GS_RS11435
uniprot id: Q74AS3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

243231:GS RS00750
gene id: 243231:GS_RS00750
uniprot id: P62215
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

243231:GS RS02925
gene id: 243231:GS_RS02925
uniprot id: Q74FL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

243231:GS RS00175
gene id: 243231:GS_RS00175
uniprot id: Q74H58
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

243231:GS RS07345
gene id: 243231:GS_RS07345
uniprot id: Q74D43
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS14390
gene id: 243231:GS_RS14390
uniprot id: Q748Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

243231:GS RS02030
gene id: 243231:GS_RS02030
uniprot id: Q74G41
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

243231:GS RS06970
gene id: 243231:GS_RS06970
uniprot id: Q74DB6
names: Subcellular Location Annotation
messages: Cytoplasm

243231:GS RS11580
gene id: 243231:GS_RS11580
uniprot id: Q74AP5
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

243231:GS RS00945
gene id: 243231:GS_RS00945
uniprot id: Q74GR0
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS01815
gene id: 243231:GS_RS01815
uniprot id: Q74G82
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

243231:GS RS02225
gene id: 243231:GS_RS02225
uniprot id: Q74G06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

243231:GS RS02060
gene id: 243231:GS_RS02060
uniprot id: Q74G35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

243231:GS RS05825
gene id: 243231:GS_RS05825
uniprot id: Q74E01
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS15545
gene id: 243231:GS_RS15545
uniprot id: P60536
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

243231:GS RS04110
gene id: 243231:GS_RS04110
uniprot id: Q74EZ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

243231:GS RS00500
gene id: 243231:GS_RS00500
uniprot id: Q74GZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

243231:GS RS16005
gene id: 243231:GS_RS16005
uniprot id: Q747S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

243231:GS RS14380
gene id: 243231:GS_RS14380
uniprot id: Q748Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

243231:GS RS04350
gene id: 243231:GS_RS04350
uniprot id: Q74EU2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

243231:GS RS06475
gene id: 243231:GS_RS06475
uniprot id: Q74DL6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243231:GS RS01890
gene id: 243231:GS_RS01890
uniprot id: P61196
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

243231:GS RS10115
gene id: 243231:GS_RS10115
uniprot id: Q74BM8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

243231:GS RS12310
gene id: 243231:GS_RS12310
uniprot id: Q74B14
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

243231:GS RS01145
gene id: 243231:GS_RS01145
uniprot id: Q74GL8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

243231:GS RS13910
gene id: 243231:GS_RS13910
uniprot id: Q749H1
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

243231:GS RS06025
gene id: 243231:GS_RS06025
uniprot id: Q74DV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

243231:GS RS06885
gene id: 243231:GS_RS06885
uniprot id: Q74DD2
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

243231:GS RS15015
gene id: 243231:GS_RS15015
uniprot id: Q748L4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

243231:GS RS04990
gene id: 243231:GS_RS04990
uniprot id: Q74EG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

243231:GS RS11415
gene id: 243231:GS_RS11415
uniprot id: Q74AS7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

243231:GS RS02485
gene id: 243231:GS_RS02485
uniprot id: I7EP07
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS01875
gene id: 243231:GS_RS01875
uniprot id: Q74G70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

243231:GS RS00020
gene id: 243231:GS_RS00020
uniprot id: Q74H89
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

243231:GS RS12745
gene id: 243231:GS_RS12745
uniprot id: A0A4W3
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

243231:GS RS14255
gene id: 243231:GS_RS14255
uniprot id: Q749A5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

243231:GS RS01195
gene id: 243231:GS_RS01195
uniprot id: Q74GK7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

243231:GS RS11510
gene id: 243231:GS_RS11510
uniprot id: Q74AR0
names: Similarity
messages: Belongs to the AlaDH/PNT family.

243231:GS RS13810
gene id: 243231:GS_RS13810
uniprot id: Q749J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

243231:GS RS13800
gene id: 243231:GS_RS13800
uniprot id: Q749J3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

243231:GS RS16480
gene id: 243231:GS_RS16480
uniprot id: Q747H4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

243231:GS RS14340
gene id: 243231:GS_RS14340
uniprot id: P61063
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

243231:GS RS04750
gene id: 243231:GS_RS04750
uniprot id: Q74EL8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

243231:GS RS09655
gene id: 243231:GS_RS09655
uniprot id: Q74BW2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.

243231:GS RS01520
gene id: 243231:GS_RS01520
uniprot id: Q74GE1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

243231:GS RS11060
gene id: 243231:GS_RS11060
uniprot id: Q74AZ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

243231:GS RS01000
gene id: 243231:GS_RS01000
uniprot id: Q74GP9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

243231:GS RS13550
gene id: 243231:GS_RS13550
uniprot id: Q749P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

243231:GS RS04070
gene id: 243231:GS_RS04070
uniprot id: Q74F00
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

243231:GS RS06190
gene id: 243231:GS_RS06190
uniprot id: Q74DS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

243231:GS RS11575
gene id: 243231:GS_RS11575
uniprot id: Q74AP6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

243231:GS RS09415
gene id: 243231:GS_RS09415
uniprot id: Q74C05
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

243231:GS RS17190
gene id: 243231:GS_RS17190
uniprot id: Q746T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

243231:GS RS00250
gene id: 243231:GS_RS00250
uniprot id: Q749Z8
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

243231:GS RS02530
gene id: 243231:GS_RS02530
uniprot id: P60926
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

243231:GS RS07580
gene id: 243231:GS_RS07580
uniprot id: Q74CZ8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

243231:GS RS04130
gene id: 243231:GS_RS04130
uniprot id: Q74EY9
names: Similarity
messages: Belongs to the peptidase S49 family.

243231:GS RS00965
gene id: 243231:GS_RS00965
uniprot id: Q74GQ7
names: Similarity
messages: Belongs to the DEAD box helicase family.

243231:GS RS04360
gene id: 243231:GS_RS04360
uniprot id: Q74EU0
names: Similarity
messages: Belongs to the peptidase C40 family.

243231:GS RS02515
gene id: 243231:GS_RS02515
uniprot id: Q74FV0
names: Similarity
messages: Belongs to the UPF0166 family.

243231:GS RS09610
gene id: 243231:GS_RS09610
uniprot id: Q74BW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

243231:GS RS05865
gene id: 243231:GS_RS05865
uniprot id: Q74DZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

243231:GS RS11720
gene id: 243231:GS_RS11720
uniprot id: Q74AL7
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

243231:GS RS01745
gene id: 243231:GS_RS01745
uniprot id: Q74G95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

243231:GS RS00700
gene id: 243231:GS_RS00700
uniprot id: Q74GV9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

243231:GS RS11420
gene id: 243231:GS_RS11420
uniprot id: Q74AS6
names: Subcellular Location Annotation
messages: Nucleus

243231:GS RS02415
gene id: 243231:GS_RS02415
uniprot id: Q74FW9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

243231:GS RS13770
gene id: 243231:GS_RS13770
uniprot id: Q749J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family. PetJ subfamily.
messages: Cellular thylakoid lumen

243231:GS RS05150
gene id: 243231:GS_RS05150
uniprot id: Q74ED3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243231:GS RS13880
gene id: 243231:GS_RS13880
uniprot id: Q749H7
names: Similarity
messages: Belongs to the LOG family.

243231:GS RS08400
gene id: 243231:GS_RS08400
uniprot id: Q74CI9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

243231:GS RS03420
gene id: 243231:GS_RS03420
uniprot id: Q74FC3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

243231:GS RS08735
gene id: 243231:GS_RS08735
uniprot id: Q74CC6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

243231:GS RS12460
gene id: 243231:GS_RS12460
uniprot id: Q74AB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

243231:GS RS04305
gene id: 243231:GS_RS04305
uniprot id: Q74EV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

243231:GS RS13590
gene id: 243231:GS_RS13590
uniprot id: Q749N9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

243231:GS RS14305
gene id: 243231:GS_RS14305
uniprot id: Q748Z6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

243231:GS RS15515
gene id: 243231:GS_RS15515
uniprot id: Q748B9
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

243231:GS RS14300
gene id: 243231:GS_RS14300
uniprot id: Q748Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

243231:GS RS14395
gene id: 243231:GS_RS14395
uniprot id: Q748Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

243231:GS RS01660
gene id: 243231:GS_RS01660
uniprot id: Q74GB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

243231:GS RS11855
gene id: 243231:GS_RS11855
uniprot id: Q74AJ1
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS04230
gene id: 243231:GS_RS04230
uniprot id: Q74EW5
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS04475
gene id: 243231:GS_RS04475
uniprot id: I7FK74
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

243231:GS RS16565
gene id: 243231:GS_RS16565
uniprot id: Q747F9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

243231:GS RS16310
gene id: 243231:GS_RS16310
uniprot id: Q747K6
names: Disruption Phenotype
names: Function
names: Induction
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme c groups covalently per subunit.
messages: Cell inner membrane
messages: Constitutively expressed.
messages: Disruption of this gene eliminates the ability of G.sulfurreducens to reduce soluble Fe(III) citrate, Fe(III)-EDTA, and insoluble Mn(IV) oxides, electron acceptors with potentials greater than 0.1 V versus the standard hydrogen electrode (SHE), but the imcH mutant retains the ability to reduce Fe(III) oxides with potentials of <-0.1 V versus SHE. The imcH mutant fails to grow on electrodes poised at +0.24 V versus SHE, but switching electrodes to -0.1 V versus SHE triggers exponential growth. Growth with fumarate as the electron acceptor is unaffected in the deletion mutant.
messages: Redox protein involved in a high-potential metal respiratory pathway. Is required only for electron transfer to terminal extracellular electron acceptors with redox potentials higher than -0.1 V. ImcH likely transfers electrons from the quinone pool to a periplasmic acceptor.

243231:GS RS02275
gene id: 243231:GS_RS02275
uniprot id: Q74FZ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Membrane
messages: Monomer.

243231:GS RS01100
gene id: 243231:GS_RS01100
uniprot id: Q74GM8
names: Similarity
messages: Belongs to the SCO1/2 family.

243231:GS RS01700
gene id: 243231:GS_RS01700
uniprot id: Q74GA4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

243231:GS RS12485
gene id: 243231:GS_RS12485
uniprot id: Q74AA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

243231:GS RS02790
gene id: 243231:GS_RS02790
uniprot id: Q74DL9
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

243231:GS RS15415
gene id: 243231:GS_RS15415
uniprot id: Q748D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that is essential for cell division.

243231:GS RS10045
gene id: 243231:GS_RS10045
uniprot id: Q74BP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

243231:GS RS00005
gene id: 243231:GS_RS00005
uniprot id: Q74GG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

243231:GS RS03030
gene id: 243231:GS_RS03030
uniprot id: Q74FJ9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

243231:GS RS11020
gene id: 243231:GS_RS11020
uniprot id: P60500
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

243231:GS RS02605
gene id: 243231:GS_RS02605
uniprot id: Q74FT4
names: Similarity
messages: Belongs to the DEAD box helicase family.

243231:GS RS01725
gene id: 243231:GS_RS01725
uniprot id: Q74G99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

243231:GS RS14370
gene id: 243231:GS_RS14370
uniprot id: I7F9P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

243231:GS RS04775
gene id: 243231:GS_RS04775
uniprot id: Q74EL3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

243231:GS RS07485
gene id: 243231:GS_RS07485
uniprot id: Q74D15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

243231:GS RS09650
gene id: 243231:GS_RS09650
uniprot id: P61304
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

243231:GS RS05605
gene id: 243231:GS_RS05605
uniprot id: Q74E40
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243231:GS RS11025
gene id: 243231:GS_RS11025
uniprot id: Q74B47
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

243231:GS RS14860
gene id: 243231:GS_RS14860
uniprot id: Q748P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

243231:GS RS14465
gene id: 243231:GS_RS14465
uniprot id: Q748X5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

243231:GS RS09985
gene id: 243231:GS_RS09985
uniprot id: Q74BQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

243231:GS RS13520
gene id: 243231:GS_RS13520
uniprot id: Q749Q2
names: Similarity
messages: Belongs to the MlaA family.

243231:GS RS09595
gene id: 243231:GS_RS09595
uniprot id: Q74BX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

243231:GS RS17075
gene id: 243231:GS_RS17075
uniprot id: Q746W0
names: Function
names: Similarity
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.

243231:GS RS12475
gene id: 243231:GS_RS12475
uniprot id: Q74AA7
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS07205
gene id: 243231:GS_RS07205
uniprot id: Q74D69
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

243231:GS RS08000
gene id: 243231:GS_RS08000
uniprot id: Q74CR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

243231:GS RS12215
gene id: 243231:GS_RS12215
uniprot id: Q74AE6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

243231:GS RS12115
gene id: 243231:GS_RS12115
uniprot id: Q74B24
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

243231:GS RS00805
gene id: 243231:GS_RS00805
uniprot id: Q74GT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

243231:GS RS13400
gene id: 243231:GS_RS13400
uniprot id: Q749S8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

243231:GS RS07620
gene id: 243231:GS_RS07620
uniprot id: Q74CZ2
names: Similarity
messages: Belongs to the UPF0597 family.

243231:GS RS02920
gene id: 243231:GS_RS02920
uniprot id: P61411
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

243231:GS RS16495
gene id: 243231:GS_RS16495
uniprot id: Q747H2
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

243231:GS RS14110
gene id: 243231:GS_RS14110
uniprot id: Q749D0
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

243231:GS RS13525
gene id: 243231:GS_RS13525
uniprot id: Q749Q1
names: Similarity
messages: Belongs to the MlaA family.

243231:GS RS15305
gene id: 243231:GS_RS15305
uniprot id: Q748F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

243231:GS RS11495
gene id: 243231:GS_RS11495
uniprot id: Q74AR3
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

243231:GS RS02560
gene id: 243231:GS_RS02560
uniprot id: Q74FU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

243231:GS RS15595
gene id: 243231:GS_RS15595
uniprot id: Q748B1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

243231:GS RS01635
gene id: 243231:GS_RS01635
uniprot id: Q74GB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

243231:GS RS03325
gene id: 243231:GS_RS03325
uniprot id: Q74FE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

243231:GS RS08610
gene id: 243231:GS_RS08610
uniprot id: Q74CF1
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

243231:GS RS11760
gene id: 243231:GS_RS11760
uniprot id: Q74AL0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

243231:GS RS17235
gene id: 243231:GS_RS17235
uniprot id: Q746S7
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

243231:GS RS05665
gene id: 243231:GS_RS05665
uniprot id: Q74E27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

243231:GS RS12225
gene id: 243231:GS_RS12225
uniprot id: Q74AE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family. PetJ subfamily.
messages: Cellular thylakoid lumen

243231:GS RS05165
gene id: 243231:GS_RS05165
uniprot id: Q74EC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

243231:GS RS09060
gene id: 243231:GS_RS09060
uniprot id: Q74C68
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

243231:GS RS05110
gene id: 243231:GS_RS05110
uniprot id: Q74EE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

243231:GS RS08170
gene id: 243231:GS_RS08170
uniprot id: Q74CN7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

243231:GS RS04085
gene id: 243231:GS_RS04085
uniprot id: Q74EZ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

243231:GS RS01935
gene id: 243231:GS_RS01935
uniprot id: Q74G60
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS09470
gene id: 243231:GS_RS09470
uniprot id: Q74BZ5
names: Subcellular Location Annotation
messages: Cytoplasm

243231:GS RS11605
gene id: 243231:GS_RS11605
uniprot id: Q74AP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

243231:GS RS10465
gene id: 243231:GS_RS10465
uniprot id: Q74BF6
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

243231:GS RS10190
gene id: 243231:GS_RS10190
uniprot id: Q74BL3
names: Similarity
messages: Belongs to the bacterial secretin family.

243231:GS RS13505
gene id: 243231:GS_RS13505
uniprot id: Q749Q7
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS01860
gene id: 243231:GS_RS01860
uniprot id: Q74G73
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

243231:GS RS13720
gene id: 243231:GS_RS13720
uniprot id: Q749L1
names: Caution
names: Function
names: Induction
names: PTM
names: Subcellular Location Annotation
messages: Binds 12 heme c groups per subunit.
messages: Cell outer membrane
messages: Not involved in Fe(3+) reduction.
messages: Not regulated by Fe(3+).
messages: Was initially thought to act as an electron-transport mediator in the dissimilatory reduction of Fe(3+).

243231:GS RS17000
gene id: 243231:GS_RS17000
uniprot id: Q746X5
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS09645
gene id: 243231:GS_RS09645
uniprot id: P60482
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

243231:GS RS01315
gene id: 243231:GS_RS01315
uniprot id: Q74GI1
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS04695
gene id: 243231:GS_RS04695
uniprot id: Q74EM9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

243231:GS RS02330
gene id: 243231:GS_RS02330
uniprot id: Q74FY6
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

243231:GS RS02110
gene id: 243231:GS_RS02110
uniprot id: Q3V8D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

243231:GS RS02115
gene id: 243231:GS_RS02115
uniprot id: Q3V8D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

243231:GS RS12895
gene id: 243231:GS_RS12895
uniprot id: Q74A24
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS06630
gene id: 243231:GS_RS06630
uniprot id: Q74DI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

243231:GS RS00790
gene id: 243231:GS_RS00790
uniprot id: P61523
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

243231:GS RS15745
gene id: 243231:GS_RS15745
uniprot id: Q747Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

243231:GS RS02890
gene id: 243231:GS_RS02890
uniprot id: Q74FM5
names: Subcellular Location Annotation
messages: Cytoplasm

243231:GS RS09540
gene id: 243231:GS_RS09540
uniprot id: Q74BY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

243231:GS RS14270
gene id: 243231:GS_RS14270
uniprot id: Q749A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

243231:GS RS00165
gene id: 243231:GS_RS00165
uniprot id: Q74H60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

243231:GS RS00155
gene id: 243231:GS_RS00155
uniprot id: Q74H62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

243231:GS RS15605
gene id: 243231:GS_RS15605
uniprot id: Q748A9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

243231:GS RS15450
gene id: 243231:GS_RS15450
uniprot id: P60396
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

243231:GS RS13035
gene id: 243231:GS_RS13035
uniprot id: Q749Z7
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

243231:GS RS03235
gene id: 243231:GS_RS03235
uniprot id: Q74FF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

243231:GS RS15105
gene id: 243231:GS_RS15105
uniprot id: Q748J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell inner membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

243231:GS RS14460
gene id: 243231:GS_RS14460
uniprot id: Q748X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

243231:GS RS02880
gene id: 243231:GS_RS02880
uniprot id: Q74FM7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

243231:GS RS08510
gene id: 243231:GS_RS08510
uniprot id: Q74CG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

243231:GS RS06275
gene id: 243231:GS_RS06275
uniprot id: Q74DQ5
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS06865
gene id: 243231:GS_RS06865
uniprot id: Q74DD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

243231:GS RS16305
gene id: 243231:GS_RS16305
uniprot id: Q747K8
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

243231:GS RS07995
gene id: 243231:GS_RS07995
uniprot id: Q74CS0
names: Similarity
messages: Belongs to the fabD family.

243231:GS RS08410
gene id: 243231:GS_RS08410
uniprot id: Q74CI7
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

243231:GS RS12435
gene id: 243231:GS_RS12435
uniprot id: Q74AB7
names: Similarity
messages: Belongs to the VapB family.

243231:GS RS16560
gene id: 243231:GS_RS16560
uniprot id: P60837
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

243231:GS RS11395
gene id: 243231:GS_RS11395
uniprot id: Q74AT1
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS13090
gene id: 243231:GS_RS13090
uniprot id: Q749Z0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

243231:GS RS00630
gene id: 243231:GS_RS00630
uniprot id: Q74GX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

243231:GS RS04310
gene id: 243231:GS_RS04310
uniprot id: Q74EV0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

243231:GS RS04510
gene id: 243231:GS_RS04510
uniprot id: Q74ER2
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

243231:GS RS09075
gene id: 243231:GS_RS09075
uniprot id: Q74C65
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

243231:GS RS06700
gene id: 243231:GS_RS06700
uniprot id: Q74DH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

243231:GS RS15585
gene id: 243231:GS_RS15585
uniprot id: Q748B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

243231:GS RS01610
gene id: 243231:GS_RS01610
uniprot id: Q74GC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP I family.
messages: Membrane

243231:GS RS01845
gene id: 243231:GS_RS01845
uniprot id: Q74G76
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

243231:GS RS02525
gene id: 243231:GS_RS02525
uniprot id: Q74FU8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

243231:GS RS01665
gene id: 243231:GS_RS01665
uniprot id: Q74GB1
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS00535
gene id: 243231:GS_RS00535
uniprot id: Q74GZ1
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

243231:GS RS00140
gene id: 243231:GS_RS00140
uniprot id: Q74H65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

243231:GS RS00445
gene id: 243231:GS_RS00445
uniprot id: Q74H08
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 [2Fe-2S] cluster per subunit.

243231:GS RS12335
gene id: 243231:GS_RS12335
uniprot id: Q74B09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

243231:GS RS04045
gene id: 243231:GS_RS04045
uniprot id: Q74F05
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.

243231:GS RS08780
gene id: 243231:GS_RS08780
uniprot id: Q74CB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

243231:GS RS03945
gene id: 243231:GS_RS03945
uniprot id: Q74F24
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

243231:GS RS03115
gene id: 243231:GS_RS03115
uniprot id: Q74FI1
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

243231:GS RS05815
gene id: 243231:GS_RS05815
uniprot id: Q74E03
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

243231:GS RS15995
gene id: 243231:GS_RS15995
uniprot id: Q747S7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

243231:GS RS06250
gene id: 243231:GS_RS06250
uniprot id: Q74DR0
names: Similarity
messages: Belongs to the SCO1/2 family.

243231:GS RS14325
gene id: 243231:GS_RS14325
uniprot id: Q748Z2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

243231:GS RS04560
gene id: 243231:GS_RS04560
uniprot id: Q74EQ6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

243231:GS RS10150
gene id: 243231:GS_RS10150
uniprot id: Q74BM1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

243231:GS RS08725
gene id: 243231:GS_RS08725
uniprot id: Q74CC8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

243231:GS RS09530
gene id: 243231:GS_RS09530
uniprot id: P61655
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

243231:GS RS09810
gene id: 243231:GS_RS09810
uniprot id: Q74BS5
names: Similarity
messages: Belongs to the CapA family.

243231:GS RS07985
gene id: 243231:GS_RS07985
uniprot id: Q74CS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

243231:GS RS07940
gene id: 243231:GS_RS07940
uniprot id: Q74CT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

243231:GS RS04020
gene id: 243231:GS_RS04020
uniprot id: Q74F10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

243231:GS RS08545
gene id: 243231:GS_RS08545
uniprot id: Q74CG3
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

243231:GS RS14295
gene id: 243231:GS_RS14295
uniprot id: Q748Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

243231:GS RS04495
gene id: 243231:GS_RS04495
uniprot id: Q74ER4
names: Similarity
messages: Belongs to the peptidase U62 family.

243231:GS RS09605
gene id: 243231:GS_RS09605
uniprot id: Q74BW9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

243231:GS RS11660
gene id: 243231:GS_RS11660
uniprot id: Q74AM9
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS04075
gene id: 243231:GS_RS04075
uniprot id: Q74EZ9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

243231:GS RS07340
gene id: 243231:GS_RS07340
uniprot id: Q74D44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

243231:GS RS16370
gene id: 243231:GS_RS16370
uniprot id: Q747J5
names: Similarity
messages: Belongs to the OprB family.

243231:GS RS10555
gene id: 243231:GS_RS10555
uniprot id: Q74BD9
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

243231:GS RS00010
gene id: 243231:GS_RS00010
uniprot id: Q74H91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

243231:GS RS16035
gene id: 243231:GS_RS16035
uniprot id: Q747R9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243231:GS RS15870
gene id: 243231:GS_RS15870
uniprot id: Q747V4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

243231:GS RS13495
gene id: 243231:GS_RS13495
uniprot id: Q749Q9
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

243231:GS RS06490
gene id: 243231:GS_RS06490
uniprot id: Q74DL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

243231:GS RS11795
gene id: 243231:GS_RS11795
uniprot id: Q74AK3
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.

243231:GS RS04255
gene id: 243231:GS_RS04255
uniprot id: Q74EW0
names: Subcellular Location Annotation
messages: Cytoplasm

243231:GS RS08120
gene id: 243231:GS_RS08120
uniprot id: Q74CP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

243231:GS RS06355
gene id: 243231:GS_RS06355
uniprot id: Q74DP0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

243231:GS RS02380
gene id: 243231:GS_RS02380
uniprot id: Q74FX6
names: Subcellular Location Annotation
messages: Mitochondrion

243231:GS RS13000
gene id: 243231:GS_RS13000
uniprot id: Q74A03
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

243231:GS RS03645
gene id: 243231:GS_RS03645
uniprot id: Q74F78
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

243231:GS RS01705
gene id: 243231:GS_RS01705
uniprot id: Q74GA3
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

243231:GS RS16075
gene id: 243231:GS_RS16075
uniprot id: Q747R1
names: Similarity
messages: Belongs to the UPF0234 family.

243231:GS RS13260
gene id: 243231:GS_RS13260
uniprot id: Q749V7
names: Similarity
messages: Belongs to the hemerythrin family.

243231:GS RS04650
gene id: 243231:GS_RS04650
uniprot id: Q74EN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

243231:GS RS14320
gene id: 243231:GS_RS14320
uniprot id: Q748Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

243231:GS RS07390
gene id: 243231:GS_RS07390
uniprot id: Q74D34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

243231:GS RS06600
gene id: 243231:GS_RS06600
uniprot id: Q74DJ0
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

243231:GS RS14230
gene id: 243231:GS_RS14230
uniprot id: I7FIK3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

243231:GS RS15555
gene id: 243231:GS_RS15555
uniprot id: P60581
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

243231:GS RS15135
gene id: 243231:GS_RS15135
uniprot id: Q748J2
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

243231:GS RS01120
gene id: 243231:GS_RS01120
uniprot id: Q74GM4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

243231:GS RS08435
gene id: 243231:GS_RS08435
uniprot id: P61723
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

243231:GS RS13125
gene id: 243231:GS_RS13125
uniprot id: Q749Y3
names: Similarity
messages: Belongs to the GSP E family.

243231:GS RS15385
gene id: 243231:GS_RS15385
uniprot id: Q748E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

243231:GS RS11220
gene id: 243231:GS_RS11220
uniprot id: Q74AW4
names: Similarity
messages: Belongs to the RutC family.

243231:GS RS01125
gene id: 243231:GS_RS01125
uniprot id: Q74GM3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

243231:GS RS00625
gene id: 243231:GS_RS00625
uniprot id: Q74GX4
names: Similarity
messages: Belongs to the peptidase A31 family.

243231:GS RS03905
gene id: 243231:GS_RS03905
uniprot id: Q74F31
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

243231:GS RS14410
gene id: 243231:GS_RS14410
uniprot id: Q748Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

243231:GS RS13775
gene id: 243231:GS_RS13775
uniprot id: Q749J8
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS16875
gene id: 243231:GS_RS16875
uniprot id: P61736
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

243231:GS RS15455
gene id: 243231:GS_RS15455
uniprot id: Q748C9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

243231:GS RS07385
gene id: 243231:GS_RS07385
uniprot id: Q74D35
names: Similarity
messages: Belongs to the transglycosylase Slt family.

243231:GS RS00440
gene id: 243231:GS_RS00440
uniprot id: Q74H09
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

243231:GS RS08445
gene id: 243231:GS_RS08445
uniprot id: Q74CI0
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

243231:GS RS04580
gene id: 243231:GS_RS04580
uniprot id: Q74EQ2
names: Similarity
messages: Belongs to the AOR/FOR family.

243231:GS RS05270
gene id: 243231:GS_RS05270
uniprot id: Q74EA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

243231:GS RS08850
gene id: 243231:GS_RS08850
uniprot id: Q74CA2
names: Similarity
messages: Belongs to the peptidase S41A family.

243231:GS RS06145
gene id: 243231:GS_RS06145
uniprot id: Q74DT1
names: Similarity
messages: Belongs to the peptidase S49 family.

243231:GS RS05235
gene id: 243231:GS_RS05235
uniprot id: Q74EB5
names: Similarity
messages: Belongs to the UPF0225 family.

243231:GS RS05880
gene id: 243231:GS_RS05880
uniprot id: Q74DZ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

243231:GS RS02090
gene id: 243231:GS_RS02090
uniprot id: Q74G29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

243231:GS RS07015
gene id: 243231:GS_RS07015
uniprot id: Q74DA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

243231:GS RS08285
gene id: 243231:GS_RS08285
uniprot id: Q74CL3
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

243231:GS RS01170
gene id: 243231:GS_RS01170
uniprot id: Q74GL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

243231:GS RS06610
gene id: 243231:GS_RS06610
uniprot id: Q74DI8
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

243231:GS RS03760
gene id: 243231:GS_RS03760
uniprot id: Q74F53
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243231:GS RS09635
gene id: 243231:GS_RS09635
uniprot id: Q74BW4
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

243231:GS RS16445
gene id: 243231:GS_RS16445
uniprot id: Q747I1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

243231:GS RS01085
gene id: 243231:GS_RS01085
uniprot id: Q74GN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

243231:GS RS06510
gene id: 243231:GS_RS06510
uniprot id: Q74DK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

243231:GS RS01020
gene id: 243231:GS_RS01020
uniprot id: Q74GP5
names: Subunit
messages: Heterodimer of a large and a small subunit.

243231:GS RS13100
gene id: 243231:GS_RS13100
uniprot id: Q749Y8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

243231:GS RS15700
gene id: 243231:GS_RS15700
uniprot id: Q747Z0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

243231:GS RS06625
gene id: 243231:GS_RS06625
uniprot id: Q74DI5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

243231:GS RS09425
gene id: 243231:GS_RS09425
uniprot id: Q74C03
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

243231:GS RS09400
gene id: 243231:GS_RS09400
uniprot id: Q74C08
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

243231:GS RS05475
gene id: 243231:GS_RS05475
uniprot id: Q74E66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

243231:GS RS07560
gene id: 243231:GS_RS07560
uniprot id: Q74D02
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

243231:GS RS08420
gene id: 243231:GS_RS08420
uniprot id: Q74CI5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

243231:GS RS00035
gene id: 243231:GS_RS00035
uniprot id: P61740
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

243231:GS RS17350
gene id: 243231:GS_RS17350
uniprot id: Q746Q3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

243231:GS RS16590
gene id: 243231:GS_RS16590
uniprot id: Q747F6
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS03290
gene id: 243231:GS_RS03290
uniprot id: Q74FE9
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

243231:GS RS06465
gene id: 243231:GS_RS06465
uniprot id: Q74DL8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243231:GS RS12810
gene id: 243231:GS_RS12810
uniprot id: Q74A41
names: Similarity
messages: Belongs to the DprA/Smf family.

243231:GS RS01775
gene id: 243231:GS_RS01775
uniprot id: Q74G90
names: Similarity
messages: Belongs to the cytochrome c-552 family.

243231:GS RS00820
gene id: 243231:GS_RS00820
uniprot id: Q74GT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

243231:GS RS01655
gene id: 243231:GS_RS01655
uniprot id: Q74GB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

243231:GS RS05895
gene id: 243231:GS_RS05895
uniprot id: Q74DY7
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

243231:GS RS04690
gene id: 243231:GS_RS04690
uniprot id: Q74EN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

243231:GS RS07575
gene id: 243231:GS_RS07575
uniprot id: Q74CZ9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

243231:GS RS05910
gene id: 243231:GS_RS05910
uniprot id: Q74DY3
names: Similarity
messages: Belongs to the disproportionating enzyme family.

243231:GS RS07090
gene id: 243231:GS_RS07090
uniprot id: P60970
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

243231:GS RS00575
gene id: 243231:GS_RS00575
uniprot id: Q74GY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

243231:GS RS04465
gene id: 243231:GS_RS04465
uniprot id: Q74ER9
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

243231:GS RS11270
gene id: 243231:GS_RS11270
uniprot id: Q74AV5
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

243231:GS RS06310
gene id: 243231:GS_RS06310
uniprot id: Q74DP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

243231:GS RS05365
gene id: 243231:GS_RS05365
uniprot id: P62036
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

243231:GS RS05710
gene id: 243231:GS_RS05710
uniprot id: Q74E24
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243231:GS RS12955
gene id: 243231:GS_RS12955
uniprot id: Q74A12
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243231:GS RS16620
gene id: 243231:GS_RS16620
uniprot id: I7FIL7
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS05535
gene id: 243231:GS_RS05535
uniprot id: Q74E54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

243231:GS RS16510
gene id: 243231:GS_RS16510
uniprot id: Q747G9
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

243231:GS RS04285
gene id: 243231:GS_RS04285
uniprot id: Q74EV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

243231:GS RS05370
gene id: 243231:GS_RS05370
uniprot id: Q74E88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

243231:GS RS14240
gene id: 243231:GS_RS14240
uniprot id: Q749A8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

243231:GS RS06090
gene id: 243231:GS_RS06090
uniprot id: Q74DU3
names: Similarity
messages: Belongs to the histone deacetylase family.

243231:GS RS09725
gene id: 243231:GS_RS09725
uniprot id: G5EBD5
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

243231:GS RS02875
gene id: 243231:GS_RS02875
uniprot id: Q74FM8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

243231:GS RS11830
gene id: 243231:GS_RS11830
uniprot id: Q74AJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

243231:GS RS02025
gene id: 243231:GS_RS02025
uniprot id: Q74G42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

243231:GS RS03015
gene id: 243231:GS_RS03015
uniprot id: Q74FK2
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

243231:GS RS06500
gene id: 243231:GS_RS06500
uniprot id: Q74DL1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

243231:GS RS12785
gene id: 243231:GS_RS12785
uniprot id: Q74A46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

243231:GS RS02950
gene id: 243231:GS_RS02950
uniprot id: Q74FL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

243231:GS RS10840
gene id: 243231:GS_RS10840
uniprot id: Q74B83
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

243231:GS RS11735
gene id: 243231:GS_RS11735
uniprot id: Q74AL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

243231:GS RS16440
gene id: 243231:GS_RS16440
uniprot id: Q747I2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

243231:GS RS08035
gene id: 243231:GS_RS08035
uniprot id: Q74CR2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

243231:GS RS14235
gene id: 243231:GS_RS14235
uniprot id: Q749A9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

243231:GS RS00780
gene id: 243231:GS_RS00780
uniprot id: Q74GU3
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

243231:GS RS15345
gene id: 243231:GS_RS15345
uniprot id: Q3V8C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

243231:GS RS04340
gene id: 243231:GS_RS04340
uniprot id: Q74EU4
names: Subcellular Location Annotation
messages: Cytoplasm

243231:GS RS03375
gene id: 243231:GS_RS03375
uniprot id: Q74FD2
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS03010
gene id: 243231:GS_RS03010
uniprot id: P61422
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: In the C-terminal section; belongs to the ThiD family.
messages: In the N-terminal section; belongs to the thiamine-phosphate synthase family.

243231:GS RS03305
gene id: 243231:GS_RS03305
uniprot id: Q74FE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

243231:GS RS05095
gene id: 243231:GS_RS05095
uniprot id: Q74EE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane

243231:GS RS10080
gene id: 243231:GS_RS10080
uniprot id: Q74BN5
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS04245
gene id: 243231:GS_RS04245
uniprot id: Q74EW2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

243231:GS RS06065
gene id: 243231:GS_RS06065
uniprot id: Q74DU9
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS11330
gene id: 243231:GS_RS11330
uniprot id: Q74AU3
names: Similarity
messages: Belongs to the UPF0434 family.

243231:GS RS12660
gene id: 243231:GS_RS12660
uniprot id: Q74A69
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

243231:GS RS10440
gene id: 243231:GS_RS10440
uniprot id: Q74BG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

243231:GS RS08130
gene id: 243231:GS_RS08130
uniprot id: I7FK92
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

243231:GS RS08210
gene id: 243231:GS_RS08210
uniprot id: Q74CM9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

243231:GS RS01695
gene id: 243231:GS_RS01695
uniprot id: Q74GA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

243231:GS RS10380
gene id: 243231:GS_RS10380
uniprot id: Q74BH4
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

243231:GS RS15325
gene id: 243231:GS_RS15325
uniprot id: Q748F0
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

243231:GS RS14800
gene id: 243231:GS_RS14800
uniprot id: Q748Q9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

243231:GS RS09435
gene id: 243231:GS_RS09435
uniprot id: P61617
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

243231:GS RS10985
gene id: 243231:GS_RS10985
uniprot id: Q74B54
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS03275
gene id: 243231:GS_RS03275
uniprot id: Q74FF3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

243231:GS RS14245
gene id: 243231:GS_RS14245
uniprot id: Q749A7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

243231:GS RS01675
gene id: 243231:GS_RS01675
uniprot id: Q74GA9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

243231:GS RS09460
gene id: 243231:GS_RS09460
uniprot id: P61946
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

243231:GS RS10400
gene id: 243231:GS_RS10400
uniprot id: Q74BH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

243231:GS RS11880
gene id: 243231:GS_RS11880
uniprot id: Q74AI6
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

243231:GS RS01320
gene id: 243231:GS_RS01320
uniprot id: Q74GI0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

243231:GS RS00115
gene id: 243231:GS_RS00115
uniprot id: Q74H70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

243231:GS RS00515
gene id: 243231:GS_RS00515
uniprot id: Q74GZ6
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

243231:GS RS00795
gene id: 243231:GS_RS00795
uniprot id: Q74GU1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

243231:GS RS00435
gene id: 243231:GS_RS00435
uniprot id: Q74H10
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

243231:GS RS12835
gene id: 243231:GS_RS12835
uniprot id: Q74A36
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS05660
gene id: 243231:GS_RS05660
uniprot id: Q74E28
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

243231:GS RS13080
gene id: 243231:GS_RS13080
uniprot id: Q749Z1
names: Similarity
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.

243231:GS RS14345
gene id: 243231:GS_RS14345
uniprot id: P60454
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

243231:GS RS00130
gene id: 243231:GS_RS00130
uniprot id: Q74H67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

243231:GS RS14360
gene id: 243231:GS_RS14360
uniprot id: Q748Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

243231:GS RS04265
gene id: 243231:GS_RS04265
uniprot id: Q74EV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm

243231:GS RS14405
gene id: 243231:GS_RS14405
uniprot id: Q748Y1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

243231:GS RS03685
gene id: 243231:GS_RS03685
uniprot id: Q74F69
names: Subcellular Location Annotation
messages: Membrane

243231:GS RS17270
gene id: 243231:GS_RS17270
uniprot id: Q746S0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

243231:GS RS04365
gene id: 243231:GS_RS04365
uniprot id: Q74ET9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

243231:GS RS09195
gene id: 243231:GS_RS09195
uniprot id: Q74C42
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

243231:GS RS02600
gene id: 243231:GS_RS02600
uniprot id: Q74FT5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

243231:GS RS14210
gene id: 243231:GS_RS14210
uniprot id: Q749B3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.