2339259:D5F51 RS19370
gene id: 2339259:D5F51_RS19370
uniprot id: A0A481QI98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

2339259:D5F51 RS03955
gene id: 2339259:D5F51_RS03955
uniprot id: A0A481QAT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

2339259:D5F51 RS10700
gene id: 2339259:D5F51_RS10700
uniprot id: A0A481QE01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2339259:D5F51 RS15490
gene id: 2339259:D5F51_RS15490
uniprot id: A0A481QGN1
names: Subcellular Location Annotation
messages: Cytoplasm

2339259:D5F51 RS12585
gene id: 2339259:D5F51_RS12585
uniprot id: A0A481QFN5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

2339259:D5F51 RS14605
gene id: 2339259:D5F51_RS14605
uniprot id: A0A481QFW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

2339259:D5F51 RS20805
gene id: 2339259:D5F51_RS20805
uniprot id: A0A481QJ72
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

2339259:D5F51 RS06055
gene id: 2339259:D5F51_RS06055
uniprot id: A0A481QBU9
names: Subcellular Location Annotation
messages: Cytoplasm

2339259:D5F51 RS12105
gene id: 2339259:D5F51_RS12105
uniprot id: A0A481QFG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2339259:D5F51 RS05560
gene id: 2339259:D5F51_RS05560
uniprot id: A0A481QBM2
names: Similarity
messages: Belongs to the peptidase C40 family.

2339259:D5F51 RS20515
gene id: 2339259:D5F51_RS20515
uniprot id: A0A481QIN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2339259:D5F51 RS16980
gene id: 2339259:D5F51_RS16980
uniprot id: A0A481QGY3
names: Similarity
messages: Belongs to the UPF0253 family.

2339259:D5F51 RS00410
gene id: 2339259:D5F51_RS00410
uniprot id: A0A481Q934
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

2339259:D5F51 RS09235
gene id: 2339259:D5F51_RS09235
uniprot id: A0A481QJB0
names: Similarity
messages: Belongs to the UPF0263 family.

2339259:D5F51 RS20010
gene id: 2339259:D5F51_RS20010
uniprot id: A0A481QJX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AaeX family.
messages: Cell membrane

2339259:D5F51 RS02445
gene id: 2339259:D5F51_RS02445
uniprot id: A0A481Q974
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

2339259:D5F51 RS13720
gene id: 2339259:D5F51_RS13720
uniprot id: A0A481QFN0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

2339259:D5F51 RS05495
gene id: 2339259:D5F51_RS05495
uniprot id: A0A481QBD2
names: Similarity
messages: Belongs to the UPF0352 family.

2339259:D5F51 RS16060
gene id: 2339259:D5F51_RS16060
uniprot id: A0A481QFE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

2339259:D5F51 RS20585
gene id: 2339259:D5F51_RS20585
uniprot id: A0A481QHI7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2339259:D5F51 RS13730
gene id: 2339259:D5F51_RS13730
uniprot id: A0A481QFT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2339259:D5F51 RS03650
gene id: 2339259:D5F51_RS03650
uniprot id: A0A481Q9J0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

2339259:D5F51 RS17430
gene id: 2339259:D5F51_RS17430
uniprot id: A0A481QG67
names: Similarity
messages: Belongs to the ArsC family.

2339259:D5F51 RS20570
gene id: 2339259:D5F51_RS20570
uniprot id: A0A481QK49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2339259:D5F51 RS05200
gene id: 2339259:D5F51_RS05200
uniprot id: A0A481Q9G7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2339259:D5F51 RS16100
gene id: 2339259:D5F51_RS16100
uniprot id: A0A481QFF8
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

2339259:D5F51 RS03875
gene id: 2339259:D5F51_RS03875
uniprot id: A0A481Q9M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

2339259:D5F51 RS00335
gene id: 2339259:D5F51_RS00335
uniprot id: A0A481Q816
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2339259:D5F51 RS20260
gene id: 2339259:D5F51_RS20260
uniprot id: A0A481QIT4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

2339259:D5F51 RS22150
gene id: 2339259:D5F51_RS22150
uniprot id: A0A481QKS1
names: Similarity
messages: Belongs to the transposase 7 family.

2339259:D5F51 RS11255
gene id: 2339259:D5F51_RS11255
uniprot id: A0A481QCZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

2339259:D5F51 RS02370
gene id: 2339259:D5F51_RS02370
uniprot id: A0A481Q9E2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2339259:D5F51 RS13780
gene id: 2339259:D5F51_RS13780
uniprot id: A0A481QFU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

2339259:D5F51 RS20230
gene id: 2339259:D5F51_RS20230
uniprot id: A0A481QHB8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

2339259:D5F51 RS22125
gene id: 2339259:D5F51_RS22125
uniprot id: A0A481QKM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2339259:D5F51 RS08285
gene id: 2339259:D5F51_RS08285
uniprot id: A0A481QCI5
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

2339259:D5F51 RS20525
gene id: 2339259:D5F51_RS20525
uniprot id: A0A481QJ68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2339259:D5F51 RS20580
gene id: 2339259:D5F51_RS20580
uniprot id: A0A481QHY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2339259:D5F51 RS20620
gene id: 2339259:D5F51_RS20620
uniprot id: A0A481QK54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

2339259:D5F51 RS12635
gene id: 2339259:D5F51_RS12635
uniprot id: A0A481QFP4
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

2339259:D5F51 RS00305
gene id: 2339259:D5F51_RS00305
uniprot id: A0A481Q913
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

2339259:D5F51 RS20595
gene id: 2339259:D5F51_RS20595
uniprot id: A0A481QIK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2339259:D5F51 RS00265
gene id: 2339259:D5F51_RS00265
uniprot id: A0A481Q9D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

2339259:D5F51 RS22385
gene id: 2339259:D5F51_RS22385
uniprot id: A0A481QJV8
names: Similarity
messages: Belongs to the ArsC family.

2339259:D5F51 RS22325
gene id: 2339259:D5F51_RS22325
uniprot id: A0A481QL70
names: Function
messages: Involved in the transposition of the insertion sequence.

2339259:D5F51 RS15640
gene id: 2339259:D5F51_RS15640
uniprot id: A0A481QGL7
names: Similarity
messages: Belongs to the acetyltransferase family. YpeA subfamily.

2339259:D5F51 RS12560
gene id: 2339259:D5F51_RS12560
uniprot id: A0A481QEQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2339259:D5F51 RS22365
gene id: 2339259:D5F51_RS22365
uniprot id: A0A481QKA2
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

2339259:D5F51 RS05160
gene id: 2339259:D5F51_RS05160
uniprot id: A0A481QA73
names: Similarity
messages: Belongs to the UPF0304 family.

2339259:D5F51 RS20660
gene id: 2339259:D5F51_RS20660
uniprot id: A0A481QIC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2339259:D5F51 RS12645
gene id: 2339259:D5F51_RS12645
uniprot id: A0A481QDP8
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: The heme is bound between the two transmembrane subunits.

2339259:D5F51 RS22100
gene id: 2339259:D5F51_RS22100
uniprot id: A0A481QJA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

2339259:D5F51 RS01525
gene id: 2339259:D5F51_RS01525
uniprot id: A0A481Q973
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NusG family.
messages: Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.
messages: Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.

2339259:D5F51 RS17605
gene id: 2339259:D5F51_RS17605
uniprot id: A0A481QG50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

2339259:D5F51 RS22300
gene id: 2339259:D5F51_RS22300
uniprot id: A0A481QKG9
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

2339259:D5F51 RS20495
gene id: 2339259:D5F51_RS20495
uniprot id: A0A481QIH6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2339259:D5F51 RS12615
gene id: 2339259:D5F51_RS12615
uniprot id: A0A481QF50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

2339259:D5F51 RS05765
gene id: 2339259:D5F51_RS05765
uniprot id: A0A481Q9W8
names: Similarity
names: Subunit
messages: Belongs to the glutaredoxin family.
messages: Monomer.

2339259:D5F51 RS20270
gene id: 2339259:D5F51_RS20270
uniprot id: A0A481QK17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

2339259:D5F51 RS04520
gene id: 2339259:D5F51_RS04520
uniprot id: A0A481QBL1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

2339259:D5F51 RS06645
gene id: 2339259:D5F51_RS06645
uniprot id: A0A481QCQ9
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

2339259:D5F51 RS01200
gene id: 2339259:D5F51_RS01200
uniprot id: A0A481Q9T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

2339259:D5F51 RS02240
gene id: 2339259:D5F51_RS02240
uniprot id: A0A481Q858
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

2339259:D5F51 RS07795
gene id: 2339259:D5F51_RS07795
uniprot id: A0A481QBS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2339259:D5F51 RS20600
gene id: 2339259:D5F51_RS20600
uniprot id: A0A481QIV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2339259:D5F51 RS11495
gene id: 2339259:D5F51_RS11495
uniprot id: A0A481QEM8
names: Similarity
messages: Belongs to the CcmL/EutN family.

2339259:D5F51 RS17020
gene id: 2339259:D5F51_RS17020
uniprot id: A0A481QHH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

2339259:D5F51 RS11135
gene id: 2339259:D5F51_RS11135
uniprot id: A0A481QEE3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2339259:D5F51 RS12270
gene id: 2339259:D5F51_RS12270
uniprot id: A0A481QEZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2339259:D5F51 RS09530
gene id: 2339259:D5F51_RS09530
uniprot id: A0A481QDF8
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

2339259:D5F51 RS04950
gene id: 2339259:D5F51_RS04950
uniprot id: A0A481Q9B9
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

2339259:D5F51 RS22120
gene id: 2339259:D5F51_RS22120
uniprot id: A0A481QJD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

2339259:D5F51 RS13960
gene id: 2339259:D5F51_RS13960
uniprot id: A0A481QJU6
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

2339259:D5F51 RS03165
gene id: 2339259:D5F51_RS03165
uniprot id: A0A481Q9X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

2339259:D5F51 RS01530
gene id: 2339259:D5F51_RS01530
uniprot id: A0A481Q9Z3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2339259:D5F51 RS04465
gene id: 2339259:D5F51_RS04465
uniprot id: A0A481QBK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

2339259:D5F51 RS12650
gene id: 2339259:D5F51_RS12650
uniprot id: A0A481QDW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

2339259:D5F51 RS16340
gene id: 2339259:D5F51_RS16340
uniprot id: A0A481QGR3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2339259:D5F51 RS17830
gene id: 2339259:D5F51_RS17830
uniprot id: A0A481QG85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
messages: Monomer.

2339259:D5F51 RS14535
gene id: 2339259:D5F51_RS14535
uniprot id: A0A481QFV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

2339259:D5F51 RS22335
gene id: 2339259:D5F51_RS22335
uniprot id: A0A481QJN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

2339259:D5F51 RS07570
gene id: 2339259:D5F51_RS07570
uniprot id: A0A481QBP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism.

2339259:D5F51 RS10060
gene id: 2339259:D5F51_RS10060
uniprot id: A0A481QEF5
names: Similarity
messages: Belongs to the UPF0423 family.

2339259:D5F51 RS10440
gene id: 2339259:D5F51_RS10440
uniprot id: A0A481QE47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

2339259:D5F51 RS10775
gene id: 2339259:D5F51_RS10775
uniprot id: A0A481QDU3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2339259:D5F51 RS22155
gene id: 2339259:D5F51_RS22155
uniprot id: A0A481QK63
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

2339259:D5F51 RS13860
gene id: 2339259:D5F51_RS13860
uniprot id: A0A481QEH2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

2339259:D5F51 RS19380
gene id: 2339259:D5F51_RS19380
uniprot id: A0A481QID1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2339259:D5F51 RS10720
gene id: 2339259:D5F51_RS10720
uniprot id: A0A481QE99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

2339259:D5F51 RS21305
gene id: 2339259:D5F51_RS21305
uniprot id: A0A481QI65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

2339259:D5F51 RS20135
gene id: 2339259:D5F51_RS20135
uniprot id: A0A481QIN4
names: Subcellular Location Annotation
messages: Cytoplasm

2339259:D5F51 RS12575
gene id: 2339259:D5F51_RS12575
uniprot id: A0A481QF52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2339259:D5F51 RS12920
gene id: 2339259:D5F51_RS12920
uniprot id: A0A481QEF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2339259:D5F51 RS20625
gene id: 2339259:D5F51_RS20625
uniprot id: A0A481QJ83
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2339259:D5F51 RS11440
gene id: 2339259:D5F51_RS11440
uniprot id: A0A481QDM2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the bacterial microcompartments protein family.

2339259:D5F51 RS09535
gene id: 2339259:D5F51_RS09535
uniprot id: A0A481QD39
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

2339259:D5F51 RS20520
gene id: 2339259:D5F51_RS20520
uniprot id: A0A481QK44
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2339259:D5F51 RS13405
gene id: 2339259:D5F51_RS13405
uniprot id: A0A481QFH9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

2339259:D5F51 RS20535
gene id: 2339259:D5F51_RS20535
uniprot id: A0A481QHH6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2339259:D5F51 RS20055
gene id: 2339259:D5F51_RS20055
uniprot id: A0A481QIG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

2339259:D5F51 RS20510
gene id: 2339259:D5F51_RS20510
uniprot id: A0A481QIX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2339259:D5F51 RS09055
gene id: 2339259:D5F51_RS09055
uniprot id: A0A481QC89
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2339259:D5F51 RS17630
gene id: 2339259:D5F51_RS17630
uniprot id: A0A481QGX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LysR transcriptional regulatory family.
messages: Controls the transcription of genes involved in arginine and lysine metabolism.
messages: Homodimer.

2339259:D5F51 RS02190
gene id: 2339259:D5F51_RS02190
uniprot id: A0A481Q8W8
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity.

2339259:D5F51 RS02315
gene id: 2339259:D5F51_RS02315
uniprot id: A0A481Q991
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

2339259:D5F51 RS17770
gene id: 2339259:D5F51_RS17770
uniprot id: A0A481QG77
names: Similarity
messages: Belongs to the YggT family.

2339259:D5F51 RS21480
gene id: 2339259:D5F51_RS21480
uniprot id: A0A481QIF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2339259:D5F51 RS22110
gene id: 2339259:D5F51_RS22110
uniprot id: A0A481QJ01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

2339259:D5F51 RS16710
gene id: 2339259:D5F51_RS16710
uniprot id: A0A481QFW6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

2339259:D5F51 RS10660
gene id: 2339259:D5F51_RS10660
uniprot id: A0A481QE90
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

2339259:D5F51 RS19965
gene id: 2339259:D5F51_RS19965
uniprot id: A0A481QJN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rnk family.
messages: Interacts with the RNA polymerase.
messages: May act as an anti-Gre factor.

2339259:D5F51 RS17090
gene id: 2339259:D5F51_RS17090
uniprot id: A0A481QH04
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2339259:D5F51 RS13625
gene id: 2339259:D5F51_RS13625
uniprot id: A0A481QFD5
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

2339259:D5F51 RS16125
gene id: 2339259:D5F51_RS16125
uniprot id: A0A481QGS5
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

2339259:D5F51 RS21935
gene id: 2339259:D5F51_RS21935
uniprot id: A0A481QJ76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

2339259:D5F51 RS20505
gene id: 2339259:D5F51_RS20505
uniprot id: A0A481QI97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

2339259:D5F51 RS20555
gene id: 2339259:D5F51_RS20555
uniprot id: A0A481QIA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2339259:D5F51 RS07765
gene id: 2339259:D5F51_RS07765
uniprot id: A0A481QB37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

2339259:D5F51 RS03965
gene id: 2339259:D5F51_RS03965
uniprot id: A0A481QBD8
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

2339259:D5F51 RS02155
gene id: 2339259:D5F51_RS02155
uniprot id: A0A481Q9W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

2339259:D5F51 RS13865
gene id: 2339259:D5F51_RS13865
uniprot id: A0A481QFK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

2339259:D5F51 RS07770
gene id: 2339259:D5F51_RS07770
uniprot id: A0A481QBP1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2339259:D5F51 RS20610
gene id: 2339259:D5F51_RS20610
uniprot id: A0A481QIZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2339259:D5F51 RS13875
gene id: 2339259:D5F51_RS13875
uniprot id: A0A481QFQ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

2339259:D5F51 RS13895
gene id: 2339259:D5F51_RS13895
uniprot id: A0A481QGC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

2339259:D5F51 RS10670
gene id: 2339259:D5F51_RS10670
uniprot id: A0A481QEU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2339259:D5F51 RS20575
gene id: 2339259:D5F51_RS20575
uniprot id: A0A481QJ74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2339259:D5F51 RS19830
gene id: 2339259:D5F51_RS19830
uniprot id: A0A481QIJ5
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

2339259:D5F51 RS20540
gene id: 2339259:D5F51_RS20540
uniprot id: A0A481QJ14
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2339259:D5F51 RS05925
gene id: 2339259:D5F51_RS05925
uniprot id: A0A481QAK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2339259:D5F51 RS20560
gene id: 2339259:D5F51_RS20560
uniprot id: A0A481QIY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2339259:D5F51 RS09830
gene id: 2339259:D5F51_RS09830
uniprot id: A0A481QDS5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

2339259:D5F51 RS22295
gene id: 2339259:D5F51_RS22295
uniprot id: A0A481QK68
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

2339259:D5F51 RS21950
gene id: 2339259:D5F51_RS21950
uniprot id: A0A481QIX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

2339259:D5F51 RS05625
gene id: 2339259:D5F51_RS05625
uniprot id: A0A481QB38
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

2339259:D5F51 RS06575
gene id: 2339259:D5F51_RS06575
uniprot id: A0A481QB90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

2339259:D5F51 RS19680
gene id: 2339259:D5F51_RS19680
uniprot id: A0A481QHV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SIS family. DiaA subfamily.
messages: Homotetramer; dimer of dimers.
messages: Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.

2339259:D5F51 RS13980
gene id: 2339259:D5F51_RS13980
uniprot id: A0A481QFF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

2339259:D5F51 RS11960
gene id: 2339259:D5F51_RS11960
uniprot id: A0A481QEU7
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

2339259:D5F51 RS04530
gene id: 2339259:D5F51_RS04530
uniprot id: A0A481Q949
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

2339259:D5F51 RS07775
gene id: 2339259:D5F51_RS07775
uniprot id: A0A481QCG8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2339259:D5F51 RS06860
gene id: 2339259:D5F51_RS06860
uniprot id: A0A481QBD3
names: Subcellular Location Annotation
messages: Cytoplasm

2339259:D5F51 RS10900
gene id: 2339259:D5F51_RS10900
uniprot id: A0A481QD28
names: Subcellular Location Annotation
messages: Cytoplasm

2339259:D5F51 RS20615
gene id: 2339259:D5F51_RS20615
uniprot id: A0A481QIQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2339259:D5F51 RS16210
gene id: 2339259:D5F51_RS16210
uniprot id: A0A481QFH7
names: Similarity
messages: Belongs to the P(II) protein family.

2339259:D5F51 RS10865
gene id: 2339259:D5F51_RS10865
uniprot id: A0A481QDA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

2339259:D5F51 RS14690
gene id: 2339259:D5F51_RS14690
uniprot id: A0A481QGY7
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

2339259:D5F51 RS00250
gene id: 2339259:D5F51_RS00250
uniprot id: A0A481Q837
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2339259:D5F51 RS13725
gene id: 2339259:D5F51_RS13725
uniprot id: A0A481QEV8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2339259:D5F51 RS04310
gene id: 2339259:D5F51_RS04310
uniprot id: A0A481QBI5
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

2339259:D5F51 RS20550
gene id: 2339259:D5F51_RS20550
uniprot id: A0A481QIU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

2339259:D5F51 RS13595
gene id: 2339259:D5F51_RS13595
uniprot id: A0A481QEC3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2339259:D5F51 RS14545
gene id: 2339259:D5F51_RS14545
uniprot id: A0A481QG07
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

2339259:D5F51 RS11650
gene id: 2339259:D5F51_RS11650
uniprot id: A0A481QEJ2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

2339259:D5F51 RS11575
gene id: 2339259:D5F51_RS11575
uniprot id: A0A481QD54
names: Similarity
messages: Belongs to the UPF0265 family.

2339259:D5F51 RS21945
gene id: 2339259:D5F51_RS21945
uniprot id: A0A481QJM5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2339259:D5F51 RS16135
gene id: 2339259:D5F51_RS16135
uniprot id: A0A481QGU1
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster.
messages: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.

2339259:D5F51 RS19740
gene id: 2339259:D5F51_RS19740
uniprot id: A0A481QJT5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2339259:D5F51 RS12110
gene id: 2339259:D5F51_RS12110
uniprot id: A0A481QF20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2339259:D5F51 RS00575
gene id: 2339259:D5F51_RS00575
uniprot id: A0A481Q963
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Does not bind DNA by a helix-turn-helix motif.
messages: Homodimer.
messages: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.

2339259:D5F51 RS03960
gene id: 2339259:D5F51_RS03960
uniprot id: A0A481QAA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

2339259:D5F51 RS20645
gene id: 2339259:D5F51_RS20645
uniprot id: A0A481QIL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2339259:D5F51 RS20590
gene id: 2339259:D5F51_RS20590
uniprot id: A0A481QJ24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2339259:D5F51 RS01520
gene id: 2339259:D5F51_RS01520
uniprot id: A0A481Q9K7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2339259:D5F51 RS02470
gene id: 2339259:D5F51_RS02470
uniprot id: A0A481Q894
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2339259:D5F51 RS00545
gene id: 2339259:D5F51_RS00545
uniprot id: A0A481Q7E3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

2339259:D5F51 RS16370
gene id: 2339259:D5F51_RS16370
uniprot id: A0A481QGZ8
names: Function
messages: Acts as a radical domain for damaged PFL and possibly other radical proteins.

2339259:D5F51 RS01340
gene id: 2339259:D5F51_RS01340
uniprot id: A0A481Q8S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate.
messages: Cytoplasm

2339259:D5F51 RS00895
gene id: 2339259:D5F51_RS00895
uniprot id: A0A481Q8E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

2339259:D5F51 RS17125
gene id: 2339259:D5F51_RS17125
uniprot id: A0A481QHJ6
names: Similarity
messages: Belongs to the UPF0325 family.

2339259:D5F51 RS08900
gene id: 2339259:D5F51_RS08900
uniprot id: A0A481QCU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2339259:D5F51 RS02740
gene id: 2339259:D5F51_RS02740
uniprot id: A0A481QAF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

2339259:D5F51 RS20545
gene id: 2339259:D5F51_RS20545
uniprot id: A0A481QII8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

2339259:D5F51 RS20605
gene id: 2339259:D5F51_RS20605
uniprot id: A0A481QIB7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2339259:D5F51 RS00405
gene id: 2339259:D5F51_RS00405
uniprot id: A0A481Q873
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

2339259:D5F51 RS13795
gene id: 2339259:D5F51_RS13795
uniprot id: A0A481QGA0
names: Similarity
messages: Belongs to the UPF0234 family.

2339259:D5F51 RS02025
gene id: 2339259:D5F51_RS02025
uniprot id: A0A481Q943
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2339259:D5F51 RS13715
gene id: 2339259:D5F51_RS13715
uniprot id: A0A481QFB2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2339259:D5F51 RS08050
gene id: 2339259:D5F51_RS08050
uniprot id: A0A481QB84
names: Cofactor
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.

2339259:D5F51 RS02050
gene id: 2339259:D5F51_RS02050
uniprot id: A0A481Q9U1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

2339259:D5F51 RS06065
gene id: 2339259:D5F51_RS06065
uniprot id: A0A481QCE9
names: Similarity
messages: Belongs to the UPF0434 family.

2339259:D5F51 RS01540
gene id: 2339259:D5F51_RS01540
uniprot id: A0A481Q7U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2339259:D5F51 RS02410
gene id: 2339259:D5F51_RS02410
uniprot id: A0A481Q885
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

2339259:D5F51 RS00525
gene id: 2339259:D5F51_RS00525
uniprot id: A0A481Q953
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapB family.
messages: Cytoplasm
messages: Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.
messages: Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.

2339259:D5F51 RS20265
gene id: 2339259:D5F51_RS20265
uniprot id: A0A481QIJ9
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

2339259:D5F51 RS02340
gene id: 2339259:D5F51_RS02340
uniprot id: A0A481Q9K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

2339259:D5F51 RS21300
gene id: 2339259:D5F51_RS21300
uniprot id: A0A481QKD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein B family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

2339259:D5F51 RS20115
gene id: 2339259:D5F51_RS20115
uniprot id: A0A481QJ05
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

2339259:D5F51 RS06475
gene id: 2339259:D5F51_RS06475
uniprot id: A0A481QB74
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2339259:D5F51 RS21375
gene id: 2339259:D5F51_RS21375
uniprot id: A0A481QI76
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

2339259:D5F51 RS19210
gene id: 2339259:D5F51_RS19210
uniprot id: A0A481QIA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

2339259:D5F51 RS13660
gene id: 2339259:D5F51_RS13660
uniprot id: A0A481QFG8
names: Similarity
messages: Belongs to the P(II) protein family.

2339259:D5F51 RS06450
gene id: 2339259:D5F51_RS06450
uniprot id: A0A481QAC0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2339259:D5F51 RS21005
gene id: 2339259:D5F51_RS21005
uniprot id: A0A481QHY6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

2339259:D5F51 RS20665
gene id: 2339259:D5F51_RS20665
uniprot id: A0A481QJ06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2339259:D5F51 RS03575
gene id: 2339259:D5F51_RS03575
uniprot id: A0A481QJF0
names: Function
names: Similarity
messages: Belongs to the thr operon leader peptide family.
messages: This protein is involved in control of the biosynthesis of threonine.

2339259:D5F51 RS02365
gene id: 2339259:D5F51_RS02365
uniprot id: A0A481Q996
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2339259:D5F51 RS01365
gene id: 2339259:D5F51_RS01365
uniprot id: A0A481Q948
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

2339259:D5F51 RS00330
gene id: 2339259:D5F51_RS00330
uniprot id: A0A481Q7B4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2339259:D5F51 RS20890
gene id: 2339259:D5F51_RS20890
uniprot id: A0A481QK92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

2339259:D5F51 RS09810
gene id: 2339259:D5F51_RS09810
uniprot id: A0A481QDK4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

2339259:D5F51 RS05600
gene id: 2339259:D5F51_RS05600
uniprot id: A0A481QB54
names: Similarity
messages: Belongs to the elongation factor P family.

2339259:D5F51 RS00530
gene id: 2339259:D5F51_RS00530
uniprot id: A0A481Q8S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

2339259:D5F51 RS08040
gene id: 2339259:D5F51_RS08040
uniprot id: A0A481QCX3
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.
messages: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters.

2339259:D5F51 RS07970
gene id: 2339259:D5F51_RS07970
uniprot id: A0A481QDG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

2339259:D5F51 RS07800
gene id: 2339259:D5F51_RS07800
uniprot id: A0A481QCR6
names: Subcellular Location Annotation
messages: Membrane

2339259:D5F51 RS22255
gene id: 2339259:D5F51_RS22255
uniprot id: A0A481QKH4
names: Similarity
messages: Belongs to the peptidase S24 family.